| Trustees and Officers | 2-3 | |
|---|---|---|
| Chairman's Statement |
4-5 | |
| Trustees' Report | 6-9 | |
| Statement ofTrustees' responsibilities | ||
| Report ofthe Independent | Examiner ... | 10 |
| Grants awarded | ||
| Statement ofFinancial Activities | 12 | |
| Balance sheet | 13 | |
| Cash Flow Statement | 14 | |
| Notes to the Financial Statements | 15-20 |
| Professor Sir Charles George | Professor Sir Charles George | Chairman | (appointed 22.04.22) |
(appointed 22.04.22) |
||
|---|---|---|---|---|---|---|
| Roger Allsopp | ||||||
| Professor Jonathan | Cole | |||||
| Tony Cottam | ||||||
| Professor Max Crispin | ||||||
| Professor Diana Eccles | Dean ofthe Faculty ofMedicine, | University | of Southampton) | |||
| Terry Madden | Chairman | (Retired 22.04.22) | ||||
| Luke March | ||||||
| Nick Page | ||||||
| Angela Suggate FCCA | ||||||
| Michael Wilkins | Retired 14.10.22 | |||||
| Officers and Advisers | ||||||
| Independent Examiner |
PEH Wright | FCA DChaA | ||||
| Sheen Stickland | ||||||
| Chartered Accountants |
||||||
| Statutory Auditors | ||||||
| 7East Pallant | ||||||
| Chichester | ||||||
| West Sussex | ||||||
| PO19 1TR | ||||||
| Honorary Solicitors |
Womble Bond Dickinson (UK) | LLP | ||||
| Oceana House | ||||||
| Commercial | Road | |||||
| Southampton | ||||||
| SO151GA |
| Professor Nick Evans | Chairman | Faculty of | Medicine, University | ofSouthampton. |
|---|---|---|---|---|
| Mr Brian Birch | Faculty of | Medicine, University | ofSouthampton | |
| Dr Jeremy Blaydes | Faculty of | Medicine, University | ofSouthampton | |
| Dr Katrin Deinhardt | Faculty of | Environmental and Life Sciences |
||
| University | ofSouthampton | |||
| Dr Jana Kreppner | Faculty of | Environmental and Life Sciences |
||
| University | ofSouthampton | |||
| Professor Deborah Mackay | Faculty of | Medicine, University | ofSouthampton | |
| Professor Sumeet Mahajan | Faculty of | Physical Sciences and Engineering | ||
| University | ofSouthampton | |||
| Professor Tiina Roose | Faculty of | Physical Sciences and Engineering, | ||
| University | ofSouthampton | |||
| Professor Tilman Sanches-Elsner | Faculty of | Medicine, University | ofSouthampton | |
| Professor Jon Strefford | Faculty of | Medicine, University | ofSouthampton | |
| Dr Will Tapper | Faculty of | Medicine, University | ofSouthampton | |
| Dr Dawn-Marie Walker |
Faculty of | Environmental and Life Sciences, |
||
| University | ofSouthampton | |||
| Dr Yihua Wang | Faculty of | Environmental and Life Sciences, |
||
| University | ofSouthampton |
| Grantee | ||||||||
|---|---|---|---|---|---|---|---|---|
| Research Project | ||||||||
| AC01 | Dr Juliet Gray | 55,000 | ||||||
| Faculty ofMedicine | ||||||||
| PhD Studentshi pjointly funded | with the Centre | forCancer | Immunology | |||||
| Student-Nubia Castillo |
||||||||
| Enhancing anti-GD2 chemwimmunotherapyin |
pre-clinical | neuroblastoma | ||||||
| models. | ||||||||
| AC02 | Dr Yury Bogdanov | 55,000 | ||||||
| Faculty of Medicine | ||||||||
| PhD Studentshi pjointly funded | with the Centre | forCancer | Immunology | |||||
| Student-Kaj aStoklaaa | ||||||||
| Deciphering the role ofGABAergic signallingin |
tumour vascularization | |||||||
| AC03 | Professor Karen Lillycrop | 31,386 | ||||||
| Faculty ofthe Environment | and Life Sciences | |||||||
| PhD Studensthi pjointly funded | with Rosetrees | Trust | ||||||
| Student-4faisha Chaudery |
||||||||
| Identifying the causes ofmuscle stem |
cellaging | and novel | therapeutics | |||||
| strategies | ||||||||
| AC04 | 3' Year Medical Student | Project Presentation | Grants | 1,000 | ||||
| AC05 | Dr Niall Hanrahan | 17,917 | ||||||
| Faculty ofEngineering and |
Physical Sciences | |||||||
| Raman-on-a-chip forlabel-free and culture-freeidentification |
ofVBNCs | |||||||
| AC06 | Dr Jade Forster | 19,943 | ||||||
| Faculty ofMedicine | ||||||||
| Identifying the underlying |
molecular mechanisms | and alterations ofthe high- | ||||||
| risk neuroblastoma tumour |
microenvironmentin | TH-MYCNmice treated with | ||||||
| anti-GD2 antibody therapy. | ||||||||
| AC07 | Dr Andrew Shapanis | 19,900 | ||||||
| Faculty ofthe Environment | and Life Sciences | |||||||
| Development and optimisation ofaserum based early cancer diagnostic |
||||||||
| system | ||||||||
| Annual Total 2022 |
200,146 | |||||||
| Annual Total2021 |
110,919 |
| ~ | ~ | ~ | ~ | |||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| ~ | ~ | |||||||||||||||||||||||||||||||||||||
| ~ | ~ | ~ |
| Balance Sheet asat 31 | "December 2022 | |||
|---|---|---|---|---|
| Note | 2022 | 2021 | ||
| F | ||||
| Fixed Assets | ||||
| Tangible Assets | 10 | |||
| Investments | 11 | 1,724,581 | 1,339,252 | |
| 1,724,581 | 1,339,252 | |||
| Current Assets | ||||
| Investments | 12 | 31,503 | ||
| Debtors | 13 | 139,382 | 50,512 | |
| Short Term Deposits | 200,000 | |||
| Cash at bank and in hand | 45,029 | 670,924 | ||
| 384,411 | 752,939 | |||
| Current Liabilities |
||||
| Amounts falling due within |
one year | 14 | (246,171) | (256,993) |
| Net Current Assets I(Liabilities) | 138,240 | 495,946 | ||
| Total Assets less Current | Liabilities | 1,862,821 | 1,835,198 | |
| Liabilities | ||||
| Amounts falling due alter more than one year |
15 | (213,262) | (171,019) | |
| Net Assets | 16 | 1,649,559 | 1,664,179 | |
| Funds | ||||
| Unrestricted | General | 18 | 1,571,342 | 541,698 |
| Restricted | 17 | 78,217 | 1,122,481 | |
| Total Funds | 1,649,559 | 1,664,179 |
| 2022 | 2021 | |||||
|---|---|---|---|---|---|---|
| Cash from Operating Activities |
Note 1 | (45,612) | 840,846 | |||
| Cash Row from Investing | ||||||
| Purchase ofFixed Asset Investments Sale ofFixed Asset Investments Sale ofCurrent Asset Investments |
(800,000) 300,000 28,425 |
(500,000) 150,000 |
||||
| Distributions Received |
91,292 | 50,903 | ||||
| (380,283) | (299,097) | |||||
| Change in cash and cash equivalents |
in the period | (425,895) | 541,749 | |||
| Cash and cash equivalents at 1stJanuary |
2022 | 670,924 | 129,175 | |||
| Cash and cash equivalents at 31st |
December 2022 | 245,029 | 670924, |
| Cash from operating Activities |
||||
|---|---|---|---|---|
| Net income/(expenditure) I'or reporting |
period per SOFA | (14,620) | 1,124,486 | |
| Adjustments Ior: |
||||
| Distributions receiMsd Decrease/(increase) in Debtors Increase in Creditors (Decrease)/increase in Grants (Gain)/Loss on Investments |
payable | (91,292) (88,870) 1,719 29,702 117,749 |
(50,903) 92 1,482 (114,957) (119,354) |
|
| (45,612) | 840,846 |
| ~ | ~ | . | f | ~ | ||||
|---|---|---|---|---|---|---|---|---|
| ~ | ~ | ~ | ~ | |||||
| ~ | ~ | |||||||
| ~ | ~ |
| 0 | ~ | ~ | ~ | ~ | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ~ | ~ | ~ | " | ~ | ~ | |||||
| ~ | ~ | ~ | ~ |
| ~ | ~ | ~ | |||
|---|---|---|---|---|---|
| ~ | ~ | ~ | |||
| ~ | - | L |
| 6. Allocatio |
n ofSupport Costs | |||
|---|---|---|---|---|
| Raising | Charitable | Total | ||
| Funds | Activities | |||
| f | f | |||
| Oflice Costs | 1,482 | 1,095 | 2,577 | |
| Professional | Fees | 10,665 | 16,550 | 27,215 |
| Audit Fees | 2,700 | 2,700 | ||
| 12,147 | 20,345 | 32,492 |
| 2022 | 2021 | |||||
|---|---|---|---|---|---|---|
| f | ||||||
| Independent | Examiners | SeNIces | / | Auditors | 2,700 | 3,900 |
| 2,700 | 3,900 |
| Fixtures, Fittings | Fixtures, Fittings | ||||
|---|---|---|---|---|---|
| Costat1" January 2022 |
and | Equipment f 190 |
|||
| Additions | |||||
| Disposals | |||||
| Cost at31" December 2022 | 190 | ||||
| Accumulated depreciation |
at 1" January | 2022 | 190 | ||
| Charge Ibr year | |||||
| Disposals | |||||
| Accumulated depreciation |
at31" December 2022 | 190 | |||
| Net Book Value | |||||
| 31" December 2022 | |||||
| 31" December 2021 | |||||
| 11.Investments at market value: fixed assets |
|||||
| Equities | |||||
| Market Value at 1stJanuary Additions |
2022 | 1,339,252 | |||
| Disposals Unrealised Loss for the year |
800,000 (300,000) |
||||
| Realised Loss for the year Market value at 31stDecember 2022 |
(94,755) (19,916) 1,724,581 |
||||
| The historical cost ofinvestments (2021:R1,151,123). |
at 31"December 2022 amounted | to 81,727,935 |
| 12.Investments at market v |
alue: current assets | |
|---|---|---|
| Government Stocks |
||
| Market Value at 1stJanuary Additions |
2022 | 31,503 |
| Disposals Realised loss in year Market value at 31stDecember 2022 |
(28,424) (3,079) |
| 13. Debtors | |||
|---|---|---|---|
| 2022 | 2021 | ||
| Other debtors | 139,382 | 50,095 | |
| Prepay ments | 417 | ||
| 139,382 | 50,512 | ||
| 14.Creditors: amounts | falling due within one year | ||
| 2022 | 2021 | ||
| E | E | ||
| Grants payable | 236,435 | 248,976 | |
| Trade creditors | 2,801 | ||
| Accruals | 6,935 | 8,017 | |
| 246,171 | 256,993 |
| 15.Cr | editors: amounts falling due after |
more than one year | |
|---|---|---|---|
| 2022 | 2021 | ||
| Grants | payable | 213,262 | 171,019 |
| 213,262 | 171,019 |
| Unrestricted | Restricted | Total | ||||||
|---|---|---|---|---|---|---|---|---|
| Funds | Funds | Funds | ||||||
| R | ||||||||
| Fixed | Assets | 1,724,581 | 1,724,581 | |||||
| Current | Assets | 280,832 | 103,579 | 384,411 | ||||
| Current | Liabilities | (233,670) | (12,501) | (246,171) | ||||
| Amounts | tailing | due | alter | more | ||||
| than | 1 year | (200,401) | (12,861) | (213,262) | ||||
| Total | Net Assets | 1,571,342 | 78,217 | 1,649,559 |
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