REGISTERED COMPANY NUMBER: 01256124 (England and Wales) REGISTERED CHARITY NUMBER: 273670 REPORT OF THE TRUSTEES AND UNAUDITED FINANCIAL STATEMENTS FOR THE YEAR EIYDED 31 ocfoBER 2025 FOR THE NATIONAL SOCIETY FOR PHENYLKETONURIA (UNTTED KTNGDOM) LIMITED (A COIKPANY LIMITLD BY GUARANTEE) Hayes & Co St Andrews Hou 3 Tarleton office Park Wind8atc Tarleton PR4 6JF
THE NATIONAL SOCIETY FOR PHENYLKETONURIA (uNrtED KTNGDOM) LIMITED CONTENTS OF THE FINANCIAL STATEMENTS for the year ended 31 Octtrber 2025 PAge Report of the Trujteej I to 5 Independent Examiner's Report St*temeDt of Fln8ndal Attlirfd Balance Sheet 8 to 9 Notd to tht Fln•n¢l•l Statements 10 to 16
THE NATIONAL SOCIETY FOR PHENYLKETONURIA (UNITED KtNGDOM) LIMITED IREGISTERED NUMBER.. 111256124) REPORT OF THE TRUSTEES for the yegr ended 31 Ottober 2025 The trustees who are a150 directors of the charity for th£ purposes of the Companies Act 2006, prescnt their report with the financial statements of the charity for the year ended 31 Ocrober 2024, which are prepared to meet the iEquirements for d 15irec¢ors' report and atcount5' for Companies Act purposes.The trustees have adopted the provisions of Accounting and reporting by Chariiies.'Statement of Rccommcnded Practice applicable to charities prqiaring their accounts in accordance with the Financial Reporting Standard appli¢8ble to the UK and R¢publi¢ of Ireland IFRS 1021 effective I January 20191. The fUnCl8[ statem¢nts hav¢ Ix¢n pr¢par¢d in a¢¢OTd8nc¢ with the 8ccowi¢ing polici¢y set out in the notrs to th¢ a¢¢owits and comply with the charity's goveming documenL the Charities Act 2011 and Accouniing and Reporting by Chan(ie5.'Stat¢rn¢nt of R¢wmmended Practic¢ ?ppli¢ablc in th¢ UK and R¢public of Ir¢land publish¢d. OWECTIVES AND ACTIVITIES Objeelives and aims Th¢ obje¢tiv¢$ of the charity are io promote the educational, medical and social welfare of persons suff¢riDg from phcnylkctonuria IPKUI and similar disorders controlled by diet,. to encourage research into PKU anKI rclated disorders: to ¢5tablish and maintain funds from which gran may be made to fijrther thc chariry's objectives,. and to snvit, procure, collect and re¢eive donations, subtscriptions. legacies and other gifts. The Trusrtts have had regard the Charity Commission'5 8uidancc on public benefit when reviewing the chariry's aims and objeciivcs and whrn pl8nning its activitie5. Phcnylketonuria (PKU) is a Tllrc inheTiLcd mctaEx>lic disord affecting the body'5 ability to brcak down the amino acid phtnylalanine. Without treatment, phenylalanine accumulates in the blood and brain and Con cause rioUS neurological damage. In the United Kingdom PKU is id¢niified through n¢wbom scr¢¢ning shonly after bitth, enabling treatTn¢nt to bEgin early. Managcmcnt typically involves a sirict lifelong low-phenylalanine diet supported by specialist lTrw-protcin foods And Protein &ub¥lltulc5. Although treatrnent ha5 Si8nificantly improv¢d out¢om¢5. rnana8LfL8 PKU rcquircs ongoirjg dictary moniL()rin8 and ¢lini¢al suryI$l0n and can prcsent Significant ¢hall¢ngcs for individua15 and familie5. Through puti¢nt 5UPPOrt, education, Rdvocacy and research. NSPKU works lo imprvve the lives of individuals and familie6 Affected by PKU and allicd conditions controllcd by diet. Grntmklng pollcy The allocation of grat)ts is d¢¢id¢d on an individual b¥sis as wn gpplication is made. The appli¢aLion wher¢ Njsgible will be discu&%ed by the Cowicil of Managemenl (anonymously if nccessaryl but if this is noi p)ssible a decision will b made by the senior oifieers and tninutes taken #t the next Committe of Managemenl tneeting. Where applitable. we sho11 seek guidance frorn OUT Medical Advisory Punel. Volunteers All members of the Council of Man¢M¢t voluntc¢rs. Th¢y ar¢ ¢ncourag to contribut¢ frwly to all discussions and decisions made by the Council. Meetings have minutes taken to reflect discussion5, decisions at]d dissenlions. Page I
THE NATIONAL SOCIETY FOR PHENYLKETONUIUA {UNrrED KtNGDOM) LIMfrED {REGISTERED NUMBER: 01256124) REPORT OF THE TRUSTEES for the year ended 31 October 2025 ACHIEVEMENTS AND PERFORMANCE Overview During the year NSPKU continu¢d to d¢liver activilies supwrting individuals and families affected by PKU across th¢ United Kingdorn. Th¢s¢ in¢lud¢d paticnt supw)rt services, rc%carch iniiiaiives. advocacy work, cornlniiniry engagement activities and fiu)draising. Patient Support and Community Engagement Providing SUPPOrt and reliable infonnation to individua15 arml families livin8 with PKU remains centrdl to th¢ chpTity's Work. NSPKU continued to operate its helpline. providing advice, infornialion and cmotional support to patients, parents, carers and hcalthcar¢ profcSSLonals. Thc charity engage5 the Services of 3 specialist rn¢taboli¢ diclitian who provides expcrt guidance and contributes to the devclopTncni of diclary resources and educational mateiiAIs to assist individuals in rnanA8ing ihe complcx low-phcnyl?lanin¢ dict Tcquir¢d for PKU. Th¢ charity maiftthirts a dctailed wcbsiie which provided esseniial, accuratc pnd d¢tail¢d infonnation regardJ"n8 the dietary ¢Teathient of peryjlc wilh PKU. This informalion 15 r¢li¢d on by paticnts, carers and healthcare professionals. Community engagement activities help reduce isolation and strenhen connections within the PKU cornmuniry. In April 2025 NSPKU hostcd a community conferen¢¢ in Cumbernauld. Gla58ow. attended by approximatcly 200 m¢mb¢rs of rhe PKU community. The progrnmme included educational presentsti¢)n$, panel discussions and cooking demonstrations f¢aturin8 low-proiein focrfi8. A Wales Day Conference wlls also held in CarditT in Oclob¢r 2025, providing members with opportunitiC5 10 informatiort. share cxpcriences and conne<1 with oihers livin8 With PKU. Research Supporting researeh into PKU remains & key priority for NSPKU. During the year the charity establi5hcd a R&se4rch Strategy Group. bringing togethcr patient reprts¢ntative$, &dvocAtes And clinicians to strenhen Ihe NSPKU r¢s¢h framcwoTk and idcntify research pritiriiies. The group advises the Council of MJnJg¢ment and cnsures thAt the experiences of the PKU ¢ommunity infoTh research activity. The group b¢8an dcv¢loping th¢ charity's first forn7 Research Strategy and strength¢nin8 lati1)nshIpS with healihcarc professionals, academic ins¢ilution5 and industry partners. In November 2024 NSPKU launched a Research Gran¢ Award 5ehcme. inviting applic&lions fur projKts b¢tw¢¢n £5,000 artd £1 O.IMM). wilh total funding of up to £50,000. Following &sscssm¢nt by NSPKU and lis Medical Advisory Panel, six re5ewch granls were awarded covering ¥agtroiniesiinal symptonKs in people with PKU, paLicnt pr&cti¢es laling to $4)ropterin administration. thc effect of ihe PKU diet on gut mierobiotA in children. variation in phenylalanine levels thr¢ng the menstsual cycle, tb¢ prevalence and impacl of autistic spectwm disorder in individua]5 with PKU, and the long-term irnpact of sapropterin on diet quality and Caregiv burden in childn. Policy and Advocacy NSPKU coniinued i($ advocacy work ro ensure that the needs of people ILVIII8 Wlth PKU arc represented in healrhcare policy public awaTene5s initiatives. During the year the charity en8a8ed with Ofcom reg8rdin8 prowsed changes to postal services, highli8ELtin8 the IMrtanCe of reliable delivery seryiccs for individual8 who rely on spccialist dietsry pmducls. The charity also conducted a survey of Scottish members regarding their experienc&s of metabolic setvices. Re4x)nses indicated ¢on¢ern5 about ¢on5iSt¢ncy of services and access to treamients, pBrticularly sapropt#in for adults. In response. the chan'ty began plat]ning an advocacy event in the Scottish Parlikmeni. Page 2
THE NATIONAL SOCIETY FOR PHENYLKETONURtA {UMTED KtNGDOM) LIMITED (REGISTERED NUMBER: 01256124) REPORT OF THE TRUSTEES for the year ended 31 October 2025 In Northem Ireland the PKU cornmunity organi5ed awareness-rai5ing activitie5 to mark International PKU Day 2025, with several local authorilies illuminating landmark buildings in green to rdise dwarelles5 of PKU. Medical Advisory Panel Th¢ Medical Advisory P8n¢l IMAP) continued to provide expert odvic¢ to the Cguncil of Mana¥ement on clinical. dieteiic and psychological aspects of PKU care across the UK. Th¢ paT]el includes patient r¢pTG8¢ntativ¢s alongside expetienc¢d clinicians dietitians. Its work supports high standards of clinical care. strengthens engagcment with PKU clinics and facilitates dialogue with .5pccialis¢ food and fonnula manufacturcrs. DHPR deficiency Th¢ ¢harity, with th¢ advic¢ from LliniLi>m4 confe thaL support for DHPR d¢ficicncy was within Its Lharilttblc objcclives. DHPR deficicncy is one of ihe BH4 deficiencies thai can initially pre*nt with raised phenylalanine levels on newburn gL'reenin¥. Awareness.ra]5in activities highlighted the syrnptorns, dI80$1S Jnd treulmeni pathways for this rarc condition. Thc charity is coniinuing to develop support for paiienis and familics affected by DHPR defjeitncy. Fundraising FundrdiSin8 2¢tiviti¢s during the year continucd to provid¢ cssential support for the charity-s work. Communiry-led fijndraising iniiialives took place acro the UK. raising rtds dnd awarene&s for PKU. Income gcncrJlcd through Ih¢¥e ctLVitICS 5upporLs rc5earch init131ives, patient 5UPPOrt %ervices and community en8a8cment. Durin¥ thc y¢ar supporicr lyn Spriw complel¢d 8 372-mile a¢ross thc UK in aid of NSPKU. flnishing at the Royal Victorid Infimiary in Ncwcdsile where members of the PKU communiry gathcrd to celebrate his achievement. FINANCIAL REVIEW Flnanelal posltlon The net expenses resou¢5 for the year were £ 14,679 12024-. £35,641 income) detai15 Of which are shown OT] the Stamen¢ of Financial Activities. Prlnclpal fuTrdlng source5 The charity's income is derived primarily from donations. grani$ and communiiy fijndraising activities. These fidS support ihe charity's work in providing patscnl support 5crvi¢c5, 8dvoca¢y. ¢ommllnity en82gemcnt and rcsethrch Investment polley And objtctlves Th¢ Trustecs have the authority to invest fwid5 not immcdial¢ly required for charitablc purposcs in accordance with the charity's investmcnt policy and with due regard to risk. Page 3
THE NATIONAL SOCIETY FOR PHENYLKETONURIA {UNITED KINGDOM) LIMITED (REGISTERED NUMBER: (11256124) REPORT OF THE TRUSTEES for the year ended 31 October 2025 Fll¥AIYCIAL REVIEW Re5erv¢s pollcy The TneS recognise Ihe impotTancc of maintaining appropriaie r¢5erv¢s to ensure ihe financial stability of the charity and its abiliry to respond to unfore8¢¢D circumstances. Dwing th¢ year the Council of MaJ)agement undertook a detailed rewcw of the charitys reserves wlicy. The review considered thc Charity's financial p05iiion. the relative siabiliry of income and ¢)peJBting costs, and the opportunity to Lncrease thc impaei of the than.8 wot* through targ¢¢¢d investrnelll. Ai the y¢Jr end thc chjrity held rcsenfc5 of approximately £387,655, which is aiK)ve the previous guidelin¢ l¢v¢l of years, operating expenditurc (approximately £270,0(K)). Following this review. the Trustees agrecd to rcvisc the rescrves policy to tar8et rcscrY¢5 cquivalcnt to orte year of operating expenditure, currently Cstimated at approximatcly £140,000. The Truslces consider that maintaining r¢s¢rv¢s at this level pr()vides an appropriaie ba]ante between safeguarding the chan'ty's finan¢iul T¢sili¢nGe and endbling fiJnds be deployed in suppon of the charity's objective5. LJJrin8 di5CUssions the Council a150 considered options for the 5tructUT¢d use of resejwes above the ¢arg¢t Icv¢l, in¢luding allocating addilional filnding ovcr a dcflncd period to support stratcgic initiatives such as research. organisational dcvclopmeni and comrnunity ¢ng8gcm¢ni. Th¢ Council expressed a prcfcrence for an acc¢lcrated pro8fdTnmc of investment in the Lharity's activirie5 while coniinuing to monitor financial sustainability wefijlly. The level of reserve5 held by the ¢haTity is review¢d annually by the Tnjstees as part ot the chatity's financial pl8nning process FUTURE PLANS The Charity will continue to f(Kus on supportinB Lndividuals and families affected by PKU and improvin¥ long-tenn outcomes for (hose living with the condition. Key prioritlC5 ittclude implemeniin¥ th¢ charity's Tcscarch Strategy. slrengthening advocacy to improve access to treatments and seryi¢¢s, continuing develop dielary re50urc¢s ar supp)rt serviccs. and supporting community engagemeni activitie5 acr05S the UK. STRUCTURE. GOVERNANCE AND MANAGEMENT Gtsvernlnl dotument The National Sociery for Phenylketonuria {United Kingdornl Limited 18 a charitable company limited by gu8rorttee incorporated on 27 April 1976 and rc8isrered with the Charity Commi.48ion on 16 June 1977. The charity is govcrntd by it5 Mcmorandum and Artitles of Association. During the year thc Trustees undertook a review ol'the charity's Articles of Association to ensure they r¢mained consistent with modern company law and charity g0v¢rnce practLCC. Followins thi5 fcvLCW the Tjustees recommended aijopting reviscd Articles of Association. The propnsed chang¢s wcr¢ r¢port¢d to th¢ Charity Commissiofl and permission was granted for their adoption. On I I October the revised ArtiGles were fornially adopted by a resoluiion of th¢ mrnibers of the Chariry at an Extraordinary Gencral Mecting held in Cardiff. Re£rultment and xppolniment tsf new trustee8 Trustees. who are also directors for the purposes of company law. apptsinLed in Accordance with thc kniclc5 of A8SQClation. Tru51¢¢5 are typically drawn from ihe PKU community or from individuals with rclevant professional cxpertise. All the Trnstees are volunteer5. During the year the Council of Management undertook a recmitment pro¢c5S to identify additional tnjslees, recognising the value of 5tr¢ngthening the range of skills and expEricncc available to the charity. Applications were received froTr] tn¢mb¢r5 of the PKU community and candidates were interviewed by a pan¢1 of trustees. Thc Council considered th¢ importance of ensuring T¢pr¢s¢n¢atiQD from rO&S the PKU community and maintaining a balonce of cxpericnce within the board. New trUSeS receive itifonnaiion Bix)ut the chgrity's work and th¢ir rcsponsibilities as ttutees as part of thc induction prow. Org&ni5&tion815trlleture The charity is managed by the Council of Managcrncnl whosc members act as tnLskes and directors. The CouD¢iI is rcsponsible for governaTJce, sttategic direction and ovetssght of the charity'5 activitie5. The dlarity maintains a re$ter of conflicts of intcrcs¢ which is reviewed regularly by the CO¢11 of Management to ensurc tran5parcncy and good governance. Page 4
THE IYATIONAL SOCIETY FOR PHENYLKETONURL4 (UNITED KINGDOM) LIMITED (REGISTERED NUMBER: 111256124) REPORT OF THE TRUSTEES for tbe yegr ended 31 October 2025 STRUCTU GOVERNANCE AIYD MANAGEMENT Risk tnattagtment The TnteeS have con5idercd th¢ majoT risks to which the charity may b¢ pOSed and have established 5y8t¢ms and proc¢dur¢s to Tnitigat¢ these risks wh¢r¢ appropriat¢. Risks are reviewed periodically by the Council of Managemeut. Th¢ Twst¢¢s con$id¢r that appropriaw sysiems olld pro¢edure$ 8re in place to manage the principa] ri8ky facing thc chariry. REFERENCE A]¥D ADMtMSTRATtVE DETAILS Registered Company number 01256124 (England and W81¢5) Reglstered Charity tsurnber 273670 Regl$tered offlee St Andrews House 3 Tarlcton Otyice Park Wind¥ate Tar1en Preston Lanca5hir¢ PR4 6JF Trust A Thompsotj (resigned 1.3.261 D Noble- Nc5bitt (resied 12.4.25) J Cardy C Graham S L Noble-Nesbitt J Skidmore K Learoyd Mrs A Macdonald Dr E Vardy T Chhmiak C Cassidy Ms A Bagri Ms S J You5effi laFS)ointed 30.11.25) P McKrllar (wointed 30.11.25) Complly Seeretary K Learoyd Independent Exmlner H&yes & Co St Andrews House 3 farleton Office Park Windgate Tarleton PR4 6JF 26103126 Approved by order of the txjard of trtL$t$ on ........................ - and signed ¢)n its behalf by.. y Imai 28 2028 17 52 39 Gmt) K Learoyd. Ttustec Page 5
INDEPENDENT EXAMINER'S REPORT TO THE TRUSTEES OF THE NATIONAL SOCIETY FOR PHEI¥YLKETONURIA (UNITED KINGDOM) LIMITED Independent examlner's report to the trustees of The National Society for Phenylketonurla (United Klngdom) Llmited ('the Compally.) I reFd)rt to thc charity trustces on Tny examination of the accounts of the Company for the year ended 31 October 2025. ResponslbllAties basls of report A5 the charity's tnjslees of the Company land also its direclols foT the purposes of company lawl you are responsible for the preparation of the accounts in accordance with the requirements of the Companies Act 2006 {'th¢ 2006 Ac(). Having sattsfied myself that the accounts of the Company are not required to b¢ audil¢d und¢r Part 16 of thE 2006 Act and are eligible for indepelldeni examination, l Teport in respect of my examination of your charitys accounts as ¢anied out under Secrion 145 of the Chilles Act 2011 I'the 2011 Act'l. In canying out my ¢xamination I have followed the Dhrections given by thc Charity Commission unikr Section 145{51 (b) of ihe 2011 Aci. Independent examiner s statement I have completed my examination. I confirn) that no m&tters have come io my at¢¢ntioD in Ttell0 with the examination givin8 ME to believe.. counting re¢oTds were not kept in respect of the CornpHny as rquired by Sec(ion 386 of (he 2006 Act. or the Accounts do noi accord those records; or thc accounts do not comply with thc accountin8 requirements of Seciion 396 of the 2006 Act other than sny requirement thai th¢ accounts giv¢ a tN¢ and fair view wlu'ch 15 not a maU¢r considered as part of an independenl examination. or thc accounts hAve rtot been prepared itt accordance with the methods and principlc5 of th¢ Statcm¢nt of Recommended Practice for accountin8 and rtporting by charitie5 {applicablc to charitie5 prcpllring their accounts in accordance with the Financial Reporting Siandard applicable in the UK And R¢publi¢ of Ireland IFRS 102}). I have no concems and have come across no other matters in connection with the examination to which attention should be drawn in ihL8 report in order enable a proper understanding of the accounts to be reached. Anthony N Totham FCA. CTA Hayes & Co Si Andrews House 3 Tl¢ton 01¢¢ Park Windgate Tarlc(on PR4 6JF Date: ........... Page 6
THE NATIONAL SOCIETY FOR PHElKET0NUR1A (UNITED KINGDOM) LIMITED STATEMENT OF FINANCIAL ACTTVITIES for the ytar ended 31 October 2025 2025 Totsl funds 2024 Total Unr¢5tricted fund5 Restricted funds Notes INCOllfE AND ENDOWMENTS FROM DatiOnS artd I¢Ea¢i¢s 66,901 66,901 129,288 Ch#rltable #¢tivitie$ Membership and literary fxs Conference and events Vitaflo Sponsorship Lo8ixx Phamia 16.205 23,053 20.000 16.205 23,053 20.000 20,(KIO 16,490 20,372 18.000 20.(K)O Investmen( incom¢ Other income 10,888 2.860 10,888 2,860 11,621 6,739 Tot 139,907 20,(KA) 159,907 202.510 EXPENDITURE ON Charltable ictlvltles ConfererLCC and events Publications ReSth Dietitian's fccs and expenses Conf¢r¢nce and event cosis Insurance Athnini5tr4tion fe¢5 and expenses Meeting and Conference expenses Membership fees and sub8CriPlions Telephone Bank and Other Charges Trnvel P05t,stationery and advertising Deprcciation charge Website costs 30,971 15,444 16,134 35,229 42 2,124 43,854 30.971 15,444 32,384 35,229 42 2.124 43.854 59,661 18,703 3.115 29,269 10,250 2.157 45,751 167 1.747 50 552 1.23 1,827 2,640 97 1,263 7,854 97 1,263 7,854 2,640 2.684 2,640 2,684 Tot1 155,696 18,890 174,586 166,869 LYET INCOMEIIEXPEI¥DrruRE) (15,789) (14.679) 35.641 RECONCILIATION OF FUNDS Tothl fiu]d5 brought foTrvard 357,793 44,541 402,334 366,693 TOTAL FUNDS CARRIED FORWARD 342,004 45,651 387,655 402.334 CONTINUING OPERATIONS All income and expendibjre has arisen from continuing &ctiViti¢s. The t]05 fvmi part of these finallciai statelllellts Pag¢ 7
THE NATIONAL SOCIETY FOR PHENYLKETONUR IUNrrED KINGDOM) LTMrrED (REGISTERED NUMBER: 01256124) BALANCE SHEET 31 Oet(*ber 21125 2025 Total nds 2024 Total funds ur¢Stil¢ted fiu)ds R¢stricted fijnds Notcs FIXED A&SETS Intangible ass$ 1,046 1,046 3.686 CURREYT ASSETS Debtors Prq)ayments and a¢¢rned income Cash ai bank 924 750 352.961 924 750 398,612 480 1.306 408.104 45.651 354.635 45.651 400,286 409,890 CRLDI'foRS Amounts fallin8 due within onc ycar 10 {13,6771 (13,677) {11,242) NET CURRENT ASSETS 340,958 45.651 386,609 398,648 TOTAL ASSETS LESS CURRENT LIABILITIES 342,IM)4 45.651 387,655 402.334 NET ASSETS 342,(M)4 45,651 387.655 402,334 Unrestricted ndS Rcstriclcd funds 342.(X)4 45,651 357,793 44,541 TOTAL FifNDS 387,655 402,334 The charitable company is entitled to exemp¢ion from audit under S¢c¢ion 477 of the Companies Act 2006 for the year ended 31 October 2025. The mernber3 havc nol required ihe company to obtain an audit of its financial stst¢m¢nt8 for the y¢ar ¢nd¢d 31 October 2025 in accordance with Section 476 of the Comp8ni¢5 A¢t 2tKJ6. The ttustces acknowledge their reswn5ibili¢ies for ell5urin8 that the charitable COTnpany keeps accounting records that comply with S¢ctionJ 386 and 387 of (he Companic5 Aci 21y)6 and prcpariTJ8 financial statcmcnts which give a find fair view of the State of affairs of th¢ charitable cornpAny As ai the end of ¢8ch finart¢ial y¢ar and of its surplus or deficit for cach financial year in accordancc with th¢ requirements of Section5 394 and 395 and which othcnvise comply with the requirements of the Companic5 Act 2(M)6 relating to financial statements, 50 far as 8pplicabl¢ lo the rharitabl¢ rompany. {b) The notes forni part of these financial s(atements Page 8 contiDued...
THE NATIONAL SOCIETY FOR PHENYLKETONURIA (UNITED KJNGDOM) LtMITED (REGISTERED NUMBER: 01256124) BALANCE SHEET- eontinDed 31 October 2025 These financial statements have been prepared in accordance with the provisions applicable to chaTitsble companies subject to th¢ small companies regiyne. cial &tat¢rn¢nts were approY¢d by th¢ B(Krd of Tntstees and authorisrAI for issue on Y¥log8 . and were signed on its behalf by.. IMar2e, 2026 17-.52.39 GMT) K twoyd. TnLStee The tti)tr5 fonn part of these financial Stateents Page 9
THE NATIONAL SOCIETY FOR PHENYLKETONURIA {UN]TED KtNGIK)M) LIMITED NOTES TO THE FINANCIAL STATEMEprrs for the year ended 31 October 2025 ACCOUNTING POLICIES Bgs15 of prewdTlng the financlal statements The National Society for Phenylketonuria Iuniied Kingdom) Lirnited is incorporated charity rcgister¢d in England. In the event of the chatity being wound up. the liability in respeci of the guarantee is limited to £1 per mcmber of the chariry.The re&yistered office address is St Andrews House, 3 Tallen Office Park, Windgate. Tarl¢lon, Pr¢ston. Lanc&thire. PR4 6JF.The T]ature of the ch8riry'S operaiions and principal lctivitics are cxplained in ihe TNstees rcport. Thc financial stat¢m¢nts of the charitable ci)Tnpany. whiLh is a public benefit entity under FRS 102. have been prepared in accordance with the Charitie5 SORP IFRS102) 'A¢counting and Reporting by Charities.- Statcmcni of Rccommcnded PrACtiee applieable to charities preparing their accounts in aordanCe with the FirJanci41 Reporting Standard applicable in rhe UK and Republic of Ircland IFRS 102) leffcctive l January 2019),Financial Reporting Stdndard 102 'The Finatscial Reporting Standard applieable in the UK 8nd Republic of ITeland' and th¢ Companics Aci 20(hS. The financial statements have en ppar¢d und¢T the historieal cost convention. The rJncial statcmcnts are prepared on a goin8 concern basis under the hi51uriLal c051 conventiott. Thc financial stalements are prepared in sterling which 15 the functional CUrr¢n of Lhe charity and roundcd ro the nearest £. Thc significan¢ accowiting policcs applied in the pr&tiOn of th¢sc financial sMents arc Set oui below. These policies have been consistently applied io all yeArs. Income All income i& recognised in the Sratemeni of Financial Aciivitics once ihe charity has cntiilemellt to ihe fid6. it is probable that the income will be re1ved 2nd the amount can be measured reliably. Cirantq are receivablc in thc SOFA whcn receivable. When donor5 8pecify that grants given to Ihe charity musl be used in thc fvtur¢ finartcial ycars. the ineome is deferred until that yeor. Asseis &nd investments donated to ihe charity arc includcd as dnndtion income a( market value at thc time of rcccipt. No amouni is included in the financial Stslements for volunteer lime in linc with the SORP lfrs 102). Expendl¢ure Liabililics arc recognised As expendibjre as Soon as there 1$ a legal or cons1ntiVe obli8ation committin8 the ¢harity to that pendItur¢, it 15 probabl¢ that a transfer of economic benefits will be r¢quir¢d in s¢ttl¢ment and the amount of the obligotion can be measur¢d r¢liably. E.xp¢nditure is accounted for on an accwal.% basi5 and has becn ela5sifiEd undcr headings thai aggregate all cost relalcd to the ¢at¢gory. Whcrc c05tS Cannot be directly attributcd to parfi¢ular h¢adings they have been allocated to tIvItieS on & basis con51St¢nt with the u8e of resources. Charitable cxpcndilurc comprises those costs incurred by the charity on delivery of its tIvities and Services, including those costs of any indirect naLur¢ n¢c¢5Sary to support them. The ch&iry is not reSred for VAT. IntangIble assets Intangiblc &sscts are recorded at cos¢ and then amorti5¢d on a 5trai8ht line basis over their useful lives. The Useful Iivc5 of intan8iblc ets are as follows.. W¢bsite - 5 years Straight line Provision is mad¢ for any itnpairmcnt. Tangible fixed assets Depreciation is providcd at the following annual r&tes in onleT to WTit¢ off asset over iLS eIrnated use1 lifc. Computer equipment 330/1 on eost Thngible assets are initsally recorded cost. T#x2tion The charity is cxempt frorn corporation tax on i15 Ctwitable actiYitÉes. Page 10 eontinued...
THE NATIONAL SOCIETY FOR PHENVLKETONURIA (UMTED KINGDOM) LJMITED NOTES TO THE FINANCIAL STATEMENTS- Continued for the ye•r ended 31 October 2025 AccouiYfJNG POLICIES- continued Fund afcounllng Unresmetrd fiJnds can used in aecordance wth the charitsble objectives at the discretion of the tNstees. D¢signAt¢d ¢omprise of unr¢$tri¢t¢d fvrtds that Itave been s¢t ASLde by the trnstres for particular putposes. R&%tricted fvrtds cxn only be used for partieular restricted purposes within the objects of ihe charity. Re5triction5 aiisc when spccified by the donor or when ndS are raised for particular restricted purp¢)scs.Thc cosi of raising and adminLSterinB su¢h funds are charged asainst thc specifLC fund. Further explanation of the nature and PUTwse of each fund is included in the notrs to the financial 5tarements. Goln% coneern The knjsiees assess whether the use of goinE concem is appropriate i.e. wheiher there Hre sny material Uncertainti rcla¢¢d ¢0 cvcnts or conditi(m$ iha¢ may cast significant doubt on the ability of the charity 10 coniinue as a going concettj. The tnjstees make this assessment in respeci of a period of aL1¢&st one year from the dale of auih0ri5ation for issve of the financial 5talem¢nls and have concludcd rhai the Charity has adcqualc resources to continue in operdiional existence for the foreseeable future and th¢rc 4w¢ no ma¢rial unoertdinlies aboui the charity's ability 10 continue us a 8oin8 Concern, thus they coniinue adopi the going conccm ba515 of gccounLin¥ in preparing the financial 5talem¢nt$. CRITICAL ACCOUNTING JUDGEMENTS AND KEY SOURCES OF ESTIK4TION UiYCERTAINTY There knve been no si8nificAttt jud8ements made in the process of preparing the financial statements. There have been no kcy assumptions concernin¥ thc future and other key sources of estimation unccrtaiftry at the rep()rting dale ih&t hav¢ a Significant risk of causing a m&ierial adjustsnenr to the canying amounts of assets and liabilities within Lh¢ next fLnMn¢ial year. INVESTMENT INCVME 2025 2024 Dcposit account inter¢5t 10.8811 NET INCol[ExPENDITuRE) Net incomell¢xpendi¢ur¢) 15 slated after thargin{CredItlng).' 2025 2024 Compuler software gmortis&tion 2.640 2,640 Pagell continued..
THE NATIONAL SOCIETY FOR PHENYLKETONURIA {UNITED KtNGDOM) LIMITED NOTES TO THE FINANCIAL STATEMENTS- continued for the yr ended 31 October 2025 TRUSTEES. REMUNERATION AND BENEFTTS There were no ttwtee5' rernuneration or other benefits for the year ended 31 October 2025 nor for the ye4r cnded 31 October 2024. Ttt5, exp¢n5ts Th¢r¢ were no tsusS, ¢xp¢ns¢s paid for th¢ y¢ar ended 31 October 2025 nor for the year ended 31 October 2024. COMPARATIVES FOR THE sTATElENT OF FINANCIAL ACTIVITIES Unrestiicted Restricted Total INCOME AND ENDOWMENTS FROM Dot)aiions and legacies 109,288 20.(K)O 129.288 C.barlthble actlwltle5 Mernbership and literary fees Confer¢n¢c and events Viraflo Sponsorship 16,490 20.372 18,IMM) 16.490 20.372 18.000 InY¢slm¢nt Inrne Other income 6,739 6,739 Tot*1 182,510 20,000 202,510 EXPENDITURE ON Charlt#ble aetlvltl COnfeT¢yc and events lblICatI1)nS Rs5e4Ch Dietitian's fees 4nd expenses Iu[anCe Administration fees and expenses Meeting and Conference expenses Membership f¢¢s and subscriptions Telepbone Bank and Other charges Travel Post,stationery and Advertising Depreciation charge 59.661 18,703 3,115 29.269 2,157 38,751 167 1,747 50 552 1,230 1,827 59,661 18,703 3.115 29,269 2.157 45,751 167 1.747 50 552 1,230 1.827 2,640 7.O¢KJ 2.640 Total 157,229 9,640 166,869 I¥ET INCOME 25,281 10,360 35.641 RECONCILIATION OF FUNDS Tothl fidS brought forward 332,512 34.181 366,693 T(YfAL FUNDS CARRIED FORWARD 357,793 44.541 402.334 PagE 12 continued..
THE NATIONAL SOCIETY FOR PHENYLKETONURIA (UNrrED KtNGDOMI LtMrrED NOTES TO THE FINANCIAL sTATEMEs- for the yeAY ended 31 October 2025 INTANGIBLE FIXED ASSETS Computer s0(iware COST At l Nov¢mb¢r 2024 and 31 thiob¢r 2025 13.200 AMORTISATION At l November 2024 Charg¢ for year 9,514 Ai 31 O¢lober 2025 12,154 NET BOOK VALUE Ai 31 October 2025 1,046 Ai 31 October 2024 3,686 TANGIBLE FIXED ASSETS Computer equipment COST A¢ l November 2024 and 31 October 2025 430 DEPRECIATION At l November 2024 and 31 O¢iober 2025 430 NET BOOK VALU At 31 (ktob¢T 2025 At 31 (ktobcr 2024 DEBTORS: AMOUNTS FALLING DUE AFTER MORE THAN ONE YEAR 2025 2024 Trade debtors 924 480 P¥ge 13 continue&..
THE NATIONAL SOCIETY FOR PHENYLKETONURIA {UNJTED KINGDOM) LIMITED NOTES TO THE FINANCIAL STATEMENTS- continued for the year ended 31 October 2025 io. CREDITORS.. AMOUNfs FALLING DUE WITHIN ONE YEAR 2025 2024 Trade creditors A¢cTu¢d exp¢rc5 7.594 6.083 9.647 1,595 13,677 11,242 MOVEMENT IN FUNDS Net At 1.11.24 movement in fimds Ai 31.10.25 UnTe5tr1¢tcd General nd NSPKU Gran¢ and r&8carch fund 337,793 20,(MMI (15.789) 322,004 20,000 357,793 (15,789) 342,004 Re•tri¢ted funds Research Fund Website Mr & Mrs Ch&thAm Tobemiore F(x)tball Club Rese8rth in PKU Reaching oui fijnd Educaiion R¢search Grant 16,211 5,420 410 2,5(M) 10.O(K) 10,o(K) 16,211 2,780 410 1,250 5,0(M) I0,1) 10,IMK) (2,640) (1,250) (5.000) 10.000 44,541 45.651 TOTAL FUNDS 402,334 114,679) 387,655 Net tnovement in fimd5, included in the &EK)ve are follows.. IncominB r¢50urce5 Resources expended Mov¢m¢nt in funds Unrestrl¢ted funds General fijnd 139.9)7 1155,696) (15.789) Restrl¢ted fvnd8 Web8lte TOb¢nnO Football Club Rr%arch in PKU Education R¢5wch Grant (2.640) (1.250) (S,0() (l0,{K) (2.640) (1,250) {5,000) 10,0 20,000 20.000 (18,890) TOTAL FUNDS 159.907 (174,586) 114,679) Page 14 continued...
THE NATIONAL SOCIETY FOR PHENYLKETONURIA (LNTED KTNGDOM) LJiiirrED NOTES TO THE FINANCIAL STATEMENTS- contiputd for the year ended 31 October 2025 MOVEMENT IN FUNDS- continued Comparatlves for movement in fundi Net moY¢rn¢nt in ndS At 1.11.23 At 31.10.24 Unrestricted funds Genera5 fvnd NSPKU Grant and research fimd 312,512 20.0(K) 25.281 337,793 20,000 332.512 25,281 357,793 Restrlcted lunds Research Fund Website Mr & Mrs Chaiham TobeTTlloTe Footb411 Club Rc5¢prch in PKU Reaching out fund 16.211 15,060 410 2.5(Kl 16,211 5,420 410 2,5 10,(KK) 10,( (9,640) 10.O(K) 10,(KK) 34,181 10,360 44,541 TOTAL FUNDS 366,693 35,641 402.334 Comparative nct movement in fijnds, included in the above are as follows.. Incoming resources Rcsources expended Movemeni in ndS Unroitrleted fuDds General fimd 182.510 (157,229) 25,281 Regtrlcted fvndi Website R¢s¢arch in PKU Reaching out fijnd 19,fAO) 19,6401 10.ooo i o,ooo 10.000 i 0,000 20.000 19,640) 10,360 TOTAL FUNDS 202,510 (166,869) 35,641 Page15 continued...
THE IYAT10Tr4AL SOCIETY FOR PHENYLKrfoNiIRIA (UNITED KINGDOM) LtMJTED NOTES TO THE FINAI¥CIAL STATEMENTS- eontlnued for the year ended 31 October 21125 12. RELATED PARTY DISCLOSURES There were no related party transactions for the year ended 31 October 2025. Page16