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2025-12-31-accounts

, ADELPHI GENETICS FORUM Annual report and unaudlt•d Flnan¢lal Statoments for tho yaar and￿ 31 DKember 2025 Charfty Reglstrallon Number- 209258 Company Number- 1x1217533 JCS Accountants Limited 5 Robin Hood Lan• Sutton Surrey SM12SW

Adelphl Genot1￿ Forum (Limitod by Guarantea) FlnancSal Statements for the year •nded 31 Decornbor 2025 Cont•nt• Pago Trustees. rewt 1-3 Report of the Independent Examiner Statement of Flnanaal Adivi Balan¢* Sheet Notes to th8 financial stateM￿ts 7-12

Adelphl Genetics Fonmn Reference and administrative infornw Trust• Prclessor Don Dorwi Dr Rosèmary Ekng Tr•asur•r Ubfadan Afchlvlt Mr Robert Johnston Dr Hel8n Mk1dl•ton-Prè Coun¢ll Dr E18na Boutrwkw Iroswjned 18.IX.2025) Dr Geor￿ BLwghèl PTofesY Shir Hryjg Or Ralph Ltithn¥on PTrAessor Annaka Lucas￿D Prolessor C.G. N￿￿45 Masd0vTa￿or Dr P8n#9KAis SWI￿0118 Profess￿ Dallas Sw•lbw18pw'ntwJ 18.06.20251 Prirfossorveronhx van HeynknJ•n Or Sarah Q•n•r•l S•cY•l AddrM• •nd R•*Y•d Ollk• SY118 1PE Mirlam H￿ks￿ CTA FCA JCS A￿SUn￿niS Um4ted 5 Rob￿ Hoc•J Lan• Surrey SM12SW CCLA Furnl M￿n￿￿15 1 Angel ia L(m¢kn EC4R 3AB Bank•rn Uwls Bank Ltd 71 EC2V 6EN R•gl•t•r•d Ch•rlty Nwnb•r C¢Jmpary 14urnb•r (M)217533

Adelphl Gonetlcs Forum Trustees Report The members of the Council of Management submit ttir rep(￿t and the financial ststements of the Forum for the year ended 31 December 2025. Structurn. Governance and Alanagement The Adelphi Genetics Forum (the Forum). was 8s a ccmpany limited by guarantee on the 15th November 1926, and was registered the Chartty Commission in 1960 with whom its registration number is 209258. The goveming d0￿ment of the Forum dated 24 May. 1961 was r8plac8d in 2024 ty an am8nded Artides of Asscrfyation vthich was adopted by a special resolution P8ssed 8t a Gener81 Meeting of the members held on 20 March. 2024. On 21 September 2021 the Galton Institute changed its name to the Adelphi Genetics Forum. Durin9 the year our General Secretary retir￿1 and Mrs Rulh Matthews was appoint&J in her the. Objecllves and Activities The Forum exists to promot8 publTrc und6rstanding of Ihe 8(xen(% of human hèredity,. its historical development and its impact on cognate disciplines. Th8 principal means of achieving these objectives are the holding of an annual conferenc8 and a biennial teachers conferen￿, the publication of the Adelphi Review, sponsorship of relevant o)nferenc4s, publication of booklets on topical themes in the ts'osocial sciences. wblication of occasional to)ks. trav61 bursaries for r8S8arch students. small grants cOnfW￿ organisers. suppct for a PhD st￿lantshiP and the malntenance of a website. Publlc Benefft Statement When planning the activilies the T￿￿188$ have had regard to the Charity commi￿on'8 Guldan on the publlc benefit of the Forum's activities in particular the 8dvancem8nt of publlc education in appropriate areas of knthvledge. Conferences and Publkatlons During the year the Forum organlsed a large ojnference with a number of guest speakers at the Royal Society on the 23 October 2025. entitled Populat￿ Genomic Screening - Exploring its Complexitiès. The Forum published tVKJ issues of th8 Adelphi Rewew durlng the yèar. Grant A￿T￿3 The Forum makes small grants kn ¢Mferences and VK)rkslh)ps and it cu￿entlY budgets £8.000 for such grants each year. Up to iwo Junior Scientist Travel Felkjvships (each being £750 in total) ar8 also available and are COwSP)nsored wilh the Genetics Society. The availability of grants is advertlsed on the Forum's website. Each application is r8Vi8wed by a committee of Trustees and, subject to th8 avallabilty of furKlirwJ, appmved If the prq)osed conferenc8 is exFeCted to further the Forum's aims. Page 1

Adelphl Gonotlcs Forum Trustees ((xrfinued) Grant Awards (continued) The Forum is supporting a three year PhD studentshlp atthe Departrnent of Genetics. Evolution and Environment at Universty CrAlege London on a tow"c related to the Forum's aims. This is entltled 'Removing the population ￿[Kept fr(Mn evolutionary genetics, and r6 supwrfised by Professor Mark Thomas, Dr Adrian fimp80n and Dr Adwn Rutherfixd. In tho course of the year the folknw#￿ grants were made:_ Progress Educational TNSL. Virtual educational event about MitC￿h0ndria1 donation Int8mation81 History of Eugenics Conference at Oxford Brookes Universty Centre for Humanities The Polish Society for Human and Evolutlcn Studles for C<)nferen(x: Humans in Evolutionary Perspective Francis Crbck Institu￿. HAAM Sum￿￿T School 2025- vlrtual Progr8ss Educational Trust: What Genomics Mean for Fertilty Tr88tment European Molecular Biology Laboratory 2P EMBL PhD Sympw)sium'. Shaping Tomofft)w.' sc￿nCe with lon￿tenn impad UCL PhD student award to cover fees and expenses IncJJrr8d h 2025 Removing th8 population concept frtvn ovc1￿l0nary ggnetics 1.000 1,IX)O 1.000 58.037 Travel Bursarles The Forum vlll award up to one travel grant P8r year for (xrtstandlFVJ Postdoctoral resear¢hers. Funding viill be up to £6,000 per year. Future Developments The Forum will hold their Biennial Teachers Conference on 26 June 2026 at the Nowgen Centre in Manchester. The theme of the tsiks will b8 Further Advances in Genetics. The Forum plans to hold its annual rA)nference at the Royal Society in the autumn on 22 October 2026. This will be entitled Complexty of Neural Function- the brnin in charge. The Forum will publlsh further issues of ts Adelphi Review In the year. Flnan¢lal Revlew The net expenditure for the year before gains and losses on investments was (£22,563) and th8 Géneral Fund at 31 December 2025 amounted to £4.279,448 compared to £4,506,770 at 31 December 2024. Realised and unrealised losses of £204,759 arose because ofthe change In market value of th8 investments that arè rnanag8d by th8 CCLA Fund Managws. Res•rves polky The Forum's pclicy is to maintain sufficient reserves to ensure that it is able to meet its running costs from the retum on its investments without retying on either subscnptions or extemal fund-raising. Risk assessment The Council has assessed the risks to which tho F(xum is exwsed and is satisfied that Systems in place are adequate to mitigate those risks that would threaten the long-term survival of the F¢)rum. The Council is content that oth8r risks shwkj be a￿￿pted because the cost of mitigating them w¢)uld be unacceptable. Page 2

Adelphi G•n•tlu Forum TTUYtees Report Icontinuèfj New Txustees are generally Jdenb)W •KI proposed by extsb.ng Tn￿te Us• of Volunlws Thg Fotum does not prim8rity out its Jdivithes throuph ts wctured use of volunteers Some Trustees contrI￿e • l•rge amowrt of time to the FoTum in addItic￿ to they duties as Trustaes Statom•nt ol TrUst￿'S R•sponslbllhl•s Compony knv requires Trustees lo prep•r• fin•n¢i•l stalemwts for each yo•r tiich give a tnje and tsir view of the aff8iTS of the company ol its financ￿1 posrtion al the year end In wapaiing the financtal 81atsm•nts th• TNstees shoukj fofthi b•st pradic• and sec SUrtab￿ accountulg poliues and appty them consistenlty They shoukl make judgemerts and ost5mal8s th81 ar8 rèasonable and prudent and pmpare the financi81 $18tements L)n ¥ gOi￿a ¢on¢em ba$M unle¥$ rt L• inappropriate to presume that the charity wim contsnue KJ operation. The Trustees •re wponslbkn for k•¢pJng rKords which ¢Yisdc4e V•llh rtr8son8bL occuracy the financi￿ posibon ol the c¢)mp•rry and whKh eTkablp them to ensure that the fingnual statements compty with the Companies Acl 200& The Trustees af& 81$0 responsib￿ lor safeguardNw the assets of the charty and hence lor I8￿ng reaonable for the prevention and dotechon offrALY ano othei Irrfjgul¥ttl•s Sm•ll Cpmp•ny This Teport has t4•n prepor•d In a¢¢ordan¢e wlth wovislw •ppIl￿b￿ to comp8nl•i iubJ•ot lo th¢ small companjes wme wthin Part 15 01 the CoM￿nieS Act 2006 On beha￿ ofthe Board, Andrew P Reo¢. Honorary Tr•a8ur•r 18 Maich 2026 Page 3

Adelphi Genetles Forum Report of the Independent Examiners for the year ended 31 December 2025 Independent examinorfs report to the trustgos of Adelphi Genetlcs Forum I report to the charity ITUStees on my examination of the accounts of the Adelphi Genetics Forum for the year ended 31 December 2025 set out on pages 5 to 12. ResponslbllFtle$ and basls of report As the charrty's trustees you are responsible for the preparation of the accounts in accordance wrth the requirements of the Companies Act 2006 (Ihe 2006 Art}. Havin9 sati$ffièd myself that the accounts of the Company are not required to be audited under Part 16 of the 2006 Act and are e1￿ible for independent examination, I report In respect of my examination of your ¢harity's accounts as carried out under section 145 of the Chanles Act 2011 1.the 2011 Acl'l. In carrying out my examinatron I have followed the directions given by the Chanty Commission under section 14515}Ib) of the 2011 Act. Independenl oxaminefs statement I have completed my examinatson. I confim that no material matters have come to my attention in connection with the examination giving me cause lo beI￿ve that In any material respect.. accounting ￿CordS were not kerrt in respect of the Company as required by section 386 of the 2006 Act,. or the accounts do nol accord wth those records. or the accounts do not comply with a¢¢ounting requirements of sertion 396 of Ihe 2006 Act other than any requirement that the accounts grve a 'lrue and fair view. which is not a matter considered as part of an independent exarnination,. or the accounts have not been prèpared in accordance vAth the methods and piinciples of Accounting and Reporting by Charrtie$'. Statement of Recommended Pra¢ti¢e applicable to charities preparing thwr a¢counts in accordance wrth the Financial Reporting Standard applicable in the UK and the Republic of Ireland IFRS 1021. I have no concerft$ and have come across no other matters in connection the examination lo wh￿h attention should be drawn in this report in order to enable a proper understsnding of the accounts to be reached. Miriam Hickson CTA FCA JCS A¢¢ountants Limited 5 Robin Hood Lane SLffton Sufrey SM1 2SW Date.. 26 mcwcLx Zoa Page 4

Adelphi Genotlcs F(Kum Statement of financial adivities for the year erthd 31 D￿mber 2025 (incorporating the & expenditure account) No¢• 2025 2024 Incomo and 8ndowm￿Its from: Charitable activities Subscriptions 448 Invostmonts Investment incm Deposit interest 118.161 7.881 114.689 9.714 Other incom8 Total Incomo 134 851 IIIL97 Expendlturo On: Raising funds Cost of Ad8lphl Revlew Cost ryof Annual Conferenc8 Cost of Teachers Conferenco 4.074 32,339 2.427 23.251 Charlt8bl@ actlwtios Grants For small conferenc88 PhD grant Admlnistrauon costs Governance costs 6,300 58.037 49,940 5,500 29,953 53,194 Total éxpondltura 124 Net Incomellexpendfture) b•foro galnsl(108808) (22.563> Net galnsl(losses) on Inv8Stm8nts N•t movement In funds (227.322) 110,455 Fund balances brought f0Th￿rd at 1 January 2025 77 4396315 Fund balances carrted forward at 31 Decemb8r 2025 Page 5

Addphi Genètics Forum Bnce Sheét #s at 31 DecmbeT 2025 Company number 00217533 hlot• 2025 2024 Fix¥d As•ts TaTrglb￿ as Inv8stments- unlthd 122.980 978. 4 101. 125.327 4.183.14 4 308 475 Debtors Cash ot bank and In hand InveS￿entS- ijeposil accoLmt 15.002 17.113 193 565 225.680 15.418 21,043 Cury•nt labS1Stl•• Creditors amtyJnts f•iling d wlthln one year 217.984 10 47. 19. Net cuvrnnl •M•ts 178 Tot•1 N•t AAs• Charlty lund• General Funtt 11 For the yfrar ended 31 December 2025 the company wa$ entifjed to exemptNI from undèr 8ectth 477 olthe ComFonies Acl 20Cfj re18ting lo small cornpanjes. Th• m•ml)•Ts n(A r￿[￿red the c¢)mpany lo obta>n an audil of 518 finon¢laJ st•lem•nl• for the period in ques1￿￿ ￿ 8ccord8nce wilh sg¢bon 476 of the Companies A(4 2(K16 Th• Trustees a¢know thelr r68ponsib￿llw4 lor c￿￿n9 wth Ihe r•quN•m•nts d tho Comp8nles Aa2008wtih re¥pedlo wxourlNvJ ￿C￿d$ ¥nd otfinancial stalam6nts. These financi￿ th1gm•rrt3 have wepafed in •cc¢thnce vAlh Ihe prow0￿ WIbc￿fj lo comp8nlas sutyeci lo tho smdl comparues Tegim• Thw financial 81ater￿rrt$ *ve 8wo¥ed by the Trustees on 18 March 2028 Andr8w P Read Honorary Trèasurer 18 March 2026 The no188 on pages 7 to 12 form part Of1￿ ar£0￿. Page 8

Adelphl Genetics Forum Notes to the financial statements for the year end&1 31 D￿nber 2025 1 Accountlng pollcles Adelphi Genet￿￿ Forum is a company limited by guarantee. and a registered tharlty. Th8 register8d office is at 19 North￿IdS PrW Northfi8kls. London. SW18 1PE. Basis of preparation The financial statements have been prepared in acCQrdan￿ wilh the Charities SORP 2019 (FRS102) - Acrx)unting and Rep(Kting by Charities: Stat￿nant of Recommended Practice and appllcable United lQngdom law and accounting standards. The Forum meets the definilion of a public b8nefft entity under FRS 102. The finanaal statements have been prepared under the historical cost convents'on, with tha exception of investrnents which are induded at market value. and in accordance with applicable accounting standards. Golng conrAm Thè Counal of Managemént cx)nsders that there we no material w¥xrtain￿s ab(xrt lh8 charity's abilty to continue as a going conc8m. Incom• All income is recA)gnised once the charity has entillement to the income, rt Is probable that the income will be r8c8iv8d and the amount of income receivable can be measured with sufficienl accuracy. Expendlture Llabililies are recognls8d as resources expendad as soon as there is an obligatlon committing the charity to the expendilure. All 8xp8ndliur8 is accounted for on an accruals basis. Grants payable are payments made to thkd parties In the lutheranc* of the charltabl8 obj8ctives of the Forum and are authorwd by the Council of Management. Uncondi￿n81 grants are re￿gnised once the reclplent has boen not1￿ of the grant award. Charitable support costs have not been allocated to speufic 8xperKliiure. A large proportlon of these costs are aLrounted for by work gtven freety by the Trust88s. To attempt to cost this would be unecorK)rnic to any benefit Obtai￿d. Governance costs Govemance costs are those costs assoLiated wlth mèeting the constftutlonal and statutcry requirements of the charity arKI indude fees of the Ir)dependent Examiner and costs linked lo the strateglc management of the charty. These have been 8lk)cated directly to charitable expenditure. Galns and lossos on investmrbts Realised gains and losses in the ststement of finandal act]vibes represent gains and lows by the Fowm on investrnents sold durin9 the year. Unrealised gains and losses in the statement of financial activiknes represent the net increase and decrease in the market value of the Forum's investments since the previous balance st￿t dat8 or the date acquired. If later. Page 7

Adelphi Genetics Fofum Notes to the financial statements for the year end&J 31 D8C8mber 2025 1 Accountlng polldes (eonllnued) Fund accountlng All income and expenditure is taken to Ihe General Fund. The Fwm has no designated or r8strictsd purpos8 funds. Restricted fijnds are those subject to speofic In￿ts, which may be decla￿1 by the donor or with their authority. The charity has no restrict8d funds at this time. Tanglble flxed assots and depreclatlon Freehold land is not depreciated. Depreciath)n is cak]Jlat8d to write down thr ass8ts to their residual values at the end of their antripated us8ful lives at ts folbwlng rates and bases.. Comput8r equipmwrt- 20% straight line Office furnitu￿ and other equipm8nt- 10% on r￿lucIn9 balance Freehokj buildiros- 2% straight line Investments Investments are statsd at market value as at the year and. The Adelphi Genetics Fomm rents out part of the premises it owns and ocupies. However, as It is mix8d use propety where investment component of the propety cannot be reliably measured. owing to its integration wtlh the ground floor vthich the Forum occupies. it is accounted for under at cosL Cash al bank and In hand Cash at bank and in hand includes cash and sTrh)rt-temi hwhly Ibauid inveslments with a short maturty of threa months or less frr*n the date of acquisits'on or openlng of the deposlt or slmilar account. Credltors and provlslons Creditors and provlslons are re(x)gnised kn the charlty has a present obllgation arising from a past event that will pyobably result in th8 transfer of funds to 8 third party and the amount due to settle the obligation be measured or estimaled reliably. Creditors are recognised at their settlement amount. Provisions have been calculated at the best estimate of the settlement amount. Flnanclal Inslrumonts Th8 Charity only has financial assets and financxal liabilitses of a kind that qualfy as basic financial Instruments. Basic financial instruments ¥e initialty recognised at the tfdnsaction value and subsequently measured at their setuemont Val￿ wÉth the exception of bank 108ns which are subsequently measured at anKJrtised cost using the effective interest method. Page 8

Adelphl Gonetlcs Fonvn Notes to the finan(aal statements for the year ended 31 D￿mber 2025 2 Adminlstratlon costs 2025 2024 Salary Costs Water Rates and service charge Light and heat Telephone and postage Printing and stationery Advertising and mthtirvJ Insurance 40.416 258 2.888 427 1.081 907 2.433 1,989 37.858 218 2.778 1,675 977 3,993 1.973 1.920 k !! Website arKI ￿rnwter expen8e8 COU￿11 meetings Subscriptionslmemberslups Bank charges Repairs and maintenance Entertaining Miscellaneous expgnses Depreciation Recharged to Related Party 1.302 1,037 740 45 2.898 2,312 740 23 35 217 3,523 469 3.047 The Trustees have agreed that the Related Party. the Adelphi Artemis TTUSt. should bear 12.5% of applicable support costs that are bome by the Forurn as it shares the support facilities. The method of allocation Is on a tlme us•J basis. 3 Governance costs 2025 2024 Travel, subsistence and room hire Accountlng faes Independent examination fee Legal costs 1.274 3.877 1.541 742 3,870 1,440 858 4 Salary costs 2025 Salary Nats"onal Insuran EmFloyerfs alh)wan 40,416 3,916 (3.916) 37,858 4,034 (4.034) Amount transferred to Related Pafty Number of em￿oYeeS 1 (2024: 1) Page 9

Adelphi Genetics Forum Notes to the finanGial statements the year ended 31 December 2025 5 Transactions wlth Trustees 2025 2024 Travel and subsistence expenses reimbursed The number of Trustees reimbursed was 8 {2024'. 9). The Trustees do not rec8ive any remUr￿at10n but may be reimbursèd for out of pocket expenses incurred in the perf￿ne* of Forum duties. 6 Tanglble flxod assots Freehold Property Flxtures FSttlngs Total Cost Al 1st January 2025 Additions for the yè8r 152.375 28,410 180,785 699 At 31 st December 2025 152 Deproclatlon At 1 st January 2025 Chargè for the year 27,047 28,410 55,457 At 31st December 2025 41 Nét book value At 31 st December 2025 At 31st 08¢ember 2024 Page 10

Adelphl Genetlcs Forum Notes to the financial statements for the year ended 31 Decwnber 2025 7 Flxod assets: InvestThnts Unllstad Inveslments 2025 2024 Market value at 1 January 2025 Transfers from current assets (Disposals) Realised gainsl(lossesl Net unrealised investrnenl (losseslgains) Market value at 31 December 2025 4,183,148 3,982.197 100,000 Historical cost at 31 Decernber 2025 8 Déblors 2025 2024 Artemis Adelphi Trust other debtors prepayments Accrued income - PLS Accrued income 7,134 7,946 6,712 728 32 9 Cash at bank and In hand 2025 2024 Lloyds: Current Account Paypal 17.113 21,043 10 Crodltorn 2025 2024 Grant commllments Other creditors and a(LYuals 39.321 13,891 Page11

Adelphl Genetlcs Forum Notes to the ffinancial statements for the year ended 31 Der2mtw 2025 11 General fund 2025 2024 Balance at 1 January 2025 Net movement in funds Balance at 31 December 2025 4.506,770 4.396,315 110455 4 506 770 12 Rolatsd party and rèlat￿ party transactlons The Forum has overall control over and uttimate tesKM)nsibility for the assets of the Adelphi Artemis Tnjst (the Trust). The latter trust was established i)n 17 July 1978 to admlnlstèr the assets of The Soaety for C￿strUCtIve Birth Control Limited whith was 11quidat￿l at that time. The Trust Deed provides that the incorne arKI assets of the Trust be applied to -preserv8 and protect the physical and mentsl health of people. particularty but not only those from Frt￿er communities by assisling in the provision of fertilty control and other measur8S to improve reproductive and sexual health." The Forum provldes s￿retaria1 and administraove servicth to the Trust for which it is reimbursed at costs. The total amount of suth servKes in the year was £7.134 (2024: £7.946). At the year end the Trust owed the Forum £7.134 (2024. £7.946). The Trust's net expenditure for the year was £35.089 (2024: Nel incom8 £25,262) including £34,995 of unrealised investment losses {2024: £16.150 of unre8llsed Investrnent galns), net assets at the year end wer8 £745,462 (2024: £780.551). As pemiitted by Charities SORP 2019 {FRS 1021. consolhlat8d accounts are not prepared as the Forum is a company and th8 Combined income ofthe linked ch8rrties is below the audit threshold. Transactlons vAth Trustees are detailed in NLXe 5. There were no other r8lat8d paty tr8nsactM)ns. Page 12

Addphl Artomls Tn¥t 31 DoGwnt￿ 2025 Reglstargd Charfty No. 209258-1 5 Robln Hood Sutton Surroy SM12SW

Flnandal stat•M￿ forth• yoar en 31 Docomber 2025 Administrative inf(ffiialk)n Roport of the Trustees Statement of Financ￿ Aclivibes Balance sheet Notes to the financlal ststeme 2-3

Adglphl Artomls Trust Reference and administrth wrf(¥rn Reglstered Offlce 19 Northfi8lds Prospe(i L¢¥th. SW18 1PE Investmert advlsers CCLA Fund Manager5 1 Angel Lane London EC4R 3AB Bankars Lloyds Bank Ltd 70-71 Cheapside Loftdon EC2V 6EN Trustees The Council crf Alelphl G8netKs Ftyum

Adelphl Artemis Trust Report of the Trustees kythe year 31 D8￿mber 2025 The members of the Trust ￿bMit Ih8ir r8pc¥t WMI the fin￿Cla slat￿￿ts of the Tnjst for the year ended 31 December 2025. Lggal and administratfve det•ls The Adelphi knmis TnBt (the Tru8t) is 8 regtst￿ed (arity and a linked dnty of the Adelphi Genetics Forum (th8 F¢yurn) whith. on 21 August 1978, IA)tsined re￿n￿"on as a Trust Corp)r8tion (Article 8a) in order to accArk responsibilty for this rela￿ charity. Th8 Trusys cyiginal endov•wn&nt (>Jmpnsed the liquidated a53ets of the ScKiety for C¢m$trudi￿ Birih Control Limiied ttywh Tknich the Fonjm haj, for a period of ￿ghteen years, managed the Mwie StO￿s MeM￿la1 C￿n￿. As a resutt of the many thanges In the last four decades in socbal altiiudes, s(#xk￿norn￿ dr(xJmstancw reprcrflu¢Uve t&thnologles and medical knowledge and waclK, the Forum's Cwndl ￿lder&I thal the Ilme had comè to widen the objectives of Ihe Tntst to enabl8 it to play a more effeLve and wKler role in thg very drfferenl f))ndltlons of thg twenty frst century. vthilst maintain1￿j much of tho spirTt the ￿l91n81 Trust Deed dated 17 July 1978. Th8 Galton Irtstitute Artemis Trust d¥grwl rt8 name lo the Adel￿1 Artembs Tnjst on 18 February 2022. The Forum's Council comprw the Board of Tr￿tea3 d this Inkwj ￿rity and. by (xdor of the Coundl (though not by Trust Deed) is (xMnmTited to speNlirwJ only the acxumulated i￿￿Me frcrfn th8 Fund. The Forum F￿vide8 se(Tetarial and admintstratNe Serv￿ to the Trt￿f(¥ whith it is reimbursed at o)st. The Trusleas ofthaTrusl oynprlsethe Offiw5 ofthe F￿￿M and the C(xJncai m￿be1$ as 51sted In the actounls Recruitmentand app<¥ntment of TnMtees New Trustees are generally idenlffied and tA￿P09¢d by existing Tnt86s. New Trusto8s are glven the TN8t Deed cxrtllnlng their respW￿Sib1l￿tI88. of Voluntoern The Trust does not pl¥na￿ly caffy (Mjt its acts'vilies through lh6 strucbJr&J us6 of volunteers. TPwe are no regular volunt8er8 othor than th& Trust888. S(¥n8 Tnkn88 cffitriLwJt8 a Ivgo amwnt of tlme to the Tnjst in add11￿ to their duties as Trustees. Councal has assessed the rlsks to wNch th8 TrL￿1 Is expos&d and is Satrrf￿d that Syats￿ p4aco are adequato lo mitigate those rlsks thatW¢￿Id threaten th8 lontemi survival ofThe Adelphi Genetics Forum. Council is content that other risks st￿Uld be accepted b￿￿use the (xJ5t d mibgabng them woutd be unacceptable. The Tn￿t'S policy is to maintsln suffic4ent reseprfes to ensure that il able to meet Its nmning ct6ts frThn th& return on rts Investsnents withjrt retysFVJ on eiltw s￿￿1p1￿C￿lS Ix extemal fiJrMknising. Oblectlves and Acllvltle8 The oblects of the Trust are: To preserve and rKotect the pty￿Cal arKI mental of per. rI1￿lartY trArt not only those from poorer communits88. In particular ty. a) Awsting in the of fertilty a￿1 otlw moasw to I￿￿Kove re￿c￿u￿lve and sexual health; and bl Advan(ing education in all aspe(ts cl arwj semol health.

Adelphl Artemls Tn￿t Report ol the Tntstee8 lor the ye8T ended 31 c￿ML￿ 2025 This is fvifilled by rnak5rrfJ grants to appfurts are cor￿1￿ qU8￿fied to organe execute h￿h qua￿ projects w￿h demonstre progress towards one of both ot the Tnjsfs oGtive& Public ben•fft When planning the activitiBslho Truslees have had rwJard to the Chanty Commissioners guidance on the public beneffl of the Trusfs activbtles in particular of educatw)n and the rell8f of poverty as DuUirE above. Re¥lew ol the TTusfs actlvltles and fu￿re developmert¥ The net Inco￿ for the year before gains or losses on imiestments £27 and the Genwal Fund 8131 December 2025 amounted to £745.583 Compared to £780.551 at 31 Decembw 2024. Unrealtsed losses of £34,995 arose as a Tesult of the deuease in ￿ mathel value of the investments that are menayed by the CCLA Fur￿ Managern. Durlng 2025 The TTU3t wntynued fvndtfKJ the thre8TryeaT woiocL ronffwable annuall¥, wilh CHASE Africa to Improve access to famlly pknning ser¥w in marginatised communities in the Tana Rlver ecosystem In Kenya. The gTaTrt period commencod in Juty 2024 and is now in rts second yaw. Conn•¢ted ChaTIty The Ibnked and controllhg charty is Adaw￿. Genelics Forum ith wlK>m the Trust shares Its charty regislrats'on number 2W258. rwslered office WMI Board ol Tnt 8tatèment of Tru8toety' responsibililie$ The law ap￿1¢able to chaTities in England andWg theTnthes to prepore thanclal Stat￿tnts for each year which gNe a true and lair vlvw of the thirW$ financial athltles durlng the yew and Its financlal p05ib.on ot the year end. In pr8penng firranc￿l statem8rts gNbng a true aThJ fair vivw, Ihe Trustees Should fol>ow bgst Frf8Ctice an(J select suknbb& accounlirwJ W)￿¢168 and apt them con8iStenlly. makè judgements and estlmates that are ieasonable and wudgnl.. slate whether applicable aCC￿￿ntIng standards and statements of recormrmjed practre have been follo￿1. suL4ect to any dep8rtUrnS dlsclosed 8nd exF4ained m the financial sLitemw)ts. and prepare Ihe financial stslemgnts QD a going concern basis unkn8 It ￿ inappropTk8le to wesume that tho clwty wkl continue in operalb)n. The Trustees ale responsible lor keaping propor records whth dysck>8e wlth reasonable accuracy al any ￿mE the financial posthon oflhe chanty and whth en3￿ to 8nsur8 thal the fin8nGial 8tatements compiy with ￿ Charits Act 2011. They are also reS￿nsIble for saleguarding the assets of the charrtAble company and hence lor tsking raasonata8 stgP5 tr the WeVent￿ WKI d8tection of frawj and other Irregularities. Andrew P Read H(mor8ry Treasurer Dated.. 18 March 2026

Adelphi Artemls Trust Statsment of financial adivitses for the year ended 31 t>￿7b0[ 2025 2025 2024 Incon Donatsons Investrnents- Investment in¢omo Investments- Bank inthst Total Incom• 3,￿0 20,578 20,437 Charllabl8 ath'vities: Grants Administration c¥J8ts Totsl charita￿8 actiwtse8 15.OLM) 22.134 15.445 Gov8manc8 costs 791 Total oXPondttur• 17 Net Incom•ll•xp•n(l¢urn) baforo galn8llloMes 9,112 Galnslllosses) on Investrnents Nol movom•nt In fund8 (34,968) 25,262 Genèral Fund balances tffought f(xwanl Gen•ral Fund bal•nc•s cwrl•d lon￿rd The Goneral Fund k9 unrestri￿. l amounts relate to cont1￿1r￿ activi￿. The notss on pag88 6 to 9 fonn pwt of those fina￿481 statements.

Adglphl Artemls Trust Balan￿ sheet As at 31 Decemter 2025 2026 2024 Flxed assets Investrnents 8￿.081 731.076 Current assets Investments- Depostt account Cash * bank 64,379 476 62,427 66.721 Cr•dltov•: amounts due within one year Nèt current as8•ts Total a••frts Its• Gurr•nt Ilablllilos Fund¥ General Fund Th• Ggnw81 Fund 18 UFYeStrMA￿. Thè notss pages 8 to 9 f(Ym part ofthese ffinanc￿l statemwts. Th08e financFal statements *re apFovod on 18 M8r¢h 2026. P. R.a. Andrew P Rèad Honorary Treasurer 18 March. 2026

Adglphi Artomis Twst 1 Accounting policie¥ Th8 name of lh8 charity is Adetthi knis Trt￿ It is registered wilh th8 Chartty Commission as a linked chaiity of Adelphi Genetics Forum (cawFty n￿nber 209258). The charitys registered 01￿ce is 19 Northflelds Prosp￿. Lon(kn. SW18 1PE. The prInc￿l accountiry FM)lities adopt&J, JUdge￿n{S WKI key SOW￿ Ofe￿n￿tion uncertalnty in Ihe preparatlon of Ihe financial statemenls are as folk)ws.' The financial stateM￿ts have b88n we¥￿ed In accordarKx ith tho Chartiies SORP 2019 {FRS102) - Ac(x)unltng and ReporlirvJ by Chth: statem￿ of R￿)Mmanded PraLce arthj applicable Unlted Kingdom kqw and accountsng starmdards. Th8 Trust m88ts th8 defi￿110Th crfa ￿kn11c benafft anly under FRS 102. The financlal statements have been weparJ uThJerthe histor￿•1 wStConvent￿. ￿1th the 8xceptlon of Investments whic are IrKluded at markel value. in a¢￿￿ance 7Aryth applicable acounllng standards Golng conc•m Th8 Tn￿te8S consider Ihat there are no Matert￿ uncertainti86 abwt Ihe tharity's abilty to continue as a going concom. Incom• All income is recognlsed th8 tharity h88 ￿tItleM￿tt0 the it 18 wthNethatlhe incx)me wlll be wefved and the mnt of Inojne recelvabk can be measured with sufficient acuJra¢y. Expendlluro Llabllitses are recognlsed as resowcas expended a8 scmin as thore 18 an oblwJatlon commitb'ng the thrity to tho expwxmture. All eXp￿MIllUre Is •xtwnied for on an acryuaLq basis. Grants payablo are payments made to thi￿ parU8s in the fUrlher￿ of thg tharllabl8 Ot¥'8ct4vos of the Trust and are authorised bythè Trustees. UThxxNJFiional grants are rwnisod in full once the reciplont has been Th)tifi￿ ofthe grant award. Vlhwo rnulb. y￿r grarts are sUbj￿t to annual review, they are te¢ogni8ed On￿ the has tsk￿ place arnj that the next years grant is payable. requirements of the charity f86s of ￿ [￿ent EX￿Iner and costs linked to the 8tratsgK rnanagen￿t of the tharity. Th8$8 have t1￿ alk￿a￿l dir• to charitable expenditure. Fund ac¢ountlng All inojme and expthjriure Is taken to Ihe General FurKI. The Trwt has ￿ dosignated ry restiicted purpose fuThJs. R&stricted funds are those sut4ect to $twifK trusty whK* may be by the dorKJr or with their authority. The tharity has Th) rpstri(￿ funds at this

Adelphl Artemls Trust 1 A¢¢ounllng polldès 1￿M￿1n￿d) Investments are i￿lud￿j at market valu8. Rear￿1 gains arNJ losses. th8 dtfferen b8tween sale prcwts m¥ket ¥8￿ al the wevious fin8nc4al yearnd. ￿ purchase cost rf acquired during tr finar￿laS year. are strbxn in the statern￿ d FinarKial ActsvIts￿. In the case of a p8mianent impaimient in the value of investrnents, Fyovision is made in the general in¢4)me and expendilure ￿ltsnt to th8 csrrylng valu8 of inVeStrne￿ to thoir recovor￿e ￿ount. Cash at bank and In hwKI Cash at bank and in hand indud85 cash and stth-tenn hlghly liqukl Invests￿ with a short maturity of three months LY18ss from the date of wuisikn or 0[￿1￿j of the deposit or simitar ￿CoUnt. Credltorn and provl8lons Creditors and pmiston$ arn recognlwj wlwo th8 has a rnsant obligat#)n wising from 8 past event that Vill probabty result in the of fijnds lo a Ihird paty and the amount due lo Settle the ob1W'c￿ can b6 measured or esbmat&J reliably. Creditors are recc3nts¢d al their settlement amount Provbth have be￿ cakJAated at the best estin (rf the sett￿￿t amount. Flnandal Instrumgnts The Trust only has financid a￿ts and fir￿ncIal I￿111118$ of a kind that qualify as buc finan¢ Instruments. Basic finKaal wthments ¥e Inltlalty re(wnis&J al th& transartlon valuo and subsequently measured at their sethment value wrth th8 eX￿ti￿ of bank loans whith are Reallsod galns and losse• AJI gains and10sses are tak•n lo the Ststemont of Financlal Ac￿￿tieS as they arlse. R8ali8ed galns and losses on Fnv8Stments are t￿lculated as the dtffererKe bett￿on sales procegds and thèir opening carying value or Iheir ￿ valu8 rf wilred Subsequent to the first day ofthe financial ye8r. Unreal¢sad gains and tosses are cal￿18t￿d as the dlff6rwKe belwoen the falrvalu8 at th8 year end and their value. Realised a￿1 unreallsed Invests￿ gains aThJ lossas are combined In th8 Statement of Fknancial A(aiVili￿. 2 Ernploye•8 and Tru•ts but may be reimbursed oth of pod(et expel￿S in Ihe pwfmn¢e of Trust duties.

Adelphl Artgmls T￿￿1 3 Admlnistratlon e¢>sts Rg¢harg8d from R•lated p8ty. 2025 2024 Salary Costs Water Rates and SeNke Ch Insurance Repairs and maintena Printing. postage and Stat￿ary Adverusing and marketing Telephone and data costs Websito costs Council meetings Subscrlptions and M￿bershI Bank Charge8 Heat and light Entertaining Sundry Expenses Cleanlng DapredalFon 5,052 32 4.732 27 347 240 249 132 499 550 122 362 241 93 116 130 52 52 26 14 45 381 440 4 Governan¢0 ¢0¥ts 2025 2024 Independent examinatlon Accountancy 88rvic48 1.2CKI 791 5 Flxed aM•ts: Investments Llnllstod Inve•tThnts: 2024 Market value at 1 January 2025 Net Unreal￿ed Investrftent gainslllossas) Market value at 31 tyecember 2025 731,076 714,926 Historical c¥)st at 31 De(￿ber 2025

Adelphl Artemls T￿￿t Not8s to the ffinanC￿ staements forthe yw end&1 31 D￿lber 2025 6 Credltors 2025 2024 The AdelFthi GenelKS F(Mi Grant commitments Accruals 7.134 7.500 719 7 Related paity The Adelphi Genetics FcfftTh (Limited by Gu￿88) is begal entity Ihe ulumate reS[￿SIbIlIty for and control over the Adel￿1 Artemis Tnrt Tho T￿￿t shares th6 Clwity registratiL￿ numbor of the Adelphi Gen8tTh Forum12092581 During the year the Tntsl was rechty costs by A(lephi GenalkA Rnffn 88 8et ￿t in Note 3. The amount due to the Ad&lphi Genetics Fonrn ￿ set out in Note 6. There no other re18ted party transac1k￿.