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2025-09-30-accounts

REGISTERED COMPANY NUMBER: 15157620 IEngland and Wal6$1 REGISTERED CHARITY NUMBER: 1209S24 R8port of tho Tru$t80$ and Flnanclal Ststem8nts for the Year Ended 30 3optsmb8r 2025 BIOS CENTRE Knox Cropper LLP Chartered Accountants and Slalutory Auditors Offlcg SuSte 1 Haslemere House Lower Street Haslemere Surrey GU27 2PE

BIOS CENTRE Contents of the Financial Statoments for tho Year Ended 30 Soptombor 2025 Pagg Report of thg Trust99¥ Report of tho Indopend•nt Examlnor statgm*nt of Flnanclal Actlvltlos Balancg Shoot Notss to tho Flnanclal statements 9 10 21

BIOS CENTRE Roport of th8 Trust985 for the Year Endod 30 8Bptembor 2025 The Trustees, who are also dlrectors of the charlly for the purposes of the Companles Act 2006. present Ihelr report with the financial statements of the charfly for the year ended 30 September 202S. The Trustees have adopted the provlsi¢ns of Accounting and Reporting by Charities.. Slalemenl ol R6commend8d Practicg applicabl to charllies preparlng Ih&ir accounts In accordance wllh the FSnancSal Reporting Standard applicable in the UK and Republic of Ireland IFRS 1021 leffectlve 1 January 20191. OBJECTIVES AND ACTIVITIES Alms and Objectlves Blos Cenlre's obleGt5 ore lo promote research and educallon In bloelhlcs for the publlc benefit including wilhoul Ilmilalion by conducllng orsupportlng the development of research whlch leads to the publlcatlon of peer-revlewed articles and other malerlals of an educallonal nature and by convening galherfngs of researchers and other educalionalisls to review, dl$¢uss and ¢rilique researBh and discourse in the field ol bioethics, includlng conslderalion where appropriate of the interplay between core principle3 of14ippocratic thought and olhei rel&vanl ethlcal prlndples appllcable in ¢ontemporory bloolhlcal contexts. The Bios Centr8 ha5 pursued theso alms through the carrying out of researoh by Centre staff and assoclales, leadlng lo the publication of Peer-￿V￿eWed and more popular articles, and through hosting a full programm• of semlnars and lecture5 on b5oelhlcal Issues. Publlc beneflt The TTuslee8 have referred lo the Charity Commlsslon's publish&d guldance on the public benefit requirement under the Charfjlles Act 2011 when reviewlng Blos Centre s alms and oblecllves. and In planning future activities. In particular, the Trustees conslder how planned aclSvllles will conlrlbuta to the aims and objectives sel and lake care to ensure that all research publlshod by and in the name of Bios Cenlrg Is proporly dlsseminaled. ACHIEVEMENTS AND PERFORMANCE Blos h83 had a productive year In term¥ of publications, seminars and presentations. Grant fundlng from the Trust that made Ihlg possible wa8 in tranches, of £70,000 and £60,000 for years onè and two respectively, but the unconditSonal nature of the grant meant that the total ol bDlh In5talmenls had to b• r•cognl$ed In the ￿r$t perlod of account. As a result, wa started the financlal year with free reservgs brought forward of £59,481. Approxlmalely £27,500 was ralsed from donations and inlarasl in the year, up from £7,059 In the prlor period, enabling the Centre to start the 25126 flnanclal year wlh free reserves equivalent to ju51 short of three months, rurinlng costs and new grant fundlng awards already secured by the dale of Ihls report. Prèsontatlony and mootlng$ holdlattended SIX Centre semlnar8 In¢ludlng a panel dlscussion were held overthis period and a total of 545 people had watched the resulting vSdeo$ by the Ilme of wrlllng. Semlnar presenters came from a range ol academic backgrounds and countries (the UK, Ir&land. Australia and the USI and seminars werg well-recelved by partl¢lpanl8 who, agaln, oame from various counlrles and backgrounds. Staff lectured In bloelhlcs al the Intern811onal Theologl¢al Inslllule, Trumau, and in moral phllosophy at the University of Nolre Dame (London Campus) and presented al Gonferences Such as the UK Clinical Ethics NeNvork Conference and th& Oxford Global Health and Bioethics Inl¢rnatltsnal Conferenc8. Stsff 4180 attended other conferonce8 and webinars and ne￿Tked with madlcal prolessionals and others.

310S CENTRE Report of tho Tru5tegs for the Year Ended 30 Septembor 2025 Rosoarch, publlcatlons and other work Peer-revlowod publl¢alions by Centro ro$¥archers ovar this period included papers in the American Joumal of 8ioethics, the Journ81 of Modicine and Phrfosophy, HEC Forum, v0￿e& in 5ioelhics, Cureus, Nurs& Educatlon I Practice. Tha NewBloGlhlcs, Fonjm dlQu8dernl Costituzlonall. DlrilllCompar8tl. and the Journ81 of M8dlcalElhlcs blog. Staff also produced monthly newsletters for 8ubscrlber&, carried out peer-revlew for bioelhlcs journals and continued to study and WTSle on bioethical topics, thus conlribuling lo bioelhlcs research and educatlon across a range of areas. PLANS FOR FUTURE PERIODS The Centre plans an in-depth exploration of the topic of continuous deep sedation In palllative Caro and related toplc5 In end of life care, to begin earfy in 2026. A COUTsebook on medlcal ethlc5 is also planned. FINANCIAL REVIEW Flnancial Rovlow The re8uII for the year was a deflck of £42,14312024.. £59.4818urplusl. A defick w88 expected aft8r unre8trlcled grgnt incomo of £60,000 glven In relallon to the year ended 30 September 2025 had lo be recognlsed in the prgvlous perlod. Although no furthpr granlswerg rec9ived In the year Income frolll donations In¢reased slgnlficanlly to £26,860 {2024'. £8,504) and bank interest increased lo £67112024.. £5551. There was no income from legacies. Investmont pollcy and obl8cllvo$ Bios Cenlre's investment powers arg sgt out in Ils Mftmorandum & Artlcles of Assodatlon. Day lo day cash flow management Is delegated lo the Treasurer and the Director, who act in accordance with policies agreed by the Trustees. The Investment objective for any funds held in excess of immedlale needs is lo generate the best rale of relum avallable ftom Interest bearing accounts. Funds expected lo be avallable In the short or médlum term may bg Snve$led inlow volalilily net asset value money market funds, R•$&rv&s pollcy Al the year end Blos Cgnlre had only unrestrlcted funds. Blos C•nlrg ha8 no endowed or p?rman8nl funds. Note 15 lo the Accounts gives more Information about reserv8s. Total funds held as al 30 Soptomber2025 wero £17,338 in surplu$12024.' £59,481). Bios Centre's reserves policy Is lo bulld up and rnalnlaln a level of fre8 re3eNes that wlll allow Servlce conllnulty and sufficient time to adlust in a planned and robu$l manngr lo any signrficanl future change in resDurce8. Having revlewed the practical appllcalion of similar Poli￿8$ for other organlsalions wlhln the charllable and voluntary sector, whlch range from Indlcallve free reserve levels of 3 months, operating expenditure lo 3 years, lolal costs requlremgnt, the TrusleBS aim lo hold free re5erve5 equlvalenl to be￿en 6 and 12 months, operollng expendllure. At 30 Sepl8mb&r 2025'fr8e reserves, not lied up in fixed assets or by reslricted purposes were £16,919 In surplus 12024.. £58,922). Theso free reserves amounted to 23% of lolal budgeted revenue costs and deprecialign for th& comlng year, {2024.' 83Vh) compared ￿th a target of befv￿en 50% and 100%. Despite thi$ shortfall il 1$ the oplnlon of the Trustees that a ¢ombSnafjon of r8seNe8 Carried forward and future income from grants and fundraislng wll be adequate lo fulfil the overall obligations of Bios Cgnlro for Ihg next financlal year, and for a period of al least 12 months from the dale of this report.

BIOS CENTRE Rèport of tho Trustags ferthe Year Endgd 30 Septsmb•r2025 STRUCTURE, GOVERNANCE ANO MANAGEklENT Goveming docum8nt BIOS Centre was incorporated 0$ a charflable Cornpany limited by guarantee on 23rd September 2023. Its governlng documentB are the Memorandum and Artl¢les of Association (revised 2024). The Centre is registered th the Charity Commlsslon under the Charilles AGI 2011. Appolntment, in(luctlon and tralnlng of new Trustsos New dlreclors (who are al80 Tru8lee8 of the charilyl may be appointed by ordlnary resolution or by a vole of the dlrectors. From Ilme to Ilme, the Trustee5 review the composillon of the Board in order to gnsure that an appropriate mlx of skS118 and compelencle51s represented, and to Id8nlify any speciflc induction or tralnlng needs that TTuslees might have. Blos Centre make3 use of publicallons avallablè from the Charlly Commlsslon to a8slst Trusteès to undarsland Ihelr dulles. REFERENCE AND ADMINISTRATIVE DETAIL3 Règlstergd Company number 16157620 (England and W8le81 R8gl$terod Charlty numb9r 1209524 Rgglstgrod offlco 3i¢J Floor 86-90 Paul Street London EC2A 4NE Tru8tg9$ Dr F T Contatto- ChaSr Prof P R Casey Prof D S Oderberg lappolnled 22.07.25) Prof G Pezzlnl {appolnted 22.07.251 J P Alherton FGA- Treasurer Indgpgndonl Examlngrs Knox Cropper LLP Chartered Accountants and Slatulory Audhors Offl¢e Sulle 1 Haslemere Hou8e Lower Street Haslemofe Surrey GU27 2PE

BIOS CENTRE Rgport of thè Trustses for the Yoar End&d 30 Soptembor 2025 STATEMENT OF TRUSTEE8' RESPONSIBILITIES The Trustees (who are also the directors of Bios Cenlrg for the purposes of company lawl are re3pon8ible for preparfng the Report of the Trustees and the financial slalem&nts in accordance wllh appllcablo law and Unltgd lQngdom Accounllng Standard3 Iunlled Klngdom Generally Accepted Accounting Practic81. Company law requires the Trust¢e8 lo prepare flnanclal gts18menls for each fln8nclal year whlch give a true and falr vlew of the 81ale of affalrs of the charitabl• company and of the Incoming resources and appll¢allon of resources, Including the income and expenditure, of the Charitable company for that perfod. In preparlng those rinanclal slalemenls, th9 Trustees are requlred lo select suitable accounting policle$ and then apply them conslstently., observe the methods and prlnclples In the Charity SORP., make ludgeTnanls and estimates that are reasonable and prudent., prepare the flnancial slalemenls on the golng concefn bA8I8 unless il is inappropdate to presume that Ihe charllable Company wlll conllnue in busine$$. The Trustees are responsible for k&eplng proper aCcoL*nI￿n9 records which dlsclose with rgasonable accuracy al any lime the financial position of thg charflable company and lo enable them lo ensure that the financlal 3talemenls ¢omply wlh th• Companies Act 2006. They are also re8pon5ible for Safeguardlng the assets of the charitable company and hence tor laklng reasonable slaps for the pievenllon and delectlon of fraud and other Irregulafllles. Th1$ report has been prepared In accordance vlth the speclal provlsions of Part 15 of the Companies Act 2008 relating to small companies. Approved by order of the board of Trustees on 17￿ March 2026 and slgned on ts bghall by: F T Contallo- Truslge

Indepondgnt Examlnor's Roport tu the Truste9¥ of Blos Cgntro FOT thg Year Endod 30th S•ptgmbgr 2025 Indep•ndent •xamlnerf8 roport to tho trustsos of Blos Cgntro Company'l I reportto the charmy Iruslee3 on my ex8mln8tlon of the accounts ofthe Company for the year ended 30 Septembor 2025. R•sponslbllltl88 and bas1$ of report A8 the ¢harty's Iruslees of the company land also Its dlre¢lors for the purposes of company law} you are responslble for the preparallon of the accounts in accordance wth the requlremenls of the Companies Act 2006 {'the 2006 Acl'l. Havlng 8atl8fied myself that the accounts of the Company are not requlred lo be audtted under Part 16 of the 2006 Aol and ar9 ellglble for Independent examlnatSon, I report In resp¢¢l gf my oxamlnallon of your Charity's accounts as carried out under Section 145 of the Charilles Act 2011 I'lhe 2011 Act'l- In carrying out my examlnallon I have followed the Dlreclions given by the Charfty Commi88ion under Section 145151 Ibl of the 2011 Act. Ind8p8ndant •xamlner'$ statsmant I have completed my 6xgmlnallon. I confirm that no matters have come lo my gttanllon In connectlon wlh the examination giving me cause lo believe.. accounting records were not kept in respect of th& Company as required by S¢¢lion 388 of the 2006 Act., or the a¢counls do not accord wSlh those records., or the accounts do not comply with the accounting requirements of Section 396 of the 2006 Act other than any ¥equiremenl that the ac¢ounls give a true and falr vlew which 18 not a matter considered as part of an independent examination., or the accounts have not been prepared in a￿OrdanCe wllh the methods and prlnclples of the Slalemenl of Recommended Practice for a¢¢ounling and repgrting by charities lapplicable lo charities preparing Ihelr accounts In accordance with the Financial Reporting Standard applicable in the UK and RepublSc ol Ireland (FRS 10211. I have no concerns and have comg across no other matters In connecllon wllh thè examlnallon lo whlch attenllon should be drawn In this report in order lo enable a prop8r underslandSng of the acco(tnls lo be reached. Matthew Elkins FCA Knox Cropper LLP Chartered Accountants Offic& Suite 1, Haslem8r8 Hous Lower Street Haslemere Surrey GU27 2PE .2026 Page 5

BIOS CENTRE Statèment of Flnancial Actlvities for tho Y&ar Ended 30 Septsmb•r 2026 2025 Total fund5 2024 Total funds UnreslriGted funds Restricted furK15 Notes INCOME AND ENDOWMENTS FROhl Donallons and legacles 26,860 26.860 136,504 Charitable actlvlties Investment Income 671 671 555 Total 137059 EXPENDITURE ON Raising funds 4,577 4,577 4,928 Charllable activ6tie5 72.650 Total NET INCOMEIIEXPENDITUREI Tran8f•rn between funds 142,1431 142,1431 B9.481 15 Net movemgnt In funds 142,1431 142,1431 59.481 RECONCILIATION OF FUNDS Totsl funds brought foNard 59,481 59,481 TOTAL FUNDS CARRIED FORWARD 17.338 17.338 Thg note$ form part of Ihosg flnancial slalamen15 Page 6

BIOS CENTRE Balan¢¥ Shoot 30 Saplgmber 2025 2025 2024 Nol88 FIXED ASSETS Tangible as$el8 12 419 559 419 559 CURRENT ASSETS Debtors Cash at bank and In hand 13 799 60,965 657 23,974 61.622 CREDITORS Amounts falllng due ￿thIn one year 14 17.0551 {2,70DI NET CURRENT ASSETS TOTAL ASSETS LESS CURRENT LIA81LITIES 17,338 59,481 NET A88ET8 FUNDS Unreslricled funds Reslricled funds 16 17,338 69,481 TOTAL FUNDS The note5 form part of these flnanclal statements Paga 7 ¢ontlnued...

BIOS CENTRE Balanco Sheot . contlnuod 30 soptgmber 2025 For the flnanclal year In qugsllon, the company was entllled to e¥empllon under sedon 477 ofthg Companies Aot 2006 relallng lo small companles. No members have required the company lo oblaln an aud￿ of ts accoun18 for the year In question In accordance th secllon 476 ofthe Companles Act 2006. The directors acknowledge their responsibility for complying with the requiremen15 of the Act wlh respect to aceountlng records and for the preparatson of accounts. These flnanclal 8lalemenls have been prepared In accordance the provlslon5 appll¢able lo Gharilabl companles subject lo the small companlos r&gime. The financlal statements were approved by the Board of Trustees and aulhortsed for153ue on 17th March 2026 and were slgned on Ils behalf by.. F T Contatlo- Trustee J P Alherton- Trustee The notes foim part of these financial 51alemen15 Poge 8

BIOS CENTRE Not98 to thg Flnancial Stat0ment5 for thg Y8ar Ended 30 Soptember 2025 ACCOUNTING POLICIES Ba$l$ of pr¢parlng the financlal statsmBnts The flnanclal $latemÈnls have been prepared In accordance wllh Accountlng and Reportlng by ChaTille5'. Slalemgnl of Recommended Pra¢lice applicablo lo charftles preparlng Ihelr accounts In 8ccordance wlh the Financial Reporting Standard applicablo In the UK And Republic of Ireland IFRS 102) Second Edlllon Issued In October 2019 - (Charities SORP IFRS 1021), the Financial Repcrtlng Stsndard applioablg In the UK and Republlc of Ireland IFRS 102) and the Companies Act 2006. Bios Centr8 moets the deflnltson of a publlc benefit enllty under FRS 102. A88et8 and118bllllles are Inllially recogni5ed al hlstorl¢al cost or transaction valu• unless otherw58 slated In the relovanl accounllng pollcy nolelsl. The charitable company has taken advantage cf Paragraph 3131 Sch 4 of the Companles Act 2006 and adapted CompAnles Act foimals of accounts to reflect the charitable nature of the COfTipany's aclSvS1I89. B508 Centre Is a company Ilmlled by guarantee, Incorporated In England and Wales, and has no sharo capital. Every member of the company gUorantee8 to contribute a maxlmum of £10 on winding up. 11$ registar&d Office is silual&d al 3￿ Floor, 86-90 Paul Slr$el, London EC2A 4NE. The finan¢lal statements are prepared In In slerlSng. which Is the lunctlonal currency of th& company. Monetary amounts in thos9 financial slalemenls are rounded lo the nearest £. crftlcal ac¢ountlng judgements and k•y 80urces of •stlmatlon uncortalnty Deproclalion - The depr8¢lalk)n of fixed assets 1$ based on management's e51imale of Ih&lr useful Ilve8 which is kept under review. Incom Incomo from voluntary 8ourco$ and lundralslng Income Includes voluntary sources of Income such as charllable donation, grants, glfls (￿th related lax recovery where appropriatel, legacles. appeals and collections. The cost of runnlng these programmes during the perlod was £4,928 and Ihls is included within the headlng 'raising funds, shown under Expenditure, and in Ngte 4. The follo￿n9 spe¢lfic pollcle8 are applled lo partkulaT catogorles of voluntary incomo and fundraising. Unrestrlcled voluntary donations and glfts are aecounled forwhen fhey are received, as Ihls Is the polnl al which the necessary detail becomes avallable lo allow them lo be entered Into the accounlSng record8,' 11 Ss also the point al which they become sufflclenlly certain lo b& recognised. Legacle8 are slmilarly accounted lor when re¢elved unless there Is sufficient reliable Inlorrnalion for them lo be accounted for earller. Reslricled Income is acetsunled for within Reslricled Funds when 51 is re¢eivable Ilf Blos Centre ha8 been nolifiedl. Grants, where enlillemenl is not condltional on the delivery of a speC￿lC performance by the charity, are recognised when the charity becomes uncondlllonally enlilled lo the grant. Expenditure related to Roslricled Funds 1$ matched lo Income accordanoe wllh the terms ol the award or grant. Page 9 contlnugd...

BIOS CENTRE Noto8 to tho Flnanclal Statempnts - contlnugd for tho Year End&d 30 September 2025 ACCOUNTING POLICIES - Continued Incomo Donalod $eTvlces, facilities, and other glfts and donallons in klnd are a¢¢ounled for the Slalemenl of Financial Activities when they are received and al an appioprlale value lo the charity where this Can be quanlllied and where malerlal. CoTrespondSng addlllon3 to Flxed Assets, Stock or operallng costs are made according lo the nature of the Item. The value ol servlces provlded by volunteers has not been Included these accounts. Income from charltablè actlvltl•s Aotivilles whlch further the charltoble obleclives of Bios Centre Include.. Re$earch and publlcallons in the field of BloelhScs', and Lectures. seminars and events In some ￿$95, these activill8s havo polgntlal lo glve r15e to 50urce8 of oper?Ilng Income from 8ponsor8hip, royallles, contract fees. $ervtce level agreemanls and lickel sales. No such income was recelved In the perlod. Any such arrangements would be lightly govèrned by the Centra's 'Poll¢y on Research Partners and Sponsors, or 'PolScy on Seleollon of Speakers,. Portngr8 and Sponsors., and AdvertislnglDisplay of Publlcgllon5 al Bios Contre Events, a5 approprlale lo ensure that the Centre malnlains hlgh standards of Inlegrlly and credbbllity in ils sele¢llon of and Inl8ra¢lions with partners, Sponsors, speakers and publl¢allons. In the case of dlscrelionary grants awarded lo Blog Centre by charStable OT philanlhioplc trust8 and foundations, gach grant maker wll have its own appll¢ation and monSloring proceduras, and awards are usually sublecl lo annual renegoliallon or finlle periods. The costs of sourcing, negotiating, managing and reportlng upon such lunding arrangemgnls are accounted for as a cost of provlding the relal•d $ervices. Any Income from contracts and other forms of agreément lincludlng some described as 'granls'l, where rglaled lo performance and spe¢iflc dellverables, ￿11 be accounted for as the ¢harfty eams the rlght lo consideration by Ils perfomiance. Any fees wlll be accounted for when recelvable. Expgndltur• Expendlture Is recognlsed on an accruals bas15 as Ilabilllies are incurred. Bios C8nlro Is not reglslered for VAT. Expendilur81s allocated to the followlng cg51 cenlres uslng methods generally accepted in the so¢lor Ilhe ACEVO model for ￿81 analysis, adapted lo ensure complSanc& wllh the Charities SORPI.. Costs of Ral8ing Funds,. Includln9 both dlrecl and Indirect allocations of payroll cost and admlnlslratlve overhead, and direct costs associated wllh allracllng voluntary in¢orne and carrylng out fundralslng a¢￿'vItieS. Support Costs Includlng Governance Costs,. Include diroct and indirect costs of complylng wllh all necessary conslilullonal and slalultsry requirements ol the charllable oompany and Ils slraleglc managomenl and rlsk assessmentlmanagemenl procedures. Charflable Aclivilitts costs., comprlslng those Costs incurred by the charity In the dellvery of 118 acllvllles and service8. 11 includes both directly allrlbuled ¢o$ls, and allocallons of indirect costs and overhead8 that are necessary lo support them and wilhoul which il would not be possible lo continue them. P8ge10 continued..,

BIOS CENTRE Note$ to th? Flnancial Statsments - contlnuod for thg Y•ar Endgd 30 S•ptsmb•r 2025 ACCOUNTING POLICIES • contlnuad Exptndltu Atl ¢¢sls are allocated be￿89n Ihesg cost centres (expendllure calegorles) on a falr and conslslenl basls inl8nded lo reflect the ustr of the resource. Many types of c031 include items that can be directly allribuled, as well as a pool of costs Ihgt are doall with by apportlonmenl uslng an appropriate basis Such a5 Staff lime allocatlon, or another reasonable ludgemenl of consumption. The Information sel out In Notes 4 10 7 summarlses the outcome of del8Sled cosl allocatlon5 based on the ACEVO model a8 explalned above. Tanglbla flxgd assèts Assets are capilalised wh8Te their indlvldual value exceeds £500. Fixed Assets are slated al ¢osl. Depreclallon is provided on all tangible fixeil agsols al rale8 calculated lo write off the cost of valuallon, less esllmaled resldual value, of each asset avgnly ove1118 expe¢led useful Ilfe on a Stra￿hl-lIne basis. The rat8s usad in each category are a8 follows.. Office & IT equlpment 5 years Whtrre depreciation is charged against assets represenllng reslrlcled and designated funds, Ihls depreclalion is charged ggalnsl that lund as il arises. The carrylng valu•$ of tangible fixed assets are ravlewad for Impalmienl If events OT changes in clrcum8lan¢ès Sndlcale that the carrylng value may not be rgcoverable. Stocks Stocks are valued at the lower of ¢081 and nel reallsable value, after maklng allowance for Obso￿te and sjow-movlng ￿ern$. Taxatlon The Gharlly Is gxempl from corporallon lax Sts charftsble acllvilles. Fund accounting Unreslrlcled fund8 arè defined as grants and other Income recewed or generated for Ihe oblectivgs of the Qharty wilhtsul further specified purpose and whlch are available as general funds, bul which may be required for committed projects or deslgnated by the Trustees for ¥pedflc purposes. Reslrlcled funds can only be used for parts'cular restricted purposes wllhln the object8 of the charity. Rgslrlcllon8 a￿se when spedfied by the donor or when funds are ralsed for particular r&stricled purposes. Further explanatlon of the natUT8 and Purpo￿ of each fund Is Included In the notes lo the flnanclal slatemenls. RKerv08 Bios Centre recognises that accounllng reserves are not always represented by avallable Ilquld assel8. Note 15 sets out how reserves I'fund8'1 are representèd at the balance sheet dale. Additional detall Is also glven In Ihg Trustees, Report. The Trustees have sel an inltlal largel to hold batwagn 50% and 100% of total budgetgd ￿$ts for the ensvlng year In acce35lble free re8erve8. Page11 continued...

BIOS CENTRE Notes to tho Flnanclal Statèm•nt8- ¢ontlnued fortho Ygar Endgd 30 Saptsmber 2025 ACCOUNTING POLICIES - contlnuèd Golng Concgm No mal6rfal uncertalntles that may cast slgnlflcant doubl about Ihg ablllty of the company lo contlnue as golng concern have been Ident6fied by the Trustees. The Trustees plan Ic> keep the ¢harlly as a golng concern lo pursug the Ams and Oblectlves sel out In the Trustees, Report. Debtots Trade and other debtors are recognlsed at the set118menl amount due after any trade dlscount offered. Prepaymen15 are valued al the amount prepald net of any trade discounts due. Cast at bank Cash al bank and cash In hand Include8 cash and short term highly Ilquld Snveslrnents with a Short malurfty of three month8 or less from the data of a¢qulsilion or Dpenlng of the depo$ll or slmilar account. Crndltors Cr¥dltors and provlslons are recognlsed where th8 charfty has a present obllga￿on resumng from a past event that will probably result in the Iransfar of funds to a Ihlid party and the amount due lo settle the obllgalion can be measured or esllmaled rellably. Credllors and provislons are normally re￿gnIsed at Ihelr settlement amount after allowing lor any trade dlscounts dLIe. Page 12 onllnued.

8108 CENTRE Note$ to the Financlal Statomgnts - continu8d for the Yoar Ended 30 Septfjmbor 2026 DONATIONS AND LEGACIE3 2025 Total funds 2024 Total fundg Unrestricted fund8 Ra$lrlcted funds Donations Legaoies Grants 26,860 2fj,860 6,504 130000 26,860 Grants rec8lv8d, Induded In th8 above, are as follows.. 20215 2024 Other granl$- SPUC Eduoallon and Research Trust 130 000 Included In the grant from SPUC Educallon and Resèarch Trust was £60.000 recelvablo In the 2024125 finan¢lal year. INVESTMENT INCOME 2025 Totsl funds 2024 Total funds Unrestricted funds Reslrfcled funds Deposit account interest 871 671 555 671 671 555 Page13 conllnLied...

BIOS CENTRE Not95 to the Flnanclal Statomonts - contlnued for tho Year Endad 30 soptember 2025 RAISING FUNDS Ralslng donatlons and legaclos 2025 Total funds 2024 Total funds Unrestric18d funds Restricted funds staff costs Insurance Premisas & utlllllos Communications & IT Prlnllng & Promollon Other costs Fundralglng Support ¢osts1gee note 71 3,975 27 22 35 3.975 27 22 35 4,196 20 23 23 332 183 332 183 665 CHARITABLE ACTIVITIE8 COSTS Dlre¢l Costs (See note 61 Support cost$ (see note 71 Totals Research and semlnars DIRECT COSTS OF CHARITABLE ACTIVITIES 2025 2024 staff costs Insurance Premi588 Communlcallons & IT Relerence malgrial & con8umab1è5 other co315 Prlnling & promotion 60,9S1 413 340 639 61,834 292 334 32 32 12 Page 14 continued...

BIOS CENTRE Notès to the Financial Statements- contlnuod for th8 Y8ar End•d 30 S•pt•mb¢r 2025 SUPPORT COSTS 2025 2024 Ralslng funds Rasearch & serninars 183 665 Support costs, Included In the above. are as follows.. 2025 Total fund$ 2024 Total fund8 Research & 8emlnar8 Ralslng funds Legal and profe$$ional fees Accountancy & compllance Communlcatlons & IT Bank ¢harges Stsff costs Depreclatlon 7,140 900 956 873 431 131 1,244 131 57 28 930 459 139 1,32S 140 81 1.325 140 2.810 183 NET INCOMEIIEXPENDITUREI Net In¢omel(expendllurel is slated after ¢hargingllcTedlllngl'. 2025 2024 Deprecl8tion- owned assets Independent Exèmlnerfs remuneratlon 140 930 140 900 TRUSTEES. REMUNERATION AND BENEFITS There were no TTuslees' fftmuneralion or other benefits for the year ended 30 September 2025 or Ihg perlod 23 September 2023 to 30 Seplembfjr 2024. TrusteDs' 8xpons•$ There were no Trustees, expenses paSd forlhe year ended 30 Seplembgr 2025 orthe perlod 23 September 2023 to September 2024. Page 15 conllnu8d...

BIOS CENTRE Noto$ to the Flnancial Stat8m•nt8- contlnu•d for th9 Year Ended 30 Soptombor 2025 10. STAFF COSTS 2025 2024 Stsff costs.. Wages and salarle8 Soclal 5e¢urlty c08ts Pension contrlbulions 62,6Q1 63,542 67,355 The averagg monthly number of emtAoy8e8 durlng fhe year wa8 a8 follows.. 2025 2024 Charltable actlvllles There were no employee5 whose employee beneflts exceeded £60,00012024'. nill. Key management personnel compri$* the trustees and the Cenlre's dlr9clor. Total employee beneflls payable to key management personnel for the period amounted lo £26,50012024'. £26,500). Page 16 conllnued.,.

BIOS CENTRE Notes to the Financial Statomgnts - contlnued for th• Yo•r Ended 30 September 2025 11. COMPARATIVES FOR THE STATEMENT OF FINANCIAL ACTIVITIES unreStr￿ted nds Rèslrlcted funds Total Yunds INCOME AND ENDOWMENTS FROM Donallons and legacie$ 136,504 136,504 Charitable acllvllv&$ Investment income 555 555 Total 137059 137 059 EXPENDITURE ON Raising funds 4,928 4,928 Charitoble ac1￿11[e3 Total Nel gain$ on inve$lmen18 NET INCOMEIIEXPENDITUREI Transf•rs botween funds 59,461 59,481 Not movèm8nt In funds 59,481 59.481 RECONCILIATION OF FUNDS Total funds bmughl forward TOTAL FUNDS CARRIED FORWARD Page17 contsnued...

810S CENTRE Not•s to th• Flnan¢lal Statemonts- contlnugd for tho Year Ended 30 S•ptembeT 2025 12. TANGIBLE FIXED ASSETS Office & IT equipment Totals COST Al 1 October 2024 Additions Dlsposals 699 699 At 30 September 2025 699 699 DEPRECIATION Al 1 October 2024 Charge for year Ellminaled on dlsposal 140 140 140 140 At 30 September 2025 280 280 NET BOOK VALUE AI 30 September 2025 419 419 Al 23 Saplember 2024 559 559 Page 18 continued...

B103 CENTRE Notes to tho Flnanclal Statements - contlnugd fortho Yoar Endgd 30 Septsmbèr 2025 13. DEBTORS: AMOUNTS FALLING DUE WITHIN ONE YEAR 2025 2024 Trade debtors Other debtors Prepayments and accrued Income 799 799 1& CREDITORS: AMOUNTS FALLING DUE WITHIN ONE YEAR 2026 2024 Trade creditors Social security and olher taxes Other credllors Accruals Deferied Sncomg 54 691 5,396 934 737 687 396 900 15. ANALYSI8 OF NET A83ETS BETWEEN FUNDS 2025 Total funds 2024 Totsl funds Unraslricled funds Re3tricled funds Flxed assets Current assets Current liabi1111¢8 419 23,974 419 23,974 559 61,622 Page19 conllnued...

8108 CENTRE Notgs to tho Flnanclal Statements - ¢ontlnuod for Iho Yaar End&d 30 SoPt¢mbor 2025 16. MOVEMENT IN FUNDS Nel movement In funds Ti8n8fer8 be￿en funds At01.10.24 At 30.9.25 Unrostrlctgd funds General fund 59,481 {42,1431 17,338 Re3trictgd funds Rèslrfcled funds TOTAL FUNDS 59.481 42 1431 Net movement In funds, Included In the above are as follows.. Incoming resources Resources expended Galn5 and losses Movement In fvnd8 Unr9Strlctod funds General fund 27,531 (69,6741 142,1431 Rastrlct•d fvnds Reslricled funds TOTAL FUNDS Page 20 conllnued...

BIOS CENTRE Nvtes to tho Flnanclal Statemènts - contlnuod for the Year Endod 30 SgPtgmb$r 2025 16. MOVEMENT IN FUNDS - contlnuod Comparatlvgs for Movemont In Funds Nel mDvement In fund3 Transfers betwe?n fund$ At 23.9.23 At 30.9.24 UnTeStrlct8d funds General fund 09,481 59,481 Restrictod fund$ ReslrS¢led funds TOTAL FUNDS Nel movement In funds, Included In the above are a8 follows.. Incornlng resource$ Resources expendgd Galns and losses Movement n funds Unr•strlct•d fund$ G8n8ral fund 137,059 177,5781 59,481 Restrlctod fund5 Reslricled funds TOTAL FUNDS 137 059 17. RELATED PARTY TRANSACTIONS During the year John Atherton, a Irusloe, advanced an intero81 free loan 01 £5.000 lo the ¢haTily lo be repald In the followng financlal year. Page 21