Observe the methods artd principles in the Charities SORP. 3. Make reasonable and pruderlt judgments and estima. 4. Prepwe the financia) sthtements on a going-concern basis unless itiappropriat¢. 5. Mainrain adequatr accountiDg records and impl¢meni effective internal controls. Approved by tbe Board of Trusttts on110 2taffand sigoed ots its behalf Bernard MorleL Chair Gary Shields. Treasurer
events. This body has also mandated compulsory "Black Box" warnings to be included in ail packaging containing Finasteride. Challetyges: Securing repeat funding from a donor base that is largely financially compromised, and baiancing r4)id projeet initiation with prudent reserves management. On-going dialogue with the MHRA to obtain recognition and rep)rting of lived patient experiences when they follow nationa15v #pproved guidelines and instn]ctions. 5. Financial Review Total in¢omiDg resou £30.902 Total resources expended: £27.261 Net movement ID funds: £3.641 Cash funds ¢arried fonv4rd: £3,641 Reserve5 Policy: Trusices aim io hold unrestriried reserves equivalerkt lo approximately 12 months of running costs (c. £1,000). As at l August 20?4: free reserves st(bod at £1,618. R¢stricted start-up funds havc provided additional flexibility. Principal Funding Sources: Individual donations, raised on the widerstanding that donors will noi be placed in financial hardship by their contributions. 6. Plans for Future Periods l. Diversify FundiDg Base: Target corporate donors, private philanthropic foundations and government grani programmes. 2. Patient Database Project: Se¢ure corc funding to develop a comprehensive patient registry to identify sympiom-profile pattems and potential biomarkers. 3. Digital Outreach: Launch a YouTube channel to setve as an accessible inforniation hub for PFS and PSSD communities. 4. Political Engagement: Lobby key MPS and fom) a cross-party. group to influen¢e men s and young people's health policy, enhancing submigsions to regulators and scientific nomenclature bodies. 7. Trustee Responsibilities Statement The Trustees (who also act as Directors for company law purposes) are responsible for preparing this report and the financial statements in accordance with applicable law and United Kingdom A¢¢ounting Standards (FRS 102). They must: l. S¢lect and apply suitable acwunting policies consistently.
- Objectives, Public Benefit and Activities Charitsble Objects: To promote scientific research inlo the prevenliory cure, manogement and all¢viation of iatrogenic diSeaS1ncludIllg, but not limited to, Post-FinasterÉde Syndrome-by providing funding on the condition that useful research results are disseminated for public benefit. Publi¢ Benefit: The truste¢s ¢onfirni that they have had du¢ regard to the Charity Commission's publi¢ benefit guidance in plas)ning and delivering activtties during the reporting period. By funding indeperhden( scientific res¢8rch. raisingT awareness among healthcare professionals and the wider public, and facilitaling improved adver3e- effect retK>rting. the ¢tY has: Advanced und¢tanding of PFSIPSSD pathophysiology, benefiting curr¢nt and future patienLq through peer-reviewed publications and data-sharing networks. Improved patient outcomes by disseminaiing p11¢2[ infonnalion and resources. leading to earlier recognition and management of adverse effects by clinicians. Enhan¢ed regulatory safeguards by collaboraiing with the MHRA to refine adverse- event reporting workflows, reducing tht risk of under-reporting and safeguarding public health. Aetivities during S June 2023- 1 August 2024: Fundraising: Raised £30.902 in donations predominantly from patients and family members. Grant-making: Committed approximately £24,0(K) to fund Professor Melcangi's 'Milano Project" at the University of Milan, a seven-investigalion initiative translating preclinical PFS findings toward human trials. S¢ientific ETrgagement: Searched for and screened additional resear¢het3 to investigate underlying mechanisms of PFS and Post-SSRI S¢xual Dysfun¢tion (PSSDI. Awareness attd Advocacy: Orcheslrat¢d'fv, radio and press interviews to highlight the scale 2nd severity of fin&8teride side-effects. Engaged the MHRA to improve adverse-eff¢¢t pOrting accuracy and timeliness.
- Achievements and Performance Research Funding: Enablf>J acceleration of two ongoing and five new clinical- translational studies within the Milano Proje¢L targeting completion of illVf3tigations by end-2026. St*keholder Collaboration: Established dat&sharing frameworks with UniveT5ity of Milan and initiated discussions With UK research partheTS for parallel siudies. Public Aw8reiies5: Secured multiple media rtUreS. reaching an estim&ted audience of over 250,000 and improving professional awar¢ness among healthcare providers. Regulatory Engagement: Md with MHRA representatives twice, rcsulting in revised guidan¢e for health¢are profe55ionals on re¢ording and TfWrtiE]g PFSIPSSD
Sidefxhub.UK Trustees, ADnual Report for the perind ending l Allgust 2024 {Period: S June 2023 to l Augllst 2024) l. Reference and Administrative Details Ch•rity name: Sidefxhub.UK Registered cbarity Dwtnber: 1203385 Registered otrice: 66 Leam Terrace, Leamington Sw CV31 I BQ Tru$teo8 who servwl during the period: l. Cjary Shield5 {Treasurer) 2. Katharine Hayden (Scientific oificer) 3. Bernard Morlet (Chair) 4. Robert Dixon (All Inutee appoinlmenls arepatient- or beneficiary-led, or involvefamily members ofpalienls. recruil¥d by invilalion.) Board of Directors: l. Gary Shields 2. Morten Skov 3. Robert Dixon 4. Bernard Morlet (Pulient- orfumily-member-led, elIng ui leasl weekly with daily communication needed.) Key advisers: IDdependeDt Examijber: Max RetallacL TC Group Business Advisors & Accountants Bankers: The clperatIve Bank Community Dirwt Plus Account (online) WISE Foreign Currency Account {online) 2. Structure, Governance and Management Sidefxhub.UK is constituted as a Charhtable Incorporated Organisation (CIO) under English law. Overall wntrol is vested in the Board of Trustee5. who set strdtegic direction and oversee governance. Day-to-day decision-making is delegated to a patient-led Iloard of Directors. which meets weekl). (with continual daily liaison) io manage operations and put the trustees, policies into practic¢. A forn1 risk-register is maintsined and reviewed quarterly, covering financial stability, safeguardin& and regUlary compliance.
Notes lo the accounts for the period ended I" August 2024 l. Aecounting policies {a) Basis of pretiO The financial Stslem¢nts have been prepared in accordance with the Charities Act 2011, J¢counting and reporting by charities= Statement of Recommended Prdctice applicable to charities preparing their accounts in accordance with the Financial Reporting Siandard applicable in the UK and Republic of Ireland (FRS 102) (effective I st October 2019) (Charity SORP FRS 102) and the Financial Rertirtg Standard applirable in the UK and Republic of Ir¢land (FRS 102}. Sidefxhub meets the definition of a public benefit entity under FRS 102. Assets and liabilities are initially recognised at hisioriial cost or trdnsa¢lion value unle55 Qtherwise ststed in the relevant accounting policy note. The financial statements prepared on a going ¢oncem basis under the historical cosi ¢onvention. modified io include certain items at tair value. The financial statements are prcsented in sterling whi¢h is the functional ¢UTrency of the charity and rounded to the nearest £1. (b) PreprtlOD of accounts on a going coucerll basis The Trustees consider that the principal uncertainty regarding going concern relates to the ability lo rai%e funds. The Trusiees monitor fund raising results and expenditure (a¢tual and for¢c&8t) to mitigate that risk. (c) Volunteers The value ot s¢rvices provided by volunieer5 has not been included. (d) Income Income is included when rec¢iv&ble. Where income has conditions attached to it. that income is recognised when there is c¢rtJinty of receipL entiilement and the amount can be measur with sufficient reliability. Income (including granis receivable) is deferred where ¢onditions exist on entitlement such &s a specified future time period. {e) Expenditure Expenditure is recognised in the period in which it is incurred and includes atiributsble VAT whi¢h cannot be r¢covered. Expenditure is recognised when a legal or constructive obligation arises. Costs of raising funds are those Costs IncUed in attracting voluntary incotne. Govemance costs are those costs incurred in th¢ &Fovernan¢¢ of the charity and its &ssets and primarily associated with constitutional and statutory requirements.
BalaDee Shee¢ As at l August 2024 Notrs 2024 Current Assets Cash at bank and in hand Totsl CurreD¢ Assets 3,641 Otber debtors Pr¢paymeDts Current Liabilities Totsl Assets le&s crrent Liabilities 3,641 Net A55ets 3.641 Reseryes UnrL%tricted reserves Restricted reserves 1,637 2,000 Totsl Rese¢$ 3.1kn41 Apprnved by the Trustees OD Date sigDed on their behalf by: Trustee
Ststemettt of Financi41 Aetivities Income & ExpeDditure For the riod ended l Au ust 2024 Ilnre5trired furlds Restrirted frtd$ TotAI funds to th¢ nearest lo the negrest to tht nearest Al Receipts UiQ dortdiions in GBIJ UK donations itt kind in GBP 256 256 Ntsn-UK donalions in GBP Bank Inierest Non-llk Ih)naiions in b.uros 27.82 (GBP equivdni Smb irt&1(GrS iMcomeforAIU 24 24 2S642 5360 30,2 Tothl recelpts 2&642 $260 30.902 A3 PaymtntS i.'r & Computing 3.194 3,194 Donations & (irants 24.1 Batjk f¢¢s 43 Pjiymcnt proce&5ing fees Z4 Sub ith 37 27361 24,024 3337 27 61 Ne1olrec1PlWtsj 1,618 2.02J A5 Tr*u$f¢rs between fyttds A6 CAsh fuudslost yur eHd 1.618 2,023 3th41
IDdependent Examiner'sl Auditor's Re OD 8c¢ounts for the perl( 1° AUgl 2024 ¢Dded ort to the Trustees of Sidefxhub.UK Ch•rity Ro 1203385 Set out on pages Ito5 I report to the tru5teas on my exwninxtion of the accounts of the &ix)ve clthrity ("th¢ Trust.) for the F¢riod ended 01108n024. RespoD$lbtutl¢8 #ttd bas15 of As the charity tn]str£5 of the Tn. you are responsible forth¢ pryaration of the report accounts in ¥cordance with the requirements of the Cbarities A¢t 2011 fthe Act"). I report in Tesp¢d of my examinatioft of the Trust's accounts carried out under section 145 of the 2011 Act and in carrying out my examinatio I have followed the appli¢abl¢ Directions given by the Charity Commission under section 145(5Xb) of the Act. I have completed my ¢xamina¢ion. I confirni that no material matters have Come to my attention in connection with the ¢xamin&tion which gives me cause to believe in, any material r¢spe¢t: accounting records were not kept in accordance with wtion 130 of the Act or the accounts do not accord with the accotmting records Independent examiDerfs statsment I have no concems and have com¢ across no other matters in conne10n with the examination to which artentioD should be drawn in order to ¢nabl¢ a proper understandkng of ihe a¢eounts to be reached. Slgn¢d: DAte: 20 May 2025 Namv. Max Retsllack Relev4Dt professiottal qu811fall0n(5) or body (If any): FCCA Addresj: Nelson House. 2 Hamilton Terrace, Learnington Sp4 Warwi¢kshire CV32 4LY