Observe the methods artd principles in the Charities SORP.
3. Make reasonable and pruderlt judgments and estima￿.
4. Prepwe the financia) sthtements on a going-concern basis unless itiappropriat¢.
5. Mainrain adequatr accountiDg records and impl¢meni effective internal controls.
Approved by tbe Board of Trusttts on110
2taffand sigoed ots its behalf
Bernard MorleL Chair
Gary Shields. Treasurer

events. This body has also mandated compulsory "Black Box" warnings to be
included in ail packaging containing Finasteride.
Challetyges:
Securing repeat funding from a donor base that is largely financially compromised, and
baiancing r4)id projeet initiation with prudent reserves management.
On-going dialogue with the MHRA to obtain recognition and rep)rting of lived patient
experiences when they follow nationa15v #pproved guidelines and instn]ctions.
5. Financial Review
Total in¢omiDg resou￿ £30.902
Total resources expended: £27.261
Net movement ID funds: £3.641
Cash funds ¢arried fonv4rd: £3,641
Reserve5 Policy:
Trusices aim io hold unrestriried reserves equivalerkt lo approximately 12 months of running
costs (c. £1,000). As at l August 20?4: free reserves st(bod at £1,618. R¢stricted start-up
funds havc provided additional flexibility.
Principal Funding Sources:
Individual donations, raised on the widerstanding that donors will noi be placed in financial
hardship by their contributions.
6. Plans for Future Periods
l. Diversify FundiDg Base: Target corporate donors, private philanthropic foundations
and government grani programmes.
2. Patient Database Project: Se¢ure corc funding to develop a comprehensive patient
registry to identify sympiom-profile pattems and potential biomarkers.
3. Digital Outreach: Launch a YouTube channel to setve as an accessible inforniation
hub for PFS and PSSD communities.
4. Political Engagement: Lobby key MPS and fom) a cross-party. group to influen¢e
men s and young people's health policy, enhancing submigsions to regulators and
scientific nomenclature bodies.
7. Trustee Responsibilities Statement
The Trustees (who also act as Directors for company law purposes) are responsible for
preparing this report and the financial statements in accordance with applicable law and
United Kingdom A¢¢ounting Standards (FRS 102). They must:
l. S¢lect and apply suitable acwunting policies consistently.

3. Objectives, Public Benefit and Activities
Charitsble Objects:
To promote scientific research inlo the prevenliory cure, manogement and all¢viation of
iatrogenic diSeaS￿1ncludIllg, but not limited to, Post-FinasterÉde Syndrome-by providing
funding on the condition that useful research results are disseminated for public benefit.
Publi¢ Benefit:
The truste¢s ¢onfirni that they have had du¢ regard to the Charity Commission's publi¢
benefit guidance in plas)ning and delivering activtties during the reporting period. By funding
indeperhden( scientific res¢8rch. raisingT awareness among healthcare professionals and the
wider public, and facilitaling improved adver3e- effect retK>rting. the ¢￿tY has:
Advanced und¢￿tanding of PFSIPSSD pathophysiology, benefiting curr¢nt and future
patienLq through peer-reviewed publications and data-sharing networks.
Improved patient outcomes by disseminaiing p￿11¢2[ infonnalion and resources.
leading to earlier recognition and management of adverse effects by clinicians.
Enhan¢ed regulatory safeguards by collaboraiing with the MHRA to refine adverse-
event reporting workflows, reducing tht risk of under-reporting and safeguarding
public health.
Aetivities during S June 2023- 1 August 2024:
Fundraising: Raised £30.902 in donations predominantly from patients and family
members.
Grant-making: Committed approximately £24,0(K) to fund Professor Melcangi's
'Milano Project" at the University of Milan, a seven-investigalion initiative
translating preclinical PFS findings toward human trials.
S¢ientific ETrgagement: Searched for and screened additional resear¢het3 to
investigate underlying mechanisms of PFS and Post-SSRI S¢xual Dysfun¢tion
(PSSDI.
Awareness attd Advocacy:
Orcheslrat¢d'fv, radio and press interviews to highlight the scale 2nd severity
of fin&8teride side-effects.
Engaged the MHRA to improve adverse-eff¢¢t ￿pOrting accuracy and
timeliness.
4. Achievements and Performance
Research Funding: Enablf>J acceleration of two ongoing and five new clinical-
translational studies within the Milano Proje¢L targeting completion of illVf3tigations
by end-2026.
St*keholder Collaboration: Established dat&sharing frameworks with UniveT5ity of
Milan and initiated discussions With UK research partheTS for parallel siudies.
Public Aw8reiies5: Secured multiple media r￿tUreS. reaching an estim&ted audience
of over 250,000 and improving professional awar¢ness among healthcare providers.
Regulatory Engagement: Md with MHRA representatives twice, rcsulting in
revised guidan¢e for health¢are profe55ionals on re¢ording and TfWrtiE]g PFSIPSSD

Sidefxhub.UK
Trustees, ADnual Report for the perind ending l Allgust 2024
{Period: S June 2023 to l Augllst 2024)
l. Reference and Administrative Details
Ch•rity name: Sidefxhub.UK
Registered cbarity Dwtnber: 1203385
Registered otrice: 66 Leam Terrace, Leamington Sw CV31 I BQ
Tru$teo8 who servwl during the period:
l. Cjary Shield5 {Treasurer)
2. Katharine Hayden (Scientific oificer)
3. Bernard Morlet (Chair)
4. Robert Dixon
(All Inutee appoinlmenls arepatient- or beneficiary-led, or involvefamily members
ofpalienls. recruil¥d by invilalion.)
Board of Directors:
l. Gary Shields
2. Morten Skov
3. Robert Dixon
4. Bernard Morlet
(Pulient- orfumily-member-led, ￿￿elIng ui leasl weekly with daily communication
needed.)
Key advisers:
IDdependeDt Examijber: Max RetallacL TC Group Business Advisors &
Accountants
Bankers:
The cl￿peratIve Bank Community Dirwt Plus Account (online)
WISE Foreign Currency Account {online)
2. Structure, Governance and Management
Sidefxhub.UK is constituted as a Charhtable Incorporated Organisation (CIO) under English
law. Overall wntrol is vested in the Board of Trustee5. who set strdtegic direction and
oversee governance. Day-to-day decision-making is delegated to a patient-led Iloard of
Directors. which meets weekl). (with continual daily liaison) io manage operations and put
the trustees, policies into practic¢. A forn￿1 risk-register is maintsined and reviewed
quarterly, covering financial stability, safeguardin& and regUla￿ry compliance.

Notes lo the accounts for the period ended I" August 2024
l. Aecounting policies
{a) Basis of pre￿￿￿tiO
The financial Stslem¢nts have been prepared in accordance with the Charities Act 2011,
J¢counting and reporting by charities= Statement of Recommended Prdctice applicable to
charities preparing their accounts in accordance with the Financial Reporting Siandard
applicable in the UK and Republic of Ireland (FRS 102) (effective I st October 2019) (Charity
SORP FRS 102) and the Financial Re￿rtirtg Standard applirable in the UK and Republic of
Ir¢land (FRS 102}.
Sidefxhub meets the definition of a public benefit entity under FRS 102. Assets and liabilities
are initially recognised at hisioriial cost or trdnsa¢lion value unle55 Qtherwise ststed in the
relevant accounting policy note.
The financial statements prepared on a going ¢oncem basis under the historical cosi
¢onvention. modified io include certain items at tair value. The financial statements are
prcsented in sterling whi¢h is the functional ¢UTrency of the charity and rounded to the
nearest £1.
(b) Prep*r*tlOD of accounts on a going coucerll basis
The Trustees consider that the principal uncertainty regarding going concern relates to the
ability lo rai%e funds. The Trusiees monitor fund raising results and expenditure (a¢tual and
for¢c&8t) to mitigate that risk.
(c) Volunteers
The value ot s¢rvices provided by volunieer5 has not been included.
(d) Income
Income is included when rec¢iv&ble. Where income has conditions attached to it. that income
is recognised when there is c¢rtJinty of receipL entiilement and the amount can be measur
with sufficient reliability. Income (including granis receivable) is deferred where ¢onditions
exist on entitlement such &s a specified future time period.
{e) Expenditure
Expenditure is recognised in the period in which it is incurred and includes atiributsble VAT
whi¢h cannot be r¢covered. Expenditure is recognised when a legal or constructive obligation
arises. Costs of raising funds are those Costs IncU￿ed in attracting voluntary incotne.
Govemance costs are those costs incurred in th¢ &Fovernan¢¢ of the charity and its &ssets and
primarily associated with constitutional and statutory requirements.

BalaDee Shee¢
As at l August 2024
Notrs
2024
Current Assets
Cash at bank and in hand
Totsl CurreD¢ Assets
3,641
Otber debtors
Pr¢paymeDts
Current Liabilities
Totsl Assets le&s c￿rrent Liabilities
3,641
Net A55ets
3.641
Reseryes
UnrL%tricted reserves
Restricted reserves
1,637
2,000
Totsl Rese￿¢$
3.1kn41
Apprnved by the Trustees OD Date
sigDed on their behalf by:
Trustee

Ststemettt of Financi41 Aetivities
Income & ExpeDditure
For the
riod ended l Au
ust 2024
Ilnre5trir*ed
furlds
Restrirted
f￿rtd$
TotAI funds
to th¢
nearest
lo the negrest
to tht nearest
Al Receipts
UiQ dortdiions in GBIJ
UK donations itt kind in GBP
256
256
Ntsn-UK donalions in GBP
Bank Inierest
Non-llk Ih)naiions in b.uros
27.82 (GBP equivdni
Smb irt&1(Gr￿S iMcomeforAIU
24
24
2S642
5360
30,￿2
Tothl recelpts
2&642
$260
30.902
A3 PaymtntS
i.'r & Computing
3.194
3,194
Donations & (irants
24.1
Batjk f¢¢s
43
Pjiymcnt proce&5ing fees
Z4
Sub ith
37
27361
24,024
3337
27
61
Ne1olrec￿1P￿lW*tsj
1,618
2.02J
A5 Tr*u$f¢rs between fyttds
A6 CAsh fuudslost yur eHd
1.618
2,023
3th41

IDdependent Examiner'sl Auditor's Re
OD 8c¢ounts for the perl(
1° AUg￿l 2024
¢Dded
ort to the Trustees of Sidefxhub.UK
Ch•rity Ro
1203385
Set out on pages
Ito5
I report to the tru5teas on my exwninxtion of the accounts of the &ix)ve clthrity ("th¢
Trust.) for the F¢riod ended 01108n024.
RespoD$lbtutl¢8 #ttd bas15 of As the charity tn]str£5 of the Tn￿. you are responsible forth¢ pryaration of the
report accounts in ¥cordance with the requirements of the Cbarities A¢t 2011 fthe Act").
I report in Tesp¢d of my examinatioft of the Trust's accounts carried out under
section 145 of the 2011 Act and in carrying out my examinatio￿ I have followed the
appli¢abl¢ Directions given by the Charity Commission under section 145(5Xb) of
the Act.
I have completed my ¢xamina¢ion. I confirni that no material matters have Come to
my attention in connection with the ¢xamin&tion which gives me cause to believe
in, any material r¢spe¢t:
accounting records were not kept in accordance with wtion 130 of the Act
or
the accounts do not accord with the accotmting records
Independent examiDerfs
statsment
I have no concems and have com¢ across no other matters in conne￿10n with the
examination to which artentioD should be drawn in order to ¢nabl¢ a proper
understandkng of ihe a¢eounts to be reached.
Slgn¢d:
DAte:
20 May 2025
Namv.
Max Retsllack
Relev4Dt professiottal
qu811f￿all0n(5) or body (If
any):
FCCA
Addresj:
Nelson House. 2 Hamilton Terrace,
Learnington Sp4 Warwi¢kshire
CV32 4LY