Rb:Glb'l'KRkD CIIARII'Y NUMBLR: 1191179 Farri¢s Kirk & M¢V¢an Hcathhall DIJMfKILSSIIIRL DGI 3SJ
for thé YoAr Endtd 31st Jul 2025 1>gge Repor* of th• Tru$¢¢¢s Indgp¢nd¢llt ExAmillcr'J Report StAt¢mEfbt Dr Finn¢lA1 Actlvltles Sheot Notes to the Finllncial Statements Det•ll¢rt StAt¢m¢nt of iiln#oel41 Actlvltlos io
rt of the Tyustees ror tlie Year En(led 31st Jul 2025 Thc Irustecs prrnI ilicir report with th¢ fiiiaiicial sla¢em¢nts of Ilie chariLy for the yeai. ended 3151 July 202$. Thc IrusicL.I have dopted thc provisions of Argounling and Rcporting by ChgritiC5.' Sialctncnl of Rccomrncnd¢d Pravlicl Appli¢8bl¢ io ¢hurili¢s preparing ihttlr ttctout)1s In accordllnLe wilh the Finonci&l Reporting Slandard ttpplieable in the UK and Republic Qr Ir¢laiid (FR% 1021 Icrrcclivc l January 2019}. OBJkC1'1VES ANI) ACTIVITIES ObjtctivtB fLnd 91ms Th¢ ubj¢¢iiv¢b ofihc CIO are thc r£liefofsickiiess and the pi'eservaiion of Iiclllth. in particular bul not cxclusively by-. la) Iljc rcliofind tre4im¢nl of pcuplc wilh Spinal Mu5Gular Airophyy Ibl Ilic promotion ld support of rcsettrLh inlo Ihc Cause. Irculment #Ad possibl¢ pr¢v¢niioii of Spiii&l Muscular Atrophy ond the publi¢aiior) and dis5eminaiion ef tl)at rc%carch for ilie public bellcfit., and (¢1 Ihe odvonccinont ofih¢ ¢du¢uilon ofihc g¢n¢ial publi¢ in Spinal Musrular Atrophy. Public benefit Launch uf w¢b5il¥ and donation rncch4nis Ilegul social Media ¢iigag¢menl Variou¥ cv¢nlb aciivilies io raise funds, .e.8. charity walk. coffcc mornin8& painiiJtB auction -rh¢ firsi &¢livity the charity l5 SUPPQrtin8 ix clinical rcscarch wilh rcgRrd5 Ihc objc¢livc ofthr EhaFiIy ACIIIF.Vb MF,NTS AND PF.RFORMANCE CliaritAblt ACtivlti¢$ As Iw51ces ofACE SMA, wc Thrc pleased to present the annuol rcport and finuncial 5totemcn15 foi Ihe ycaT crJd¢d 2023. This r¢pori providcs an ovcrvicw ofihc chariLYs &cVille$, achievcments. flnanci pcrformancc, and fulurc plLn5. Thc charity'5 purpo.%c is ID huild an Aivfftreiiess, h¢lp fiiiid a ¢ur¢ olld help iiiiplciiicnl cxcrci%c aiid pliy510thcrapy for rhildTcn wid) SMA. ThL tru51LL5 have mttd¢ signiflcant pi'ogresy low.d5 achicvittg Ihcsc objectivc8 ovcr Ihc pa51 ycar wilh Ili¢ conliiiue(I foius on rundi118 tlie ACI:. 8MA pliysioiliLrApy Llinical trial lviih Tli¢ Univ¢rsiiy ofoxford, lli¢ Iii8lilight% of illi3 aciivity have bccn- Rcctuit 14 participDnt% for the ALI.: SMA phy.8ioiherupy I rial All fainiliLs involvcd havc participaicd cnihusi851i¢dly and thttre h&ve bccn xcro dropoutb despite itt¢ r¢laiiv¢5y h¢ovy coniiiiitment iiivolvcd All futniliu huvc 5igncd up to ihc 6 tnonth extcnsion of thc trial thlli ACE SMA ho5 providcd Rdditionul fiindinR for Th¢ irial aAd its ¥xlensiOn Wtll provid¢ improvi longitLidinttl dilla Io suppori ll rnorc sigiiifi¢niil roll oJt ofthe project 10 furihcr cenirc% in tlic IJK. Grnni funding opportiiiiities are b¢i118 ¢xplored 10 support a Inu¢h larg¢r l)h&i£ 2 pi'ojcci. Th¢ ¢h&rtty ¢onllnu¢s ID cngagc with the SMA CDnimunity lo cxplorc furthcT arcn5 in which thr choTlty ¢ould bupport tn ih¢ fuiiir¢, INANLIAI. RfVIEW Fln•D¢lAI posltlon Tlic Charliy iai5cs funds to m¢el IL% c011511tulional objectives aiid tlie prcrvQt1on of li¢alth. DurSng th¢ p¢riod of th15 Iort th¢ Cliurity Iii¢iirr¢d M detl¢ll of£16,763 (2024 - £137,981) from 115 actlvltlcs artd at lh¥ ¥nd of lh¢ period lh¢ Cliarity had ioial r¢%erv¢8 of £20,43912024. £37.202). all of which is uiir¢stri¢tcd. Expenditure.. The ¢li&rlly htts m#inl8incd rt focu5 on ¢nsuiinE thai ¢Xp¢ndiI all5 wilh i15 charilable oblecilves. Prineipil fyndlng 50ur¢¢g Th¢ charilgs sn¢onJc is primarily dcrived froin donations ond fundrailiiig events. Notably. it rcceivcd significant fundiug ftorn & lllrke Plirty in M&y 2024, whicl) cnabled It to fund ihe extenslon of the study. RLY¢rv¢i poll¢y ACE SMA has a pollcy ofkeeping sufficient rLs¢rves lo support It5 ongoing aciivily for a¢ l¢osi ooe ytrtr. IIUTURE PLANS Looklng forword. lh¢ churily aitns 10 build on thc suGc¢s¥C5 oftli¥ pllsi y¢ur dnd foGus on lh¢ following key oroos.. Aidin8 Thc Ilniveriiiy of Oxford iii srcuriiis nIs for Ihe lurger Pliose 2 irial Und¢riak¢ g ¥rLdlLr nunibcr of smallei. fuiid raisin8 activities insleod of focu%in8 011 onc lar8c fund raising party t3uild Ihore Awur¥n¢s5 for SMA ihrough rcgulHT tncdia opportunilic5 and Ivh¢J) thcy uri5¢ 4 Pind an aiiibailador lor ACE SMA In a wlieLlchJir llihlet¢. W¢ ar¢ comjniltcd lo huildi1i8 AwaEne53. h¢lp fuiidiiig n ¢ur¢ uiid impoiionily inipleincniin8 exerci%c and physioihcr&py for childrcn with SMA and will ¢onlinu¢ working with our 5UPPQrtcrs, bcncliciarir5, und partncib lo furthcr OUT Itnpii¥l, STItUCTURE. GOVERNATr4CEAND MANAGEMENT Governing docuinent Th¢ cliarity is ¢onimllcd by It% gtsvemiiig documeiil, & deed oftru51 ond conslilules uniiicorporthd Ghariry. R¢¢rwltm¢nt And appointment of new trustees I'rust¢¢s hove be¢rt re¢ruii¢d by th¢ foundeis ol Ihc ch4Lrity. Therc is an annud5 TfVi¥iV prtr¥¥ss in Iln¥ wilh ¢h¢ wnsiilulion. Puge I
r Eindod31st.lu REFERENCE AND ADMINISTRATIVE DE'I'AILS R¢gistrr¢d Charity number Principnl llddress Gl¢b¢ Coii&g¢ Suitoii Mand¢ville Salisbury SP3 SNA TruJt¢¢J M l.lowe5 C11ainnan Mr5 C A E O'Hora Mrs A Fl Wheailcy-Hubbard MTh S l.lowes Ms R 11 CiUttSI O C L William¥ Independent Exomintr David Miicliell, CA rartl¥s Kirk & Mcvcan Durtifrl¢s lirJtei'pris¢ Pork DumFri¥s OUMI".RILS%I.IIIiE DGI 3SJ Approved by order ofuie bogrd oftrusi¢¢s on 5th Jthnuury 2026 ind si8nod on Its behalf by.. M [10.0.- Trus Pa8e 2
r'5 Re Independent eximlnir'j r¢por¢ to tho trust¢¢J ofAC& SMA I report lo the thorlty truSeS on my oxaminatlon of the accounts ofACE SMA (tho Trust) for thc year endcd 3151 July 2025. R¢5PDll5ibili¢i¢5 and b451¥ of report As Ihe charlty ¢rusLe¢.¢ ol'tlio Trust yoy ar¢ respon$ible for ilic preparatlon of lh¢ oc¢ounts ltt accordancc with Ihc rcquircm¢nts' of Ihe Ch81'itic& Acl 2011 ('thc Act). I report In respect of my exwhinAtioii of tho 'fru$t's a¢¢out)ts t#rrl¢d out under Stctlon 145 of thc Aci in c&rrying oul my exaniinaiion I havc followcd all applicabl£ Dircclion5 8ivcn by Ili¢ Charily Cornmlssion under Se¢iion 14515llbl of the Au. IndopoNdint eximln¢r's itllemtnt I hdvc complctcd my cxami118Lion. I coiifjrm 1112L no n)ateriai rnaiicrs have comc lo rny ultcntion in ¢onn¢¢¢ion willi Ilie cxwnin)iion giving ni¢ ¢aus¢ 10 b¥licwe thai in any matcrial resp¢¢i'. accollnlin8 rccord5 wcre not kept In rcspecL of thc Trust as rcquircd by Scclion 130 ofthe A¢i,' or Ilic a¢¢ounts do noi t)¢Lord wilh thobb records., or Ihc uc¢ouiiLs do nol comply wilh the gpplicable requirement5 cots¢¢ming th¢ form wid ¢ODt¢ni of #¢¢ounl¥ 5¢L out in th Churitics IAceounLS and Reports) IlcBul2tions 2008 oth¢i' Ui&n any rcquircmcnl Ihal th¢ aiiouiiis giv¢ a Irue And fair vicw wliieli is iiot li moii¥r ¢onsid¢r¢d lls p&wI ofAn ind¢p¢iiiJ¢nt ¢xami11o1inn. I hov¥ no con¢¥rns and hAv¢ cvmtt across no olli¥r muii¢fb in ¢onii¢¢iioii willi tli¢ ¢xarninoilon to whicli atlcntion should bc drown in Ihi% iTport in ordcr 10 enable L prop¢r uiidersigiidin8 of Ihc aceoun15 10 bc rcaclicd. D)vid Mii¢liell. LIA. CA FaLT1¥5 Klrk & Mcvcan l)umfric5 llnterprisc l)srk 14¢oihh411 Duinlrics DIIMFRIESSI-IIRI:. DGI 351 5th January 2026 Po8¢ 3
Stntement of Firtnncinl Activitie5 for the YeAr Féndcd 31st Jul 2025 2025 Unrc51riclcd rund 2024 Total nds No*s INCOME AND ENDOWMENTS fiROP¥l DolltionS and le841¢5 33,190 5,680 Oih¢r Iradlng aeiivitics ltsv¢stment lrtcoine 44,331 220 8,496 Totgl 77.741 XPLNDITURE ON Rlising fund¥ 24.438 174 ChAritgblt nctivitie$ ACC SMA 70,633 152,798 To¢il 95.071 152,972 NET INCOMLllkXPETr4DITUREI 117.3301 (137,981) RECONCILIATION OF FUNDS Total funds biou8lit forward 37,202 175,183 TOTAL FUNDS CARRIED FORWARD 19.872 37,202 Thc nolcs forjn part of Ihcsc financial 51atctncnt5 Pa8¢ 4
Balnnce Sheet 31st JUS 2025 2025 Unro51ricted Ind 2024 fund NoiE5 CURRENT ASSETS D¢biors Prepaymcnts and accrucd incom¢ Lash ui bink 126 573 2.340 33,249 20,196 20,322 38,162 CRFDITORS Amounis Folling due wiihin oiie year 14501 (960) NET CURRENT ASSETS 19,872 37,202 TOTAL ASSETS LESS CURRENT LIABILIT114S 19,872 37,202 NET ASSETS 19,872 37,202 FUNDS UnTCgtriclcd fund 19.872 37,21)2 TOTAL VUNDS 19,872 37,202 Thc financial SLileiKents were approved by the 13oard of Trusi¢e5 and Authori.%ed (or issue on 5th January 2026 and iverr si8ncd on its bchaifby.. M FIoiYe5-'frusree The notes fomi pRrt of thow finmeiol stslt¢moiiLq P#ge S
Notes to tlle Finnrttiml StMtsmtntS foi. tlie Yenr Endcd 31st Jul 202.1 ACCOUNTING POLICIKS Ilijli of prop#rrng the fJnllnciAI Jtitement5 'rh¢ finJn¢ial sLAtements of ihc ChritY, wliich is o public beneni enlity undor fRS 102, hovc be¢rt preparod in accordance with ilic Chariiics SORP Ib'R8 102}'Accouiiiin8 and Reportin8 by Chariiic.i'. StalLiiicni of RccoinmLnded Pracii¢L uppliciibl¢ 10 ¢hariliL¥ pr¥paTill¥ thcir &ccounls in akcordancc with Ilic financlal Reporting Siandard appli¢able in tlie IIK ond Rcpublic tsf Ireland IFRS 1021 leffectiv¢ l January 20191,, 1'.inaticifjl Reponing Siaiidwd 102 'Tlit Financial Reportittg sLdard pplicablc in ihe UK and Jiepubli¢ of Ir¢ltsnd' and th¢ Ch111¢5 Act 2011. Thc fiiianttial statcmcn15 liavc bcen prLp8rcd under lh¢ Iiislo¥i¢&l cost convcnlion. Incom¢ All inLornc is rcccsnised in tlic Slaleincni of l.'inancial Aciiviiics oncc thc cliarily has cnliilcrnrnl to lh¢ n8, il 1$ probabl¢ that Ilio income will b¢ r¢c¢iv¢d Ind lh¢ mount ¢iin b¢ meJsiir¢d r¢liubly. Expenditure LiNbili11¢5 Ure Ircogniscd cxpcnditurc a5 500n a5 Ihcrc 13 a Icgul or conslTU¢iiV¢ obligaiion cDinmitiin8 Ilic cliariiy to that expeiiditur¢, it is prob&ble Ihai IrJnsf¢r of economic benclils wlll be requir¢d ill SeLileiDciit and thc amouni of thc obligation can bc measured rcliahly. l.:Kpciidilurc is accouiiled for on an acci'uals basi5 and hgs brrn ¢l&bsifi¢d linder headings Ih&i g8r¢gJt¢ all rclalcd lo Ihc c&tcgory. Whcrc cos15 cgnnol bc diireily tttlribut¢d to partic11 h¢lldings they li&ve b¢¢n allocaitd 10 octivilits on a basis con5isILnt with the use ofresoiirces. (yranis olf¢r¢d subj¢ci lo condilion5 which havc not bccn m¢1 ai ihc y¢ur ¢nd dAl¢ ar¢ nol¢d as o ¢oinmi(mcnt but not accrucd as cxpenditure. Tix*tiDn I'he Chorlty 15 ¢x¢inpl from IX on Ils ¢haril&bl¢ N¥liviti¢% Fund Ac¢ountlng Uni¥siTirlcd fulld5 can bc used In oecoTdance wsih tlie chwitable objcctlvcs al thc disrr¢tlr>n ofih¢ ¢ru31ce5. 5PCCTficd by tlie donor or ivlieii fundg arc roiscd for paniculur rc5trielcd purpo%cs. rurth¢i ¢xplunation ofihe nalurc purposc ofrach fund is in¢Sud¥d in the not¢s io tlie finaiicial staicmcnts. OTHER TRADING ACTIVJ'I'KES 2025 2024 Fundraising ¢vttntS 44,331 8,496 INVESTMEIYT INCOME 2025 202A Dcpoyit coUl71 inter&st 220 815 TRUSTEE5' REMUNERATION AND BENEFITS There wcrc no trustees, remuneration or otlicr bcncfits for thc ycar cndcd 315t July 2025 nor for Ihe year ¢iid¢d 31.%t July 2024, 'frus¢¢ts' ¢xp¢rt$os Th¢re w¢r¢ no Irust¢¢¥' CXPCll5¢5 pDid for thc Y¢ dEd 3151 July 2025 nor for lh¢ y¢&r ¥nd¥d 315l July 2024. Pag¢ 6 oonlinued..
NotQS to the FinAnti*l StAttmtnt for the Year Endcd 315t COMPARA TIVES FOR TIIE STATEMENT OF FINANCIAL ACTIVITIES Unresiricicd rvnd INCOME AND ENDOWMENTS FROM Donaiioii¥ and l¢¥a¢iL¥ 5.680 Oihcr tradin8 activilies Inv¢siin¢nt in¢Dmc 11.496 Total 14,991 EXPENDITURE ON ai.gin8 fvnds 174 Charltllblo actlvltles ACE 8MA 152.798 TotDI 132.972 NKT INCOMFIIEXPENDITURL) 1137,981) RECONCILIATION OTr FUNDS 'I'otal fui)d% brouglit forward 175,18J TOTAL FUIYDS CARRIED FORWARD 37,202 DLBI'OIIS: AMOUNTS VALLINC DIIK WITIIIN ONK YXAR 2025 2024 VAT 126 573 CREDITORS.. AMOUNTS FALLING Dub WITIIIN ONE YEAR 2025 2024 Oih¢T crcditDrs 450 960 MOVEMLN'f IN FUNDS N¢t mov¢meiii in fund5 At 31.7.25 Ai l.8,24 Uijvostrlctod fuKds Gcneral fund 37,202 117,3301 19,872 TOTAL TrUNDS 37,202 117,3301 19,872 P#g¢ 7 ¢onlinued..
ACESMA MOVEMENT IN FUNDS- continued Ncl movcmenl in fund4 includ¢d i# Il)¢ abov¢ Ar¢ as follows.. Inoom5ng r¢sour¢e.q R¢>oiirL¢Y expeiided Mov¢m¢nt Unrtstrlttod fund$ Gcncral fund 77,741 195,0711 117,330) TOTAL WUPIDS 77.741 195.0711 117,3301 Comp4rRtlv¢s for movoni¢nt in fund5 N¢t mov¥inent in fund3 At 31.7.24 Al 1.8.23 Unrestrlcted fvnds G¢n¢rnl fund 175,183 1137,9811 37,202 TOTAL FUNDS 175,183 1137.9811 37,202 Coinporoiive rtei movemrnl in fund5. includcd in the abuvc arc as follows.. Incoming rewiiries Re50urcc5 ¢xp¢iid¢d Movemcnl Unrestrltted furtdy Cieii¢rg1 fund 14.991 (152,972} 1137,9811 TOTAL FUNDS 1152,9721 1137,9811 A currcnl ycar 12 moiilhs and prior y¢ar 12 Inonths ¢omblncd posiiion is as ftsllows.. Nel moveiiient in funds At 31.7.25 Ai 1.8.23 Unrestricted funds OEncral fund 175.183 19,872 TOTAL FUNDS 175,183 19.$72 A current year 12 moiiihs Thd priur yellr 12 month5 combined nei mov¢mertl in fund¥ Included in Ilie abov¢ nre os follows.. Incotning Tcboufc¢5 Rc¥oiiri¢s ¢xp¢nd¢d Mov¥m¢HI Unrr5tri¢led funds GenLrul funtl 92.732 1248.0431 TOTAL IfuNDS 92,732 1248,0431 Page B
t(k thts FingnciAI StntomEnts- co for the YtAr Elldtd 31st Jlll 202S RFLATCI D PARTY DISCLOSURES Therc werc no rclatcd party tsw)saciions for tile year ended 31s1 July 2025. Pllsc 9
Detnlled Sthtement of Finll for the YEnr End d Jlst Jul 202S 2025 2024 INCOME AND ENDOWMENTS Donatltsns And IcgAeloJ Donation5 33,190 5.68 Other tr4dlng A¢t5vitieJ Fundr$18 tvent% 44.331 8.496 Investment Irseomo DLposii a¢couni int¢rest 220 815 To¢41 InmIng rwourrts 77,741 EXPENDITURE RM151n£ doDntlQll$ And IEgwei¢5 Sundri¢s Evcnl c051s 174 24.438 24,431 174 Charitable nctivitiP5 300 292 66 Advcrtisin8 Sundric5 Web5il¢ CeSI ciivin8.com f¢¢ Givcrgy Granis ¢0 ih51ilUliunb 555 50d 209 315 1,395 150.000 68,597 70,165 152,284 Support eo$ts Bank ch8r8CS 18 34 Govorn#nEo rojts A¢¢ounioncy feeb 450 480 Total r¢3ouw¢s ¢xp¢nd¢d 95.071 152,972 Net exptnditure 117,3301 1137,9811 This p88c dDes not form part of th¢ $toiutory fingn¢i41 statements PAg¢ 10