KW Unaudited Financial Statements Isla Rose Foundation Forthe year ended 31 January 2024 Prepared by x1rlK0d Wttson Lbmlted
KW Contents Tntstees Report Trnstees IntlependentExaminerf5 Report In¢ome&EypenditureA(count Balance Sheet P4112¢¢8
KW Trustees Report Isla Rose Foundation Forthe yearended 31 January 2024 Isla Rose FoUndatSon-Yeartyula1e(Io24} M•kiry• DiffereTrteTethe1 We'réthrilled tosharethe Isia Rose Foundatlon'$¥hlvwnentsthisyeart K•ykhI•vntslTr2Q2&. FundkngR•s•arth. We maJeasignifiCantntrib10n of£3}10 supportvital NKH research atVCI London. SupportiTri Famili:Wedirertiy impacted ajwngyrt's bfe tyfundingthree monthsof specialised therapyforsoffa, battllngNKH. F¥ndrnisin¥Sucus5: Despite a challenging eronDmic dlrnate.theSwthFCornMUlYtyar wpportws beYOr have rallled behirrfl u5. Wee successfully rai5edlund5through IrKal and natlonal pre55co¥erage.alongsTrdeheartwamiin8community lundraisingevents. Ral4n¢AreMU. Sodal media continvesto be a powwlultr)L Byshartng our joumey, ¥R'Ve8n1fiCantinCw¢ased awar¢ne55 of NKH'S rarityand 8amered imialu4blesUPPtytfromtheidercommunity. Ourwslon: A cure for NKH remains oyrultirnate goaL We'll conty"nueto empower NKH famlliesfy proYfdlngatte55toequipmentand theTrpies not readityavaiiablethroughthe NHS. uhlmatelyimprovingthelrquabtyof ble. Gene therapy research Ung mice rnodels 15 dernon5tratinR%nIficant advancements, ofterfnga gilmmerof Wefgr Improved treatrnentol Non-KetotK trtyper8lycrnemia INKFII. This approach holds excitirEpotential for. InwUt•r• Trn•trn•nt Early intewvention crucial. and getherapY offerstherA)ssiknirtyoftreatlng NKH before birt potentially preventingthe severe complicationsofteTh a550Ck?ted wrth the disease. Extsnd¢d Llftspan%Currenttreatments managesyThptomsbutare Thot curatNe. Genetherapy hasthepotentialto addresStheundorngBenet1( causeTr polentialty leadingto a significant improvement in fe$Pan aThd o¥eTall we114>eing lor NKH patiffit& WINle research is still in pIL[In1£31 Stage4sd in mice mode15have proThusingrewtts: In¢r•asedActl¥lty of th• Fwhrllon•lEnzyme: Genetheropysucce55fuilyrntroducesa heahY copy of the affected ge. leading to the productim ofthe functionalenzyme respM&blÈ Forgtycine brÈakd¢>wn.Thi% diredy addressesthe core $5ue In NKH. ft•du¢•dGl1Th•L•ve1. Studies reporta &gnificarbtdecrease In8lyclnelweLs w)treaied mice, iDdlcatyngthe potentialto control thetOKiC buildup associated wrth thedisease. Impm¥•d N•Jrologi(•lFunrtion: Earty inter¥eniionthrouKh in4JteroEenetherapyhasshown prnme in theory ol preVentingtheSere neurolrycal cornplicationsoften seen in NKH patrents. whilefundralslngrema1nscompe14tsraUthlrf$stOryhas8ar¥ed Significant lrfaland national media attenikn, raising aarersS and ltalNI% Inthe fMj,we aTrt0 rEAtequipmenttotherapycentwes, wlth yoceed5 benefftingtheltsundatn. OpporbJnitiesYouTubethannelorincreasin8awenessof socwl media page& UrthudthdKnanth1Slateme Isk RoseFty*thtio PaKe34ro
KW OurFivtthye¥ G••ls." Secure rna¥imurn lundingto find acureforNKH. EmpowerNKH familieswth 8r3ntsfortherapy.eqUiprr•iL4ndessentialppDrl Increase research fundingat UCL Look intoopeninga bcal charityshoplpop upshoptrlaltl) potentsaltybringin c0nstantfundingsupportwlt)utSett1nl up actual event& V•lu•s Ind C•liabontio Collaboration i5at the heart ofowsuccesswevalw. Cornmunity 5UPPOrtand invOement fundrdi%inginiuati¥e& Seeklngprofe55ional freeKuidarKeto refineourEoaLs and ¥eseaffh effort ContiThuous learning and acommitmentto progres Supportingeveryoneattected byNKH-familie& $arthe arrtllurKlTri5e WÈ tsperate a dedlcated teamolvolunteerswho are pass)nate aboutourcause. Flh•tKi•lSustain•biiity: The ISLI Rose Foundation opeTrtes indedenttythr0lh owbsite. Ger{J$1nttÉrèCcOUIrtaThts manageouryearly accounts. Futsr• Plans: Our board otlrustres ffleets quartertytoreviv progress and stnteOraltypLin forthehJture. Weensure 04K actkins align wtn ouitorevalue5and elfectNdy rnanage any risk& We continue asa non profrtanddon'lcharge ewses. LkniudwFlni 5tteir•*% R&S•FdItsDTr
KW Trustees Isla Rose Foundation For the yearended 31 January 2024 The trustees are re4)wbleforihè managementof therisksfated bythecharrty. s.J. steel- Chair S J, Camey-Trnstte B•nk•rs NatWe5t8ank PLC 130 Lord Street, Southport PR9 QAE Ind•p¢ndentEx•mln•r I•¢1 Wilson rnited Unit2A.Swordfish Busit)essPart Burtough L4Q8JW Authoris on beha1f01theTnee5. Slgned.. Poy5ofJ
KW Independent Examiner's Report Isla Rose Foundation For the yearended 31 January 2024 IndependentExamlneVs R•porttothtrustee•ftheWa RoFwnd•tkn We reportonthÈ a¢¢ountsofthe Charityfortheyearended 31JarvJary2W44.whlch aye sLYOUtthi page$7and Resp¢¢tl¥e rsponsibilltiesvltru¥tW51nd •xarniner The charivstrustees areponsIbl¢fOTthe preparatfv)n oftheaccounts. Therity'strUStteseofisiderth4t an audlt Is not required f¢Hihisyear tsndèrsectiofi 144121 oltheCharitiesAct2011 lthe2011Actl and that an independentexamination is needed. It isoUrresForilltyt0= examinethe accounts undersectk)n 145ofthE 20LIA¢ . to foilowthe procethres laid dovth inthe8erral Direction5 given bythecharity Comm10n undersertion 14515llbl ofthe 2011 Act. and .to statewhetherpartiCLtlar matters havecomto our#ttention. 81sof Ind•p•ndont eufflin¢r's report Our examination was(aled out in accordancewlth thegoneral DlrÈctkn5 yven bythe Charrtycommission. knexamination Includu ? reviewofthe acwJntin8 recods kept bythÈ¢harttyand a comp0ri50n ofthe occouThts presented withthose records. Itaiso includes ColderatiOn of any unusualitemsordisdosures In the accounts, a15eeking explanationsfrom you astnJ5tees conceming5uch matters. The procedures undertakendo Mt provideall thedeThCe thatwouk4 be required in an audit and corwvently no opinion isgNen astoWhethertheaccrnts £fft a'tnjeand fèirvie ènd the reportis limited tothose matters setout in thestatement ltsw. Ind•pMd•rf•xamln•rfs st•tm•Nt ITh corbnection withourexamination, no mattorha5come toourattention: L whlch gives us reasonable causeto believethatin arymaierial re5pecttherequirementsto keepaccounting records In accordance with section 130 of the2011ki' and to pPare accountswith the accountiThg records and comply the accounting requirementsofthe 2011P£t have noi betn Met or I to which, in ouropinion. attention should bedrawn in onl@rto QbIta proper urthr5tandingofthe accountsto be reached. Indendent Ex•mlnqr gned.. KirlAvood knmlted Urrit24 SwordifLSh Bu5rne55 Parl Lancashire.L408JW PaEe6fjr1
KW Income & Expenditure Account Isla Rose Foundation For the year ended 31 January 2024 Incom• and (k)nafjvnsReceNed enditureAccount 30.545 Thiapy&EquipmentEpses Donation5 Made 110.X181 13,0001 17J36 TotallK•**ndEwthiurek£oi Un•udM Fkn¥KblStattwrt5 lthlb)F•FtywbYoiirKb PAy7of8
KW Balance Sheet Isla Rose Foundation Asat31 January2024 33¢2011 Assets (liabilities ASMtsi4ss curr•ntllabWti•5 Curr•Trtkjl TotalAs5•ts i•sscurrnniDabMld 24,925 24,925 TotslAssetsiiiabllt 24?25 Ca itsl and reserves T¢)tsl Pr•fft&L¢ss rrentYeaTEamings PmfitaDd IDssxcow)t TotalT•tsi PYofit&Lo$5 I76 24915 Toi*IGlWt•1drt$eS 24,925 Page8ofe