BIOTECHNOLOGY AND MEDICINE EDUCATION TRUST REPORT OF THE TRUSTEES AND FINANCIAL STATEMENTS FOR THE YEAR ENDED 31st MARCH 2025 REGISTERED CHARITY NO: No: 1165469 Registered Office 8 Madison Way, Sevenoaks, Kent TN13 3EF
Charlty No. 1165469 BIOTECHNOLOGY AND MEDICINE EDUCATION TRUST Thistees, Annual R•port for thè p•rlod from 1•t Aprll 2024 to 31•t March 2025 The Trustees {who are also the Dir8clorsl present their rowrt and the financial stat8rn&nts of Ihe ch8rltsblg Company for the year to 31" March 2025. Trust998 Th8 followlng have served as Trustees durlng the year. Ali Alidoust {appolnted November 2024) Sébastl6rs Farnaud Peter Gluckman Tanvlr Mlah (appolnted Msy 2025) Jenny Murray Arron Mungul (appolnlad Jun8 2024) Paul Nash (appointed Feb 2024) Russell Walters (resigned May 20251 R•gl•t•r•d Olfie•: To May 2025.. 8 Madison Way SevenoakG Kent TN13 3EF From May 2025.. To be confirmed Offlc•r• To May 2025.. Chalr and Treasurer- Ru66011 Walters From May 2025: Chair- lo be corrflmed Tre8SLYer- Tanvlr Mlah STRUCTURE GOVERNANCE AND MANAGEMENT The Blolechnology and Medicine Education Trust is a Registered Charity, No. 1165469. The Trvst becarne an incorporaled UK charity on 8th August 2016. adopting a Memorandurn and Articles as its governing documents. 11 acquired Unitad Stat8S 501lcP status Ihiou9h the Klng Baudouln Foundation In Septeml)er 2016. The Tnjst was established to enhance publi¢ understanding 8tK)Ut the pt)wer of biotechnology, Itfe s¢len¢e8, emerglng technology and high tech ervJineering to 8nhan¢e people's Ilves. The prlnclpal objectlves of the Trust are lo raise funds to SUPPOrt the actlvltles Ilke What19Biotechnology.org {WiBI. a non-profit website that provides onling educational resources about rocenl advances in biom6dic81 science for the benèfit of the general public, heafthcare workers and other key stskeholders. It Is also supporting the developmenl of free educational activities to en¢our8ge students to pursue careers in the life xience. technology and hlgh tech engineerfng se¢tors.
The Board of Trustees, which meets as qUId, is responsible for overall policy, strategic direction 8nd management of the Trust. In line with recommend8d practlce, Trustee appolntments are tim8 limited to three years altt)ough up to thrèe consecutlve temis may be served (then subject to a break of al least one year). In seeking new Trustees, consideration is given to the balan(t of skills, experience and knowledge that the Trust requires. New Tru5tee5 are made aware of their stalutory dulles a6 Trustees and of thg nged to wmply with relevant Charity Commission guidancè. Th8y are also invited to find out about the Trust and the work of the Board by talking lo and working closely with other Truste85 and are strongly encouraged to undertake approprlats training when they loin, and throughout thelr mg on the Board. ACTIVITIES WhatlsBlot•chnology.org: 18 bulFt around content on the webslte which conllnues to altract large ajIenC6s, rW gettlng over 2.5 million page vlewlng5 per year from school and university Students. health care professionals, Induslry experts and the general public around the workl. The website's dynamic plattomi provides scope to add mat6rlal very qUiGkly in tandem wlth scientific developments as they unfold. Thls indudes a searchat48 IlmelSne whlch18 regularly updated as 8v8nls unfohj. It now h08 2,750 events. 2.2. An inwdeplh Intervlew wlth Professor Simon Gordon was Post on lh8 websit8 Sn October 2024. In his interniew. Gordon talks about his earty Ilfe in South Africa and how h8 became interested In macrophages while a dtOr&I student al the Rockefeller Unlversity In N8w yo. whlch he contlnued to Invesllgate when h8 101rd the Dunn School of PaltrK*logy at Oxford Unlverslty. HIS Intenibew hlghllghts the challenge8 of research In the 8rea and the many roles macrophages play In the body including In the d8velopment of cancer. Gordon also talks about how he gol Involved in the development of a cartoon booklet lo help educat8 school 8tudents in South AfrirA to protect themselve• agalnst HIV at a time when there were no anllrelrovira18 lor the disease and no ¥acdn6s. Three now In4epth sclenllllc profi168 We added to the webslte over the year. The first looks at 3D Genomlcs. Bullt on the bad( of the Human Genome Prohocl and other 18chnologlc81 advancès mado slnce then, 3D genomlc8 Is openlng up new Inslghts Snto the spatial org8nisalion of the genome which were previously impenetrablo. Critically it provldes a means lo Investlgate h¢)w genes Interact wlth regulatory elements even when a conslderable way 8P8rt. While the technology is stlll In Its infancy, 3D genomics is already offering new insights into cancer and other complex diseases like multlple sclerosls and rheumatoid arthritis, thereby opening up Fjotential rffiv therap8Uti¢ larggts 8nd the development of more effective and personalised medicSne. It has also shown strong pot8nllal for Identlfylng new therapeutlc uses for exlsting drugs already marketed for other conditions. A Send science profil8 posled online provides an overview of the evolution and Importance of immunoassay diagnostics. Deslgned to exploit the blnding reactlon beeen an antlgen and antibody, immunoassays make it PQS5ible to detect and measure specific substancés in biological samples. such 9$ blood and other bodily flulds. Used extensivety in hospit818, laboratorl8s and research centres slnc8 the late
nlnet88nth céntury, immunoassay diagnostics are invaluable tools for the detection of Infectious disease5 as well as for many non-communicable diseases. Jusl how valuable they are was seen dudng the COVID pandemic when Immunoassay diagnostics w8re used on a wide scale for self-lesting. This was helped ty the fact that such diagnost1 are simple to use, inexpensfve. accurate and fast and can detect very low levels of infection. As well as b8lng used for dlagnosing disease and rnonitoring treatment, immunoassays are pivotal to biopharrnaceutical research and development and for the detection of envlronmental hazards. The thlrd sdenllfi¢ profib covers the hlstory of GLP-1 drugs which have surged in popularity in recent years by vlrtue of their ability to help with obesity. First approved for obesity In 2021, the d8velopment of such drugs did not happen overnlght. Nor was ob8slty their startirvJ point. As th8 profile mskes clear, thelr 8m8rgenc8 rested on the long quest of many different Individuals over many decades to unravel the compléx physiology of th8 gut and its dlsea5es, partilarlY di?beles. Progre88 on thls front w88 incremental and ti)ok many Iw18ts arvj tums. Demand for such drugs Is Ilkely to continu8 to be strong In the future due lo rislng rales of obesity and Interllnked chronlc disea8e8. GLP-1 drugs alr88dy show promise for the treatment of many Inflammatory dlse8ses including Oslhma and inftammatory bowel disorders like Crohn's dlse8se and ulcerative colitls. During the y8ar effort5 have contlnued to roll out 'Future Blot8¢hnologl8ts' IFutBio) an Initiative lo encourage engagement belwe8n slud8nls aged 16-21 and the UK Iwe 8oience 68ctor lo Insplre students to pursue a career In the sector. AttractlrvJ young people into the industry is urgently ne&d8d glven the growlng skills shortagg In the area due lo the burgeoning nurnber of companies In this space. ageing and comp6titSon for tslent from olhor Induslrfes. In order lo dellver on its mls8lon, Fut810 ig contlnulng lo l)ulld up a database of Ilfe 8cl8nce companies In the UK. The database now includes 21,992 comp8nles and 74,326 offir[s. In additlon, it is collecting a list of schools and higher educatlon organisations in diffent parts of the UK. This database18 Used to Gonnecl students wllh drfferent companies in thelr area through semlnars, networklng evenl8, onllne and In peTr¢)n silé vlsits, class visits by s¢l8ntlsts, mentoring and inlemships. Following its Ilr81 event at Whe8118y Park School. Holton. Oxfordshlre on 25th Wil 2024, Fu18io held three further highly 8ucces5ful trlal events in Pinner Cambridge and L6ytonslone. The feedback from both volunteers and students was oveThvh8lmingly positive from these events wllh one of the students who attended the Leyton$tone event commentlng 'lt was 8 phenomenal 8xperi6nGe a8 I was able lo find my dream job., See Linkedln {htl s'.Ilwww.linkedin.corTII ulselsluden k-cambrid event-november-202¢2k uell and reel on Instagram (htl s-,Ilwww,insta r8m.comlmedia.fulurebiolechnolo islslreellDC9H TA feedback from the students who atterKled these events. for Future Biolechnologists is now seeking fundlng to 8UPPOrt the launch of multi-yèar evidence-led programmes for schools. The first one will focus on schools In areas of deprivallon in London (Camden, Hackney. Lambelh, Lewisham, Islington, Newham. Paddington, Southwafk and Tower Hamlets). It will be a three-year programme deliverèd In partnershlp with lo¢al unlvers4ties. research in8liiu188, medical schools and life science companies.
Infectlous disoase: What It mean8 for p•oplo Ilvlng wlth Immunosuppm*lon Slnce March 2023 the charty has been collaboratlng with researchers at the Universty of Cambridge to understand the spedflc challenges and needs Immunosuppressed patlents and their familiés face in relation to infectious disease (COV119, drug resistant infections) so that these issues cgn be addressed In better preventlon and treatment. As part of this project an onllne survey has b88n conducted with thr86 dlfferent groups.. Volunteers from the NIHR BioResourc8 Centre in Cambridge. Gambian community in Petertrxfough and Facebook support group for people wth Myo$itis, Demiatomyoslll¥, IBM and Antlsynthetase Syndrome. A number of public engagement 8Ctivities have also been carrlad out to Increase public awareness of the diffiCuleS people wlth weakened immunity experience with COVID- 19. including 8 video which can be viewed al hll s.'Ilwhalisbiolechnolo .or ind8x. h booslerlback round. PUBLIC BENEFIT The Trustees confirm that In their opinion. the work of the charlty Is of public benefit in providing a free educational resource. Th8 Trustees are all volunte8r5 who recelved no bènefit from the Charity. RI8KAS8ESSMENT The rlsk reglstsr IG regularly revlewed and updaled by the Trustees. The key rlsks Idenllfied are secudng fundlng for the future deveiopmenl of the webslte ar#J malnlalnlng the Trust's reputatlon wlth stakeholders and fundlng agency credlblllty and malntaining the right balanc8 of skills, exporience and experbse on the Board so that the Charity Is managed wmpetentty and complles wlth regulatory reqr8rnents. FINANfAAL REVIE¥V The lolal Inc#)me lor the year was £10.005 {2024.' £10,023) wth expendlture of £16,33112024.' £21.3441. work continued wllh 9rants e1Ved in prevlous years arKI was undertaken and planned for grants e1ved in 2024-25. Expenditure related principally to these projects. the Future 8iotechnologlsts work and to building on the contént ol the webslte and malntalnlng Its securlty. The rt unre8trlcled defldt was £6,328 {2024 deflclt: £11,321) wSth unrestrbcted resep4e8 at tha erKI of tho year of £22,98412024.' £29,310). Reserves allow for the ongolng maintenance and editlrvJ of the w8bsFte. work on 8Ctivltbès to énhance the offering Dn th8 webslte and lo dovelop further offerlngs. R•vrv•8 Pollcy The Iru81ees are 8eeklng to develop re8erves that wlll o)ver the cost of three years of website maintenance to ensure Ihal the Yb$ite can be kept adve during periods when dev8lopment grants are rt avallabl8. Thts IB estimated to be £10,000. Thi8 has currently been achleved. Responslbllltles of tho Board of Tru8teo8 The Twstees are responsible for preparing the Trustees, Report and the financial statements in accordance wllh appllcable law and Unit8d Kingdom Accounting StarKlard8 (United Klngdom Generally Accepted A¢UntIng Practlce). Charity law requlres the Trustees to prepare financial statements for 8ach financial yeer. In preparing financial ststements. the Trustees are required lo.. select suitable accounting policies and then apply them consistently;
• observe the methods and principles in the Charit$ SORP., • make judgements and estimates that are reasonable and prudent-. state whether applicable UK Accounting Standards have been followad, sublecl lo any rnaterial departures discbsed and explained in the financial statements; Prepare the IlnancL81 statements on the golng concem basls unless It inapproprlats to presume that the company wlll ntInue in buslness. The Trustees 8re responsible for keeping proper accounting records which dl$close with reasonable accuracy at any time the financlal posllion of the Charlty- They are also responslble for safeguardlng ihe assets of the CharNy and hence for taklng reasonable steps for the preventton and dete¢lion of fraud and olher Irregularltle8. Signed: 12fii /I¢15 Dats: Chalr, on behalf of th8 Board of Trtea8
CHARITY COMMISSION FOR ENGLAND ANO WALES 1. Independent examinerfs report on the accounts ionA Independent Examlnerfs Report Report to th• tru5t•95 Biotechnology and Medicine Education Trust On ac(ounts for the year ended 31° March 2025 Charlty no 1165469 Set out on pages 8-11 I report to the trustees on my examlnation of the accounts of the above charfty 1.the Trust"> for the year ended 31 March ZOZS. Responslbllltles •nd basls As the charbty's trustees, you are responsible for the preparatlon of the of report 4ccount5 in accordance wlth the requirements of the Charlties Act 2011 {"the Act"). I report In respect of my examlnailon of the Trust's account5 carried out under section 145 of the 2011 Act and In carrySng out my exomlnatlon, I have followed all the appllcable Dlrectlons given by the Charity Commisslon Urer section 1451511bl of the Act. I have completed my examlnatlon. I conf4rm that no material matters have come lo my attentlon In connection wlth the examlnatlon which 81ves me cause to belleve that in, any materlal respect- • the accounting rett*rtls were not kept In accordantè with sectlon 130 of the Charftle5 Act; or the accounts dld not accord wlth the accountlng records; or the accounts dld not comply with the appllcable requirements concernin8 the forrn and content of account5 set out in the Charlties (Accounts and Reports) RegulatSons 21M)8 other than any requirement that the account5 Eive a'true and fair, view which 15 ot a matter consbdered as part of an Independent examination. I have no conrn$ and have come across no other matters in connection with the examSnatlon to whlch attention should be drnwn Trn this report In order to enable a Proper understandlng of the accounts to be reached. l. Independent •x•mSnerfs statement Pleose delete the words In the bmckets ilthey do not opply.
Sl8nod: Date: Name: Phllip Clark Relent profes51on•l qualllTotlonls} oi body FC4- Fellow of the Institute of Chartered AccountsTrts in England & Wales Addrnss: 10 Linden Fields Tunbridge Walls Kent TN2 5QN rtion B Dlsclosure Only complete If the examiner needs to highlight material matters of conrn {see CC32, Independent 8xaminalion of charity accounts: directlon8 and guldanee for examlners). ¥e here brlef d•talls of IV Items that the amlner wlshesto Idos•.
Charity Numb•r 1165469 Blotochnology and M•dieln• Educatlon Trust Stat•m•nt of Finan¢l•l Adlvitie• for tho year ondlng 311¢ Mareh 2025 202&25 202&24 Subs¢riptk)n$ and (h)natlonB 23 Incomlng r•sourcu from g•n•rat•d fund• Incomlng resources from ¢hadtable a¢1¢10$ 10,000 10,000 Total Incomlng r••our¢ 10,005 10,023 Exp•ndltur• on: Raislng funds Charltable Actfvltlos Govem8nce Costs 16.031 300 21.044 Totsl R•8ourc•a •xp•nd•d 16,331 21,344 N•t Incomlnql(oirtgolng) resources (8,326) (11,321} Trgn8fer8 betsveen funds N•t mov•m•nt In funds (6,326) (11,321 Fund8 brought fop•vard 29,310 40,631 Funds carried forward 22,984 29.310 Th8 8tatement of financial 8dlvSties Includes all galns and tosses recognlsed In the year. All Incom8 8nd 8xpenditure derlves from contlnulng actlvltlos.
Charlty Numb•r 1165469 Blotschnology and Medlclne Education Trust Balanco Shwt Is at 31* March 2025 Note 2025 2024 Curr•nt A8••t• Cash 23.882 33,176 Total Curr•nt A•••ts 23,882 33.176 Amount• falllng du• wlthln ono y•ar Cr•dltors 897 3,806 N•t ••s•ts 22.984 29.310 R•pr•8•nt•d by Total unrestrlcted funds 22,9B4 29,310 Chair of Trusl••s Approved by the truslees on
Charity Number 1165469 Blot•chnology and Modiclne Educatlon Trust Notes to thg Financlal Statémènts for tho yur 0nding 311t March 2025 Noto 1: Ac¢¢)untlng Pollcle8 a) Basis of Preparallon These financial 8tstements have been prepared under the hlstorlcal cosl convention and in accordance with th8 Statement of R8MMended Pralce., Accounting and Rgporting by Charities and the financial framework applicable in the UK (FRS102) and the charle8 Ad 2006. The charfty meets the definltlon of a publlc benefft entlty under FRS102. These accountlng pollcles have been appllod o)nsistonty throughout the rrent and previous perlods. b) Slocks StoGk8 8re ststed al, the lower of cost and net r8811sable value. No 8tock was recorded during the year 88 8ny resourc86 expended on $aleabl8 iiems were mlnlmal and charged to expenditure. c) Funds Restrtcted funds are glven to the Trust for speofic purposes and are expendable by the TN8tee8 In furtherance of partl¢ular prole¢ts. Unreslri¢led funds are 8V8llabb for any purpose of the Trust. Thore were rK* resfficted funds during the year. dl Incoming resources Incoming resources are recognised once the Trust has entitlement to the resourc88. it is certain Ih8t the resources will b6 received and the monetary value of Incomlng r860urces can be measurnd with sUffiCnI reliability. e) Resource8 experKled All exp8ndlture18 accounted for on an ac¢ru818 ba818 and h88 boon cla88rfied under he8dlngs that 8ggr•gate all coats related to the c818gory. All expendllure18 rncogni8ed once Ih8r818 leg81 or constructlve obligation committlng the Tfust to thé expendltura. n Cost of generating funds The &)sls ol generatlng fvnds are those costs attribulable to generatlng IrKomlng r080urces for Ihe Trust, other than those costs Incurred In undertaking charltable activities. 9> Charit8bla a¢tiviti85 Costs of Charitable activities Gomprfse all costs incurred in Ihe pursuit of the charltable objectlves of the Trust. io
Charlty Numb•r 110U Blotschnology and Medlclno Educallon Trust Notss to th• Flnancial Stat•m•nts for th• y•ar endlng 31•t March 2025 2023 2023-24 Not• 2: Sub•¢rlptl¢)n• and donations Donations 23 Chafltsble actlvlll8s- grants 10,000 10,000 10,OOS 10,023 Not• 3: Exp•ndltur• R8lslng fund6 Charltable actlvrt188 18,031 21,044 300 Govemance costs 300 16,331 Charilable 8ctivltie8 Includes all oosts relating to th6 producllon of rJ)ntent, malntsnance arKI developrMnt of the websii8 and to putting on events. 21,344 Not• 4.. Cr•dltor8 2025 2024 Trade Cr8dEtor8 897 897 3.806 Thore were no r61aled party transactions during the year. li