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Trustees’ Annual Report For the period: 01 July 2024 to 30 June 2025

Reference and Administration Details

Charity: Foundation for Prader-Willi Research UK (FPWR UK) Registered Charity Number: 1141923 Address:

5 St Peters Close Bishop Auckland County Durham DL14 6DD

Trustees:

Catherine Shaw – Chairperson
Danica Matheson – Treasurer
David Jack – Secretary
Angela Saunders – Trustee
Evelyn Close – Trustee

Structure, Governance and Management

Governing Document: Trust Deed Charity Constitution: Trust

Trustee Appointment: Trustees are appointed by existing trustees.

Objectives and Activities

The objectives of FPWR UK are to advance the education of the public in general (and particularly amongst scientists) on the subject of Prader-Willi Syndrome and to promote research for the public benefit in all aspects of that subject and to publish the useful results.

Funds have been generated through the following initiatives:

Community Fundraising Events:
Bonus Balls, One Small Step Portsmouth, London Marathon, Manchester Marathon, 100 miles in May, MX Reality Raffle, Fashion Show, Dog walking for Research, Wheelie Race, Virtual Balloon Race, Auction 2024, Boiler Servicing Donations, 10 mile swim, Christmas Raffle, East London Synagogue and Petts Wood Bowl Charity of

the Year partnerships, Wild West Fundraiser, Art Classes & Exhibition, Ceilidh, Quiz Night, Kiltwalk Glasgow, One Small Step Stockport, and 2nd virtual screening of The Life We’re Given.

Collaborative Efforts:
Move It May with PWSA UK (including merchandise sales in May)
Online and Ongoing Support:
easyfundraising.org
Givestar
Stripe
Justgiving
DONR
Charities trusts

All events were organised to raise funds and awareness to support PWS research. Trustees carefully considered the Charity Commission’s guidance on public benefit while setting objectives and planning activities.

Achievements and Performance

During the financial year 2024-2025, FPWR UK contributed £48,986.31 towards the below research project :

Dr. Herve Mione (Institute of Genetics and Molecular and Cellular Biology) – $64,800 ( £48,986.31) contributed towards research on Assessing DGKK Dysregulation in PraderWilli Syndrome . Fully funded.

Financial Review

FPWR UK maintains a minimum reserve of £5,000 to cover approximately three months of essential operating costs , including staff wages and storage facility expenses. This reserve ensures the charity can continue to function effectively in the event of unexpected income shortfalls or delays. The reserve requirement is reviewed annually to reflect the charity’s financial commitments and operational needs.

FPWR UK confirms that no funds are in material deficit.

Declaration

The trustees declare that they have approved the annual report outlined above.

Signed on behalf of the charity’s trustees:

Catherine Shaw

Chairperson Date: 12th April 2026

FOUNDATION FOR

PRADER-WILLI REASERCH

UNITED KINGDOM

ACCOUNTS FOR THE YEAR TO 30 JUNE 2025

Registered Charity 1141923

FOUNDATION FOR PRADER-WILLI RESEARCH UNITED KINGDOM CONTENTS ACCOUNTS FOR THE YEAR TO 30 JUNE 2025

Independent Examiners Report	1
Income & Expenditure	2
Balance Sheet	2
Notes to the Accounts	3
Declaration	4
ANNEX
Annual Report

FOUNDATION FOR PRADER-WILLI RESEARCH UNITED KINGDOM INDEPENDENT REPORT TO THE TRUSTEES ACCOUNTS FOR THE YEAR TO 30 JUNE 2025

I have been requested to report on the accounts of the Charity for the year ended 30 June 2025.

Respective responsibilities of Trustees and Examiner

As the Charities trustees you are responsible for the preparation of the accounts: you consider that the audit requirements of section 43(2) of the Charities Act 1993 (the ACT) does not apply. It is my responsibility to state, on the basis of procedures specified in the General Directions given by the Charity Commissioners under section 43(7)9b) of the Act, whether particular matters have come to my attention.

Basis of Independent Examiners Report

My examination was carried out in accordance with the General Directions given by the Charity Commissioners. An examination includes a review of the accounting records kept by the Charity and a comparison of the accounts presented with those records. It also includes consideration of any unusual items or disclosures in the accounts, and seeking explanations from you as trustees concerning any such matters. The procedures undertaken do not provide all evidence that would be required in an audit, and consequently I do not express an audit opinion on the view given by the accounts

Independent Examiners Statement

In connection with my examination, no matter has come to my attention:

1 which gives me reasonable cause to believe that in any material respect the requirements:-

to keep accounting records in accordance with section 41 of the Act: and

to prepare accounts which accord with the accounting records and to comply with the accounting requirements of the Act

have not been met: or

2 to which in my opinion, should be drawn in order to enable a proper understanding of the accounts reached.

LYNDA ELIZABETH LEBETER Date 18 April 2026

Independent Examiner

Willow House 20 Ryburn Close Canterbury Gardens Moorgate Park Clifton York YO30 4XH

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