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2022-03-31-accounts

ANNUAL
REPORT CONTENTS
TRUSTEES' REPORT INCORPORATING THE STRATEGIC REVIEW
STRATEGIC REVIEW.
FINANCIAL
REVIEW .
RISKASSESSMENT AND MANAGEMENT.
STRUCTURE, GOVERNANCE
AND		 MANAGEMENT. 10
STATEMENT OF TRUSTEES' RESPONSIBILITIES .14
INDEPENDENT AUDITOR'S REPORT .15
FINANCIAL STATEMENTS .18
REFERENCE AND ADMINISTRATIVE
DETAILS		 34

-
~ ~ ~
~
Continue the growth During the last financial
year scientists
at El published
119publications
and shared 24
and development of technical
products
(webtool/application/software)
with
the wider scientific
community.
our world leading Our
scientists
also
delivered
23 oral
presentations
at
national
and
international
investigator-led conferences.
The diversity
of our funding
portfolio has expanded
with funding
received
research program, from Wellcome,
MRC and NERC in addition
to BBSRC.
continue to publish
high quality scientific
outputs, and diversify
our income streams.
Build strong
industrial
collaborations
so
that we are aligned		 El's expertise
in bioinformatics
and genomics
is one of the seven technology
families
recognised
with the Government
strategy.
El has demonstrated
its impact via its public
affairs
works,
both
during
the COVID pandemic
as well as by engaging
with those
involved
in drafting
the proposed
gene editing legislation.
to the We managed
15projects with 17 industrial
partners
funded
by: UKRI (BBSRC,EPSRC,
Government's Innovate
UK, MRC), Home
Office, Royal Academy
of Engineering,
University
of East
strategy and so we
can achieve impact
from our research		 Anglia,
and
industry.
Our collaborations
span
plant breeding
and agrochemical
sector,
biotech
industry,
specialist
sequencing
and
instrumentation
companies,
data
management
and bioinformatics
companies,
and defence and security sector. We have
maintained
existing, and developed
new, relationships
with industry
through
mechanisms
such
as external
engagement
events,
industry
seminar
programme
and
joint
PhD
studentships.
Our industry
facing event El Innovate
2021 attracted 211 attendees
from
85 different organisations,
among those 173external
participants
and generated
16new
connections
with
industry
and academia,
leading
to 6 new collaborations
with
industry.
The event showcased
collaborations
across 3 institutes
on the Norwich
Research Park:
Earlham
Institute,
John Innes Centre, and Quadram
Institute.
Projects
to
translate
our
research
and
help
to
realise
societal,
economic
and
environmental
impact,
nationally
and
internationally
included:
Identification
of novel
SARS-Cov-2 lineages
from
mixed wastewater
samples;
Quantifying
the transmission
routes ofgastroenteritis
in Pakistan
and developing
targeted
interventions;
Development
ofa modular
synthetic
biology pipeline for the engineering
bioactive dyes which can help
to reduce environmental
impact of the textile dyeing
industry;
Investigating
a new drug
target for treatment
of schizophrenia
with the international
Psychiatry
Consortium,
a E4
million
collaboration
between
seven
global pharmaceutical
companies
and two leading
research charities; and delivering
standards
for data-driven
bioscience.
We conducted
the assessment
of socio-economic
impact of the Earlham
Institute
for
2019-2021 which
resulted
in a forecast
contribution
of circa F4 billion
to the global
economy over the next 10years, with return
on investment
614for every F1 invested.
Strengthen our Work continues
through
our collaboration
with
WorldFish
which
aims
to accelerate
partnerships through selective breeding oftilapia
in the Lake Victoria Basin catchment
working
with institutions
collaboration with based
in Kenya, Tanzania
and Uganda.
From 2021 El is a partner
in the WorldFish
world leading CGIAR
Research
Programme,
delivering
high
quality
genomic
resources
and
institutes and contributing
to the characterisation
ofthe genomic bases ofaquaculture
traits. WorldFish
scientists that align is proposed as a core partner
in the new Institute strategic programme
grant,
iffunded to
with our scientific commence
from April 2023. The UKRI GCRF GastroPak
project continues
(2021- end
strategy. 2023) through
which
El is leading
a partnership
with
institutes
in Pakistan
(National
University
of Sciences
& Technology
in Islamabad
and
the
University
of Agriculture
Faisalabad),
the
National
University
of Galway
and
other
UK
institutes.
This
a
multidisciplinary
project to quantify
the transmission
routes ofgastroenteritis
in Pakistan
and develop targeted
interventions.

'.
~ ~ ~
~
Continue to We have used our website
and social media to run campaigns
to highlight
our new
communicate our vision, mission and strategy which were well received
by our stakeholders.
Alongside
science through our this, we have had a focus on communicating
our impact,
particularly
with pieces on
public engagement aquaculture
and
wheat
that demonstrate
our contribution
in these
key areas
of
program to a wide research.
audience,
promoting		 the We attended
the
Royal Society Summer
Showcase,
a virtual
event
that saw us
importance
of		 publicly produce
a short
documentary
on the
plight
of pollinators
and
an
online
game
funded research to the showcasing
our research
on bees. Feedback was extremely
positive and led to the
general public. Royal Society asking
us to feature the Bee Trail at the European
Science Festival,
organised
by the Slovenian
Science Foundation.
Our Barcoding the Broads outreach
work trained over 100people
in DNA barcoding,
reaching
teachers,
technicians,
students,
naturalists
and
local
artists.
We also
received funding
for ajoint project with Kew Gardens and a local nature group to look
at fungi. We also secured an invitation
to exhibit the Darwin Tree of Life project at the
2022 Royal Society Summer Science Exhibition
with Wellcome Sanger Institute.
We also started a project to rebuild our website, with a launch
in early 2022/23 to help
us ensure
it is fitfor the future, remains secure, meets accessibility
requirements,
and
gives visitors the best possible user experience.

~
~
~
~I 0
~
~ ~ ~ ~
& El
is
unable		 to keep pace with & Bidding
into Capital
Grant		 opportunities
to
developments in technology underpinning refresh
platforms.
its science. &Technology
strategy
kept		 under regular
& Funding
and/or		 cost recoveries are review and funding
opportunities		 identified
inadequate
to
sustain
and
technology
facilities
necessary
to
scientific objectives.		 improve
support		 and pursued
for technology
investments.
& El has
reserves
that
enable
it to move
quickly
when
technology
enhancements
become available.
& El is not able to access EU programme & Regular dialogue
with
UKRI - BBSRCand
funding
or		 participate in EU research other
key
stakeholders		 on
risks
and
collaborations. emerging
issues
with respect to		 potential
& El is not able to recruit or retain researchers changes
in arrangements.
from EU member countries. & Kept abreast of risks and potential
impact
& El
is
not
international
Government		 able
to
continue
with
its
funding
programmes
due to
Overseas
Development
Aid		 from staff leaving
El/UK,
and ensure
we
prepare
for the new immigration
and visa
process post BREXIT.
budgets cuts. & Realign
overseas
programmes		 into
new
and evolving
funding
programmes		 as they
arise.
~ ~
~ ~ ~ ~ ~
~ ~ ~ ~ ~
~ ~ & El
fails
to		 comply with sponsor grant & El is subject to regular
reviews of its grant
~ ~ ~ ~ ~ requirements resulting in a material compliance
processes
from sponsors
and
financial
impact.		 the
Research
Councils		 UK internal
auditors.
~ ~ ~
~ ~ ~ ~
~ ~ ~
~ ~ & Risking energy prices mean that current & El to keep funders abreast of rising energy
funding levels, and business plan are costs, and look for funding opportunities to
unsustainable long term. assist
with
rising costs of		 delivering
core
programmes.
& El to increase energy usage monitoring
and
reporting
to enable
it to review
its energy
consumption
and operational
practices		 to
ensure best energy efficiency.
& El to continue
to buy energy
at the best
price via working
with others on the NRP		 to
secure future energy prices at best value.

At date ofReport:
Professor Peter Holland (Chair) Rem Com
Dr Alasdair Macnab AC (Chair), Rem Com (Chair)
Professor Thomas Richards
Ms Amanda
Tagg		 AC, Rem Com
Professor Edward
Louis		 AC (up to 12October 2021)
Professor Philip Gilmartin AC (from 12October 2021)
Professor Deborah
Smith		 Rem Com (from 7 December 2021) Appointed 7 December 2021
Dr Lars Magnus
Rattray		 Appointed 21 June 2022
Dr Stephanie Joan Pilkington Appointed 21 June 2022
During the year:
Professor Dame Janet Thornton (Chair) Resigned 29 March 2022
Mrs Andrea Finegan AC, Rem Com (Chair) Resigned 21 June 2022
Professor Jean Beggs Rem Com Resigned 7 December 2021

Unrestricted Restricted Restricted Total Total
funds funds capital 2022 2021
Note f000 f000 f000 f000 f000
Income
Income from charitable activities
Grant Income - BBSRC 8,668 8,668 8,466
Grant Income - other 1,580 1,580 566
Other Research Income 860 860 386
Capital funding
—BBSRC		 126 2,535 2,661 1,192
Income from other trading activities
Trading
income		 293 293 409
Rental income 26 26 26
Investment
income		 10 47 47 56
Other generated income 126 126 43
Total income 2 1,352 10,374 2,535 14,261 11,144
Expenditure
Charitable
activities		 3 (1,056) (9,673) (2,459) (13,188) (12,307)
Raising funds (115) - - (115) (122)
Trading expenditure (103) (103) (83)
Total ex
nditure		 1,274 9,673 2,459 13,406 12,512
Net incomel ex enditure for the ear 78 701 76 855 1,368
Other transfers 20 (359) 359
Capital transfers 20 901 (400) (501)
Net movement
in funds		 620 660 425 855 1,368
Funds brought forward 11,786 1,289 8,546 21,621 22,989
Funds carried forward 20 12,406 1,949 8,121 22 476 21,621

Group Group Company Company
2022 2021 2022 2021
Note OOOO OOOO 6000 f000
Fixed assets
Tangible assets 11 9,211 9,350 9,211 9,350
Intangible
assets		 12
Current assets
Stocks 14 222 163 222 163
Debtors 15 4,722 3,164 4,578 3,005
Cash at bank and in hand 16 14,667 15,461 14,606 15,329
19,611 18,788 19,406 18,497
Current
liabilities
Creditors:
amounts		 falling due within one year 17 (6,346) (6,517) (6,333) (6,483)
Total net current assets 13265 12,271 13073 12,014
Total assets less current liabilities 22,476 21,621 22,284 21,364
Total net assets 19 22 476 21,621 22 284 21,364
The funds ofthe charity
Restricted funds
Fixed asset reserve 20 8,121 8,546 8,121 8,556
Designated
reserves		 20 1,625 861 1,625 861
General reserve 20 324 428 324 428
Total restricted
funds		 10,070 9,835 10,070 9,845
Unrestricted
funds
Fixed asset resene 20 1,090 804 1,090 804
Designated
reserves		 20 7,382 6,877 7,382 6,877
General resene 20 3,934 4,105 3,742 3,838
Total unrestricted funds 12,406 11,786 12,214 11,519
Total funds 22 476 21,621 22 284 21,364

Total Total
2022 2021
Note OOOO OOOO
Cash flows from operating activities:
Operating
profit/(deficit)		 855 (1,368)
Interest receivable (47) (56)
Depreciation
and amortisation		 2,459 3,064
Capital grants received (2,661) (1,192)
Loss on disposal of tangible assets 20 169
Increase
in stocks		 (59) (83)
Increase
in debtors		 (1,558) (1,087)
(Decrease)/Increase
in creditors		 (171) 1,549
Net cash (used in) I provided by operating activities (1,162) 996
Cash Flows from investing
activities:
Interest received 47 56
Purchase
of tangible assets		 (2,349) (1,728)
Capital grants received 2,661 1,192
Proceeds from sale of tangible assets 9
Net cash provided
by I (used		 in) investing activities 368 (480)
Change
in cash and cash		 equivalents in the reporting period (794) 516
Cash and cash equivalents at the beginning of the period 16 15,461 14,945
Total cash and cash equivalents at the end ofthe year 16 14,667 15,461

2.
ANALYS		 IS OF INCOMING RES OURCES
Research Other Total Research Other Total
activities activities 2022 activities activities 2021
L'000 L'000 6000 f000 f000 6000
Grant income
BBSRC 8,668 8,668 8,466 8,466
Other government departments 546 546 72 72
European
Union		 7 7 24 24
Universities 618 618 246 246
Other charities 744 744 396 396
Other grants 525 525 214 214
Total
rant income		 11,108 11108 9,418 9,418
Capital grants
BBSRC
Capital expenditure 2,661 2,661 1,192 1,192
Total ca ital
rants		 2,661 2 661 1,192 1,192
Trading
income
Earlham
Enterprises		 Ltd 293 293 409 409
Rental income 26 26 26 26
Total tradin
income		 319 319 435 435
Investment
income
Interest receivable on cash deposits 47 47 56 56
Total investment income 47 47 56 56
Other income
Other income 126 126 43 43
Total other income 126 126 43 43
Total incomin
resources		 13,769 492 14261 10,610 534 11,144

Expenditure on charitable activities and governance
costs have be		 en analysed
below.
Total Total
Ex enditure on charitable activities 2022 2021
Note f000 f000
Direct charitable expenditure:
Staff costs 4,587 4,501
Direct costs 4,680 3,291
Depreciation 2,459 3,064
Governance costs 104 95
Support costs 4 1,358 1,356
Total ex enditure 13188 12,307
Total Total
Ana
sis of		 overnance costs 2022 2021
f000 f000
Staff costs 99 93
Other costs 5 2
Total
overnance costs		 104 95

(depreciation)
off2,459k (2021:E3,064k).
4.
ALLOCATION
OF SUPPORT		 All other expenditure
COSTS		 is unrestrict ed.
Charitable Raising Total Charitable Raising Total Basis of
Activities Funds 2022 Activities Funds 2021 Allocation
FOOO 6000 f000 6000 6000 6000
Building services* 477 477 507 507 Activity
Finance and Contracts* 190 115 305 196 122 318 Activity
Management,
ITand Communications*		 349 349 328 328 Activity
Human
Resources and Staff Welfare*		 138 138 127 127 Activity
Other support services 21 68 89 19 57 76 Activity
Total support costs 1,175 183 1,358 1,177 179 1,356

Operating
surplus
is state		 d after c harging :
Total Total
2022 2021
f000 f000
Audit services:
Fees for the audit of the charitable company and consolidated financial statements 12 12
Fees for the audit of the charitable company's subsidiary pursuant to legislation 2 2
Non-audit
services:
Other fees payable to the auditors
of the charitable		 company
Depreciation 2,459 3,064
Loss on disposal of tangible assets 20 169
Operating
lease rentals
(land		 and buildings) 130 101
Hire of plant and equipment 9 4
Loss on foreign exchange translations 7 10
7.
RESULTS OF TRADING ACTIVITIES		 OF SUBSIDIARY
Total Total
Earlham
Enterprises
Limited		 2022
f000		 2021
f000
Profit and loss account
Turnover 293 409
Cost ofsales (103) (153)
Gross profit 190 256
Administrative
e
enses
Operating
profit retained		 in subsidiary 190 255
Net assets at 31 March 2022 192 257
In addition
to the above, f254,745(2021:f135,503)		 in Gift Aid was paid to the charitable company in the year.
8.
REMUNERATION		 OF MEMBERS OF THE BOARD OF TRUSTEES
El has been given
approval		 by the Charities Commission to remunerate trustees where the Board considers
that		 payment
is
necessary to attract trustees with specialist skills and experience. The power to remunerate
trustees		 is included in El's Articles
ofAssociation.
Seven members
of the Board of Trustees		 received remuneration from the group during the year for their duties as a Trustee
(2021:six). Total trustee remuneration in the year was f28,000 (2021:f29,000). Details ofthe remuneration
paid		 during
the
year is as follows:
Total Total
Name ofTrustee 2022 2021
f000 f000
Professor Peter Holland
Professor Thomas Richards
Professor Dame Janet Thornton
Mrs Andrea
Finegan
Dr Alasdair
Macnab
Professor
Edward
Louis
Professor Deborah Smith
Professor
Phili
Gilmartin
Total 32 29

The average monthly number of persons employed number of persons employed number of persons employed by or deployed by or deployed to the group, analysed to the group, analysed by category, was as follows:
Grou
and		 charitable com an 2022 2021
Number Number
Scientific 99 91
Office mana ement and services 18 17
Total 117 108
The aggregate
payroll		 costs ofthese persons were:
2022 2021
Note f000 OOOO
Wages and salaries 4,278 4,117
Redundancy costs 4 5
Social security costs 423 433
Other pension costs 22 644 602
Total 5,349 5,157
As required by Charites SORP an analysis has been provided below of the number of staff who fall within emoluments bands
from f60,000 upwards.
Grou
and		 charitable com an 2022 2021
Number Number
260,000 —F69,999
F70,000 - F79,999
280,000 —F89,999
2100,000 - F109,999
2110,000 - F119,999
2160,000 —F169,999
Total 12

Total Total
2022 2021
OOOO f000
Bank interest 45
Interest on loans 2
Total 47 56

11.TANGIBLE A SSET S
Plant,
machinery Assets
Leasehold and under
Grou
and charitable		 corn an im rovements e ui
ment		 construction Total
f000 f000 OOOO OOOO
Cost
At 1 April 2021 8,661 27,191 1,042 36,894
Transfers 549 469 (1,018)
Additions 814 1,052 483 2,349
Dis osals 2,394 24 2,418
At 31 March 2022 10 024 26318 483 36825
Accumulated
Depreciation
At 1 April 2021 5,697 21,847 27,544
Charge for the year 256 2,203 2,459
Dis osals 2,389 2,389
At 31 March 2022 5 953 21 661 27 614
Net book value at 31 March 2022 4 071 4657 483 9211
Net book value at 31 March 2021 2,964 5,344 1,042 9,350
All ofthe charitable company assets at 31 March 2022 are used for direct charitable purposes.

12. INTANGIBLE ASSETS
Software
Grou develo ment Total
f000 OOOO
Cost
At 1 April 2021 177 177
Additions
At 31 March 2022 177 177
Accumulated
Depreciation
At 1 April 2021 177 177
Char efor the
ear
At 31 March 2022 177 177
Net book value at 31 March 2022
Net book value at 31 March 2021

undertaki ng
in whi		 ch the charitable company
has an interest:
Country of Class and percentage of
Subsidia Undertakin re istration Princi al activit shares held
Earlham Enterprises Limited England Contract research 100%ordinary shares

Total Total
Grou and charitable corn an 2022 2021
f000 OOOO
Raw materials and consumables 222 163
Total 222 163

Group Group Company Company
2022 2021 2022 2021
Note OOOO OOOO OOOO OOOO
Grants receivable:
from government bodies 1,651 407 1,651 407
from other sources 875 243 875 243
Trade debtors 458 314 334 70
Amounts
owed by		 subsidiary undertakings 20 85
Amounts
owed by		 other related parties 23 247 171 247 171
Other debtors 297 73 297 73
Pre a ments and accrued income 1 194 1,956 1 154 1,956
Total amounts
fallin		 due within one ear 4722 3,164 4578 3,005
The above amounts
fall		 due within one year.
Grants receivable from government bodies includes F427,730 in relation to capital funding receivable from BBSRC (2021:
F75,602).
16.
CASH		 AT BANK AND IN HAND
Group Group Company Company
2022 2021 2022 2021
OOOO FOOO OOOO FOOO
Cash at bank 14667 15,461 14606 15,329
Total 14,667 15,461 14,606 15,329
17.
CREDITORS: AMOUNTS		 FALLING DUE WITHIN ONE YEAR
Group Group Company Company
2022 2021 2022 2021
Note OOOO FOOO OOOO FOOO
Grants received in advance:
from government bodies 695 1,049 695 1,049
from other sources 475 387 475 376
Amounts
owed to		 other related parties 23 214 307 214 307
Trade creditors 1,271 1,216 1,271 1,216
Other creditors 1,666 962 1,653 939
Taxation and social security 105 106 105 106
Accruals and deferred income 1 920 2,490 1 920 2,490
Total amounts
fallin		 due within one ear 6346 6,517 6333 6,483
18.
RECONCILIATION		 OF MOVEMENT IN GRANTS RECEIVABLE
Total Total
Group 2022 2021
Note F000 f000
Grants receivable 15 2,526 650
Grants received
in advance		 17 (1,170) (1,436)
Net grants receivable at the end of the year i(received in advance) 1,356 (786)
Net grants received
in		 advance at beginning of year (786) (884)
Grant monies received during the year (8,106) (8,934)
Grant money released to SOFA during the year 10,248 9,032
Net grants receivable at the end of the year I (received in advance) 1,356 (786)

19.
ANALYSIS OF NET ASSETS BETWE		 EN FUNDS
Net
Fixed current Total
assets assets 2022
f000 f000 OOOO
Group
Unrestricted:
Fixed asset reserve 1,090 1,090
Designated
reserves		 7,382 7,382
General reserve 3,934 3,934
Restricted:
Fixed asset reserve 8,121 8,121
Designated
reserves		 1,625 1,625
General reserve 324 324
Total net assets 9211 13265 22,476
Charitable
company
Unrestricted:
Fixed asset reserve 1,090 1,090
Designated
reserves		 7,382 7,382
General reserve 3,742 3,742
Restricted:
Fixed asset reserve 8,121 8,121
Designated
reserves		 1,625 1,625
General reserve 324 324
Total net assets 9211 13073 22,284
Net
Fixed current Total
assets assets 2021
f000 FOOO f000
Group
Unrestricted:
Fixed asset reserve 804 804
Designated
reserves		 6,877 6,877
General reserve 4,105 4,105
Restricted:
Fixed asset reserve 8,546 8,546
Designated
reserves		 861 861
General reserve 428 428
Total net assets 9350 12271 21 621
Charitable
company
Unrestricted:
Fixed asset reserve 804 804
Designated
reserves		 6,877 6,877
General reserve 3,838 3,838
Restricted:
Fixed asset reserve 8,546 10 8,556
Designated
reserves		 861 861
General reserve 428 428
Total net assets 9350 12014 21 364

Unrestricted Restricted
fixed Unrestricted Unrestricted Restricted fixed Restricted Total
reserve desi nated eneral desi nated reserve eneral 2022
OOOO f000 f000 f000 OOOO f000 f000
Group
At 1 April 2021 804 6,877 4,105 861 8,546 428 21,621
Operating
surplus
for		 the year 78 76 701 855
Capital transfers 182 29 (211)
Unrestricted
general		 capital expenditure 104 (104) (526) 400 126
Unrestricted
designated		 transfer 609 (420) 600 (789)
Restricted designated transfer 690 (690)
Other transfers 142 142
At 31 March 2022 1,090 7,382 3,934 1,625 8,121 324 22,476
Charitable
company
At 1 April 2021 804 6,877 3,838 861 8,556 428 21,364
Operating
surplus
for		 the year 143 76 701 920
Capital transfers 182 29 (211)
Unrestricted
general		 capital expenditure 104 (104) (526) 400 126
Unrestricted
designated		 transfer 609 (420) 600 (789)
Restricted designated transfer 690 (690)
Other transfers 152 10 142
At 31 March 2022 1,090 7,382 3,742 1,625 8,121 324 22 284
Unrestricted Restricted
fixed assets Unrestricted Unrestricted Restricted fixed Restricted Total
reserve desi nated eneral desi nated reserve eneral 2021
6000 f000 f000 f000 f000 f000 6000
Group
At 1 April 2020 951 5,572 4,530 1,651 9,904 381 22,989
Operating
surplus/(deficit)		 for the year 190 (2,073) 515 (1,368)
Capital transfers (252) 169 83
Unrestricted
general capital expenditure		 105 (105)
Unrestricted
designated		 transfer 773 (615) (158)
Restricted designated transfer (632) 632
Other transfers 468 468
At 31 March 2021 804 6,877 4,105 861 8,546 428 21 621
Charitable
company
At 1 April 2020 5,572 4,392 1,651 9,914 381 22,851
Operating
surplus/(deficit)		 for the year 71 - (2,073) 515 (1,487)
Capital transfers (242) 169 (10) 83
Unrestricted
general capital expenditure		 105 (105)
Unrestricted
designated		 transfer 773 (615) (158)
Restricted designated transfer (632) 632
Other transfers 468 468
At 31 March 2021 804 6,877 3,838 861 8,556 428 21 364

Total Total
Grou and charitable com an 2022 2021
OOOO f000
Capital commitments at the end of the financial year for which no provision has been made:
Contracted 992 892
Total Total
Grou and charitable corn an 2022 2021
OOOO f000
Amounts due under other operating leases for land and buildings:
Under one year 100 100
Between one and five years 400 400
Over 5
ears		 1 276 1 376
1 776 1 876
Amounts due under other operating leases for plant and machinery:
Under one year
Between one and five years
Over 5
ears