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2023-12-31-accounts

JNETICS (A Company Limited by Guarantee) DIRECTORS, REPORT AND FINANCIAL STATEMENTS FOR THE YEAR ENDED 31 DECEMBER 2023

JNETICS {A Company Limited by Guarantee) FOR THE YEAR ENDED 31 DECEMBER 2023 Pa Legal and Adminislralive details Directors, Report Independent auditor's report 8-10 Statement of Financial Activities 11 Balance Sheet 12 statement of Cash flows Notes to the Financial Statements 14-19

JNETICS {A Company Limited by Guarantee) FOR THE YEAR ENDED 31 DECEMBER 2023 Dirgctors & Tru$t90S: A L Angel AMLeon L Blitz Drmziff Emay L Birnbaum Dr J Harris N Goldschneider (resigned 21 August 20231 Registered Office.. Unil 207 Balfour House 741 High Road, Finchley. London N12 OBP Independent auditor: Goldwins Limited, Chartered Accountants 75 Maygrove Road, West Hampslead, London, NW6 2EG Bankers.. Barclays Bank UK PIC 1 Churchill Place London E14 5HP Charity registration number: 1134935 Company registration number: 07087270

JNETICS {A Company Limited by Guarantee) FOR THE YEAR ENDED 31 DECEMBER 2023 TRUSTEES I DIRECTORS. REPORT Principal Activities and Charitablg Objodivgs The charity was established for the following purposes.. To increase awareness and understanding of Jewish genetic disorders IJGDsl among affected families, patient groups, healthcare professionals, and the Jewish and wider ￿mMunity. To improve access lo the best available information, services, and support relating to Jewish genetic disorders. To facilitsle access lo responsible and professional testing services for people at risk of passing on, and those direcuy affected by, Jewish genetic disorders. In establishing the activities of the charity, the directors have given due consideration to the Charity Commission's gLJidance regarding the provision of PLJblic benefit. Achigvements and Porformanco The first half of 2023 saw the launch of the charity s second matched funding campaign, which contributed substantially to the appeallgrants income for 2023 as well as introducing over 2,500 new donors to Jnelics, helping us lo deliver on our twin objectives to ensure no further children are bom into our community with any of the devastating genetic conditions that Jnetics lesls for and lo improve the prevention and management of Jewish Genetic Disorders. In January 2023, the NHS Jewish BRCA Testing Programme was launched as a pilot, with Jnetics and Chai delivering the engagement campaign in support of the programme. The results were so successful, that a delay was imposed on the hard launch whilst additional testing procured to ensure that demand could be mel at the lime of the hard launch. Following the atrocities of October 7th a decision was made not to fundraise proactively for last quarter half of the year, as the community's focus shifted lo Israel and Israeli charities. Nevertheless, the fundraising successes enjoyed in the first three quarters of the year further secured the financial stability achieved in 2022, ensuring that we could continue lo support the needs of the community. Further highlights of 2023 included= Growth of the Jnelics in Schools Programme, to include non- Jewish schools with high numbers of Jewish students Continued growih of Jnelics on Campus, achieving ils highest ever numbers of screenings The laLJnch of a new bimonthly Scienttfic Lecture series "Diving into our Gene Pool "improving awareness within community of genetic issues and helping Jnelics fulfil its role as the community s source for infomation and support on genetics and health A Chanukah concert attended by 200+ guests al a lime when the Community needed an uplift 2023 saw growth across all 3 recessive screening programmes. The Jnelics clinic functioned at near capacity 1342 vs 318 in 20221. The Jnelics on Campus universities programme continued lo demonstrate year on year growth with 324 students screened during 20231209 in 20221. The schools programme demonstrated further recovery, and. together with educating and screening in all 8 mainstream Jewish secondary schools, we began the expansion of our school screening and education into non-Jewish schools with a large number of Jewish students, so that the schools programme grew over 50 % 1526 in 2023 vs 349 in 20221, Continuing ils recovery following the COVID pandemic. The success and growth across all 3 of our screening programmes was aided by our new expanded panel (launched Sept 20211 which has increased our relevance lo all sectors of the community,. and in the case of the clinic the inlroduelion of "couples screening. has improved take up of screening by parb'cipants thinking of having a child. The move to a virtual screening pro￿$$ for the clinic and the

JNETICS {A Company Limited by Guarantee) FOR THE YEAR ENDED 31 DECEMBER 2023 universities programme has also enabled us lo screen greater numbers across a wider geographi reach al greater convenience to participants and reduced lime and cost. Only the schools, programmes remain 'in person,, giving us an opportunity lo incorporate our educational work. Plans for Future Periods The first half of 2024 has gol off lo an encouraging start. Following the hugely successful pilot launch in January 2023, the new NHS BRCA screening programme was formally launched on 30th January 2024 at The House of Lords. The launch exceeded expectations, with a strong marketing, social media and PR presence ensLJring over 21,000 people signin9 UP to be screened by the end of May 2024, well ahead of target. The NHS Jewish BRCA Testing Programme is leading to an increased focus for Jnetics on hereditary cancers. In April 2024, following an extensive bid process, Jnelics working closely wwth Chai Cancer Care was re-appointed until June 2026 as the engagement partner for the programme. Jnelics continues lo be the community's primary initial resource for information and screening on both recessive and dominant disorders. The Young Professionals Committee continues lo grow. In early 2024, the committee ran a second young professionals supper quiz for 200 young adults. helping lo spread the word lo our largel audience. Earfy May saw the charity hold ils second ladies, event. This was a significant success both in terms of both attendees1160 vs 40 in 202211 and funds raised, and introducing a number of new fa￿S to our work al Jn81ics. This event shows sign of becoming a permanent annual fixture in the fundraising calendar. Earfy June, saw the charity hold ils second golf day. Building on the learnings of last year, a number of new participants came along and enjoyed the day. too is becoming a permanent annual fixture in the fundraising calendar. The second half of 2024 will see the continuation of existing and the introduction of new awareness building activities as we build up to the charity's 3rd match funding campaign planned for November. Further events in the now established scientific series of lectures will enable us to further expand the charity's role in educating the community on prevention and better management of JGDS. An important focus will be placed on developing the educational element of the engagement campaign in support of the new BRCA screening programme. EnsLJring the community is well informed, educated and supported through every step of their BRCA joumey is al the core of our work. Jnetics has now strengthened ils education team lo ensure that we continue to deliver on this core objective. Looking ahead, as we develop and adopt our new three-year plan over the next few months. we see the opportunity to build on our solid foundations lo improve our delivery, efficiency and effectiveness, together with great potential from our expanded panel and the opportunity lo move forward in our work in relation lo hereditary cancers. Engagement with and support from the community remain critical lo our success and continues to improve. We have seen a significant increase in awareness of the community in relation lo JGDS and the important role of our work, enabling us lo achieve our objectives more easily. Flnanclal revlew Principal sources of funding The charity receives most of ils funding from donations and was able lo claim gift aid where applicable.

JNETICS {A Company Limited by Guarantee) FOR THE YEAR ENDED 31 DECEMBER 2023 Rgsults for thg ygar The financial statements for the year are sel out in pages 1110 19. The Slalemenl of Financial Activities on page 11 reflects a surplus of £240.85412022- surplus of £154,608) for the year ending 2023. Reserves The charity aims to maintain free reserves sufficient to finance its operating costs for around 6 months. Reserves in excess of this amount are applied lo further the charity's objectives. The charity's reserves on 31 December 2023 amounted to £462, 18912022 - £221,335}, of which £437,56912022 - £203,335) related lo unrestricted funds and £24,62012022- £18,000) lo restricted funds. Structure, Governance and Management Jnelics I'the charity") is a company limited by guarantee INo.070872701 and a recognised English charity {No. 11349351, governed by its Memorandum and Articles of Association. The charity was incorporated as Jewish Genetic Disorders UK on 25 November 2009 and changed its name to Jnetics on 2 July2015. Appointment of Directors New Directors are nominated for appointment by the existing Directors. There is a Ihree-year tem for Directorship subject lo reappoinlmenl. Prior lo their appointment, new Directors would be familiar with the charity's values, its aims and objectives as well as ils day-lo-day operations. As part of their induction programme, new Directors are required lo understand their statutory responsibilities. Statement on Risk The Directors are assessing the major risks to which the charity is exposed on an ongoing basis and are estsblishing prO￿dureS to mitigate those that are identified as a result of these reviews. Office Bearers The Directors who served during the year and to the dale of this report were as follows.. A L Angel AMLeon L Blitz Drmziff Emay L Birnbaum Dr J Harris N Goldschneider Iresigned 21 August 2023} Trustees l Directors, responsibilities Company Law which is 81so applicable to charitable companies in England and Wales requires the directors, who are also Trustees of the company, lo prepare financi81 statements for each financial year which give a true and fair view of the stale of affairs of the company and of the results of the company for that year. In preparing those financial ststements, the direCtors￿ruSteeS are required to.. select suitable accounting policies and then apply them consistently., make judgements and estimates that are reasonable and prudent., and prepare the financial statements on the going con￿rn basis unless il is inappropriate to presume that the company will continue in business. The directorstrrustees are responsible for keeping proper accounting records which disclose with reasonable accuracy al any time the financial position of the company and lo enable them to ensure

JNETICS {A Company Limited by Guarantee) FOR THE YEAR ENDED 31 DECEMBER 2023 that the financial statements comply with the Companies Act 2006. They are also responsible for safeguarding the assets of the company and hen￿ for taking reasonable steps for the prevention and detection of fraud and other irregularities. Small company exemptions The above report has been prepared in accordance with the special provisions of Part 15 of the Companies Act 2006 relating to small companies. This report was approved by the Board of Trustees l Directors on by.. and signed on its behair A L Angel Director and Chalr

Independent Auditor's Report To the members of Jnetics Opinion We have audited the financial statements of Jnetics for the year ended 31 December 2023 which comprise the Statement of Financial Activities, the Balance Sheet, stslement of cash flows and the related notes. The financial reporting framework that has been applied in their preparation is applicable law and United Kingdom Accounting Standards, including Financial Reporting Standard 102.. The Financial Reporting Standard applicable in the UK and Republic of Ireland (United Kingdom Generally Accepted Auounling Practice). Opinion on financial statements In our opinion the financial statements.. give a true and fair view of the stale of the charitable company's affairs as at 31 December 2023 and of ils income and expendilure for the year then ended.. have been properly prepared in accordance with United Kingdom Generally Accepted Accounting Practice,. and have been prepared in accordance with the requirements of the Companies Act 2006. Basis for opinion We conducted our audit in accordan￿ with International Standards on Auditing IUKI {ISAs IUK}l and applicable law. Our responsibilities under those standards are further described in the Auditor's responsibilities for the audit of the financial slalemenls section of our report. We are independent of the Charity in accordan￿ with the ethical requirements that are relevant lo our audit of the financial statements in the UK, including the FRC'S Ethical Standard and we have fulfilled our other ethical responsibilities in ac¢ordanTr with these requirements. We believe that the audit eviden￿ we have obtained is sufficient and appropriate lo provide a basis for our opinion. Conclusions relating to going Concern In auditing the financial slatemenls, we have concluded that the trustees, use of the going concern basis of accounting in the preparation of the financial statements is appropriate. Based on the work we have performed, we have not identified any material uncertainties relating lo events or conditions that, individually or collectively, may cast significant doubt on the ¢harily's ability to continue as a going concern for a period of al least twelve months from when the financial statements are authorised for issue. Our responsibilities and the responsibilities of the directors with respect to going concern are described in the relevant sections of this report. Other information The trustees are responsible for the other infom)alion. The other information comprises the infomation included in the annual report other than the financial statements and our auditor's report Ihereon. Our opinion on the financial statements does not cover the other information and, except lo the extent otherwise expliciuy slated in our report, we do not express any form of assurance conclusion Iheoon. In connection with our audit of the finsncial stslemenls, our responsibility is lo read the other information and, in doing so, consider whether the other information is materially inconsislenl with the financial statements or our knowledge obtained in the audit or otherwise appears to be materially misstated. If we identify such material inconsistencies or apparent material misslalements, we are required lo determine whether there is a material misstslement in the financial stslements or a material misstslemenl of the other information. If, based on the work we have performed, we Conclude that there is a material misstatement of this other information, we are required to report that fact. We have nothing lo report in this regard.

Independent Auditor's Report To the members of Jnetics Opinion on other matter prescrib8d by the Companias Act 2006 In our opinion, based on the work undertaken in the course of the audit.. the information given in the trustees, report (incorporating the directors, report) for the financial year for which the financial statements are prepared is consislenl with the financial statements., and the trustees, report lincorporating the directors, report) has been prepared in accordance with applicable legal requirements. Matters on which we are required to report by exception In the light of the knowledge and understanding of the Charity and its environment obtained in the course of the audit, we have not identified material misstatements in the Trustees, Annual Report. We have nothing to report in respect of the following matters where the Companies Act 2006 requires us lo report to you if, in our opinion.. adequate accounting records have not been kept or returns adequate for our audit have not been received from branches not visited by us., or the financial statements are not in agreement wlh the accounting records and returns., or certain disclosures of Iruslees, remuneration specified by law are not made., or we have not received all the information and explanations we require for our audit. Responsibilities of the trustees As explained more fully in the Trustees, Responsibilities Statement, the trustees (who are also the directors of the charitable company for the purposes of company lawl are responsible for the preparation of the financial statements and for being satisfied that they give a true and fair view and for such internal control as they determine is necessary lo enable the preparation of financial statements that are free from material misslatemenl, whether due to fraud or error. In preparing the financial statements, the trustees are responsible for assessing the Charity's ability to continLJe as a going COn￿M, disclosing, as applicable, matters related lo going concern and using the going concern basis of accounting unless the trustees either intend lo liquidate the Charity or to cease operations, or have no realistic alternative but to do so. Our responsibilities for the audit of the financial statements Our objectives are to obtain reasonable assurance about whether the financial statements as a whole are free from material misstatement, whether due lo fraud or error, and to issue an auditor's report that includes our opinion. Reasonable assurance is a high level of assurance. but is not a guarantee that an audit conducted in accordance with ISAS IUKI will always delecl a material misslatemenl when il exists. Misstatements can arise from fraud or error and are considered material if, individually or in the aggregate, they could reasonably be expected lo influence the economic decisions of users taken on the basis of these financial statements. Irregularities, including fraud, are instances of non-compliance with laws and regulations. Vve design procedures in line with our responsibilities, outlined above, lo delecl material misstatements in respect of irregularities, including fraud. The extent to which our procedures are capable of detecting irregularities, including fraud are sel out below. In identifying and assessing risks of material misstatement in respect of irregularities, including fraud and non-compliance with laws and regulations, our procedures included the following.. We enquired of management, which included obtaining and reviewing supporting ocumenlalion, wncerning the charity's policies and prO￿dureS relating to.. identifying, evaluating, and complying with laws and regulations and whether they were aware of any instances of non-compliance., Delecling and responding lo the risks of fraud and whether they have knowledge of any actual, suspected, or alleged fraud.,

Independent Auditor's Report To the members of Jnetics The internal controls established to mitigate risks related to fraud or non-compliance with laws and regulations. We inspected the minutes of meetings of those charged with governan￿. We obtained an understsnding of the legal and regulatory framework that the charity operates in, focusing on Ihose laws and regulations that had a material effect on the financial statements or that had a fundamental effect on the operations of the charity from our professional and sector experience. We reviewed the financial stslemenl disclosures and lesled these to supporting documentation to assess compliance with applicable laws and regulations. We performed analytical procedures to identify any unusual or unexpected relationships that may indicate risks of material misslalemenl due to fraud. In addressing the risk of fraud through management override of controls, we tested the appropriateness of journal entries and other adjustments, assessed whether the judgements made in making accounting eslimales are indicative of a potential bias and tested significant tmnsactions that are unusual or those outside the normal course of business. A further description of our responsibilities for the audit of the financial statements is located on the Financial Reporting Councils website at- Iwww.frc.org.uklaudilorsresponsibililiesl. This description forms part of our auditor's report. Use of our report This report is made solely lo the charitable company's members, as a body, In accordance with Chapter 3 of Part 16 of the Companies Act 2006. Our audit work has been undertaken so that we might state to the charity's members those matters we are required to stale lo them in an auditorfs report and for no other purpose. To the fullest extent permitted by law, we do not a¢￿pt or assume responsibility to anyone other than the charity and the charity's members as a body, for our audit work, for this report, or for the opinions we have formed. Anthony Epton (Senior Statutory Auditor) for and on behalf of Goldwins Limited Statutory Auditor Chartered Accountants 75 Maygrove Road West Hampstead London NW6 2EG Date.. 1 August 2024 10

Jnetics Statement of financial activities {incorporating an income and expenditure account) For the year ended 31 December 2023 2023 Total funds 2022 Total funds Unrestricted funds Restricted funds Note Income from: Donations 100.337 100,337 50,495 Charitsble activities". Grants and appeal income ChallengelEvents Income Trusvscreening income Tributes and Celebrations Gala Dinner BRCA Investment income Total Income 810.624 40,077 68.921 1,038 10,000 820,624 40,077 68,921 1,038 606,264 13,880 70,400 2,043 79,889 18,000 80,112 80,112 1,508 1,112,617 1,508 1,022.505 90,112 840,972 Expenditure on: Raising funds Charitable activities 237,183 551.088 237,183 634,580 242,975 443,389 83,492 Total expendlture 788.271 83,492 871,763 686,364 Net income l {expenditure) before net gains I (losses) on Investments Net gains I Ilossesl on investments 234.234 6,620 240,854 154,608 Net incoma l (axpenditura) for the year 234,234 6,620 240,854 154,608 Transfers be￿een funds Net movement in funds 234.234 6,620 240,854 154,608 Reconciliation of funds- Total funds brought forward 203.335 18,000 221,335 66,727 Total funds carrled forward 437.569 24,620 462,189 221,335 All of the above results are derived from continuing activities. There were no other recognised gains or losses other than those stated above. The attached notes fom part of these financial slatemenls.

Jnetics Balance sheet As at 31 December 2023 2023 2023 2022 2022 Note Flxed assets.. Tangible assets 10 27,231 4,299 Current assets.. Debtors Cash al bank and in hand 11 34.022 651.246 685.268 11,701 438,789 450,490 Llabllltles.. Creditors.. amounts falling due within one year 12 250,310 233,454 Nat cuThent assets 434,958 217,036 Total net assets 462,189 221,335 Funds Restricted funds Unrestricted funds= General funds Totsl unrestricted funds 14 24,620 18,000 437.569 203,335 437.569 203,335 Totsl funds 462.189 221,335 The financial statements have beon prepared in accordance with the special provisions for small companies under Part15 of the Companies Act 2006. Approved by the trustees on and signed on their behalf by.. 15 July. 2024. AL Angel Tru$tsg Company roglslratlon no. 07087270 The attached notes form part of the financial ststements. 12

Jnetics Statement of cash flows For the year ended 31 December 2023 Note 2023 2022 Cash flows from operatlng actlvltles.. N•t tash provid•d by I lus•d in) op¥ratlng aetlvStl•s 241,225 228,022 Cash flows from investing activities.. Salel Ipurchasel of fixed assets 128,7681 16,4481 Ca$h provided by I lu$¢d inl investing activities 128.7681 16,4481 Change in cash and cash equivalents in the year 212,457 221,574 Cash and eash equivalents at the beginning of the y8ar 438,789 217,215 Cash and cash •quivalants at th• ènd of the year 651,246 438,789 al Reconciliation of net income I lexpenditurel to net Cash flow from operating activilies 2023 2022 Net Income I lexpendlturel for the reporting period las per the statement of financial activities) 240,854 154,608 Depreciation Ilncreasell decrease in debtors Increasel Idecreasel in creditors Net cash provided by I Iu5ed in) op•rating aetiviti•s 5,836 122,3211 16,856 2,637 18,046 52,731 241,225 228,022 bl Analysis of cash and cash equivalents At1 January 2023 Cash flows At 31 December 2023 Other changes Cash at bank and in hand 438,789 212,4S7 651,246 Totsl ¢a$h and ¢a$h equivalents 438,789 212,457 651,246 13

Jn•tl¢$ Notes to tha flnanclal statoments For thè year ended 31 D•cemb8r 2023 1 Accounting policies al Ba818 of pr&paratlon The financial statements have been prepared in accordance with Attounting and Reporting by Charities." SlÈtemenl of Recommend8d Practice applicable to charities preparing their accounts in accordance vAlh the Financial Reporbng Stsndard applicable in the UK and Republic of Ireland IFRS 102 efteclive 1 J8nuary 20151 . (Charities SORP FRS 1021 and the Companies Act 2006. Th& charit8Ne company me8ts the d&finilion of a public b8n8fit entity und&r FRS 102. A8s818 and liabllltles 8r8 Initially r8cogn188d al hislDfic81 cost or Iran8action value Unle￿ olh8rMS8 81aled in the r818vanl 8ecounting policy or note. bl Golng ¢onc8rn Th8 Im8tee8 consid&r that thère ar8 no material unc8rtaintie8 about the Charitable compan18 ability lo continue as a going concern. The Irus188s do nol consid&r that ther& are any 80urc8s ol eslimalion Uncer￿lnty al th& r&porting dal8 that hav& a significant risk of causing a material adiustm8nl lo th8 carrying 8mounls of assets 8nd liabilities within the nexl reporting period. I Income Income is recognised when the charity has enlitlemenl to the funds. any perfofm8nce condit￿n$ attached to the iricome have been tnel, it is probable thatthe incorne wll be received and that the atnount can be measured reliably. Income from govemtnent and other grants, whether 'tapital' grants or 'revenue' grants, is rectynised when the charity has enlitlernenl lo the funds, any perforTnance conditions Èttached lo the grÈnts hÈve been Tnel, il is probable that the incorne ￿ryI1 be r&teived and the Èmounl can btr msasuréd reliably and Is not dÈferr8d. Incomé r8c*ived In advan¢È for the provision of $p8¢ified serwice is deferred Jntil the criteria lor income recognition 8re mel. dl Intsrest r6c8lvabl8 Interest on funds held on depo8lt Included when receivable and the can be measured reliably by the tharlty,. this is norm811y upon notification of the int8rest P8id or payable by the bank. èl Furbd accounting General fun(Is 8re unrestricted fun(Is which are 8vailable for use at the discretion of the Trustees in the futher8ntr of Ihe general objectives of the charity and which h8ve nol been design8led for olher purposes. Restricted funds are donations and grants solely used for particular areas of th& charity's work or for specffic projects being undertaken by the charity. Expenditure Expenditure 15 recognised once Ihere is a legal or constructive obligation to make a payment lo a Ihird party. it is probable that se1118mÈnt will be required and the amount of the obligation Can bè mea8urÈd r￿l￿bly. Expenditure on raising funds compris& th& cost of donations mad&', 8xp8ndiiur8 on charitable a¢tiviti8s includ8 costs Incurred by the charity in deliv&ry of its 8Ctiviti8s and ser¢ic8s for ils beneficiaries. gl AJlo¢ation of 8LlPPOrt costs Support Cogts are th088 functlon8 that a8818t th& work of th8 charliy but do not (Jireclly und8rtak8 charitsbl8 aclivi11&8. Support costs include back oftice co818. finance, personnel, payroll and governance costs which 8UPPOrt the charity's aclivilies. These costs have been allocated between cost of raising funds and expenditure on Charitsble aclivilies. h) Tangible fixed assets Tangible fixed assets are stsled at cost or v8lualion less depreciation. Deprecyation is provided at rates calculated to wite do% the cost of each asset to ils estimated residual value over ts expected useful life. The deprecialion rates in use are as follows.. Cornpuler equipment Furniture 8nd Fillings 3 year8 Stralghl Ilna 4 years straight line il Debtors TraLle and other debtors 8re recognised al the settlement 8mounl due after 8ny trade discount offered. Prepaymenls are v8lued al the amount prepaid nel of any trade disGounls due. Il Cash at bank and in hand Cash at bank and cash in hand includes cash and short term h￿hlY liquid investtnent5 vAlh a short maturity of three rnDnths or léss from th& dat8 of a¢qul8ltlon Dr openlng Df th8 d&p0811 or similar account. kl Cr8dltors and provlslons Cr&ditors and provl8lcrf)s ar& ra￿gniSed wh8r& the charity has a pr8sent obligation r&8uiting from a p88t &v6nt that wlll probably result in th8 transfer of funLls to a third party and the amount tlue lo settle tt)e obligation can be measured or estim8t8d reliably. Creditors and provisions are norm81ty recognised at their setuement arllount after allowryng for any Ira(le discounts due. 14

Jnetics Notes to the flnanclal statements For the year ended 31 December 2023 2 D•t•llod ¢omparatlv•$ forih• $tstsmont of fln•n¢lal ¥¢fjvltlo8 2022 Unre$iri¢ted funds 2022 Designated funds 2022 Restricted funds 2022 Tot81 funds In¢omo from- Don3bons Charita￿e activities.. Grants and appeal income ChallengelEvents In¢ome Trususcreening income Tributes and Celebrations Gala Dinner 50.495 50.495 606.264 13.880 70.400 2.043 79.889 606.264 13.880 70.400 2.043 79.889 18,000 BRCA Interest 18.IN)O Totsl Income 822.972 18.(KlO 840.972 Exppnditure on- Chants￿e activities Raising funds Others 386.180 242.975 57.209 443.389 242.975 Total expenditure 629,155 57,209 686.364 Net Income l expendlture b￿Ore galns I Ilossèsl on1rt¥è8tmènts 193.817 139.2091 154.808 Tran$fers between fund¥ Net Income I lexpendlturel 2.825 19D.992 2,825 2,825 139.2091 154.6D8 Total funds brought foDfyard Total fund5 carried forward 2.825 57.209 18.IM)O 66.727 221,335 2D3.335 3 Incorn8 from donation8 and legacies 2023 Total hjnds 2022 Total funds Unrestrlcted nds Restricted funds Domtions Gift Ald 44,062 56,275 100.337 44,062 56,275 100.337 44.062 56.275 100.337 4 Incom• from eharltablè ftctlvltlos 2023 Tot¥1 lunds 2022 Total fund$ Unr•$trl¢t•d fijnds R*¥tri¢t6d funds Grants and appeal income ChallengdEvents Income NHS Furtding In¢omt T￿svsCr￿e￿i￿g income Chai Income Tributes and Celebrations G¥la Dinner Total Income from charltable advltles B10,624 40,077 10,000 B20,624 40,077 50,850 68,921 29,262 1,038 606.264 13.880 18.000 70.400 50,850 68,921 29,262 1,03B 2.043 79.889 5 In¢omo from ItWO¥tmot)t8 2023 Total nds 2022 TDLqI funds Unrestrlcted funds Restrlcted fundA Bank interest 1,508 1,508 1,508 1,508 15

Jnetics Notes to the financial ststements For the year ended 31 December 2023 Analysis of expenditure Fundralsln costs Charltablè activities Su 2023 Total 2022 Total costs Staff costs Screening Database Insuran Office costs Telephone Post Sundry AccoLJntancy Consultancy Bank and Online Fees Legal and Professional Subscriptions Depreciation Website Awareness Meetingttravel Fundraising PR Costs Genetic Counselling Costs Gala Dinner Expenses Independent examination fees Loss&s on ¢urren¢y exchange 302.901 240.728 3,770 1,850 30,258 1,712 302,901 240,728 3,770 1,850 30,258 1,712 5,885 8,018 14,890 9,060 3,777 611 484 5,836 6,479 50,490 1,700 74,214 13,725 90,726 220,519 156,924 3,457 1,248 19,935 1,363 2,178 4,659 14,088 9,605 2,705 361 350 2,637 21,036 39,757 1,739 29,819 5,885 8,018 14,890 9,060 3,777 611 484 5,836 6,479 50,490 1,700 74,214 13,725 90.726 89,235 47,846 3,360 13,543 686,364 4,800 4,800 151 871,763 151 237,183 581.219 53,361 Support costs 53,361 153,361} Total gxp8nditur8 2023 237,183 634,580 871,763 Total expenditure 2022 686,3 686,364 Of the total expenditure, £788,271 was unrestricted12022.' £629,155) and £83,492 was restricted12022 £57,209). 16

JnetlC5 Notès to th• flnanelal stat•mènts For the year ended 31 De¢ember 2023 Net inccme I lexpenditurelforthe year This Is slated aftercharging I Icreditingl.. 2023 2022 OtprtrtyaiiDn Independent examiner's f&s net of VAT Independent auditor's fees net of VAT 5,836 2.637 2,800 4,000 Analy818 of Siaff ¢08ts, tlil8to6 r6munor8tlon and oxpon888, and th6 ¢08t of kay ma￿96M￿nI por8Othn81 Staff costs were as follows.. 2023 2022 Salaries and wages Soci21 security cosis Employer's conlribulion lo defined conlnbulion pensh)n schemes other staff¢osts 271,560 22,919 5,148 3,276 302,901 199.105 4.283 1.020 220,519 one em￿oyee earned over È60,000 in the yeAr12022.' 11. The total 8mpIoy8e benefits including Employer's NIC and conthbutions of the key management personnel were £82,571 I2022.- £82.0911. No charity Irustses were paid or received any olh8r benefits froTn eTnployment with the tharily in the year 12022.- £nill netherwer8 Ihey reimbursed 8xppnses during th8 y8ar12022". £nill. Staff numbors The average numberof empk)yees (head count based on number of staff employed) during the yearwas asfolk)ws'. 2023 2022 Charflable 8¢Uvilles Taxatlon The Gharilable company is exempt from corporation tax as all its income is charitable and is ap￿led for charitable purposes. 10 Tanglble fixed assets Furniture & fittings Equipment Total C08t Al the start of the year Aadltions In year Disposals In year Al the end of the year 6,912 22,316 11,808 6.452 1B,720 28,768 20,228 18.260 47,488 OtprB¢iation Al the start of the year Charge for the year 6912 2,864 14,421 5,836 2.972 Al the end of the ye8r 9,776 10.481 20,257 Net book value At the end olthe year Al the start of the year 4,299 4.299 17

JnetlC5 Notès to th• flnanelal stat•mènts For the year ended 31 De¢ember 2023 Oebtors 2023 2022 Trade Debtors Gift Aid D8blor AccTued income Prepa5Then15 Oeposits 5,076 1.800 4.556 19,524 3,677 1,668 34,022 12 Creditors.. arnounts falling due within one year 2023 2D22 Trade creditors Taxation and social security Pension Prepaid income Accruals Oèlèrred inumè 189,583 T,685 1,308 21,000 30,734 122.858 6.440 1.075 78,960 3,000 233.454 250,310 Deferred Income 2023 2022 Balan¢e ¥1 the beginning of ihe year Amount rtrlea$8d to in¢omtr in th• ye8r Amount deferred in Ihe yesr 8alance al Ihe end of the year 3,000 13,0001 17.562 117.5621 3.000 3,000 O•lerred inctsrt r•pr&sents grants r•¢elved 81 tho end of th8 18x yèar whith 8r8 tnllrely forihe purpo of prolo¢t¥ which stsrt ftor Iha ènd of thè 2022-23 ytr8r. Tho daiail of Ih6s0 will bt rèported in Ihtr $ub$aqutni ytar. 13 Analysis of netassets tse￿een fvnd5 Unrestricted Designated Restricted funds funds funds Toial funds T8ngible flxed assets Nel CU￿ent assets Net assets at the end of the year 27,231 410.338 27,231 Analysis of nel 8ssets between funds*rior ye8r Unrestricted De￿gnated funds funds Restricted funds Total funds Tangible fixed assets Net cutrenl assets Net assets atthe end of the year 4.299 199,036 4.299 217,036 18.000 18

JnetlC5 Notès to th• flnanelal stat•mènts For the year ended 31 De¢ember 2023 14 lal Movomonts in funds Incoming Atthe startof resources & the year gains Outgoing resources Atthe end of the year &10ssPS Transfers Restricted funds= BRCA Project 18,ODO 90,112 183,4921 24,620 Total r8¥trf¢tsd funds 18.000 90.112 83.492 24.620 Unrestrlcted funds.. General funds 203,335 203,335 1,022,505 1022,505 178B,2711 788,271 437,569 437,569 Ttstal unrè8tri¢tad funds 141bl Movements in funds-prior year Incoming Oulooing resources & reSoUr￿S & gains losses At the slartof the year Al the end of the year T￿nSferS Restricted funds. BRCA Proje¢l GENEius 57.209 156.9781 18.OOQ 103.000 157.2091 18.000 151.239 Total rtrgiriciad funds 231 121,000 254,470 151.239 18,000 Unresiri¢tod funds". De$ign¥led fund$ Genaral funds 12.8251 12.343 2.825 12,8251 822.972 1629.1551 203.335 Total unrestricted funds 9.518 822,972 629,155 203,335 Purpose of restricted funds BRCA Pro e¢t'. To fund a proieci io develop key Information resources and r8ise 8w8reness ￿l8￿ng io BRCA asso¢i8tsd ¢an¢ers among the 81 in¢¢8sed rlsk, Jewish popuLgiion In the UK with the alm of improvlng the awarenests. diagnosis and m8n$gement of these ¢8n*rs. 15 Legal status of the char6ty The chariiy 1$ a company limi￿￿ by gu8ranl$e and h8$ no Sha￿ ¢apit¥l. E8ch m$mb6r is Ibble 10 unwibule ¥ sum not &%¢eeding £1 in the eveni of the Charity b61ng wound Jp. 16 Related partytransactions During the year, the charity received total donat￿nS of £18.01612022.. t45,1801 from the tsuslees. 19