2025-12-31-accounts

Trustees Report for 2025 Accounts

KF: NHS England meeting for Pembro for ATC pts

KF: Working party meeting for ION paper

KF: Letter for David Hamilton for thy3f patients

KF: Pembro meeting

KF: Thyroid group meeting NCRI

KF: Omar Hilmi funding discussion pt eye, suggest BTF part fund

KF: Call with Neil and Nikita re WTC Boston – BTCT to part fund Nikita’s travel + subsistence. Nikita to be responsible for QR code cards and ensuring Molly’s film shown on monitors at venue.

KF: New patient information film ( Molly’s film) accepted for WTC and Nikita to represent BTCT

KF: HOT Trial meeting

KF: Lauren Hullett

KF: Investigated showing new patient information film in Newcastle to a select audience

KF: Selpercatinib submission for SMC

KF: Individualisation of RAI room for Ollie at NCCC

SF: Preparation for “Rarity Life Magazine” article on BTCT

KF: HoT trial meeting

KF: Discussion with Amy Barnes (radiographer in Leicester) regarding AI support for U/S scans (basically underlining what we already know about KOIOS software.

KF: Mollys film to be shown at World Congress Boston and confirmed sponsorship of Dr Nikita Chander as BTCT representative. Nikita to be responsible for dissemination of new QR code cards to attendees.

KF: Facilitated patient with rare gene fusion for filming

KF: Facilitated support for Northampton patient who wasn’t given any information at diagnosis

KF: Press release for ION

KF: BAETS webinar

KF: SMC submission and meeting for Selpercatinib

KF: Selpercatinib PACE meeting for Scotland

KF: NCRI meeting - discussion regarding whether ‘fat jabs’ were appropriate for thyroid cancer pts ?

KF: ION documents finalized

KF: New trial coming Dr Carlos Wong AI – BTCT offered to help with patient involvement and information

KF: Protracted NCRI meeting. Discussions include both national and international research trials.

KF: further discussion on GLP1 agonists and thyroid cancer pt information

KF: Press re ION trial results

KF: Family support for 9 year old with lung metastases

SF: Rarity Life Magazine article published

KF: First meeting for new generic pt info film to replace “Thyroid Cancer uncovered”

Niki Chander attended World CONGRESS with “My Thyroid and Me” young patient information film (Molly’s film)

KF: Discussion regarding upgrades to paediatric rooms at The Christie and Glasgow

KF: Further work with Play Team at Christie to do paediatric rooms and also links for Glasgow established

KF: Mollys film to be broadcast on the BAETS APP for conference 2025

KF: Presentation for Imperial College patients

KF: meeting to discuss new nodule investigation guidelines

KF: Glasgow paediatric patient room

KF: Alicja’s PHD project published in BMJ – “Factors affecting thyroid cancer survivors”

KF: further support for Balraj’s family wrt ongoing treatment

KF: Discussion with Dr Carlos King Ho Wong regarding an AI development aid in thyroid cancer decision making

KF: NorthEast Enterprise Award

KF: Further discussions with Amy Barnes, Sheffield NIHR re. thyroid nodules AI to reduce number of FNAS

KF: Molly’s film shortlisted for Smiley film awards

KF: Molly’s film shortlisted for National TV film awards

KF: Meeting with Geroge Mochloulis and Carian Cruz regarding thermal ablation vs surgery for micro carcinomas

Thermal Ablation v surgery for micropap ca

KF: Wanting multi centre study BTCT to support with patient group , me to be stakeholder ,they want NIHR grant .

KF: Meeting with Neil Sharma to discuss trial looking at surveillance vs surgery for low risk tc

AH: patient mediator offering support to patients on Thursdays through email, text, virtual meetings and telephone. Attends virtual and live meetings pertinent to her position in BTCT. Assists in local RAI room Individualisation for young patients.

SF: Administrator for BTCT, responsible for maintaining sufficient supplies of QR code cards, leaflets, stationery and advertising/ awareness supplies; liaising with national centres to deliver BTCT patient information media; accounts and finance; charity commission and HMRC governance; fundraising; IT; lodge bookings and maintenance; involvement in grant submissions and virtual meetings pertinent to his role.

Abbreviations:

KF	Kate Farnell
SF	Steven Farnell
AH	Amy Horton
EP	Euan Preston
BTCT	Butterfly Thyroid Cancer Trust
SMC	Scottish Medical Committee
NICE	National Institute for Clinical Excellence
D & T	Dabrafenib & Trametinib
TC	Thyroid Cancer
UCLH	University College London Hospitals
BAETS	British Association of Endocrine Thyroid Surgeons
ION	Iodine or Not
USS	Ultrasound Scan
PPI	Patient & Public Involvement
BTF	British Thyroid Foundation
BTA	British Thyroid Association
RAI	Radioactive Iodine Treatment
TYA	Teenage & Young Adult cancers
NuTH	Newcastle upon Tyne Hospitals charity
NIHR	National Institute for Health and Care Research
HOT	Hemi or Not
ATC	Advanced Thyroid Cancer
WTC	World Thyroid Cancer Congress
NCCC	Northern Cancer Care Centre
JW	Jon Wadsley
KG	Kate Garcez
KN	Kate Newbold
CRUK	Cancer Research UK

BurrERFLY THYROID CANCER TRUST Rogistered Charity number: 1108932 FINANCIAL ACCOUNTS FOR THE YEAR ENDED 31ST DECEMBER 2025 DRAYCOTT & KIRK CHARTERED CERTIFIED ACCOUNTANTS 92 Westgate Guisborough Cleveland TS14 6AP

BUThERFLY THYROID CANCER TRUST SUPPORT GROUP INFORMATION YEAR ENDED 31 DECEMBER 2025 Trustses: Mr F St8fft)rd F.R.C.S Mr J Salter Mr D Farnell Bsc rs D Golighuy Mrs R Newlon Addres5 PO Box 205 RovAands Gill Tyme & Wear NE39 2WX Bankeys Lloyds TSB Wesl Street Gateshead Accountants Draycotl & Ifjrk LLP Chartered Cedified A¢￿Un￿ntS Cleveland HoL￿e 92 Westgate Guisborough CLEVELAND TS14 6AP Reg. charity no. 1108932 Page 1

Ind•pondent Examlnerfs Report lo the Trustees of Butterfly Thyrold ¢ancerTrust I report on the accounts of the charity for the year ended 31 De¢emtxr 2025 are set out on pages 3 to 6 Re$pe¢tive responsibllfjiies of iTUStèes and examlner The chanws trustees a￿ reswnsible for the preparab.on of the accounts. The chaiTty's trustees eonsider th8t an audit is not required for this year under Se￿￿ 144121 of the Charitses Act 2011 (the 2011 Acll and that an independent examinat￿Th is needed. It is my responsitylty to". exarnine the accounts under sectw 145 01 the 2011 ACL" follow the procedu￿ Lgid don in the general 05￿￿10nS gven by th8 Charity Commission under section 14515llbl of the 2011 Act- and state whether parbDJlar matters have come to my attention. Basis ot independent ex3mlne¢s report My examination bWd5 carried out in &￿rdance wilh the ger￿ra1 Directi￿$ 9iven b"1 the Charity Commission. An examination i￿ludeS a rewew of the accountsng re<x)rds kept by the charty and 3 comparison of the acrx)unts presented wlh thtsse records. K also indudes cwS1derat￿n of any unusual itèms )r disdosures in the account5, and seeknng explanations frorn you as trusiees con￿mIng any such mattets. The prO￿dU￿$ undertaken do not provide all the ev￿en￿ that would be required in an audit and ¢onsequenUy no opinion is given as to whether the awounts present a and fair viewf and Ihe re¢￿ is Iirnited lo those tnatiers se out ￿ the stslewnent below. Independent exzminels statsment In Connection wth my examinab"on. matier has corne to my aitention.. which gNes rne rea$￿able cause to believe Ihat. in any material respect. the requiretnents.. to keep a¢¢ounting re(xYds in accordance with se¢ti(ffi 130 of U)e 20. 1 ACL and to prepare accwnts wh￿h vAth the atsx)unting records ard ts)mrAy ￿th Ihe acc(yJnts"ng requirements of Ihe 2011 Act have not been met.. or to which. in my opin￿n. attenlwjn shwkl be draTt in ¢)rder to enable a prope. understr￿ing of the accounts lo be read)ed. C N Mason Charter8d ce￿fiedACc0u￿￿nI Dray¢oll & LLP Clevelanrl House 92 Weslgate Guisborough Cleveland TSt4 6AP Dète

BUTTERFLY THYROID CANCER TRUST TRUSTEES ANNUAL REPORT FOR THE YEAR ENDED 31ST DECEMBER 2025 istered chari numb8r 1108932 Charit￿5 prfnclpal address PO Box 205 Rowlands Gill & Wear NE39 2WX Narn•s of Charity tru$to05 who manage the tharity Mr F Slafford F.R.C.S Mr5 0 Golight klr J Salter Mr D Famell Ssc Mrs R Netyn Structure. govèmance and manayèmtrnt Goveming docurnent Tntst D￿d ConslilutKJn Tw5t Trustee Se￿tr￿ rnethod5 Twu#e￿ S￿￿t&d ty ￿8119 Tru&le88 Objectives and activitie5 To allevrdle Ihe physical. p5ychdogical OTfinanoa drfficuthes ￿ hardship of tople 8fl8cl&1 by thyroid cgncer. To promote e(f￿atiOn about thyroKI cancer io membe[5 of the wblic 81 latge. The charity provides.. A ￿ed￿al￿ tdeph[K￿ helpline. Holidays A buddy System Awareness Even's Palienl infotmaiion sbks Research Grants Webstle Palnt infom)atKn OVD On site dinical supF Suppressi( Catts H05ptsI Conferentè Pressntations Facilitates palEnl intr￿1￿5 RAI r￿[￿ access￿e$ Atlends thYr￿d tsncÈr (J)nfÈrencÈs ClintAI Trials Jiqsory role Neith of pabent SUPkVt cwtac Patiènt infom)ati()n advisory ro58 RAI r(K>m renovati￿SIrwdrnp NICE TC cornmi55ioner- nati{￿1 TC guHlelines Provision of IM>liday Tesple a￿0￿m￿tion pat￿ni InfcyMa￿) Manag8meni posilw for S¢ottish Thyrmd Lan￿r NetwDrk Vdunteers and 9mup members we involveo ￿ fuTrJ raisiro ackn¥ril*s. They altend anc wovtde infoxrnatK>n star￿S at rÈlevant eonferertts. Ptye 38

TTERFLYTHVTr 10 CANCER TRUST TRUSTEES ANNUAL REPORT FOR THE YEAR ENDED 31ST DECEMBER 2t125 hk•v•rn•nts und•rtskn forth blk b•n•fft kn r•latloDtoth• KF.. MHS Engignd rtreing fDrPthyvtsATCVS KF.. Workry party n￿tyng for ION paper KF." L@tiorfoi David forthy3f patients KF.. Pembro rneeting KF.. ThyNd 9foup meetn9 NCRI KF. Omar Hilmi (und￿￿ d￿U55￿n ￿ eye. 5ug9e51 BTF partfw KF Cal with Nèd and Nikits iè WTC Boston- BTCT to P￿t￿j￿j Nts'¥tr￿d * Subsist￿. to be resp)nthloforQR ¢fylerxd5 and en5Uri 4dly's film irMJwn on monirrt at venue. KF.. New pèikni InformaDon rkn I kI0￿Y'S￿￿}x￿￿ WTC ar￿ NAa brewewl 8TCT KF." HOT Trial rneebn9 KF.. Lauren Hullell KF.. Investigated S￿￿n9 new p3kn1 rkn in N¢asOe io a sdecl aLthn KF-. Splpgr¢atinib Subms8k)n for SMC KF.. Individualisation ol W room IorlJlèAINCCC SF.. Preparation fLY-Rarity Lif9 k4aga2inè" on BTCT KF.. HOT trial meeti KF". DiSCuS8N)n ￿th W Banes in fvaundErfwdng %•￿tY￿ a1re•Jy krmw abNrt KOIOS g¢ftwarèl. KF." Mollys lilm to bè shovn) Cihwress Boslon 3￿j $rAY￿st1POrDr BT,=T rwe5entative. to b¢ responsiblg fDr dL3$9Minati￿ of nwQR ¢￿¢¢ardS lo alt￿￿90$. KF.. Farylilawd Dabenlwth rarn futhn forllrring KF.. FaQI￿ated supportlor Norulampton pabèni%%knvAsnlgr¥¢n any irdtyNthI at d￿0￿$ KF.. Press release for ION KF.. BAETS weknnar KF.. SMC submisgon ar￿ r￿eti￿ for$￿th KF." S￿pe1C3t￿ib PACE meebng for Smuan KF." NCRI meèting. diSCUSSk)n iegaitsing whethw Yatjabs. rts? KF". ION documents fnalize KF. Nwi irial co￿ng Or Ca￿￿8w(WAJ- BTCT ortered tobdpith ￿ti￿nt •l¥d￿nemaTrj inftin KF Protiatied NCRI mtttsng. Di5DY&s￿ns both nationalaTh r8searrtrA&. KF." furthErdiscv8sw SLPI agonistsaThJ ihyrowj piinf¢xmakn KF.. Press re ION rosutts KF." Family suppor1f0r9￿rp￿ luw metss SF." Rarity Lrfe mag￿lne arbde publis KF. First meetiro IIY Dew generic ot info 10 rep￿t￿h￿C•1 Nikl Chanderatte￿ed Wortd CONGRESSith"MyThymM1 kl8. IKWVsflml KF Disru$¢n rgardI￿ upgrades to paediatrK rowm alThe Chrisbe and GL3>J¢y KF.. Further workwilh Play Team alChnstio do paedkitrK rorTr5wJ¥so knks&yGlw eknhed KF. Moltys flrn ￿ be broadcasl on BAETSAPPftt¢(￿lerertt 2025 KF." Pr￿￿￿tin Imperial ediege patients KF." tn8tyThg to di%CuSS new Thr￿Ule InvestsgatKn gidelhgs KF.. Gksgow paediatric Patnt mom KF.. Aicja's PHD kyoied Pu￿lsh￿d in BKU-Faetors afteeting ty￿d wrvr•tyS" KF." further Supmfor 8alrajs family trèaknènt KF". DISeu$Sion Dr King Howoty warding 8rt￿ de¥etyj￿aid in th>TcJ de¢tsiM makr KF." NorthEasi Enierpnse Award KF." Further dts¢USs￿nS Amy 8arnes. sheffi￿ NWR ts. torethce roJmbpi(rf FNAS KF.. Molly's film lor Smiy Am KF.. Molly's film Sh(￿￿$%￿¥ tor Na1￿￿1 TV fikn KF.. Wanllng multi Cent￿ 8TCTtO 5UPPrytilh paliÈ￿t5rnty. ffe t0bestakeh0W.￿fjYwt NIHR gr8nl. KF." kIÈè￿fftg Nèil Shama ID d￿5$ al 5ur¥elLywvSSuryl<¢ky rtsk

BirrYERFLYTHYROfl CANCER TRUST TRUSTEES ANNUAL REPORT R THE YEAR ENDED TDE EIIBER Summa otthe mafj H.. pelrenl mediqÈ)roflerfrKJ Suoptrtto Thutsdaysthrnw emal. tèAt. mèthgsand and INe m¢eting$ Psthenlto pJsitv)n ￿ 8TCT. Asssts ￿ I￿1 r{￿￿ foryoury pabetts. SF.. AdminY&traknrfor 8TCT. respmgble for sufventsupfl￿s￿f1x¢ c￿e￿rts. ￿ar￿ts, sta1¥￿et￿ wfvEtbnyl8w8¢ness Suwlies. liaising With nabonal io BTCT Patient ￿f0￿￿￿tion trtdk. Ète￿ntS and fin3Th￿. chath. CDmmiSSiOll and HMRC goveErLancB". fundr¥iwn9". tT. Wge bookitt95 and rtwntsnanre." InvifvempniiigtÈMsthmtssH￿s ￿d¥1￿u￿ rthtsws wbnenl to his role. brovlatlons.. Kate FarThe11 Stev￿ Fam Arny HorlD Euan Presl Èuttwfy Th￿QKI Carw Tnk5t ScotD5h MedKal Comrnittee Na￿n￿l lnsti￿le forClinic ExcefAKe Oabralenib &Trar￿￿knib Thyi(xd CanC@r Uh￿￿￿1ty ¢¢iiègè LorRltr) Hospit Bnlrsh AssQLxal￿ ol ThIT<J k>dine or Not EP BTCT SMC ￿￿E D&T TC U¢LH BAETS ION uss ultrasou￿ Stan Pa1￿￿{& Pthlic Involvement Brrfa5h Th￿K* Favtsdatity) Brilish ThyroKfAssocKgt Radioactive Trealm Teenage & Young Newtasle w)on Tyne Hosptsts rjwity Naknona In$biute fot Heayth Re5earfh or NDI Ad¥anre# Car wor￿ Thyrokl c￿r¢0¥¥Jr￿s Cancercare Centre Jon Wadslèy Ka￿ GaTCÈz Kalè Néwbokrt CwwR9¥9arth UK BTF RAI TYA NUTH NIHR HOT ATC WTC NCCC Jw KG KN CRUK PwJ?3

r6LY YTrIYRUD CWXER TR FOR THE YEPA ENDE031ST D¢sitywÈdknnd¥ £10.00). Buttethy Lod9• £7.500- PatentSUFWrt e0MaLg t25.￿. thw9n&t6dlO a<kniiistrth0 ¢(6ts. ance ofttie rts0fv68 kn $[￿￿Tr ryéwtartdfwe F¥ll NaTh• Far￿ Trtr51ee )% L4.L P** 3d

YTHY 70.CQO 78.512 1.183 13.1YJ 141894 7e.512 1.1t3 13.1(9 1418É4 Gfft Ak# 1.614 17.134 S1.046 Dirt(llabl• exwthtyi• Payr¢U Pr0fKtsSKi￿ lees TeWc4ie 71228 43.035 43.ts Z013 1,71 1.377 1.X7 T.18 2.& 8.&11 Irtswarkce 3.424 1.￿7 M¢or & ¢￿tr R8Fw$ 3rKI marlenar 8.841 12 437 l>arls 6.6iS 1.9% Accountsncy Profft (? Deve￿￿ts0Th 23.6 167.a 187.421 1T3.233 {24 5271 791.￿7 124.:271 117.813 Total fur4$ 7.428 878,ll5

BurrERFLY THYROID CANCER TRUST BALANCE SHEET AS AT 31ST DECEMBER 2025 FIXED ASSETS Land & buildir,g5 Fixtur8s & e(yJipment 130.0511 3.46'3 153.0 1.677 CURRENT AS D&btors Bank Accolmls Cash In Hand 723,461 597 724.1)58 597 720,689 854.203 878,735 RRENT ABILITIES ETA ET 8S4208 878,735 ND Restricted Funds Un￿Stricted Funds Designated funds 786.7 87.428 791.307 87.428 854.2Jg 878,735 Those Financlal Slatem•nts war? approved by the Twste•s on e￿ Lt.L Slgn•d Full Name Oanièl Farnell Tru5teg Page S

ntin The ¢hartty conslituies a rMJbli¢ benvfit eTrtity 8s dofffted by FRS 102. The Ifftanrsl slale￿At￿ hale been prep8red in ac(YJFdance Accodnlirtg Rewrtsng by Charibe$." Statennl of Recornrn8nded pratt￿ applicab 10 chaiit¢s prepa￿￿ theK 8ruJunts in accotd8ncè wAh Ih? Fin&ncial Repurting S18né3rd 8ppIIcaoiÈ in Ihe UK of Ire￿[￿1 IFRS 1021155ued oft 16 Jufy 2014135 usxlat th1o￿h u4xJale bJHetin 1 publish 2 Fe￿ary 20161, the F¥)antsw Reportiw Stai dards appb(able in the United King￿VIn and Rep￿ of Ire12rK1 (FRS 10218nd LIK Generaty 2uxOail pfaEtKe as a apr￿￿$ from 1 January 2015. The has 8ppliaY U¥Klote 1 as put4bhed on 2 FeL¥uary2016 ar•J does hKbJe C8sh now s¢atemert Dn the #rounds apFty'ng FRS 102 SeclffJn 1 The F+nanaal staten￿niS are ¢)n a go￿9 coTKern basis undwtbe ty￿ corTrwil￿n. The @nantAal statements are rJr￿n1￿ Bi use IDr fi)d asset$ hepj for use by the Ghanly ar& 15% on strawam frJrFi¥tU￿5 and and 15% rèJur3n) brte (or I9￿d a￿] tyJlk1iws_ Ros8Thes Kthy.. The Irustee5 ha¥8 0)ft5kJerett Ihe ol needed kn othrlo mainipAn the orvjothg 8fATh￿tr$ ofthe Lanty The INslets c41￿￿jertha1 an reprESent￿g ts¥elTr*t months rA)5ts atE 8ttvsatle. 2a Grants 2025 syn￿￿5 70.0 70.000 Detals ofgr8nts are note 4. Pag8fj8

TfERFLYTHYROID CANCER TRUST Not￿ to theAccouTr)ts forthe rfod 31st Dvcember2025 2b GrJnts mad• Researth Grart. unP￿r$￿ofsh2ffj￿d ImprovemEnls to RAI rrKths 3T•n Ib￿ Flxed Assets Flxtures & Hofilla Bir 2.397 2.532 4.929 182.397 during IFpwiod 180.000 184.929 DepretyalvJn Bir Depreu3l￿n for Ihe DepreualK)n Clf 720 740 1.460 27.720 23. 51.410 49.950 Nel bwk at 31 Dec¢r(bw 2025 3.469 1￿.050 133.519 4 Furtds Transfer Openi rtsi fuThls Unrestrlct•d funds 791.307 142.894 766.780 Rostri¢ted funds Deslgnat¢d Funds 87.428 87.428 al Donati￿S frtym Sy[W￿ to be used fu Researth (>anl A¥Rrd, imwowements, bLrt eX￿U￿¥ety 5 Amaty$l$ ol lunJs by ass•ts Unrewc￿ Re5tsicterf DesKJn8W Total Fixed assets Current assets Current liabilibes 133.519 631261 133.519 720.639 87.428 766.780 87.428 8Y.2J8 6 Transactions with tvllstee's and Mnrcled Durifig the ￿ the￿ ¥¥as no trarwAon5 vnth Tntstees u ¢onntsJ P￿sOr￿ iNAudI￿ r￿￿rat1)n expense6. 7 Twustee Ind•mn Insuranc• During th8 yyar. Insurw¢w3s pwthased to th￿￿ty￿*(Y￿nMit￿ee wnStdÈf￿tt￿ thwr pwt 8 Control The uThJerlhè dlhe Tnèstees.

BurrERFLY THYROID CANCER TRUST Rogistered Charity number: 1108932 FINANCIAL ACCOUNTS FOR THE YEAR ENDED 31ST DECEMBER 2025 DRAYCOTT & KIRK CHARTERED CERTIFIED ACCOUNTANTS 92 Westgate Guisborough Cleveland TS14 6AP

BUThERFLY THYROID CANCER TRUST SUPPORT GROUP INFORMATION YEAR ENDED 31 DECEMBER 2025 Trustses: Mr F St8fft)rd F.R.C.S Mr J Salter Mr D Farnell Bsc rs D Golighuy Mrs R Newlon Addres5 PO Box 205 RovAands Gill Tyme & Wear NE39 2WX Bankeys Lloyds TSB Wesl Street Gateshead Accountants Draycotl & Ifjrk LLP Chartered Cedified A¢￿Un￿ntS Cleveland HoL￿e 92 Westgate Guisborough CLEVELAND TS14 6AP Reg. charity no. 1108932 Page 1

Ind•pondent Examlnerfs Report lo the Trustees of Butterfly Thyrold ¢ancerTrust I report on the accounts of the charity for the year ended 31 De¢emtxr 2025 are set out on pages 3 to 6 Re$pe¢tive responsibllfjiies of iTUStèes and examlner The chanws trustees a￿ reswnsible for the preparab.on of the accounts. The chaiTty's trustees eonsider th8t an audit is not required for this year under Se￿￿ 144121 of the Charitses Act 2011 (the 2011 Acll and that an independent examinat￿Th is needed. It is my responsitylty to". exarnine the accounts under sectw 145 01 the 2011 ACL" follow the procedu￿ Lgid don in the general 05￿￿10nS gven by th8 Charity Commission under section 14515llbl of the 2011 Act- and state whether parbDJlar matters have come to my attention. Basis ot independent ex3mlne¢s report My examination bWd5 carried out in &￿rdance wilh the ger￿ra1 Directi￿$ 9iven b"1 the Charity Commission. An examination i￿ludeS a rewew of the accountsng re<x)rds kept by the charty and 3 comparison of the acrx)unts presented wlh thtsse records. K also indudes cwS1derat￿n of any unusual itèms )r disdosures in the account5, and seeknng explanations frorn you as trusiees con￿mIng any such mattets. The prO￿dU￿$ undertaken do not provide all the ev￿en￿ that would be required in an audit and ¢onsequenUy no opinion is given as to whether the awounts present a and fair viewf and Ihe re¢￿ is Iirnited lo those tnatiers se out ￿ the stslewnent below. Independent exzminels statsment In Connection wth my examinab"on. matier has corne to my aitention.. which gNes rne rea$￿able cause to believe Ihat. in any material respect. the requiretnents.. to keep a¢¢ounting re(xYds in accordance with se¢ti(ffi 130 of U)e 20. 1 ACL and to prepare accwnts wh￿h vAth the atsx)unting records ard ts)mrAy ￿th Ihe acc(yJnts"ng requirements of Ihe 2011 Act have not been met.. or to which. in my opin￿n. attenlwjn shwkl be draTt in ¢)rder to enable a prope. understr￿ing of the accounts lo be read)ed. C N Mason Charter8d ce￿fiedACc0u￿￿nI Dray¢oll & LLP Clevelanrl House 92 Weslgate Guisborough Cleveland TSt4 6AP Dète

BUTTERFLY THYROID CANCER TRUST TRUSTEES ANNUAL REPORT FOR THE YEAR ENDED 31ST DECEMBER 2025 istered chari numb8r 1108932 Charit￿5 prfnclpal address PO Box 205 Rowlands Gill & Wear NE39 2WX Narn•s of Charity tru$to05 who manage the tharity Mr F Slafford F.R.C.S Mr5 0 Golight klr J Salter Mr D Famell Ssc Mrs R Netyn Structure. govèmance and manayèmtrnt Goveming docurnent Tntst D￿d ConslilutKJn Tw5t Trustee Se￿tr￿ rnethod5 Twu#e￿ S￿￿t&d ty ￿8119 Tru&le88 Objectives and activitie5 To allevrdle Ihe physical. p5ychdogical OTfinanoa drfficuthes ￿ hardship of tople 8fl8cl&1 by thyroid cgncer. To promote e(f￿atiOn about thyroKI cancer io membe[5 of the wblic 81 latge. The charity provides.. A ￿ed￿al￿ tdeph[K￿ helpline. Holidays A buddy System Awareness Even's Palienl infotmaiion sbks Research Grants Webstle Palnt infom)atKn OVD On site dinical supF Suppressi( Catts H05ptsI Conferentè Pressntations Facilitates palEnl intr￿1￿5 RAI r￿[￿ access￿e$ Atlends thYr￿d tsncÈr (J)nfÈrencÈs ClintAI Trials Jiqsory role Neith of pabent SUPkVt cwtac Patiènt infom)ati()n advisory ro58 RAI r(K>m renovati￿SIrwdrnp NICE TC cornmi55ioner- nati{￿1 TC guHlelines Provision of IM>liday Tesple a￿0￿m￿tion pat￿ni InfcyMa￿) Manag8meni posilw for S¢ottish Thyrmd Lan￿r NetwDrk Vdunteers and 9mup members we involveo ￿ fuTrJ raisiro ackn¥ril*s. They altend anc wovtde infoxrnatK>n star￿S at rÈlevant eonferertts. Ptye 38

TTERFLYTHVTr 10 CANCER TRUST TRUSTEES ANNUAL REPORT FOR THE YEAR ENDED 31ST DECEMBER 2t125 hk•v•rn•nts und•rtskn forth blk b•n•fft kn r•latloDtoth• KF.. MHS Engignd rtreing fDrPthyvtsATCVS KF.. Workry party n￿tyng for ION paper KF." L@tiorfoi David forthy3f patients KF.. Pembro rneeting KF.. ThyNd 9foup meetn9 NCRI KF. Omar Hilmi (und￿￿ d￿U55￿n ￿ eye. 5ug9e51 BTF partfw KF Cal with Nèd and Nikits iè WTC Boston- BTCT to P￿t￿j￿j Nts'¥tr￿d * Subsist￿. to be resp)nthloforQR ¢fylerxd5 and en5Uri 4dly's film irMJwn on monirrt at venue. KF.. New pèikni InformaDon rkn I kI0￿Y'S￿￿}x￿￿ WTC ar￿ NAa brewewl 8TCT KF." HOT Trial rneebn9 KF.. Lauren Hullell KF.. Investigated S￿￿n9 new p3kn1 rkn in N¢asOe io a sdecl aLthn KF-. Splpgr¢atinib Subms8k)n for SMC KF.. Individualisation ol W room IorlJlèAINCCC SF.. Preparation fLY-Rarity Lif9 k4aga2inè" on BTCT KF.. HOT trial meeti KF". DiSCuS8N)n ￿th W Banes in fvaundErfwdng %•￿tY￿ a1re•Jy krmw abNrt KOIOS g¢ftwarèl. KF." Mollys lilm to bè shovn) Cihwress Boslon 3￿j $rAY￿st1POrDr BT,=T rwe5entative. to b¢ responsiblg fDr dL3$9Minati￿ of nwQR ¢￿¢¢ardS lo alt￿￿90$. KF.. Farylilawd Dabenlwth rarn futhn forllrring KF.. FaQI￿ated supportlor Norulampton pabèni%%knvAsnlgr¥¢n any irdtyNthI at d￿0￿$ KF.. Press release for ION KF.. BAETS weknnar KF.. SMC submisgon ar￿ r￿eti￿ for$￿th KF." S￿pe1C3t￿ib PACE meebng for Smuan KF." NCRI meèting. diSCUSSk)n iegaitsing whethw Yatjabs. rts? KF". ION documents fnalize KF. Nwi irial co￿ng Or Ca￿￿8w(WAJ- BTCT ortered tobdpith ￿ti￿nt •l¥d￿nemaTrj inftin KF Protiatied NCRI mtttsng. Di5DY&s￿ns both nationalaTh r8searrtrA&. KF." furthErdiscv8sw SLPI agonistsaThJ ihyrowj piinf¢xmakn KF.. Press re ION rosutts KF." Family suppor1f0r9￿rp￿ luw metss SF." Rarity Lrfe mag￿lne arbde publis KF. First meetiro IIY Dew generic ot info 10 rep￿t￿h￿C•1 Nikl Chanderatte￿ed Wortd CONGRESSith"MyThymM1 kl8. IKWVsflml KF Disru$¢n rgardI￿ upgrades to paediatrK rowm alThe Chrisbe and GL3>J¢y KF.. Further workwilh Play Team alChnstio do paedkitrK rorTr5wJ¥so knks&yGlw eknhed KF. Moltys flrn ￿ be broadcasl on BAETSAPPftt¢(￿lerertt 2025 KF." Pr￿￿￿tin Imperial ediege patients KF." tn8tyThg to di%CuSS new Thr￿Ule InvestsgatKn gidelhgs KF.. Gksgow paediatric Patnt mom KF.. Aicja's PHD kyoied Pu￿lsh￿d in BKU-Faetors afteeting ty￿d wrvr•tyS" KF." further Supmfor 8alrajs family trèaknènt KF". DISeu$Sion Dr King Howoty warding 8rt￿ de¥etyj￿aid in th>TcJ de¢tsiM makr KF." NorthEasi Enierpnse Award KF." Further dts¢USs￿nS Amy 8arnes. sheffi￿ NWR ts. torethce roJmbpi(rf FNAS KF.. Molly's film lor Smiy Am KF.. Molly's film Sh(￿￿$%￿¥ tor Na1￿￿1 TV fikn KF.. Wanllng multi Cent￿ 8TCTtO 5UPPrytilh paliÈ￿t5rnty. ffe t0bestakeh0W.￿fjYwt NIHR gr8nl. KF." kIÈè￿fftg Nèil Shama ID d￿5$ al 5ur¥elLywvSSuryl<¢ky rtsk

BirrYERFLYTHYROfl CANCER TRUST TRUSTEES ANNUAL REPORT R THE YEAR ENDED TDE EIIBER Summa otthe mafj H.. pelrenl mediqÈ)roflerfrKJ Suoptrtto Thutsdaysthrnw emal. tèAt. mèthgsand and INe m¢eting$ Psthenlto pJsitv)n ￿ 8TCT. Asssts ￿ I￿1 r{￿￿ foryoury pabetts. SF.. AdminY&traknrfor 8TCT. respmgble for sufventsupfl￿s￿f1x¢ c￿e￿rts. ￿ar￿ts, sta1¥￿et￿ wfvEtbnyl8w8¢ness Suwlies. liaising With nabonal io BTCT Patient ￿f0￿￿￿tion trtdk. Ète￿ntS and fin3Th￿. chath. CDmmiSSiOll and HMRC goveErLancB". fundr¥iwn9". tT. Wge bookitt95 and rtwntsnanre." InvifvempniiigtÈMsthmtssH￿s ￿d¥1￿u￿ rthtsws wbnenl to his role. brovlatlons.. Kate FarThe11 Stev￿ Fam Arny HorlD Euan Presl Èuttwfy Th￿QKI Carw Tnk5t ScotD5h MedKal Comrnittee Na￿n￿l lnsti￿le forClinic ExcefAKe Oabralenib &Trar￿￿knib Thyi(xd CanC@r Uh￿￿￿1ty ¢¢iiègè LorRltr) Hospit Bnlrsh AssQLxal￿ ol ThIT<J k>dine or Not EP BTCT SMC ￿￿E D&T TC U¢LH BAETS ION uss ultrasou￿ Stan Pa1￿￿{& Pthlic Involvement Brrfa5h Th￿K* Favtsdatity) Brilish ThyroKfAssocKgt Radioactive Trealm Teenage & Young Newtasle w)on Tyne Hosptsts rjwity Naknona In$biute fot Heayth Re5earfh or NDI Ad¥anre# Car wor￿ Thyrokl c￿r¢0¥¥Jr￿s Cancercare Centre Jon Wadslèy Ka￿ GaTCÈz Kalè Néwbokrt CwwR9¥9arth UK BTF RAI TYA NUTH NIHR HOT ATC WTC NCCC Jw KG KN CRUK PwJ?3

r6LY YTrIYRUD CWXER TR FOR THE YEPA ENDE031ST D¢sitywÈdknnd¥ £10.00). Buttethy Lod9• £7.500- PatentSUFWrt e0MaLg t25.￿. thw9n&t6dlO a<kniiistrth0 ¢(6ts. ance ofttie rts0fv68 kn $[￿￿Tr ryéwtartdfwe F¥ll NaTh• Far￿ Trtr51ee )% L4.L P** 3d

YTHY 70.CQO 78.512 1.183 13.1YJ 141894 7e.512 1.1t3 13.1(9 1418É4 Gfft Ak# 1.614 17.134 S1.046 Dirt(llabl• exwthtyi• Payr¢U Pr0fKtsSKi￿ lees TeWc4ie 71228 43.035 43.ts Z013 1,71 1.377 1.X7 T.18 2.& 8.&11 Irtswarkce 3.424 1.￿7 M¢or & ¢￿tr R8Fw$ 3rKI marlenar 8.841 12 437 l>arls 6.6iS 1.9% Accountsncy Profft (? Deve￿￿ts0Th 23.6 167.a 187.421 1T3.233 {24 5271 791.￿7 124.:271 117.813 Total fur4$ 7.428 878,ll5

BurrERFLY THYROID CANCER TRUST BALANCE SHEET AS AT 31ST DECEMBER 2025 FIXED ASSETS Land & buildir,g5 Fixtur8s & e(yJipment 130.0511 3.46'3 153.0 1.677 CURRENT AS D&btors Bank Accolmls Cash In Hand 723,461 597 724.1)58 597 720,689 854.203 878,735 RRENT ABILITIES ETA ET 8S4208 878,735 ND Restricted Funds Un￿Stricted Funds Designated funds 786.7 87.428 791.307 87.428 854.2Jg 878,735 Those Financlal Slatem•nts war? approved by the Twste•s on e￿ Lt.L Slgn•d Full Name Oanièl Farnell Tru5teg Page S

ntin The ¢hartty conslituies a rMJbli¢ benvfit eTrtity 8s dofffted by FRS 102. The Ifftanrsl slale￿At￿ hale been prep8red in ac(YJFdance Accodnlirtg Rewrtsng by Charibe$." Statennl of Recornrn8nded pratt￿ applicab 10 chaiit¢s prepa￿￿ theK 8ruJunts in accotd8ncè wAh Ih? Fin&ncial Repurting S18né3rd 8ppIIcaoiÈ in Ihe UK of Ire￿[￿1 IFRS 1021155ued oft 16 Jufy 2014135 usxlat th1o￿h u4xJale bJHetin 1 publish 2 Fe￿ary 20161, the F¥)antsw Reportiw Stai dards appb(able in the United King￿VIn and Rep￿ of Ire12rK1 (FRS 10218nd LIK Generaty 2uxOail pfaEtKe as a apr￿￿$ from 1 January 2015. The has 8ppliaY U¥Klote 1 as put4bhed on 2 FeL¥uary2016 ar•J does hKbJe C8sh now s¢atemert Dn the #rounds apFty'ng FRS 102 SeclffJn 1 The F+nanaal staten￿niS are ¢)n a go￿9 coTKern basis undwtbe ty￿ corTrwil￿n. The @nantAal statements are rJr￿n1￿ Bi use IDr fi)d asset$ hepj for use by the Ghanly ar& 15% on strawam frJrFi¥tU￿5 and and 15% rèJur3n) brte (or I9￿d a￿] tyJlk1iws_ Ros8Thes Kthy.. The Irustee5 ha¥8 0)ft5kJerett Ihe ol needed kn othrlo mainipAn the orvjothg 8fATh￿tr$ ofthe Lanty The INslets c41￿￿jertha1 an reprESent￿g ts¥elTr*t months rA)5ts atE 8ttvsatle. 2a Grants 2025 syn￿￿5 70.0 70.000 Detals ofgr8nts are note 4. Pag8fj8

TfERFLYTHYROID CANCER TRUST Not￿ to theAccouTr)ts forthe rfod 31st Dvcember2025 2b GrJnts mad• Researth Grart. unP￿r$￿ofsh2ffj￿d ImprovemEnls to RAI rrKths 3T•n Ib￿ Flxed Assets Flxtures & Hofilla Bir 2.397 2.532 4.929 182.397 during IFpwiod 180.000 184.929 DepretyalvJn Bir Depreu3l￿n for Ihe DepreualK)n Clf 720 740 1.460 27.720 23. 51.410 49.950 Nel bwk at 31 Dec¢r(bw 2025 3.469 1￿.050 133.519 4 Furtds Transfer Openi rtsi fuThls Unrestrlct•d funds 791.307 142.894 766.780 Rostri¢ted funds Deslgnat¢d Funds 87.428 87.428 al Donati￿S frtym Sy[W￿ to be used fu Researth (>anl A¥Rrd, imwowements, bLrt eX￿U￿¥ety 5 Amaty$l$ ol lunJs by ass•ts Unrewc￿ Re5tsicterf DesKJn8W Total Fixed assets Current assets Current liabilibes 133.519 631261 133.519 720.639 87.428 766.780 87.428 8Y.2J8 6 Transactions with tvllstee's and Mnrcled Durifig the ￿ the￿ ¥¥as no trarwAon5 vnth Tntstees u ¢onntsJ P￿sOr￿ iNAudI￿ r￿￿rat1)n expense6. 7 Twustee Ind•mn Insuranc• During th8 yyar. Insurw¢w3s pwthased to th￿￿ty￿*(Y￿nMit￿ee wnStdÈf￿tt￿ thwr pwt 8 Control The uThJerlhè dlhe Tnèstees.