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|About the CCDC|||6|Structure and governance|36|
|---|---|---|---|---|---|
|We shape the futureofstructural||science|8|Nomination<br>Committee|40|
|What we do||||Audit Committee|40|
|What makes us different?||||Remuneration<br>Committee|40|
|Supporting<br>the community|||10|Risk Committee|40|
|Our strategy: Advancing|structural|||Management<br>and staffing||
|chemistry<br>worldwide|||10|Remuneration<br>Policy|41|
|Our strategic aims, vision, and mission|||11|Risk management|42|
|Our values|||12|Going concern||
|Delivering<br>our vision|||t4|Looking to the future|46|
|Scientific innovation|||19|||
|Impact ofthe CCDC in worldwide<br>research<br>CCDC pubkcations<br>&studentships<br>The?m Crystal Structure<br>Prediction|||19<br>20|Administrative<br>details<br>Auditors,<br>Bank, Solicitors and<br>Investment<br>advisers|52<br>53 )|
|Blind Test|||20|Trustees|53|
|||||Chief Executive Officer|53|
|Key product releases|||22|Company<br>& Charity Registration|53|
|Foundational<br>area|||24|Statement<br>ofTrustees'<br>responsibikties|55|
|Solid form area|||25|||
|CSD-Theory suite<br>Looking forward|||25<br>26|Independent<br>auditors'<br>report|56|
|||||Consolidated<br>statement<br>offinancial||
|||||activities|62|
|Financial review|||28|Chanty balance sheet|64|
|Principle funding|||30|Consolidated<br>statement<br>ofcash flow|66|
|Expenditure|||32|Notes to the financial statements|67|
|Investment<br>policy|||33|||
|Reserves|||34|||











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|Fund|Fund|Fetfonllance|Fetfonllance|Fetfonllance|calellder years|56|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|||||||||2022|2021|2020|2019|2010|
|Ncalo||I|unln|dlr|wurmdfoiCIS|lm|Aol|527|11154|155|1334|108|
|||||||||.4 /0|lu 74|7 II|'le lik|-if4'I|
|C|ss||||||||||||
|P|ffofmanr||flenrlws||k'|||-6 6O|I'I 14|106|1677|-506|



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|Management<br>an|d stalling|||
|---|---|---|---|
|The day to day management|ofthe CCDC isdelegated|bythe Board ofTrustees tothe CEO||
|and operational<br>management<br>issupported<br>bythe ELTand other managers|||who, in 2022,were:|
|3uergen Harter|Chief Executive Officer|||
|Suzanne Ward|Head ofData and Community|||
|Susan Reutzel-Edens|Head ofScience|||
|3onathan Bette|Head ofCommercial|||
|3ames Ellis|Head ofOperations|||
|Bing-Bing Waterman|Head ofFinance|||
|Maggie Brown|Head ofHuman<br>Resources|and Organisational|Design|






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|||||2022||2021|
|---|---|---|---|---|---|---|
|||Note||6||6|
|FIXEDASSETS|||||||
|Tangible assets||12||2,324,407||2,002,697|
|investments||13||6,634,116||7,033,133|
|||||8,868.623||9,035,830|
|CURRENTASSETS|||||||
|Deblofs||14|3.008,821||2,882,309||
|Cash at bank and|in hand||3,634,240||2,613,736||
||||6,643,061||5,496,047||
|Credftors: amounts|falling due wrihin one||||||
|year||15|(5,815,135)||(4,090,917)||
|NET CURRENT ASSETS||||1,027,926||1,405,130|
|TOTAL ASSETS LESSCURRENT|||||||
|LIABILITIES||||9,886,449||10,440,950|
|Creditors<br>amounts|falling due after more||||||
|than one year||16||(191,661)||(226,534)|
|Provisions for liabilities||17||(2,896,332)||(5,197,149)|
|TOTAL NET ASSETS||||6,798,666||5,017,277|
|CHARITY FUNDS|||||||
|Resatctsd funds||10||20,900||39,167|
|Unrestricted<br>funds||19||6,777,865||4,978,110|
|TOTAL FUNDS||||6,798,666||5,017,277|






## 

## 

|CONSOUDATED|STATENIENT OFCABH FLOWS|STATENIENT OFCABH FLOWS|STATENIENT OFCABH FLOWS|||
|---|---|---|---|---|---|
|FOR THE YEAR ENDED $1DECEMBER 2022||||||
|||||2022|2021|
||||Nots|6|6|
|CASH FLOWS FROM OPERATING ACTNlhgs||||||
|Net cash used in opersllng<br>amMNes|||21|044270|tfw.264|
|CASH FLOWS FROEI INVESTING ACTIVITIES||||||
|DMdends, inlsnwa<br>and wnls fwm In os!ments||||(43,776|140,107|
|PUrchsw idtsiiglbls fwsd ssssls||||(4$6,741)|(105,203)|
|Fomign exchange on fixed assam||||||
|NET CABH (USED IN)IPRCVIDED BYINVESTING ACTMTIES||||(202,066)|$ik021|
|CHANGE<br>IN CASH AND CASH EQUIVALENTS|IN THE|YEAR||062400|220476|
|Cash and sash equhelsna<br>atIhe beginning ofme year|||22|341IL2$T|3,100.182|
|CA8H AND CASH EQUIVALENTS ATTHE END OFTHE YEAR|||22|4466JHN|sfS6237|
|The notes on paya 67lo07lorm perl cfthese Nnandal||hdsmenls||||



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|||Ttdal|Total|
|---|---|---|---|
|||lunds|funds|
|||2022|2021|
|||5|2|
|Wages and|salaries|g.1tfdm0|5,448,157|
|Ahendsnae|atsclen85c mee5ngs|216,79S|75,845|
|Lsg8I 8tul other ptofssslottsl fees||4Or328||
|Coltatdlsnta||$2IL545|123,176|
|hlalntsnence|cfsdenMc equipment|$42,1$0|382,115|
|Pnxlucfon|and tfstdbu5on cosh|Tas390|85rstI|
|Mfemnm cn fmelgn exchange||(802N0)|(1,558)|
|Shdt development||43A54|1ABS|
|||72BIL5$5|thgtyA02$|





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|||||Tmsl|Tahd|
|---|---|---|---|---|---|
|||||funds|funds|
|||||2022|2021|
||||||6|
||Bagmats|||708402|897,887|
||Deprealason|||115301|128,434|
||Consultancy|||2S,710|57,001|
||Telephone and network aosts|||14,702|14,$01|
||Rscfulblmnt|||127,707|132,503|
||Legal and osmr paaesdanal<br>fees|||N4S2|110,981|
||AlxN nnd occounmaay|||07410|55,327|
||Banking costs|||$,0ST|5.080|
||Digsmncs on fomlgn wfdmngs|||($11450)|91,720|
||Iluwlance|||87456|52,553|
||Premises ccats|||15IL5N|200,518|
||Ssd dsbl expellee|||2,114|8,963|
||ITequipment<br>software snd hmdwere|||214N|18,721|
||Geneml expenses|||404N|21,054|
||Balfdsvslopolslff|||444N|$5,0N|
||Finance fxwt afunwinding|ofdismwn6ng||Nrst2|14,$46|
||Board meeting casts|||404N||
|||||1437,610|1,848,48$|
|0.|ANALYSI8 OFGRANT8|||||
||||Grants lo|Total|Total|
||||InsBusono|funds|funds|
||||2022|2022|2021|
||||8|E|2|
||Glalffs||0$,48$|$$I403|57440|
||TOTAL 2021||57,040|57,840||



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||The Gmup has made|the fdlowlng|material granb|to kisstusons|duffng the|yean||
|---|---|---|---|---|---|---|---|
|||||||2022|2021|
|||||||6|6|
||NABE OF INSTITUllON|||||||
||Unkmrwly<br>ofLeeds||||||18,0N|
||Unlvmssy at Soulhamplon|||||40400||
||Folyleehnh<br>Unhmn@y|of Turin||||$0410||
||University atShemeld||||||$947$|
||Other immatwlal<br>gmnt costs||||||2,$75|
|||||||70,71S|57440|
||Ogler gnuffs IoIMRINCIIS|||||||
|10.|AUOllORS' RBEUNERAllON|||||||
|||||||N22|2021|
||||||||6|
||Fees payaNS to Ihe CINISYS aulEor kl nmpect af:|||||||
||Audh ofthe Chewy's annual scmwnb|||||$0I4S4|22,87$|
||As texs6on advtsofy servioss not Indudsd shorn|||||$3DT|7,545|
||As IICIHIudlt aefvlcss|nm Inchldsd|sbmm|||043$|eNN|
||STAFFCOSTS, KEYBANAGBSENT PERSONNEL AND TRUSTEBFRBSUNERATION||||||ANO|
|11.|EXPEN8ES|||||||
|||||Gmup|Gnwp|Ctmltty|Chwsy|
||||||2021||2021|
|||||6|2||E|
||Wages and salaries|||IL31IVI1$|4,725,504|&779.606|4,320,718|
||Sodfs seaursy costs|||N2,800|512,005|N$,724|438,181|
||Other pension casts|||901,$22|N0,175|||
||USSpendon pnwhlon|movement|(note 24)<br>(2,$d1420)||3417,340|(2451420)|$,217.340|
|||||4,540,611|9,381,174|3472.284|8,S48,11$|





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||6|
|---|---|
|AtI Jantwly 2022|0,10'7,14$|
|AddEOOS|(2,NOJI17)|
||2JieiL3$2|



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|ANALYSIS OFNETASSETBBEIWEEN FUNDS|-CURRENT YEAR|||
|---|---|---|---|
||Unrssholsd|estrhted|Tohl|
||fttttds|funda|fttttds|
||2022|N22|2022|
||2||2|
|Tanglbh Bxedassets|2,$24,407||2224I407|
|Fhsd asset invashnenls|6,370,627||IL$70,NT|
|Cunsrlt assets|8,804,45$||8,71$,$N|
|Credibxs due wbhln ons year|(5,$23,915)||(IL323,018&|
|ClsfEom due in more than one year|(191,551)||(1012I$1)|
|Plovlshns fofBSO$0les sad charges|(2,098,3$2)||(2,NBB$2)|
|TOTAL|s,srr,sss|20,0oo|B.sss,ah|



|||Unm abided|estrhted|Total|
|---|---|---|---|---|
|||ftfttds|ftfads|futtds|
|||N22|2022|2022|
|Tangible|ibad assets|2,324,407|||
|Rxsd asset investmenls||8,5$4.118||BB3A(ts|
|CunMt assets||8,522,181|20,900|8,$43,001|
|Credbom|due w$hln one year|(5,515,135)||(8,518,135)|
|Credbms|due in more thon one year|(191,551)||((012ISI)|
|pnwlslons|forBebi2lhs and dmrges|(2,8N,332)||(2,NBe332&|
|||s.rrr,sss|20,9oo|s,r00,5ss|



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|||Unresbichd|Reslrhhd|Tolel|
|---|---|---|---|---|
|||funds|ftfnds|funds|
|||2021|2021|2021|
|||2|2|E|
|Tangible|fwed fwsels|2,002,S97||2,002,807|
|Reed asset btvssbllsnls||8,889,844||8,889,844|
|Cturant assabt||5,809,147||5,848,314|
|Creditors|due wr)hln one year|(4,131,853)||(4,131,85$)|
|Creditors|due in mme thon one year|(22S,534)||(22s,s$4&|
|Pnwlslons|foroaMIEss asd chmges|(5,197,149)||(5,197.149)|
|TOTAL||5,128,152|39,167|5,185,319|



|||UnwmNated|estrloted|Total|
|---|---|---|---|---|
|||fttnds|ftfrtds||
|||N21|2021|2021|
||||E||
|Tangible|fixsd assam|2,002,897||QN2,NT|
|Fhed asset invasOnenls||7,N3,133||T,N$,1$$|
|Current asseh||5,456,5N|30.1sT|Srgss,OSr|
|Credbms|due within one year|(4,090.017)||(4,N0,017)|
|Credsors|due In more than one year|(228,534)||(226,N4)|
|pmvlsions|forlmb5Ees and charges|(5,107.140)||(6,107.140)|
|||Sara Ilo|301sr|sdylr~|





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