Year ended 31 t.larch 2021 $8d lact thatyw Ire more IlkelytO9d can￿r and dlt from It In Yorkshire than ItyOLI Ilve In othei p3rt$ of En9L3nd. The reastsns are many and varied. InclwJlng pjverly, lack of aeeèss tr> health sèrvltes and exposure to rlsk factors such a5 smoking or harmful substances Tn thÉ environment or workpFace. It Is also a tuEt Ih¥l mony pÈoH¢ in ttur reglon go to thelr doctor wlth symptoms Liier and are di4fitssed when thelr cancer is mr¢ advanced. Wt are ¢unmltied tochan9in9 thls-to savin9 lives In Yorkshlre. afid lale5t work Is detalled withln this Report and Consolidated FinEnciEI Stttemertts. NO￿ of thls Ilfe-5aviry wixk WfAJld be Possib￿ wlthout the ppori of don¢xs, volunteers and- Most importantly- tho help of people affected by cancer. 2 yorksliiiec(*iicei'resec£rch.oig.uk shire live PATRON OF THE CHARITY REGISTERED OFFICE J8coE) Smlth House 7 Grove P8rK C(yJit Hlrrogaie HGI 4DP REGISTERED CHARITY NiJMBER 516698 (England and W&les1 REGISTERED COMPANY NUMBER 1919823 Slr Mlthaèl Porklmn CBE BOARD OF TRUSTEES MrGraham BervSlk 8Sc IHon$l ICh8lr} Mrs S•ndro Dodson OA (Hortsl (Deputy Ch&lrl Mrs Mwgaret Klt¢hlng RGN, SCM, DN, DIP Dgrtnattsbgy, MMEd Scl Iretlr¢d 31 March 20211 BANKÉRS uoy&5 T98 8ank He 617 P&rk Row Leed5 LSI INX Yvelle Oade 8Sc (Honsl, MBchB, FRCPCH Mrs Cattr*rln¢ Ru5tomll LL6 (Europe), LPC (r￿gned 141101211 Mr epbby NdawuL• Bsc IHon$l, FCA M5 Liz Rlch8rd$ 8A (Honsl. ACA SOLICITORS The Charlty et)gagesthe nwst Bpprosylate 5ollcltors for the glven elrcun)stance does not ret81n 8 dedlcaled P18Ctke M$ Ro$*mÈryCook CBE. HonDLltt, Msc, PGOip. RGN, FQNI. FRSA Mr Chrls SIBtÈr ￿£1P5 AUDITORS Mrs aarè Flèld MA IHonsl Oxon Mazgrs LLP Sth Floor 3 IW*lllngton Place Leeds LSL4AP Dr Paul R5¢e BA (Jolnt Honsl, Msc, Pho, FBCS (app¢5nted 23rdJuly 20201 Mrcralg Bomar MA Hons (Ecwl lappointéd l Jan 20211 EXECUTIVE TEAM Dr Kathryn scott Bsc, Pho Ch5ef Executive INVESTMENT MANAGERS IiterChevk)t Urrdted 4th Flooi., Trie Pliin8de 73 Xlng Street MaK￿$ter M2 4NG klrs JulietGlendlnnlng BA {Honsl, DIP Director of Brand and Relationshlp5 fvlrs Joanne A4c>rnln eA (Honsl, ACA DirtctOT of Tinbnte and Corporate Servlce5 Srnlth & Wllll)mson INestment Management LLP 25 Moorgete Lond¢)n Dr Stuart Griffiihs Bsc. PhD DFrector of Research ènd Serv5ces IArfimtrthy Willlams LL8 (Hon5). LLM Company ￿cretary EC2R 6AY 4 yoi'kshirecaiicerresectich.oig.uk CONTENTS Ihtroduetlon - Glvlng Yorkshlre More Llfe to Uve . Me55age from our Chalr Chief Executive's Statement Trustees and Strateglc Report How we help Flndlng Ways To Prevent, Dlagnose and Treat Cancer . Action to Prevent Cancer . Action to Diagnose Cancer Actlon to Treat Cancer Ploneering Research 2019 Fund:.ng round - clinical tria s Cancer and COVID-19 Worklng in Partnershlp7 . Leeds Uyited Gibe l= Some Welly teicome to Yorkshire Maklng a Difference Supporte's and Volunteers" L¢cal Volunteer Groups General Financlal Review and Principal Sources of Fundlng Independent Auditor's Report Consolidated Financial Statements Our Chalr, Graham Bervllle, records his thanks to everyone who has come together to save lives from cancer in Yorkshlre during a year whlch has impacted everyone and leaves a cancer legacy whlch means the Charity's role Is more vital than ever. with a strong, tong-e$tabllsh¢d herltaga, It ￿11 take mtsre than a ￿￿eMIe 1oblow thlg charlty Qff course. York5hiTe CarKer Reseorth storted out h 1925 85 the Yorf<$hlr ncll of the erft15h Ernplr¢ CaKerCoTry)algn- a ￿ete9$f and ptyNerf￿ grant-glvlry b￿ywh1¢h fur￿ed ￿rtant s¢kntifKro5e8r£h into 4nd woneervig new troatmonts, TtscharSty ha5 r*ver wav¢rwJ fromlN58rybltlon. eul It15 und*nl*bl¢ that. across thè tountfyl COVIO.1g ha$ hgd a devostotlng effo¢1 upon cancer servlces. delwlng dlagn0515 and tr£Btr￿nl. Thls ha$ had a huge Impact on the Ilves of those wlth canrqr ind those fove and eart for Ihom. Wo ar¢ worltlry toon5uro th5$ Imp8¢t Is rK)t a la5tlng one. In4f*d. whlht s￿e of our work to sa* 20C￿ more M¥es a y¢arwas tempor£rlSy paused whll$t htsspltals tackled COVID-19, we wgrk¢¢ to get the resewch we fund back on track as 4ulckly as posslkle. whl&t 8tways 8Llhei51i9 to the latest ￿fEty guklanc*. 7hg wllllngne55 of partitlpant$, supporters and volunteers to ¢ontlnufr to contrlbute In *ny wayppssible In an extrtm•ly chall•ngli)g ¢nvlronment ha5 been humbllro. Wt have funded £10.9 mlllk)n Iii research In the 2020121 %ln•iid41 yaar. Thls Includes the CovidSurg.Cancer research, bvhl¢h Investlg8ted the effects ol the pai*emlc on cancer treatTn8nt, and è remote stop %noklng servlce wlth research taklng place In a vlrtual, rathèr than In- person. settlng. We have conllnued towotk tOW8rds our $trateglc oblectlves, awardlng £8.3 mllllonfor ploneerin9 nèw research prcllectsthatwill In￿￿e more than 9000 pe¢)pl(t. These Incknde wolects for c3neer s¢reenlDg, stop smoklng support and Iinprovlng treatments like radloiherapy. We are 8150 brlngln9 more cllnical t¥laLs to Yorkshlre whlch rn¢an5 that people in our re9iw Can be 8mong the fI15t loreceive access to ploneerln9 treat￿nIS and Innovatfve tryays to diagnose ¢#ncer. Looh'no to the future we have alreadycommhted fundlng of £47.9m to a wlde range of iesearcli proJecl&Qesl(Jne(t lo deliver our keystrategi¢ objectEve of delfverlng 2Crf]Q fewer deaths from corKer In yolkshi￿ by 2025. Ourwld standard peer revléw protess, In Ilne wlth Ihe st&ndards set tythe A550ciation ol Medl¢al Researc Chfviltles, enwres each appllcatlon Is té$ted Lvlth b•nefi¢iarfes as well as expert5 from around th¢ workl. Striteglc allgninent 811LS excellence are Iwo *s$ontlJl qualitle5 of all successful oppl1catl0i￿ as wo seek to fund research th*t save$ Ilves In Yorkshlre. As part of our Strategic alm tts ¢roale 8 stronu brand that Is regIonal￿ known. trusted and supported. the Chai5ty has t¢nipkted a brand relresh. Our alm is toJpp•8r distinct froni tsthèr can¢or at)d rogEonal char5tle5. It 15 our hopt Ihat thé Amual Report Sn thls new format wlll be morn accessible, rèath a wlder audience and explaln wlth greaier cl8rlty tlie many w&ys Iii syhlch we are glvlng Yorkshlre r7K)rtr Ille to I￿e. It Is thanks to tlw extiaordlnary people who 5upptrrt Yorkshlre Cancer Research- th8donor5, functralsers and vtslwteeis- that our amazl#o rese8rchers contlnuousty plon••i, In1)￿48te and Improve ca#ctr d￿1110$￿ •nd treatment. Llke mèny other chèrltlts. 0￿r the 2020121 yo 55gnificant tiumbÈr of our fundraising activities wiere cancelled and thk8 lryjacted Intomè. Howwer. re5er¥e5 ate Strong, )nd weare extrèmely well placed to contlnuetDdellver 89aifist ourg081 of acllevlng 2000 fewfjr car￿er deathseach year Yorkshlre. The pandèmk has provlded additlonal challenges In our efforts to prÉvwt, diagnose and troat cancer. wlll bo takln9 time to rwièw our current strategy and pricyltles In I￿hl ol ihls. But wlth the1mPaCtof delays In cancor servlces b￿(￿rIng Increa55ngly apparenL We ¥¢ more commltted than ever tosavlng Ilves thr¢yJgh cancer research. Thank you for mak5ng thlg PK>sslble, On tr￿￿21f of the Board our ho4itfvit thanks tts *1 of Qui sUPP¢rt¢rs, dowrs, local volunteer 9roup mÈmbers and r&ea¥cners for ènat>llt)g us to contlnuelo address the c8ncei Inequaiityes lrt YoikShlr¢. MrGra￿￿￿ Bwwll1É-Ch￿r 6 yorksliir£cc:m9kn"pg• (i .Yoikshlre has ih8 tr.rJ est 5ty.ok:-ng ?tes ir.England. l%'e e5tlmè:e.th*.VcFks.: ..1 n'.ss:heC*sernm¥.tSsm.?j(e- Yree soclÈty ta'get ￿. 15years. Hdp-.MpEGpequit￿.a￿l￿5 fa-. cho(i hes tiierèfore .boc.)mea fx'J5 Tcr.YoIkshireCa*￿rRÈStsarEh oa srr.0ke"£an￿..Dr:hP."l.heaII) It?% . imLXirtar. 10Fr￿l-È.0Dl"0nSfQrF￿P..e Y.'h>cP,-ose to .qJit srr.gliing ar￿..￿￿. 1> ¢..￿.￿£a-.e! r.l.:nc a%arlelj-. pioJr8rrimES t￿0￿9.. Ycrksnir.e. Action to prevent cancer South Yorkshlre and Bassetlaw QUIT Programme The QUIT Progfamme is Thls groundbreaklng programme Is bélng dellvered bySoLrth Yorkshlre a new Inltlatlve whlch will and 8assotlaw Integrated Care System In partnershlp wlth Yoykshire transform the way tobacco Cancer Rese)reh, Iwe local authtslltlés and local Stop Smoking 5erthtes. It has the Pole￿al to save upio 2000 Ilves and 4000 hosplt81 re" addlctlon Is tackled in our admlsslons a 54ar. Thls IntèNentk)n Isvltsl tothe health ol people In h05Pltals, offerlng patients thls locallty, whère nearfy 200 000 peop￿ smke. who smoke access to effectlve York6h5re Cancer Research Is provldlng £1.8 mllllon to lund 45 spècl8llSt treatments and support as tobèeco treatment aotrlsors, reachlw every hosplt81 patlÈnt In S￿￿th part of thelr routlne care. YoTk5h1re aiid B8SSQt1aw￿th th• support thèy rteÈd to stop smokln9 for9ood. Thls wlll redu￿ the tlsk of prernaturè dÈath fKom a wlde fange of smDklro-r¢lai•d cancers ènd save many famlllei trorn the devBstaii¢n that coneer brfnp. 17 Action to prevent cancer On National No Smoklng Day in March 2021, "After a year of stopping Yorkshlre Cancer Research launched an investigatlve fllm that tackles the myths and smoklng, I felt better in misconceptlons surrounding vaping, Through myself. I dldn't feel out research and Intervlews wlth experts, the fllm of breath all the tlme explores the truth about vaping and addresses ljust felt alive." the confusion leadlng to the bellef that vaping Is as harmful as tobacco. Vaplng Demystlfled has now been viewed more than 377 000 tlmes, provldlng smokers with the Informatlon needed to make an Informed decislon about uslng vape products. Mike, who used vape products to stop smoking. 377 000 18 yorkslilJoLrJnoi'i?Èeoitli.oJg.uk Action'to." Yorkshire Stop Smoklng Study Working glongslde the multl-mllllon.pound Leeds Lung.H¢alth ¢he¢k, the Yorkshlre Stop Smoklng Study tests whether people can be encouraged to stop smoklng by glvlng them plctures from thelr own lung scans, showlng posslble lung and heart damage. As par.t of the study, up to 12 weeks of stop smoklng support Is offered to all people attendlng a scan who currently smoke. Those who choose to take up the offer can.see a sp.ecla115t advlsor straight alway vohlle at the moblle unlt. Informatloi Is also provlded about hoiv 5topplng smoking reduces the rlsk of cancer and heart attacks. DLrin J 2020...%hen access to In-Fersop. stop 5m¢klrg se. viCQS rostrlc:ed. YorKsh5re Can-er Research fundgc a rÈm.)te stoo SmOki*g seivlce F lot. There $re rno"e ae4ells or.ne Success tr Ih&S Plo: n otrr Cancer & COklD-*9 5e=rion." "Havlng the support of a counsellor was fantastlc. She was always getting in touch aslung how I was doing. glving me encouragement and supporting me. I felt I wasn't dolng It alone. When it comes . to Yorkshlre Cancer . Research it's because of their initial idea and thelr commltment Im sat . here In my home healthy. . full of motivation and confidence I can t thank them enough." ."Fiir.Liefii?y.": . Geoy. Ycrkshlre Stop Sinokiog Study participant. toprevent and The work of Cancer Wlse Leeds has contlnued through 2020121. ThSs programme, dellvered in partnershlp wlth Leeds Cancer Progiamme and working wlth a network of GP practices, alms to signif icantly Improve bowel, breast and cervlcal cancer screenSng rates across all Leeds communltles and to raise awareness of cancer sign5, symptoms and risk factors. Durlrtg tho pandemlG ￿rtIcIpat￿n In cèrvkal screening derjined. In Leed$, •round 6,500 fewer women Y4èr8 screen*d between February 2020 at)d February 2021. Measures have been taken to address the con¢ein$ of women about the safety and hcc*$$lblllty of atttndlnp 5creenlng appdntments, Indu￿rt9 pK*uctlon of p Sele Screenlng for Cervlcal Cancer vldeo and Improved av811abllity of weèksnrl appc¥nlm¥nt$. . J imensions 20 yorkshjrecancer￿5eUrCh,0rg,Uk Naggina s story diagnose i) cancer -Ftnding-cancÉr- early when it's easier to treat. diagnosed later than elsewhere in England.-4 In l-o cancers are diagnosed atstage 4 ivhlch. Is the late)t stageth3t cancer can be- diagnosed. .CarKèrirrwctspoq):efTm &..b8t￿Gun0safjdh*7k5 cf i*. FaC￿r5s0¢h0sr.IailyJ￿.10n. ru￿.-..Y èit **h9V.tyi￿ 5uch85%nok'.n.* aro all rea>Ong"JryytknVdY - ￿1mpa￿l bpbeiJeiOP ng. Ouralm.'sth31 - ".ii¢very ¢fsutie¢sfi( Ire8ttrie￿. 22 yorkshirecanc¢rresearch.org.uk Actlon to diagnose cancer Rèsearchei: Piofessor Mat Callister, Resplratory Consultant at the Leeds Teachlng Hospltals NHS Trust and Project Lead The Leeds Lung Health Check Is a major charity research project, an £8 mllllon Investment in a moblle screening unit whlch travels the clty provldlng convenlent lung check-ups for local residents, Smokers and former smokers are Invited for chest scans, prlmarlly looking for slgns of early stage lung cancer, but also dlscoverlng other cancers such as breast, kldney and oesophageal. 8ecause these Cancers are c8ught earller would ot￿rwIse be the ca5e- often before any symptoms are experlenod- the Ilkellhocd gf suc¢¢ssful trwiment and ieEovery ts gre￿IlY Incrgbsed, The wolect bas helpe InspIrear￿ Inform the NHS to a£70 m1111on Invt5tM¢nt In 10 addltlonal moblle Xannlng unlt$ across Engl&nd, thréè of which wlll be In Yorkshlre, bringing the bènef5t$ of lu screenlng to peopk In Hull, Doncaster and Klthlè¢$. Frorn June 2021, ind5vldu•l$ retwnlng tor thelr secon¢J lung xan wlll bt oflwed the opttonof extendlng the Scan t¢ IhE Igwpr abdornlnal reglon ¢0 ¢tsd< for WdrRy ¢anEer. rh15 additlonal rese&rch project, a wortl-lir$t. Is led by Grant Stewart, Profe559r of SurglcalOncol¢9y atthe Unlversltyot Cambridge. ac) fundlng gv•r7 y¢ar$ t¢l¢ph0Th• 4$1¢$$ments p¢9p195¢reon￿ on th• mobl1* unlt Mor¢ th&n 150 ¢#n¢qr$ dl*gn088d, mo$t •t grb oarly8tagB ,. ipetty Lung people have seen B stop smokltkg speclallst on the mobfle unlt 23 Lynne's story iasAvi)rptbèt4hQ%V#S'.pi rlsk','.4t',her-xbn,:..Lyi￿e:1MrnQ￿bt¢ly.:1Dts.';ot-., PrtsYesw.r.Rp¢.tioi.'M.y.tiay,pt.,t.4>...ynly4ril'iy.;of.,N'ittlti4bw.Tfy:":li:4lSC$'.fv￿￿1d.-.' . .,¥y.YK)rkshlre QhCtY.fpRpitb,." itr1.o.'Wp¢.ks•fto.i:b'èf..$¢aii,'.￿n0 fKolvid'•Trbgn8¢011.aikjn'oi5er"tb':- •ttsDd,in'a'pii&!rfih)¢rf'i￿lth.,P1.Qrl8gor¢9'lllst¢r,'1i4h1r8.sti1",W9$t0￿..;',- Fhg.hpd.lyng'cah¢ir.'"L¥￿'D.a b.ocl".gnpppratlon t.o h￿e.port.()Y..fv'Pr.Il)n1.. Inlti.htsT'.i¥:inkh'npdig: D.p.'f.urthertrAatiiK9hl ivas r¢AulreLI,'5he46iio%v',: lJllJyr¢'wv4rg¥in¢.:'lri, ggg1.¢.'h,p8jth',': 4¥sdtie¢. , ttylife: 24:"".yorkshlr¢canurresearclLofg.uk".- Action.to'.;': diagnose cancer Findlng cancer early wh its ea￿er to treat. Action to ,4 dlagnose cancer Researcher: Dr Christina Dobson, Research A5soclate at Newcastle Unlver51ty More than 850/0 of Yorkshire is rural and some of these areas have slgnlficantly higher rates of cancer when compared to England. Rural populatlons in the UK often have hlgher incidence of certaln cancers and fewer cancers dlagnosed at an early Stage when they are often easler to treat. Yorkshire Cancer Research Is funding the RURALLY study, explorlng how people Ilvlng In rural Yorkshlre experience and respond to bowel symptoms. The stuéy Is uslng Intervlews a¢ms5 four rur•l CYP pr8Ctlrèg tts flncs thlt about peop*'sexperl?nces and tht reasons why they dld. oi dld rnot, goltssoe a GP. The 8im Is tor local communit4¢$ to help ￿￿eloP an Intervèntion that encourage5 people to seek hèlp early far passlble cancér Symptoms, The pèndemlc hbs hlohllghte.d the i￿gertt nèed lor peopleio contact thelr GP w51h posilbte syihptoms ¢1 cancer. An England.wlde studylrom tht Uhlvtrsityof Oxford, ot whl£h Yorkshire Cancer Rèsearth was a pari, ShO￿d that bÈtwÉen Aprll and Oetober 2020, 550 few•r p￿pIe th8n expocted wèré dlègnosed wlth *)owèl t3n¢er In Ytykshlte. RURALLY Itself wassu5pendod for three monllis over the summèr of 2020 ¢Sue to the p8ndemlc. Up)n restaltlng the study¥ the Charlly h85 awarded 8n extra £10 OOGto RURALLY to allow Informatlon on understandln9 the barders to help.$eek5hg behavlours, beth pre- and post-pandemlt, to bt gathered alongslde the orl9ln81 objectivès of the study. 26 yorksliiiecanceiresearch.oig.ul( Awareness and Beliefs About Cancer- ABACUS Pr.-Kate Brolp,:'.,¢8r;¥,IV",Lln)*erslty,;': g,:),., completed In De¢émhèr'3q29,. The.A8ACgs resear¢h proJ¢¢:t,usq¢ a brlpf,, ,.. ::,, ,.touclis¢reeri questloDnaire *o.'Hsk rrierribers p,f ,the publlc aged;over;4D,lo towny:, and ¢itl¢s In¢iudlng,Doricaster ,F4rnsley, Rotherhpm,,Sheffièld and.W9kef,leld.; ,'tr,Apnll)Fe'4 Fe,Wlt94n&bgliAylour ¢)JrFèadvl¢¢,:dpjlypr*ti14iin pasy_;' '1¥ori thonitiel,Sv•r44 ty Irilnodlaj" ,dvlwrs.'ovhr,o p¢rlèd*fil%monlh% ..14w¢-',ii!e fqso4rniTh$i r4￿MPlom9 •nl sgld thtyWould,Fq#*.¢o¢torfoongr Ilihgy, .. ?'1 Il'a'$lmpl¢ woytyilmprov¢tty4 p4tly,¢pteciityn,oY¢qDotj$ria111ry9,_y,or*,.; . parilclpa.nts_ --corrimuiiitie3. . . Action i to treat cancer Improving cancer--"';":':;" Actlon to treatcancer Researchei: Professor Phlllp Qulrl Unlversity of Leeds More than 1300 people dle from bowel cancer in Yorkshire every year. We are commltted to reducing this figure by implementing a gold standard of bowel cancer care, which is accesslble regardless of where treatment Is recelved In the region. In March 2021, the Charity announced a further £2.Im of funding for the Bowel Cancer Improvement Programme over the next five years. Work cÈrrled out ￿rtce the pragramme b8g•n Sn 2016 ha$ 4lre** Improved the p￿CeSseS that cllnlclans acrc65 Yoikshlre usè te tré81 pètlènts In 8reÈ$ suth 8$ advanc￿ dlsta$e and radiotherapy. The te8m h85 8190 Improved the chen{#n kadto bertersurgery. reduce CcM￿￿8￿on5 and Irry)rove Su￿￿￿1 r)tes.Thl$trfal whIteStwhetr￿r fvrther benENtscan be madety9lvlngflt P41fentsmor8 Intsnswe ctrEmot￿r9jYondpI5O testcttffer¢nt WOy5 of treatlryfsderand frgm patlent$ ￿th ch¢mothorapyèh88dof Surgery. Dltsn Morton Pmfessorol ￿1r9ery tthe iknlv¢rsltyof Blmlnghllm J*MySg119miT Censultant Medlt&l or￿oI0915t 8tlhe Unlv¢isltyol Le￿5 FINESSE R•sÈarch•rs: Uslig 8n exbthg rnedlc*tl¢n that￿Owspr05t2te ￿￿￿th, Fln&t*idè, tNstrLg1 WKI test whetherth8 m￿1(¥*￿)nc￿ ref*jCetr￿r￿d for •xier6he surgeryor radlotherapy in men wlth @8ty Stage proststecancw. The 5ix*ear wlll1iw￿0 SS) men InYorf(shlre., Jgm¢sC¥tto. Proféss•rolUroW at the Universityof Sh•lli¢ P¢terS451Tnl Piofessor of Can￿r p￿entIDn ai Kh9'$ Cdlege LO￿On YORKSURE A*corKltrLql by Profe5y)i$Catloand S*r vwlll wessard comparetheu5eof urfnesdf-te$tirYJ klts pmdcommunlly eatydetecbon dhkslndl8gn0￿rv peoF4Eat lilghrllA (rfdwgloplng ts1edderc￿&r.ThIs1rI81, InVo￿lI)g 6(X)OpeOp￿.￿ll assessthe [X%￿b￿￿Of èn eailydetection wojramme éor L40(klerfxncer InYorksNrt wheresuthval rats$8re blwerthanthe nbtiorN*l Bvwage. 34 yofv'ksliiiEcancei'iEsearcli.oio.uk Yorkshire clinicaltrlals At Yorkshlre Cancer Research our alm L% that evwy year at least 2000 more pÈcple survive cancer In ￿r Teglon. Each yearwe fund EIO million of v**al cancerre5earch and it's all for the benefit of pe¢pb l) Yorkshlre. E-cigarettes for Smoklng Cessatlon And reduction In People wlth mEntal Illness (ESCAPE) R¢s&archers', Elena Rats£h8n A$sodate Prolemr In Hè8llh S¢S¢no5 at tt)è Unlvèisltyof York Peoplewfth rwdntal It￿th cO￿EtIOnS￿re dWroFOrt1r￿￿te￿affected bysmoking and despltea St￿gdeStre toquit,olten lind iti*ftieulito $0. 7hl$trlal wlllalmtoeststllsh whether an offerof vaplng pre(IL ran help peopl¥￿1th mental Illness qult $rrKJkkng.fhe￿ear¢herS￿jI wL)rkwlth mental healthtruststotest wh8th8r Integr8llng the offer of vaplngstarterklt helFS Inc￿50 thenunb8rwlKJquitsueCessful￿. stlng hdrff•r*nt way5tosupp)rt smokers toqult for gOLxI, we e*e ccynmltted tohelplng peO￿e across Yorkshtre hJvè agreater Ilkelhwdof a thger, he81thler, Ca￿er-free Ilfe. Llohshh Prof@ss¢y In H*8Kh Psychology at UnTVer￿1Y Cdkg8 London AURORA - AGUIX Enl￿nCed Radlotherapy for Rectal CAncer Resèar¢h•r, Agron Quyn Assoclate CllnF¢al Professor of Surg•ry at tht niversrtyof Lee45 Th15 trlal w411 test wh•ther radloth•r¥py QAn ts* made YrDre effect￿ for peoplé wlth some types of advanc¢d bo￿21 •nctr. The re5eoYch wlll fit)d out if new technolow can be use¢J to Increasè the d8mage d)neto can¢¢r ¢ell$ by radlothérapy and reduce th¢ ne￿ ft)r exten51v surgery. whlcl) can have 51gnlflcdnt 5Ide etlects. If $Lrce$sful, a lar9erx#le study could follow. Cancer Paln.assessment Toolklt ftir Use In RoutlnE oncology outpatient servlces (CAPTURE) Research8r'. Motthew Mulv•y Sénior ResE¥ch Fellow in P•lliaUv re Jt the Universl£y of LeÉ*1s Yhls *rlal wlll Inve5tig8tE whether an ex15tlTh3 Pain a55e55ment tw1 can be successful￿ adapted and Introdu￿ into oncolo9y Otstpètient servaces atresg Yorkshlre. Thetrial could lèad to improvéd pain m8nagemEnt for patients in the regbn. 3$ As we emerge from the restrictions on our lives caused by the COVID-19 pandemic, it's an opportunlty to reflect not only on what's happened, but on what should happen next, COVID-19 has hlghlighted problems that exlsted within cancer services long before the pandemic, wh5ch Yor1tÈctstaff and membèrs of the public attending selfrreported quit rètE of 58%1oT NHS $top$rTh)klng servi s¢reenir£ And to malntsln soc181 distsncing. NumbErs In En9lÈnd between April andJune 2020. ThE5U￿SS tsf thi5 atte￿Ing iemained at pre-pandpmic levels with lung and study h8s led Yoykshlre C8ncer Researth to ex￿0￿ optiun5 other cancers be5ng detectecl, with the rnajority found for developing a lon9W-term remole stopsnN*in9 ser￿ce at an earlystage when Irealmenl 15 mosl likety to bÈ with the Yorkshire StopSmokirwJ Sludy team. effe¢tlve. 38 yoi'kslili-ocuiiceri'eseairli,t)iy.uI< Cancer and covid COVIDSurg-Canc*r Internatlonal Rese4rch The coronavlrus pandÈmlt has had a devastatlng Impa¢t on the treatment of eancer worldwkle. Yorkshlre Cancer Research has supported a ok)bai sludy INestlgatlng the Impactof COVID.19 on thè carè of Ca￿Cer patlents needln9 lff¢-swlng surgery. The COVIOSurg evaluatlon study ex8mlnpd data Involvlng 9171 patlènts In 55 countrles 8nd merj to holp answèr questlons about how hospitsis were mana9ln9 surgoryduflng thé pandèmlc and monltor the efl¢ct on PBtl8nt5. Our fundlng he￿ed coordln8te the Invplvpment of ho5￿tal$ InYork6hlre and anal￿e the dats collected. Access to GP Servlces The pandemlc haseaused a huge barklog aEfoss 811 bealth $erwl¢e5 that must be urg$fttly $ddressefl. Bet¥veeh Aprll and Oècèmber 2020, It's estlmated that more ihah 3500 peoplÈ lrt Yorkshlre were not dlggnose¢ Itll cancer should havè bèèn. any ¢1 thes? people w511 be lfvlng wlth canc$r rlght now wlthout knowlng It and may have thelr canterdlagnosed tel than It Should have bqpn, The wor5t.tasè scenarfo Is that all these people are dlaBnD5Bd wlthcancer onlyonc8 It bÈcomÈs an emBrgpn¢y, rBthe¥ thén earller thrO￿h 5creenlng or aWa￿ne* of symptoms wNch otball Club Offlclal Cha¢lty Partner In September 2020, York5hlre Cancer Research was announced as the official charlty partner of Leeds Unlted Football Club for the 2020121 season. This Iconlc football club, 50 closely tled to the identity of Yorkshlre, has been promoted to the Premler League and Is the centre of considerable media and commerclal interest. Together, we are using this status to ralse awareness of cancer and the world~leadlng cancer research taking place across the region. As part gl thg Club'$ Invofvoment wlth us, the home of Leeds UnltEd, £118nd Road, was Ilt up In thecolDurrd of Yorkghlre Cancer Research to marl< World C8ncer Day on alh February 2021. The first-tegin players wore York5hir¢ Cancer Research t.shlrts for the warm.up durlw thfylr flxture again$¢ Everton on February 3 and took part in filmln9 ¥tsout World C8ncer Dby. oswell &5 promotlng Iht Charftyon thdr cSal ¢hsnnBI5. "As a club we commltted to the local community and if we can help to raise awareness among our supporter base and savejust one Ilfe then tlv's collaboration wlll have made a Iwge dlfference," Paul Bell, Executlve Director, Leeds Unltsd 42 yol'kshlreconc¢ries4oirli.oig.Lik Leeds legend Dominic Matteo's story Working in partrtershlp Yorkshlre Day on 1st Augijst Thé Gfva It Strm¢ Welly campalgn went atread wlth $pmg 5nnovatlve Is a great opportunity to change5. YoTk5hlre CBncer Research entered tho wtsrld record books for the most vlde05 Upload￿ In one hour on Fo¢¢book of people ralse awareness of the throwlng & welllngton boDt. After enrour?glng pgvpl* 4¢r¢)$s th¢ activity that is taking place to reglon to take PBrt In the'world'5 blgge5t vlrlu41 welly y¥on9', 255 prevent, dlagnose and treat people dld It In Bn houf. PartlclpantS WEf¢ 85kpd to mak¢ a donatlon cancer here In the reglon. In for every welty thgy wanged to help the Charlly ralse lunds so thal more people In York5hlre con'glv¢ un¢¢r the boDt' for good. 2020, our supporters were incredibly creatlve in flndlng new ways to raise funds whlle observlng soclal distancing. 44 yoI'kshii*caipcÈri'eseoirli.oiy.Lik Fiona's story Working in partnerships In March 2021 Yorkshlre Cancer Research was announced as the officlal charity partner of Welcome to York5hlre, the organisation that promotes the region as a destinatlon to a global audlence. The partnership alm5 to ampllfy awareness of the Charlty's ploneerlng research throughout Yorkshlre, from big cities to small rural communltles. Promotlon of the Charity through Welcome to Yorkshlre's internationally recognlsed events and vast online output will wlden recognltion of our work. The benefits to boih phygicol ind mental h¢a1thof exercise are now well.estab1ls￿td, 5n¢ludin9 reducing the rlsk ol dÈveloplrvJ wme cancers and Contributing towerds è full re¢overy ￿ter eaneertreatment. Tho Ttyjr de Walk5hire tampalgn p3rtnershlp betwèen the orga￿$¥lIC￿s, taklng place lrt 2021, wi11 comblne thÈ stumlrg Yorkghlrtr landscape wlth L￿r mIS￿0Th tohove ljggest Impart on cancerfor people In Yorkshlre. 46 yoikshlrecaiiceriysoaicli.org.iik Yorkshlre Cancer Research is commltted to making a real and positive difference to the lives of people in Yorkshire, We are taking direct action to prevent, diagnose and treat cancer. This is only Possible through the commitment of supporters, the willingness of volunteers, the decllcation of researchers and our detailed knowledge of the causes and incidence of can￿r across our reglon. .18 1'01rf5hire-GIiCc*rJeseai￿1l.0lg.Li.x Illl'llli The dlfference is you Thls year has been extremely challenging for fundralslng. Events have been cancelled and opportunltles to ra15e awareness of the Charlty have been Ilmlted, impactlng on our ablllty to attract new regular donors, Despite these challenges, we contlnue to be Insplred by and thankful for the support of people across Yorkshire wlthout whom more people would get cancer. A$ a r*sult of fvndlng cancer rèse&r£h projects to Y¢rk$hlre, 300 000 people a¥e n¢)w Ihvolved In studle$ and servlce$ funded by thecharlly. Tttls régèarth Is h8vlng ¥n Impact on th8 reglon and, coupled wSth cur Investment In publlc erqagtm*nt, we 8r* In¢reJslngly pooplg Involvgd In•*udlo1 and i•rvlc4gfunded byth• Chailty re&1 dlftsrence to Ilve5 In York5hlre. Thls provlde$ 8 grwl stlmulus to our lundralslng 8ctlwly and conlflbules lo tlie qff¢)rts of our long-term 9JpPOit￿ who have contlnued to fundrolse In Inn¢vatlve ways thr¢u9hout Ihe pandemlc. vpluntoers h•vp lolnedthq r•t•ll téam thls y4•r lo¢al volunteer groups ècross Y¥rk$hSr* Ir￿oMe rrom $t4PPOrtér ¥lft$ & fundralslng SO york5hiietanceritsearcli.oi£t.ul¢ Catherine's story The difference is you As soon as the Government announced that, along with other hlgh street stores, our shops have to close, we swltched entirely to onllne trading. Onllne sales were the equivalent to those rnade In shops and enabled us to contlnue to fundralse through the sale of donated goods tl)roughout the year. Our reiall actlvltles 8re rellamt on voluntèers and Ihls thc>S4 yyllh mort tlme than they would usually have has boen esp¢¢l8lly true wlth the enllne shops. Ev•iy because other activlties heve been on holrJ. What dortèted Item. from vlntage tashltsn to vlnyl records thèy 811 have In common Is a wlllln9ne$s to share Ihelr to Ilgsaws ltsy far our bl99e$t seller durlng lockdown) Ilrne, skS11$ and Ilfe èxperlence ènd they play A viial has to be eoiiedèd. sorted, IlstÈd and dè$p8tehed. le In lunrtln9 life.changlno reseèreh 5fi Yorkshlre. Over 60 voluntèèrs have lolned the team thls yeaT, Our volunteérs comè from all walks Ot IlfQ,' li) the pasi year kve liave been lolnod by those oli fvrlough aiid 52 yoI"kshirocuiicori'es¢uicl?.org.uk The difference Is YOU The backbone of our fundralslng for so long, mary of our Local Volunteer Groups have been In exlstence for over 60 years- our longest standing group Is Great Ayton, formed back in 1948. There are 27 groups In total, and In a normal year, there would have been numerous fundrals5ng events and activitie5 afternoon teas, fashion shows, lunches wlth guest speakers and quiz nights. Sadly.thepanrlemk hashad a hugè knpatt ontheab511tyof tl*sogreups tomÈell￿¥the[dnIj ttsfuFIUldiS*. Ivslilili¥i)b iiipbi*duiil)9 tlw ptsrylemlc moantthe maJorItyc￿jwrfl holl treeveiitstheyhad ￿a1)n¢￿. Wé mTssod thelrsupprtand thdr presence In our bc8leommunltlès. Son*gioJpshwe c￿tin￿d10fUndra1sew￿re po5511￿8, wlth Leeds and HLiddwsfleldb•ng P¥tICu￿rIy ￿n￿ltS¥e, sfjllliig f&£ coverln9s, or9anlglnq a reclpebookand hddlng vlrtual even￿ We know that al the gr￿p* Ilke u5.cannotwalt tohokl In PerX￿ eventsagln. of fundrglslng by LKo1 Volynteor Groups 54 yoI'I(sl?iroconceriEseuiEh.oiy.uk Barbara Cline MBE The difference Is you Generoslty that lasts for geneiatlotts The Charlty has benefltted from legacy glvlng in the past and we recognise that thls can be an Importsnt way for Indlvlduals to Seave a la5tlng glft to Yorkshlre Cancer Research, To help r￿5• awhr•ness of gilf15 In Wllls, we have partnered wSth two Wlll wrltlng provlders t¢ offer 5 tree servtce vla our web￿te. We have 61s0 pjt tooether clear and Informatlvè guSde$ foithose ceA)slderlng leevlng a glft tolhe Inromg li¥m l¢y¢y gfvlng 56 yorksl?iiEcohc¢riEsÉaicli.org.uk Gordon's story FIURA LDNION MARATHON 1996 •LIT17fN Review and Principal .. Sources of Funding Trustee and Strategic Report saves lives The result5 for the year are set out In the Statement of Flnanclal Actlvltles, The financlal statements have been prepared In accordance wlth the accountlng pollcles set out In Note I to the financlal statements and comply wlth the Charlty's Articles of Assoclatlon, the Charlties Act 2011, the Companies Act 2006 and Reportlng by Charities, Statement of Recommended Practlce appllcable to charities preparlng their accounts In accordance wlth the Flnancial Reportlng Standard applicable In the UK and Republlc of Ireland (FRS 102) (effective January 2019). At the stsrt trf th& tlnènclal ￿tsr, th• COVIO.19 pand•mi was Èlre8dy be9lnnlng to m#ke It$elf felt and thè eff•¢t$ have contlnued throughout Iho year. Opportunltlès for In peison fundialslng for Ytsrkshlrè Canter Re$t8rch hAVt beon severèly affected. The 5hgp closure$ hwe nÉc8s51tated èswltrhto onllne fetall. We are a metJl¢al charlty ants the pressure on th¢ NH5 coupled wlth the focu$ on COVIO-19 for medical prtsfe$slon81s hasseverdy 8ffected manyofour fundod programmes. Wtaré ￿*re th81 thedlsruptloA of carterstr￿ces throughout Yorkshlre 11 hav• ah effect f￿ yèa14 totome. Desvte these ¢hallengoi wo are thèrel¢r• glad to repoi* thgt we have stlll been ablè to PTovldÈ EI0.9 miiiitsh of ¢trailtèblè èxpendlturè. Ourfun(traislng Incomewas E4.2mlllltsh{É5.7m 191201 and we $8w a In our tot rèvènue from dN9 royaltles to E15.3m IE12m 19120 X With Careful SI￿0rd5￿p of the money entrusted totht Char5tyi wo saw a risg Inour Investmènt roallsed and unreallsedgdn of £5.2m1-£2.7m 19r201. Futur¢ d¢slgn811¢)ns [￿reSetItIng research awards •pproved by tho 7ruStee5 whlch are not yet payabk ho not been IrKluded as Ilabllkles. An approprlaio amount of rrestrlcled fuThJs has been deslgnat¢d to cover Ihe$ea ture award5 as shown In noi¢ 15. Deslgnatbns for future awards lots￿e￿ E47.9m ai 31 March 2021, an Ihcrèasè of E9,8rn fron) the Ooryeariotal of£3&1M. £4.2 mlllion. Almost decades ago, researchèrs att￿ Urfverslty of Sheffl￿d, fundè£S by Yoikshlre Cancel Researth, successfully demonstratèd how PARP Inhlhltors coulLI be US￿ as a tailored cancèr lieatmenL Thg discovery was P8tent-prot¢ctéd and Ilconswj to KUDOS, a pharmaceutthi company l)ter a¢qulrod t)yAstraZeneca, whocontknued lh$ devowment pr(*ess. Fol￿n9 cllnlcal tr1815, drugs. . Incom.e.,.. ... S9 IrKkJdhg Lynparza, Zelul) and Talzenna, have suctsssfumy reCe￿*d regulatoryapproval arid b&¢i)1>sw91)t to ii)arket astalh)red trèath)entsfor cancer p8tlents wlth certaln hered1tsrY£a￿Èr￿ As a iesuli of the success of th? dlscovery mwjè all￿ Unlv*r$lty, whlchwas funded by the Chèrlly,the Charlty's share af In¢om? Irom thÈ Intellectual propoily Ilténsewhlth underplns the dr￿$, has enabkd Yotkshtre Cartér Rèsearch t¢ sei up Iwoféstrleted funds fr>r further research at the u￿ver%￿1y. The funds wlll use an Èlement of thé Charlt￿5 revenue recelved Irgrn Its sknr¢ of the Untverslty's roy8ltle5, derlved from 5ak5 of the drL4S, to Suppcrtcancer resesrch scr05s the UnfvEr51ty for at le•st tho nextdecada One fund wlll focu$onYrKk%hlre Cancer Raséarcb% stf3te¥c oblectlve5,whlle tho other wlll supportthÈ Unlverslly's cancer 5trat£gy. The Fund5 4re refèrr¢d ta ès the YorksNre Cancer Research More Llfe To Live Fund and the Yorkshlre Can¢¢r R05¢arth Shgffiqld Ploneèrs Fund rèspèctlvely. The net movement In toial fu￿5 foTthgyvrwa5 & surpbJs of £12.5mwhlch when added to lunds brought forword re$ults In fund balances to cariylorward of £69m. The$8 total funds are splbt between gertrèl funds ot £8.2m, des¥nat¢d tundgQt L41,Yrn a5 noie4 above ana iesirictea funds ¢f £12.9n As ststed In Pre￿ou$ reports, fundln9of retharch does not nKe554rf1yltJkJw the pattsrn of InEome wiil¢h the Charlty recdves Irom year tg yoar. Envlronmental Cfltéria ￿nSIder￿(wO company perform5 a5 a steward of n&lure. Stsdol crfterS8 exer￿ne how 5t manageste￿tIo￿sh￿s wllh em￿0)ee5, 5uppIEers, cu5tomer$and t ¢oNmunllles where it cperate5. Governancedeals with a Comp￿sA$ bide14hTp. executlve pay. audlt$, hlernal controls, sharehtsldèi r1￿1 Our Investment martgers are expectedto take account of ESG lssu¢s In thdr Investmèntan81￿19 and decL%K)n- m8klw proc•55e5. The Trusttès ￿&v￿W thvéstmont pe¥fonnance 4991rtsi opproprllte tenchmÈrk$, At thèyefirend Ihe performm of Ihe porlfollo 85 8 Whdewas ahèad of the 99reed ¢>ver811 btnchmèik of CPl+3%. IhoTru$t•t$ olw employ the servlc¢s of 8n extèrnal IrMèstmÈnt coAsult8nt oh an amual ba$1$ to revlewlhe pÈif0nXÈ￿Ce of the knvèstment Managers. At 31 M8rch 2021, the Mlrkét vaHJe of Ii)vostment portfollo w8$ £32Am and Included an unrÈ8llséd g&ii re¢ovéiy to 9ltsbal stock market$ foiiowlrig thÈ Imp8etof the Covid-19 parnlemie In March 2020. fxjrlro the yÉar, Investment portfolb Incom wa$ £68Bk per note Z, and re)li$efS losses We￿ £430k per ntsté 8. Investment Policy and Portfollo The current cllmots creates a iouoh fun4rai￿n0 ewlronment and thls Is Ilkèly ta contlnue for the yèar ahead. Hmver, we are comm1tted to the research weAre The maln Inve5tn)ent portfol￿ of Ihfrchbrfly has been almady furrting and to maklng lurthér awards thls yèar. manèged byQyilter Chevlot 51*)c? Morth 2013 4nd In Cancer resèarch Is more vlt81 than ever and thèt15why December 2019, a new p¢rtlollo w8945tab115hed men9gea durlng 2020121, wè an￿UnCed £8.3 mlllbn In now re5eBrch bysmith & Wllllamsen. fundln9 for future years. Income Generatlon Is a Challenge W+ C8n and must meet. Inorderto eontlnue to save Ilve$ lo Yorkshlre Canrer Re5eèrch hp5 a detalled Inv¢5tm¢nt pollEy Yorkshire, b(>th now and In Ihe years kn tomè. whlch governs how ourfunds are Invested. The Charlty adopts a prudent and well diver5illed Investment $trolegy, almed at balanclrwj potentl81 returns wlth epproprlale ve15 of r15k. The portfollo Is INested Ina rarse of assets sn Ilne wlth pre-agreed 85s¢1 allo¢8tbn$. A5 Steward5 olyorkshlre CarK¢r f4esearcNs capltal, It Is Important ihat our Inve5trrEr)t mana¥¢rs ore ggnalorles of the UN supported Princlplesfor Responsible Investment IUN PRII and that they have IncorpoTBted Six on whith it is based Into thelr Investment Pro￿5$. In P8Tlicular, It 15 important th&t each Investment m&Se conslders Environrnent&l, Sotial and Governan￿ IESGI factors alongside tradIt￿n31 tiriancial metrics. En￿ronment?1, Social and Gtsvernance IESGI triteria are set of standard5 to 355e5s a company's operations that Investors. such as char511e5, consider when rèviewirYJ their Investments.. Organlsatlonal structure The Ch8vlty Is governed l)yArtldesoY Assoclallon ¥thlthset Dut the ChaTIty'5 obltds, Its powers and Ils corLStitutbn. TheChartty1581sogovernEd by Its Board ofTrustees.the stees of the Charlty andthe Dlrector$ of thotharilable company. The fruslee5 have legal reSpon￿bIlItyfor the slr8teglc dlrectlon and effecthe oovern8nce cf the Charlty and for ensurfng thJt the Charily lslocu5ed onacNevlng it5 objerts. continue5 to be f￿ancI*llY and use$ 15 re5ource5 to deliver m8ximvm benetll The Btsard tsf Tru5tee5 mel 5eventin*$ (lJringth¢ ye6rvh Mkrosoft Tea￿. 60 yoi'l(shiroLancorioseaicli.org.Lik T ustee and Stmteg C Report Thè Chalr of Ilw tharfty works Closely￿Ath thèchl Execuuve to ensure that Board dedslons *e acted uptsn d the Chartty Ls manag6d èffe¢tlvely,'thls lrtcludÉs dovek)plngand agr•elngth•straiÉgk dlrettbnof thÈ Chariiyfer apJ)roval bytho 8oard. panel. Thè assessment proc&s Is audltec$ appioved by thèA4soclatlon of Medlcal Regearch Charitleg. Final appro￿1 of fU￿dIng is tesÉrvÈd to the Board. Awards are made underthe terms of a blndln9writtén Iramework Indudlng torm35 Award Condltlons and Pollcies lar Awards. Applleants are rwulred to 2dhero to best practlce standards of research governance and ÉtNcs. Other formal terms deal ￿th tho haftdllng of Intellectual Ouw Trust¢4s ¢¢nfirm that thoy have referred tothe c￿rIty property produced by the research and Its potentlal Commlsslon'$ 9en8ral guidance on publlc b8nefit when ¢xploltatlon, to Ensure the ChaTlty's Interests Bre yotected ievl4wln9 our prlmary actlvltles and oblectlvEsand In and that. where approprlate, a return on publlcly donated nuig ¢ur future 5trategyand drectlon. PLAJllcbenefit fur￿$ 1$ made. lsat th¢ h•ait of what wé do ès a charlty and thls Is démonstY*tod ltt thè Ilfe"91v5ng medlcal breakthroughs made through reièarch funded byyorkshlre Cancer Research. In 2014. Y¢iXshiFe Cjncei Ré¥e&chfuhd¢d è world-flrst, Lynp4rza, a drug da￿￿pod In Sheffléld, ￿¢3M¢ th&￿TId,9 flrst Ilcen¢ed PARP Inhibltor dru& s(tCCéisfullyèxtendin9 th Ilvès of women wlth a eertaln type of #dvèncèd ovailan ¢on¢4r. Sln¢e Its launch, thedrug h85 also been Ilcenced f¢rys¢ for￿me 4dvonced breast cancers, pan¢reatlc ¢8ncers and pro$tate cancers andirla15 are on*olng to see If It¢ou￿ be eflectlve agalnst s¢veral othercaneers 10th In addltlon, by showlng thot PARP Inhlbltcrt con bè made to worK Lynpar2a hai ￿rtsId1d thè arrlval of othèr si￿1￿rty￿S of cancèrdfu9s, provldlno patlehts wlttr) vltsl •ddltbnal trèatmènt optioni. Public benefit Regular meetlngs we held durlng the cenductof the Aw¥d wlth Aword14olders to m¢osur¢ pr¢gra$s agoSnst 8gr¢¢d keyperformance Indl¢ot¢r5 to as305$ progress aga5nst Aword Imp8¢t. £10.9 mllllon In;. fundlng:,, Yevenuefrom royaltlès wè recè1￿ from Ihè ¢Srugs dtveloped Ès 8 result of these LYeakthrou9hS 9¢ stralght b8¢k hto fundlw furlher re$e¥rch that wlll chawe Ilves thè fvture. Fundraising Standards Atyorkshlrt C*nc•r Research, we w¢Yk ￿rd to athleve best pra¢tlc• In furKlialslng. We want our SUpp￿ters, éonDfs and anyone who corne5 In contèct ￿th u5 to fed theyhave ljeen treated wlth re$pect and con51doratlon. We $ubscilbe to the Fundralslno Regulator and Code of Fundralslng Practlce and actlvely follow thelr guldance In parallel wSlh that reeommeThJed by the Cl)atlty Commlsslon for Eng1ahu and Waits. Our IrKcme GÈneratlon Commlttee focuses speolically on lundral$Sng actfvity and the Dire¢tor reswnslbie forYorkshlr& Cancer R8searth¥ fUTh*al￿n9 aCt￿llY rfrport$ to this Cornmitiée. We also take care to monltor and addr4$5 change5 In re￿Vart reguL4tIc that may not be 5pecltlc to chorltles. such as the GDPR legblg11on. 40 000 le 'have been". prescrlbed wlth Gmnt Maklng Pollcy Re9earch1s at the heart ¢)f al we do. Eachrese8rch award thgt Ls fvnded must meet the Charfty8stfategl£ al￿￿ to prevent, dl8gnose or Ireèl eart￿r for people In Ytx1ven onthe structurè and governance to the applled lor ptsst. of thé Charbty, moetV41th thè Ch1if Executlve and ère •ppolnted to o Doard Commlttee, New Trustees recelve Jn Induciicfi pack of keydocumènts, Includlng a contract of commltment. ahead of thelr tlrst meethg and •o r¢gulr¢d to Work through these decuments the Company Secretary. Any Immedlate l¥&inlng net7al pkins and manage th Charity wSthln the Inllghtof Its publlshed straiégy. Thèy ihose del￿ated authorltle5 and BccountaUIIty framewwk$ actlvltles ¢hosenfar prbTltlsaUon Snthè most ie¢ent lald down by Ihe 8oard strateg1¢ ￿annIng procéss and fevlew the Impatt that th• Ch&YSty hÈs a¢iuany ddlvÈrÈd. Board support- to ImFlement Board de¢l4on5 Bnd ensure thwie￿IYe1hQlnfQrrnat10n and advlc¢ It￿Y the PARP Inhlblter Commlttee, whTch has dutle5 to advke and make reeommEndJtbns earKernlng certaln m?tters felaurwato the charb1￿5 shareof rÉv8nu8 arlslng from tl* family tsf dbug$kikn)w as PARP Ii)NL)Itor$. Statement of the Board of Trustees, Responslbllltles Remuneratlon Policy ctiarity ind Company law I'equlres tlie Twgteès to prepar• Ilnancial statements tor $a¢h Iln)n¢l81 ￿8rwhkh ghe tnje ind lalrvlew ol the slate of affolrs ol Yorkshlre Cah¢¢r Re$eer£h. In preparlno thD8e Ilnanclal statements, Ihe Twstoès havé lollowed best pract5cé and,, The diorlty has 3 reSp￿sE￿IE1tY ttsensuré romvneratlon 15 8PPiOPriate and affordoble and alustlflablè use ¢Jf chbrh8blelunds. The oty¢ctlw5 of our Rtmtsn•ratTon Polltyarè to.. • rèward all employee$ basedonthelr Bkllts, pwfomionce. ontrlbutbn and commStment to Ch•rlty • enèkA¢ the r¢¢rultment, r¢tentlon ènd rr￿￿valknn ol • selecled sultable accountlng pollcle5 •pplledthem COn￿Sten￿Y ¥each¢d judgement5 and made estlmate5 that are Con￿dered ro8$on8ble8nd prudent st•ted whethEr appll¢#bl• aecountlng $tis)dards an statements of Retorfmtndtd PrAttl¢è have be¢n followed, sublecl lo ony materlal departurè5 dlsdos•d and èxplalned In the occ¢untS onsure th¢ prgper and effectlve use of our resource5 wltttln s¢n$lbb. 4ffryd?ble lirnits basqd on the Ilnanci heatth and the $¢rateglc glms of the Charlty be falr and equltable In seltlng and m¥na9lng pay I￿15 so ￿ to provldg J rgllable andsts5taln•ble framework for rerNneratlcn, freo Irom d1$thr￿natIon clearlydemonstrated. and rèporteé on. the publlc b•Mfii a¢hltwd by tho tharlly FYep8red Ihe flnancial 5tateYrtnts on the g¢in9 Wl￿ge8ndUnder5l8ndlrvOf thecttailtyand Itsen￿lonMènt(1)t8I1)e($I￿ th* tourseof Ihe 8urSlt, we h8ve not Ide￿r￿dmdtellal mlsstatémtrnts in the Slraley¢ Rep¢rt Dlredois, Rewtlndudedwlthln thèTNStets'Report. Wè Fmve nothlngt0rnp￿È In respectoflhef0ll￿￿t¥jm8tte h r*￿tIon1(}￿h1eh th8 Comp8nkpsA¢t2th16 r4ulrasUSto reporttoyou If, lfj our0p1n￿Th Irt*guL4rlVei In¢luclhglMud,aR inst)ntésal#oM-¢c¢np￿￿¢e wlth laws ondr4ubtl¢ns.Wtdeslw proc4duresln Ilme wlth our respon￿bIlItIes,¢JJtlInedètstsVe, todèteet Materiol mbst8tsments In respectof Irrylarltles, Indudlng fraud. Bgsed on ouruThYetstandlNJofihethortyfjnd Industryi wé Idon￿fE•d ihètth• prln¢lpal risksof n¢h-tsarnp1iancÈ wEth18ws andrègubtknsrel&ttdtotheChArtilesA¢t2011 theCh3rlllesStatémÈnlof RecoftThèThléd Pracbtè, UKIOX slatbn, penslonsle91sh￿0n, empbwnt rtyulètlon and Iwalth8nd satstyiegul&tlon, 2ntI4)ribÈry,corruptI￿ and fraud, rnon•y Lgun(1gring, N)FFc¢miI18nowlth irtv￿M0nt￿￿0n of goveinmenlsupport 5ch8mesrdatingtoa)viD.19, andwo 8realSOt￿ DirectorsoftheLharltab￿ c¢vDpttnyforthe purposesof ¢omparylawlare reSpo￿￿b￿l0F the weparatlon of tFEll￿rK￿l 5tatrment5andfor beingsatirfied that they gweatNe andlarwlew,a￿ for5uch intemolc(*rtrd aslhe Trustees(ktennine15 neos5WytoeT*ilethe prepaiationof 611 yorkshlre¢ancerreseoitli.org.uk Shaun Mullins (Dec 21, 2021 14:16 GMT) Dec 21, 2021 Financial Statements Consolidated Financlal statements Consolidated Statement of Financial Activities (Incorporating an Income and Expenditure Account) for the year ended 31 March 2021 lJr*•std¢t*d 2DII T•t•l 20Z 2021 20ZI IrKomlng r•soui¢•s Donatlons 1,312,198 74,WO I,YB6,198 1.848.218 2P26,392 1826,J92 3,829*60 Ifftstment Incgmg 707￿68 74.396 782,064 1,058,74S Incom•lrom 7A61.816 7A32A16 LS,294,4 11,960.114 12, jl 00,074 7.761,012 20.28g,OB6 18.716.737 Re8oure•$•xp•nd•d Exp•ndliuréon fundr￿￿n9 EMP¢n￿l￿re¢Th thiiii8bleicu￿tJ•s 2Jl?,S 2,121,312 2,286.347 5.867,S87 5,026,240 10,891827 8,0￿.214 Yotal iosour¢o¥ oxp¢nd#d 7,9B5,261 5,029,075 lJ,015,139 10,3fj1.SGI RIal￿d unreallsÈdo•lrtslQ*¥$lon Investmertassets 5.202,OB7 1118S71 5,188,230 12,725,9651 Not Iii¢otho 9,714.997 2,73Y.180 12.462.177 5,629.Ul Tra￿terS between funds 180.7641 60.764 14et mowmonts Inft4th 1664,233 2,747.944 12,4S227? S,629,211 Fund baloncos brojghl foNard 46,510,192 10,056A26 56,566,91B 59,937.7Q7 rund l)olon¢¢s ¢arrl¢ilfQ￿Qrd 31 m￿l¥h 2021 .17d.52 12.054.570 69.021095 J6,S66.918 Allof resLAts8rÈ dÈrwvJfrom£ontlnun98ftwltle5. ￿l93115￿d I￿eS reccgnls&¥ Inlheyoararelncluded Inihoab¢wè. Thènates 176,900 ISOA91 vllstm8nts 40AOB.OOQ 28,172,070 Progromme relatsd Investments SSO,057 41,154,957 28,322,961 Curr•nt•$i•ts Dtbttrrs 6,40435Y 9fi91,5B7 ock 4011 C￿h it bink end h)hand 28,109,451 21200,087 34,SlS.BII 31,897,OBS Cr•dlt¢y6'.JmwntshlHng du8 Yhlhlnon8yeai 16.614.428) (3,653.7281 Nat¢uri•h¢•si•ts 17,9c*I,383 28.243,957 119,036,340 S6,oVfj6,9111 Fund G8nqrallunds 8,237,452 375,061 DBs4unit•61ur￿s 47,944318 38,135.231 ResirlctedfUr￿J 11854,5 LOA)56ffj26 yo1￿1 luii¢ts fj9,036.34Q 5fj,5G6,918 The linandal staternent5were approved tythe 80ord of Tru5tee50n 16 December 2021 andsiwedon Its behalfty.. Graham 8etvllle-Chèlr Th¢not¢s onpoges 75toYI lormportof tAos¢fhtoJ]dtrtsfatemenlS 73 CONSOLIDATED STATEMENT OF CASH FLOWS for the year ended 31 March 2021 Company number: 1919823 202A N•icMhprwIrt¢dby¢pwiin>￿I￿lIIl1 17 17A32.790 659,OP7 •¢uvi¢i•$ dènds Ind h1•r•Sti•￿￿td 781064 LO58,74S Lknre811sed 5nvestm•nt lolrAyk)5S•1 I4,758￿8) 156316 Pyrchose trf t4ngbl¢ Ix¢J )$$¢ts 18¢,90¥ 18431 Purthtsse ollThvesiménts 123,667,597) 11&84L5431 Sil•nf In¥￿1￿#Th￿l IQIW417 19,fi?5 7fifi Spl¢¢f Invostment wepertlos 865,000 Deciease Interndep¢s5tS IAg1,23 111,534,567) 6.e69A23 Ching*ln ¢•5h •nd c•¥h wulY4l•nts lThth• f4POrtlng pfrrlod Cathand ¢*h¢q￿V&¢nI$lllApr1I2o2o 7,328,920 22,zi&fjzfj 14889.706 Qjsh oiid ¢b511 ¢qiilv•l¢iits&t 41 Marcli 2021 li 28,116.711Y 22,218,6ZS Inchinggs In ngtfund5 AtIApth2020 C•ghll•w> At 31 M•rch Cash ind whequlvalènts ,214626 S,898,163 28,116,789 Tot41 k2,218,626 4',gy8.1(13 28,ILfj,789 The￿Ie$0￿￿1gQS 75to 91 formpJrtGf thESe lAnone¥￿statérnÉr jd yorkshli¢coiir¢i'reseuich.org.(4k ConsolSdated Financial statements Notes to the f inancial statements for the year ended 31 March 2021 Accountlng pollcles Ley¢k$ Inwme JrYJlnqtromlegacies15 recognlsed In Ihelintsnck)Islulomonls whenyorkshlrecèncei Rel￿rch h notilied ol th*lr&rntit￿r￿trtl til+ 4mounli¢¢¢￿Ibleel￿t¢detwffjlned￿llhreO%o0￿r¢1glFtci¢dfunds4r¢luiids5ubl¢ct t9 5PQCillc rosirl¢tivecondilbns ImpLw6 bydonor5 0rbyth& purposq of ttk9&P￿o1, Tho purpo*And us*otÈily r￿1￿￿tÈ￿ thr¢ $&tlxil Inlhenotes lQlhé flnamclol 5laternenls. All Irtome•nd Èxp*ndltUi•Jresh￿l￿th￿sI&temenl olFln8ndbl Tan9lbl¢ flx•d is$rts and depr•d•*lon TbngiN&flvd F$$¥¢>41p$I?led&t C￿l,1e￿&epfv￿oI￿n. OewecibLionlJpitsifyded ona1ltèng￿Ièf￿At￿ tslsthlg bt IBt*i 0￿culo1￿dtO wilte Otit￿￿110￿03Ir810￿i IIntbP￿1£O￿8rih￿T •xp•ct*d u5•1u1 Ilve$b%l0ii￿'. Lewhtskjwoperty LetysehDK*rei•iipfoperty MolorvehlLles O￿lce fuiniiure an64qulpmant IT•4ulwwni I0>￿Ti 5 yE•rs 3 years 5 yÈ)rÉ 3 y¢ar> Ifwestment propertles InYtstsY¢ni proF*rtle$tre$rthn it thtrlropej marketvalue.If surpldsor d¢ficlt•ri5iny Iiorn tli¢annu41 ￿1￿J￿1)￿n ij li4nsferrcd the knvgStmpnlrevè￿4tI0n Teserve un1e55 adelKlt.oi lis reveisèl,on an hdlvldual Investrnentpropertylsexyctèdto bQ pQYthI￿nI, hkh£J5e ￿15 rttopni5edlnthe StatenierÉ of Flnerti&1 A¢tI￿t*SfOr the￿r. Ineomlno resources co￿￿ngreS0UrCts¥erèC0gnlEodWhPnYLY￿￿￿c1nQrR¢$È•r¢tt con5kleiediO t¢pr¢bèble. Glftsrece5vedlorre5Jlc orerecoided whfrnfney*i* 50bJ. S￿￿CeSpr0v￿eltb9￿hjnEIer5•rtt notbrO￿Oht Iiito accourt. 75 (Note$¢ontlnu•d) In￿StMents~ quotsd IfwQ%tmont% ar&stbted li mafkètvalue ahywoV￿drttoferr¢d t•xallon D¢f*rr•d t•% l$r¢ctsJnlS+d In tèsptet Of i1￿minD&ll+l•￿￿$1llal haveor4ln&ted but noirevsiserl•t lh0ba1ancesho￿d￿t￿￿￿￿re tr•nsactlonsor•vent•htrAdEcuirèdtsithJl wll r4wlt Sn 4n Thtc¢ltl¢il$¢¢¢uniingP¢lkyludgÈmèmsihèl thèTftl&ttii h8v• ffl&¢e Includ•¥￿15$1￿Q In01(￿1$011mP#1￿MoiIt ond IhgféCO9nltlr ol *11¢1os If theré htswbeenonylThJlc8torsollmpalrmehi ID 1¢14tKin io•51èt*tbèTrubie•6 hbve ¢0o¥ldired ¢xrwii?I *ndlnternalsoyr¢osof knformjiion 5uch4s mirk•lcond5tk>ns. counteFparty9firttsPo$•l ol tlxod bBsoi% that have been iolledoverliilo iopl)¢itshni •ss•t oniywiho tmt, atth203lwKeshpet d&le.thWQ li ¥blndh¥ B9rÈeniÈm WdlSPO8e Qttbè •ssèu<•n¢ern¢d Ho¥vever.4opiovtsFon Is modd whoro,OThthg ba51sotall av4llable Q￿dIn¢4 01 thobhlJtb¢èshè$td&te, It Is Mtsr not tkn% thÈ taxBble9alnwlll ovèrirt¢O le￿￿¢¢m¢nI￿sstlsondthJrge￿tOtOx9￿i¥whe￿th9r￿￿oc1￿￿I 055ptsarp$¢id Oefrrred taX4sseisoiefecogDIBed tstylylotht OXtOllllli¥tlli¢ TrUSt￿5(0n5ldcrth*1t15TDgIC IIke￿Ih￿n1￿tIhatl￿rftre￿II1 btrgthlablè tAx￿b￿￿1￿1jtsTctsM￿h￿h thpliiliirp r*vwFAI thf thA Unaèllyltso tIm￿9￿lfarénC￿s£&n bèthRdU(tod. D¢f*i¢¢dtsX ismeèyJred on bn undlscounledb1515attlietaK IJtE5 thataiaey¢¢ed tO•PPlylnth8 pérbd51n V4hlchlmln¥LqffeittncesrweIse,ba5￿$tsnI￿r￿lOE￿c{l*Wg enactedar5ubst1nt￿etyen{cted alt?￿baL￿rK¢$heetdatt. Lega￿•$•rÈ 18c(la￿sta￿￿ThthI Incom• Cftt•ilawe Cons￿￿￿￿￿E9 ba Th*1. In£omè Insi•n¢és thè not bttn i•ppiieoio thttvaivauon Of th¢ f•g¥y. Inthtte ca9es, opprcyFLiteprofesilongI2dvl￿ mtybt ¥ought toJ¥iStwlththB¥duatlonof certsln4SSèts. K•y sotsrces of Èstlmatlon untértalnty Theestlr(pOtesondunderf5lngavsumptbn5 Dre ierfewL* on ¢ngolng ba46. Révl$Ir￿Sta xcounllng osilmaiestre rccoqTrked I the p&rh)d whlrhthe esiim&t*is r¢viseo.11 thè reVw￿ a¢ro£t%onty thltpti￿1,￿r lrtthe pEr14￿￿1 Ihe ftstur¢ perlod5. ItlhE ilon bffects bolhcurient aDdlulur&pei5od5. Ihp kpy aSwrnp¢￿￿str)rtt￿ning thefuturè, and otheikeysowc95 ol estlmèl￿nLVKerIè1*l¢y. ihBt h4ve o Signillc?ntr]skef causin04 rnrterlal adlu5tmentto ¢hecarrylw amwirf5 ol a55eiS 11)bIl￿t5 vlthlrtth* rtè%tfln&nda1y+arère Indicatcl IG yoi'kshiTe¢aii¢¢rr¢seui¢l).org.uk Consolldated Financial statements Determln5ng resldual value5and useful4conomle Ilv85 of Determlnlng thevaluallonof tegaey debtors propertyi plant. ond equlpmenl Thechbiity lettra￿Se5 the lftwme£iitÈrlb hw¢ baÈn The ChartiydeprÈclatestanglblt36%•tS 6W&rthÈlr•siimat*d usofui SatisliQd. Insomts InsL4rttosthe Indudvs a&£olsvhl(h ar ¥ts.The estlmatk)nof ttte u*ful Nvesof A55ols fst)05¢d QD h1btorlc Iqqulred tobvjoid bylho estate tor*•llseihevaluaof the ￿1¢y. p¥rfomi*¢$ 95Wol 05expeclatl0n5a￿Ut1UlUye thereforo Thier•th*rn Is•ndement of uncért•lnty Inr•￿10￿tr>tho￿￿￿t1afi ra4Ul￿#stlthli4S irtd atsumprb￿tO be èpvled bymantyBmeni. Of suchassots,th*CharltymayolX&n wofésslonaladvlu toallow The1ctu￿ lfve501theseassets ¢bnv•iydepe4dlw On $ varletyot Ore leik)b￿ e5tknpteof I￿val￿ totseobt￿￿trd. fACttsr5, Incithllngtéchnoits¥¢¥ Inntsthtlon, productllf¢ 0¢￿and Inv*$im¢nt Income Vnrèstrfct•O R•stsf¢tqd Tot•s 1021 Tot 20ZO Clvld•hd$thid Intérésion Invthmonts 688,207 684207 IP16,040 Intvie5t on bankd*pwlts 19A6L 74.Y96 93,857 42,705 707.668 74,J96 702,064 1,058,745 Expendlture onfundraljlng R•stilct•d UJw•stric IOIL 1021 Toial R•E¢rkt•4 ilrnstrl¢Md 2021 Toi Publl¢lty4Thd fundra151ny $39.701 539,701 725.579 725,579 St•fiw5ts I,o¥ui 1.092,131 IM21,325 1,021,325 and ftTr)torexynsBS 15,767 15,767 17A55 L7.455 Office ￿￿￿1￿￿d011on costs 47,TJ6 47,7 39,7 39,773 officer0pah¥￿d renEbYa15 5,270 S,184 5,IB4 Prlntha, 51alknwy. postÈyo, & s￿￿￿¢$ 15@019 156,Q19 192,586 192,586 Le0¥1 and Profe￿10￿1 5ervke5 7&0Y3 75,OYS 3,962 114.325 118.2B7 DepFe¢iati¢nand profitond￿Po5al 28A61 28.461 1&317 18.317 Co$tsof tr4dEng4thvitlo$ 63,002 63￿02 36.188 38.188 Inve5trnent manaBernEntfee 3,735 9&.192 81653 89.653 3.735 IlJ7.577 2.Jll,312 ?.9SZ 2.262.3&5 2.2￿.347 77 (Nat•scoAtlnu4d) Charltable actlvltles 2021 l4tsofGr￿ts Ineuffad tncurmd E￿t￿le U#rèstrictéd Grants PJy*￿ Resea￿1 p¥o1¢rti. prcgr•mm*i, 8ndf*clfltl•$ L￿￿eTsItY01 Offadfor 25,2B3 3q515 Bradferd CCG 127,050] C•rdEff Unfversliy 41.688 4fj42 Lhlveis5tyof Hull 204,938 774354 1,281.767 lh1￿151tyolLee￿s 17 2,99&733 363.384 14b19,￿o LEedsatyCoune 250,622 937fi01 LBeds BtckettUnlv*rslly 7.029 ith￿rsIty•f Marrthester 49,293 49,692 Un1ver51tyColkge London 29.100 I,S57,517 Lknbkrsltyof ShÈfflèld 103,S45 268,597 3.530,759 Shoff1t￿ ￿￿101￿ Uiil¥ers1ty H•rfogate fjs¢il¢t FouTid•tlonT(usl 13S.2771 l￿W(astie Un￿er$Ity 44706 lthl¥eigltyof NOlttr￿h)M 526.850 797,907 NbrihurnbNa Un￿OIs￿Y 85.933 92.124 Tra¥*l output monltorlng,CrfflrnuDlly ￿•￿t￿￿1 mlsceManeou5 Kems 12 1SS,804 4,072,271 Subto IAOfj.13$ 20974.395 l￿￿rGItytsf Sherrie1& En(*Jwmont Fund reiurn 3,￿9.905 Rever1￿ offnpglrmeniof PIow4m¢ Rd•ied Investmertts Support W5tstsoBbok)v41 (55Q,0571 1,872,280 om8ncécos¢s 40,512 49 5,867,587 SP26,240 26.9Y4.39S Ih•luiw¢dosloatbDs Feprtsenlrtsearch￿wdS8Ppro￿eo byt1￿ Tru5teesv4hlch BTellot yet poyaNo Thosetwenot beenkncluded libbilltles. Huwever, aDsppropiihtefAnountof unrestflcted N4sb1￿￿I%14n)tsa to¢o¥irthwfutur4 aw8rds8s shtrwAlnnotè I ThpfutW¢d¢SlW4tk)nsAbtsw IrKiude grantscuYrenttyawaid*6ortobeaw4ideO InfutuFefromth* iestyiclèo fu￿$t0t￿l￿9 £12I54,570 Inthe Bal8nceSheei?nd &de5crlbed h dplill InnDtelS. 78 yorkshii'Ètaiiceire.%eoich.oi'g.uk Consolidated Financial statements Noal Grnr ijiturféd IrhCUitéd Firtu¥• uttrèsirictèd RO6trfrt&d désignavon& Gr4nt%p4y•bh.' UAverslLyof 8rtdford 162,629 s5,￿7 Bradford CCG 70.093 CaTdlfl Untvltslty 113312 46.330 Un1vÈr￿tYof 301,143 560382 IA42,1 u￿v￿r￿tY0I Le&d¥ I533￿96 593,227 9,728,628 ed5 Cllyccundl 90.367 1,72d,133 Leed5 &e¢kntt un￿er$Ity 36n80 27,304 Loeth NHS (7*011 Unlverltyof Man¢hgsler 75930 98,985 Unfv8rltyCollBge London IS9,514 593.761 unw¢￿ty&f 5h¢rri¢ 236,$B6 360￿6 710,896 Un￿81￿tY0fY01k Hari¢git• Ol$trl¢t FwrKl*tbnTrnsl 92,961 a45,￿1 vcèstleun1ve￿Ity .210 S4￿71 Unlverltyof Noltln9h?m L61A8L 794.206 Northumbrta Un1v*r￿tY 96fi36 111,441 Tro¥eLrAJiput monIt￿l￿o•cOMm￿tyHaèlth,￿Ad mlice1￿m¢Us Item8 317.193 34,359 74,386 Supporteosts(se+bebw) 1,208,698 J>so 39,596 Tota5 6,543ts10 1,551,604 IG,007,110 Support Costs Tow 2021 Tot 2020 Slaff costs l.Q27.748 687.479 Travd 4nd mUtor￿S￿2nEQs 14137 li,X9 0f1ice4cwmm￿at￿)ntOstS 441.gZ3 26,773 Oflice repai15ar￿ renewd8 4959 3.489 Prfvtlng. $tatloneiy,posiage, sundr￿$ 146.822 129.635 Legal and prof*sslonalseivl 6(6,208 340,IIY3 Depreclatlon 26.783 11330 1.872.280 1.212.35B 79 (Noto$ ¢ontlnu¢dJ Émployees 2021 2020 Staff eOSLS YlaguzThl 5BthiL95 1.844.175 IA&IA27 SDclal securky costs 175,417 139212 Penslonc05ts 124,244 101.E06 2.14Y.83 1.725.445 ThB Bv¢r•gtrw*efol•mpbyoiJompkny8dduiInglhtrye•r￿1$ 5212020-411. Ta• nUmb¢rd*nphY¢¢$d￿lIn9tb0 ￿rwh￿09rOs5paY end b•nÉtlislexciuding tsmpwi PdnFADn<4ntilbutloMI fell¥AINn tho folknAn9bund8wo%.' 2021 2020 £90.001 £IOD,OOQ É80.401 É9ts,¢00 £70,001 £oo.oc¥) £GOAIOI - £70MOO Tho EK*¢uiiv*i¢•m4l*hoCharftyumprl%È ihe Éxecutlve, t4iectorof 8Tandind RelJtlDll5Np5, DtrectorOlFlnJrKe￿d CoiporJt• S•YvlceJ,Olrecto101 Raidarch ind sèrvltèsllld Ihè¢omp4hy5•¢r¢¢•ty. Thè t•t11 tmw•y•* b¢ntllt* th• ¢o1¢01 Grnpigyer¥ Naiignal lw•n¢+C¢nir￿ut1vTrsorIh+ Eyg¢ullvgt•imwg1• 1497,54912Q20. £467,JB31. TriiSt+•6rordv•d Mmiin•riiinntni t￿lri•l￿r•S￿ljrfn￿ tts•y•fir Yhvipvwip Dnpwnv.tai L￿r￿trI(tId UM¢sirl¢i•d 2021 4Jrfilots' remune¢ètl¢)n dllfees A9,7SO 17mO NUftai￿kfTres- t*x 8dv￿￿Y$￿.rlri¢p.S 10,890 t)EpreclatEon oF¢)wrÈd J55¢t> 54.894 29b67 ¢>)er8t5nll le85e rent pakl- lèndaiid bulldlrvJ5 95,712 SU58 O yorl4 66A4Q 196,331 262,771 Notbookv4lu• It 31 M•ith ZOII 41779 176.900 31 Mèrth 2020 S5.073 95,ÈllJ Is0￿91 8. Flxed asset Investment$ Group U$ted In¥•stm*nts & unlt ¢ru5t5 Temi Sub￿dI•￿ poslts wJd•rtbkln95 Total Tol•l Marl¢t ¥alue•t 01 Aprll 2020 2>,535.e48 4mL438 28,157,488 33I61l0> 2Q,64B.441 3￿19,156 73*67,597 20,393h2 OL4p(tsèIs a6,1￿,315> (202) 116.190,5171 123,5340851 ctwge5 Tnn￿rketvaIue 4.?58,6d8 4.758,648 (2,$63,4￿) Maikotva1ufrot 31 Marcli 202L 3l75l,fj22 7,640,591 40,393,215 78,157,488 81 (Not#seorttlrtu¢d) Axod a55et Investmwts l¢ontlnuod) Chadty L15t•d Tnv•stm4nls T¢tm Sublldltsry und*rt*klng$ Total & YnRtru￿5 2020 aiket ￿lue4( 01 ApKII 2020 dtlor6 SPts5als 23,S35.848 4,621,438 14,784 28,172P70 33.867,991 ZO.64&441 tt6,14)3151 1019,156 23.667,597 20,393,624 IL6,190,3151 12I669M851 ChirvJe5 In m¥rk•l 4,K8,648 4.7se,648 Mli Ikètviiliie at J3.7fJk,($22 14,184 dD.4011,001) k8.172,L¥70 31 Mmrch ZOZI Ae•lb•d ond unrnill**dgttln$4ln In￿￿1￿*￿1 Group a021 Graup 2020 Chèrlty 2Q21 •rlty 2020 4Z&582 1162,5051 429,SB2 137,3441 4.75&64$ (2,563A60) 4,758,648 I1563￿r*￿ YotslMlls•d Ind unr••llMd g•ln$llbis•il 5,18B,230 2,ns,98$1 S,J88.230 600.8041 Hlrtoilcolcgttoilnw¢stffAnts 29,314, 25A)9,578 29324.980 25.600.378 R¢allsctJ lossos bH5ecl onhlslorSt cosl 1681.S151 188,349} IG81,8151 168.3491 11?. yorksluiecaiiceiresettrch.org.uk Consolidated Financial statements roup 2021 Group arlty Chorlty 8rl¢KshGovernmentsecurf11e5 1.121,704 1,582,929 1,121,704 1,582,¥29 UK Ilxe(I lt¥ter¢st$é￿rfi￿ès IW,691 9,739,94S 3,2?3￿11 9.739.945 -11sted on • recogn15edStock EKhange UKequltystcurftle6 9.059.724 S,534.310 9,0S9.724 5,534,310 - Ilsi¢4on4 r¢¢¢9￿$¢4 Stth Ex¢hanUé un￿ tr￿- Itwested InUK eqult*s 13,103.250 4.061A53 13.103.2S0 4￿61￿53 Lknlt tnJsts- I￿e$￿￿ Inforèigrlwtttss Other Invt5tment5 4,978,900 1.390,563 4,974900 I,3￿,$65 L255,353 1,226fi49 1255.%3 1,2Z6ts49 Y2,752.621 2J.SYSA49 32.751,622 23,535,849 grfIL4hG0v¢rnrn¢ni%eEwrn1¢5 i¢pr¢sent 4.2% ¢f tnetsi¥1v•￿jo{2Q20- 5.9 AI 31 2021 noone ￿ldIng •Ktetted ￿01th￿valU￿01 Ihgporifdlo131 M•r¢h2020no on¢ ￿l¢kno I￿•￿￿1￿￿). Th•lnv4$tm4nt p)rtlolbw•5 edrflnlstoredtyQullloICh￿tst Umlt•dandsffJth & WIIN•niityN. Sub￿￿0ryUndOrtlkl￿gS 2021 Wood5 8ac¢n Faci¢ry Llrnlted-valL￿tltsn at31 M&rth 2021 14,582 14,5 Y£.R. PrOn￿tI¢ll￿ Umlt¢d-¢ts5t 4131 March3021 Y£.R. SclentifkO¢v¢bpnv#nts Limited- C￿1 ?131 M4r¢h 2021 21¥J IA,704 14,784 ¢ods F•¢toryLimiithJ. acornpBny ie 91siÈpe6ln Erythndand Wklei (Componynu¥rkn&i 0034790a) k* v4hlAtyOWnÈd£￿£ld1¥Jry0I YthkshlrdCèn(erRest4fat 31 March20211s £7,337. Th•c¢)mpany$tuinwrfor thè y¢Arlo3lM¥rch 2021 ¥v4sCI?8, tts EXPEndllvrelor the Seme p9rlod%vg¥ C7,423. W¥od$ Oèe¢nFxioryL4mited hasi 31 MDrpaymtnlsol thlsnatwedurlngtheY￿ar (2020- Enlll. Tnecv*rllyhtss prvlded wogiJnV￿ ￿1•1¢￿1￿¥t$1fflQrtstothtr 1¢￿0￿1n0(0rnparf Cl%%14 8l•t¢chnology LIMl*éd Gioup ind Charlty Investment Tot Cost QI Aprll 2020 S50￿57 550P57 Addlllon5 Mirctt zozi 550)J57 S50￿57 Imp&limenl 01 Ap¢112020 550M57 550P57 R¢vor4 d￿nythI￿r Issoos? (SSOn57) M•rch2021 50,Q51 31 ilarch 2020 Ihe kn¥p5tment Inat1￿1$ knordiNiylpihtrOs￿d Mwo￿ThI1 12.4L%ollheltsuEd sh￿t1p1111. its •gil¥liyr* ¢h•dew¢pm¢n¢ bl¢igp1¢41wtDtswl¢h gpplk4fj￿9 In f￿r￿￿me41¢1ftl Ih• Nsi(*k •CCCyJnllngpL4lcyl4rPio9ronTrft•btsd In￿l￿O￿t% iolNpo1r￿ full cost In thEye&i Ihelrb¥eslmentW85 rn*Jp, C12*1è BhteChn￿1￿Y Lld.¢>nowch programmerolaled Inve$iff*nttyYafkShlt¢c4ncet RèSt#f¢h,w•s •cqulf¢¢tyg¢uld 0pp¢rw￿I1e% PLC ￿n￿pY eGwklQpporrunlllesPLC w8$ iubstquenllyr¢nbm¢dCltle by•ts¢hn¢￿y PLC4nd wa5 adrnltledtothe malnrnaikotof Slork Exchanpeon24 Moy 2021. ABI rw1lof thil Irnpiiim•nt h85 bo*nr4weisEd Inihv Mgich 2023 nnancbIst*t*M￿tS&ftdih￿ln¥O$tffl*ntI1 V&￿tr￿￿the&MOUn¢QTrglnal1ypBl￿ andrepresonis 12.4216of thÈ li*u&d sh&Yc8plt•L 84 yoj'kshlrecaiiceriEseaiclp.oiy.uk Consolidated Financial statements Grwp Grcup 2020 Charlty 2Q21 ¢harlty 2020 Amountsfdltnp du¢wlthlnonewir Tr8dedQbtors 425,261 2,8B3￿73 42S,261 2,883.0?3 otherdeb1015 S9M07 IA02WO 59M17 1,401777 Ac¢iu¢d kgacylrt I.￿￿98 L677.534 1598A98 1,677,534 PrÉpayment#And ac¢wed Inromo 4.322,793 3,728,203 A,322,793 3,728,203 6AO6,35 9,691,630 0.40G,359 9ffi91.587 11. Cash at bank and In hand fjffjup Group 2020 Ch•ilty 20X Charrty 2020 20.116,789 IZ,218,T52G 28,109,452 Z2,209.OB7 12. Cwedltors amounts falllng due wlthln one year ljroup Gr•up zozo T•x*t1on4nd50clal 8tturfIy 41381 75,759 49,381 75,7 Arncuntsowadto$thsldLqryundertakln9 202 202 Res6arcP$6xpendllure 2,OS6,140 1029,9S6 IC66,140 ¥829,956 Othercredltcr54nd accruals 4,￿8.705 1,7s1,811 4,50&705 I,?47￿11 6.614,226 3.657,728 6,614028 3.653.728 Ris•8iCh •XPirtdllurèwm&¥15e5accruilyloramounlslncurr4dtylhe reclpl•nt b2tyuptothfry&arèn6. 13. Operatlng lea$e commltments: Group and Charlty tot8lwmrnitMents undor ow4tlng1845estyre'. 2021 2OZO Rent ptyablein thecomingyear 1SM19,8$1) 136?.U8) 1774.228> (3,888,502) U2n 113mY.?I Net Inve5twRnt 9air61 S.202m7 (L3,8571 S,188230 rr4nsfers Fund5 d￿On#t@￿ Lylry thfr Q5,689,504> 15,828,740 60,764 At 31 Marcli 20?.1 8,23?AE2 17.I*io,ytB 1.585,000 9.41S,Y68 5,037,427 Grollp2021 fj*MiII DostsTh•t•d R¢nr*tsd P4%M414d I1•$t￿rtI￿ Fund F￿nd Unlverslty ￿1V*r1￿¥ Unlv4rslty oIL¢t Yor*6hlr• C•ncqr Y•r*shlr• R4th¢ted Cancer Other T•t•l Funds 2911 Sh4llt•ld Sh￿1111￿ Morq Lll• TtsU¥4 F¥nd Fund At LAprll 2020 8.37%061 38.1￿.￿1 82?38 4201238 3,827,738 137,3J2 56,566,918 12,50W4 63,637 IOJ59 37,527 2,595,089 74.OUO 20.289M86 Expen(thture 165.5111 1SM19.651 1367,1181 1774,2281 (3,£88,50• 11271 I13￿lS,139) 9,201087 (13,8PI b,Id8,230 knvestment iisl (tD5Sé Trarbfeis - Fts￿$ deskJnatOd rlnothe S,689,S041 15.628,?dO 60.K4 At31 Morrli 8k30.207 d7,944,31B 1,56SAOO a￿115.?68 5P37.537 2,$9S.1)$9 211,185 69.029P¥i S6 yoi'kshirecoii¢e.ri'eseoitli.org.uk Consolidated Financial statemènts Char4ty2020 Gon•rRI Fund R¢Jtrtcted P¢¥trktEd 4rsityof Hull ReJtrkl¢d Unlversi¥yof Sh•lfleld Rfjjtrktod other nd At IAprtl 2019 7,7%366 31.449.752 2.463 4.747.9UI 4.187.824 167ffi54 50,812,5dfj IrKom@ 593M5 94077 21,718 7x7 18.71&737 Expond51 (3,5JO,79 (%295,2051 ?J9)1 15bll3811 I36Q￿l 137,9 150J61,S60 Netlnvastmonl (lo5￿5) <5232061 17?,$981 (2MO,8Q4) Tr&ii$fers . Fynd$ dO$Wiated Ilng th¢w•r UI,98OA41 IIM8Q684 At 31Marc51 2020 8,￿$.0$1 3&l35,231 I￿￿2,338 4.209.23t¢ 3,827.n8 IJY,512 96.JI 6$,￿8 15roup 20ZO G•nw*l knd Rertrkled 11r4￿r5ItyoV RwMcteO Qltt•r Tot Fundi Fund Urfwrsltyol L¢*d$ ur4￿r*ityOI Atl Aprll 2019 7,921J27 31M9,752 2,461041 4747,Wl a,187￿1 167,654 SO.937.707 hc¢mo 18,593375 94m7 21318 7,567 18,nI737 EXpend￿re 13,SIO,790) 15,295,205) ($97,190) ($60,381) (360m61 P7))91 aO,362.$61i Not IDvo5tmenl galD5100ssQ5) (1648,367) 177,596) P,7259551 Transfers - Funds dKlgnated d￿ngtheY@¥ UI,980,684) 11,WJh84 At31 Marcl) 4375.06J 38335.231 1862,338 4,209,238 3.827,738 137.312 56,566.918 (Nrtéseontlnuédj . ststementof funds 1I￿￿Vn[estykttd1uno$up10 5yews*trttyd èsdetal￿(s rtote4. (htst￿Y héS&tsod*c￿ètyt0 ha¥o¥onerèireseYvMrefl4ctievelsol qXPgClQLlopoialK>n￿ okyondituroand4nyuiln9ovor and abo roik¢iid lndosiji1a¢￿1vrt￿s Yhis 411grl¥With iii¢¢h&fiiy$str袢gi¢oDiectlv2 gf6peThliiig £IOm peryeoi toochSeYe ks¢hbrltab1cJlmJ. ThÈunlversftyotLo•d5 Endtswrnontlunds, r￿e￿*don31 M¥(h￿l$, Amlnwst*d In&￿15£y*ll poYtfoNtsln LIK GDveinmtt*stock4nd InY4&ttMÈhtgradtCoYpafate Bondswlthmawriiydate5to m*(hthoexpLwddfaw-dtsWn ¢1 t￿¥$$¢¢11t0rtr*styI1Qh411ald. Urthrthgt¢rmsof thfr&yeemqnl.thlslund1sb#ino ustd tosupwria5ye8irese8ithBw4rd ¢Oltte iknFver$llyof Leeds. Th•UnlYtsr%ltyotHull tsrtd u￿v¥￿tY￿1shdf￿￿ Endowmentfund$werèreulwd In Docembei 2016 beoD knY48tldln blnk t+1m41￿¢$INdt￿rMfi¢1¢C0unI5 un￿rthE tsfms•fthe4we¢menis Ihese f4nd6 ortbeln9uspdtO Support Sy¢•rr¢wFchawFdsiothe Uplvtraliyof Null and thé Univer%iiyoI 5helndd. TheFunth ieferred toog iheYtyyk•hli•C4fj¢•rft¢s¢•rth M¢r¢ LV• T• Llv• fvnd•hdlh¢Yorkshk•C4n¢•iRoiearth Sh•ffl4IdP￿n￿fS Fund*+ rescr￿4 lor Ih? Unl¥fridlyol Shtrllk•hl. Ono locuson Yoik5hlY¢CThn¢oi R•8¢•r¢hts$tf*¢gkoblq 11.980214 11,980,1 18,593,375 123.362 1&718,7J7 Résour￿¥*￿plntt•d Expendlture on Funorolslng 2,262.385 3,962 2,26&347 E¥pwdltwe0nCharlts￿*A(l￿l￿l5 6,543,810 I,SSLW4 $P95,214 Totil m￿Ur￿$txPlhde￿ ¢e05.995 lo,3￿,$61 Re8llsedand unrei11$*J Qosya511 Bahi on IDvg¥¢rn¢nl 1558t5 12A48,36 177,5981 12.729,9651 N*tln