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2022-04-05-accounts

Trustees Professor A N Barclay, DPhil
Professor J Errington, FRS, FMedSci
Professor Sir John Walker, FRS, FMedSci
Professor Penny Handford, Dphil
ProfessorARGreen, PhD
Professor Anton van der Merwe
Charity number 309698
Auditor Critchleys Audit LLP
Beaver House
23-38 Hythe Bridge Street
Oxford
OX12EP
Bankers CAF BankLtd
25 King Hill Avenue
West Malling
Kent
ME19 4JQ
Solicitors Knights Solicitors
Midland House
West Way
Oxford
OX20PH
Investment advisors Schroder (Cazenave) Personal Investment Management
1 London Wall Place
London
EC2Y 5AU
OU Endowment Management
27Park End Street
Oxford
OX11HU
BMO Global Asset Management
12 Primrose St
Exchange House
London
EC2A2NY

Page
Trustees report 1 - 3
StatementofTrustees responsibilities 4
Independent auditor's report 5-8
Statementoffinancial activities 9 - 10
Balance sheet 11
Statementofcash flows 12
Notestothe financial statements 13-24

24/10/2022

Current financial year
Unrestricted Endowment
Total
Total
funds funds
2022 2022 2022 2021
Notes £ £ £
£
Income from:
Investment Income 3 3,841,435 3,841,435 3,527,725
Expenditure on:
Investment Management Costs 4 2,149 - 2,149 1,702
Charitable activities
Administrative costs 5 22,401 - 22,401 16,878
Grants Awarded 5 1,880,504 1,880,504 861,920
Total charitable expenditure 1,902,905 1,902,905 878,798
Total resources expended 1,905,054 - 1,905,054 880,500
Net gains/(losses) on investments 9 - 3,438,038 3,438,038 20,226,663
Net incoming resources before transfers 1,936,381 3,438,038 5,374,419 22,873,888
Gross transfers between funds (1,325,161)
1,325,161
Fund balances at 6 April 2021 1,327,949 98,759,051 100,087,000 77,213,112
Fund balancesat5 April 2022 1,939,169 103,522,250 105,461,419 100,087,000

Prior financial year
Unrestricted Endowment Total
funds funds
2021 2021 2021
Notes £ £ £
Income from:
Investment Income 3 3,527,725 3,527,725
-
Expenditure on:
Investment Management Costs 4 1,702 1,702
Charitable activities
Administrative costs 5 16,878 16,878
Grants Awarded 5 861,920 861,920
Total charitable expenditure 878,798 878,798
Total resources expended 880,500 880,500
Net gains/(losses)oninvestments 9 - 20,226,663 20,226,663
Net incoming resources before transfers 2,647,225 20,226,663 22,873,888
Gross transfers between funds {3,142,841)
3,142,841
Net movementinfunds (495,616) 23,369,504 22,873,888
Fund balances at 6 April 2020 1,823,565 75,389,547 77,213,112
Fund balancesat5 April 2021 1,327,949 98,759,051 100,087,000

2022 2021
Notes £
£
£
£
Fixed assets
Investments 10 103,522,250 98,759,051
Current assets
Debtors 12 387,856 373,590
Cash at bank and in hand 4,605,701 3,653,354
4,993,557 4,026,944
Creditors: amounts falling due within
one year 13 (2,723,021) (1,930,329)
Net current assets 2,270,536 2,,096,615
Total assets less current liabilities 105,792,786 100,,855,666
Creditors: amounts falling due after
more than one year 14 (331,367) (768,666)
Net assets 105,461,419 100,,087,000
Capital funds
General endownment funds 16 103,522,250 98,759,051
Income funds
Unrestricted funds 1,939,169 1,327,949
105,461,419 100,,087,000

2022 2021
Notes £
£
£ £
Cash flows from operating activities
Cash absorbed by operations 19 (1,563,927) (917,810)
Investing activities
Purchase of investments (2,000,000) (100,000)
Proceedsondisposalofinvestments 674,839 261,694
Investment income received 3,841,435 3,527,725
--
Net cash generated from investing
activities 2,516,274 3,689,419
Net cash used in financing activities
Net increaseincash and cash equivalents 952,347 2,771,609
Cash and cash equivalents at beginningofyear 3,653,354 881,745
Cash and cash equivalentsatendofyear 4,605,701 3,653,354

Unrestricted Unrestricted
funds funds
2022 2021
£ £
Interest received 5 296
Dividends and interest 3,841,430 3,527,429
3,841,435 3,527,725
--

Unrestricted Unrestricted
funds funds
2022 2021
£ £
Portfolio management 2,149 1,702
2,149 1,702

Grants Grants
Awarded Awarded
2022 2021
£ £
Grants to institutions 1,880,504 861,920
1,880,504 861,920
2022 2021
£ £
DepartmentofBiochemistry - Specific RNAs 69,763
DepartmentofChemistry - Inorganic - Developing Biocatalysis 72,774
OUMNH a - Project IMAGOS 126,979
DepartmentofBiochemistry - Expanding Access 28,160
DepartmentofBiochemistry - Histone in genome stability 32,558
DepartmentofBiochemistry - Cryo-EM structure determination 50,184
DepartmentofBiochemistry - Purchase protein crystal imaging system 69,194
DCHI** - Focused ion beam and scanning electron microscope 366,495
DPAG - Support for year twoofa postdoc 39,906
DepartmentofBiochemistry - Defining the roleofPARPs in the DNA 32,252
DepartmentofPharmacology - Equipment request 11,238
KIR - Establishing Advanced Image Analysis 79,768
OBGA *** - Plant records management 61,561
DepartmentofBiochemistry - Support for outreach events 7,360
DepartmentofBiochemistry-Anultracentrifuge for Biochemistry 40,000
Royal Society - Human Genome Editing 140,000
DepartmentofBiochemistry - Support screening microscope 80,000
DPAG13-Advanced 3D Parkinson's stem cell disease models 143,697
DepartmentofBiochemistry - Phosphorylation sites 30,672
DepartmentofBiochemistry - Regulationofnon-coding RNAs 47,644
MSDO* - Bridging salary scheme 250,000

6 Grants payable (Continued)
HistoryofScience Museum - Collecting COVID 251,989
EM Facility - Research assistant to support projects 152,260
DepartmentofBiochemistry - Target search mechanisms 5,890
DepartmentofBiochemistry - Modelling toolkit for glycans 45,076
DepartmentofBiochemistry - Genotoxic stress on epimutations 93,474
DepartmentofBiochemistry - Site-specific ADP-ribosylation 26,522
OUMNH a - Next generationofEPA Internships 112,969
DepartmentofBiochemistry - New suiteofelectron microscopes 500,000
2,068,882 899,503
KIR Kennedy InstituteofRheumathology
*Medical Sciences Division Oxford
** Dorothy Crowfoot Hodgkin Institute
*** Oxford Botanic Garden & Arboretum
#DepartmentofPlant Sciences
a Oxford University MuseumofNatural History
~DepartmentofPhysiology, Anatomy and Genetics
WIMM Weatherall InstituteofMolecular Medicine
Adjustments to grants duringtheyearwereasfollows: 2022 2021
£ £
DepartmentofBiochemistry - Expanding user access to NMR - (30,306) (30,306)
DepartmentofZoology - Support - (7, 168) (7,168)
DepartmentofBiochemistry - Post doctoral support(x2)- (109) (109)
DepartmentofBiochemistry - Nanobodies etc. facility (10) - (10)
OUMNH a - Summer internship programme (26,556) - (26,556)
Linacre College - Widening participation scholarships (1,052) - (1,052)
Chemistry - Inorganic - Energized NanoconfinementofEnzymes (2,808) - (2,808)
DepartmentofBiochemistry - Histone ADP-ribosylation (1) - (1)
DepartmentofBiochemistry - Cryo-EM structure determination (13,926) - (13,926)
DepartmentofBiochemistry - Defining the role PARPsinDNA Repair (327) - (327)
DPAG~-Advanced3D Parkinson's stem cell disease models (143,697) - (143,697)
DepartmentofBiochemistry-Target search mechanisms for bZIP (1) . - . (1)
--
(188,378) (37,583)
1,880,504 861,920

2022 2021
Number Number

Endowment Endowment
funds funds
general general
2022 2021
£ £
3,438,038 20,226,663

Investments
£
Cost or valuation
At 6 April 2021 98,759,051
Additions 2,000,000
Valuation changes 3,438,038
Disposals (674,839)
At 5 April 2022 103,522,250
Carrying amount
At 05 April 2022 103,522,250
At 05 April 2021 98,759,051
11 Financial instruments 2022 2021
£ £
Carrying amountoffinancial assets
Instruments measured at fair value through profit or loss 103,522,250 98,759,051
12 Debtors
2022 2021
Amounts falling due within one year: £ £
Other debtors 387,856 373,590

13 Creditors: amounts falling due within one year
2022 2021
£ £
Grants payable 2,717,021 1,924,891
Accruals 6,000 5,438
2,723,021 1,930,329
14 Creditors: amounts falling due after more thanoneyear
2022 2021
£ £
Grants payable 331,367 768,666

No Grant 8/fwd2021
N
ew 2021/22 Ad justments Pa id 2020/21
C
/fwd 2022
266 DepartmentofBiochemistry - Contribution to facility for nanobodies etc. (50,000) - 10 49,990
277 DepartmentofExperimental Psychology - retinal imaging for the eye (30,000) 30,000
279 DepartmentofBiochemistry - Confocal microscopy systems (75,000) - 75,000
294
298
OUMNH - Summer internship programme
DepartmentofChemistry - Chemical Biology Facility
(48,775)
(500,000)
26,556 500,000 (22,219)
CF 320
CF 332
King Edward School - Bursaries and refurbishment
OUM NH - public engagement with research - First Animals exhibition
(400,000)
(92,500)
-
-
100,000
92,500
(300,000)
CF 334
CF 335
DepartmentofPlant Sciences - Shaking incubator system
DepartmentofPlant Sciences - Field emission scanning electron scope
(16,919)
(159,166)
- 159,166 (16,919)
CF 336 WIMM- Establishing an imaging mass cyometry platform (50,000) 50,000
CF 338
CF341
CF 342
Linacre College - Widening participation scholarships
DepartmentofBiochemistry - Specific RNAs
DepartmentofChemistry - Inorganic - Developing biocatalysis
(386,175)
(69,763)
(72,774)
1,052
2,808
15,000
69,966
(370,123)
(69,763)
CF 343
CF 344
CF 345
OUMNH a - Project IMAGOS
DepartmentofBiochemistry - Expanding access
DepartmentofBiochemistry - Histoneingenome stability
(123,736)
(28,160)
(32,558)
1 40,962
32,557
(82,774)
(28,160)
CF 346 DepartmentofBiochemistry - Cryo-EM structure determination (39,839) 3,581 36,258
CF 346e DepartmentofBiochemistry - Cryo-EM structure determination (10,345) 10,345
CF 349 DepartmentofBiochemistry - Purchase protein crystal imaging system (69,194) 69,194
CF351
CF 352
DCHI** - Focused ion beam and scanning electron microscope
DPAG - Support for year twoofa postdoc
(366,495)
(39,906)
1 39,905 (366,495)
CF 354 DepartmentofBiochemistry - Defining the roleofPARPsinthe DNA (32,252) 327 31,925
CF 356
CF 357
CF 358
KIR - Establishing Advanced Image Analysis
OBGA *** - Plant records management
DepartmentofBiochemistry - Support for outreach events
(79,768)
(61,561)
(7,360)
7,360 (79,768)
(61,561)
CF 359 DepartmentofBiochemistry-Anultracentrifuge for biochemistry (40,000) 40,000
CF 360
CF361
CF 362
Royal Society - Human genome editing
DepartmentofBiochemistry - Support screening microscope
DPAGJ3-Advanced30Parkinson's stem cell disease models
(140,000)
(80,000)
(143,697)
1
143,697
79,999 (140,000)

15 Reconciliationofmovement in grants during the year (Continued)
CF 363 DepartmentofBiochemistry - Phosphorylation sites (30,672) (30,672)
CF 364 DepartmentofBiochemistry - Regulationofnon-coding RNAs (47,644) (47,644)
CF 365 MSDO - Bridging salary scheme (250,000) (250,000)
CF 366 HistoryofScience Museum - Collecting COVID (251,989) (251,989)
CF 367 EM Facility - Research assistant to support projects (152,260) (152,260)
CF 368 DepartmentofBiochemistry - Target search mechanisms for bZIP (5,890) 5,889
CF 369 DepartmentofBiochemistry - Modelling toolkit for glycans (45,076) (45,076)
CF 370 DepartmentofBiochemistry - Genotoxic stress on epimutations (93,474) (93,474)
CF 371 DepartmentofBiochemistry - Site-specific ADP-ribosylation (26,522) (26,522)
CF 372 OUMNH a - Next generationofEPA Internships (112,969) (112,969)
CF 374 EM Facility - Newsuiteofelecton microscopes (500,000) (500,000)
(2,693,557) (2,068,882) 188,380 1,525,671 (3,048,388)

Balance at Transfers Revaluations Balance at Transfers Revaluations Balance at
6April 2020 gains and 6April2021 gains and 5April 2022
losses losses
£ £ £ £ £ £ £
75,389,547 3,142,841 20,226,663 98,759,051 1,325,161 3,438,038 103,522,250
75,389,547 3,142,841 20,226,663 98,759,051 1,325,161 3,438,038 103,522,250

Analysisofnet assets b etween funds
Unrestricted Endowment Total Unrestricted Endowment Total
funds funds funds funds
2022 2022 2022 2021 2021 2021
£ £ £ £ £ £
Fund balances at 5
April 2022 are
representedby:
Investments - 103,522,250 103,522,250 - 98,759,051 98,,759,051
Current assets/(liabilities) 2,270,536 2,270,536 2,096,615 2,096,615
Long term liabilities (331,367) (331,367) (768,666) (768,666)
1,939,169 103,522,250 105,461,419 1,327,949 98,759,051 100,087,000

19 Cash generated from operations 2022 2021
£ £
Surplus for the year 5,374,419 22,.873,888
Adjustments for:
Investment income recognisedinstatementoffinancial activities {3,841,435) (3,527,725)
Gainondisposalofinvestments (3,438,038) (20,226,663)
Movements in working capital:
(Increase)indebtors (14,266) (373,590)
Increaseincreditors 355,393 336,280
--
Cash absorbed by operations {1,563,927) (917,810)