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2022-06-30-accounts

Juvenile Diabetes Research Foundation Limited

Annual Report and Financial Statements

30 June 2022

Company Limited by Guarantee Registration Number 02071638 (England and Wales) Charity Registration Number 295716 (England) and SC040123 (Scotland)

Contents

Reports
report 3
Reference and administrative details 19
Independent auditor
s report		 21
Financial Statements
Consolidated statement of financial
activities 26
Balance sheets 27
Consolidated statement of cash flows 28
Principal accounting policies 29
Notes to the financial statements 34

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Juvenile Diabetes Research Foundation Limited

Report Year ended 30 June 2022

The Directors present their report, together with the audited financial statements of Juvenile Diabetes Research Foundation Limited , for the year ended 30 June 2022.

This report has been prepared in accordance with Part 8 of the Charities Act 2011 and the Charities Accounts (Scotland) Regulations 2006 (as amended) and serves as the report of the Directors for the purposes of the Companies Act 2006.

The financial statements have been prepared in accordance with the accounting policies set out on pages 28 to 32 applicable laws and Accounting and Reporting by Charities: Statement of Recommended Practice applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the United Kingdom and Republic of Ireland (FRS 102), effective from accounting periods commencing 1 January 2015 or later.

About JDRF: a global mission to cure type 1 diabetes

JDRF in the UK is proud to be a part of a global network of independent and coordinated organisations working towards the same vision: a world without type 1 diabetes. There are JDRF affiliates in the USA, UK, Canada, Australia, Netherlands and Israel.

administered by JDRF in the USA to invest in the most promising research worldwide.

international mission is to improve lives today and tomorrow by accelerating lifechanging breakthroughs to cure, prevent and treat type 1 diabetes and its complications.

Our mission in the UK

r mission of eradicating type 1 diabetes and its effects for people in the UK we:

Drive research to cure, treat and prevent type 1

We are committed to increasing funding for world-class international type 1 diabetes research, with UK research teams at the forefront, and building research communities across autoimmune conditions

Accelerate access to type 1 treatment technologies and medicines

We are committed to influencing greater NHS access to type 1 technology and treatments and involving people with type 1 in research and regulatory approval

Support people living with type 1

We are committed to building connected communities to support people living with type 1 and being a trusted source of information

Juvenile Diabetes Research Foundation Limited 3

Report Year ended 30 June 2022

Chair & CEO Foreword

This last year for JDRF is defined by an organisational step change in progress and mission delivery. We have brokered a new partnership and unprecedented levels of funding for type 1 research in the UK. We helped changed regulatory guidelines so that people with type 1 diabetes will now start to have universal access and choice of Flash or Continuous Glucose Monitors across Great Britain on the NHS. And we have delivered this against the backdrop and challenge of the pandemic, while maintaining our income.

In April 2022 we were delighted to launch the £50 million Types 1 Diabetes Grand Challenge, a ground-breaking partnership between JDRF, the Steve Morgan Foundation (SMF) and Diabetes UK to accelerate the route to cures for type 1 over the next five years. We are grateful to our long-term major donors, Steve and Sally Morgan, for the £50 million investment, the largest ever single philanthropic gift in the UK for type 1 diabetes research.

We were also delighted to see new access to type 1 technology on the NHS, with our longterm policy work playing a pivotal role in changing regulatory guidance. Everyone with type 1 in England and Wales will now have access to either Continuous Glucose Monitors or Flash Glucose Monitoring.

Such access to digital health technology will help prevent life threatening blood glucose fluctuations, reduce the long term risk of diabetes-related complications including kidney failure and sight loss, thereby lifting the mental burden of this relentless condition. Our advocacy work also helped ensure that hybrid closed loop systems (also known as the artificial pancreas) were recommended for treatment on the NHS in Scotland.

We, like everyone else, continue to live with the effects of the pandemic. This last year we published a report which investigated the impact of the pandemic on people living with COVID and the inevitable disruption to health services. The report and its recommendations were warmly welcomed by parliamentarians, NHS policy and service delivery leaders. In the meantime, our information resources continue to be a vital support for people navigating type 1 and its effects through the pandemic.

Despite all the challenges of the last three years, we are proud to have maintained our income, through the generosity of our donors, as well as our trading partnerships and by securing both charitable and government grants. It has been far from easy, given the last -person fundraising activities, but we are delighted that we have delivered robust income and are confident we will grow sustainable income next year.

JDRF is rightly ambitious in mission and income generation and matches organisational ambition with sound governance, effective programme delivery and efficient use of organisational resource.

David McTurk Karen Addington Chair Chief Executive Officer

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Report Year ended 30 June 2022

OUR THREE-YEAR STRATEGY: FY21-23

-year FY21-23 strategy, which furthers our vision of a world without type 1 diabetes. The strategy embeds a greater focus on mission outcomes and organisational effectiveness. This report outlines our progress against the second year of this strategy.

1. FY22 mission goal - driving research

Under JDRF progress into autoimmune research during FY22. The CIR consortium and the Lorna and Yuti Chernajovsky Biomedical Research Foundation joined forces to fund ten translational projects in autoimmunity worth just under £1 million in total. Each project is relevant to at least two autoimmune conditions and will bring together different research teams. The programme and funding seek to break down research silos between autoimmune conditions. The results of the work undertaken in these projects will be presented to the funders in Q3 2023.

During the year JDRF established a new partnership with MQ Mental Health Research to support research to develop psychosocial and behavioural health interventions for people with type 1 diabetes. The partnership has led to the launch of a new international fellowship funding opportunity, and the partnership is increasing the visibility of JDRF in the wider psychosocial field at a national and international level.

We have developed new web resources to encourage more people with type 1 to get involved in research activities. The take part in research page presents opportunities for people with type 1 diabetes to be involved in research projects. 17 new opportunities were presented during FY22. In addition, we have developed new resources for the research community to ensure researchers have a good understanding of different models of participation, engagement and involvement of people with type 1 in research and how JDRF can support these activities.

Juvenile Diabetes Research Foundation Limited

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OUR THREE-YEAR STRATEGY: FY21-23 (continued)

1. FY22 mission goal - driving research (continued)

In the last financial year JDRF delivered £2 million of charitable funding to support the global international research programme. Some of the most promising outcomes of the programme are summarised below.

Pharmaceutical company Vertex announced early results from its clinical trial of VX-880, a treatment that replaces lost beta cells so that people with type 1 can produce their own insulin again. One patient needed 91% less daily insulin 90 days after receiving just half the target dose. One side effect however is that immunosuppressant drugs are required to prevent the immune system from destroying the new beta cells. Despite this known sideeffect, these results are a huge step forward in the search for a cure for type 1 diabetes. The research, spearheaded by Professor Doug Melton at Harvard University, was made cells from stem cells. JDRF had also pre company Semma, subsequently acquired by Vertex, through the T1D Fund.

registered in the USA is an innovative way of maximising significant philanthropic gifts from major international and UK donors in order to catalyse private sector investment in type 1 diabetes research and development. By investing in promising venture equity investment which in turn leverages significant capital investment from the recycled back into the Fund to provide seed finance for further promising research pharmaceutical company Vertex has enabled research into beta cells to be expanded with exceptional trial results. Since its inception in 2016 to June 30, 2022, the Fund has invested over £67M ($80M) in 31 companies, attracted over £490M ($580M) of private investment and generated nearly £47M ($55M) in returns that will be reinvested.

2. FY22 Accelerating access to treatments

In FY22, JDRF published a report on the impact of the Covid-19 pandemic on NHS type 1 diabetes services. The report, Covid and Beyond: Confronting the Unequal Access to Type 1 Diabetes Healthcare, highlights the withdrawal of NHS services for people with type 1 and the increasing unequal access to care. The report found that nearly two thirds of adults with type 1 diabetes had been unable to access their normal levels of NHS care during the height of the pandemic and that nearly fifty per cent of those surveyed felt there would be an enduring negative impact on their health. We made several recommendations on how to rebuild services after the disruption of the pandemic, including increased access to type 1 technologies, providing choice by offering in-person, telephone or virtual appointments, the need for improved communication from the NHS in times of crisis, and including people with type 1 in service design and delivery. These recommendations were well received and have formed the basis of discussions with NHS diabetes and key stakeholders about the future of type 1 diabetes care.

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Report Year ended 30 June 2022

OUR THREE-YEAR STRATEGY: FY21-23 (continued)

2. FY22 Accelerating access to treatments (continued) In March 2022, the National Institute for Health and Care Excellence (NICE) updated its guidance on type 1 diabetes specialty adviser has been fundamental in driving the change in regulatory guidance, supported by patient advocacy organisations such as JDRF. The new guidance recommends that people with type 1 diabetes in England and Wales are offered a choice of Continuing Glucose Monitoring (CGM) or Flash Glucose Monitoring and that the preexisting clinical criteria for access be removed. This is a significant advance in widening access to technology and comes following campaigning over many years from JDRF. As for clinicians to actively monitor and address inequalities in uptake of CGM, which we know affects those from hardly reached communities. People with type 1 diabetes in Scotland already have similar access. There is however still an urgent need for people in Northern Ireland to secure equitable access.

In April 2022, JDRF published its report, Research to Reality, which set out a new way of report calls for a new framework which prioritises the needs of people with type 1 across research, clinical and regulatory processes: these priorities are a long life in good health, increased physical and mental wellbeing, improved time in range, reduced risk of complications and reduced risk of life-threatening fluctuations in blood glucose levels. The report also calls for more focus and funding on curative and preventative treatment. The report was warmly welcomed by a range of diabetes stakeholders who fully accept the recommendations and have pledged to work with JDRF in taking these forward.

3. FY22 Providing information and support for people type 1

JDRF has continued to provide support for people with type 1 through answering individual enquiries, hosting events and providing trusted information and support resources.

Our new Type 1 and Disordered Eating (T1DE) hub on the JDRF website was coproduced with people living with type 1 and healthcare professionals. It contains information, risk factors, signs and symptoms, complications and important signposting, underpinned by videos of lived experience stories. JDRF has also been advising the Coronation Street script writers on a T1DE storyline to ensure accuracy.

In FY22 we distributed over 46,000 printed and digital information support resources for people with type 1 and healthcare professionals. We have seen excellent uptake in our digital resources, including our schools e-learning module which has been accessed by 23,663 users.

In FY22 JDRF began an organisation wide project to address health inequality, improve k includes a review of our existing information and support content and creating new resources with a focus on specific issues and audiences. This includes the increase of animations to simplify information and more sub-titled video from diverse first-person perspectives. We

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OUR THREE-YEAR STRATEGY: FY21-23 (continued)

3. FY22 Providing information and support for people type 1 (continued)

have deepened partnerships with NHS groups and other organisations to increase our engagement with diverse community groups. Throughout FY22 we have increased diversity in the lived experience content on our website and publications, with a quarter of case studies now representing diverse experience.

Seven community events were held across the UK in FY22, which have focused on type 1 management, type 1 technology, peer support and exercise with hundreds of participants. We have run four virtual events which continue to be popular post-pandemic with over one thousand registrations. We have additionally launched a new series of type 1 technology events for people to find out more about existing and new type 1 medical technology now available on the NHS to help manage type 1.

JDRF, NHS England and Diabetes UK have scoped an England-wide programme of peer support for people with type 1, funded and delivered through the NHS. JDRF has been responsible for the shaping of definition and principles with Diabetes UK.

Looking Forward: The final year of our three-year strategy

FY23 is the final year of our current three-year strategy. We will maintain our focus on our three mission goals and focus on growing income and impact.

Drive research to develop cures and improve lives for people with type 1

As partner in the Steve Morgan Foundation Type 1 Diabetes Grand Challenge, we will lead the funding of global research into developing new forms of personalised and responsive insulins. We will grow the Connect Immune Research consortium with additional medical research charity partners, while we build on the £1 million Chernajovksy Foundation grant to deliver insight into the common causes and potential treatments of autoimmune conditions.

We will work to secure regulatory approval to make the hybrid closed loop artificial pancreas available on the NHS to anyone with type 1 who would benefit from this technology. We will continue our work to widen access to insulin pump therapies and continuous glucose monitoring on the NHS. We will focus on addressing regional and socio-economic health inequalities in type 1 diabetes treatment and care, working with policy makers, stakeholders and people with type 1.

Information and Support

We will build on the work we started in FY22 to reach and support people living with type 1 from more disadvantaged communities. This work will focus on co-production of resources, making content accessible and best practice in providing information through events. We will help deliver new forms of peer support both via the NHS and JDRF to help people with type 1 build the skills, knowledge and confidence by being connected with each other, learning and drawing support from each other to help to live well with type 1.

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Report Year ended 30 June 2022

OUR THREE-YEAR STRATEGY: FY21-23 (continued)

Looking Forward: The final year of our three-year strategy (continued)

Resources and Infrastructure

We will deliver on these mission goals by growing our income and increasing our return on investment. We will increase our organisational effectiveness with better data management and integration of data with a new website and database. We will expand our focus on equality, diversity and inclusion across our recruitment and working practices, our research development and policy influencing. Finally, we will deliver greater impact by engaging with more beneficiaries, through improved brand awareness, customer support and information services.

FY22 FINANCIAL REVIEW

Summary

Early in the pandemic JDRF successfully applied for emergency Covid funding from statutory and philanthropic sources which kept income at a stable level. This stability continued in FY22, when greater fundraised income largely compensated for reduced emergency funding during the year. Some activities were necessarily curtailed during the pandemic, with related cost savings as a result. This included a slightly slimmed down and, in some cases, refocused staffing structure in line with changing circumstances.

Our ability to keep income stable despite difficult external circumstances allowed previously low levels of reserves to be build up in the short term. This guards against possible impacts of the developing economic uncertainty in the UK and elsewhere, and risks to future income generation. Free reserves at the end of FY22 were three months of at £3.5m (FY21: £3.9m), as we aimed to keep cure focused research funding and support for people with type 1 as high as possible in a year in which we had to deal with considerable uncertainty.

Income generation

Income of £5.9m was a little lower than the previous year (FY21: £6.4m). Fundraised income grew by £1.3m, which largely compensated for the £1.75m reduction in two different grants from the Steve Morgan Foundation (the DCMS supported Covid related Community Match Challenge (CMC) grant, and a separate multi year grant exclusively towards medical research).

Expenditure - research and other charitable activities

With a £1m a year research grant from the Steve Morgan Foundation concluding the previous year we expected a drop in the value of research advocacy and funding, but were able to limit this to less than £400K (FY22: £2.4m versus FY21: £2.8m). UK and global research achievements during the year are described on pages five to nine.

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Report Year ended 30 June 2022

FY22 FINANCIAL REVIEW (continued)

Expenditure - research and other charitable activities (continued)

JDRF's support and awareness costs grew slightly to £1.07m (FY21: £1.05m), as we continued to provide up-to-date information to people with type 1 as the pandemic progressed. Details of the activities and achievements of our work in these areas are described on pages five to nine.

Expenditure costs of raising funds

In FY22 the cost of raising funds grew by 18 percent to £2.0m (FY21: £1.7m). However, this resulted in growth in fundraised income of 28 percent, so represents continued increased efficiency in this key area of operations.

JDRF Trading Limited

These accounts consolidate the income, costs, assets and liabilities of JDRF Trading Limited with those of JDRF. This small wholly owned trading subsidiary enables JDRF to take advantage of opportunities to develop revenue from the corporate sector through sponsorship of certain events and activities for people with type 1. The company produces and are summarised in note 11 to the following accounts. Following two years of significant and operating profit for the year (gift aided in full to JDRF) also increased to £274,000 (FY21: £228,000).

Balance sheet for the charitable group

Cash and short-term deposits at 30 June 2022 totalled £2.48m (FY21: £2.14m). Cash is held in instant access and short-term deposit accounts that allow the best rate of interest at the level of risk deemed acceptable.

Debtors at the year-end were £615,000 (FY21: £424,000), of which £315,000 related to accrued income (FY21: £129,000). Of the total year end debtors figure, 98 percent had been received by November, and the outstanding balance is not considered at risk. Creditors were £554,000 (FY21: £438,000).

Funds

Restricted funds grew during FY22 from £407,000 to £77,000, as some restricted funds from the CMC grant were received before being spent on the designated projects. All CMC funds will be spent in full during FY23.

Unrestricted funds increased from £1.82m to £1.85m. The impact of this change on

JDRF finances FY23 and beyond

ected to return closer to pre-pandemic levels in FY23, with emergency Covid funding dropping to low levels in its final year. In addition, the SMF Type 1 Grand Challenge will start operation during FY23, and run until FY28, with its first

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Report Year ended 30 June 2022

FY22 FINANCIAL REVIEW (continued)

JDRF finances FY23 and beyond

over this time and advance the search for cures and treatments for type 1. While income will increase considerably, the Grand Challenge income will be fully accounted for by onward research grants and related costs, and not in any other way benefit JDRF financially.

GOVERNANCE INFORMATION

Public benefit and grant making policy

The Directors have taken account of the Charity Commission's guidance on public benefit in reviewing JDRF's aims and objectives and in planning future activities. JDRF aims to global research department provides details of the UK grant payments due on a monthly basis and JDRF pays those funded by restricted grants and donations and as much of the other grants as available funds and our reserves policies allow.

Activity in Scotland

JDRF has staff based in different parts of Scotland, supported by an active and capable volunteer group. We are well supported by the public across Scotland, which raises funds the year. In line with its goal of funding the best research wherever it is taking place in the world, JDRF funds type 1 diabetes research in Scotland and during FY22 funded projects at the Universities of Edinburgh and Dundee.

JDRF fundraising statement

Almost all our work driving the search to cure, treat and prevent type 1 diabetes, and all the work we do to help and support people affected by type 1 diabetes, is made possible hed resilience during and after the Covid pandemic. We receive no direct government funding towards our research. Fundraising is vital for our work, and we are passionate about building strong, long-lasting relationships with our supporters through considerate, ethical fundraising and supporter care.

We use a range of recognised methods to raise funds. This includes working with trusts and foundations, philanthropists, businesses, schools and clubs, and individuals who take part in our fundraising events, run fundraising events of their own, respond to our appeals or donate directly to us. Our fundraising team leads on this work, with almost all of the fundraising activity being managed in-house. It is supported from time to time by a professional telephone fundraising agency whose small team we have worked closely with over the last seven years, and who we engage to speak with a limited number of our supporters on our behalf.

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Report Year ended 30 June 2022

GOVERNANCE INFORMATION (continued)

JDRF fundraising statement (continued)

As we resume our event fundraising post-pandemic, we are careful to adhere to government guidance on Covid-19 and we review this as part of our risk assessment when planning and holding in-person events. Ahead of physical events, we provide our supporters with relevant information that they may wish to consider such as limited attendee numbers and ventilation, and we encourage them to follow a short list of relevant guidelines to help keep both our staff and supporters safe.

Fundraising on our behalf

When we appoint a fundraising agency, we ensure their work on our behalf is both effective and aligned with our values and responsibilities. The agency that we use is a corporate member of the Institute of Fundraising, is registered as a commercial supplier with the Fundraising Regulator, and complies with the codes of practice of both organisations. In line with recommendations from the Fundraising Regulator we train agency fundraisers according to our standards and expectations and we monitor calls made on our behalf on a regular basis.

Our Supporter Promise

We developed our supporter promise to make sure that everyone who comes into contact with us is respected and valued, and to let them know that their data is safe and secure with us. Our supporter promise can be found at https://jdrf.org.uk/getinvolved/give/donation-v2/our-supporter-promise. To date we have received three suppression requests from the Fundraising Preference Service. All three requests were resolved in line with Fundraising Preference Service rules and our own internal procedures.

Further fundraising regulation

We are registered with the Fundraising Regulator and adhere to its code of Fundraising Practice. JDRF is a member of the Institute of Fundraising. We are committed to best practice in fundraising and to complying with all statutory regulations, including the Charities Act 2016, the General Data Protection Regulation, the Privacy and Electronic Communications Regulations 2003 and the Mailing and Telephone Preference Services.

Complaints

During FY22, we received five complaints about our fundraising activities, none of which were related to intrusion of privacy, unreasonable persistence or pressure to give. All complaints were resolved satisfactorily, with none being referred to external regulatory bodies.

Protecting Vulnerable Supporters

Our supporters are at the heart of everything we do, and we understand that protecting those that may be in vulnerable positions is crucial for safe and effective fundraising. Our external fundraisers receive training in recognising vulnerable people. We take steps to privacy, including not making telemarketing calls during unsociable hours and limiting the

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GOVERNANCE INFORMATION (continued)

Protecting Vulnerable Supporters (continued)

number of times we call unanswered numbers. We limit the number of times we make financial requests for support in a single call to avoid applying undue pressure. We monitor and limit the number of mail, email and telephone communications we send to supporters asking for their financial support, ensuring requests are not unreasonably persistent.

Financial policies and activities

Reserves policy

The Board has adopted a reserves policy which is designed to assist with managing reasonable levels of risk, making funds available for future activities and providing for cash flow movements, while maximising the flow of funds to research.

The Board reviews its reserves policy with reference to Charity Commission guidelines every two years. The current policy takes a range of historical costs and movements on income, and aggregates these to establish high and low points for cash balances and free reserve levels. On this basis the Board expects JDRF under normal circumstances to hold free reserves between £1m and £1.5m. JDRF received significant levels of support during FY21, which was intended to provide support through to 2023. As a result our free reserves (unrestricted funds minus fixed assets) have increased in the short-term, standing at £1.8m at the year end. Reserves are expected to return to the policy range in the short to medium term.

Risk management and mitigation

The Board monitors the principal business and control risks to JDRF, within a control framework. The risk assessment register is reviewed at least twice a year by senior management and updated accordingly. Following a review, the format and contents of the register have been updated during the year. Severity and likelihood definitions have been added, and the treatment of risk outcome scores identified. Pre and post-mitigation scorings have been added to add clarity and dynamism. Strategies and timelines have been agreed for the management and limitation of identified risks, the most important of which have been reviewed by the Audit and Risk Committee and the Board.

At present JDRF has no red risks (risk score 15+) and three amber risks (risk score 9-12) out of a possible total of 25. The SMF funded Grand Challenges programme brings complexity and challenge in several areas, though with significant mitigations in place. Post pandemic there is a risk of a slowdown in funding priorities for type 1 research in the profile with the type 1 research community, and other research funders in the UK. Other funding partnerships are being developed to build stronger relationships with a range of research funders and related key stakeholders. The remaining risk relates to the potential impact on a charity the size of JDRF should several key staff leave over a short period of time. JDRF has policies and good practice aimed at staff retention and talent management, and reviews succession planning for critical roles on a regular basis.

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GOVERNANCE INFORMATION (continued)

Financial controls review

In the autumn of 2021, the Audit and Risk Committee and the Board reviewed the updated thorough exercise concluded to its activities and that risks are mitigated appropriately and proportionately.

STRUCTURE, GOVERNANCE AND MANAGEMENT

JDRF is a charitable company limited by guarantee incorporated on 6 November 1986 and registered as a charity on 14 May 1987. The objects and powers of the company are set out in, and governed by, its articles of association. New articles of association were adopted in 2017, reflecting up-to-date law and practice.

JDRF is governed by a Board of Directors, the members of which are also the trustees of the charity for the purposes of charity law, which meets at least five times a year. The Board sets the strategic goals of JDRF, reviews the pursuit of charitable objectives, establishes policy, and monitors financial status and compliance with legal requirements. The Chief Executive assists the Board in these activities and together with the staff is running of JDRF.

The Board of Directors has established two Sub-Committees to assist in the efficient execution of its responsibilities and duties: the Succession and Development Committee and the Audit and Risk Committee. In addition, the Board has informal progress meetings between the quarterly Board business meetings at which there is the opportunity to hear updates on current issues or have fuller discussions of wider matters of interest.

The Succession and Development Committee (made up of at least three current or former Directors and an independent recruitment expert) meets as needed and is responsible for identifying and recruiting new Directors and ensuring retention and development of senior level volunteers. During the year the Committee carried out an open recruitment process for the Chair who retires from the Board in December 2022. After interviewing several candidates the current Vice Chair, Phil Aird-Mash, was appointed by the Board to the role.

The Audit and Risk Committee is responsible for JDRF's compliance with statutory reporting, managing the relationship with the external auditor, reviewing the draft accounts and accompanying report, JDRF's risk management and a range of financial controls and processes. This Committee is made up of the Treasurer and at least one other Director, is attended by the Director of Finance and Resources and Head of Finance and meets two or three times a year.

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STRUCTURE, GOVERNANCE AND MANAGEMENT (continued)

Appointment of Directors

All potential Directors of JDRF go through a nomination process before they join the Board. This is within the remit of the Succession and Development Committee which has the goal of identifying and meeting individuals who have the necessary skills, experience and Directors are appointed by the Board and serve an initial term of three years but may be reappointed for a further term of three years.

Induction of new Directors

Prior to appointment, potential Directors meet our Chief Executive, Chairman, and representatives from the Succession and Development Committee to discuss the work of a Board Director in depth and the expectations and responsibilities of the role. They are given an overview of organisational history, current activities and strategy. Following their appointment to the Board, new Directors have induction meetings with the senior management team and are given relevant key documentation.

Training of Directors

Collective and individual training on issues of strategy and governance is offered to Directors.

Remuneration of key management personnel

The executive team consists of the Chief Executive and five Director of Department roles: Research Partnerships, Policy and Communications, Fundraising, Finance and Resources and People and Operations, as detailed in the reference section on page 18.

JDRF is committed to being open about the work that we do to achieve our mission. skilled staff we need to create a world without type 1 diabetes. All JDRF staff, including the senior management team, are normally eligible for an annual cost of living pay award, and a progression pay scheme that rewards staff who make a significant contribution to JDRF. The amount paid to senior staff reflects the market for jobs in comparable organisations, the performance of the organisation and the skills and contribution of the against the market by a specialist pay and reward consultancy, and agreed by the three board officers.

Volunteers

Volunteers play a vital role at JDRF. All Board Directors and advisors from the scientific community give their time free of charge. We launched the Insight and Experience Panel of 140 people with lived experience with type 1 to support aspects of the work of JDRF. The panel has assisted with providing case studies for NICE consultation responses and such as how JDRF can contribute insight to international initiatives like building consensus on Patient Reported Outcomes among the international research community. In FY22 over 500 individuals volunteered to support JDRF, and we are extremely grateful to all of these dedicated supporters.

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STATEMENT

The Directors are responsible for preparing the trustees' report and the financial statements in accordance with applicable law and United Kingdom Accounting Standards (United Kingdom Generally Accepted Accounting Practice).

Company law requires the Directors to prepare financial statements for each financial year which give a true and fair view of the state of affairs of the company and the group and of the incoming resources and application of resources, including the income and expenditure, of the group for that period.

In preparing these financial statements, the Directors are required to:

The Directors are responsible for keeping proper accounting records that disclose with reasonable accuracy at any time the financial position of the company and enable them to ensure that the financial statements comply with the Companies Act 2006, the Charities and Trustee Investment (Scotland) Act 2005 and the Charities Accounts (Scotland) Regulations 2006. They are also responsible for safeguarding the assets of the company and the group and hence for taking reasonable steps for the prevention and detection of fraud and other irregularities.

Each of the Directors confirms that:

This confirmation is given and should be interpreted in accordance with the provisions of s418 of the Companies Act 2006.

Members of the company guarantee to contribute an amount not exceeding £10 to the assets of the company in the event of winding up. The total number of guarantees at 30 June 2020 was 9. The Directors have no beneficial interest in the company but as members are entitled to voting rights.

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AUDITORS

Buzzacott LLP was reappointed auditor by the Board for the year ended 30 June 2023 and has expressed its willingness to act in that capacity.

Approved by the Directors on 12 December 2022 and signed on their behalf by

David McTurk Chair

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Reference and administrative details

President
Directors
Company Secretary
Executive management team
Chief Executive
Director of Fundraising & Engagement
Director of Research Partnerships
Director of Policy and Communications
Director of Finance and Resources
Director of People and Operations
Registered office
Telephone
Website
Social media		 Her Royal Highness The Duchess of Cornwall
The Directors, who are also trustees under
charity law, who served during the year up to the
date of this report were as follows:
Phil Aird-Mash (Vice Chair)
Barrie Brien
Jared Chebib (Treasurer)
Christina Croft
Wilson Leech
Per Lundin
James Lurie
David McTurk (Chair)
Jonathan Taylor
Karen Addington
Mike Straney (to September 2022)
Terence Lovell (from November 2022)
Rachel Connor
Hilary Nathan
Jonathan Taylor
Hayley Anderson
17/18 Angel Gate
City Road
London
EC1V 2PT
T: 020 7713 2030
F: 020 7713 2031
E: info@jdrf.org.uk
www.jdrf.org.uk
@JDRFUK/https://twitter.com/jdrfuk
@JDRFUK/https://www.facebook.com/JDRFU
K/JDRFUK
JDRFUK/https://www.linkedin.com/company/jdr
f-UK
JDRFUK/https://www.instagram.com/jdrfuk/

Juvenile Diabetes Research Foundation Limited 18

Reference and administrative details

Company registration number 02071638 (England and Wales) Charity registration number 295716 (England and Wales) SC040123 (Scotland) National and regional offices JDRF Scotland: Aberdeen Office T: Aberdeen: 01224 248 677 T: Central Scotland: 07790 572188 E : scotland@jdrf.org.uk Auditor Buzzacott LLP 130 Wood Street London EC2V 6DL Bankers Barclays Bank plc Marble Arch Corporate Banking Group PO Box 32016 London NW1 2ZH

Juvenile Diabetes Research Foundation Limited 19

report 30 June 2022

Juvenile Diabetes Research

Foundation Limited

Opinion

We have audited the financial statements of Juvenile Diabetes Research Foundation Limited for the year ended 30 June 2022 which comprise the consolidated statement of financial activities, group and charitable parent company balance sheets and consolidated statement of cash flows and notes to the financial statements, including a summary of significant accounting policies. The financial reporting framework that has been applied in their preparation is applicable law and United Reporting Standard applicable in the UK and Republic of (United Kingdom Generally Accepted Accounting Practice).

In our opinion, the financial statements:

Basis for opinion

We conducted our audit in accordance with International Standards on Auditing (UK) (ISAs (UK)) and applicable law. Our responsibilities under those standards are further described in for the audit of the financial statements section of our report. We are independent of the group in accordance with the ethical requirements that are relevant to our audit of the financial statements in t have fulfilled our other ethical responsibilities in accordance with these requirements. We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our opinion.

Conclusions relating to going concern

In auditing the financial statements, we have concluded that the trustees' use of the going concern basis of accounting in the preparation of the financial statements is appropriate.

Based on the work we have performed, we have not identified any material uncertainties relating to events or conditions that, individually or collectively, may cast significant doubt on of at least twelve months from when the financial statements are authorised for issue.

Juvenile Diabetes Research Foundation Limited 20

report 30 June 2022

Conclusions relating to going concern (continued)

Our responsibilities and the responsibilities of the directors with respect to going concern are described in the relevant sections of this report.

Other information

The trustees are responsible for the other information. The other information comprises the information included in the d report other than the financial statements and our thereon. Our opinion on the financial statements does not cover the other information and, except to the extent otherwise explicitly stated in our report, we do not express any form of assurance conclusion thereon.

In connection with our audit of the financial statements, our responsibility is to read the other information and, in doing so, consider whether the other information is materially inconsistent with the financial statements or our knowledge obtained in the audit or otherwise appears to be materially misstated. If we identify such material inconsistencies or apparent material misstatements, we are required to determine whether there is a material misstatement in the financial statements or a material misstatement of the other information. If, based on the work we have performed, we conclude that there is a material misstatement of this other information, we are required to report that fact.

We have nothing to report in this regard.

Opinions on other matters prescribed by the Companies Act 2006

In our opinion, based on the work undertaken in the course of the audit:

Matters on which we are required to report by exception

In the light of the knowledge and understanding of the group and the charitable parent company and its environment obtained in the course of the audit, we have not identified material misstatements in the directors report.

We have nothing to report in respect of the following matters in relation to which the Companies Act 2006 and the Charities Accounts (Scotland) Regulations 2006 (as amended) requires us to report to you if, in our opinion:

Juvenile Diabetes Research Foundation Limited 21

report 30 June 2022

Matters on which we are required to report by exception (continued)

Responsibilities of trustees

As explained more fully in the directors responsibilities statement, the trustees are responsible for the preparation of the financial statements and for being satisfied that they give a true and fair view, and for such internal control as the trustees determine is necessary to enable the preparation of financial statements that are free from material misstatement, whether due to fraud or error.

In preparing the financial statements, the trustees are responsible for asses applicable, matters related to going concern and using the going concern basis of accounting unless the trustees either intend to liquidate the group or the charitable parent company or to cease operations, or have no realistic alternative but to do so.

Our objectives are to obtain reasonable assurance about whether the financial statements as a whole are free from material misstatement, whether due to fraud or error, and to issue an report that includes our opinion. Reasonable assurance is a high level of assurance but is not a guarantee that an audit conducted in accordance with ISAs (UK) will always detect a material misstatement when it exists. Misstatements can arise from fraud or error and are considered material if, individually or in the aggregate, they could reasonably be expected to influence the economic decisions of users taken on the basis of these financial statements.

Irregularities, including fraud, are instances of non-compliance with laws and regulations. We design procedures in line with our responsibilities, outlined above, to detect material misstatements in respect of irregularities, including fraud. The extent to which our procedures are capable of detecting irregularities, including fraud is detailed below.

Our approach to identifying and assessing the risks of material misstatement in respect of irregularities, including fraud and non-compliance with laws and regulations, was as follows:

Juvenile Diabetes Research Foundation Limited 22

report 30 June 2022

(continued)

We assessed the susceptibility of the group , including obtaining an understanding of how fraud might occur, by:

To address the risk of fraud through management bias and override of controls, we:

In response to the risk of irregularities and non-compliance with laws and regulations, we designed procedures which included, but were not limited to:

There are inherent limitations in our audit procedures described above. The more removed that laws and regulations are from financial transactions, the less likely it is that we would become aware of non-compliance. Auditing standards also limit the audit procedures required to identify non-compliance with laws and regulations to enquiry of the trustees and other management and the inspection of regulatory and legal correspondence, if any.

Material misstatements that arise due to fraud can be harder to detect than those that arise from error as they may involve deliberate concealment or collusion.

A further description of our responsibilities for the audit of the financial statements is located

Juvenile Diabetes Research Foundation Limited 23

report 30 June 2022

Use of our report

accordance in accordance with Section 44(1)(c) of the Charities and Trustee Investment (Scotland) Act 2005 and Regulation 10 of the Charities Accounts (Scotland) Regulations 2006. Our audit work has been undertaken so that we might state to the charitable company's members those matters we are required to state to them in an auditor's report and for no other purpose. To the fullest extent permitted by law, we do not accept or assume responsibility to anyone other than the charitable company and the charitable company's members as a body, for our audit work, for this report, or for the opinions we have formed.

Buzzacott LLP

21 February 2023

Edward Finch (Senior Statutory Auditor) For and on behalf of Buzzacott LLP, Statutory Auditor 130 Wood Street London EC2V 6DL

Buzzacott LLP is eligible to act as an auditor in terms of section 1212 of the Companies Act 2006.

Juvenile Diabetes Research Foundation Limited 24

Consolidated statement of financial activities Year to 30 June 2022

Notes Unrestricted
funds
£		 Restricted
funds
£		 Total
funds
2022
£		 Unrestricted
funds
£		 Restricted
funds
£		 Total
funds
2021
£
Income and expenditure
Income
Donations and legacies
1
Other trading activities
2
Charitable activities
3
. Research grants
. Support and awareness
Interest receivable
Total income
Expenditure
Cost of raising funds
Charitable activities
. Research funding
. Research advocacy
Subtotal research expenditure
. Support and awareness
Subtotal charitable activities
Total expenditure
4
Net income (expenditure) and net
movement in funds
6
Reconciliation of funds
Total funds brought forward
at 1 July 2021
Total funds carried forward
at 30 June 2022
16		 2,442,738
1,571,709
5,397		 826,788
91,387
970,500		 3,269,526
1,571,709
91,387
970,500
5,397		 2,003,287
879,746
3,062		 643,871
1,084,680
1,761,000		 2,647,158
879,746
1,084,680
1,761,000
3,062
4,019,844 1,888,675 5,908,519 2,886,095 3,489,551 6,375,646
1,933,259
861,211
311,500		 83,302
1,081,527
168,170		 2,016561
1,942,738
479,670		 975,106
428,484
205,285		 695,743
1,940,655
237,234		 1,670,849
2,369,139
442,519
1,172,711 1,249,697 2,422,408 633,769 2,177,889 2,811,658
884,295 191,073 1,075,368 445,319 604,318 1,049,637
2,057,006 1,440,770 3,497,776 1,079,088 2,782,207 3,861,295
3,990,265 1,524,072 5,514,337 2,054,194 3,477,950 5,532,144
29,579
1,817,223		 364,603
406,757		 394,182
2,223,980		 831,901
985,322		 11,601
395,156		 843,502
1,380,478
1,846,802 771,360 2,618,162 1,817,223 406,757 2,223,980

All of the above results are derived from continuing activities.

All recognised gains and losses are included in the above statement of financial activities.

Juvenile Diabetes Research Foundation Limited 25

Balance sheets 30 June 2022

Notes Group Group Charity Charity
2022
£		 2021
£		 2022
£		 2021
£
Fixed assets
Tangible assets
9
Investments
10
Current assets
Debtors
13
Cash at bank and in hand
Liabilities
Creditors: amounts falling due
within one year
14
Net current assets
Total net assets
15
The funds of the charity:
Funds and reserves
16
Restricted funds
Unrestricted funds
. General funds		 81,066
81,066
614,644
2,476,439		 97,078
97,078
423,647
2,140,797		 81,066
10,001
91,067
746,348
2,153,058		 97,078
10,001
107,079
520,293
1,876,628
3,091,083 2,564,444 2,899,406 2,396,921
553,986
2,537,097
2,618,163
771,360
1,846,802		 437,542
2,126,902
2,223,980
406,757
1,817,223		 372,311
2,527,095
2,618,162
771,360
1,846,802		 280,020
2,116,901
2,223,980
406,757
1,817,223
2,618,162 2,223,980 2,618,162 2,223,980

Approved by the directors on 12 December 2022 and signed on their behalf by:

David McTurk Jared Chebib David McTurk Jared Chebib Chair Treasurer

Company Registration Number: 02071638 (England and Wales)

Juvenile Diabetes Research Foundation Limited 26

Consolidated statement of cash flows 30 June 2022

----- Start of picture text -----
2022 2021
Notes £ £
Cash flows from operating activities:
Net cash provided (used in) by operating activities A 347,942 986,499
Cash flows from investing activities:
Interest received 5,397 3,062
Purchase of tangible fixed assets (17,699) (12,787)
Net cash used in investing activities (12,302) (9,725)
Change in cash and cash equivalents in the year 335,640 976,774
Cash and cash equivalents at 1 July 2021 B 2,140,799 1,164,023
Cash and cash equivalents at 30 June 2022 B 2,476,439 2,140,797
Notes to the statement of cash flows for the year to 30 June 2022.
A Reconciliation of net movement in funds to net cash provided by operating activities
2022 2021
£ £
Net movement in funds (as per the statement of financial activities) 394,182 843,502
Adjustments for:
Depreciation charge 33,711 31,599
Interest receivable (5,398) (3,062)
(Increase) in debtors (190,997) (13,096)
Increase (decrease) in creditors 116,444 127,556
Net cash provided by (used in) operating activities 347,942 986,499
B Analysis of changes in net debt
At 1 Movement At 30 June
July 2021 in year 2022
£ £ £
Cash at bank and in hand 2,140,797 335,640 2,476,439
Total cash and cash equivalents 2,140,797 335,640 2,476,439
----- End of picture text -----

Juvenile Diabetes Research Foundation Limited 27

Principal accounting policies 30 June 2022

The principal accounting policies adopted, judgements and key sources of estimation uncertainty in the preparation of the accounts are laid out below.

Basis of preparation

These financial statements have been prepared for the year to 30 June 2022.

The financial statements have been prepared under the historical cost convention with items recognised at cost or transaction value unless otherwise stated in the relevant accounting policies below or the notes to these financial statements.

The financial statements have been prepared in accordance with Accounting and Reporting by Charities: Statement of Recommended Practice applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the United Kingdom and Republic of Ireland (Charities SORP FRS 102), the Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS 102) and the Companies Act 2006.

The charity constitutes a public benefit entity as defined by FRS 102.

The financial statements are presented in sterling and are rounded to the nearest pound.

Basis of Consolidation

The statement of financial activities and balance sheet consolidate the assets, liabilities, income and expenditure of the charity and its wholly owned subsidiary undertaking, JDRF Trading Limited. The results of the subsidiary undertaking are consolidated on a line-by-line basis.

No separate statement of financial activities or statement of cashflows has been prepared for the charity above as permitted by Section 408 of the Companies Act 2006.

Critical accounting estimates and areas of judgement

Preparation of the financial statements requires the trustees and management to make significant judgements and estimates.

The items in the financial statements where these judgements and estimates have been made include:

assessing the probability of receipt of legacy income;

Juvenile Diabetes Research Foundation Limited 28

Principal accounting policies 30 June 2022

Assessment of going concern

The trustees have assessed whether the use of the going concern assumption is appropriate in preparing these financial statements. The trustees have made this assessment with respect to a period of one year from the date of approval of these financial statements.

The trustees of the charity have concluded that there are no material uncertainties related to events or conditions that may cast significant doubt on the ability of the charity to continue as a going concern. In making this assessment, the trustees have considered the impact of the Coronavirus outbreak on the group and charity, specifically they have considered the availability of future funding from grants and donations and the ability to continue to fund charitable activities through available reserves. The trustees are of the opinion that the charity will have sufficient resources to meet its liabilities as they fall due.

Income recognition

Income is recognised in the period in which the charity has entitlement to the income, the amount of income can be measured reliably and it is probable that the income will be received.

Income received by way of subscriptions, donations and gifts to the charity is included in full in the statement of financial activities when receivable. Donations are recognised when the charity has confirmation of both the amount and settlement date. In the event of donations pledged but not received, the amount is accrued for where the receipt is considered probable. In the event that a donation is subject to conditions that require a level of performance before the charity is entitled to the funds, the income is deferred and not recognised until either those conditions are fully met, or the fulfilment of those conditions is wholly within the control of the charity and it is probable that those conditions will be fulfilled in the reporting period.

Donated services and facilities provided to the charity are recognised in the period when it is probable that the economic benefits will flow to the charity, provided they can be measured reliably. This is normally when the service is provided. An equivalent amount is included as expenditure.

Donated services and facilities are recognised on the basis of the value of the gift to the charity which is the amount the charity would have been willing to pay to obtain facilities or services of equivalent economic benefits on the open market.

Legacies are included in the statement of financial activities when the charity is entitled to the legacy, the executors have established that there are sufficient surplus assets in the estate to pay the legacy, and any conditions attached to the legacy are within the control of the charity.

Juvenile Diabetes Research Foundation Limited 29

Principal accounting policies 30 June 2022

Income recognition (continued)

Entitlement is taken as the earlier of the date on which either: the charity is aware that probate has been granted, the estate has been finalised and notification has been made by the executor to the charity that a distribution will be made, or when a distribution is received from the estate. Receipt of a legacy, in whole or in part, is only considered probable when intention to make a distribution. Where legacies have been notified to the charity, or the charity is aware of the granting of probate, but the criteria for income recognition have not been met, then the legacy is treated as a contingent asset and disclosed if material. In the event that the gift is in the form of an asset other than cash or a financial asset traded on a recognised stock exchange, recognition is subject to the value of the gift being reliably measurable with a degree of reasonable accuracy and the title of the asset having being transferred to the charity.

Revenue grants are credited to the statement of financial activities when received or receivable whichever is earlier.

Where unconditional entitlement to grants receivable is dependent upon fulfilment of conditions within the charity's control, the incoming resources are recognised when there is sufficient evidence that conditions will be met. Where there is uncertainty as to whether the charity can meet such conditions the incoming resource is deferred.

Interest on funds held on deposit is included when receivable and the amount can be measured reliably by the charity; this is normally upon notification of the interest paid or payable by the bank.

Resources expended

Liabilities are recognised as expenditure as soon as there is a legal or constructive obligation committing the charity to make a payment to a third party, it is probable that a transfer of economic benefits will be required in settlement and the amount of the obligation can be measured reliably.

All expenditure is accounted for on an accruals basis.

Expenditure is allocated to a particular activity where the cost relates directly to that activity. Expenditure includes attributable VAT which cannot be recovered. The cost of overall direction and administration of each activity, comprising the salary and overhead costs of the central functions, is apportioned on the basis of an estimate, based on staff time, of the amount attributable to each activity.

Premises and office costs are allocated based on the amount of floor space attributable to each activity, except for regional offices which are split 75% cost of generating funds, 5% research advocacy and 20% support and awareness.

Governance costs are the costs associated with the governance arrangements of the charity. These costs are associated with constitutional and statutory requirements and include any costs

Juvenile Diabetes Research Foundation Limited 30

Principal accounting policies 30 June 2022

Resources expended (continued)

The costs of raising funds relate to the costs incurred by the group in raising funds for the charitable work.

Where information about the aims, objectives and projects of the charity is provided to potential beneficiaries, the costs associated with this publicity are allocated to charitable activities. Where such information about the aims, objectives and projects of the charity is also provided to potential donors, activity costs are apportioned between fundraising and charitable activities.

Grants payable are charged to the statement of financial activities in the year in which agreement to pay has been reached with . Provision is made for grants agreed and approved but unpaid at the period end.

Tangible fixed assets

Items of equipment are capitalised where the purchase price exceeds £1,000 including irrecoverable VAT.

Depreciation is provided at rates calculated to write down the cost of each asset to its estimated residual value over its expected useful life. The depreciation rates in use are as follows:

Leasehold improvements Over the lifetime of the lease

Computer equipment 5 years Fixtures and fittings 5 years

Depreciation costs are allocated to activities on the basis of the use of the related assets in those activities. Assets are reviewed for impairment if circumstances indicate their carrying value may exceed their net realisable value or value in use.

Investments

Investments held as fixed assets subsidiary trading company and are stated at cost.

Debtors

Debtors are recognised at their settlement amount, less any provision for non-recoverability. Prepayments are valued at the amount prepaid.

Cash at bank and in hand

Cash at bank and in hand represents such accounts and instruments that are available on demand or have a maturity of less than three months from the date of acquisition.

Creditors and provisions

Creditors and provisions are recognised when there is an obligation at the balance sheet date as a result of a past event, it is probable that a transfer of economic benefit will be required in settlement, and the amount of the settlement can be estimated reliably. Creditors and provisions are recognised at the amount the charity anticipates it will pay to settle the debt.

Juvenile Diabetes Research Foundation Limited 31

Principal accounting policies 30 June 2022

Leases

Rentals payable under operating leases, where substantially all the risks and rewards of ownership remain with the lessor, are charged to the statement of financial activities over the life of the lease using the straight line basis.

Pension scheme

JDRF contributes to staff group personal pension plans. The pension charge represents payments to the scheme which are charged to the statement of financial activities in the period to which they relate. Employer contributions are 4% after 3 months, 5% after 2 years additionally sacrifice up to 10% of gross salary to their pension. The charitable company has no liability under the scheme other than for the payment of these contributions.

Fund accounting

Restricted funds are to be used for specified purposes as laid down by the donor. Expenditure which meets these criteria is identified to the fund.

Unrestricted funds are donations and other incoming resources received or generated for the charitable purposes.

Designated funds are unrestricted funds earmarked by the directors for particular purposes.

Foreign exchange

Balance sheet assets/liabilities in foreign currencies are translated at the prevailing exchange rate at the balance sheet date. Transactions are translated at the transaction date exchange rate. Any exchange rate differences arising are credited or charged to the statement of financial activities.

Financial instruments

The charity only holds basic financial instruments as defined in FRS 102. The financial assets and financial liabilities of the charity and their measurement basis are as follows:

Financial assets Other debtors are basic financial instruments and are debt instruments measured at amortised cost. Prepayments are not financial instruments.

Cash at bank Classified as a basic financial instrument and is measured at face value.

Financial liabilities accruals and other creditors are financial instruments, and are measured at amortised cost.

Juvenile Diabetes Research Foundation Limited 32

Notes to the financial statements 30 June 2022

1 Income from donations and legacies

Unrestricted
funds
£		 Restricted
funds
£		 Total
funds
2022
£		 Unrestricted
funds
£		 Restricted
funds
£		 Total
funds
2021
£
Donations
Legacies
Third party fundraising
Total		 1,707,365
130,392
604,981
2,442,738		 826,788
826,788		 2,534,153
130,392
604,981
3,269,526		 1,605,904
41,900
355,483
2,003,287		 563,871
80,000
643,871		 2,169,775
121,900
355,483
2,647,158

2 Income from trading activities

Unrestricted
funds
£		 Restricted
funds
£		 Restricted
funds
£		 Total
funds
2022
£		 Unrestricted
funds
£		 Restricted
funds
£		 Total
funds
2021
£
One Walk
Running and challenge events
Corporate sponsorship,
advertising and merchandise
Events and other fundraising
activities
Rental/other income
Coronavirus Job Retention
Scheme
Total		 152,691
732,297
362,879
245,711
78,131
1,571,709		 152,691
732,297
362,879
245,711
78,131
1,571,709		 26,087
378,063
287,571
91,899
31,014
65,112
879,746		 26,087
378,063
287,571
91,899
31,014
65,112
879,746

3 Income from charitable activities

----- Start of picture text -----
2022 2021
Total Total
Restricted Restricted
£ £
Research grants
The Steve Morgan Foundation 1,000,000
The Cadogan Charity 50,000
Miss Margaret Butters Reekie Charitable Trust 5,000
The R S Macdonald Charitable Trust 10,000 10,000
Nimar Charitable Trust 10,000 5,000
PF Charitable Trust 10,000
Shepherd and Wedde Barr Charitable Trust 15,000
The R S Macdonald Charitable Trust 20,000
Robert Luff Foundation Limited 15,000
Contributions £5,000 or less 11,387 14,680
91,387 1,084,680
Support and awareness
The Steve Morgan Foundation (DCMS Community Match Challenge 50%)
Department of Culture, Media and Sport (Community Match Challenge 50%) 937,500 1,500,000
The Steve Morgan Foundation 187,500
Coldstones Charitable Trust 15,000
The Mercers' Company 5,000
The Hugh Fraser Foundation 7,500
Hummingbird Charitable Trust 45,000
Peter Harrison Foundation 20,000
The Big Lottery Fund 10,000
Contributions £5,000 or less 3,000 1,000
970,500 1,761,000
Total 1,061,887 2,845,680
----- End of picture text -----

Juvenile Diabetes Research Foundation Limited 33

Notes to the financial statements 30 June 2022

4 Total expenditure

Total expenditure
Unrestricted
funds
£		 Restricted
funds
£		 Total
funds
2022
£		 Unrestricted
funds
£		 Restricted
funds
£		 Total
funds
2021
£
Costs of raising funds
Charitable activities
. Research funding
. Research advocacy
. Support and awareness
Total		 1,933,259
852,395
311,500
884,295
3,981,449		 83,302
1,090,343
168,170
191,073
1,532,888		 2,016,561
1,942,738
479,670
1,075,368
5,514,337		 975,106
428,484
205,285
445,319
2,054,194		 695,743
1,940,655
237,234
604,318
3,477,950		 1,670,849
2,369,139
442,519
1,049,637
5,532,144
Note Cost of
raising
funds
£		 Research
funding
£		 Research
advocacy
£		 Support
and
awareness
£		 Governance
costs
£		 Support
costs
£		 2022
Total
£
Staff costs
7
Other staffing costs
Office costs
Rent and premises
Depreciation
Information technology costs
Direct fundraising costs
. Donations and appeals
. Third party fundraising
. One Walk
. Running and challenge
events
. Trading activities
. Events and other
fundraising activities
Subtotal direct fundraising
costs
Audit fees
Governance
Advocacy
Support and awareness
Research grants
unrestricted
5
Research grants
restricted
5
Support costs
Governance costs
Total expenditure 2022		 939,628
(3,278)
101,946
123,581
86,640
225,287
2,591
131,945
5,758
45,895		 234,374
(818)
13,832
19,192
16,301		 275,755
29,525
15,508
16,589
12,868		 478,361
(1,669)
32,698
41,103
30,024		 101,886
(355)
2,247
3,030
2,573		 339,014
64,899
50,834
43,434
33,711
36,887		 2,369,018
88,304
217,065
246,929
33,711
185,293
225,287
2,591
131,945
5,758
45,895
411,476 411,476
5,354
510,859
1,060,748		 42,845 322,490 13,067
7,178		 13,067
7,178
48,199
322,490
510,859
1,060,748
1,659,993
290,388
66,180		 1,859,842
67,510
15,386		 393,090
70,511
16,069		 903,007
140,370
31,991		 129,626
(129,626)		 568,779
(568,779)		 5,514,337
2,016,561 1,942,738 479,670 1,075,368 5,514,337

Juvenile Diabetes Research Foundation Limited 34

Notes to the financial statements 30 June 2022

4 Total expenditure (continued)

Note Cost of
raising
funds
£		 Research
funding
£		 Research
advocacy
£		 Support
and
awareness
£		 Governance
costs
£		 Support
costs
£		 2021
Total
£
Staff costs
7
Other staffing costs
Office costs
Rent and premises
Depreciation
Information technology costs
Direct fundraising costs
. Donations and appeals
. Third party fundraising
. One Walk
. Running and challenge
events
. Trading activities
. Events and other
fundraising activities
Subtotal direct fundraising
costs
Audit fees
Governance
Advocacy
Support and awareness
Research grants
unrestricted
5
Research grants
restricted
5
Support costs
Governance costs
Total expenditure 2021		 974,503
4,322
47,689
140,523
51,717
112,387
6,243
52,407
805
9,318		 226,556
393
7,153
18,094
9,729		 236,624
21,918
8,923
17,241
7,681		 471,064
27,927
15,467
45,155
17,923		 104,099
181
993
2,856
1,536		 275,115
13,183
18,175
40,949
31,599
22,018		 2,287,961
67,924
98,400
264,818
31,599
110,604
112,387
6,243
52,407
805
9,318
181,160 181,160
3,875
246,797
1,793,554		 84,345 341,135 12,545
7,427		 12,545
7,427
88,220
341,135
246,797
1,793,554
1,399,914
204,749
66,186		 2,306,151
47,601
15,387		 376,732
49,716
16,071		 918,671
98,973
31,993		 129,637
(129,637)		 401,039
(401,039)		 5,532,144
1,670,849 2,369,139 442,519 1,049,637 5,532,144

Juvenile Diabetes Research Foundation Limited 35

Notes to the financial statements 30 June 2022

5 Research grants

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2022 2021
Principal Restricted Unrestricted Total Restricted Unrestricted Total
investigator £ £ £ £ £ £
University of Exeter Angus Jones
Defining the decline in endogenous insulin secretion in Type 1
diabetes diagnosed after 30 years of age
Cardiff University Colin Dayan 182,561 201,733 384,294
Microneedle arrays to deliver antigen specific immunotherapy
Cardiff University Colin Dayan 77,911 77,911
Clinical Trials in the Type 1 Diabetes UK Immunotherapy
Consortium: Bigger, Smarter, Faster
Cardiff University Colin Dayan 380,547 380,547
The beta-2 score and beyond: new composite outcomes
measures of islet cell function for use in clinical trials
Medical Research Council (MRC) Dania Grant 54,625 54,625
PEG-Based Hydrogels for iPSCs-Derived Regenerative
Therapies for Diabetes (PI: Rocio Sancho)
Queen's University Belfast Eleni Beli
Novel Insights on the Link between Diabetic Retinopathy and
the Splenic Clock
The University of Edinburgh Helen Colhoun 196,301 196,301
Using Deep Learning on Retinal Images to Predict
Complications and Therapeutic responses in Type 1 Diabetes
University of Bristol Yuk-Fun Liu
UK TrialNet Clinical Center
University of Bristol Kathleen Gillespie 60,042 36,449 96,491
How do Slow Progressors to type 1 diabetes regulate their
autoimmune response ?
University of Exeter Richard Oram 169,931 169,931 136,723 (245) 136,478
Improved, cost effective prediction of type 1 diabetes in early
life using combined prediction models
King's College London Gavin Bewick 172,315 91,308 263,623 41,826 41,826
Exploring the translational potential of the NPY Y4 receptor for
treating Type 1 Diabetes
King's College London Stephanie Amiel 5,917 5,917 16,125 16,125
A Hypoglycemia Awareness Restoration Program for people
with type 1 diabetes and problematic hypoglycemia persisting
King's College London Timothy Tree 95,656 95,656 136,163 136,163
Harmonizing biomarkers in clinical trials of ustekinumab
University of Exeter Paul W Potter 43,323 43,323 5,359 9,641 15,000
Modulation of brain fatty acid oxidation to improve
hypoglycemia counterregulation
University of Oxford Paul Johnson 17,664 801 18,465
Human Islets For Basic Research- Oxford JDRF Human Islet
Resource Centre
University of Bristol Polly Bingley 30,735 30,735
JDRF International Clinical Sites - UK (Trialnet)
University of Dundee Rory McCrimmon 4,819 112 4,931
Restoring hypoglycemia awareness through dishabituation
University of Oxford Kerry McLaughlin 20,863 20,863
Role of the autoantigen tetraspanin-7 in type 1 diabetes
University of Lincoln Michael Christie 54,142 54,142
Phenotype and specificity of the islet inflammation in Type 1
diabetes
University of Bristol Anna Long 18,267 18,267 47,890 47,890
Adult onset Type 1 Diabetes: Slow Progressors or Late
Starters?
Mark Peakman 32,447 32,447
Comparison of neo- and natural epitope reactivity as it relates
to Disease Stage, T cell recruitment and polarization
Institute for Med Res, Univ of Cambridge Eoin McKinney 294,317 294,317
TrialNet Transcriptomic Pipeline
Cardiff University James Pearson 15,000 15,000
Do time-of-day-dependent changes in regulatory T-cells alter
their ability to suppress the development of Type 1 diabetes in
NOD mice
University of Exeter Martin Eichamnn 14,858 14,858
Killing the beta cell killers to slow progression and prevent
type 1 diabetes
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Juvenile Diabetes Research Foundation Limited 36

5 Research grants (continued)

Notes to the financial statements 30 June 2022

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2022 2021
Principal Restricted Unrestricted Total Restricted Unrestricted Total
investigator £ £ £ £ £ £
University of Exeter Yu Hsuan Carol Yang 15,000 15,000
Does it take a lot of nerve to regenerate pancreatic beta cells
University of Bristol Kathleen Gillespie 55,362 15,000 70,362 10,126 21,615 31,741
COVID-19 antibody screening in families with type 1 diabetes:
infection rate and effects on diabetes
PEG-Based Hydrogels for iPSCs-Derived Regenerative Julie Cawley / Rocio
Therapies for Diabetes Sancho 54,825 54,825
JDRF T1D Fund 290,464 8,816 299,280 268,883 268,883
University of Edinburgh (Connect Immune Research
award) Yannick Crow 16,133 16,133 17,822 17,822
Precision type I interferon biomarkers for the stratification of
autoimmune disease
Paul Weightman
University of Exeter Potter 45,186 45,186
Modulation of brain fatty acid oxidation to improve
hypoglycaemia counter regulation
University of Birmingham Parth Narendran 29,167 90,952 120,119
Testing the feasibility and acceptability of EarLy Surveillance
for Autoimmune diabetes: The ELSA Study
P Choudhary 6,481 6,481
Mixed methods study exploring the impact of hybrid closed-
loop systems on patient reported outcomes in people with type
I diabetes and their partners
1,060,748 510,859 1,571,607 1,793,554 246,797 2,040,351
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Juvenile Diabetes Research Foundation Limited 37

Notes to the financial statements 30 June 2022

6 Net income (expenditure) before transfers

This is stated after charging:

2022
£		 2021
£
Depreciation
. Audit for current year
Operating lease rentals
. Property		 33,711
541
13,067
152,511		 31,599
541
10,585
158,048
2022
£		 2021
£
Salaries and wages
Social security costs
Pension contributions
Redundancy		 2,013,902
205,385
94,798		 1,978,658
193,352
112,272
2,314,085 2,284,282
54,933 3,679
2,369,018 2,287,961

The average weekly number of employees (on an average head count and a full time equivalent basis) was as follows:

Head count
2022		 Head count
2021		 FTE
2022		 FTE
2021
Raising funds
Charitable activities
Central support		 22.0
23.1
10.3
55.4		 24.0
23
9
56		 20.6
21.7
9.7
52.0		 22.2
21.2
8.6
52.0

The key management personnel of the charity in charge of directing and controlling, running and operating the charity on a day to day basis comprise the trustees, and the executive management team. The total remuneration (including taxable benefits and pension contributions) of the key management personnel for the year was £456,773 (2021 - £431,701).

During the year JDRF made non contractual severance payments of £54,933 (2021: £3,679). These payments were approved by the trustees for payment.

2022
£
1
1
2		 2021
£
1
1
Employee between £90k & £100k
Employee between £70k & £80k
Employee between £60k & £70k

The pension contributions paid during the year for these employees totalled £42,174 (2021 - £43,831).

Juvenile Diabetes Research Foundation Limited 38

Notes to the financial statements 30 June 2022

7 Taxation

The charity is exempt from corporation tax as all its income is charitable and is applied for available profits to the charity.

8 Tangible fixed assets

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Leasehold Computer Fixtures
improvements equipment and fittings Total
£ £ £ £
Cost
At 1 July 2021 108,381 155,303 7,176 270,860
Additions in the year 17,699 17,699
At 30 June 2022 108,381 173,002 7,176 288,559
Depreciation
At 1 July 2021 75,137 91,469 7,176 173,782
Charge for the year 11,081 22,630 33,711
At 30 June 2022 86,218 114,099 7,176 207,493
Net book value
At 30 June 2022 22,163 58,903 81,066
At 30 June 2021 33,244 63,834 97,078
Investments
2022 2021
£ £
Investment in unquoted subsidiary undertaking at cost 10,001 10,001
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9 Investments

Juvenile Diabetes Research Foundation Limited 39

Notes to the financial statements 30 June 2022

10 Subsidiary undertaking

The charitable company owns the whole of the issued ordinary share capital of JDRF Trading Limited, a company registered in England on 17 December 2007. The subsidiary is used for non-primary purpose trading activities. All activities have been consolidated on a line by line basis in the statement of financial activities. Available profits are gift aided to the charitable company. A summary of the results of the subsidiary is shown below:

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2022 2021
£ £
Turnover 338,579 282,097
Cost of sales
Gross profit 338,579 282,097
Administrative expenses (64,617) (53,979)
Operating profit 273,962 228,118
Taxation
Profit on ordinary activities after taxation 273,962 228,118
Gift aid distribution to parent undertaking (273,962) (228,118)
Movement in retained earnings
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The aggregate of the assets, liabilities and funds was:

2022
£		 2021
£
Assets
Liabilities
Funds		 395,981
(385,980)		 327,313
(317,312)
10,001 10,001

11 Parent undertaking

2022
£		 2021
£
Gross income
Results for theyear		 5,569,940
120,220		 6,093,549
615,385

12 Debtors

Debtors
Group Charity
2022
£		 2021
£		 2022
£		 2021
£
Trade debtors
Other debtors
Amounts due from subsidiary
Prepayments
Accrued income		 94,450
235
204,506
315,453		 72,394
222,209
129,044		 21,849
204,540
204,506
315,453		 9,250
159,790
222,209
129,044
614,644 423,647 746,348 520,293

Juvenile Diabetes Research Foundation Limited 40

Notes to the financial statements 30 June 2022

13 Creditors: amounts due within one year

Group Group Charity Charity
2022
£		 2021
£		 2022
£		 2021
£
Trade creditors
Taxation and social security
Other creditors
Rent free benefit over lease period
Deferred income
Accrued costs		 51,749
78,594
45,845
14,487
174,088
189,223		 55,010
65,437
28,249
19,836
144,750
124,260		 51,749
66,081
45,845
14,487
7,425
189,223		 55,010
48,665
28,249
19,836
4,000
124,260
553,986 437,542 372,311 280,020

Included in deferred income are amounts received in advance for events and sponsorship as set out below:

Group Group Charity Charity
2022
£		 2021
£		 2022
£		 2021
£
Brought forward as at 1 July
Additional income deferred in year
Brought forward funds released in year
Carried forward as at 31 June		 144,750
174,088
(144,750)		 122,642
144,750
(122,642)		 4,000
7,425
(4,000)		 4,000
174,088 144,750 7,425 4,000

14 Analysis of net assets between funds

Group Restricted
funds
£		 Unrestricted
funds
£		 Total
funds
2022
£		 Restricted
funds
£		 Unrestricted
funds
£		 Total
funds
2021
£
Tangible fixed assets
Net current assets
Net assets at 30 June		 771,360
771,360		 81,066
1,765,736
1,846,802		 81,066
2,537,096
2,618,162		 406,757
406,757		 97,078
1,720,145
1,817,223		 97,078
2,126,902
2,223,980
Charity Restricted
funds
£		 Restricted
funds
£		 Unrestricted
funds
£		 Total
funds
2022
£		 Restricted
funds
£		 Unrestricted
funds
£		 Total
funds
2021
£
Tangible fixed assets
Investments
Net current assets
Net assets at 30 June		 771,360
771,360		 81,066
10,001
1,755,735
1,846,802		 81,066
10,001
2,527,095
2,618,162		 406,757
406,757		 97,078
10,001
1,710,144
1,817,223		 97,078
10,001
2,116,901
2,223,980

Juvenile Diabetes Research Foundation Limited 41

Notes to the financial statements 30 June 2022

15 Movement in funds

Movement in funds
At 1
July
2021
£		 Income
£		 Expenditure
£		 At 30
June
2022
£
Restricted funds
Research funding
Steve Morgan Foundation
Support and awareness
CMC Funding
Total restricted funds
Unrestricted funds
General funds
Total funds		 307,852
2,690
10,000
86,215		 918,175
33,000
937,500		 (1,060,749)
(463,323)		 165,278
2,690
43,000
560,392
406,757 1,888,675 1,524,072) 771,360
1,817,223 4,019,844 (3,990,265) 1,846,802
2,223,980 5,908,519 (5,514,337) 2,618,162
At 1
July
2020
£		 Income
£		 Expenditure
£		 At 30
June
2021
£
Restricted funds
Research funding
Steve Morgan Foundation
Support and awareness
CMC Funding
Total restricted funds
Unrestricted funds
General funds
Total funds		 338,626
28,930
27,600		 728,551
1,000,000
73,500
1,687,500		 (759,325)
(1,026,240)
(91,100)
(1,601,285)		 307,852
2,690
10,000
86,215
395,156 3,489,551 (3,477,950) 406,757
985,322 2,886,095 (2,054,194) 1,817,223
1,380,478 6,375,646 (5,532,144) 2,223,980

Purpose of restricted funds

Restricted funds are received for the purpose of carrying out particular activities; usually research grant funding, support and awareness and advocacy activities. They either directly contribute to these activities, or are applied to core costs related to information/education about type 1 diabetes and the related dissemination of research information.

Juvenile Diabetes Research Foundation Limited 42

Notes to the financial statements 30 June 2022

16 Operating lease commitments

The group and charity had future minimum commitments at the year end under operating leases as follows:

Payments which fall due: 2022
Land and
buildings
£		 2021
Land and
buildings
£
Less than one year
Between two and five years		 171,699
470,720		 179,409
472,245
642,419 651,654

17 Related party transactions

Trustee expenses for the year totalled £nil (2021 - £nil) and charitable donations received from trustees totalled £50,923 (2021 - £38,575).

There were no other transactions with related parties which required disclosure during the year (2021 - none).

Juvenile Diabetes Research Foundation Limited 43