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2021-12-31-accounts

REGISTERED COMPANY NUMBER: 01676618 (England and Wales) REGISTERED CHARITY NUMBER: 286197

Report of the Trustees and

Unaudited Financial Statements for the Year Ended 31 December 2021

for

The British Toxicology Society

Sutton McGrath Hartley 5 Westbrook Court Sharrowvale Road Sheffield South Yorkshire S11 8YZ

The British Toxicology Society

Contents of the Financial Statements for the Year Ended 31 December 2021

Page
President's Report 1 to 8
Operating and Financial Review 9 to 10
Report of the Trustees 11 to 12
Independent Examiner's Report 13
Statement of Financial Activities 14
Balance Sheet 15 to 16
Notes to the Financial Statements 17 to 23
Detailed Statement of Financial Activities 24 to 26

The British Toxicology Society

President's Report for the Year Ended 31 December 2021

As a Society we have continued to promote the positive impact of toxicology, and to support and represent members in all areas we represent. I am delighted that we have been able to maintain a constant membership level of 981 members which has been another increase on last year. I would like to thank our members for your continued support of the Society.

September 2021 marked 50 years since the inception of the BTS. It started from very humble beginnings, when in 1971 (the year decimalisation was introduced) two University of Surrey staff members, namely Professors Jim Bridges and Ron Walker, formed the Toxicology Club. It is amazing how a discussion at 2am in the morning in a KUB (Kitchen, Utility and Breakfast room in Surrey speak!!) at the University led eventually to the founding of the British Toxicology Society in 1979- the Society we know now! Those humble beginnings set out the path for a Society whose remit has always been to promote the advancement of the science of toxicology, for public benefit. The Toxicology Club membership initially was made up of UK based toxicologists, but the Society is proud to have, amongst its numbers, many members from across the world. Members total around 900 currently and work in academic, clinical, governmental, and industrial organisations.

The Executive Committee have discussed the 2020-2024 Strategic Vision of the Society at its meetings over the last year to ensure that the aims are being met and, where required, updated. The Strategy for 2020-2024 can be found on the website (Strategy-of-the-BTS-2020-2024- 2020). This year several updates and commitments to the previous strategy were made taking on board members' feedback. We will shortly publish an updated Strategy which will take the Society through to the end of 2026 and we will share details of this with members over the coming months.

In addition to overarching Strategy 2020-24 we have set out our Equality, Diversity and Inclusion (EDI) Strategy and I am pleased to welcome our EDI co-opted member, Professor Winston Morgan, to the Executive Committee.

Professor Morgan will work with Drs Emma Marczylo and David Mason to drive our EDI agenda. We have also applied to join the Equality, Diversity and Inclusion in Science and Health (EDIS) organisation to support our work in the EDI arena. EDIS is a coalition of organisations working to improve equality, diversity and inclusion within the science and health research sector, originally established by the Francis Crick Institute, Wellcome Trust and GlaxoSmithKline . I will be able to update the membership at the AGM in April 2022 to confirm if our application to EDIS was successful. For more details on EDIS please visit their website: https://edisgroup.org/

Co-opted Members for 2022-2024

At every Annual General Meeting (AGM) I, as your President, need to inform you of those members who have been co-opted to vacancies on the Executive Committee. These positions were advertised to the membership during the year.

Dr Helen Nakeeb has been appointed to the Chair of the Education, Career and Training Development (ECTD) Subcommittee. Dr Nakeeb succeeds Dr Tina Mehta and takes up this position as on the 4th April 2022. Dr Nakeeb applied, and was recommended, for this position to the Executive Committee by the Nominations Subcommittee. The Executive Committee was in full agreement to support this application of Dr Nakeeb for the co-opted position as Chair of the ECTD Subcommittee. As this is a co-opted position it does not need to be ratified at the AGM. The term of office is 3 years, but the Chair can be proposed to serve for a second term. I would like to welcome Dr Nakeeb to the Executive Committee.

Professor Morgan has been appointed to the role of EDI Co-ordinator. Professor Morgan accepted this position on 26th January 2022. This appointment was made through a competitive process. All applicants were interviewed, and the decision of the Interview Panel (Drs Carol Courage, Emma Marczylo and David Mason) was ratified by the Executive Committee. This is a co-opted position which does not need to be ratified at this AGM. The term of office is 3 years, but the holder can be proposed for a second term. I would like to welcome Professor Morgan to the Executive Committee.

Awards to our Members 2021/22

Before presenting some of the highlights from this year I would like to acknowledge some of the awards received by our members in 2021/22.

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The British Toxicology Society

President's Report for the Year Ended 31 December 2021

I am pleased to provide a summary of what has been accomplished since the last AGM and I hope that this is helpful and of interest. Details of some of what is presented below is provided in the relevant reports from the Chairs of the subcommittees.

Risk Register

We took the opportunity to review and update the Society's Risk Register and to consider any effects the pandemic may have had/will have on the sustainability of the Society. I am pleased to report that as a Society the pandemic did not have a significant adverse effect on our finances and the Society remains in a sustainable position.

The main subcommittees of the Society have been very active over the last year, and it has been a pleasure to be able to attend some of their virtual meetings to meet with the members and hear what is going on first-hand.

Membership

The Membership of the BTS has continued to increase, with 981 members as of December 2021. It is good to see this continual increase in numbers, although the Executive Committee are keen to ensure these numbers continue to increase and that we ensure we meet our mission "To provide the principal forum for toxicology in the UK, to support and enrich the carers of toxicologists, and to promote the importance and advancement of toxicology in the wider and lay communities".

My thanks to Lisa Godfrey, our Membership Facilitator who has been undertaking a lot of work to promote membership of the Society and the benefits offered to our members. A list of current benefits can be found here https://www.thebts.org/wp-content/uploads/2020/11/Members-Benefits-June-2020.pdf

I am sure over the coming months you will be hearing from Lisa to gauge your views as members and what more can be done to support our members and attract new members to the Society.

Retirement Policy

The Executive Committee considered the subscription payable by our retired members and whether we are in line in line with that of other Societies. It was proposed to increase the fee payable by our retired members from 40% to 50% of the full membership fee.

Following discussions with a Focus Group, representing members of the Society, and chaired by Professor Heather Wallace, they raised a number of points for the Executive Committee to consider:

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The British Toxicology Society

President's Report for the Year Ended 31 December 2021

It was clear from discussions that the change in the percentage of the fee payable by a retired member from 40% to 50% of the full membership fee was not an issue from the discussions with the Focus Group, providing any increases in fees were undertaken at the same time as any increases being considered for the membership fees payable by full members. The agreement was that if the fee was to be increased it would not be levied until all membership fees were increased.

The proposal regarding the increase in the fee payable from 40% to 50% of the full membership fee was considered by the Executive Committee at its meeting on the 26th January 2022 taking into account the views of the Focus Group and members of the Executive Committee and the following was agreed following a vote:

The proposal by the Focus Group regarding the definition for retirement was considered by the Executive Committee at its meeting on the 26th January 2022 .

The other two proposals from the Focus Group will be considered by the Executive Committee at its meetings in the coming year and the outcomes reported to the membership at the 2023 AGM.

I would like to take this opportunity to thank Professor Wallace and the Focus Group for their considered comments on this issue.

Project Co-ordinator: Skills gap in Toxicology

In 2021 the Executive Committee supported the initiative for the BTS to lead on looking at the Skills Gap in Regulatory Toxicology. The Project Co-Ordinator Role was advertised through the BTS website, and we received a number of applications. The Interview Panel (Drs Phil Botham, Emma Barnes, Cath Mulholland, David Gott and myself) considered the applicants and after shortlisting and interviews we were pleased to appoint Dr Sarah Judd, Newcastle University. Sarah who is working as a consultant to the BTS is consulting with industry, regulatory, NGOs and academia representatives to understand and identify gaps in training. This appointment is for a period of 6 months in the first instance working with the Executive Committee and there will be regular updates on progress through the Newsletter and website. A final report will be published later this year as to the findings and conclusions of this exercise.

Work of the Subcommittees

The main subcommittees of the Society have been very active over the last year, and it has been a pleasure to be able to attend some of their virtual meetings to meet with the members and hear what is going on first-hand.

The sustainability of the Society depends on ensuring that there is a clear succession plan in place and the Nomination Subcommittee (NSC), chaired by Dr Chris Powell, oversees this activity on behalf of the Executive Committee and we are in a very secure position going forward. As always, if you would like to be considered as a member of a subcommittee or Chair, please send your name and a short biography to bts@execbs.com

The NSC have also considered exceptional applications for the Paton Prize. The Paton Prize is in honour of Sir William Paton to encourage scholarships in the historical aspects of toxicology. This year the recipient is Professor Faith Williams.

The Mid-Career Achievement Award, made in recognition of the achievements of an exceptional mid-career member of the BTS, will also be awarded at the Annual Congress but at the time of writing the recipient had not been confirmed.

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The British Toxicology Society

President's Report for the Year Ended 31 December 2021

The Society's finances are overseen by our Treasurer, Professor Rob Chilcott, and the Finance Subcommittee (FSC), chaired by Professor Brian Lake. More detail of the Society finances will be provided in the Treasurer's Report.

Our independent examiners at Sutton McGrath Hartley review the accounts to ensure we meet the requirements of the Charity Commission .

This year the Executive Committee have considered a proposal to increase the membership fees from January 2023. The proposal will be provided by the Treasurer, and this will be considered at the AGM.

One key area to highlight regarding our finances is that donations this year have been very encouraging: the Society received £11,250 in 2021, with a further £7,750 since January this year giving a total of £18,800 for 21/22. The donations help support the work of the Society and we are extremely grateful for this support.

Donating companies for this period were AstraZeneca, ApconiX, Charles River Laboratories, Delphic HSE, GlaxoSmithKline, Syngenta, and Unilever. My thanks to all those companies who have supported the BTS through these generous donations this year which allow the Executive Committee to support many initiatives including the Congress, webinars, scholarships, and bursaries.

My thanks also to those companies who have supported the Congress which include: ApconiX, Bibra, Toxicology Advice and Consulting Ltd , Cyprotex, National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), Oxford University Press, Royal Society of Chemistry and Sequani.

The Scientific Subcommittee (SSC) which is led by Drs Jason Gill (Chair) and Lesley Reeve (Vice-Chair) has been as proactive as ever, changing tack from a virtual Annual Congress to a face to face Annual Congress given the lifting of restrictions due to the pandemic which takes time and energy, and I am pleased to report that the Congress this year is of the same high standard as ever.

The 2021 Congress could not be delivered as a face to face meeting in April due to the Pandemic, but the Hybrid meeting was a success and Dr Gill will provide more details in his report. I am, however, pleased that the 2022 Congress is being delivered as an in person meeting at The Newcastle Hilton, Gateshead.

As part of the SSC there are a number of Speciality groups. It is a pleasure to report that the Subspeciality sections have made a significant contribution to the Society and this year is no exception The Speciality Sections are thriving and include:

My thanks to all the co-ordinators for their hard work with engaging with members and supporting the Society. Several of the Speciality Sections are providing symposia at this year's Congress. Each of the Speciality Sections have also provided networking meetings which started in October 2020.

Dr Miriam Jacobs chaired a successful two day workshop in November on "An Awareness Event: Current Status of New Approach Methodologies (NAMs) for Regulatory Purposes". This event aimed to increase awareness and understanding of current and near future international regulatory developments for NAMs for chemical hazard and human risk assessment. The event addressed the BTS and IGHRC training requirements in raising awareness and understanding of the current status of the internationally-accepted regulatory science basis.

The Society has several Prizes and Travel Scholarships available so please do look at what is on offer at https://www.thebts.org/events-2/awards-and-prizes/.

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The British Toxicology Society

President's Report for the Year Ended 31 December 2021

The Education, Training and Career Development Subcommittee (ETCD), chaired by Dr Tina Mehta, were able to provide the Continuing Education Programme (CEP) virtually in 2021. The topic, which was well received, was "COVID-19 repurposing therapies and vaccines". The CEP sessions are available as audio recordings to our members on the BTS website.

This year the CEP is on a very topical area "Risk Assessments - Across the Sectors":

The ETCD have also been promoting the mentoring scheme to the membership which is free. Senior toxicologists who are willing to provide individual career advice to other members are listed on the website. It has been suggested that some senior members might also benefit from opportunities to being mentored-known as Reverse Mentoring where a member in their early career enters into a "professional friendship" with someone more senior. For more information, please see http://www.thebts.org/membership/mentoring/

Although the Royal Society of Biology Careers Fair were not available as a face to face event this year there was a virtual meeting in November and members of the BTS ETCD subcommittee provided support to members for careers. The ECTD are currently in the process of working with an external organisation to improve the information provided on career opportunities in Toxicology on the BTS website.

The Communication Subcommittee (CSC), chaired by Dr David Woolley , has maintained communication channels with the membership through initiatives such as the Ambassadors Scheme (led by Dr Kirsti Hornigold), the NewsFeed (Editorial Team: Drs Guy Healing, David Woolley, Rani Ghosh and David Jones) and promoting social media channels (Drs Malgorzata.Kurzawa-Zegot and Kemal Haque).

We also welcomed Dr Kirsti Hornigold, MRC Toxicology Unit, University of Cambridge, who has taken on the role of Lead Ambassador Co-ordinator for the Society. This role is the focal point between BTS Ambassadors and the BTS Executive Committee and will be to help the BTS build, support, and improve its network of Ambassadors. The BTS Ambassador scheme aims to deliver and promote the Society's vision and objectives for the science of toxicology at a local level. Kirsti will be a member of the Communication Subcommittee (CSC) and work closely with David Woolley who chairs the CSC. Kirsti will be looking forward to speaking with members about the Ambassador Scheme over the next few months. In the meantime, if your company or institution does not have an Ambassador, please contact bts@execbs.com to discuss your interest. Further information can be found here. If you would like to get in touch with your nearest ambassador to find out more about the BTS or to run a local meeting contact bts@execbs.com

Regional meetings for local networking have also been delivered virtually which have been promoted and organised by the BTS Ambassadors. Dr David Woolley co-ordinated the Ambassador's Scheme and my thanks to you, David and the Ambassadors for supporting the Society in so many ways. As normality returns there will be opportunities to host additional local meetings in the coming year and if you are looking to organise a meeting, grants of up to £250 are available from the BTS to cover meeting costs and refreshments.

Drs Malgorzata.Kurzawa-Zegot and Kemal Haque have been working behind the scenes to promote the various social media platforms the Society uses, so if you are not already on the LinkedIn platforms or Twitter, please do consider these outlets to promote the work of the BTS. Our Twitter account is @BritToxSoc so do please use it to promote the Society. The BTS also has a LinkedIn page and this can be accessed through the following link: https://www.thebts.org/news/bts-joins-linkedin/

In the past year, the Public Communication Steering Team chaired by Dr Phil Botham has produced several public statements which provide authoritative, educational comment on a toxicology related topic of interest. The full list of public statements on our website are:

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The British Toxicology Society

President's Report for the Year Ended 31 December 2021

Drs Bryony Ross and Trudy Knight joined the Public Communications Steering Team in 2021 following interviews for these positions.

The Executive Committee also recognised that our early career scientists have a particular role to play, both within the BTS and in the broader scientific community. Having looked at our membership of subcommittees and the Executive Committee it was felt that that the voices of those at an early stage in their career were under-represented. We have now established the 'Network for Early Stage Toxicologists' (NEST) as an opt-in community, making best use of social media, as well as face to face networking opportunities at congresses, to build a community and feed ideas into the Executive Committee to support those at an early stage of their career.

The NEST, chaired by Nevine Amer, University of Hertfordshire, is tasked with coordinating early career networking, as well as career's outreach in universities, giving scientific input to help shape the BTS Congress, and also providing early career representation on the various subcommittees of the Society and in particular Scientific, Communication and Education, Training and Career Development (ETCD).

NEST have been very active in organising Podcasts with some of our established toxicologists and these will be an addition to the website in the months to come.

From April 2022, Nevine will also be a member of the Nominations Subcommittee to ensure our early stage toxicologists are represented.

We were also pleased that in this 50th year we are also able to celebrate the first recipient of the Malcom Blackwell Award to Dr Gillian Conway, Swansea University. This award in recognition of an individual deemed inspirational, impactful and a role model to members of the NEST. Dr Conway will be presenting her lecture, "Using In Vitro 3D Liver Models for the Development of Hazard Assessment Protocols Following Exposure to Engineered Nanomaterials" at the Annual Congress on Monday 4th April at 17.45 where she will receive the award and deliver the NEST invitation lecture.

As the BTS is a registered charity, committee members of the BTS are volunteers and without their willing help, the Society would simply not be able to exist. There are always opportunities for members to get involved. If you are interested in helping the Society by being a member of the Executive Committee or the subcommittees, please contact bts@execbs.com. Even if no suitable opportunity is available now, it is very helpful for planning purposes, to be aware of expressions of interest for roles on committees from our members.

BTS Website Update

The Executive Committee decided, based on feedback from members, that the website needed an overhaul. A tendering process was undertaken, and Insights Design and Printing Ltd undertook this project and the website will be launched following the AGM. My thanks to Dr Fiona Sewell for leading on this project.

Toxicology Research

The Official Journal of the BTS, Toxicology Research, now published by Oxford University Press (OUP), has increased its impact fact to 3.524. We are delighted to work with OUP and its Editor-in-Chief, Professor Heather Wallace. We are happy to have negotiated a great discount for our members for online subscriptions to the journal. The cost to BTS members is just £60, which is less than 4% of the institutional subscription. If you would like to take up this offer, you can apply at: https://academic.oup.com/toxres/subscribe. Professor Wallace is also a co-opted member of the Executive Committee.

I am also pleased to report that the OUP are supporting the BTS with a prize for the best student communication to the value of £100.00 of OUP books.

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The British Toxicology Society

President's Report for the Year Ended 31 December 2021

Interaction with other Societies

One of the strategic objectives of the BTS is to promote interactions with other scientific societies and organisations to meet our vision to "drive excellence in toxicology". Our work with other Learned Societies and Professional Bodies ensures we have a voice, feed into consultations applicable to the discipline of Toxicology and have seat at the table to lobby the Government where required. It is a pleasure to work closely with the following organisations:

The Executive Committee are looking to establish closer links with other Professional Bodies and Learned Societies such as the Society of Environmental Toxicology and Chemistry (SETAC).

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The British Toxicology Society

President's Report for the Year Ended 31 December 2021

In Memoriam

As we come to the end of this Society year 2021/22, we should take a moment to think of those members who passed away. The following members and gave so much to the Society, its members, and the science of toxicology namely: - Dr Frank Sullivan

Gratias Tibi

Finally, I would like to thank a few people who have worked extremely hard on your behalf, the membership.

Firstly, thanks to our immediate Past President and Chair of NSC, Dr Chris Powell, for his sterling leadership over the two years 2020-20202. Chris has been supporting the Society through several roles and in total has provided 16 years' service.

My thanks to Dr Carol Courage for her sterling work as the General Secretary (2021-2022). A role that is key to the Society and one that requires stamina and diplomacy. Carol has served as the General Secretary keeping the Society and the Executive Committee on track: not an easy task! Carol, you have been a fantastic General Secretary and my thanks for the support you have given me as President and the support given to the Society.

Dr Tina Mehta (2016-2022) leaves the role as Chair of the ETCD Subcommittee and An ordinary member of the Executive Committee. Tina has served in this role and as an ordinary member since 2016. My thanks to you, Tina, for your support of the Society in your various roles.

Dr Jason Gill (2018-2022) leaves the role as Chair of the Scientific Subcommittee of the Executive Committee. Jason has served in this role since 2018. My thanks to you, Jason, for your support to the Society through chairing the Scientific Subcommittee during a difficult time due to the Pandemic.

I would also like to thank Dr Guy Healing who steps down from the NewsFeed Editorial Team after 6 years. Thank you, Guy, for your contribution to the Team and to the Society in the many roles you have held including that of the Treasurer.

Finally, to the Officers and members of the Executive Committee who give their skills and time freely to help run the Society and promote Toxicology my thanks to you all for the support you have given the Society and to me personally as President over the last two years.

Thanks are also due to the Chairs, Co-ordinators, members of the BTS subcommittees and Speciality Sections, the Editorial Team and Ambassadors for your support also.

As ever, I am extremely grateful to our secretariat Executive Business Support Ltd (EBS) for the administrative support provided to the Society and in particular to Gail Ryan, Steve Hewitt, Freya-Louise Andrews and Shona Hunt for their valued assistance in the support given to the BTS and to me personally.

Finally, my thanks to you, the members, for your support and loyalty to the BTS.

Professor Shirley Price, President of the BTS

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The British Toxicology Society

Operating and Financial Review for the Year Ended 31 December 2021

Overview

BTS finances remain in an adequate state. The BTS has a policy in alignment with the rules of the Charity Commission to set aside unrestricted financial reserves equivalent to up to 30 months of expenditure to ensure coverage of operating costs during times of financial distress. Expenditure during 2021 averaged £7.7k/month, which equates to £230k over a 30-month period. The total funds carried forward from 2021 were £379k and so the Society is currently meeting this obligation.

Changes to Standard Financial Operations

A minor change was implemented during this reporting period to improve accountability and transparency; a small value purchase order system was implemented to improve control over spending and provide a contractual framework for suppliers.

Contribution to Meetings, Events, Awards and Training

The annual congress was run as a virtual meeting in 2021. Overhead costs associated with virtual meetings are significantly lower than traditional meetings and so this activity generated a modest surplus of £5,482. Normally, the Society would expect to subsidise the annual congress by ~ £5k - 20k.

The Society contributed £993 to support scientific meetings (e.g., webinars) and provided £3,022 in awards (e.g., Early Career Prize, Patton Prize, Studentships). In addition, £1,860 was invested in a package of Equality, Diversity and Inclusion measures (e.g., training and reviews of web content & public documents) to ensure compliance of the Society with legislative obligations.

Subscriptions to Other Learned Societies

Institutional subscriptions to other societies (e.g., Eurotox, IUTOX, Royal Society of Biology, etc.) totalled £6,505. Such memberships provide additional benefits to BTS members and further consolidates the BTS as an internationally recognised professional body.

Donations to BTS

Corporate donations to the Society were very generous under the circumstances and are discussed in more detail in the President's AGM report. For the reporting period January - December 2021, a total of £11,250 was receipted to support the general work of the BTS. A further £4,899 was received towards the cost of the virtual congress. I would like to take this opportunity to personally thank all those institutions and companies who have continue to support the Society during the pandemic.

Advertising Income

Income from advertising on the BTS website marginally increased to £8,150 during this financial year. Advertising costs and associated policy are to be reviewed in 2022 to ensure that the cost of advertising (and policies relating to the placement of notifications) continue to provide membership benefit as well as meeting the financial requirements of the Society.

Surplus

This year was significantly impacted by the COVID pandemic, during which the activities of the Society were significantly curtailed by HM Government restrictions. For example, it was not possible to hold the Annual Congress, which normally runs at a loss of £5 - £20k. In contrast, income generated through membership fees remained relatively static. Consequently, there was a second, consecutive period of unexpected surplus. It should be noted that this surplus is primarily the result of decreased activity associated with the COVID pandemic and so represents an aberration from the normal finances of the Society. A plan to spend this surplus for the benefit of our members has been incorporated into the 2022 budget.

Future (2022) Budget

The temporary reduction in BTS activities due to the on-going pandemic has resulted in a financial surplus for two consecutive years. As the primary aim of the BTS is to provide benefits for its members, it has provisionally been agreed to incorporate the following additional expenditure into the 2022 budget, which is forecast to result in an operational deficit of £31,055 for the period January - December 2022 (excluding any subsidy to the BTS annual congress).

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The British Toxicology Society

Operating and Financial Review for the Year Ended 31 December 2021

a. Project Co-ordinator position (£25k).

The main objective for the project coordinator role will be to develop a training schedule to cover the principles required to develop a risk-based scientist across the discipline of safety sciences. This information will be shared with stakeholders and educational providers to ensure that the UK remains at the forefront of delivering relevant training and education for future generations of toxicologists.

Prof R P Chilcott BTS Treasurer

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The British Toxicology Society

Report of the Trustees for the Year Ended 31 December 2021

The trustees who are also directors of the charity for the purposes of the Companies Act 2006, present their report with the financial statements of the charity for the year ended 31 December 2021. The trustees have adopted the provisions of Accounting and Reporting by Charities: Statement of Recommended Practice applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS 102) (effective 1 January 2019).

OBJECTIVES AND ACTIVITIES

Objectives and significant activities

The Society is established for the promotion and advancement, for the public benefit, of education in the science of toxicology. In deciding the aims and activities of the society, the trustees have paid due regard to the guidance issued by the Charity Commission on public benefit. Toxicology is the science of disease induced by chemicals present in the diet, medicines, and in the environment. The British Toxicology Society (BTS) is a leading international toxicology society, based on the highest quality science, and promotes the advancement, communication and understanding of the scientific disciplines necessary to foster public health and environmental safety.

STRUCTURE, GOVERNANCE AND MANAGEMENT Governing document

The Society is a company limited by guarantee and the liability of members is limited to an amount not exceeding £1. It is exempt under Section 60 of the Companies Act 2006 from the requirement to use the word 'Limited' in its title. The Society is governed by the Memorandum and Articles of Association. It is registered with the Charities Commission, number 286197, and no liability to taxation arises.

The Executive Committee are Directors for the purpose of company law and Trustees for the purpose of charity law. Directors/Trustees are appointed by the Society's members at the Annual General Meeting. When a Trustee retires, the Executive Committee nominates new Trustees. Additional nominations may be made by the membership, provided they are signed by six members of the Society.

Informal induction procedures are in place for new Trustees, conducted by an existing member of the Executive Committee and they are also provided with relevant documentation to formally advise and inform them of the Society's constitution and objectives and also their duties and responsibilities as a trustee.

One third of the Executive Committee ordinary members retire each year in rotation but are then eligible for re-election. The society is organised so that the Trustees, in the form of the Executive Committee, meet regularly, usually on a quarterly basis, to manage its affairs. There are also sub-committees which are responsible for advising and researching the various activities and development of the Society, who report to the Executive Committee. Statutes for the workings of the various sub-committees are continually being revised and updated to ensure that the terms of reference are clearly defined and the ways of working are consistent. This also enables transparency of committee elections and duration of membership, while allowing the committees to work to agreed aims, backed up by comprehensive set of Standard Operating Procedures for the Society.

The trustees have assessed the major risks to which the Society is exposed, in particular those related to the operations and finances of the Society, and are satisfied that systems are in place to mitigate exposure to major risks. All of the officers and members who serve on the Society's committees are unpaid. They are entitled to be reimbursed for any out of pocket expenses incurred in attending meetings.

No related parties, related party transactions, beneficial relationships or conflicts of interest requiring disclosure by the Charities' or Companies' Acts existed during the year.

Attendance by Executive Committee members has been reasonable throughout the year. The co-opted members continue to provide liaison with the relevant Sub-Committees and Speciality Sections.

The day to day administration of the Society is undertaken by an outside agency on a fee basis.

REFERENCE AND ADMINISTRATIVE DETAILS Registered Company number

01676618 (England and Wales)

Registered Charity number

286197

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The British Toxicology Society

Report of the Trustees for the Year Ended 31 December 2021

Registered office

Executive Business Support Limited City Wharf Davidson Road Lichfield Staffordshire WS14 9DZ

Trustees

Dr D J Benford Toxicologist (resigned 12/4/2021) Dr J Gill Reader In Molecular Therapeutics (resigned 4/4/2022) Professor B G Lake Toxicologist Dr E Marczylo Toxicologist Dr E Martin Toxicologist (resigned 12/4/2021) Dr D R Mason Toxicological Safety Dr J Mehta Toxicologist (resigned 4/4/2022) Dr C J Powell Histopathologist (resigned 4/4/2022) Professor S C Price Professor Of Toxicology Dr J Thompson Physician Dr F Sewell Programme Manager Dr P A Botham Toxicologist Dr L M Reeve Toxicologist Dr C Courage (appointed 12/4/2021) (resigned 4/4/2022) Prof. R Chilcott (appointed 12/4/2021) Dr I Copple (appointed 4/4/2022) Dr B Ross (appointed 4/4/2022) Dr H Matar (appointed 4/4/2022)

Company Secretary Professor S C Price

Independent Examiner

Jonathon Dickens ACA Sutton McGrath Hartley 5 Westbrook Court Sharrowvale Road Sheffield South Yorkshire S11 8YZ

Approved by order of the board of trustees on 28 September 2022 and signed on its behalf by:

Prof. R Chilcott - Trustee

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Independent Examiner's Report to the Trustees of The British Toxicology Society

Independent examiner's report to the trustees of The British Toxicology Society ('the Company')

I report to the charity trustees on my examination of the accounts of the Company for the year ended 31 December 2021.

Responsibilities and basis of report

As the charity's trustees of the Company (and also its directors for the purposes of company law) you are responsible for the preparation of the accounts in accordance with the requirements of the Companies Act 2006 ('the 2006 Act').

Having satisfied myself that the accounts of the Company are not required to be audited under Part 16 of the 2006 Act and are eligible for independent examination, I report in respect of my examination of your charity's accounts as carried out under section 145 of the Charities Act 2011 ('the 2011 Act'). In carrying out my examination I have followed the Directions given by the Charity Commission under section 145(5) (b) of the 2011 Act.

Independent examiner's statement

I have completed my examination. I confirm that no matters have come to my attention in connection with the examination giving me cause to believe:

  1. accounting records were not kept in respect of the Company as required by section 386 of the 2006 Act; or

  2. the accounts do not accord with those records; or

  3. the accounts do not comply with the accounting requirements of section 396 of the 2006 Act other than any requirement that the accounts give a true and fair view which is not a matter considered as part of an independent examination; or

  4. the accounts have not been prepared in accordance with the methods and principles of the Statement of Recommended Practice for accounting and reporting by charities (applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS 102)).

I have no concerns and have come across no other matters in connection with the examination to which attention should be drawn in this report in order to enable a proper understanding of the accounts to be reached.

Jonathon Dickens ACA Sutton McGrath Hartley 5 Westbrook Court Sharrowvale Road Sheffield South Yorkshire S11 8YZ

29 September 2022

Page 13

The British Toxicology Society

Statement of Financial Activities for the Year Ended 31 December 2021

Unrestricted
Restricted
fund
funds
Notes
£
£
INCOME AND ENDOWMENTS FROM
Donations and legacies
65,654
-
Charitable activities
Annual Congress
25,564
-
Annual Congress trade exhibition
3,375
-
PATDD, ACT joint meetings, webinars and online
events
20,278
-
Other trading activities
2
9,890
-
Investment income
3
1,524
21
Total
126,285
21
EXPENDITURE ON
Raising funds
4
29,290
-
Charitable activities
5
Annual Congress
11,680
-
PATDD, ACT joint meetings, webinars and online
events
22,286
-
Donations and subscriptions to other societies
6,607
-
Travel bursaries and early career support
3,124
-
Other
18,871
-
Total
91,858
-
NET INCOME
34,427
21
RECONCILIATION OF FUNDS
Total funds brought forward
345,064
9,962
TOTAL FUNDS CARRIED FORWARD
379,491
9,983
2021
Total
funds
£
65,654
25,564
3,375
20,278
9,890
1,545
126,306
29,290
11,680
22,286
6,607
3,124
18,871
91,858
34,448
355,026
389,474
2020
Total
funds
£
69,114
-
-
15,786
10,255
2,205
97,360
28,179
23,286
4,257
6,990
1,599
14,451
78,762
18,598
336,428
355,026

The notes form part of these financial statements

Page 14

The British Toxicology Society

Balance Sheet

31 December 2021

Unrestricted
Restricted
fund
funds
Notes
£
£
CURRENT ASSETS
Debtors
9
28,370
-
Cash at bank
368,595
9,983
396,965
9,983
CREDITORS
Amounts falling due within one year
10
(17,474)
-
NET CURRENT ASSETS
379,491
9,983
TOTAL ASSETS LESS CURRENT LIABILITIES
379,491
9,983
NET ASSETS
379,491
9,983
FUNDS
11
Unrestricted funds
Restricted funds
TOTAL FUNDS
2021
Total
funds
£
28,370
378,578
406,948
(17,474)
389,474
389,474
389,474
379,491
9,983
389,474
2020
Total
funds
£
41,391
387,799
429,190
(74,164)
355,026
355,026
355,026
345,064
9,962
355,026

The charitable company is entitled to exemption from audit under Section 477 of the Companies Act 2006 for the year ended 31 December 2021.

The members have not required the company to obtain an audit of its financial statements for the year ended 31 December 2021 in accordance with Section 476 of the Companies Act 2006.

The trustees acknowledge their responsibilities for

The notes form part of these financial statements

continued...

Page 15

The British Toxicology Society

Balance Sheet - continued

31 December 2021

These financial statements have been prepared in accordance with the provisions applicable to charitable companies subject to the small companies regime.

The financial statements were approved by the Board of Trustees and authorised for issue on 28 September 2022 and were signed on its behalf by:

R Chilcott - Trustee

S C Price - Trustee

The notes form part of these financial statements

Page 16

The British Toxicology Society

Notes to the Financial Statements for the Year Ended 31 December 2021

1. ACCOUNTING POLICIES

Basis of preparing the financial statements

The financial statements of the charitable company, which is a public benefit entity under FRS 102, have been prepared in accordance with the Charities SORP (FRS 102) 'Accounting and Reporting by Charities: Statement of Recommended Practice applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS 102) (effective 1 January 2019)', Financial Reporting Standard 102 'The Financial Reporting Standard applicable in the UK and Republic of Ireland' and the Companies Act 2006. The financial statements have been prepared under the historical cost convention.

Going concern

There are no material uncertainties about the charity's ability to continue.

The trustees' assessment of the risks associated with Brexit and the pandemic are detailed in the President's report.

Financial reporting standard 102 - reduced disclosure exemptions

The charitable company has taken advantage of the following disclosure exemptions in preparing these financial statements, as permitted by FRS 102 'The Financial Reporting Standard applicable in the UK and Republic of Ireland':

Income

All incoming resources are included in the statement of financial activities when entitlement has passed to the charity; it is probable that the economic benefits associated with the transaction will flow to the charity and the amount can be reliably measured. The following specific policies are applied to particular categories of income:

Expenditure

Expenditure is recognised on an accruals basis as a liability is incurred. Expenditure includes any VAT which cannot be fully recovered, and is classified under headings of the statement of financial activities to which it relates:

continued...

Page 17

The British Toxicology Society

Notes to the Financial Statements - continued for the Year Ended 31 December 2021

1. ACCOUNTING POLICIES - continued

Expenditure

All costs are allocated to expenditure categories reflecting the use of the resource. Direct costs attributable to a single activity are allocated directly to that activity. Shared costs are apportioned between the activities they contribute to on a reasonable, justifiable and consistent basis.

Taxation

The charity is exempt from corporation tax on its charitable activities.

Fund accounting

Unrestricted funds can be used in accordance with the charitable objectives at the discretion of the trustees.

Restricted funds can only be used for particular restricted purposes within the objects of the charity. Restrictions arise when specified by the donor or when funds are raised for particular restricted purposes.

Further explanation of the nature and purpose of each fund is included in the notes to the financial statements.

2. OTHER TRADING ACTIVITIES

Unrestricted
Restricted
funds
funds
£
£
Website advertising
8,150
-
OUP / RSC Journal income
1,740
-
9,890
-
INVESTMENT INCOME
Unrestricted
Restricted
funds
funds
£
£
Deposit account interest
1,524
21
2021
Total
funds
£
8,150
1,740
9,890
2021
Total
funds
£
1,545
2020
Total
funds
£
7,875
2,380
10,255
2020
Total
funds
£
2,205

3. INVESTMENT INCOME

continued...

Page 18

The British Toxicology Society

Notes to the Financial Statements - continued for the Year Ended 31 December 2021

4. RAISING FUNDS

Raising donations and legacies

Unrestricted
Restricted
funds
funds
£
£
Bank charges
852
-
EBS - membership processing
10,512
-
Membership discount
-
-
Support costs
3,516
-
14,880
-
Other trading activities
Unrestricted
Restricted
funds
funds
£
£
EBS- website management
9,426
-
ACT webinars
805
-
Bank charges
61
-
Publicity materials
600
-
Support costs
3,518
-
14,410
-
Aggregate amounts
29,290
-
2021
Total
funds
£
852
10,512
-
3,516
14,880
2021
Total
funds
£
9,426
805
61
600
3,518
14,410
29,290
2020
Total
funds
£
1,003
8,121
61
8,782
17,967
2020
Total
funds
£
5,894
-
35
600
3,683
10,212
28,179

5. CHARITABLE ACTIVITIES COSTS

Annual Congress
PATDD, ACT joint meetings, webinars
and online events
Donations and subscriptions to other
societies
Travel bursaries and early career
support
Support
Direct
costs (see
Costs
note 6)
£
£
11,680
-
17,594
4,692
5,435
1,172
1,952
1,172
36,661
7,036
Totals
£
11,680
22,286
6,607
3,124
43,697

continued...

Page 19

The British Toxicology Society

Notes to the Financial Statements - continued for the Year Ended 31 December 2021

6. SUPPORT COSTS

Management
£
Raising donations and
legacies
-
Other trading activities
-
Other resources expended
7,823
PATDD, ACT joint meetings,
webinars and online events
-
Donations and
subscriptions to other
societies
-
Travel bursaries and early
career support
-
7,823
Information
Governance
Finance
technology
costs
£
£
£
3,516
-
-
3,518
-
-
-
3,491
7,557
4,692
-
-
1,172
-
-
1,172
-
-
14,070
3,491
7,557
Totals
£
3,516
3,518
18,871
4,692
1,172
1,172
32,941

7. TRUSTEES' REMUNERATION AND BENEFITS

There were no trustees' remuneration or other benefits for the year ended 31 December 2021 nor for the year ended 31 December 2020.

Trustees' expenses

2021
£
Trustees' expenses
426
8.
COMPARATIVES FOR THE STATEMENT OF FINANCIAL ACTIVITIES
Unrestricted
Restricted
fund
funds
£
£
INCOME AND ENDOWMENTS FROM
Donations and legacies
69,114
-
Charitable activities
PATDD, ACT joint meetings, webinars and
online events
15,786
-
Other trading activities
10,255
-
Investment income
2,151
54
Total
97,306
54
EXPENDITURE ON
Raising funds
28,179
-
Charitable activities
Annual Congress
23,286
-
PATDD, ACT joint meetings, webinars and
online events
4,257
-
Donations and subscriptions to other
societies
6,990
-
2020
£
341
Total
funds
£
69,114
15,786
10,255
2,205
97,360
28,179
23,286
4,257
6,990

continued...

Page 20

The British Toxicology Society

Notes to the Financial Statements - continued for the Year Ended 31 December 2021

8.
COMPARATIVES FOR THE STATEMENT OF FINANCIAL ACTIVITIES - continued
Unrestricted
Restricted
fund
funds
£
£
Travel bursaries and early career support
1,599
-
Other
14,451
-
Total
78,762
-
NET INCOME
18,544
54
RECONCILIATION OF FUNDS
Total funds brought forward
326,520
9,908
TOTAL FUNDS CARRIED FORWARD
345,064
9,962
9.
DEBTORS: AMOUNTS FALLING DUE WITHIN ONE YEAR
2021
£
Debtors
5,540
Prepayments &
accrued income
22,830
28,370
10.
CREDITORS: AMOUNTS FALLING DUE WITHIN ONE YEAR
2021
£
Trade creditors
4,365
Accruals & prepaid income
13,109
17,474
Total
funds
£
1,599
14,451
78,762
18,598
336,428
355,026
2020
£
114
41,277
41,391
2020
£
7,647
66,517
74,164

continued...

Page 21

The British Toxicology Society

Notes to the Financial Statements - continued for the Year Ended 31 December 2021

11. MOVEMENT IN FUNDS

MOVEMENT IN FUNDS
Net
movement At
At 1/1/21 in funds 31/12/21
£ £ £
Unrestricted funds
General fund 345,064 34,427 379,491
Restricted funds
Barnes fund 811 1 812
Paton fund 3,768 2 3,770
Norman Aldridge fund 5,383 18 5,401
9,962 21 9,983
TOTAL FUNDS 355,026 34,448 389,474
Net movement in funds, included in the above are as follows:
Unrestricted funds Incoming
resources
£
Resources
expended
£
Movement
in funds
£
General fund 126,285 (91,858) 34,427
Restricted funds
Barnes fund 1 - 1
Paton fund 2 - 2
Norman Aldridge fund 18 - 18
21 - 21
TOTAL FUNDS 126,306 (91,858) 34,448
Comparatives for movement in funds
Unrestricted funds At 1/1/20
£
Net
movement
in funds
£
At
31/12/20
£
General fund 326,520 18,544 345,064
Restricted funds
Barnes fund 808 3 811
Paton fund 3,759 9 3,768
Norman Aldridge fund 5,341 42 5,383
9,908 54 9,962
TOTAL FUNDS 336,428 18,598 355,026

continued...

Page 22

The British Toxicology Society

Notes to the Financial Statements - continued for the Year Ended 31 December 2021

11. MOVEMENT IN FUNDS - continued

Comparative net movement in funds, included in the above are as follows:

Incoming Resources Movement Movement
resources expended in funds
£ £ £
Unrestricted funds
General fund 97,306 (78,762) 18,544
Restricted funds
Barnes fund 3 - 3
Paton fund 9 - 9
Norman Aldridge fund 42 - 42
54 - 54
TOTAL FUNDS 97,360 (78,762) 18,598

Restricted funds comprise donations given to provide lecture awards, travel grants and support to early career toxicologists. Awards are made by the trustees on an alternate year basis.

12. RELATED PARTY DISCLOSURES

There were no related party transactions.

Page 23

The British Toxicology Society

Detailed Statement of Financial Activities for the Year Ended 31 December 2021

Unrestricted
Restricted
funds
funds
£
£
INCOME AND ENDOWMENTS
Donations and legacies
Donations
11,250
-
Subscriptions
54,404
-
65,654
-
Other trading activities
Website advertising
8,150
-
OUP / RSC Journal income
1,740
-
9,890
-
Investment income
Deposit account interest
1,524
21
Charitable activities
Annual Congress delegates
20,665
-
Annual Congress donations
4,899
-
Annual Congress exhibitors and trade stands
3,375
-
PATDD & ACT joint meetings & webinars
20,278
-
49,217
-
Total incoming resources
126,285
21
EXPENDITURE
Raising donations and legacies
Bank charges
852
-
EBS - membership processing
10,512
-
Membership discount
-
-
11,364
-
Other trading activities
EBS- website management
9,426
-
ACT webinars
805
-
Bank charges
61
-
Publicity materials
600
-
10,892
-
Charitable activities
Publicity
19
-
Carried forward
19
-
2021
Total
funds
£
11,250
54,404
65,654
8,150
1,740
9,890
1,545
20,665
4,899
3,375
20,278
49,217
126,306
852
10,512
-
11,364
9,426
805
61
600
10,892
19
19
2020
Total
funds
£
14,000
55,114
69,114
7,875
2,380
10,255
2,205
-
-
-
15,786
15,786
97,360
1,003
8,121
61
9,185
5,894
-
35
600
6,529
-
-

This page does not form part of the statutory financial statements

Page 24

The British Toxicology Society

Detailed Statement of Financial Activities for the Year Ended 31 December 2021

Unrestricted
Restricted
funds
funds
£
£
Charitable activities
Brought forward
19
-
Insurance
-
-
Entertainment
30
-
Speakers' expenses
2,068
-
Joint meeting costs
-
-
Bank charges
37
-
EBS management fee
25,034
-
EBS travel expenses
-
-
EBS processing fees
1,516
-
Eurotox subscription
1,690
-
Understanding Animal Research
266
-
Society of Biology
690
-
Iutox International
2,759
-
Science workshops
600
-
Early career prizes
420
-
Travel bursary
-
-
Studentship
1,208
-
Oral presentation prize
100
-
Recognition awards
224
-
36,661
-
Support costs
Management
Postage and stationery
269
-
EBS- trustee support
7,554
-
7,823
-
Finance
EBS- bookkeeping & finance
14,070
-
Information technology
EBS- licences & IT support
3,491
-
Members survey
-
-
3,491
-
Governance costs
Meeting expenses - trustees
426
-
Accountancy fees
7,026
-
Company secretarial and AGM
13
-
Meeting expenses- non trustees
92
-
Meeting expenses- room hire
-
-
7,557
-
2021
Total
funds
£
19
-
30
2,068
-
37
25,034
-
1,516
1,690
266
690
2,759
600
420
-
1,208
100
224
36,661
269
7,554
7,823
14,070
3,491
-
3,491
426
7,026
13
92
-
7,557
2020
Total
funds
£
-
787
150
-
586
123
19,032
119
1,864
1,731
264
690
3,048
-
-
372
-
-
-
28,766
534
6,317
6,851
11,731
3,000
5,100
8,100
341
6,601
34
606
18
7,600

This page does not form part of the statutory financial statements

Page 25

The British Toxicology Society

Detailed Statement of Financial Activities for the Year Ended 31 December 2021

Unrestricted
Restricted
funds
funds
£
£
Total resources expended
91,858
-
Net income
34,427
21
2021
Total
funds
£
91,858
34,448
2020
Total
funds
£
78,762
18,598

This page does not form part of the statutory financial statements

Page 26