2024-07-31-accounts

The International Glaucoma Association Limited operating as Glaucoma UK Trustees, Annual Report and Financial Statements for the year ending 31 July 2024 ears ill. Glaucoma UK Celebrating 50 years 1974 - 2024

Contents T4

Glaucoma UK Trustees, Annual Report 2023 - 24 Contents 04 Welcome from the Chair 42 Financial review 06 A message from the CEO 46 Trustees, advisors and staff 08 Our vision and priorities 48 Structure and management 10 Our Theory of Change 12 Strategic report: what we achieved in 2023-24 12 Priority I . Raising awareness 16 Priority 2: Providing support 22 Priority 3: Funding research 30 Priority 4: Influencing policy and practice 54 Statement of trustee responsibilities 56 Independent auditors, report 60 Financial statements 34 Fundraising review 40 Looking forward

Welcome from the Chair Welcome from the Chair I'm delighted to be sharing our Trustees, Annual Report for 2023-24 with you. It has certainly been a memorable 12 months as we have celebrated our 50th anniversary. I feel very fortunate to be the incumbent Chair as Glaucoma UK reaches this highly Significant milestone, and I want to take a moment to extend my thanks to all those who have preceded me. The charity, as it stands today, owes a debt of gratitude to the commitment and vision of the previous chairpersons, trustees and staff members who worked 50 hard to improve the lives of people living with glaucoma. Principal actor among that cast is, of course, our founder Ronald Pitts-crick, who established the charity in 1974 and dedicated 30 years of his life to leading its work. Although much has changed since that time - including the charity's name - the passion to bring an end to preventable sight loss from glaucoma remain5 unabated. To honour our founder in this anniversary year, it has been a great pleasure to introduce the new Pitts-crick Research Fellowship. This initiative offers an excellent opportursity to support an ambitious researcher over three years as they work to further our understanding of the disease.

Glaucoma UK Trustees, Annual Report 2023 - 24 Another key feature of our anniversary celebrations has been a deepened focus on what it means to be a member of Glaucoma UK. The team have been working harder than ever to ensure that our members feel part of a dynamic and mutually supportive community. We hope everyone who enjoyed our regular Insight magazine, called our helpline, attended our webinars or lectures, took part in a support group, received training or sought advice from one of our Buddy volunteers will agree that we achieved that goal. The country has seen considerable change during the year, with a new government and an ever more varied range of diagnostic and treatment options for glaucoma patients to navigate. Against that backdrop, it's essential that we offer continuity. advocacy and trusted advice for our members and 5UPPOrters. So, as we enter our second half-century, we will continue working to raise awareness, provide support, fund sight-saving research and influence glaucoma policy and practice. As we tackle this ambitious 'To Do, list, we will be mindful that none of it would be possible without the extraordinary people who fundraise for our charity and those who make voluntary gifts to support our essential work. Your generosity and kindness underpin every achievement you will read about in this report. As such, it is dedicated to you, with our heartfelt thanks. Professor Anthony Kin Consultant Ophthalmologist and Glaucoma UK Chair

A message from the CEO A message from the CEO l echo the Chair's comments about what a privilege it is to find oneself at the helm during Glaucoma UK'S special anniversary year. It is also a huge responsibility. While it is a joy to look back on 50 years of progress, we are keenly aware that we must achieve even more in the future. We must make more people aware of the risk of glaucoma; we must provide even more support in more accessible ways to more people. we must spend more on sight saving research. And - most importantly of all - we must share the voice of our members even more loudly with those responsible for developing and delivering glaucoma care. To make all this happen, we are excited to be embarking on a period of growth. As this report highlights, we have already begun to reap the benefits of a new Head of Research, additional helpline resource and a new team of Training and Engagement Officers who took up permanent roles in all four nations of the UK during theyear. Among those benefits was our highest ever number of helpline enquiries, the be5t-attended UK and Eire Glaucoma Society (UKEGS) Conference in the event's history, the highest ever attendance at our online webinars, the introduction of a new research fellowship and just under 1 million instances of support for people living with glaucoma.

Glaucoma UK Trustees, Annual Report 2023 - 24 We have made a promising start to our ambitious three-year financial plan, which will see us seeking new income streams and drawing on our reserves to maximi5e the reach and impact of our vital sight saving work. Our progress to date is thanks to the wise counsel of our Board of Trustees and the hard work and dedication of my extraordinary colleagues; I hope you enjoy reading about their achievements in this report. 66 We are excited to be embarking on a period of growth Joanne Creighton. Chief Executive Officer . Insight TF4 NTFP 2025 Irfte•1ln8 thepoiv•r gf Ilmmun¢ ty¥te•rn" ian antlbody help *. In5tglatscomaP Page 28 ,J•- Gla uk

Our vision and priorities

Glaucoma UK Trustees. Annual Report 2023 - 24 Our vision and priorities Glaucoma is a complex group of eye diseases that damage the optic nerve and, if left untreated, can lead to irreversible vision loss and even blindness. At Glaucoma UK, our goal is to eliminate preventable glaucoma-related sight loss. Currently, we believe that well over 700,000 people in the UK are affected by glaucoma? yet nearly half are unaware of it due to the frequent lack of early symptom5. The only reliable way to detect glaucoma is through a comprehensive eye examination, but more than a third of UK adults don't attend regular check-ups. The issue is even more pressing in high-risk groups, including individuals facing socio-economic challenges and those of African-caribbean descent, where attendance rates are even lower. Therefore, we are dedicated to raising awareness about the importance of early diagnosis acr055 all communities. Alongside early detection, timely treatment and ongoing monitoring are a150 essential in helping people with glaucoma preserve their vision for life. However, with rising demand and lengthy wait times, much remains to be done to establish a reliable and consistent treatment pathway across the UK, We strive to amplify the voices of those living with glaucoma, so they are heard by healthcare providers, policymakers, and service commissioners. Perhaps our greatest tool in preventing sight loss from glaucoma is research. We aim to understand the causes of glaucoma, how to prevent it, which treatments are most effective, and-ultimately how to cure it. Through our annual funding program, we support research that explores new medical and surgical approaches and innovative treatment models in the hope of finding these answers.

10 Our Theory of Change Our Theory of Change Our Theory of Change sets out the long-term, sustained impact we want our work to have for people living with glaucoma. As a result of our efforts, we want to change the glaucoma care landscape in the following ways: Increased awareness and earlier diagnosis of glaucoma among those who are most at risk. More people are able to live well and maintain sight through equitable and timely access to effective clinical care and pastoral support. We focus on four priority areas in pursuit of these sustained impact goals:

Glaucoma UK Trustees, Annual Report 2023 - 24 11 Priority I: Raising awareness Disseminating clear, accessible, impactful messaging about the risk to individuals. Ensuring professionals are aware of Glaucoma UK'S role in supporting glaucoma care. Priority 2: Providing support Giving accessible and effective advice and information to individuals and their carers. Offering practical and emotional support to help individuals adhere to their treatment regime. Creating and promoting an active and mutually supportive glaucoma community. Priority 3: Supporting research and development Providing funding for high-quality research into glaucoma prevention, diagnosis, treatment and cure. Liaising with corporate bodies to improve glaucoma treatment5 and patient outcomes. Priority 4: Influencing policy and professional practice Advocating for the patient perspective in the design, development and delivery of glaucoma care pathways. Providing relevant and credible information and support for medical professionals.

12 Strategic report Strategic report: what we achieved in 2023-24 Priority I: Raising awareness The f irst step in bringing about an end to glaucoma sight loss is to raise awareness about the disease and the risk to individuals. Our awareness raising campaigns encourage people to have their eyes examined every two years, unless advised otherwise by their healthcare professional. We also want to ensure that people know about our work and the many services we provide to help them manage their glaucoma. We work to raise awareness among eyecare professionals, too. They have an essential role to play in signposting their patients to our charity, so that we can provide the pastoral support that simply cannot happen in the time-strapped clinic environment. Desired outcomes of our efforts to raise awareness include: More people understand why they may be at risk of glaucoma and that it could impact their vision, even without symptoms. More people who are at highest risk of glaucoma seek an eye examination. More professionals are aware of Glaucoma UK and refer people to us for advice and support.

Glaucoma UK Trustees, Annual Report 2023- 24 13 How did we do? Understanding the risk The progress we made during the year The impact on people with living with. or at risk of, glaucoma Our National Eye Health Week Campaign in September delivered essential bite- sized information via seven short videos, designed to be easily shared on social media. Over l.I million people reached on social media and an estimated 1.5 million readers via an article in The Guardian newspaper. In November, we shared our Road Safety Week message via social media and adverts on petrol nozzles in cities with a lower uptake of eye tests. A range of eye sector publications also featured the campaign. Our social media posts were seen 14,297 times and an estimated 432,000 people saw the petrol nozzle ads. For Father's Day in June, we ran a digital billboard campaign to highlight the hereditary nature of glaucoma, alongside a social media advertising campaign. The billboards were seen by an estimated 39 million people across the UK, with a further 242,219 people reached via social media. During Glaucoma Awareness Week in June, we invited people to share their family stories to help raise awareness of glaucoma in families, encourage people to talk about their eye health history and highlight the importance of regular eye tests. The campaign secured over 21 hours of airtime across a wide network of radio stations and reached 321,742 social media users. An epic challenge by one of our members to run from Land's End to John o, Groats in June thisyear helped to raise awareness of glaucoma across the UK. Over 27 million people reached via regional and national press coverage and 438 items of radio coverage secured.

14 Strategic report Reaching those at highest risk The progress we made during the year The impact on people with living with, or at risk of? glaucoma Our Ramadan Campaign, in partnership with the British Islamic Medical Association and the Muslim Council of Britain. was featured in print media, on the regional news network and on posters in opticians, practices throughout the UK. Individuals received our message via the British Muslim Magazine (45,000 readers) and the magazine's website (74,000 monthly views). Via 27 talks to community groups and other charities across the UK, we helped to raise awareness of glaucoma amongst groups at highest risk. Sessions attended by 460 individuals from varied backgrounds and ethnicities. We ran targeted social media advertising campaigns throughout the year for communities known to be at a greater risk of glaucoma. These included people of African-caribbean and East Asian ethnicity, the over 60s and those experiencing social deprivation. A total of 1,097 searches for free NHS eye tests were made on our website by those who viewed the advertisements. '.1 Glaucoma Awareness ?//iii Week 2024 Make eye drops a part of your Ramadan routine: Wake, drops. Your family ties can protect your eyes Using eye drop5 doe5 not breakyour fast, accordingto the majority of Islamic scholars." Imam 66 66..

Glaucoma UK Trustees, Annual Report 2023 - 24 15 Raising awareness of Glaucoma UK among health care professionals The progress we made during the year The impact on people with living with, or at risk of. glaucoma Glaucoma UK was invited to present at the Glaucoma Risk Prediction event at City University in November 2023 and the Moorfields International Glaucoma Symposium (MIGS) in January 2024. Patient-focused advocacy with over 300 glaucoma professionals. Our Training and Engagement Officers delivered 15 presentations to professionals during the year to raise awareness of the charity, detail the services we provide and encourage patient referrals. Over 200 professionals in attendance from social care, occupational therapy, sensory support, vision rehabilitation, optometry and pharmacy. tACI. However you set your reminders, don't forget your eye health. To,I,iy Get unifvm Yoody PaFk lu￿h￿ BDok éyo t¢sts hr the family. Eyote5tsartntIts5tatr￿Ur￿o￿￿ep1l￿￿caTr5Èe.0r wheTher Jou ntcdgla55CS. Duri￿ kneyo t￿¢￿ an optornetrist*solooksat theheatthofyoureye5. ¥T threatQnj￿dTrSta5e£ SLrha5gl￿c0mI which maybe syffjptomlos5.can b￿der￿Ctedd￿rIweYÈt￿$. Soivs imPtrT¢antt08￿)￿UrtyU lestedie8ularly. What's on your to-do list? Book your eye test today. Vktt ourwebslte tofind out Ifyw are di8ible for a flee tyeiest. Glaucoma UK

16 Strategic report Priority 2: Providing support Supporting people with glaucoma and their loved ones is a vital element of our work. Glaucoma treatment can be complex and challenging? With some individuals finding the treatment worse than the early effects of the disease itself. Understanding glaucoma and its allied conditions and making choices about the many different treatment options can be overwhelming. With clinic appointments generally infrequent and brief, it is hard for individuals to have the time and space they need to ask questions and fully digest the replies. At Glaucoma UK, we want to empower people by offering the right help and advice, delivered in the right way, at the right time. We want to be at the heart of a vibrant, supportive glaucoma community, where people can share their experiences with others facing the same challenges and choices. Our various services provided just under 1 million instances of support, information and guidance during the year. Desired outcomes of our support services include: More people understand their condition and feel able to adhere to their treatment regime. More people at increased risk of sight loss are able to access support from Glaucoma UK when and how they need it. People feel more confident and positive about their condition by being part of a supportive glaucoma community.

Glaucoma UK Trustees, Annual Report 2023 - 24 17 How did we do? Improving understanding and adherence The progress we made during the year The impact on people with living with, or at risk ofi glaucoma Our interattive Digital Glaucoma Support Groups, featuring expert guest speakers, covered topics including'what do you want to know about glaucoma?) Witamin B3 research., 'Preserflo and trabeculectomy,, 'Glaucoma and cataracts Glaucoma jargon busting,, 'All about glaucoma','Eye drops,, and 'Dry eye,. Over 800 people joined the live sessions, with a further 25,199 accessing the recordings on demand. 99% of survey respondents said they would recommend the sessions and 72% gained a better understanding of the disease. PIF TICK accreditation was achieved during the year, confirming the charit￿5 status as a trusted information creator. The PIF TICK is the UK'S only assessed quality mark for health information. PIF TICK accreditation helped to ensure that the information we provided was evidence-based, understandable, jargon- free and up to date. In August 2023 we launched a new, more accessible, version of our popular booklet'Driving and glaucoma,, with updated information covering all four nations of the UK. Over 9,500 copies of the new booklet have since been distributed to individuals and healthcare settings.

18 Strategic report Supporting those at highest risk The progress we made during the year The impact on people with living with. or at risk of? glaucoma The recruitment of an additional helpline advisor increased our capacity to respond to calls and emails. Once again, the most popular topics were eye drops, driving with glaucoma, advice about surgery and support with appointments. A total of 3,544 calls and emails were answered, representing over 560 hours of support. This was a 30% increase on the previous year and our highest annual total to date. Our Healthunlocked forum continued to be a popular resource for those who prefer to take part in online discussions at a time convenient to them. Over 4,000 posts and responses were shared, and 759 new members were welcomed to the community. y hosting 26 face-to-face support groups, we enabled glaucoma patients to meet others, ask questions of professionals and learn more about the help we provide. A total of 350 individuals received in- person support at our 5UPPOrt groups. 9..41 111b •A' 14P Glaucoma UK 520rnembers • 246posts pli¢ Change in eye drops 114vastsJtnh

Glaucoma UK Trustees, Annual Report 2023 - 24 19 Creating a supportive glaucoma community The progress we made during the year The impact on people with living with. or at risk of, glaucoma Our volunteer Buddy Scheme continued to be a source of invaluable peer-to-peer support for those considering glaucoma surgery. The introduction of virtual Buddy Coffee Mornings provided a welcome opportunity to more regularly thank our Buddies and discuss the successes and challenge5 of this Vltal volunteer role. Over 60 buddy pairings were facilitated during the year and 44 new buddies agreed to join the scheme. bringing our total of buddy volunteers to 82. Case study volunteers shared their experiences of living with glaucoma via radio and TV interviews, podcast recordings, billboard campaigns and media interviews. Case study stories were also featured in every edition of our Insight magazine. Our community of over 90 case study volunteers helped us by sharing stories that were featured in all our major awareness raising campaigns during the year. Growing our Glaucoma UK community has been a key priority for our 50th anniversary. In addition to further improving our member communications, we introduced a new'welcome webinar, in July, featuring key facts and statistics about glaucoma and information about the services we provide. We welcomed 638 new members to our 4,849 strong community of glaucoma patients and professionals. Sign-ups for our'Focus' e-newsletter, grew significantly during 2023-24, driven largely by successful, targeted social media campaigns, helping us reach and engage a broader audience. The Focus audience more than doubled during the year, with a total of 5,398 subscribers by July 2024.

20 Strategic report The progre55 we made during the year The impact on people with living with, or at risk of, glaucoma We ran our first Digital Glaucoma Support Group led by glaucoma patients during the year. The session entitled, 'Lived experience of eye drops,, featured speakers recruited via our online Healthunlocked forum. Over 20 people attended, with 85% stating that their knowledge of glaucoma increased and 99% willing to recommend the session to others. A special-edition membership magazine called 'lnspire' showcased the inspirational fundraising efforts of our members and publicised a new campaign called '1 will... inviting pledges of support for people living with glaucoma. From urging family members to have an eye test, through to running a marathon, responses to our'l Will... campaign highlighted the loyalty and dedication of the Glaucoma UK community. For World Glaucoma Week in March, we ran a series of webinars showcasing glaucoma care in different parts of the world and revealing how research findings are shared across the globe. A total of 30 attendees enjoyed our 'Glaucoma care everywhere, series. The annual Excellence in Glaucoma Care Award, which is presented at our Annual General Meetin& celebrates individuals or teams making remarkable contributions to the field of glaucoma care. The winner for 2023-24 was Zainab Alrikabi, a PhD student at Glasgow Caledonian University, who gave first- class care to participants in her research study.

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22 Strategic report Priority 3: Supporting research and development As the only UK charity solely funding research into glaucoma, our work to support the most promising studies, led by the most talented researchers, is a key aspect of our mission. In addition to our annual awards for ophthalmologists, health and social care professionals and members of the UK and Éire Glaucoma Society (UKEGS), we also offer an 'Open Call, programme to attract novel research into new methods of diagnosis, care and treatment. By helping to fund the Professor of Ophthalmology at University College London and working with partners including the Royal College of Ophthalmologists, we aim to deliver an ambitious research programme that will have a real impact for the people we serve - now and in the future. In 2023-24, we awarded new grants to the value of £412,711 (but with one of £49,489 to be accounted for in next year's accounts. due to a contract delay at the financial year-end). The grants were awarded in open competition by an awards panel chaired by a Glaucoma UK trustee. Other panel members were drawn from our Clinical Advisory Panel and our lay member volunteers. All awards were subject to a peer review process. Desired outcomes of our research programme include: More of our research projects demonstrably transform glaucoma prevention, diagnosis and treatment. Research we fund is more widely disseminated to inform and improve glaucoma care. )> We achieve more leverage from our research support and sector relationships.

Glaucoma UK Trustees, Annual Report 2023 - 24 23 How did we do? Transforming glaucoma prevention, diagnosis and treatment. The progress we made during the year The impact on people with living with, or at risk of. glaucoma We launched the brand-new Pitts- Crick Career Development Research Fellowship in March, in recognition of the charity's 50th anniversary. Through this three-year programme, we hope to support a rising star in glaucoma research who will go on to play a pivotal role in transforming glaucoma care. Promising applications have been received from individuals across a range of specialisms including ophthalmology, optometry and research science. The Fellowship will be awarded in early 2025. The £50,000 UKEGS research grant for 2023 was awarded to Patrick Gunn, Lead Optometrist at the Manchester Royal Eye Hospital, for his project entitled 'Minimising the implementation gap in management of narrow angle glaucoma suspects through education and technology,. The project commenced in December 2023 and will run for two years. By supporting optometrists to manage low-risk patients more effectively in community settings, the project seeks to reduce unnecessary hospital referrals. free up time for more complex cases and reduce treatment delays. We were delighted to award two grants for this year's joint award with the Royal College of Ophthalmologists: Both projects will explore innovative, novel therapies for glaucoma, particularly focussing on the causes of poor drainage of fluid from the eye. Dr Lisa Hill, Associate Professor at the University of Birmingham, was awarded just under £1 00,000 for her project to explore whether a new anti-scarring treatment can be delivered to the eye to improve drainage through the trabecular meshwork. The studies offer real potential for the discovery of an alternative to pressure- lowering eye drops.

24 Strategic report The progress we made during the year The impact on people with living with, or at risk of? glaucoma Dr Victoria McGilligan at Ulster University was also awarded just under £100,000 for her investigation into an antibody which can harness the bOd￿S natural immune system and reduce inflammation in the drainage channels of the eye. (See previous page) The £50.000 Health and Social Care Professionals, grant for 2023 was awarded to Matt Roney at Liverpool Hospital Foundation Trust and the University of Liverpool. The project will investigate whether OCT can be used to identify early signs of surgical failure after surgery. Earlier intervention after surgery could mean more successful surgeries, with fewer complications and - ultimately the reduction of sight loss due to glaucoma in the longer term. Glaucoma UK is now an introductory member of the Association of Medical Research Charities (AMRC). We are reviewing and improving our processes and procedures in order to achieve full membership status within the next two years. By becoming an AMRC member we will benefit from opportunities to connect and collaborate with other research organisations and receive support to fund the best and most impactful research.

Glaucoma UK Trustees, Annual Report 2023 - 24 25 Glaucoma UK Chair of Ophthalmology In partnership with University College London and the Moorfields Biomedical Research Centre, the charity provided continued financial support for the role of the Glaucoma UK Chair of Ophthalmology for Glaucoma and Allied Studies - Professor David (Ted) Garway- Heath. Professor Garway-Heath's achievements for the year included: 9 new scientific publications 18 national and international lectures for a range of organisations including the Irish College of Ophthalmology (Mooney Lecture), European Glaucoma Society, Italian Glaucoma Society, Imaging and Perimetry Society and the Moorfields International Glaucoma Symposium. Provision of strategic input and guidance for the European Glaucoma Society (EGS) as member of the Executive Committee and immediate Past President Furtherance of the EGS patient advocacy project, including the first patient-initiated and organised plenary session at the European Glaucoma Society Congress in Dublin. Chief Investigator for the research projects: 'The association between mitochondrial function and glaucoma-identifying susceptible patients 'Identifying the genetic basis for heritable normal tension glaucoma, with a focus on mitochondrial function, and, 'NicotinAMide in Glaucoma (NAMinG): A randomised, placebo-controlled, multi-centre, Pha5e111 trial, to test the effectiveness of vitamin B3 as a treatment for glaucoma.

26 Strategic report Disseminating research findings to inform glaucoma care The progress we made during the year The impact on people with living with, or at risk of) glaucoma Research jointly funded by Glaucoma UK and the UK & Eire Glaucoma Society (UKEGS) was published in the prestigious Nature Medicine magazine in June 2024. Nature Medicine has one of the highest impact factors of any journal (the measure of how frequently the articles have been cited in a particularyear). The research findings will help to identify patients at risk of faster progression, informing personalised treatment strategies and targeted therapies. The projett, which identified a new biomarker for glaucoma progression, was carried out by Bledi Petriti and Professor Garway-Heath, the Glaucoma UK Professor of Ophthalmology. Following publication of the article, Ted Garway-Heath was also interviewed on BBC Radio 4's'ln Touch, programme. Other projects we have funded have resulted in presentations at conferences such as the world-leading ARVO (the Association for Research and Vision in Ophthalmology) and UKEGS, as well as publications in journals including Cells and PLOS One. Ensuring that the outcomes of our research funding are widely shared among glaucoma professionals will help improve the prospects for prevention and cure. A new UK Clinical Eye Research Strategy, featuring consultation feedback from Glaucoma UK members, was featured on BBC Radio 4's In Touch programme in July. The strategj sets out new priorities for all aspects of eye research, but glaucoma was the topic receiving the highest consultation response. The strategy will help channel precious resource in eye research towards the most important topics. It will encourage government, charity and industry funding into these areas.

Glaucoma UK Trustees, Annual Report 2023 - 24 27 Achieving leverage from our research and sight sector relationships The progress we made during the year The impart on people with living with. or at risk ofi glaucoma Glaucoma UK continued to be an active member of the Vision Impairment Charity Sector Partnership (VICSP), which was rebranded as the Wision Partnership, during the year. This partnership of eight organisations, including RNIB and Guide Dogs UK, seeks to achieve alignment and added value for people living with - or at risk of sight loss. Involvement in the partnership offers the combined resources and collective influence of all key organisations in the sight sector. Priorities for the next three years include: Inf luencing national policy. Improving access to services for underserved communities. Advocating for more medical research funding. A new strategic direction was set out for the group in January, aligning closely with Glaucoma UK'S Theory of Change. Glaucoma UK'S Head of Research led a workshop for charity partners in June, exploring ways to increase research funding and get more patients involved in ground-breaking eye research. Over 20 representatives from eight sight sector organisations shared ideas and identified joint working opportunities. We became an affiliate charity of 'Our Future Health, during the year- a charitable health research project seeking 5 million volunteers to share their health data and thereby help develop new ways to prevent, detect and treat diseases. Involvement in the project will enable us to learn from their expertise in reaching high-risk populations and securing engagement in health research.

28 Strategic report The progress we made during the year The impact on people with living with, or at risk of. glaucoma Glaucoma UK is taking part in a thought-leadership project, led by the pharmaceutical company Santen. to expSore future trend5 in glaucoma diagnosis, treatment and management. Following research with glaucoma patients and professionals, a series of studies will be produced, focusing on artificial intelligence, genomics and biomarkers, service delivery, innovative treatments, health equity and patient education. With an overarching theme of 'the glaucoma patient of the future,, Glaucoma UK will be well placed to ensure that the interests of its beneficiaries are at the heart of this important piece of work. In January, Glaucoma UK announced a one-year partnership with the care plan provider OcuPlan to improve awareness of eyecare options for glaucoma patients. The collaboration is a joint effort to enhance awareness and support for individuals living with the disease. Just under 100 people attended a Digital Glaucoma Support Group led by OcuPlan's CEO, and 14 Glaucoma UK members took part in a consultation to help OcuPlan understand the challenges faced by glaucoma patients. In support of the partnership, OcuPlan contributed £50,000 towards the delivery of Glaucoma UK'S free support services. As well as working together to improve understanding of glaucoma more generally, the partnership will also promote patient choice and informed decision-making about eyecare options. TOZ

Glaucoma UK Trustees, Annual Report 2023 - 24 29 The progress we made during the year The impart on people with living with. or at risk of> glaucoma Our relationship with Specsavers continues to offer a valuable opportunity to showcase the work of Glaucoma UK and amplify our messaging. All joint awareness raising in partnership with the UK'S biggest high street optometry chain offered a valuable opportunity to highlight Glaucoma UK'S key messages and showcase the ways in which those working in community optometry can help deliver our charitable objectives. Chairman Anthony King was a guest speaker at the Specsavers, Professional Advancement Conference in September 2023 and also the IO0% Optical event in London's Excel in February 2024. Joint messaging was agreed for World Glaucoma Week and Glaucoma Awareness Week. For the latter, Specsavers worked with artist Louisa Schmolke to create a piece of art that reflected the effects of glaucoma on eyesight. The artwork was kindly gifted to Glaucoma UK. •1

30 Strategic report Priority 4: Influencing policy and professional practice With the eyecare landscape changing at such a rapid pace. we must ensure that the voice of people living with glaucoma is heard by policy makers and those making decisions about care services. We also feel we have an important role to play in providing information, advice and support to health care professionals. We want all those involved in delivering glaucoma care to have up-to-date information and access to effective professional network5 for sharing best practice. Through the work of our Professional Engagement Team, we seek to make connection5 that can help to promote, protect and safeguard the interests of people living with - or at risk of - glaucoma. Through our administration and support for the United Kingdom and Éire Glaucoma Society (UKEGS) - which became part of Glaucoma UK in 2019 - we play a key role in bringing together scientists and clinicians in a vibrant, aspirational scientific community. Desired outcomes of our professional engagement work include: More people at increased risk of glaucoma have equitable access to eyecare services. Those making decisions on policy and commissioning take greater account of glaucoma patient perspectives. More people at increased risk receive timely access to eyecare services. More professionals feel better informed and equipped to support people to live well with glaucoma.

Glaucoma UK Trustees, Annual Report 2023 - 24 31 How did we do? Promoting equitable and timely access to eyecare services The progress we made during the year The impact on people with living with, or at risk of? glaucoma A Westminster Hall debate took place in April, focusing on the current state of glaucoma care. Glaucoma UK was referenced by the shadow minister for health, along with our message about the importance of regular eye tests. Subsequent requests for media comment allowed us to highlight the benefits of a National Strategy for Eye Care to ensure equality for glaucoma patients across the UK. In April, Glaucoma UK was represented at an All-Party Parliamentary Group (APPG) open meeting about innovation in Eye Health. Discussion topics included Al assisted diagnostic hubs and community monitoring. Glaucoma UK supported the call for better connectivity between primary and secondary eyecare and the need for more consistency in provision across the UK.

32 Strategic report Sharing glaucoma patient perspectives The progress we made during the year The impact on people with living with, or at risk of, glaucoma Glaucoma UK represented glaucoma patients at a number of eyecare settor forums during the year, including The Clinical Council for Eye Health Commissioning (CCEHC), The Ophthalmology National Steering Group and The UK Ophthalmology Alliance (UKOA). As members of the CCEHC, we supported the development of a Clinical Specification for Community Minor and Urgent Eye Care Services. We also shared patient insights with the National Clinical Direttor as she works on a plan to improve eyecare across the UK. Through the National Steering Group, we recommended suggested glaucoma research priorities to the National Institute of Health Research (NIHR). The charity was also represented at a National Institute for Health and Care Excellence (NICE) committee meeting regarding approval of the new pressure- reducing eye drop, Roclanda. Following the NICE committee meetin& which featured a submission from a Glaucoma UK patient member, the drug Roclanda was approved. Glaucoma UK attended two stakeholder meetings with the DVLA during the year, to represent the views and experiences of drivers with glaucoma. Glaucoma UK staff and members took part in a consultation to help develop a new Eye Care Support Pathway to help transform eyecare services. With far greater emphasis on patient experience, the pathway focuses on the practical and emotional support that individuals need at various stages of their treatment. Building upon the launch of the pathway, we are now working with sector partners to develop a glaucoma-specific strand, that will better reflect the particular needs and challenges faced by those living with glaucoma. Glaucoma UK was delighted to take part in a nation-wide campaign by charities, passenger watchdogs and disability groups to speak out against the proposed mass closures of ticket offices during the year. Proposals to close ticket offices were withdrawn by train operators in November 2023.

Glaucoma UK Trustees, Annual Report 2023- 24 33 Ensuring professionals are informed and well equipped to support glaucoma patients The progress we made during the year The impact on people with living with, or at risk of, glaucoma The 2023 UKEGS Conference in London was the biggest in the event's history, with over 500 delegates. The conference brought together top glaucoma experts, researchers, and professionals for a two- day programme to explore the theme of 'Best Evidence for Best Practice" The programme included a presentation from the Glaucoma UK CEO, highlighting the anxiety felt by those receiving a glaucoma diagnosis and current shortfalls in patient communication. We were delighted that the General Optical Council approved our Eye Drop Support training for their CPD scheme during the year, allowing optometrists and dispensing optician5 to claim career development points. Course attendees receive Eye Drop Support Boxes containing information on eye drop usage and samples of the aids available to help patients put them in. Over 200 boxes have been distributed across the UK since the scheme was launched in 2022. IO0% of course attendees found the dispensing aids useful and 93°A found it helpful learn more about the barriers people face in using eye drops. 95% stated that the course taught them something new about glaucoma. Our team of Training and Engagement Officers delivered a new pilot project for pharmacy and optical practice front of house staff, to help them better support people with their eye drops. We welcomed 61 attendees to 8 training sessions, with IO0% of survey respondents agreeing they would recommend the course.

34 Fundraising review Fundraising review Nearly three-quarters of our total income was made up of voluntary gifts from our generous members and supporters. This demonstrates the critical role our glaucoma community plays in funding our work and we are deeply grateful to each individual, family? companyy trust and foundation that supported us throughout the year. Collectively? our donors helped us to raise just under £1.8 million in support of our efforts to make a difference to people living with glaucoma. Legacy gifts Legacy gifts are essential for us, and we are indebted to the members, supporters, and grateful patients who remember Glaucoma UK in their wills each year. In 2023- 24, we recorded a total of £1,528,917 in legacy income and received 32 new legacy notifications. These gifts are vital not only for sustaining our current work but also for enabling us to plan confidently for the future. Legacy donations are a testament to the positive impact we have had on individuals, lives, and we are grateful to those who have chosen to support us in such a meaningful way. We are also grateful to their families and friends, many of whom choose to stay in touch and continue their loved one's support for our work. Legacy gifts ensure that we can continue our mission to prevent sight loss from glaucoma for future generations and allow us to dedicate more funding to essential glaucoma research. We have, however, seen a decline in the number of new legacy notifications in recent years. With an average 12-month lag time between notification and receipt of the funds, this threatens to have a significant impact on our voluntary income in the medium-term. It is essential, therefore, that we continue to communicate the enormous importance of legacy gifts to our supporters and that we work ever harder to ensure membership of our charity proves to be an invaluable resource for those who need us during their lifetime. Other income To help ensure a sustainable future for the charity, we have been focusing on diversifying our income to reduce the current strong emphasis on legacy gifts. In 2023-24, we were delighted to receive support from our community via a range of income streams, including membership subscriptions, one-off gifts, responses to

Glaucoma UK Trustees, Annual Report 2023 - 24 35 appeals, regular giving, Christmas card sales, In Memoriam donations, corporate partnerships, challenge events, and our weekly lottery. Together, these contributions totalled £363,929, a 34% increase from the previous year (2023: £270,677). We are always especially touched to receive In Memoriam donations from those who choose to honour their loved ones by directing funeral collections to Glaucoma UK. Income from this source showed a 250A increase year-on-year (2024: £21,185 versus 2023: £16,821). N￿Gr Our corporate supporters also played a vital role, contributing £84,194 to our income- over five times higher than the previous year (2022-23: £14,649). This increase was largely thanks to our partnership with Ocuplan, who contributed £50,000 towards our community outreach work. We were also grateful to receive £20,000 from our licencing agreement with Specsavers, which steered our joint promotional efforts throughout the year. In addition, for Glaucoma Awareness Week 2024, Specsavers donated a piece of art that had been specially commissioned to show the effects of glaucoma on eyesight. The artwork will be used to help raise awareness of glaucoma and generate funds through auction or Sale. 1974.2Q4 Challenge event fundraising We are thankful for the extraordinary efforts of our challenge fundraisers, whose mental and physical determination raised an impressive run to prevent glaucoma Sight Ios5.-

36 Fundraising review £80,022 for Glaucoma UK in the past financial year- exceeding our previous highest-ever year in 2022-23. It was especially heartening to see how the number of challenge fundraisers has increased from only three participants a few years ago to 18 people in 2023- 24, highlighting the growing strength and commitment of our glaucoma community. Once again, Professor Keith Barton, Consultant Ophthalmic Surgeon at Moorfields Eye Hospital and former Chair of Glaucoma UK, undertook the gruelling London to Paris bike ride in aid of Glaucoma UK. Crossing the finishing line in under 24 hours, his achievement raised £30,329, This brings Keith's remarkable fundraising total to over £168,000 for Glaucoma UK in the last 11 years. We were particularly grateful to Martin Higgins, a distinguished former member of the RAF Red Arrows, who took on a monumental challenge to run from Land's End to John o, Groats to raise awareness of glaucoma as part of our 50th anniversary celebrations. Martin's efforts raised a total of £18,625 - representing almost half of the £38.970 raised from our members and supporters toward5 the charity's new Pitts-crick Research Fellowship. A special thanks also goes to James Broadbent, who took on the challenge of cycling a distance equivalent to the height of Everest-nearly 8,850 metres-raising £3,830 in the process. We are equally grateful to Connor Bice, who cycled an impressive 150 miles - the equivalent distance from his family home to Birmingham Children's Hospital and back - to raise awareness of primary congenital glaucoma following his daughter's diagnosis at just seven months old. Connor's incredible effort raised £3,025. Our thank5, also, to Tanika, Sally, Richard, Beth, Francesco, Grace, Katy and Kathryn who took part in various marathons, runs and walks across the UK to raise funds in support of our essential work. Over 30 years Since he last attempted the feat in aid of Glaucoma UK, former Chair and Consultant Ophthalmologist, Michael Miller ran the London Marathon in April. Thanks to his incredible efforts, Michael raised £21,238 for the charity.

37 •• 41 r !ffiAi,ji.[, fr ITY.-

38 Fundraising review Organisations who helped us We would like to take this opportunity to thank the following organisations for their support during the year: ELIOS Vision Envision Pharma Group Glaukos Specsavers Stranraer Folk Club The Dandy Charitable Trust The Emily Weircroft Charitable Trust The Masonic Lodge of Equity No. 3692 The Monk Bretton Charitable Trust The Wyndham Charitable Trust Thea Pharma UK Wyseliot Rose Charitable Trust Harry and Gertrude Landy Charitable Trust I-STAR Medical KMS (UK) LTD Medicom Healthcare Ocuplan Pinner Folk and Blues Club Santen UK 14 ) GlaucorTra SO￿ars Iljll.. r/ij Ilk 2,

Glaucoma UK Trustees, Annual Report 2023 - 24 39 Fundraising controls Securing and maintaining the trust of our donors and the public is vital to the success of our fundraising activity. We therefore have controls in place to ensure our fundraising is transparent, ethical and compliant with current regulations. We have the benefit of a designated Fundraising Trustee Advocate on our Board of Trustees, to ensure oversight at the highest level. In addition, our Finance and Governance Committee monitors fundraising performance, control and regulation through quarterly reviews. Glaucoma UK is registered with the Fundraising Regulator and follows the Code of Fundraising Practice. We comply with the key principles embodied in the Code and are committed to the Fundraising Promise. Our website carries our complaints policy for the public and explains clearly how an individual may complain. We received no complaints from August 2023 - July 2024. We are also registered with the Fundraising Preference Service 50 that individua15 can opt out from receiving fundraising communications, should they wish. We received no such requests during the year. To ensure that all reasonable step5 are taken to protect vulnerable adults, Glaucoma UK complies with the Institute of Fundraising guidance relating to the needs of people in vulnerable circumstances and our activities are governed by an Ethical Fundraising Policy and Supporter Promise. Glaucoma UK monitors any third parties working with us to help raise funds, ensuring that they adhere to the Code of Fundraising Practice and are operating to the highest possible standards of respect for the personal data and wishes of our supporters and prospective supporters. We worked with one third party - Bequeathed Limited - in the delivery of a free wills service, but did not work with any external professional fundraising agencies during the year. Our Lottery activities are managed under our Gambling Commission licence which ensures we can meet our legal obligations and provide the necessary protections for our players.

40 Looking forward Looking forward With 50 years of history to build upon, we now have an exciting opportunity to set out ambitious and inspiring plans for the future. Our ultimate goal is to ensure that the charity doesn't exist to celebrate its IOOth anniversary. By f inding that all-elusive cure for glaucoma, we can eliminate the need for our services. It's a tall order, but one that merely serves to sharpen our focus and determination. In pursuit of this goal, we will be working towards a number of exciting outcomes in 2024-25: Expanding our reach and impact Our programme to maximise our impact across the UK will continue in the coming year, with investment in new colleagues to help grow and develop our fundraisin& outreach, helpline and digital communications activities. Engaging new audiences Our team of training and engagement officers will be developing a series of pilot projects to engage those at highest risk of glaucoma sight loss in targeted communities across the four nations. Thi5 will help to identify exactly what effective community engagement for underserved audiences looks like and will enable us to collect valuable impact data to help seek funding to roll out this work across the UK in due course. Representing the patient voice We have welcomed lots of new members to the charity as a result of our anniversary year celebrations and so this is the perfect time to collect more comprehensive and up-to-date information on glaucoma patient perspectives. We will be collecting feedback from our members on a wide range of topics across the coming year in order to more accurately and effectively represent their views and concerns to those who develop policy, provide treatment and make decisions about glaucoma care.

Glaucoma UK Trustees, Annual Report 2023 - 24 41 Growing our support for research The appointment of a Head of Research in early 2024 is already paying significant dividends for our work in this area and we will be further expanding our research funding in the coming year. In addition to the introduction of the charity's first- ever Career Development Research Fellowship, we will be offering a second PhD studentship and working with other sight sector charities to explore options for transformational partnership projects. Having the benefit of our £3.87 million Designated Research Fund offers an exciting opportunity to invest in more ambitious, larger scale projects that have the potential to transform current approaches to the diagnosis, treatment and monitoring of glaucoma. Improving efficiency We will be exploring the potential offered by artificial intelligence to assist our work in the coming year and will be increasing the use of automation within Glaucoma UK'S administrative systems. This will free up the time available for engaging with audiences and developing new products and services for people living with glaucoma. Enhancing quality standards Following on from our achievement of PIF Tick accreditation for our health information, we will be signing up to the Helplines Partnership Quality Standard in 2024-25 to further improve the service we offer for those reaching out to us for help and advice. Did you know? 2 in 25 African Caribbean people have glaucoma 7,Ji I Glaucoma UK

42 Financial review Financial review Against the backdrop of a mixed, but gradually improving economic environment, Glaucoma UK ended the Financial Year 2023-24 with a net increase in funds of £720,213. This takes the charity'5 total funds to £8,767,960 (2023: £8,047,747). Net income showed a surplus of £280,305, largely due to the receipt of an unusually large legacy during the year. Expenditure increased to £2,077,745, up 18.5% on the previous year, in line with the strategic objective to maximise Glaucoma UK'S reach and expand services in the coming three-to-five year period. With recession avoided after the inflationary pressures of the previous year, movements in the stock market resulted in unrealised gains of £439,908 on our investment portfolio. Incoming resources At £2,358,050, total income was up 33% on the previous year (2023: £1,773,879). This was thanks to an exceptional legacy (the largest in the charity's history) which resulted in a growth in voluntary income of £303,273 year-on-year (2024: £1,787,919 versus 2023. £1,484,646) Legacies remain a crucial revenue stream for Glaucoma UK, representing just under 70% of total income, on average, over the last five years. As in the previous year, we continued to receive more complicated bequests, often resulting in an extension in the time between being notified of a gift and receiving the funds. This is reflected in the legacy debtor figure, which remains high at £1,619,363. In recent years, we have invested in additional staff resource and worked to further improve our administrative systems in an ongoing drive to reduce that figure. Income from our charitable activities was up by £245,161 on the previous year (2024: £370,197 versus 2023: £125,036). This was due in part to higher sponsorship and delegate income for our UK and Eire Glaucoma Society (UKEGS) Conference and also the receipt of £81,950 in relation to corporate support, including our partnership agreements with Specsavers (£20,000) and

Glaucoma UK Trustees, Annual Report 2023 - 24 43 OcuPlan (£50,000). In addition to the benefits these partnerships bring in helping to amplify our key messages and supporting the delivery of our Strategic objectives, this is an increasingly important income stream for the charity as we seek to reduce the emphasis on legacy gifts. Work to develop this area will continue throughout the strategic plan period, but with due regard to the importance of independence and objectivity in the charity's activities and decision-making. address growing demand in both the number and nature of helpline calls, we also invested in a third helpline advisor. Total staff numbers at the year- end were 22.88 (full-time equivalent) compared to 18.53 at the end of 2023. Other areas of expenditure growth included the costs of a larger, more expensive London-based UKEGS conference and more expenditure on patient education, including our ongoing work to update and reprint our suite of information booklets. We benefitted from the Google Ads grant scheme during the year, with free advertising to the value of $64,861 (£50.449 as at 31 July 2024). Google Ads enabled us to Serve advertisements to people searching online for particular keywords and encourage traffic to the charity's website. We accounted for £363,222 in respect of new research grants awarded during the year. Thi5 was down by £45,438 on the previous year (2023: £408,660), due to a third-party contract delay that remained unresolved at the financial year end. Taking account of the £49,489 delayed award, we actually granted £412,711 in funding for new projects, which was the highest figure to date and maintains our strategic drive to increase the impact of our research support. In a move to address timing issues at the financial year end, we will be redesigning our grant awards programme in 2024-25. Total expenditure on research, including staff costs, premise5. administration and professional fees was £431.080 during the year. Resources expended Total expenditure in the year was £2,077,745, up by £324,521 on the previous year (2023: £1,753,224). As we continue to build capacity within our team and expand our activities to more effectively deliver our Theory of Change, staff costs accounted for 43Yo of this increase, rising to £975,235 from £835,770 in 2023. During the year, we introduced the role of Head of Research, the charity's first ever designated resource in this important strategic area. To help Restricted Funds Of total funds at the year end, the sum of £1,629,943 was restricted. The

44 Financial review majority (£1,504,578) represents the Chair Fund, which will support the Chair of Ophthalmology for Glaucoma and Allied Studies until his term comes to an end in March 2028. Of the remainder, £75,223 15 restricted to the delivery of the UK and Éire Glaucoma Society (UKEGS) conference, and the rest is allocated to a range of specific small projects at the request of the donors. General funds totalled £2,797,225 (2023: £2,140,977) against a cash reserves requirement of £2,005,807 at the year- end. The surplus will support the delivery of the new Theory of Change framework and the expansion of our services in the period 2023-2026. Other unrestricted funds at the year- end amounted to £4,340,791 (2023: £4,387,968). Of the total, £3,878,078 is designated to the funding of research, including a contribution to the new Pitts-crick Research Fellowship, the recruitment of a new PhD Studentship in 2025 and new partnership initiatives currently in development with other research charities in the sight sector. A further £434,745 remains designated for equipment replacement and infrastructure development, which will include modernisation of the Head Office environment (scheduled for 2025) and the subsidy of two new posts to strengthen our staffing infrastructure as we work to grow additional income. We introduced a new restricted fund during the year - the 50th Anniversary Fund - for donations towards our new Pitts-crick Research Fellowship. Reserves policy The policy of the trustees is to maintain at least the minimum of cash reserves and working capital sufficient to meet known development plans, as well as the day-to-day needs of the charity. Funds are also held in reserve to provide secure, sustainable support for our beneficiaries and to ensure we can commit to ambitious, long-term plan5 to help bring an end to sight loss from glaucoma. Going concern In assessing the charity's Status as a going concerri, the trustees have considered a range of information in relation to the financial year ahead, including the current Status of the UK economy, the charity's cash resources and known liabilities. The Trustees recognise the risk to income posed by the reliance on legacy gifts and factors outside the organisation's control, such as economic uncertainty and investment volatility. Having considered these factors, the Board of Trustees agreed to maintain cash reserves of 12 month5, operating costs during the year. The charity's three-year financial plan for the period 2024- 2027 shows the charity to have adequate resources to continue operating an effective service

Glaucoma UK Trustees, Annual Report 2023 - 24 45 for at least 36 months and to meet its obligations as they fall due. The financial statements have therefore been prepared on a going concern basis. The total value of our investment portfolio at the year-end was £7,481,616, an increase of £621,627 on the previous year (2023: £6,859,989). A total of £198,496 in dividends was reinvested into the portfolio and no funds were drawn down during the year. The fund benefited from unrealised gains totalling £439,908. Investment policy and performance The charity's assets are invested in the Rathbone Core Investment Fund for Charities, with management delegated to Rathbone Investment Management Ltd. A total return approach is adopted for the portfolio and withdrawals can be comprised of physical income andlor capital gain. The investment portfolio underperformed against the composite index benchmark by 2% during the year but outperformed its peer group. In reviewing the Investment Policy for 2024-25, the trustees were mindful that the aim of the portfolio is to maximise total return subject to a medium level of risk over the long term. The decision to maintain the risk profile and retain the fund at its current level was taken after consideration of steady economic groK¢h in the UK and Eurozone, continued reduction in inflation and the reasonable health of the US economy. Our Investment Policy is: To maximise total return subjett to a medium level of risk. To ensure that the charity's assets are invested widely and diversified by asset class and by security. To avoid direct investment in any companies manufacturing tobacco or tobacco products. To avoid investment in any companies that derive more than 10% of their revenues from the manufacture of alcoholic beverages, armaments, gamblin& high interest rate lending or pornography. Responsibility for monitoring the performance of the investment portfolio is delegated to the Finance and Governance Committee and performance benchmarks are reviewed with the fund managers on an annual basis.

46 Trustees, advisors and staff Trustees, advisors and staff The trustees (who are also direttors under company law) are: Professor Anthony King Chair Mr Stephen Epstein Vice Chair (Chair, Finance & Governance Committee) Hon Treasurer (Finance & Governance Committee) Chair. Clinical Advisory Panel Mr Prabhakar Sundaresan Miss Winifred Nolan Dr Susan Blakeney (Finance & Governance Committee) Ms Teresa Borsuk (Finance & Governance Committee) Dr Roxanne Crosby-Nwaobi Mr Julian Exeter (Retired, 14 March 2024) Professor Cecilia Fenerty Mrs Yolanda Laybourne Fundraising Advocate (Finance & Governance Committee) Professor Roshini Sanders Mr Raymond Spendiff (Finance & Governance Committee) Mr Christopher Hunton Chair Fund Advocate (Since 14 March 2024- previously co-opted)

Glaucoma UK Trustees, Annual Report 2023- 24 47 Chief Executive & Company Secretary Joanne Creighton Company Number 1293286 Charity Number 274681 OSCR Number SC041550 Registered office & operational address Woodcote House, 15 Highpoint Business Village, Henwood, Asford, Kent, TN24 8DH www.glaucoma.uk Bankers Barclays Bank plc, I Churchill Place, London, E14 5HP CAF Bank Ltd, 25 Kings Hill Avenue, Kings Hill, Kent, ME19 4JQ HSBC Bank plc, Camberwell Green, 23 Denmark Hill, London, SE5 8RP Auditors Xeinadin Audit Limited, 12 Conqueror Court, Sittingbourne MEIO 5BH Investment Managers Rathbones Investment Management Ltd, 30 Gresham Street, London EC2V 7QN

48 Structure and management Structure and management Glaucoma UK is the operating name of the International Glaucoma Association Ltd, which was incorporated on 15 July 1976 and registered as a charity on 20 December 1977. As Glaucoma UK is both a charity and a company limited by guarantee, all board members are directors for the purposes of company law and trustees for the purposes of charity law. The objects of the charity are def ined by its Articles of Association (last updated in 2024), which also set out trustees, powers and the permitted activities of the charity. As we entered our 50th anniversary year, there was a useful and welcome opportunity to review and refresh the Articles of Association to ensure our governing document remains fit for purpose into the next half-century. Changes included: Simpler language to improve readability and transparency. Updated terminology, e.g. 'Charity' not 'Foundation'. Removal of obsolete clauses. Updated Objects to include a specific reference to providing advice and support, which is now such a vital aspect of our work. Modernisation of our activities, e.g. communication via electronic means and the holding of virtual meetings if required. Clarification of the Board'5 powers, e.g. explicit reference to employing staff and procuring consultancy advice as necessary. Increased flexibilityi most notably the ability to award a research grant to a project led by a serving trustee, subject to the appropriate conflict of interest controls. Improved clarity around the role and powers of our members to help as we seek to recruit more members and encourage more people to exercise their right to vote. The membership approved the revised Articles of Association at the AGM on 14 March 2024.

Glaucoma UK Trustees, Annual Report 2023 - 24 49 The Board and committees matters. The chair of the CAP oversees the award of research grants. The Board comprises not fewer than 8 and no more than 15 persons elected by the Members (or appointed by the Board to fill a temporary vacancy). and not more than three persons co-opted by the Board. Trustee recruitment and training When seeking new Board members, trustees have regard to any existing skills or knowledge gaps or any new disciplines that would be helpful in delivering the charity's future plans. Due consideration is also given to diversity and the need to ensure that the Board appropriately represents the communities served by the charity. New trustees are sought using existing networks, advertising or professional recruitment agencies, as required. Candidates are interviewed by a sub- committee of trustees, followed by a meeting with the Chair. Suitable individuals are invited to meet the remaining trustees at a Board meeting and are then put forward to the membership as the Board's preferred candidates at the Annual General Meeting. Voting members are also eligible to nominate themselves or other5 for election. The current Board comprises people living with glaucoma, those with close family connections with the condition and others with backgrounds in ophthalmology, nursin& optometry¥ finance, public relations and business. At least three trustee positions are held each year by Fellows of The Royal College of Ophthalmologists or medically qualified equivalents. Trustees retire after serving a three- year term but are eligible for re-election to a maximum of nine years, Service. Those serving prior to the 2023 AGM are entitled to serve for a maximum of 12 years. Board meetings take place four times a year on either a face-to- face, virtual or hybrid basis. There is one sub-committee: the Finance and Governance Committee, which has delegated responsibility to oversee finance, investments, risk management and policy. Consisting of six trustees, the committee meets quarterly in advance of each Board meeting and on an ad-hoc basis, should the need arise. A Trustee Handbook sets out trustee roles and responsibilities. A personalised induction is provided for all new trustees, including a charity overview and briefings on finance, fundraisin& support services and communication. Direction is also provided on the Charity Commi55ion Guidance, 'The Essential Trustee, and The charity also has a Clinical Advisory Panel (CAP) to advise on clinical

50 Structure and management trustees are required to undertake 'Understanding Governance, training within six months of joining the Board. Ongoing training is provided as required, including attendance on external courses or participation in internal workshops and briefings. Related parties and connected charities Glaucoma UK acted as an agent for the unincorporated organisation the United Kingdom Paediatric Glaucoma Society (UKPGS) during the year, providing infrastructure and administrative support. UKPGS exists to promote the exchange of knowledge between glaucoma specialists, stimulate research, establish a scientific community and promote interest in glaucoma as an ophthalmological sub- specialty. One trustee of Glaucoma UK also sits on the trustee board of UKPGS. Operating responsibility Day-to-day responsibility for delivering services and achieving strategic and financial aims within organisational policies and the law 15 delegated to the Chief Executive, supported by the Senior Management Team. In 2022 Glaucoma UK awarded a research grant of £57,300.56 to Nottingham University Hospitals NHS Trust in respect of a project for which Glaucoma UK Chairman, Anthony Kin& is lead researcher. In this financial year, a payment of £25,785 was made in respect of the ongoing project. Statement of Public Benefit Glaucoma UK exists to raise awareness of the risks of glaucoma, support people to live well with the condition and fund research into the causes, prevention and treatment of the disease. Risk management and internal control When reviewing the charity's objectives and planning future activities, the trustees refer to Charity Commission guidance on public benefit and can confirm that all Glaucoma UK'S activities are undertaken to further our charitable purposes for public benefit, in accordance with Section 17 of the Charities Act 2011. Overall responsibility for the charity's risk management lies with the Board of Trustees, with formal assessment and review delegated to the Finance and Governance Committee. A risk register is submitted by the Chief Executive on a quarterly basis which identifies current and new risks, rates each in terms of likelihood• probability and velocity and identifies appropriate controls and mitigations.

Glaucoma UK Trustees, Annual Report 2023 - 24 51 The trustees have assessed the major risks to which Glaucoma UK is exposed as follows: Investment failure All investments are at risk of sustained and long-term fall in value of funds held in stock markets. The Board of Trustees seeks to offset risks to its investment holdings in the following ways: Investments held in a professionally managed portfolio. Access to live online investment reports. Quarterly reporting to Finance and Governance Committee and annual meeting with investment managers. Investment Policy reviewed annually. Minimum of three months, operating costs held in cash account. Lack of income diversity Although work to diversify income Stream5 continues, the charity is still heavily dependent on gifts in wills, with legacy income representing 65% of total income in the year 2023-24. The following measures are in place to mitigate this risk.. Income position monitored via monthly management account5 and quarterly reports to the Finance & Governance Committee. Cash flow forecasts and legacy gift pipeline report presented at each quarterly Finance & Governance Committee meeting. Reserves holding and investment portfolio with diversified risk to cover medium and longer-term income shortfalls. Staff capacity increased in the fundraising department in 2023 to create additional resource for income diversification and speed up the administration of legacy gifts. New Theory of Change framework and outcome reporting mechanisms in place to better demonstrate the charity's impact and secure higher levels of corporate sponsorship, major donor funding and charitable trust support. Compromised IT systems and cyber security failure In response to increasing levels of cybercrime in the UK and a tightly regulated data protection environment, the following mitigations are in place.. Retained professional support for staff training and regular system security monitoring. Cyber Essentials accreditation achieved in June 2024. Cyber training programme in place for all staff. 'reCAPTCHA' technology installed on the Glaucoma UK website shop to prevent automated transactions. Daily offsite backup and office-hours support contract in place. Appropriate policies in place (Information Governance, ICT, Data Protection) and subject to annual review.

52 Structure and management Cyber insurance in place, with support for post-incident management. Multi Factor Authentication enforced on all available systems. Strict access controls to ensure that only authorised personnel can access sensitive information and systems. Regular software updates and patch management to protect against known vulnerabilities. Intrusion Detection and Prevention Systems (IDPS) to monitor network traffic for suspicious activity and prevent potential threats. Firewall, antivirus and anti-malware software in place. Encryption of sensitive data. Committee. The Chief Executive reviews all other staff salaries annually and makes recommendations to the Board as part of the annual budget setting proce5S. When setting salaries, trustees are guided by a remuneration policy that considers factors such as pay comparability (benchmarked within our own sector but also referencing public and private sector pay increase estimates), affordability, sustainability, and appropriateness. Glaucoma UK aims to set salaries at a level where the ratio between the highest and lowest full-time equivalent is below 4.5:1 and the ratio between the highest and median (midpoint) salary is less than 3.5:l. As at l August 2024 these ratios were 3.6:l and 2.7..1 respectively. Remuneration policy The trustees consider the Chief Executive and the Senior Management Team as comprising the key management personnel, in charge of directing, controlling and operating the charity on a day-to-day basis. All trustees give of their time freely and no trustee remuneration was paid in the year. Trustees are required to disclose all relevant interests and withdraw from decisions where a conflict of interest arises. The pay of the charitys Chief Executive is reviewed annually by the Board Chair and Finance and Governance

laucoma UK Trustees, Annual Report 2023 - 24 53 Glaucom" UK Glauco" you

54 Statement of trustee responsibilities Statement of trustee responsibilities The trustees are responsible for preparing the Trustees, Annual Report including the strategic report and financial statements in accordance Wfth applicable law and United Kingdom accounting standards (UK generally accepted accounting practice). Company law requires the trustees to prepare financial statements which give a true and fair view of the state of affairs of the charitable company and of the incoming resources and application of resources, including the income and expenditure of the charitable company for that period. In preparing these financial statements, the trustees are required to: select suitable accounting policies and then apply them consistently? observe the methods and principles in the Charities SORP; make judgments and estimates that are reasonable and prudent; state whether applicable UK accounting standards have been followed, subject to any material departures disclosed and explained in the financial statements. prepare the financial statements on the going concern basis unless it is inappropriate to presume that the charitable company will continue in business. The trustees are responsible for keeping proper accounting records that disclose with reasonable accuracy at any time, the financial position of the charitable company and enable them to ensure that the financial statements comply with the Companies Act 2006. They are also responsible for safeguarding the assets of the charitable company and hence for taking reasonable steps for the prevention and detettion of fraud and other irregularities.

Glaucoma UK Trustees, Annual Report 2023 - 24 55 The trustees are responsible for the maintenance and integrity of the corporate and financial information included on the charitable company's website. Legislation in the United Kingdom governing the preparation and dissemination of financial statements may differ from legislation in other jurisdictions. In so far as the trustees are aware: there is no relevant audit information of which the charitable company's auditor Is unaware. and the trustees have taken all steps that they ought to have taken to make themselves aware of any relevant audit information and to establish that the auditor is aware of that information. The Trustees, Annual Report is approved by order of the Board of Trustees, and the Strategic Report (included therein) is approved by the Board of Trustees in their capacity as directors on 20th February 2025 and signed on their behalf by Professor Anthony Klng Chair

56 Independent auditors, report Independent auditors, report We have audited the financial statements of The International Glaucoma Association Limited for the year ended 31 July 2024 on pages 60 to 75. The financial reporting f ramework that has been applied in their preparation is applicable law and FRS 102 (effective January 2015), as well as the Statement of Recommended Practice for Charities (effective January 2015). This report is made solely to The International Glaucoma Association's members and Board of Trustees, as a body, in accordance with Section 144 of the Charities Act 2011, and regulations made under Section 154 of that Act, as well as Section 44 (1) ( c ) of the Charities and Trustee Investment (Scotland) Act 2005 and the Charities Accounts (Scotland) Regulations 2006. Our audit work has been undertaken so that we might state to the charitable company's members and Council of Management those matters we are required to state to them in an auditors, report and for no other purpose. To the fullest extent permitted by law, we do not accept or assume responsibility to anyone other than the charitable company and the charitable companls trustees as a body, for our audit work, for thi5 report, or for the opinions we have formed. Respective responsibilities of trustees and auditors As explained more fully in the Trustees, Responsibilities set out on pages 54 and 55, the trustees (who are also the directors of the charitable company for the purposes of company law) are responsible for the preparation of the financial statements and for being satisfied that they give a true and fair view. We have been appointed as auditors under Section 44 (1) ( c ) of the Charities and Trustee Investment (Scotland) Act 2005 and the Charities Accounts (Scotland) Regulations 2006 and report in accordance with regulations made under those Acts. Our responsibility is to audit and express an opinion on the financial statements in accordance with applicable law and International Standards on Auditing (UK and Ireland). Those standards require us to comply with the Auditing Practices Board's Ethical Standards for Auditors.

Glaucoma UK Trustees, Annual Report 2023 - 24 57 Scope of the audit of the financial statements An audit involves obtaining evidence about the amounts and disclosures in the financial statements sufficient to give reasonable assurance that the financial statements are free from material misstatement, whether caused by fraud or error. This includes an assessment of whether the accounting policies are appropriate to the charitable company's circumstances and have been consistently applied and adequately disclosed; the reasonableness of significarbt accounting estimates made by the trustees" and the overall presentation of the financial statements. In addition, we read all the financial and non-financial information in the Trustees, Annual Report to identify material inconsistencies with the audited financial statements and to identify any information that is apparently materially incorrect based on, or materially inconsistent with, the knowledge acquired by us in the course of performing the audit. If we become aware of any apparent material misstatements or inconsistencies, we consider the implications for our report. irregularities. The extent to which our procedures can detect irregularities, including fraud, is detailed below: Gaining a full and extensive knowledge of the entity, environment and the regulatory framework to which it must abide by. Evaluating and assessing the extent to which the entity's internal systems are adhering to these as well as gaining a full and comprehensive understanding of the entity's activities and effectiveness of its control environment (including those in place to identify and prevent fraud). We achieved this by carrying out the following: Enquiry of the detailed communication with management and those charged with governance. Reviewing internal systems and controls. Reviewing financial statement disclosures and compliance with applicable laws and regulations. Irregularities, including fraud, are instances of non-compliance with laws and regulations. We design procedures in line with our responsibilities, outlined above, to detect material misstatements in respect of Opinion on financial statements In auditing the financial statements, we have concluded that the trusteesl directors, use of the going concern basis of accounting in the preparation of the financial statements is appropriate.

58 Independent auditors, reporr Based on the work we have performed, we have not identified any material uncertainties relating to events or conditions that, individually or collectively, may cast significant doubt on the entity's ability to continue as a going concern for a period of at least twelve months from when the financial statements are authorised for issue. Our responsibilities and the responsibilities of the trusteesldirectors with respett to going concern are described in the relevant sections of this report. In our opinion, the financial statements: give a true and fair view of the state of the charitable company's affairs as at 31 July 2024 and of its incoming resources and application of resources, including its result, for the year then ended. have been properly prepared in accordance with the Financial Reporting Standards 102 (effective January 2015); have been prepared in accordance with the requirements of the Companies Act 2006, and Section 44 (1) ( c ) of the Charities and Trustee Investment (Scotland) Act 2005 and the Charities Accounts (Scotland) Regulations 2006. Matters on which we are required to report by exception We have nothing to report in respect of the following matters where the Companies Act 2006, the Charities Act 201 l and the Charities Accounts (Scotland) Regulations 2006 requires us to report to you if, in our opinion: the information given in the Report of the Board of Trustees is inconsistent in any material respect with the financial statements. or the charitable company has not kept adequate accounting records. or the financial statements are not in agreement with the accounting records and returns; or we have not received all the information and explanations we require for our audit. Ros3'111.? Turner (Feb 21, 20￿ 14..42 Gmri Rosanna Turner For and on behalf of Xeinadin Audit Limited, Registered Auditors 12 Conqueror Court, Sittingbourne MEIO SBH Eligible to act as an auditor in terms of Section 1212 of the Companies Act

59 Financial statements for the year ended 31 July 2024 Glaucoma UK (the operating name of the International Glaucoma Association Limited). Charity No. 274681, in Scotland No. SC041550. Company No. 1293286

60 Financial statements for the year ended 31 July 2024 Statement of financial activities incorporating an income and expenditure account For the year ended 31 July 2024 2024 Total 2023 Total Restricted Unrestricted Note Income Donations, legacies and subscription5 Investment income 47,571 41,605 1,740,348 1,787,919 1,464,956 158,329 199,934 181,738 Charitable activities Professor of Ophthalmology for Glaucoma and Allied Studies at UCL Influencing policy & practice Corporate support Lottery Christmas cards 9,130 254,950 2,500 9,130 254950 81.950 10,484 87,975 79,450 2,149 18,256 17,541 4,721 6,858 1,190 1,190 2,178 2,002.294 &35&050 1,773.879 18256 721 Other income Total income Expenditure on: Raising funds Finance and support Cost of generatir¢g funds 355,756 3.848 14,438 18,286 18,211 256,684 274,895 21059 271,122 293.181 22,614 198,825 221,439 Expenditure on charitable attivities Raising awareness Providing support Supporting research and development Influencing policy and practice Christmas cards 244,342 244,342 119.780 611,063 615290 694,754 354,117 457,490 453,935 254,221 465,154 261.538 2,288 2288 1.778 1.740.926 2.077.745 1.753,224 (7,710) 280,305 12,945 439.908 (124,368) 720213 (111,423) 4,227 103,373 210,933 Total expenditure Realised losses on investment assets 336.819 Net Income 18,937 92,205 111,142 261.368 Unrealised losses on investment assets 347,703 609,071 Net incoming resources before transfers Gross transfer between funds Net movement in funds Reconciliation of funds 111,142 609,071 720213 (111,423) Total fund5 brought forward Total funds carrled forward 1,518,802 6,528,945 4047,747 8,159,170 1 629 944 7 138 016 767 960 8 047 747 All of the results above are derived from continuing acti¥lties. There were no other recognised rdins or losses other than those stated above. Movemerts in fund5 are disc105ed in Note 17 to the financial 5t3ternents. Glaucoma UK (the operating name of the International Glaucoma Association Limited)

Financial ststements for the year ended 31 July 2024 61 Balance sheet As at 31 July 2024 Charity No. 274681 Scotland No. SC041550 Company No. 1293286 2024 2023 Note Fixed assets Tangible fixed assets Investments io 806 3,210 6.860,720 li 7.481,765 Total fixed assets 7,482,571 6,863,930 Current assets Stock 12 3,656 Debtors 13 20 1,692,539 554,254 1,450,507 631,742 Cash at bank and in hand 2,246,793 2,085,905 Liabilities Creditors.. amounts due within one year 14 19, 20 798,304 647,532 Net current assets 1,448,489 1,438,373 Total a55ets less cur￿Tht liabilities Creditors.. amounts due after more than one year 8,931,060 8,302,303 15, 20 163,100 254,556 Net assets 16 8,767,960 8,047 747 Funds 17 Restricted funds 1.629.944 1.518,802 Unrestricted funds Designated funds General funds 4,340,791 2,797,225 4,387,968 2,140,977 Totsl funds 8,767,960 8,047,747 Approved by the board of trustees of the Intemational Glaucoma Association Llmited and slgned on Its behalf by Mr Raymond Spendiff, Trustee. eb 21, 2025 16..47 GM Glaucoma UK Ithe operatinB name of the International Glaucoma Association Limited)

62 Financial statements for the year ended 31 July 2024 Statement of cash flow For the year ended 31 July 2024 Cashflow5 from operatlng activities: 2024 2023 Net cash provided by (used in) operating activities {95￿29) (48,332) Cashflows from investing activities Dividends and interest from investments 199.934 181,738 Purchase of property, plant and equipment Proceeds from sale of property, plant and equipment Proceeds from Sale of investments (1208) 452 225,476 (167,503) Purchase of investments (181.719) Net cash provided by (used in) investing activities 17.459 239,711 Change in cash and cash equivalents in the reportingperiod Cash and cash equivalents at the beginning of the reporting period Cash and cash equivalents at the end of the reporting period (7&070) 191,379 631473 441,094 554,403 632,473 Increase/Decrease in cash balances (74070) 191,379 Recon¢iliatlon of net movement in funds to net ¢ash flow from operating activities Net movements in funds ft)r the reporting period (as per the statement of financial artivities 720,213 (111,423) Adjustments fop. Depreciation Dividend5 & interest from investments 3,160 12,931 (199,934) (439.908) 3.656 (181,738) 132,078 Loss/(Profit) on sale of investments (Increase)IDecrease in stocks (Increase)IDecrease in debtors Increa5el(Decrease) in creditors (242.032) 59?16 (335,432) 435,141 Net cash pmvided by (used in) operating activities Anatysis of cash and cash equivalents (95,529) (48,332) Cash in hand 554,254 631.742 Investments Capital account 149 731 554,403 632,473 Glaucoma UK (the operating name of the International Glaucoma A550ciation Limited)

Notes to the financial statements for the year ended 31 July 2024 63 Notes to the financial statements For the year ended 31 July 2024 1. Accounting policies a) The financial statements have been prepared under the historical c05t convention, as modified by the revaluation of fixed asset investments, and in accordance with applicable accounting standards and the Companies Act 2006. They follow the recommendations in the Statement of Recommended Practice, Accounting and Reporting by Charities. The accounting standards policies have been prepared under Financial Reporting Standard 102, the Financial Reporting Standard applicable in the UK and Republic of Ireland, (United Kingdom Generally Accepted Accounting Practice) and SORP 2019.The Trustees confirm that the charitable company is a public benefit entity. The accounts are prepared in sterling pound and rounded to the nearest £1. The charity is a company limited by guarantee from 627 voting members incorporated on 15 July 1976 and registered as a charity on 20 December 1977. The objects of the charity are defined by its Articles of Association updated in March 2012. The International Glaucoma A550ciation (IGA) is constituted both a5 a charity and as a company limited by guarantee and as such the members of its council are director5 for the purposes of company law and trustees of the charity for the purposes of charity law. The powers of the council and the permitted attivities of the association are described in it5 governing document. which is the Articles of Association. The International Glaucoma Association registered office is Woodcote House, 15 Highpoint Busines5 Village, Henwood. Ashford, Kent, TN24 8DH. The International Glaucoma Associatiori 15 registered as a company in the United Kingdom. due. The financial statements have therefore been prepared on a going concern basis. b) Voluntary income received by way of subscriptions. donations and gifts are included in full in the Statement of financial attivities when receivable. ) Income from legacies is accounted for on a receivable basis, recognised when entitlement to the income has been established and it is probable that Glaucoma UK will receive the amounts ascertained. This treatment is within SORP 2019 and Financial Reporting Standard 102 the Financial Reporting Standard applicable in the UK and Republic of Ireland (United Kingdom Generally Accepted Accounting Practice). Sales income represents sale of good5 excluding VAT where appropriate. Investment income is accounted for on an accruals basis. d) Restricted funds are to be used for specific purpose5 35 laid down by the donor. Expenditure which meets these criteria is charged to the fund. e) Unrestricted funds are donations and other incoming resources received or generated for general charitable purposes. f) Designated funds are unrestricted fund5 earmarked by the Board of trustees for particular purposes. Within these funds is money awarded as grants. funding a range of research projert5 to develop more effective method5 of glaucoma diagnosi5 and treatment. In assessing the charitys status as a going concern, the trustees have considered a range of information in relation to the financial year ahead, including the current status of the UK economyj the charity's cash resource5 and known liabilities. The charitys 3-year financial plan for the period 2024-2027 shows the harity to have adequate resources to continue operating an effective service for at least 36 months and to meet its obligations a5 they fall g) Costs of generating funds relates to the cost5 incurred in fundraising activities. h) Critical accounting judgements are used within these accounts as follows.. Residual legacy incorne debtors are valued at 85% of the expected value of the legacy when certain criteria are met and receipt Is probable. Residual legacies that are over the material Glaucoma UK (the operating name of the International Glaucoma Association Limited)

64 Notes to the financial statements for the year ended 31 July 2024 l. Accounting policies (continued) amount set by Glaucoma UK at £300,000 are recorded in the accounts at 100% once criteria is met and receipt is probable. n) The fixed assets are held at cost less depreciation and any impairment. Depreciation is provided at rate5 calculated to write down the cost of each asset to its estimated residual value over it5 expected useful life. The depreciation rates in use are as follows- The 5UPPOrt and governance costs are re- apportioned by staff time as explained in note (i). The staff costs attributed to each activity are reviewed each year when the new budget is set. Fixtures, fittings and equipment 2 Computers 33% Items of equipment are capitalised where the purchase price exceeds £1,000. Depreciatio costs are allocated to activities on the basis of the use of the related assets in those activities. Assets are reviewed for impairment if circumstances indicate their carrying value may exceed their net realisable value and value in Use. Resources expended are recognised in the period in which they are incurred. Resources expended include attribkjtable VAT which cannot be recovered. i) Resources expended are allocated to a particular activity where the c05t relates directly to that activity. However, the cost of overall direction and administration of each activity. comprising the salary and overhead costs of the central function which includes finance and support and governance is apportioned on the following basi5 which is an estimate based on staff time of the amount attributable to each activity. o) Stocks are stated at the lower of cost and net realisable value. In general, cost 15 determined on a first in first out basis. Net realisable value is the price at which stocks can be sold in the norrnal course of business after allowing for the costs of realisation. Provision is made where necessary for obsolete, slow moving and defettive stock. During the year the charity recetved donated items that have been stated at fair value. Support costs Cost of generating funds Expenditure on charitable activities Research 20% 73% p) The charity contributes to a defined contribution pension scheme. The assets of the scheme are held separately from those of the charity in an independently administered fund. Contributions payable are charged as an expense in the SOFA (Statement of financial activities) within staff costs then shared between the SOFA categories by staff time within these artivitie5. j) Grants awarded are charged to the Statement of Financial Activities in the year in which they are awarded and are subject to receipt of progress reports. k) Governance costs are the costs associated with the governance of the charity. including constitutional and statutory requirements and cost5 associated with the strategic management of the CharIt￿S activities. q) Financial instruments assets and liabilities are valued in the accounts at fair walue and are subsequently carried at amortised c05t shown in Note 20. l) Monetary assets and liabilities in foreign currencies are translated into sterling at the Bank of England exchange rate for that day. r) Debtors are stated at their net realisable value after allowing for bad and doubtful debts. The recoverability of debtors is reviewed at year end and provision is made, either general or specific, based on value, age and composition of our year end debtor balance. m) Investments held as fixed assets are revalued at market value at the balance Sheet date. The Trustees consider that market value is a reasonably accurate representation of the fair value. The gain or loss for the period 15 taken to the statement of financial atttvities. 5) Trade creditors are recognised in the accounts at its settlement amount when there is a present obligation to the entity arising from past events. Glaucoma UK (the operating name of the International Glaucoma A550ciation Limited)

Notes to the financial statements for the year ended 31 July 2024 65 2. Voluntary income 2024 Restrirted 2023 2024 2023 Restricted Unrestrlcted Unrestrirted 2024 Total 2023 Totsl Donations and subscriptions 41.139 2.567 21S,620 235.920 256.759 256,028 Corporate donations 2243 14,649 2,243 14,649 Legacies Total 6.432 35,449 l.S22.485 1,178,520 7￿28.917 1,213,969 47A71 38,016 1,740J48 1.429,089 1,7È7,919 1,484,646 3. Investment income 2024 Restricted 2023 2024 2023 Restricted Unrestricted Unrestricied 2024 2023 Total Interest 504 1.438 504 Dividend5 41.605 38,024 156WI 143,210 19&496 181,234 Total 41,605 38,024 158J29 143,715 199,934 181.738 4. Incoming resources from charitable activities 2024 2023 2024 2023 Restricted Restritted Vnrestrieted Unrestricted 20Z4 Total 2023 Total Professor of Ophthalmology for Glaucoma and Allied Studies at UCL 9,130 10,484 9,130 10,484 Influenting policy & practice 254950 87,975 254,950 87,975 Corporate support 79050 81,950 Lottery 18256 17.541 1&256 17,541 Christmas cards 4721 6.858 4,721 6,858 Other income 2,178 2.178 264580 94459 103,617 21577 370,197 125036 * Include5 UK and Eire Glaucoma Society Glaucoma UK (the operating name of the International Glaucoma Association Limited)

66 Notes to the financial statements for the year ended 31 July 2024 5. Total Expenditure Cost of Raising Providing Supporting generating awareness support research and funds development Staff costs (Note 7) 164,591 103,907 333,198 62,487 Research (Note 8) 363.222 Raising funds 36,966 Helpline service 21,801 Outreach services 11,108 Event5, advertising and media 80,513 3,348 Patient education 105,006 Christmas cards 2,288 Premise5 & administration 16,005 2,726 Finance & professional 22,059 2,645 Expendtture 225,904 200,425 474,461 431.080 Finance & sUPPOrt reallocated 60,509 38,200 122,497 22,972 Expenditure including Finance & Support 286,413 238,625 596,958 454,052 Governance reallocated 9.056 5,717 18,332 3,438 Total Expenditure 295,469 244.342 615290 457.490 Glaucoma UK (the operating name of the International Glaucoma Association Limited)

Notes to the financial statements for the year ended 31 July 2024 67 Influencing policy and practlce Finance and Governance support 2024 Total 2023 Total 179.725 108,246 23,081 975535 835,770 363,222 408,660 36,966 33,762 21,801 6,685 14,419 25,527 10230 195,049 5,989 284899 122,313 105.006 lo￿27 2288 £043 146,90S 4,088 169.724 201,714 63,585 4,788 93.077 119,526 389,193 318,736 37,946 2.077.745 1,753,224 66,073 (318,736) 8,485 455,266 46,431 2.077.745 1,753,224 9,888 (46,431) 465,154 077,745 1,753,224 Glaucoma UK (the operating name of the International Glaucoma Association Limtted)

68 Notes to the financial statements for the year ended 31 July 2024 6. Net (outgoing)[Incoming resources This is stated after chargingjcrediting: 2024 2023 Depreciation charge for the year- owned a55ets Auditors, remuneration: audit other services Trustees expenses Investment managers fee 3.160 12,931 6,300 4,319 2,161 12,006 4.300 1,348 3,143 18.139 Trustees expenses represent the travel and subsistence costs of 6 trustees for 9 meeting £2,161 (2023: £3,143). Wrthln 2024 some Trustees meetlngs were stlll held virtually. Donations totalling £664 were receNed from Trustees (2023.. £597). No trustees receNed remuneration for their services during the financial year 7. Staff costs and numbers Staff costs were as follows: 2024 2023 Salaries and wages Social security costs Pension contributions 846.577 87,068 47￿90 975235 726,053 73.727 35,990 835,770 Onty one member of key rnanagernent personnel earned £80,000 or more in the year. 2024 No. 2023 No. £70,000- £80,000 £80,000- £90,000 Pension contributions in respert of the above £80,OIXI- £90,000 fvll-time employee totalled £4.134 (2023: £3,900). Nl contributions in respect of the above £80,000490.000 employee totalled £l0.155 (2023: £9,724) The calculated unspert staff holiday entttlement at year end was £2,907 (2023.. £14,430). The charty contributes to a Royal London defined contribution pension scheme for employees. The W Management Personnel having authority and responsibility for plannin& direrting and controS1ing the actmties of Glaucoma UK are the Senior Management Team. The total of Key Management personnel. employee benefits and remuneration V￿re £381,319, (£315,439 23-24) When setting 5alarie5, tru5tee5 are guided by a remuneration policy that considers fattors such as pay compardbility (benchmarked withln our own sector but also referenclng public and private sector pay increase estimates). affordability. sustainability. and appropriateness. Glaucoma UK aims to set salaries at a level where the ratio betsveen the highest and lowest fvll-time equivalent is below 4.5..1 and the ratio between the highest and median (midpoint) salary 15 les5 than 3.5:1. As at l August 2024 these rntios were 3.6:l and 2.7:1 respettively. Glaucoma UK (the operating name of the International Glaucoma Association Limited)

Notes to the financial statements for the year ended 31 July 2024 69 7. Staff costs and numbers (continued) The average weekly number of employees (full-time equivalent) during the year was: 2024 No. 2023 No. Cost of generating funds Patient information and support Professional information and support Campaigning and awareness Research 3.95 2.46 9.57 2.52 1.16 5.35 1.49 1.27 0.38 Governance Finance and Support costs 0.52 0.49 2.86 22.88 1.95 18.53 The actual number of staff (including part time and full time) at July 2024 was 27 (2023: 26) at year end. 8. Grants Awarded 2024 2023 University College London's Institute of Ophthalmology- Glaucoma UK Chair Fund Fight for Sight Cardiff University London School of Hygiene and Tropical Medicine Queens University Belfast University of Plymouth Moorfield5 Eye Hospital NHS Foundation Trust Anglia Ruskin University Ulster University Manchester University NHS Foundation Trust Liverpool University University of Birmingham Grants underspent by researchers 74673 73,389 22,433 49,293 24,760 99,328 48,287 96,082 10,000 99,919 49.791 50.000 99.652 10.813 363222 14,912 408.660 These grants were awarded in accordance with the Glaucoma UK grants policy, and were awarded to fund research into the diagnosis and treatment of glaucoma. The negative figure represents an underspend by researchers on grants awarded in previous years Glaucoma UK (the operating name of the International Glaucoma Association Limited)

70 Notes to the financial statements for the year ended 31 July 2024 9. Taxation The charity is exempt from corporation tax and income tax as all its income is charitable and applied for charitable purposes l O. Tangible fixed assets Computer equipment Total Cost At the start of the year Additior¢5 in the year Disposals in the year At the end of theyear 37,185 1,208 452 37.185 1208 452 37,941 37,941 Depreciation At the start of the year Charge for the year Disposals in the year At the end of the year 33,975 3,613 453 37,135 33,975 3.613 453 37.135 Net book value At the end ot the year 11. Investments 2024 2023 Rathbones Core Investments fund for charities At 1st August 2024 Additions at historic cost Disposal proceeds Realisedlosses 859,989 181,719 7,050,040 167,503 (225,476) (7,710) 124,368 Unrealised gainsllosses Market value at the end of the year Cash held as part of portfolio 439.908 7.481￿76 149 6,859,989 731 Total 7 481765 6 860 720 Glaucoma UK (the operating name of the International Glaucoma Association Limited)

Notes to the financial statements for the year ended 31 July 2024 71 I l. Investments (continued) Investment management costs were £12,006 (£18,139- 2023) Glaucoma UK Ltd, Glaucoma International Ltd. Glaucoma Europe Ltd, and Glaucoma Association Ltd are dormant companies historically held by Glaucoma UK (the operating name of the International Glaucoma Association Limited) in order to protert the company identity and to give future flexibility in terms of the charlty name. International Glaucoma Association hold IO0% of all the dormant companies. Glaucoma UK Limited number 04323894 total shareholder funds £1. Glaucoma Europe Limited number 04591043 total shareholders funds £1. Glaucoma International Limited number 04323990 total shareholders funds £1. Glaucoma Association Ltd number 05316092 shareholders funds £1. 12. Stock 2024 2023 Goods for resale 13. Debtors 2024 2023 Trade debtors Legacy debtors Prepayments and accrued income 47,102 1,619J63 24074 1&956 IA15.702 115,849 1.69 39 507 Glaucoma UK (the operating name of the International Glaucoma Association Limited)

72 Notes to the financial statements for the year ended 31 July 2024 14. Creditors: amounts due within one year 2024 2023 Trade creditors Obligations under grant agreements Funds held as agent Accruals & Deferred income 166J96 403.061 28214 194789 65,276 282,884 32,205 264,469 Vat liability 2,698 647 532 Funds held as agent represent those held for UKPGS, for which Glaucoma UK provides administration and infrastrutture support as shown in note 19. 15. Creditors: amounts due after one year 2024 2023 Obligations under grant agreements 164100 254,556 16 100 254 556 16. Anatysis of net assets between funds Restricted Designated funds funds General funds Total funds£ Tangible fixed assets Investments 806 1,629,944 4,340,791 1,511,030 7.481,765 1,448,489 1.444489 Net current assets Creditors: amounts falling due after more than one year 163,100 163.100 Net assets at the end of the year 1629 944 40 791 2 797 25 Glaucoma UK (the operating name of the International Glaucoma Association Limited)

Notes to the financial statements for the year ended 31 July 2024 73 17. Movements in funds At the start of Incoming the year resources Other Outgoing gains and resources losses Transfers At the end of the year Restrirted funds: Chair fund 1,437,760 53,134 (78,521) 92,205 1,504,578 North Eastfund 9.815 (3,665) (8,701) 6,150 Research fund 8,701 Folkestone fund 3,733 (440) 3,293 Children and Young people'5 Support fund London fund 8,784 1,587 9,321 47,802 (122) 8.662 1,587 5.918 75.223 Scottish Optom fund UK & Éire Glaucoma Society 50th Anniversaryfund (3.403) 254,951 (227,530) 38,970 14,437 24533 Total restrlcted fund$ 7￿18￿•2 355,756 336.819 92.205 1.629.9H Unrestricted funds.. Designated funds.. Income Endowment 22,906 22,906 Equipment Replacement and Infrastructure fijnd 460,000 (25,255) 434745 Research Investment fund 3,900.0¢)O (21,922) 3078,078 West Yorkshire Support fund 5,062 5.062 Total designated fvnds 4,387,968 (47,177) 4340.791 General fvnds 2,140,977 2,002,294 (1,693,749 347,703 797.225 Total unrestrirted funds 6￿28,945 2002294 (1,740,926 347.703 7.138.016 Totsl funds .047 747 2.35&050 2.077 745 8.767.960 Glaucoma UK (the operating name of the International Glaucoma Association Limited)

74 Notes to the financial statements for the year ended 31 July 2024 17. Movements in Funds (continued) Purpose5 of restrirted funds The UKEGS fund compri5e5 money for the work of the United Kingdom and Eire Society (UKEGS), a national scientific society that operates under the aegis of Glaucoma UK. The 50th anniversary research fund comprises income donated as part of our 50th anniversary appeal. It is to be used towards the Research Fellowship award to support research into glaucoma to improve the lives of people affected by glaucoma. The designated income endowmentfund represents the donation of share5 which form the basis of a stock market portfolio, which will eventually provide for the running costs of the association. The Chair fund is used to fund the post of Professor of Ophthalmologrf for Glaucoma and Allied Studies at University College London. The North East fund wa5 established following receipt of a legacy and is restritted to supporting our work in the North East of England. The Research fund represents donation5, charitable trust and legacie5 income received specifically to fund glaucoma research. The fund wa5 drawn on throughout the year as detailed on Note 8. The Folkestone fund comprises legacy income restritted to work in Folkestone. The Children and Young People's Support fund comprises income donated for services for young people affected by glaucoma and their families and carers. It aims to help us better understand their particular support needs and deliver appropriate services in response. The London fund 15 restricted to the London area and has been used mainly for awareness raising and support work with BAME communities at greatest risk of glaucoma sight Ios5. The Scottish Optom training fund is charitable trust income earmarked for eye drop adherence training for optometrists acr055 Scotland. Following delay5 due to Covid-19 and changes to the professional training landscape in the intervening period, we have now developed new training courses for optometrists and other staff in optical practice5. We are hoping to get thi5 accredited by the GOC and roll out the training over the next two years. The designated Equipment Replacement and Infrastructure fund is held to cover the cost of equipment replacement, infrastructure development, premises costs and dilapidations. The designated Research Investment fund aims to produce a reliable income stream specifically to fund the charity's research priorities in the years ahead. The West Yorkshire Support fund was set up by the trustee5 from a legacy our charity received which the legator expressed interest in the funds being used towards any general activities we have in the West Yorkshire area. This aligned with Glaucoma UK setting a new project this year for funds to be awarded for establishing or developing Glaucoma support groups in areas of greatest need or with greatest potential for impatt. 18. Operating lease commitments The charity had annual commitments at the year end under operating leases expiring as follows: Property 2024 2023 Within one year Within l - 2 Years 19034 34,000 Glaucoma UK (the operating name of the Internation31 Glaucoma A5so¢iation Limited)

Notes to the financial statements for the year ended 31 July 2024 75 19. Related parties In 2022 Glaucoma UK awarded a grant of £57,300.56 to Nottingham University Hospital which the lead researcher is Professor King. This was duly disclosed and recorded. In this financial year, the research project has started, and an initial payment of £25.785 for this grant was paid to Nottingham University Hospital. This leaves an outstanding balance due to Nottingham University Hospital of £31,515.56. Included in Note 14 are funds due to related parties held for the UK Paediatric Glaucoma Society (UKPGS) of which we provide administration and infrastructure support. One Glaucoma UK Trustee is also a UKPGS trustee during the financial year. rinancial Statement of UKPGS 2024 2023 Income Expenditure Closing balance Balance brought forward 15.720 26,385 (19.710) (18.694) (3.990) 7.691 32204 24.514 Total funds held 28214 32,204 20. Financial Instruments Financial Debt instruments measure at amortised cost 2024 2023 Trade debtors Legacy debtors Prepayments and accrued income 47.102 1,619,363 24074 18,956 1,315,702 115,849 539 1450 507 Financial instruments measured at amortlsed cost Trade creditors Obligations under grant agreements Funds held as agent Accrua15 & Deferred income Vat & National Insurance liability 164396 566,161 28214 196,789 3￿44 65,276 537,440 32,205 264,469 2,698 902 088 Glaucoma UK (the operating name of the International Glaucoma Association Limited)

Glaucoma UK Celebrating 50 years 1974 - 2024 Glaucoma UK Woodcote House 15 Highpoint Business Village Henwood Ashford Kent TN24 8DH Phone: [phone] Email: [e-mail] Website: glaucoma.uk Glaucoma UK is the operating name of the International Glaucoma A550ciation Limited. Charity registered in England and Wales No. 274681 and Scotland No. SC041550 Company Registered in England & Wales no. 1293286