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2023-10-31-accounts

CAMBRIDGE EYE TRUST

Report and Accounts October 2023

Contents
Page
Report of the trustees 1 to 4
Statement of financial activities 5
Cash flow statement 6
Balance sheet 7
Notes 8
Examiner’s report to the 9
trustees

Cambridge Eye Trust

Web address

Trustees' Annual Report

The trustees present their report for the year to 31st October 2023.

Objectives and activities of the charity

The object of the Cambridge Eye Trust, as set out in its governing document, is to advance the education of the public in the science of ophthalmology, in particular but without limitation by: -

  1. i. establishing and maintaining the Cambridge Ophthalmological Symposium (to be held periodically and to be open to specialists or students of Ophthalmology or related sciences), for the study, discussion and reading of papers on topics related to the science and practical development of Ophthalmology and all allied subjects; including the provision of lecturers and other speakers for the Symposium and the publication of reports of the proceedings; and

  2. ii. supporting the research of lecturers and researchers in the field of Ophthalmology.

The advancement of research and education of the public in the science of ophthalmology is achieved by:-

Cambridge Eye Trust

Page 1

Achievements and performance

The trustees continued to support the programme of research set up in September 2017 in the Centre for Brain Repair by Professor Keith Martin, who moved in 2019 to Melbourne Australia to head the Centre for Eye Research Australia. This programme ‘Enhancement of Optic Nerve Regeneration by modulation of Integrins’ aims to promote orderly and controlled regeneration of axons in the optic nerve without reliance on oncogenes, offering hope of restoring vision to those blind with optic nerve disease. The Trust continued the funding in 2023, allowing two PhD students to complete their research work in Cambridge and supporting a previous member of the team, who is currently working in clinical ophthalmology and basic science research in this field in the USA.

In 2020, the Trustees received a request from Patrick Yu Wai Man, Professor of Ophthalmology at the University of Cambridge, for an OCT (Optical Coherence Tomography) machine to use in a dedicated eye research facility, in order to study patients undergoing a research trial of gene therapy for Leber’s Hereditary Optic Neuropathy. After due consideration, the Trust granted a sum of £50,000 to purchase the OCT for the research room. The equipment is also available for other research trials conducted by other members of the Addenbrooke’s Eye Department. OCT is a non-invasive diagnostic instrument used for imaging the retina. The OCT uses an array of light to scan rapidly the eye. These scans are interpreted by the software in the machine and the OCT then presents an image of the tissue layers within the retina. This new diagnostic facility is now widely used in the diagnosis and management of many ocular conditions. The OCT machine is employed in two on-going research studies of gene therapy injections into the eye for optic nerve diseases, conducted by Professor Man.

The Trust also supported a study of the genetic make-up of the cells forming the posterior layer of the vitreous, planned by a team under the supervision of Martin Snead, Director of Vitreo-Retinal Research at Cambridge. Posterior vitreous detachment remains poorly understood. Although the condition is usually a benign event, a significant minority of patients will experience sight-threatening conditions shortly after the detachment of posterior vitreous. The study aims to characterise the gene expression profiles of individual cells and to establish whether there are characteristics which may distinguish pathological from physiological outcomes.

Plans for the future

If new advances are to be made within the field of medical ophthalmology it is vital that clinician scientists are trained in research in this specialty.

This is one of the long-term aims of the charity and the generous funding provided by the Dickerson Fellowship has enabled the Trust to support a joint post-doctorate research post, to work in the current research programme of the University of Cambridge and the

Cambridge Eye Trust

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Ophthalmic Department of Addenbrooke’s NHS Trust.

The Trust guaranteed to support a new post of Senior Clinical Research Associate and in June 2023 the Trust was delighted that a joint appointment between the University of Cambridge, Addenbrooke’s and Addenbrooke’s NHS Trust was made for an individual, who will start in January 2025.

Organisation

The affairs of the charity are conducted by the trustees with the assistance of a freelance conference organiser and a financial adviser (who maintains accounting records and prepares periodic accounts). There are no volunteers apart from the trustees.

The trustees serving in the year and the subsequent period to date were: -

Mr N J Sarkies Mr R Ashby- Johnson Mr Douglas Newman Chairman Professor M Rajan Mr C René Mrs H Shahid

New trustees are selected according to the perceived needs of the charity.

Legal and administrative information

The trust maintains a website for which the address is www.cambridgeeyetrust.org.uk

Cambridge Eye Trust is a charitable trust registered with the Charity Commission for England and Wales under reference 265140.

The governing document is a Scheme dated 16th November 2004. The trustees are incorporated as -

‘The Incorporated Trustees of The Cambridge Ophthalmological Symposium’ so that investments may be held in that name. The principal address for correspondence is:

Wistow, The Green, Hilton, Huntingdon, Cambridgeshire PE28 9NB

Monies are held at CAF Bank Ltd and on deposit with the Charities Official Investment Fund. Some investments are managed by Evelyn Partners Group Ltd of 45 Gresham Street, London EC2V 7BG, an independent adviser authorised and regulated by the Financial Conduct Authority. Investments are held by Evelyn Partners Investment Services Ltd. Other investments have been made in charity authorised investment funds, that are managed for charity investment and as such enjoy advantages. These funds are held directly.

Review of financial affairs

The result for the year to 31[st ] October 2023 was a surplus of £17,852 before a deficit of £14,993 on investments realised and unrealised in the year, as markets deteriorated due to the aftermath of the pandemic and invasion of Ukraine leading to inflation and increased interest rates. The combined surplus was £2,859.

The Symposium had income of some £41,000 which was less than the costs of £51,800. Donations and Gift Aid fell to £6,873 (last year £9,600). Investment income rose by £6,840 to £52,450.

The surplus includes expenditure of £24,297 (last year £7,875) for grants to support research projects and to cover four bursaries for attending the symposium.

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They shall support applications that are received for research projects, and bursaries, subject to their approval. Requests for funding are sent for peer review before being evaluated by the trustees.

The net assets of the trust were £1,673,000 at the October year-end of which £1,574,000 was held in listed investments.

Policies

Investment

The policy of the Trustees is to invest over a long term to provide a total return (being income and capital appreciation combined) that increases over a three-to-five-year period in line with global indices for equity, commercial property and bond investments. It is recognised that the actual returns are likely to be below the index returns, due to management costs and the selection of investments that should mitigate risks. The investments are held in managed funds and investment trusts to achieve both spread and diversity.

The charity does not invest directly in listed companies, and so relies on fund managers to apply ethical investment constraints, which are expected to exclude such as tobacco and gambling activities.

Reserves

The Trustees require reserves sufficient to cover potential deficits from the annual symposium. Any surpluses are accumulated towards supporting educational and research posts for ophthalmologists within the School of Clinical Medicine and for other costs and equipment for research projects.

Public benefit

The trustees have had regard to the guidance on public benefit.

People worldwide with eye problems have benefited directly from advances in medical procedures and instrumentation, discussed during the annual symposia, and from the research associations resulting from contacts made during the residential symposia meetings. Publication of the proceedings extends the knowledge of clinicians throughout the world. Patients will be reassured by reading the information on the Charity’s website and otherwise published, about the procedures that are likely to be applied to them.

If the current research is successful, patients will benefit through the ability of clinicians to prevent detachment of the retina and, if they cannot be prevented, to intervene early in glaucoma, optic nerve, corneal and macular degenerative diseases. In the longer term the aim is to reverse the disease process.

N J C Sarkies. Chairman Cambridge Eye Trust 28[th] December 2023

Cambridge Eye Trust

Page 4

STATEMENT OF FINANCIAL ACTIVITIES Year to 31 October 2023

Year to 31 October 2023 Year to 31 October 2023 Year to 31 October 2022 Year to 31 October 2022
Note Unrestr- Note Unrestr-
icted fund icted fund
£ £
Income from:
Donations including Gift Aid 6,873 9,599
Charitable activities:
Registration fees 31,395 57,463
Sponsorship and grant 10,120 9,000
Investments 52,454 45,611
Total income 100,841 121,674
Expenditure on:
Charitable activities:
Costs of the symposium 51,802 66,549
Bursaries and grants 930 1,395
Research instruments and grants 23,367 7,875
Other- investment management and accountancy 6,890 10,906
Total expenditure 82,989 86,725
17,852 34,949
Net gains or (deficits) on investment assets: 2 (14,993) 2 (95,411)
Net income 2,859 (60,462)
Reconciliation of fund
Total fund balance brought forward 1,669,359 1,729,821
Total fund balance carried forward 1,672,218 1,669,359

Cambridge Eye Trust

Page 5

Printed 09/05/2024

CASH FLOW STATEMENT Year to 31 October 2023

Note
Reconciliation of net income to
net cash flow from operating activities
Net income or (deficit)
Adjustments for:
Deficits on investment assets
1
Dividends and interest from investments
Decrease or (Increaase) in debtors
Decrease or (Increase) in tax recoverable
Increase or (Decrease) in creditors
Net cash provided by operating activities
Statement of cash flows
Net cash provided by operating activities as above
Cash flows from investing activities:
Dividends and interest from investments
Sales less purchases of investments plus fees
Increase in cash
Bank and deposit balances at start of year
Bank and deposit balances at end of year
Held as follows
Evelyn Partners deposit
COIF Charities Deposit Fund
PayPal balance
Bank balance
2023
2022
£
£
2,859
(60,462)
14,993
95,411
52,454
45,607
3,371
(3,507)
472
(200)
136
(2,396)
74,285
74,453
74,285
74,453
(52,454)
(45,607)
3,412
6,304
25,243
35,150
80,304
45,154
105,547
80,304
10,707
10,729
89,998
58,882
-
-
4,842
10,693
105,547
80,304

Cambridge Eye Trust

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Page 6

BALANCE SHEET As at 31 October 2023

BALANCE SHEET
As at 31 October 2023
31st October 2023
31st October 2022
Note
£
£
£
£
Investments
Listed investments per note
2
1,574,480
1,592,884
Evelyn Partners deposit
10,707
10,729
COIF Charities Deposit Fund
89,998
58,882
1,675,185
1,662,495
Current assets
Debtors and prepayments
135
3,507
Tax recoverable
178
650
PayPal balance
-
-
Bank balance
4,842
10,693
5,155
14,849
Current liabilities
Creditors and accruals
6,890
6,754
Net current assets (liabilities)
(1,735)
8,096
Net assets
1,673,450
1,670,591
Accumulated fund
Closing balance
1,672,218
1,669,359
Endowment
uOpening and closing balance
1,232
1,232
there being no movements in the year
1,673,450
1,670,591
Approved by the Trustees on 11 December 2023 and signed on their behalf by
1,670,591
1,669,359
1,232
1,670,591
Trustee

Trustee

N J C Sarkies

Cambridge Eye Trust

Printed 09/05/2024

Page 7

NOTES TO THE ACCOUNTS

1 Accounting policies

under the historical cost convention, with the exception of investments which are included at market value, to accord with the Statement of Recommended Practice :

Accounting and Reporting by Charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK (FRS102) and with the Charites Act 2011.

2 Listed investments

Listed investments
Opening market value
Sales
Purchases and accumulated dividends less equalisation receipts
Surpluses and deficits on sales in the year
Unrealised surplus arising in the year
Closing valuation
This year
Last year
1,592,884
1,694,662
(181,876)
(42,710)
178,464
36,343
6,304
(635)
(21,297)
(94,776)
1,574,480
1,592,884

These investments comprise unit and investment trusts and Charity Authorised Investment Funds.

3 Payments to trustees

No remuneration was paid for the year to trustees or to persons known to be connected with any of them.

Cambridge Eye Trust

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Page 8

Independent Examiner's Report on the Accounts

Report to the Trustees of the Cambridge Eye Trust on accounts for the year to 31st October 2023, as set out on pages 5 to 8.

As the charity's trustees you are responsible for preparing the accounts; you consider that an audit is not required for this year under section 144 of the Charities Act 2011 ("the Charities Act") and that an independent examination is needed.

It is my responsibility to:-

My examination was carried out in accordance with the General Directions given by the Charity Commission. An examination includes a review of the accounting records kept by the charity and a comparison of the accounts presented with those records. It also includes consideration of any unusual items or disclosures in the accounts and seeking explanations from the trustees concerning any such matters. The procedures undertaken do not provide all the evidence that would be required in an audit and consequently no opinion is given as to whether the accounts present a 'true and fair' view and the report is limited to those matters set out in the statement below.

In connection with my examination, no matter came to my attention:

  1. which gives me reasonable cause to believe that in any material respect the requirements to:

  2. keep accounting records in accordance with section 130 of the Charities Act; and

  3. prepare accounts which accord with the accounting records and comply with the accounting requirements of the Charities Act

have not been met; or

  1. to which, in my opinion, attention should be drawn in order to enable a proper understanding of the accounts to be reached.

Stuart Berriman (Independent Examiner) BFP FCA FCCA Chater Allan LLP 7 Quy Court, Colliers Lane Stow-cum-Quy Cambridge, CB25 9AU

Date: 9 May 2024

Cambridge Eye Trust

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Page 9

Year to 31 October 2023

INVESTMENTS Investments held at Investments held at 31 October 2022 Purchases and sales Resulting gains and losses Investments held at Investments held at 31 October 2023 Unrealised surplus
Funds and Unit Trusts Holding Book Bid Market Holding Cost or Gain or Prior This Holding Book Bid Market Prior This
value price value (proceeds) loss years year value price value years year
CG Portfolio Fund Plc Absolute Return
M distribution units 214 30,101 £136.83 29,246 214 (28,857) (1,243) (855) (389)
Continental European Income 3%
D units 11,399 18,646 £1.62 18,491 11,399 18,646 £1.67 19,068 (155) 577
Evenlode Income 2%
D income 17,225 29,921 £2.37 40,801 17,225 29,921 £2.40 41,416 10,880 615
Evenlode Global Income 1%
F Dis 24,868 29,983 £1.37 34,035 24,868 29,983 £1.39 34,485 4,052 450
Fidelity Global Dividend 3%
R income nav 20,399 36,732 £2.14 43,571 24,048 44,447 36,732 £1.01 44,758 6,839 1,187
Findlay Park American Sterling 4%
I accumulation 333 30,293 £136.00 45,318 333 30,293 £141.96 47,304 15,025 1,986
Fundsmith Equity I instl acc divs 123 7%
acc nav 6,589 25,632 £5.68 37,404 1,622 (10,304) 3,995 2,897 1,098 4,967 19,416 £6.12 30,399 8,874 2,078
Graham Macro ucits 1%
H platform 131 16,064 131 16,064 £123.59 16,165 101
Guardcap Global Equity
I Gbp income 3,183 38,100 £13.57 43,200 3,183
T Gbp income- reconstruction 1,512
T Gbp income 1,481 (15,042) 3,024 1,609 1,416 3,214 26,083 £10.12 32,517 3,491 2,944
Guinness Global Equity -2%
Z Global income 482 13,052 482 13,052 £26.51 12,780 (272)
International Public Partnerships -16%
stock 0.01p 3,840 6,155 £1.56 5,983 7,024 9,086 10,864 15,241 £1.16 12,624 (172) (2,445)
Insight Global Funds II
Libor plus B 13,987 14,732 £1.32 18,532 13,987 (19,351) 4,619 3,800 819
Invesco Physical Gold Lkd - - - 15%
unts 226 24,824 £138.01 31,190 226 24,824 £158.35 35,787 6,366 4,597
Japanese W6- Baillie Gifford -2%
Dis 1,106 19,501 £14.41 15,939 1,106 19,501 £14.06 15,552 (3,562) (387)
Link Fund - Trojan Income
X income nav 20,640 22,034 £1.23 25,401 20,640 (25,807) 3,774 3,367 406
Link Fund - Trojan Income -2%
X income nav 42,740 44,522 £0.89 38,197 42,740 44,522 £0.88 37,470 (6,325) (727)
Lyxor Core US Tips -3%
D 118 12,000 118 12,000 £99.08 11,691 - (308)
M&G UK inflation linked corporate 0%
accumulation 16,377 18,072 16,377 18,072
,
£1.10 18,049 - (23)
Marshall Wace Developed Europe Tops 0%
G nav 144 16,309 £192.83 27,776 58 (11,092) 4,563 4,590 (27) 86 9,780 £193.93 16,752 6,877 95

Cambridge Eye Trust

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Page 10

Year to 31 October 2023

|INVESTMENTS
Funds and Unit Trusts
Holding
Book
Bid
Market
Holding
Cost or
Gain or
Prior
This
Holding
Book
Bid
Market
value
price
value
(proceeds)
loss
years
year
value
price
value
Investments held at 31 October 2022
Purchases and sales
Resulting gains and losses
Investments held at 31 October 2023
Maitland MI Twentyfour AM Dynamic Bond
I income
166
18,035
£89.11
14,761
88
(8,050)
(1,536)
(1,740)
205
78
8,450
£88.62
6,878
Polar Global Healthcare Trust
3,252
10,875
ord 25p shares
708
2,373
3,960
13,248
£2.99
11,840
Redwheel Global Horizon
55
(12,719)
(131)
(210)
80
B accumulation
110
25,700
£230.75
25,279
55
(13,177)
327
(210)
537
Schroder Asian Total Return Inv Co
ord 5 p shares
6,031
30,155
£3.85
23,197
6,031
30,155
£3.89
23,461
Stewart Invrs Asia Pacific Leaders
income units
9,686
32,000
£2.98
28,882
3,545
(10,484)
(1,228)
(1,141)
(87)
6,141
20,288
£2.81
17,276
Threadneedle UK Equity income
L Dis
13,768
16,755
£1.80
24,747
13,768
(26,993)
10,238
7,992
2,246
UK Government bonds
0.25%
8,480
8,022
8,480
8,022
£0.95
8,020
Twentyfour Absolute Return Credit
83
8,031.97
A QNG
184
19,214
£94.50
17,342
266
27,246
£96.06
25,579
UK Commerial Property REIT Ltd
ord 25 p shares
24,852
21,060
£0.62
15,491
24,852
21,060
£0.53
13,072
USD Treasury Bond 7-10 year
1,872
8,094
distribution hedged
3,608
16,260
5,480
24,353
£4.17
22,841
Managed by Evelyn Partners
550,403
604,783
(3,195)
26,403
20,099
6,304
585,581
611,946
Unrealsed surplus
54,380
573,611
26,365
Charity Authorised Investment Funds
Cazenove Charity Equity Value
31-Oct
Z income units
43,020
149,524
£4.27
183,824
43,020
149,524
£4.22
181,544
Charities Property Fund
31-Oct
income units
132,076
140,000
£1.46
192,383
132,076
140,000
£1.23
162,269
COIF Charities Global Equity Income Fund
31-Oct
income units
115,510
190,000
£2.48
286,720
115,510
190,000
£2.52
291,364
M&G Charifund
31-Oct
income units- yield 6.1%
10,126
144,935
£13.91
140,797
10,126
144,935
£13.75
139,209
Sarasin Endowments Fund
6-Nov
Class A income units
161,575
150,000
£1.10
177,732
161,575
150,000
£1.13
182,580
Direct holding
Worldwide Healthcare Trust Plc
31-Oct
ord 25 p shares
200
4,992
£33.20
6,640
1,800
2,000
4,992
£2.89
5,780
Sub total for Charity Authorised
Investment funds and a direct holding
779,451
988,096
-
-
-
-
779,451
962,746
Totals
1,329,855
1,592,880
(3,195)
26,403
20,099
6,304
1,365,032
1,574,692
|**INVESTMENTS**<br>**Funds and Unit Trusts**<br>Holding<br>Book<br>Bid<br>Market<br>Holding<br>Cost or<br>Gain or<br>Prior<br>This<br>Holding<br>Book<br>Bid<br>Market<br>value<br>price<br>value<br>(proceeds)<br>loss<br>years<br>year<br>value<br>price<br>value<br>**Investments held at 31 October 2022**<br>**Purchases and sales**<br>**Resulting gains and losses**<br>**Investments held at 31 October 2023**<br>Maitland MI Twentyfour AM Dynamic Bond<br>I income<br>166<br>18,035<br>£89.11<br>14,761<br>88<br>(8,050)<br>(1,536)<br>(1,740)<br>205<br>78<br>8,450<br>£88.62<br>6,878<br>Polar Global Healthcare Trust<br>3,252<br>10,875<br>ord 25p shares<br>708<br>2,373<br>3,960<br>13,248<br>£2.99<br>11,840<br>Redwheel Global Horizon<br>55<br>(12,719)<br>(131)<br>(210)<br>80<br>B accumulation<br>110<br>25,700<br>£230.75<br>25,279<br>55<br>(13,177)<br>327<br>(210)<br>537<br>Schroder Asian Total Return Inv Co<br>ord 5 p shares<br>6,031<br>30,155<br>£3.85<br>23,197<br>6,031<br>30,155<br>£3.89<br>23,461<br>Stewart Invrs Asia Pacific Leaders<br>income units<br>9,686<br>32,000<br>£2.98<br>28,882<br>3,545<br>(10,484)<br>(1,228)<br>(1,141)<br>(87)<br>6,141<br>20,288<br>£2.81<br>17,276<br>Threadneedle UK Equity income<br>L Dis<br>13,768<br>16,755<br>£1.80<br>24,747<br>13,768<br>(26,993)<br>10,238<br>7,992<br>2,246<br>UK Government bonds<br>0.25%<br>8,480<br>8,022<br>8,480<br>8,022<br>£0.95<br>8,020<br>Twentyfour Absolute Return Credit<br>83<br>8,031.97<br>A QNG<br>184<br>19,214<br>£94.50<br>17,342<br>266<br>27,246<br>£96.06<br>25,579<br>UK Commerial Property REIT Ltd<br>ord 25 p shares<br>24,852<br>21,060<br>£0.62<br>15,491<br>24,852<br>21,060<br>£0.53<br>13,072<br>USD Treasury Bond 7-10 year<br>1,872<br>8,094<br>distribution hedged<br>3,608<br>16,260<br>5,480<br>24,353<br>£4.17<br>22,841<br>**Managed by Evelyn Partners**<br>550,403<br>604,783<br>(3,195)<br>26,403<br>20,099<br>6,304<br>585,581<br>611,946<br>**Unrealsed surplus**<br>_54,380_<br>573,611<br>_26,365_<br>**Charity Authorised Investment Funds**<br>Cazenove Charity Equity Value<br>_31-Oct_<br>Z income units<br>43,020<br>149,524<br>£4.27<br>183,824<br>43,020<br>149,524<br>£4.22<br>181,544<br>Charities Property Fund<br>_31-Oct_<br>income units<br>132,076<br>140,000<br>£1.46<br>192,383<br>132,076<br>140,000<br>£1.23<br>162,269<br>COIF Charities Global Equity Income Fund<br>_31-Oct_<br>income units<br>115,510<br>190,000<br>£2.48<br>286,720<br>115,510<br>190,000<br>£2.52<br>291,364<br>M&G Charifund<br>_31-Oct_<br>income units- yield 6.1%<br>10,126<br>144,935<br>£13.91<br>140,797<br>10,126<br>144,935<br>£13.75<br>139,209<br>Sarasin Endowments Fund<br>_6-Nov_<br>Class A income units<br>161,575<br>150,000<br>£1.10<br>177,732<br>161,575<br>150,000<br>£1.13<br>182,580<br>**Direct holding**<br>Worldwide Healthcare Trust Plc<br>_31-Oct_<br>ord 25 p shares<br>200<br>4,992<br>£33.20<br>6,640<br>1,800<br>2,000<br>4,992<br>£2.89<br>5,780<br>**Sub total for Charity Authorised**<br>**Investment funds and a direct holding**<br>779,451<br>988,096<br>-<br>-<br>-<br>-<br>779,451<br>962,746<br>**Totals**<br>1,329,855<br>1,592,880<br>(3,195)<br>26,403<br>20,099<br>6,304<br>1,365,032<br>1,574,692<br>|Prior
This
years
year
Unrealised surplus
0%
(1,534)
(38)
-11%
-
(1,407)
1%
(6,958)
264
-4%
(1,977)
(1,036)
0%
-
(2)
1%
(1,872)
205
-16%
(5,569)
(2,419)
-9%
(1,513)| |---|---|---| |||34,281
4,053
1.7%
-1%
34,300
(2,280)
-16%
52,383
(30,113)
2%
96,720
4,644
-1%
(4,138)
(1,588)
3%
27,732
4,847
-13%
1,648
(860)| ||962,746|-2.6%
208,645
(25,350)| ||1,574,692|242,926
(21,297)|

Cambridge Eye Trust

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Page 11