REGISTERED COMPANY NUMBER: 00899518 (Enoland and Waleg) REGISTEREO CHARIfY NUMBEK. 261047 REPORT OF TNE TRUSTEES AND AUDrrED FINANCIAL ￿ATEmENTs FOR THE YEAR ENDED 31 DECEMBER 20Z4 FOR LABOIIATORY ANIMALS LIMITED (A COMPANY LIMITED BY GUARArirEE) Hartley Fowler LLP statutory AuditOT5 Chartered Accauntants PavilK)n Vlew 19 New Road Brighton East Sussex BNI IEY LABORATORY ANIMALS LIMrrED coKrEKfs OF THE FINANCIAL sfATEMENTS FOR THE YEAR ENDED 31 DECEMBER 2024 Pa Report of the Trwtee• I to 7 Report of the Independ•ntAudltor• 8 to 11 stthm•nt of Flnanclal Actlvltl•s 12 nc• Sheet 13 Nots• to the AnJn¢l•l Statements 14 to 20 Detailed Statsm•rt of Fln•ncthl Actlvltl•• 21 to 22 LABORATORY ANIMALS LIMITED (REGISTERED NUMBER: 00899518) REPORT OF THE TRusfEES FOR THE YEAR ENDED 310ECEMBER 2024 The trustees who are a150 d1￿CtorS of the tharlty for the purposes of the Companies kt 2006, present their re￿ wth the finanoal statements of the charlty for the year ended 31 December 2024. The trutss have adopted provisths of kcounting and Reportjng by Charitles.. Statement of Recommended Prathtr appllcable to charitses preparing their accounts In accordance with the Financvdl Reporting Stsndard Jpplicable In the UK and Rewbllc of Irdond {FRS 102) (effectfve l January 2019). Thls rert akn wntslns the Ilrectors, reF¢)rt as requlred by company law. Labcntory Anlmals Llmlted Is a ccfflpany Ilrnlted by guarnntee and has no share capital. The cornpony was incorpjrated under the Ccfflpan￿s Act 1948. Each memter has guaranteed to pay £5 in the event of windlng up the companv. oB]E￿IvEs AND ACTIVMES ObJectl¥es and alms The Memorandurn and Articles of Association obllges the company to aP￿Y all it5 re50vrces to the advan￿r￿nt of public education in laboratory anlrnal x*nce, tethno￿ and weKare. The prindpal obJeLtlve5 01 the cornpany are to ach these alms by puPAlcalkin of the Joumal, "Laboratory Animals" ond by fundiryJ a range of initiatives In the r￿Id ol ialK*atory anlmal saence, especially focused on 'train the tralner. Inbtlatfves. LABORATORY AN114ALS LIMITED (REGIsfERED NUMBER: 00899518) REPORT OF THE TRusfEES FOR THE YEAR ENDED JI DECEMBER 2024 Slgnlficart activities The prfndpal objectives of the company have been athEved In 2024 by publithing the journal 'Lab)r4tory Animals" {LA]I, and by Con￿n￿[ng to provide financial a￿lSE￿nCe for workshops, training course5, conferences and for other Initlatlves that are relevant In the of Laboratory Anlmal Sdence, rnedicine, technoloyy and welfare. The Trustees (Council of Management, COMI held one face-ttrface meety.ng in June and a ￿rtUal TT*eUng in January.. a5 a cost savlng me3￿re it has been agreed to aim to hdd only one ra￿-t0•face meetlng annually, unless events require otherwise. The ExecutNe Committee IECI, which OVe￿ee5 the ¢ky-to-day ¢￿Tation of the company, held one laC￿tfrface meettng in December, three virtual meetlngs In February, September and Ottober. LAL'S Annual Genernl Meetin9 was held virtualty Sn september. The Edltorhl Team I￿ld six mee￿r￿S durlng 2024, one of whlch Induded Section Editors. The publlcauon frequency of the JcAwnal has condnued at 6 Issues o yeor, publlthed on-llne onty, as In*ttuted In 2021. Individual arUcle5 a￿ accessi￿e through the SAGEILAJ webste, and a '11ippable", coveT-ttr(over format such that Its layout 6nd content are Iden￿Cal to the paper k)umal, Is avalLable on the LAL weby'te. Thls Is accessIb￿ to rnembers ol Subscribing Associaty"ons who subscrite to the journal usSng a secure username and password systern. The avall6bllity of thls forrnat has the advantage of brlnglng mre trafflc to the LAL ￿EbsIte and Is also more attractNe ro advertlsers. Subscriptlon numbers In 2024 were 1,375.. 2023 totrl 1,866, 2022 total: 1,566, 2021 total.. 1,637. The Joumal continues to publlsh abstracts Sn French, Germon, Spanlsh. LAL has cOn￿nUed to fuTrJ grants In the fleld of Labwatory Animal Sdence, whlle offerirrfj a hvjh-quallty Joumal to our Subscribing A55cKhtM)n5 at a very favourable rate. The overall content and fomiat of the Joumol has remglned unchanged. The Journal accepted 79 artkle5 In 2024 Ind￿1r0 orlglnal atlcles, Revlew artlde5. Short Rep￿ts, Case Reports and Perspethve )rUcles. There were tsvo edilorlals, and four worklrrtJ party reports, these latter were., Guldance on the assessment of leamln9 outrornes lor those deslgnlng procedures and projects - Report of an Worklrwj Groupt Paln management In zebralish.. Report Irorn a FELASA WorkSng Grwp, FELASA Wothng GTOUP report.. Capture and tTrn5POrt of Ilve phalopods- recommendatlons lor sclentlllc purposes, Guidellnes for the establIshn￿t and functioning of Animal Etk*5 Committees Ilnstr(ullonal Animal Care and Use Cornmltteesl In Afrlca. The News, Notes and Cornments INNQ ￿ttIOnS contlnued to attract materkl a5 reports from SubsulblThJ Assooatlorfj on conference5, and anTh)Ur￿rnents ￿ardir¥I future conferences, events, and publkatlons. One spedal 155ue wa5 published In Cktober entitled "Bhostats￿.rs Notes.. The Tlrne to Flrst decisi￿ has fallen fram 67 to 31 day5 slnce 2021, whllst the Tlme to Flnal Dedyon lrtcreased from 47 days In 2023 to 59 day5. Tlme In producdon Increo5ed to 108 days In 2024 cornpared to 55 days In 2023 due to Issue5 In the Sa9e prCbJu￿0n w(￿ess. The five.year rc4llng Impact factor of the loumal was 2.3, an indicatyon of stable perforn￿r￿e wlth an upward trend 12018.. 1.117; 2019.. 1.495. 2020.. 2.471,. 2022.. 2.908; 2023.. 2.5). In 2023 the method of calculatlng the lrnpatt factor than9ed, whlch may affecl current and future cc¥nporfsoTLS. The Edltorial Board conslsts of five edltors, of whom are members of the Com and serve as lialson be￿een the Edilortol ￿r￿ and the Trustees, Including presentlng a rep(xt on the status of the Joufnal ar ECICOM meetsngs. The 55 5ectSon Edltors ILfjted, with a dlver5e Intemarional representsthln. LAL ha5 rnalntslned Its rc411ng yearty contract wlih the pub115her SAGE 2024. The Implicats'ons of M￿ThJ io an Open Access publishing model have £onUnued to be discussed extensivety during 2024 by the EC and Com, wlth valuable input from tre LAJ Edf(orlal Board, but the mechanlsm by which thls Ss to be achieved has yet to te finallsed. Options Include both uslng profe551oro1 publishers and thpkn.ng a sew-publishiry platforrn. Gfven that OFen Access wlll result In LAL'S maln Income stream from LAJ $th)￿rIptIOns dwlndling and needing re￿acernent ty the Introduction of an Article PrrKesgng tharye {APQ, both EC and Com 4ree that thi5 process should Th)t be rushed. LAL h￿1 a stand at the intematlonal Fneeting of Understanding Anirnal Re5earth IUAA) in May at the University of wa￿Ck. In addition, LAL spOn￿red free reglstraty'on lor up to 50 ddegates at the ExFobioteri05 Laun Amerfca 2024 meetiro in Mexro, folbwing the S￿eS￿uL sponsoring of their 2023 event. LABORATORY ANIMALS LIMITED (REGISTERED NUMBER: 00899518) REPORT OF THE TRusfEES FOR ThE YEAR ENDED 31 DECEMBER 2024 OBJECTniES AND AcrnirriES The L4L newsletter was Inltlated mid-2022 and is circulated by email to all Joumal subscrlter5 on the LAL datsbase. The New￿etter publishes the Table of Contents for the current Issue of the Joumal, with the ability to cllck through to the Joumal dlrecuy from the NeW￿etter. In 2024 over 1200 sub5crfbers recetved the Newsletter, wlth an opening rate of round 36% and a dick-through rate of 36%, which is regarded as good for this type of markeb'rrfj. The numter to the webslte was 36,023 in 2022, 47,861 In 2023 and 16,991 In 2024. wSth 387,876, 162,470 and 32,156 p&Jes vlewed, respectively, usng the Cpanel dats platform. Google Anatytics was also used In 2024, and their different rnethodology gave I0￿r figures of 7,514 web5bte vlslts and 13,519 page& It is like￿ that Google Anal￿ will be used frorn now. More data Is avallable at: https.'Inoc*erStvdio.g¢￿le,Corn1ul0Ife￿rtIngI2Id7ddq4-2bso4274-97It￿r9b27a2Sa9Is1p￿geIp_￿lI66sozcd The webslte is constantty revlewed for content and accuracy. In Ilne wlth the planned move for the Joumal to Open Access, the str￿tU￿ of the LAL webyts is undergolng a r￿e￿, whKh ￿11 contr.nue into 2025. Instibjtional support was provlded several courses and sclentific meeungs, In European countrfes as well as Argenbna, BrdzII, Indla and Srf Lanka and Mexlco. In 2024, 15 grants were awanjed from 22 appllcallons, tctallin9 49,880 Euros, compared to 14 grants from 25 application5 in 2023. Grnnts aw•rded In 2024: Numb•r purp￿ Country IndividuBII Instltutlonal Amount BA530 School for Earty Career Researchers on Sy5temaYc Reviews of Anlmal Stttdles Gold Open Access publlcatlon of Guithnce on the assessment of leaming outcome5 for thase designirvj procedure5 and projects- Report of n Worklng Group HSBLAS Sevedty Semlnars Funding open access CC.6Y pU￿1(ab.0￿ In LAJ of the FELAS4. EFAT WG report on"FELASA Worklng Group report.. Capture and trarwrt of I￿e cephalopods- recomrnendatlons for sdentlflc purposes. 18th FKAME/UoN Trolnlw Schoc4 In ExperSrnental De%'gn & sta￿stical Anal￿5 of osdence & Blomedlal Experlrnents Support for AISAL KXX Congre55 Ernpowerfng researchers & maxlmlzlng learnlng to Improve cultu￿ of Care prac￿￿5 In Sr5 Lanka SECAL Sclents'nc meeting ESLAV-ECIAM-AAWAC cOnferen￿'QUalIty In Anlmal Gire and Facility Management. Certificate course In Laboratory Anlmal Scien Attend a course Animal Experimentstion.. Welfate, Leglslation art Ethkal Committees and Evaluation of Projects ESLAV-ECLAM Summer Sch￿1 2025 Masterfs certincate (Master in Laboral¢Jry Anlmal SCIen￿ and Welfare) Second Hybrid conferen￿ on the scien￿ of Lab)ratory Anlmals in Lètln America. ExpoBioterios Ftybrid 2023 - XLKhlmllco- Mexco Tralnlng Cour￿ for tACUCs members Nonyav InstY(ution?I É3,000 BA531 BelJum Institu￿onI1 ,740 BA533 BA534 Gree Italy InStitut￿nal Insytutbonal ,000 2,740 BA536 UK Instltudcfflal 5,850 BA537 &4538 Italy Srl Lanka Institu￿Or Instr(udonal 1,200 2,99Q BA539 BA541 Spaln Institutlonal Swltsertand Institutional É4,150 4,200 BA544 BA54S India Brazll Insts"tudonal Indlwdual 5,000 É2,000 BA546 BA547 swit￿rIa￿d Instiiuiional Aryentlna Indlvidual 5,000 1.000 BA548 Mexico Institub'onal 5,(KID BA551 gentlna Institutlonal 2,000 LABORATORY ANIMALS Lllm￿ED (REGISTERED NUMBER: IJ0899518) REPORT OF THE TRusfEES FOR TNE YEAR ENDED 31 DECEMBER 2024 OBJEcfivES AND ACTIVrnES Publ1¢ Benellt statement The charltys trustees confirm that they have ccfflpled wlth the duty in secticm 1715) of the tha1￿e5 Act 2011 to have regard to the Charfty Commloorns general guldance on puNic benefit, 'Charf(les and Putlic Benefiv. The thaiitable vurposes 01 Latxsratory Anlmals we set out In its constltubon and the objects indude 'the advancement of public education in L￿b￿atOry animal suertt, techndogy weware,. The trustees ensure that the objects are achieved through the fundlng of a range of iniuauves In the field of laboratory animals and the publkat*)n of the Journal, "Laboratrry Animals" ACHIEVEMENTS A14D PERFORMANCE Charltable actlvltleg The extent of the CharitaFAe Payments made is detsled In Note 5 to the flMncW ststemen Investments undertaken by the dlrectar5 must salegLwrd the assets of the company and are In accordance v4Ith guldellne5 lald down by the charty cornmlssion. There are no 5r￿fic envlronmental or ethlcal objectNe5 tsken Into account. The Investrnenl p¢Jthlio Is Managed under an Investment Management Servlce Agreefflenr ￿th Cotstts & Co and has an 5nveSt￿nt profile for long term growth wlth medSum rfsks. Inve#rnents a￿ revlewed annually by the trustees. As part or tNs r￿eW we have consolldated cash 5avlng5 to Coutts to #reamllne management of our portfollo. FINANCIAL REVIEW ReMrve9 poIIcy The cornpony held reseNes ol £1,617,371 (2023.. £1.466,815) as at 31st tkcerrt*r 2024. The prfnclpal fundirvJ *urces of the company are the sales of the loumal and handbooks, revenue from advert15ers and Interest from Investrnents. The comp3ny has a pjllcy of holding reserve5 whlch are at least double the total resources expended In any one year 50 - The production costs of the journal could be Unde￿rttten as necessary - The cornpany's aCtfvit￿ In XI￿ort of longer-ierm charltable wolects coubj be 9JFPOrted If requlred. The dlrertors have agreed to revlew the cornpany'5 reserves pollcles on an ongolng ba51& Investment Portlollo The investment p(xifolio is managed under an Inve5trnent Management se￿Ce agreement wlth Coutts & Co. The market value ol the portfc4io as per the report frorn Coutts dated 31st December 2024 was £1,428,612 agalnsL a market value of £1,252,950 as at 31st December 2023; reallsed gains during 2024 were £49,255 {2023.' realSsed losses of E6,003} and unreallsed galns for 2024 were £99,322 (2023: £108,554). The cornpanvs results for the year and Irs flnandal posStk)n at the end cl the year are fully dlsdosed in the attached flnanckil *atements. The net Income lor the year, belore the unrealised Investment galn crf £99,32212023.' £IQ8,554) and the reali5ed investment galn of £49,25512023'. ￿alised Investment105s 01 £6,003) was a galn of £1,979 (2023.. Ioss of £17,570). The dlrettors advlse that the overall surplus for the year of £150,556 12023.. £84,981) wll Increase the general fund at the end of the year and that the balarte of É1,617,371 ￿￿11 te carried forward. Grants iotalllng £40,126 {2023'. £52,565) were made JU￿ng the year. T* Memorandum and Artlcles of A59XKation oblige5 the ujmpany to all Its resources UJ the advancement of put4ic education in laboratory anlrnal Science, technobgy and welfare. The principal oblecbve5 of the company are to achleve these alm5 by publication of the journal, 'LafxJratory Anlmals., and by fvndlng a range d InltSatives In the fleld of laboratory anlmal scknce especlally locus&J on 'traln the trainer" iniljatives. The maln Sour￿ of I￿orne continues to come from the production of the journal, the success of thls putlication has enabled the ongoing commrtrnent to the fundlng of institutional and indmdual grnnts. STRiicfuRi GOVERNANCE AND MANAGEMENT Governlng document The company 15 governed by its Nemorandurn and Artliles of A5ScKlab￿ incorpornted 2nd Narch 1967 and arrtnded 28th November 1969, 22nd June 1988, 14th lune 2004 and 25th JU￿ 2022. LABORATORY ANIMALS LIMITED {REGIsfERED NUMBER: 00899518) REPORT OF THE TRUSTEES FOR THE YEAR ENDED 31 DECEMBER 2024 STRvcfuRE, GOVERN¥V4CE AND MANAGEMENT Dirertors and M•nagtment The affalrs of the company are regulated ty its Memorandum and ￿deS cl Assoaation. A mernbEr of the company m￿t fir# be a member of a laboratory a￿M31 sclence as￿latIOn which has been aF¢Yoved by fv d1￿ctors. The comp3nWs dSre¢tors are elected by the members at an annual general meetlrvJ and Serve on the CcKbncil of managerr￿￿t (Board of Directors). As the company Is a registered charlty, these dlrector5 also seNe as charrty trustee5. They re￿1ve Information on their reskhjnslkn'lits'es from the arfvlsory materfal avallabLe frc4n the Companles House and Charity Comrnission webstes twt the company has no ￿lcY for glving formal trainiThJ to new tru5ttts. The EKecutfve Commlttee s elected by the Cwncil of Managern￿t ènd Is wponsitAe to the Counal of Managernent for the day-ttrday managerrtnt of the cornpany. The Councll d Mana9ement meet a year and the EXeCU￿Ve Comm￿tee hold forrnal ￿￿etingS or tdeconferences at ￿ast four a year. The dlrectors of the company are volunteers who are not pald for tha'r setvKe5 but are relrnbursed for travel and othtt out of pocket expen5e5. The management of the company necesytates artNitie5 which can tske a conslderatle amount of vclunteer's ￿Me, particulatly for officers and dlrectors engaged on speclfic projects. However, profes&onal ¢￿e adminlsLraUon, bookkeepSng, publishlng, advertlslng management and webgte rnaIntenan￿ and devdopment are funded on commercial ba￿5. RestM)n5bblli￿eS of Sage Publicatsons Ltd Iprevlou51y the Royal Soclety of Medidne Press Ltd) indude all aspects of prcductlon and d[strfbu￿c￿ of the journal, c(￿rdInatIOn of the edlt¢rlal process and cc41ettion of subscriptlors. The ekcUM of dlrectors from approved laboratory animal Scien￿ a￿dab0n5 someumes resuts In dlrectc¢s haviw an ntere5t in aS￿￿￿￿On5 or Instttution5 to whom grants are awarded. THIRD PARTY INDEMNITY PROVISION FOR DIREcfoRS There Is a thlrd party lThlemnlty provlslon In pla￿ for the beneni d all dlrector5 of the ctynpany. REFERENCE AND ADMINISTRATIVE DETAILS Regl•t•red Company nuffi￿r 00899518 (England and Wales) Reglstered Charlty number 261047 R•glst•r•d offlc• Pa￿lIon Vlew 19 New Road Brighton East Sussex BNI iey prtnclpal addr•ss PO Box 373 Eye Suffolk IP22 9BS LABORATORY ANIMALS LIMtrED (REGisfERED 14UMBER: 00899518) REPORT OF THE TRUSTEES FOR THE YEAR ENDED 31 DECEMBER 2024 P Rooymans B Zevnik (r￿gned 2516124) L Antunes P Jltkof N Ezov C GIItrRrt J Gregory J GuIl￿n J Helppi K ￿>P￿bee M Bernrd A Rltchle J Orellana S Wells I Blanco J L TreTh*da J B Prin5 T Buch lappolnted 2516124) P Rlederer [re￿gned 6191241 M Rltskes-Hoitlnga Ire&gned 24171241 EW￿r M Wllklnson Company Secretsry C Giltert Audltor• Hart* Fowler LLP Stslurory Aydltors Chartsed Accountsnts Pavllion Vlew 19 New Road Brlghton East Sussex BNI IEY B•nk•rs Coutts & Co 440 Strand London WC2R L srATEMENT OF TRUSTEES. RESPONSIBIUTIES The trustees (who are 41$0 the director5 of Laborntory Anlmals Llmited for the purposes of cornpary law) are reSp)n￿l￿e for wepfjrlng the Rerx)rt of the Trustees and the financlal statements in accordance wlth applicable law and United Kingdom ACCOUn￿ng Stsndards (Unrted ￿ng0￿rn Generalty Accepted Accountlng pr￿*ce) Includiro Financlol ReporlThJ Stsndard 102 The Bnanoal Reportlng Standard applScat4e In the LIK and ReputAic of Ireland" Company law requlres the tru#ees to prepare flnancw statements for each flnanclal year whKh give a true and fair view of state of affalrs of the charftsble company and of the incomlw resources and applicaoon of resources, includlng the Income and expend￿ure, cl the charitsble c￿￿panY for that period. In preparing those flnancial stater[￿ts, the trustees are requlred to sdert suitable accouMng pollde5 and then appty them conslstentty; observe the methojs and principks in Chaty SORP,. ake ludgernents ond estlmates that are reascThble and prude prepare the financial st3ternents Dn the goir¥J concem bass unless ￿ Is Inappropriate to presume that the charliable cornpany will Con￿nUe in business. LABORATORY ANIMALS LIMITED (REGIStERED NUMBER: 00899518) REPORT OF ThE TRUSTEES FOR THE YEAR ENDED 31 OECEMBER 1024 srATEMENT OFTRvsfEES' RESK*NSIBIUTIES- continued The trustees are responsib￿ for keeplng proper a￿QUAtIng recc*ds whlch thxlose with wsonable accurw at any tirne the finanaal p05ib.on of the thorltstrle cttmpary and to ena￿e them to ensure that the financlal statements compty h￿th the CompanÈs Act 2006. They are also resp￿Ible fcf safe9uardlng the assets of the chailtable company and hence for ta￿n9 rea>Jnable steps for the prevention and detecb'on of fraud and other Irregularlfje5. In so far as the truth are aware.. the￿ Is no rdevant audit informalon d whlch the charitsble companvs audf(ors are unaware. and the trustees have tsken all stsps that they oU￿t to have taken to make themsefve5 awore of ary rethnt audit Information and to establish Ihat the audIt￿5 are aware of that infomwtkffl. Th15 ￿port has ￿en wepared In accordance wlth the speclal th51on5 d Part 15 of the CompBnles Act 2006 rekityng to small companles. Approved by order of the bjard IY trustees m 22nd August 2025 and slgned ￿ its behaw bv: K AppleLYe- Trustre REPORT OF THE INDEPENDENT AUD￿oRs TO THE MEMBERS OF LABORATORY ANIMALS LIMITED (REGisfERED NUMBER: 00899518) Opinion We have the flnancial statements of Laboratory Anlmals LIM￿ (the charltable COrnpan￿ for the year ended 31 December 2024 which comprise the State[r￿rt of Flnancial Activf(ies, the Balance Sheet and notes to the financlal staternents, Indudlng a summary of slgnlfkart ￿C￿n￿ng polt1￿. The financlal reporung framework that has applied in thelr preparation is app1Kab￿ law and United Klnylom Accounting Standards {un￿ed KI￿*￿0M Genwalty AC￿pted AcC￿nting prath￿), Includlng Financkl Reportlng StsNlard 102 The hnandal Rewtiry Standard applcable in the UK and Republic of Ireland,. In our qjinlon Ihe financlal statement&. gfve a true and fair view of the stste of the charftable company's affairs as at 31 Decernber 2024 and of Its Ir￿ornIn9 reso¢Jrces and applicauon of resources, induditvJ Its Income and expentlitufe, for the year then ended. have been proper￿ prepared in accordance with Unf(ed Klngdcyn General￿ AC￿pted Accounting Practi￿, Indudlng Flnancial Reportlng Stsndard 102 The Financw Rryorbng Stsndard applicable in the UK and RepUtrA￿ ￿ Ireland,; and have been prepared in acCOrdar￿ with the requlrements of the Companies Att 2006. BJgiS tor oplnlon We COnd￿ted our audll In accordan￿ ￿th Internauonal Standards on Audltlng lu￿ IISAS IUK)13nd apF4icable kiw. Our responsbilltles under those standard5 are further deScri￿d In the Auditors, respOn￿bIl￿e5 for the audlt of the flnarKial ststements secbon of our re￿rt We are I￿ep2Thdent of the charItab￿ cornpany In accordance with the ethlc)I requirernents th)t a￿ relevant to our audlt of the linanoal ststements in the UK, IndLKling the FRC'5 Ethical standard, and we have fulnlled our other ethical re5ponsit411tle5 In accordance wlth these requlrernents. We belleve that the audit e￿de￿e ￿ have ottained is sumdent appropriate to wovtyje a bass fcff cAJr op11￿on. Concluslons r•latlnq to golng concem Ln audltlng the financlal statemcnt5, we have concluded that the trusteeg use of the gtslng cthicem bJ¥s of accountlng In the preparaUon ol the finawK*I st)tsments Is approprfaie. Based on the work we have performed, we have not identined any materfal uncertaintie5 relatlng to events or coThJIt￿ns that, Indivldualty or collectlvely, moy ca# Ignfflcant doubt on the charltable company's 4blUty to continue as a golng concern for a Ferlo(l of at least ts¥elve months from when the flnonckil slatements are authorised for1sgJe. Our respOn￿bIlItIeS and the respons1bil￿1es cl the trustees %4Ath respert to gc4ng concern ore dexrfbed In the rdevant sedons of th15 report. Other inlormatlon The trusree5 are reSpOr￿blE for the other Infcrfmètbn. The othw 1nl0rma￿0n comprlses the Informabon InclL*Jed In the Annual Report, other than the fin•nclal statements and our fle￿)rt of the Independent Audltors t￿re0￿. Our oplnlon on the flnancial ststements does not cover the other Inforniatlon and, except to the extent Oth￿Ise eypllclty Aaied In our report, we do not expre55 any form of assurance cowluslon Ihewn. In Connecti(￿ wlth (yjr èudll crf the flnanclal ststements, our responslblllty Is to read the other InforrnaJon and, In d￿ng so, consider whether the other inf0m￿tiOn Is rnatrrially inmnlstent wlth the Ilnanclal ststement5 or our kn￿￿edge Dbtalned In the audit or otherw15e appeaTS to be materlally mlsstate(J. If we Idenufy swch materlal InCon￿stenc1es or apparent rnaterlal rnis5tsternents, we are requlred to determlne whether thi5 glves rtse to a material misstatement In the financial 5taternent5 themselves. Il, based on the work we Ikive rerftymed, we conclude thal U*re Ss B materlal mls*aten*nt of thls other Informatkjn, we are required to rekWJrt that fact. We have nothing tts report in thls regard. Oplnlons on other matters pmscrfbtd by the Companles Act 2006 In our opinion, b65ed on the work undertaken In the course of the audit.. the Infomiation glven in the Repjrt of the Trustees fcf rhe financlal year for whlch the finanual statements are prepared Is conslstent wSth the finanaal staternent5,' ond the RepKJrt of the Ttuthes has been prepared in accordan￿ with appllcabte legal requlrements. REPORT OF THE INDEPENDENT AUDITORS TO THE MEMBERS OF LABORATORY ANIMALS LIMITED (REGISTERED NUMBER: 00899518) Matters on whSch we are required to report by exceptlon In the light of the knowle(SJe and urKJer*andlng of the chaiitatAe company e￿rOnn￿t obtained in the course of the a￿lit, we have nrt idenufied materfal m6sstsle￿￿nts in the RerK)ri of the Tru*e& We the nothirfj to reFort in respect ol the fdlowlng matters where the Cunpanles Act 2006 requires u5 to repjrt to you if, in our opinlon.. 6de(wate accojntlng records have nct been kept or return5 adequate for our have not been received from branches not visited ty u5,. or the flnanclal Statements are not In agreement wlth the accountiThJ records and retwns. or rtain disclosures of trustees, remunerats.on specified by law are not rnade,. or we have not receNed all the irforrnab'on and eWanaVons we requlre for our audlt; or the trustees were nol entitled to take advantage of the small companies exemrknn from the requiremert to prepare a Strateglc Report ¢x In weparlng the Repc¥t ol the Twstees. Responslbllities of tru8teeJ A5 expL3lned more fully In the Staternent of Trustees, ReskKJnslbilities the trustees {who are alg) the dlrectCfj5 of the thaiitable company for the wrp05es of company law) are resp￿&ble for the preparauon cl the finandal 5taternents and fcf belng 5atisfieil that they glve a true and fair vlvrt, and lor Such llltemal control as the trustees deterrnlne Is necessary to enable the WeparatiC￿ of financlal thternents that are free from rnaterlal mlsbtstement, whether due to fraud or error. In ￿￿parIng the nnanclal statements, the trustee5 Jre respjndble for assessing the Charr(ab￿ company's abllty to continue as a gcing concem, dlsd051ng, 05 appllcaL4e, matters related to g&ng concem and uslng the going concern ba￿S of accounung unkss the trustees elther Intend to114uldaie the thorftstsle company or to cease operallons, or have no realistt alternotwe but lo do so. REPORT OFTHE INDEPENDENT AUDrn)RSTOTHE MEMBERS OF LABORATORY ANIMALS LIMThED (REGIsfERED NUMBER: 00899518) Our responslbilltles for the audit of the financlal gtJtements Our objeckn.ves are to obtaln rea￿nats1e 8S9jran￿ aix)ut Whett￿r tkK financlal statements as a whole are free frorn material misstatemert, whether due to frnud error, and to Issue a Report d the Independent Audtor5 that Indudes our otynion. Reagjnable aSSurar￿e Is a Ngh levd of assurance, Is not a guarantee that an audli cc¥¥Jucted In accordan￿ with IS4s IUV will always detect a material misstatement when it exists. Misstatements can arise from fra or eThor and are consldered Material if, lndNidu61￿ or In the aggregate. they coubj reasonabty ￿ expected to Influence the ea)nomic decision5 of users taken on the basTs ol these financial ststemen Audit approach to idertifying and a95egslng Prt¢fttial risk5 related to irregularities Our pr(xedwes for Idenufying and a55e5slng risks of material misstaternent in resFett of irregLlarib'es, inc1￿11￿j fraud and nOn￿MplIanCe wlth laws and regulatbons, Snduded the following.. Enqulrfrbj ￿ mènagement, Includlng oLkninlng and revlewlng wpp)rtlng dc(umertatlon,corKemlng the (￿MpanyS ptsllde5 and procedure5 relaung to: dentfyir¥J* evalua￿ng and ccrfnptylng With laws aTrJ regulaUon5 and whether they were oware d any Instances cl non-cornp1ian￿., - cktectlng and re5kKJndlw to the rlsks of fraud and whether they hwe knowledge of arry actual, suspected or alleged fraud,. and - the Sntemal controls establlshed to rnldgate rlsks related to fraud or nonforn￿rdr￿t laws and regulalons. - DISCUS￿￿￿ amcry the enga9emnt team regardlng how and ¥kne fraud rnlght ¢XCUT In the flnancljl 5tsternents and any potenUal Indlcators of fraud. Obts5nlw an understandlng of the legal and regulatory frameworks that the company operates In, focuyng on those laws and regulatlons that had a direct effett on the flnanclal statemerts or thal had a fundamental effert on the operatlons of the company. The key ￿wS and regulations we eC￿￿dere1 to have a dlrect effect on the financial statements Included the Finanaal Rep)rtlng Standard FRS 102 'Tre Flnanclal Reportlng appllcable In the UK aTh1 Repu￿1¢ of Ireland., char[￿e5 SORP IFRS 1021 'Accounts'ng and Reporting by Charities.. Ststemenl of Recornmended Practke and the Companies Act 2(K16 and we a55e5sed the extent of complIa￿e wth these laws and regulatlons as part cl our procedures on the reLry￿d finanoal statement btems. The key laws and regulation5 we conthlwed to have h&a a fundamental effect ￿ the operadons of the company was the Chartries Art 2011. Audlt approach In ruponse to IdentKled rll Our procedures to re5p)nd to tlsks léentlfled Int￿ded the following.. Inqulrlng of rnan￿ement and, where approprfate, those char9ed with g0veman￿, as to whether the entlty 15 In complIan￿ wf(h 5uth law5 and regulauons. - Inwung cc*respoThJence, 11 anyi wlth the relevant I￿en￿r￿j crf regulatory authorftle5. - Revthlng the flnandal staternent dlsdosures and ￿ to 5UPWtlng documentaUon to assess cornpllan￿ ￿th reporung requirernents. Rev*wlng meetlng mlntrtes where avalhble for any Indlcatlon of non