## **Registration No. 233838** 

**SIR JULES THORN CHARITABLE TRUST FINANCIAL STATEMENTS FOR THE YEAR ENDED 31 DECEMBER 2024** 



THE SIR JULES THORN CHARITABLE TRusr
REPORT OF THE TRusfEES
ST
FOR THE YEAR ENDED 31 DECEMBER 2024
Charlty Number
233838
Re8iStered Off•ce
24 Manchester Square. London. WIU 3TH
Trustees
Elizabeth Charal (Chairman)
Timothy Harw-samuel
Julian Ide
Mark Lever OBE
Prof Sharon Peacock CBE Fmedsci
John Rhode5 Ire5iEned 31° December 20241
Prof David Ru￿e1￿j0neS MBBS, BSC. MD, FRCP
William Sporborg
Ben Dulieu (appointed 31 March 2025)
Dirert
Rkhard Benson
Auditor
Haysmac LLP
10 Queen Si p￿Ce
London
EC4R JAG
Bankers
Natwest
250 Bishopsgate
London
EC2M 4A4
Solicitors
Mills & Reeve
Botanic House
l(Kl Hills Road
Cambridge
C82 IPH
Investment M•na8ers
Ruffer LLP
80 Victoria
Street
London
SWIE 5JL
Van8uard Investments UK Ltd
4th Floor, The Walbrook 8uilding
Lontlon
EC4N 8AF
8alllie Gifford & Co Ltd
Calton square
l Greenside Row
Edinburgh
EHI 3AN
BlackRock Investment Management IUKI Ltd
12 Throgmorton Avenue
London
EC2N 2DL
Sarasin & Partnets LLP
Juxon House
St Paufs Churthyard
London
EC4M 8BU
Troy Asset Management Ltd
33 Davis Street
London
WIK 4BP

THE SIR JULES THORN CHARITABLE TRUST
REPORT OF THE TRUSTEES
FOR THE YEAR ENDED 31 DECEMBER 2024
The Trustees present their report along with the audited financial ststements of the charity forthe year
ended 31" December 2024.
The finanual statements have been prepared in accordance with the charivs Trust Deed, the Charitie5 Art
2011. and the Statement of Recommended Pr¥t1￿ for Charrties {SORP 2019). accountlng policies are
set out on pages 19 to 21 of this report.
The report describes the Trust's governance and management structure, its grant programmes, and main
activities for 2024. The Board of Tmstees completed a review of the Trust's strategy at the end of 2021 and
implemented a number of chan8es to our grant pro8rammes fwom 2022. The Trustees have continued to
refine the grant programmes, infomied by advice from the Tiusys Medical Advsory Committee, feedback
from current and previous grant-hoklers and other eviden￿ about future needs and pr￿rItieS for the
research and health and care seciors.
erall, however, the Trustee5' assessment is that the Trust's grant pro8rammes worked well durin8 the
year. and the volume and hwdh quality of applications indicate that each programme is addressing an
important area of need.
The contlnued P￿$S￿re$ on hea￿h and care services ènd the diffKult economlc climate nevertheless mean
that many of the organisatlons that the Trust supports have continued to fate a period of uncertainty and
increasin8 demand for their services. The Trustees will keep the position under review and ensure that the
Trust's actfvities continue to respond to changes in the external environment, supw)rt the TfUSt's tharitable
objectives and remain sustalnable forthe long-terni.
str￿ture, Governance and Marbagement
The Sir Jules Thom Charitable Trust is constituted under a Trust Deed dated 18th February 1964 and is a
registered charity, number 233838. It was estabI￿hed with an endowment from Sir Jules Thom. The Trust
does not fundraise and seeks to continue the charitable work inspired by Sir Jules through the careful
stewardship of our existin8 resources. The charity has no fundraising actNfties requiring disclosure under
S162A of the Charitles Act 2011.
The Trust Is governed by a Board ofTrustees who ovetsee the Trnsvs governance. set the strategic
direction. and revlew the Pro8￿55 of its implementat*Jn. The Trustees normalty meet twice each year and
are able to deal with all essential business between meetings through corresp)ndence and online
conferencing.
The Investments Sub-Commr(tee advi5e5 the Board on the Trusvs Investment strategy and assesse5 the
performance of its Investments. The Sub-committee held two meetin8s during the year and makes a report
to the Board following each meeting.
The Tnjstees wish to exp￿55 thelr heartfelt thanks to John Rhodes. who retired from the Board In
December 2024. They are grateful for his k)n8-Standin8 contribution to the work of the Trust. as a Trustee
and member ofthe Sub-committee.
The Board 15 also supported by the Tntst's MedKal Advisory Q>mmittee {MACI of leading clinicians and
researchers, which oversees the peer review of research grant applications and makes recommendatlons to
the Board on funding. The Committee held three meetin85 in 2024. The Trustees wish io express their
enormous gratitude to Prof Stuart Forbe5 and Prof Heidi Johansen-8er& who stood down from the
Committee when their tem)s came to an end in December.

THE SIR JULES THORN CHARITABLE TRUST
REPORT OF THE TRUSTEES
FOR THE YEAR ENDED 31" DECEMBER 2024
The Board undertakes an annual revlew of its effectiveness. in order to ensure continued compliance with
the Charity Governante Code and relevant good practice. The review in November 2024 took account of
further regulatory changes that came into force as a resutt of the Charities Act 2022. and new or updated
8uidance putrAished by the Commission.
While the Trust Deed does not provide for a minimum or maximum number of Trustees, the Board's Terms
of fteferen￿ state that there will normalty be not less than seven and no more than ten Trustees. The
composttion of the Board is kept under review to ensure Its members continue to provide the range of skil
required to support the Trusys strategy. The Board has considered guidance published in the Code
regarding the period for which individuals should normally seNe on Ix)ards and new Trustees are apkx)Inted
for a temi of 5 years. which may be renewable with the agreement of the Board.
When Trustee vacancies arise, indNiduals are identif*d who provide the ￿quired skills and the broader
reqU1￿ments set out in the Trustee Role Description agreed by the Board. The vacanLy that arose at the
end of 2024 was publicly advertised. ShOrtl￿ted candhjates are invited to a Se￿ction interview, which may
lead to an appointment to the Board. New Twstees are gNen a briefing atrx)ut the Trust and all aspects of
their responsibilities, including governan￿. Trustees are also offered the opportunity to attend sector
specific courses run by the AssotiatK)n of Medical Research Charities IAMRCI and other provider5 and in
addition are made aware of chan8es lo Charity Commission guidance as and when appropriate to their role
on the Board. Where appropriate. Inductlon meetings With the Trust's wofessK)nal advisors are also
offered. All Trustees are unpaid.
The Trust has a Conflicts of Interest Policy, which sets out the principles which are applied to identify
transactions and decisions in which individuals may have a personal interest, and the process for managing
potential conflicts. The Policy applies to all Trustees. Trust staff and members of the Medical Advisory
Committee.
The Trust operates with a small team of four staff. inthding the Director. who provldes the key
managernent role within the definition of FRS 102. The Director is attountable to the Trustees for the
implementation of the strategy a8reed ￿ the Board, and for the da¥-to￿a¥ management of the Trust.
The Trust acknowledges the importance of its staff in ensurin8 both the on8oin8 Strate8ic development and
efficlent administration of the charity. The overall aim of the Trust's policy Is to offer fair pay to attract and
retain appropriately qualIf￿d staff to lead, manage and administer the charity and to fulfil the charitable
objects on behalf of the Trustees. The Trustees review the reMUneral￿n of the Dirertor and other staff on
an annual basis, after benthmarking to market conditions and other slmilar tharities.
Risk Management
The Truslees are responsible for monitoring the risks facing the Trust and ensuring that risks are managed
effectwely. The Trust has a fornial risk register which is regular￿ reviewed by the Board, and risk is inherent
to the Board's discussions on all aspects of the Trust's work. In addition, the Board considers any
recommendations from the Twst's auditors regarding further improvements to the Trust's system of
internal controls, and management responses to recommendations. The Investment Sub-committee
reviews risks specifically refated to the Tru5Ys investments.
The principal risk5 facing the Trust are-
Hnanclal- where inappropriate asset alkxation or adverse rnarket conditions could potential
undemiine the finantial sustainabilty of the Trust or mean that totsl returns from the Trusfs

THE SIR JULES THORN CHARITABLE TRUST
REPORT OF THE TRUSTEES
FOR THE YEAR ENDED 315T DECEMBER 2024
investments were not Su￿lent to meet rts nornial level of grant commitments.
The Trustees kx)k to addre55 this risk through perm￿liC review5 of the investment strategy. and the
ongoing assessment of irwestment perfomiance by the Investments Sub-committee. The risk of short-
temi volatility in investment returns ￿ further mitigated by the Trustees. policy of maintainin8 5uffKient
cash balances to cover near-tern) grant commitments. The Board carefully conslders the affordability of
new g￿nt commitments when setling the annual budget.
Strategic- where the Trusvs grant making strate8y must keep pace with deveknpments In research.
cllnical practice and relevant sedors of care.
The Trustees continue to refine the Trusvs grant programmes. When making s4gnificant awards the
Trustee5 consider advice from the Medical Aifvisory Committee and external experts contributing to the
peer revtew of ￿Search proposals. The criteria forthe health and care programmes were reviewed
during 2024, and the Chaimian and Director visit all the organ￿atIonS shortlisted under the Trust's
capital grant programme for heaRh and care projects.
Operatlono1- where processing failures, fraud. or major inodents. would impede the charrvs abilr(y to
function effectivety. and thus to delNer its charitable objectrles.
Internal controls are kept under review, and systems and processes were further devebped and
documented during 2024 to enhance integration and efficiency.
Compliance-where a failure to compty with charity law, the general law. or the founding Trust Deed.
would compromise the charit￿$ status and remrtat￿n.
The Trustees revtew 8overnance arrangements on an annual basis and wlll conduct a fvrther review of
the Board's effectiveness later in 2025 to ensure continued compliance.
In common with other organi5ations. the Trust's r￿k management arrangements have been tested in
recent years through the pandemio ihe subsequent pericd of economic uncertainty and. more ￿entty, bv
volatility in financsal markets in the Spring of 2025. The Trust does not face the same challenges as charities
whlch are dependent on fundraisin8 or or8anisation5 delivering front-llne services. The Trust's ability to
navigate the changes in the external environment since 2020 has nevertheless confimed the Tnjstees,
previous assessment of the principal risks facin8 the Trust and that its risk assessment process 15 robust.
Overall, the Trustees are sattsfied that all risks are betng managed effettNely and that measures are In
place to ensure good govemance. prevent financial or adrninistratNe fraud or malpractice, protect the good
reputation of the Trust, and ensure comFdiance with relevant leg'islatK)n and 8ubdance.
The Trust Deed gives the Trustees absolute discretion to appfy the capital and income of the Trust for
general charitable purposes but, in doing so, they take note of the Founderfs wishes. In keepin8 Wlth Sir
Jules's original Intentions. the Trust's largesl gran1$ 5UPPOrt translational medical research undertaken in
the UK'S leading medical schoo15 and NHS organisat¥)ns. Beyond medical research, the Trust a150 SUPPOrts
projects to Integrate and improve care for people living with physlcal or mental ill health and provides help
with core costs to smaller charities providing practical and emotional support to people lfving with ill health
or disobility. and to their families and carers.
In dlschar8ing their reswnsibilitles. the Trustees confimi that they have due regard to the Charity
Commission's published guidance on the Public Benefrt requirement under the Charities Act 2011.
In pursuit of Its objectives, the Trust delNers publbc benefit by providing awards to universitles, NHS
organisations and other reg￿tered charities in the UL Awards are nornially m•Je through the Trust's

THE SIR JULES THORN CHARITABLE TRUST
REPORT OF THE TRUSTEES
FOR THE YEAR ENDED 31" DECEMBER 2024
competitive grant programmes: the detaib of which are available on our website.
The Trust did noi directty advertise Its research pn)8rammes during the year but wrote to the Heads of all
UK medical schools inviting applications for the Sir Jules Thorn Award. Information about both the Award
and Research Infrastructure Fund has been published in Research Fortnight. The Trust placed an
announcement at¥)ut the Innovation and Improvement in Health and Care Fund in CNII Society to ralse
awareness of our programmes and ensure that we continue to attratt the strongest p)ssible T￿Id of
applications. Across our grant programmes, the Trust continued to receive significantly more appllcations
than it is able to fund. The quality of applications. particularly for larger awards. remalns high.
Further infomiation about the operation of ourgrant programmes in 2024 is set out below.
The Sir Jdes Thom Award for Bl￿edka1 Resea
The Sir Jules Thorn Award supports the work of outstanding investi8ators who are in the early stages of an
establlshed clinical research career. tt offers a grant of up to £1.7million over 5 yeats. Since the inception of
the Award in 2(Kll, the Trust has pledged almost £27m to fund the highest quality translational research
which seeks to bring benefit to patients through improved diagn￿tiCS and/or the devek)pment of new
therapies for important clinical problems. Research can be in any f*ld of clinical research, and in recent
years we have funded major research projects in areas as dTverse a5 developin8 tools to measure and
predict the trajectories of severe mental illness, the development of stratified theraples for HCC liver
cancer, and novel diagnostk and therapeutic insehts forfibromyal8ia.
The Award is made following an annual competition among UK medical schools and NHS organisatior￿.
Applications a￿ subjected to ri8orou5 peer review by the Medical Advtsory Committee and external experts
in the relevant clintcal r￿Id. The Trusys peer review process is ac(￿dited by the AMRC and complies fullv
wr¢h the Association's six principles of peer review-. proportK)nality, independence, diversity, rotstion,
impartlality. and transparencv.
The terms of the Award stipulate that intellectual property rfghts created as a result of Tnjst-funded
research should be protected and exploited where commercialty worthwhile. An Intellertual Property
Agreement with each inslitution defines issues of proteCt￿n and explottation. and the arrangements for
sharing any commercial income which is generated. The Trusys share of any such intome would be
allocated to the Trusys charitable purkx)ses.
Research Inlrastrurture Fund
The Trust has a long track record of supporting capital investment in research equipment and facilitie5. The
Research Infrastructure Fund 5UPPOrts capital investment that will accelerate intemationally compethive
research in UK universtlies and NHS organisations. Applications may address any discipline or disease area
but must demonstrate that the investment will translate into improvements in healthcare for patients.
The programme is open to UK universrEre5 and NHS organisations. Applications are also accepted from UK
registered charities wh￿h work in partnership with unrversities and the NHS to support translational
researth. Short-listed applKations are subject to external peer review.
Innovation and Improvement in Health and Care Fund
This Fund is open to registered chartiies in the UK and to NHS organtsations. Applications are also accepted
from UK unwersities that work in partnership with charities or the NHS to 5UPPQrt innovation and
Improvements in heatth and care.

THE SIR JULES THORN CHARITABLE TRUST
REPORT OF THE TRUSTEES
FOR THE YEAR ENDED 315TDECEMBER 2024
The programme is desl8ned to SUPPOrt the devebpment of new models of care and the integration of
health and care servites. As noted above, the Trust kK)ks to SUPPOrt projects whth are either scalable or
replicable by other or8anlsations and therefore have the w)tential to deliver benefits Lyond a single
setting.
The programme aims to support NHS organisat¥)ns and care charities to respond to the increasin8 pressure
on services. and to improve oulcomes for their benefiaaries. The fund was re-launched in current form
in 2022 and in its first year recepied four times the number of applications as the previous scheme.
Applicatlons grew by a further 40% in 2023. This scale of growth indicates that the Fund is responding to an
important and 8rowing need, but the Trust is also very cons(￿u$ of the workk)ad for organisatlons applySng
for fundin8. For the 2024 funding round. the TNst therefore sought to engage with potential applitants
before they invested lime and resources in submittin8 a full application. This process was well-receNed and
reduced approximately 120 initial expreSS￿nS of interest to 62 fornial applications.
The Ann Rylands Small Donations Pro8r*nme
The programme is named In honour of a fornier Chalrn)an of the Trust land daughter of Sir Julesl and
awards 8rants to SUPPOrt the core costs of small charities IwhKh for the purposes of the programme are
defined as those with an annual Income below £2ml. Charities can app￿ for grants of up to £5,0(Kl.
The funding crlteria were further refined during 2024 to enable the Trust to Increase sUPPOrt for smaller
charities whose work aligns wfth its mission to improve prOv￿10n in health and care. The Trust prioritises
applications from charities providing Prnctical and emOt￿nal support to people INing with physical or
mental ill health. living with disabilit￿s. people needing palliative or end-of-lrfe ca￿. and their families and
carers. Although the level of individual awards is modest, the cumulative support that the Trust provides for
smaller charities is SiEnrficant and feedbatk from recipients Ind￿ateS that the programme is valued and
continues to meet a need. This is refiected both in the continued volume of submissions, and ty the
financial and operatin8 pressures that many smaller Charit￿5 report in their applications.
The Trust received 564 applKations from Small charities In 2024, compared to 516 In the prevbous year.
During the first quarter of 2025, the volume of applicalK)ns reduced to 133 from 194 in the same perlod the
prevlous year. reflerting the changes made during the course of 2024 to refine and clarify the criteria, and
further work to streamline the application and assessment processes. The funding environment and level of
demand for services nevertheless remain very challenging for many small charities. and this will continue to
be ￿flected In the volume of applications.
During 2024 664 grant applications We￿ prlxessed. and 159 new awards and 2 extensions were made by
the Trustees totalling £3,124,154, including future year commitments. Thls was 7% lower than the
£3,367,999 awarded In 2023. The largest factor in ihis reduction wa5 an underspend of approximatety
£106K for the Ann Rylands pro8ramme in 2024. The programme was closed for 6 weeks overthe summer
to refine the criteria and darify the guidance on the Trust website in reswnse to a high volume of un-
fundable applications. The Trust also received a high volume of applications at the end of the year. meanlng
that some awards were carried over to the start of 2025.
Alongside the new awards made in 2024. the Trustees also agreed duri￿ the year to rescind three P￿VIouS
awards..
two capltsl grants totalling £220.th)J. rnade in 2019 2021. where the grant-holders had been unable
to progress the project
£560,325 for a prev￿￿5 research project where the Principal Investigator left the institution holdin8 the

THE SIR JULES THORN CHARITABLE TRLIST
REPORT OF THE TRUSTEES
FOR THE YEAR ENDED 31ST DECEMBER 2024
award, and the university was able to identfy alternative funding to complete the wor
Another research award was succe5sful￿ completed during the year, with a small underspend of £185
against the original award. A total of £780.510 has therefore been wrbtten bacl and the level of grant
Èxpenditure shown in the accounts reflects the net figure afterthis sum has been deducted from the value
of new awards.
The number of applications to the TrusY$ grant programmes increased by jvst Ljnder 5% in 20241664
applications against 634 in 20231.
A full list of grants can be found on pages 30 to 34 of this rewrt. and highlthts are summarised In the
followin8 table.

THE SIR JULES THORN CHARITABLE TRUST
RE14)RT OF THE TRUSTEES
FOR THE YEAR ENDED 315T DECEMBER 2024
M￿m￿oI ne4V In 2024
Applications
Recelved
Grnnts Awaided
TOTAL Funds
Pledged In Year
159
2022.. 221
£3,124,154
2023.-
£3.367,999
2023.. 634
Applications
Received
16
Full applications Invited
Appllcatlon$
Shortllsted
£1.695.757 awarded to the University of Oxford for their project:
Instability Measurement to Predict and Alter ainical Trajectories of Severe Mentsl Illness (ImPA￿-SmIl
2023.- 13 opplkotions were received. As this year. 5 of those were invited to submitfullopplicotions and three
shortli5ted condidotes invited to inteThiew.
An extension of £19,801 was abo approved for a previous Award held by the Unlversity of Bimiingham.
A further £14,546 was approved to extend a studentship at UCL awarded under the Trust's previous PhD
programme.
Capital Awards
Applications
Received
62
Applications
Shortllsted
Awards for Innov•ti¢)n and Impro¥Ynent In Health afbd Care
22
Awards for Research Infrastrnrture
£I.I#)O.IX¥l awarded in 2024
£535,￿￿1 for 2 projects SUPPOrtin8 the development of innovative care modeLs
£465,CKKI for 2 projects supporting research infrastructure
2023.. 0 totol oA105 applicotions were receivedfor the two copitol (ywordprogrommes. £l.IX)O.OCQ w¢75 UWt7rded
to 4 projects supporting either innovotions in core or investment in research infrastructure
The Ann A0￿d$ Small DoD•tlons Prtwamme
Applications
Recelved
564
Awards
Granted
154
£394,050 awarded in 2024
to small charities across the UK providin8 practical and emotional support
to people with-or at high risk of - phy5ital OT mental ill health. people
INing with disabilty, and their families and carets.
2023.. 0 total of $16 opplicotions were received. and 213 (Iwords were made with G tot¢71 value of £539,050

THE SIR JULES THORN CHARITABLE TRusr
REPORT OF THE TRUSTEES
FOR THE YEAR ENDED 31" DECEMBER 2024
Plans for the Future
As outlined above, each of the TrusY5 programmes received S￿nIfiCant1V more applK*ions in 2024 than it
was able to fund, and the quality of applications for larger awanls remained hvah.
The Trustees have revrewed the outcorne of the comWition5 for each pro8ramme and agreed some
further refinements to the award criteria and supporting processes for 2025 to ensure that we continue to
attract Innovative and impactful projec15 whilst ensurin8 that the workload for applicants and the Trusys
team remains proportionate to the number of awards. The Trustees will keep the programmes under
review to ensure that the Trust continues to focus its funding in a￿a$ where we can make the greatest
dlfference.
The Trustees consider that the Trust has adequate funds to meet its current obligatM)ns and to finance its
planned activities.
Financial Review
The endowment provided by Sir Jules Thom remains the source of funding for the Trust's grant-making
activities and our day-to-day operations.
As explained below, the Trust operates a total return approach whKh enables a prudent amount of
investment gains made in previous years to used to augment distributions. The Trust i% therefore not
solely reliant on the level of our imiestrnent income in determining how much it 15 able to distribute in any
one year.
In 2024. we re￿1Ved income of £2,110.401 from the Trust's investments. Thi5 r￿Ure included £1,717,675
from the investment wrtfolios managed by Baillie GrfFord, Sarasin, Ruffer and Vanguard l£1.577.504 in
20231. The balance of £392,726 was derived from Interest on cash deposlts1£429.947 In 20231 held with
Investe¢ Bank and Natwest.
The modest reduction in Income from cash deposits reflects m¢)vements in interest rates, and the Trustees,
deci5i0n during the year to place more of the Trust's cash balances in BlackRock'5 Sterling Government
Llquidity Fund (which is an UA-rated money market fund investing in Government bonds and other
Instrurnentsl. The fund provide5 greater fiexibility than fixed-term bank deposit5 while minimizing the risk
to capital. Returns are re-invested in the fund and are therefore not shown as Income in the accounts.
The Trust placed £5.5rn in the BlackR¢xk fvnd towards the end of 2023, and the balance at the end of that
year was E5.521,923. The balance on 31. December 2024 wa5 £9,370,711. Thi5 increase was mirrored by a
reduttion In the cash balances hekl in interest-bearing deposits with Natwest and Investec Bank (which
reduced from £10.679,590 at the end of 2023. to £7.612,531 on 31° December 20241.
The Trust's total expenditure in 2024 was £2,821.290. which induded net grants of £2,343.644 and
investment managers, fees of £42,180. resulting in an operating defiat of £710,889. This was off-set by net
Investment gains of E8.655.915, resutting in a net positive movement in funds of £7.945,026. for the year
(compared to £3,527,704 in 20231. This improvement is welcome and showed that the value of the Trust's
endowment tontinued to recover following a signifTrnt loss in 2022. Maintaining the real-terni value of the
endowment is essentTral to ensure that the Trust can continue to maintsin its charltable expenditure over
the long-temi.
The total value of funds hekl by the Trust on 31st December 2024 was £119,853.93412023 £111,908,9)81.
Details of transfers between general and endowment funds are detailed below.

THE SIR JULES THORN CHARITABLE TRUST
REPORT OF THE TRUSTEES
FOR THE YEAR ENDED 31 DECEMBER 2024
Reserves Pollry
Under the temis of the Trust Deed, the Endowment Fund is expendable at the Trustees. dlstteth)n and
provldes the resourc￿ to finance the Trust's activities. includin8 its administrat￿n. The Trustees,
intention is that the Trust's grant-making should continue for the foreseeable future and the investments in
the Fund are therefore rnanaged on a k)n*tem) basis. as described beknw.
The Trustees aim to have a sustainable distrit￿lOn policy which maintains the level of charitsble givin&
provided it is prudent to do so. They have adopted a total retum approach. Investment income is therefore
reinvested Sn the Fund. and expenditure is financed by cash wtthdrawn according to a fomiula which is
intended to maintèin the long-temi value of the fund while allowin8 a proportion of investment gains to be
distributed as grants. The current fomula provides for up to 3.5% of the market value of the Fund,
averaged over the prevtOUS three years. to be withdrawn. subiett to the value of the Fund remainin8 above
minimum level.
In 2024, the Tnjstees have authtirised an addith)nal transferfrom endowment funds to cover the shortfall
in unrestricted funds needed to finance the grants awarded in the year. This ts presented as a transfer
between funds of £668,708 in the Ststement of Flnancial ActNities.
The Trust does need to retaln unrestricted income fvnds as reseThes although in some years such funds
can remain due to the timing of tommrtments. There were no such balances extant at 31 December 2024.
At the year end the value of the Endowment Fund was £119.853.934 whith the Trustees consider adequate
In the contexl of the above policy.
Investment Policy
The Trust Deed does not impose any restrKtion on the Trustees, power to invest. The endowment funds are
invested for the lon8 term wtth the professional guidance of the Trusvs investment managers, who operate
with discretionary mandates but Subject to guidelines defined in the Trust's Investment Policy.
The Trustees last undertook a formal review of the Investment Policy during 2020. This included an external
assessment of asset allocatK)n and historic performance and a re-tendering pro￿55 to a￿e$S alternative
approaches and test managers, perfomiance and value for money. The recommendations from the review
were approved by the Trustees and fully implemented in the Sprlng of 2021.
The effect of the changes was to increase the woportion of the Trusys hJn8-term investments held in
equitles to approximately 70%. Thi5 is the level that the Trustees conslder ne￿$sary to achleve the Trusvs
investment objective of achieving retums of 3.5% above the Consumer Prices Index ICPII. net of fees.
measured over a rollin8 3-year period. While 8￿ater exposu￿ to equities carries the risk of volatility In the
short-term, the Trustees consider thi5 to be balanced by the Trust's other more defensive investments and
strong cash balances.
The retums achieved durin8 2024 by the Trnsys investment managers were: Sara51n (which holds the
Trust's funds in a pooled fund. comprising approximatety 70% equitie5110.%: Ruffer la more defensive
fund with approximatety 15% equitiesl-l.O%, Baillie Gifford IllTh equities) 9.6%, and Van8uard11(MYA
equitiesl 16.0%. Overall. the perfomiance of the funds managed by Sarasin and Vanguard was satisfactory
given market conditions. The 12-month perfomiance of the Baillie Grfford fund was also Satisfactory In
2024, tKrt the fund has still to recover from the very significant losses incurred during 2022 and remains
Substantially below it5 original value. The Investments Sub-committee continued to moniior the Baillie
10

THE SIR JULES THORN CHARITABLE TRUST
REPORT OF THE TRUSTEES
FOR THE YEAR ENDED 31ST DECEMBER 2024
Grfford Fund closefy throughout the year and met with Baillie Gifford to discuss perfomiance and the
changes that the firm has made to the man4ement of the Fund. The Sub-committee will continue to
assess perfom)ance in the months ahead.
The performan￿ of the fund managed by Ruffer ￿Mained disappointing. Folbwing 8 tender process, the
Board agreed In October 2024 to trdnsfer the funds managed by Rufferto a Mu￿1-aSSet fund mana8ed by
Troy Asset Management Ltd. Th￿ process was completed in February 2025.
As with the Trust's other managers, the Board considered Tro¢s approach to Environmental, Social and
Governance IESGI issue5 as part of the tender process. The Trustees expect all the investment managers lo
adopt an active policy on the exercise of voting rights in accordance with the principles of good corporate
governance published by the InstitUt￿nal Shareholders, Cornmittee. ESG considerations are included in the
managers. report5 to the Trustees.
The Investment manager5 provide valuations and perfomante report5 to the Investments Sub-commrttee
on a monthly basis, and the Sub-committee meets each mana8er at least once per annum to review the
performance ofthe funds which they manage.
The Trustees are conscious of the need to focus on the long-term performance of the endowment,
longside this ongoing monitoring of the perfom)ance delivereil by indr¥Klual managets. The Board
discussed data on long-temi performance at its meeting in November 2024 and has tommissioned external
support to undertake further analys￿. The OLrtputs of this exercise will inform further consideration of the
most appropriate asset allocation - between cash and different fomis of k)ng-term investments- to ensure
the future sustainabllity of the Trust, and to deliverthe retums required to support our grant programmes.
The Trust's cash resources- £7.612,531 at the year*nd- are Invested to ensu￿ that funds are readily
available to meet grant payments and other obli8ations as they fall due. Alongside these cash balances, as
noted above. the Trust also held £9.370.711 at the year*nd in BlackRock's Sterling Govemment Liquidity
Fund. The BlackRock Fund is highly liquid. meaning that the Trust can recall cash at 24- to 4&hours' notice.
if required to meet grant payments or other obligations.
The Trnst therefore held a total of £16,983,242 in cash and short-tem) investments, which was equNalent
to 93% of all outstanding 8ranl commitments. The Trustees considered this to be appropriate, when
coupled wlth the Trusvs substantlal £119.8m of expendable endowment funds.
The Trustees consSder that their reswinsibility for the safety and perforn)ance of the Trust's investments Is
discharged appropriately by the arrangements set above, when combined with the Trust's own
monitoring of portfolio attNity. and the annual audit procedure5.
Condu5ions regardirry Goir¥d Conwn
The Trustees have a reasonable expectatK)n that the charity has adequate resources to continue Its
activities for the foreseeable future. The Trustees are not aware of any material uncertainties about the
charitrfs ability to continue and accordingly, they consider it appropriate to adopt the going concern basls
in preparing the financial statements as outlined in the Statement of Trustee5' Responsibilities on page 12.

THE SIR JULES THORN CHARITABLE TRusr
REPORT OF THE TRUSTEES
FOR THE YEAR ENDED 31ST DECEMBER 2024
Trustees, respI￿51b•1ltjes in relati¢)n to the finandal statements
The Trustees a￿ responsible for preparing the Trustees. Annual Report and financial statements in
accordance with applicable law and United Kingdom Generalfy Accepted Accountiig Practice Iunited
Kingdom Accounting Standards).
The law applscable to charities in England ènd Wales requlres the Trustees to prepare financial statements
for each financlal year which give a true and fair v￿W of the state of affairs of the charity and of the
incoming resources and application of resour￿ of the charity for that perw)d. In preparing these financial
statements, the Trustees are required to-
Select suitable accounting polic*s and then appty them consistentlv:
Observe the methods and principles in the Charities SORP:
Make judgements and estimates that are reasonable and prudent:
Slale whether applicable accounting stsndards have been follthved. subject to any departures distbsed
and explained in the financial statements- and
Prepare ihe financial statements on the 80in8 concern basls Unle￿ it is inappropriate to presume that
the charlty will continue in business.
The Trustees are resp)nsible for keeping adequate accounting ￿CordS that a￿ sufficient to show and
explain the charity's transactions. disclose with reasonable accwracy at any time the financial position of
the charity and enable then to ensure that the finantial statements compty with the Charity's constitution.
They are also responsible for safeguarding the assets of ihe charity and hence for taking reasonable steps
for the prevention and detection of fraud and other irregularity.
Auditor
Haysmacintyre LLP has indicated its williwiess to be ￿apPOInted as statutory audit for the next finanoal
year.
Approved by the Trustees and signed on iheir behalf by:
lizabeth Charal, Chairman
Date:
12

THE SIR JULES THORN CHARITABLE TRusr
REPORT OF THE TRUSTEE5
ST
FOR THE YEAR ENDED 31 DECEM8ER 2024
Independent auditorf5 rewt to the Trustee5 of the SirJulesTh¢Yn Charitsble Tryst
Opinion
We have audited the financial statements of The SirJules Thom Charitable Trust for the year ended 31
December 2024 which comprise the Statement of Financial Actfvities. the 8alance Sheet, the Cash Flow
Statement and notes to the financial statements. including a summary of SWdnifKant accounting policies.
The financial reportinB framework that has been applied in their preparation is applicable law and United
Kingdom Accounting Standards, including Financial Reporting Standard 102 The Financiol Reporting
St17ndord opplticoble in the UK ond Republic of Ireland Iunited Kingdorn Generally Accepted Accountlng
Practi￿1.
In our oplnion. the financial statements-
8Ne a true and fairview of the state of the charlvs affairs as at 31 December 2024 and of the charit¢s
net movement Sn funds forthe year then ended:
have been propedy prepared in accordance with United Kingdom Generally Accepted Accountlng
Practice. and
have been p￿pared In attordance with the requirements of the Charities Act 2011.
Basis for opinion
We have been appointed as auditor under Sect￿Tr 144 of the Charities Art 2011 and report in accordance
with the Act and relevant regulations made or having effect thereunder. We conducted our audit In
accordance with Internath)nal Standards on Auditing IUKI11SAs IUKII and applicable law. Our
responsibilities under those standard5 a￿ further deKribed in the Auditorfs ￿spOnsIbl1￿1es for the audit of
the financial statements section of our ￿pOrt. We a￿ independent of the charity in accordance with the
ethical requirements that are rekvant to our audit of the finanaal statements in the UK, including the FRCS
Ethical Standard, and we have fulfilled our other ethrcal resw)nsibilit*s in accordance with these
requirements. We beI￿ve that the audit evldence we have obtained ig sufficient and appropriate to provide
basis for our opinion.
Concluslons relatln8 to 8oin8 ¢1)ncern
In auditing the financial statements. we have concluded that the trustees. use of the going concern basis of
accounting in the preparation of the financial statements ts appropriate.
Based on the work we have performed, we have not Identified any material uncertainties relating to events
or conditTron5 that, individually or collectNely, may cast 5i8nificant doubt on the charity's ability to continue
as a going concern for a period of at least twefve months from when the financial statements are
authorised for issue.
Our responslbilities and the responsibilitres of the trustee5 Wlth respect to going concern are described in
the relevant sections of this report.
Other Inlormatlon
The trustees are ￿spOnSible for the other Informat￿n. The other information comprises the information
included in the Report of the Trustees. Our opinion on the financial statements does not cover the other
Information and, except to the extent otherwise explicitty stated in our report. we do not express any fomi
of assurance conclusion thereon.
In connectlon wlth our audit of the financwl statements, our resp)ftsibility ￿ to read the other information
and, in doing so. consider whether the other information is materialty inconsistent with the financial
statements or our knowledge obtalned In the audit or otherwise appears to be materially misstated. If we
13

THE SIR JULES ThORN CHARITABLE TRusr
REPORT OF THE TRUSTEES
FOR THE YEAR ENDED 31ST DECEMBER 2024
identify such material Intonsistenties orapparent material misstatements. we are required to determine
whether there is a material misstatement in the finanaal statements or a material misstatement of the
other informatlon. If. based on the work we have perfornied, we conclude that there ￿ a mater￿1
misstatement of this other inforrnatbon. we are required to report that fact. We have nothing to report in
this regard.
Matters on whlch we are requlred to rewt by exceptlon
We have nothing to report in respect of the following matter5 in relat*)n to whith the CharftSes (Accounts
and Reports) Regulat￿rts 2008 require us to report to you if, in our opinion:
• adequate accounting record5 have not been kept by the chèrity.or
sufficient accountin8 ￿CordS have not been kept- or
the charity financial statements are not in agreement with the accounting records and retum5; or
we have not ￿e1Ved all the inforniat￿n and explanations we require forour audlt.
Responslbllltles oftrumees for the fina￿la1 statements
As explained more fulty in the trustees. responsibilitie5 Statement set out on page 12. the trnstees are
responsible for the preparation of the financial statements and for being satiSf￿d that they give a true and
falr view. and for such internal control as the trustees determine 15 necessary to enable the preparation of
finanual statements that are free from material misstatement. whether due to fraud or error.
In preparlng the linancial statements. the trustees are re$F￿nsible for assessire the chariws ablllty to
continue as a 8oin8 concern, disclosi￿ as applicable. matters related to 8oin8 concern and using the going
concem basis of accounting unless the trustees either intend to liquidate the charity or to cease
operations. or have no realistic alternative but to do so.
Auditsrfs responslbilities far the au&rt of the financial statements
Our objettives are to obtsin reasonable assurance about whether the financial statements as a whole are
free from material misstatement. whether due to fraud or error, and to issue an auditorfs report that
Includes our opinion. Reasonable assurance is a high level of assurance, but t5 not a guarantee that an audit
conducted in atcordance with ISAS IUKI will ahways detect a material mi55tatement when it exlsts.
Misstatements can arise from fraud or error and are considered material rf. indNidually or in the
aggregate, they could reasonably be expected to influence the economic decisions of users taken on the
basls of these financial statements.
Irre8ularitie5, including fraud, are instances of non<ompliance with laws and regulations. We dess8n
pro￿du￿5 in line with our responsibilities. outlined al)o¥e. to detect materlal mlsststements in respect of
irregularities, including fraud. The extent to whKh our procedures are capable of detecting Irregularlties.
including fraud 15 detailed below-
Based on our understanding of the charity and the environment in whKh it operates, we identrfied that the
principal risks of non-compliance with Liws and regulations reL4ted to chartty law and GDPR. and we
considered the extent to which non-compliance might have a material effeci on the financial statements.
We also considered those laws and regulations that have a dlrect impact on the preparatlon of the
financial stateffients such as Charities Act 2011.
We evaluated managemenys incentNes and opportunities for fraudulent maniwlation of the finanaal
statements Ilncludlng the rlsk of overrlde of contro&. Audit wocedures perfomied by the engagement
team induded:
DisCU5sions with management including consideration of known or suspected Instan￿ of non-
compliance with laws and regulation and fraud..
14

THE SIR JULES THORN CHARITABLE TRusr
REPORT OF THE TRUSTEES
FOR THE YEAR ENDED 31ST DECEMBER 2024
Evaluating management's controts designed to prevent and detect irregularities,.
Identifyin8 and testin8 joumals. in particulariournal entries posted with hi8her risk of misstatement:
and
Challenging 0￿urnptlon5 and jud8ements made by management In their accounting estimates.
8ecau5e of the inherent limitstions of an audit, there is a risk that we will not detect all irregularitie5,
Includlng those leading to a material misstatement in the financial statements or non-compliance with
regulation. This rlsk increases the more that compliance with è law or ￿gulatIOn is removed from the
events and transartion5 reflected in the financial statements. as we will be ￿5S likely to become aware of
instances of non-compliance. The risk is also greater regarding irregularities occurring due to fraud rather
than error. as fraud Involves intent¥)nal cDncealmenL forgery. collusion, omiss¥)n or misrepresentatK)n.
A further desuiption of our responsibilities for the audit of the financial statements Is located on the
Financial Reportin8 Councifs website at- www.frc.or
.uk
auditor5res
onsibilitie5. This description forms
part of our audrtorfs reporL
Use of Our report
This report is made solely to the charitys trustees. as a body, in accordance with section 144 of the
Charities Act 2011 and regulations made under sertion 154 of that Act. Our audti woTk has been
undertaken so that we might state to the charrty's trustees those matter5 we are required to state to them
In an Audito¢s ￿p)rt and for no other wrpose. To the fullest extent pemittted by kiw, we do not accept or
assume responslblllty to anyone other than the chariVs trustees as a tx)dy forour audit work. forthls
report, or for the opinions we have fomied.
sma
LLP
ory Auditors
10 Queen Street Place
London
EC4R IAG
Date." 11 &o2S
Haysmac LLP is eligible to ￿t as an audltor In temis of settion 1212 of the Companies Act 2CM)6.
15

THE SIR JULES THORN CHARITABLE TRUST
STATEMENT OF FINANCIAL AcnvrnES
ST
FOR THE YEAR ENOEO 31 DECEMBER 2024
Unrestrirted
Funds 2024
Endo￿nt Total Fund5
FthMI 2024
2024
Total Funds
2023
INCOME AND ENDOWMENTS
Income from Investments
2,110,401
2.110.401
2,007,451
Totsl Income and Endowments
2.110,401
2.110.401
2,￿7,451
EXPENDITURE
Expendlture on ftalslng
Investment Management Costs
42,180
42,180
139,718
Expendlture on Charltable Actl¥ilie5
Grantmaking
Medical Research Grants
Research Infrastrurture
Improvements in Care
Small Donations Scheme
1.315.759
533.238
386,047
544.066
L315,759
533,238
386,047
S44.066
1,965,746
561,652
568,689
687,745
2,779,110
2.779.110
3,783,832
Totsl Expendlture
2.779.110
42,180
182L290
3,923,550
Net Operallng (Deficit} lor the Year
1668.7091
142,1801
1710,889)
(1.916,099J
Net Galns on Investments
8,655,915
8.655.915
5,443.803
Net In¢omellExpndlturel for the Year
Transfer Between Funds
{668.7091
668,709
.613,735
7,945,026
3.527.704
1668,7091
14et Movement In Funds
7.945,026
7,945,026
3,527,704
Reconciliatitin of
Balance brought lorward
As at l January 2024
Totsl Funds Carrled Forward
At 31 Decqmber 2024
111.908,9)8
111.908.908
108,381,204
119.853.934
119.853.934
111,908,908
The rtotes on poqe$ 19 to29Awm port rfthe5efinandalstotements
16

THE SIR JULES THORN CHARITABLE TRUST
BALANCE SHEET
ASAT 31" DECEMBER 2024
Notes
2024
2023
FIXED ASSETS
Furniture and Fittin
Investments
2,784
121.156.161
121,158.945
3,018
114.231,063
114.234,081
CURRENT ASSETS
Debtors & Accrued Income
Short-temi investments
Cash at bank and in hand
93.947
9,370.711
7,612,531
17.077,189
202,063
5,521.923
10.679,590
16.403.576
CREDITORS: amounts falling due
within one year
Grant Commitment5
Creditors
io
li
8.692,083
36,559
8.728,642
7,104.814
94,036
7.198,850
NET CURRENT ASSETS
8.348.547
9,204,726
TOTALASSEfs LESS cuRREP￿ IIABILMES
129,507,492
123,438.807
CREDITORS: amounts falling due after
more than one year
Grant Commitmenls
io
9,653.558
119,853,934
11,529,899
111,908.908
NEf ASSETS
12
THE FUNDS OF THE CHARITY
Endowment Funds
Unrestricted income funds
119.8S3,934
111.908.908
Total Charity Funds
119.853.934
111.908.908
The financial statements were appn)ved and authorised for issue by the Trustees and were svaned on
their behalf by-
Chairn)an
Date-
bA TL•ML
The notes p4we$ 19 to 29fvmi partolthesefinondolstotements
17

THE SIR JULES THORN CHARITABLE TRUST
CASH FLOW STATEMENT
FOR THE YEAR ENDED 31ST DECEMBER 2024
2024
2023
Net cash loutflowl from operating aCtI￿tieS
Net cash loutflowl from investing artibllties
(Decrease) in cash in the peritid
IA}
13,(X)8.735)
158.324)
13,067.0591
(3.453,812J
11,071,292J
f4,525.104J
Al Reconclllatlon of net income to net cash outh4
from operating activities
2024
2023
Net income for the year
Depreciation
Loss Iprofitl on the disposal of T￿ed assets
Management fees paid from endowment funds
(Gains) on Investments
Dividends and interest from investments
IGainsl on short-term investments
Interest income
Decreaselllncrease) in debtor5
(Detreasell Inuease in creditor5
Net tssh loutflow) from operatin8 activities
7,945,026
1,283
3.527, 704
2,266
(6)
147,599
15,427,341J
(1,544.622J
f21,9231
(429,947}
{102,058J
394.516
102.451
18.257,127)
(1.770.422)
(398,7881
1392,726)
108,116
{346.5491
13,IY)8,735)
(3,453,812J
Bl 14et cash louthow) inflow from ifbvesting •cli￿￿e$
2024
2023
Cash withdrawals from investment wJrtfolKJ
Interest income
Purchase of short-term investments le55 withdrawals
Purchase of tangible fixed assets
Disposal of tangible fixed assets
3,000,000
392,726
13,450.0fy))
11.050)
4,0￿,(*%•
429.947
15,5(KJ.0001
fl.619J
380
(1,071.2921
158.324)
C) Analysis of change5 in net Ush funds
At31
December
2024
At ljanuary
2024
Ca5hflow5
Cèsh in hand
10,679,5
13,067.0591
13,067.0591
7,612,531
7,612,531
Total tash and cash equivalents
10,679,590
The notes on pages 19to 29fvmipqrt olthestfinondolstotements

THE SIR JULE5 THORN CHARITA8LE TRUST
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENOED 31ST DECEMBER 2024
L PRINICIPAL ACCOUNnNG POUCIES
8asis olaccounling
The Trust is a registered charty in England and Wales and as such is a Public Benefit entity. Govemed by its
Trust Deed. dated 18 February 1964.
The Trusvs Charity Commission registration number is 233838 and its registered address is 24, Manchester
Square, London, WIU 3TH.
The financial statements have been prepared under the historical cost COnvent￿n as modffied by the
revaluation of investments and in accordance with Accounting and Reporting by Charities: Statement of
Recommended Practice ISORP 20191 applicable to charriie5 preparing their accounts in accordance wf(h the
Financial Reporting Standard applicable in the UK and Republic of Ireland IFRS 1021 and the Charities Act
201L
The functional currency of the Trust is considered to be GBP because that is the currency of the primary
economic environment in which the charity operates.
After making enquiries. the Trustees have a reasonable expectation that the charity has adequate resources
lo continue its artivities for the foreseeable future. The trustees are not aware of any materlal uncertainties
about the charit(s abiltty to continue and accordin8ty, they consider it appropriale lo adopt the going
concern basis in preparing the financial statement5 a5 outlined in the Statement of Tru5tees' Responsibilities
on page 12.
b? Crltkal occoufttlnqAudqenpents •ndkey sources of estlmotlon uncertalnty
In the application of the charirf5 accounting policbes, which are desuibed in this note, Trustees are required
to make judgements. estimates and assumptKJns about the carrying values of assets and liabilitie5 that a
not readily apparent from other source5. The estimates and undertying assumptions are based on historical
experience and other factors that are conskjered to be relevant. Actual results may differ from these
estimates.
The estimates and undedying assumptions are feyiewed on an on-golng basb. Revlsions to accounting
e5timate5 are reco8nise(l in the period in which ihe estimate is revised rf the revision affects only that
period, or in the period of the revision and future periods.
In the view of the Trustees, no assumption5 conceming the futu￿ or estimation uncertainty affecting assets
and liabilities at the balance sheet date are likety to result in a material adjustment to their carrying
amounts in the next financial year.
19

THE SIR JULES THORN CHARITABLE TRusr
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 315T DECEMBER 2024
CJ Incomefrom Investments
Dlvidend. interest and other Income is accounted for on an accruals basis and is shown gross of any
associated tax credits recoverable.
d) Galns/(lossesJ on inVestn￿nts
Realised gains and losses on investments are cakulated as the drfFerence between sales proceeds and
purchase value. Unrealised gains and losses are cakulated as the difference between their fair value at year
end and their purchase value.
ej Grants onddonotlons payable
Grants and donations are recognised in the Statement of Financial Activitie5 based on the commitments
made during the year. Because most projects last for more than one year the total of amounts commrtted
but not yet paid is shown split between current and knn8-temi liabilitles.
Flxed ossets ond depreclotlon
Fixed assets over £500 are capital￿ed. Depreciation is provided on fixed asse15. in order to write off the
COSt of the a55ets over their expected useful Irles estimated resKlual Values, at the folbwing rates:
Office equipment
Fixtures and fittings
20% p.a. straight line
20% p.a. stral8ht line
qj Investments
Investments are stated at mld-market value at the year end. The Statement of Financial ActNities Includes
the aggregate of reali5ed and unrealsed galns and losse5 during ihe year.
hj 80sls of amocotion olcosts
Cost oARai5ing Funds
The cost of raising funds represents amounts paid to the Trust's external investment managers.
Support costs
These costs are incurred directly in the delsvery of the Trusl'5 charitable actrvities. These costs are based on
the percentage of time that a resource is used in the application of grants admin￿tratIon and associated
activities together with the overhead costs of the charity-
Governonce costs
Governante costs comprlse costs Inajrred in Trust adminlstratlon and tomplbance with regulatory
requirements. Staff costs are calculated a5 a percentage of time committed.

THE SIR JULES THORN CHARITABLE TRUST
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENOEO 31ST DECEMBER 2024
IJ Portfvlio managementfres
The cost of managing the TNst's investment portfolio is met frorn Endowment Funds. Portfolio
management fees are re¢u8nTr5ed on an accruals basis.
i)
Employee 8enefits
Where employees have rendered service to the charity short-tem employee benefits, including holiday pay.
to which the employees are entitled are charged to the Statement of Financial Activities in the year to which
they relate.
COntrib￿lorI5 were made to all employees. personal pension schemes in accordance with their employment
contract5. All such contributions are expensed throu8h the Statement of Financial Activities in the year in
which they are due.
kj
Funds
Endowrnent funds represent the investment assets derived from the Original gift from Slr Jules Thom. The
endowment is expendable at the discretion of the Trustee5.
IJ Flnancial lftstruments
Financial assets and financial liabilities are reco8nised when the Trust becomes a party to the contractual
provisions of the instrument. Additionally. all financial assets and liabilities are classrfied according to the
substance of the contractual arrangements entered into.
Financial assets, comprised of cash. other debtors and accrued intome. and financial liabilities, comprised of
grants payable, other creditors and accruals. are inttially measured at transartion price (including
transaction costs) and are subsequently re-measured Whe￿ applicable at amortised cost except for
investments which are measured at fair value with gains and losses recognised in the Statement of Financial
Activities.
The Trusvs investment managers enter into forward rate currency contracts to manage it5 exposure to
fluctuations in exchange rates within the investment portfolio throughout the year. These contracts are
recogni5ed at fair value within the overall valuation of the investment portfolio with galns or losses
recogni5ed in the Statement of Financial ActV4ities.
Assets and liabilities held in foreen turrency are Iranslated to GBP at the balance sheet date at an
appropriate year end exchange rate.
2. INCOME FROM INVESTMENTS
2024
2023
Listed investments
Cash interest income
1,717,675
392,726
2,110,401
1,577,504
429,947
2,007,451
21

ThE SIR JULES THORN CHARITABLE TRUST
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31ST DECEMBER 2024
3. ANALYSIS OF TOTAL EXPENDrruRE
Med5cal
Ralslby researth
lunds
grants Infrastrurture
Ann Rylands
Small
Totsl
Donations ExpendSture
5nCa
2024
Investment Management
Fees
Grants Awarded
Staff Costs
Support Costs
Governance
2024 Actl¥lty Total
42.180
42,180
394.050
2.343.644
75,591
192.490
43,329
150.159
31,096
92,817
544,066 2,821,290
1.169.594
49.582
65.49)
31,(P33
42.180 1,315,759
465,IX(I
33,223
19.701
15.314
S33.238
315.(MXJ
21,639
15.314
386.047
2023
Investment Management
Fees
Grants Awafded
Staff Costs
Support Costs
Governance
2023 Artivbty Total
139.718
139,718
3,367,999
168.510
137,284
110,039
3,923,550
1835,986
37.489
55.408
36,863
139.718 1,965,746
492.963
29.381
21.IS2
18.156
561,652
St￿,c￿X}
29,381
21,152
18.156
568.689
539,050
72.259
39,572
36.864
687.745
Full detoils of gronts oworded in the yeor ore on page$ 30 to 34 of this report

THE SIR JUiES THORN CHARITA8LE TRUST
NOTES TO THE FINANCIAL STATEMEKrs
FOR THE YEAR ENDED 315T DECEMBER 2024
2023
SUPPORT COSTS
staff Costs
Rent. rates and seNice ¢har8es
Other
192,490
55,gJ)
94,259
342.649
168 510
305.794
Governance costs
Staff costs
Trustees & Peer Reviewers Expenses etc
Other
Audit fees- current year
Legal Fees
58,835
790
8,315
23,100
1,777
92.817
78,426
1.221
5.192
25,200
110.039
Total Support and Go¥ernan¢e ¢osts
435,466
415,833
2024
2023
4. STAFF COSTS
Salaries
Employer's National Insurance
Pension and Death in Service Contributions
215,479
19,777
16,069
251.325
212,741
19,114
15,081
246.936
The numtor of employees whose emoluments are abovè £60.OW during the year was:.
No.
EIIO,CMXJ- £120,CKK)
The avernge weekly number Iheadcountl of persons employed by the charity duiin8 the year was..
No.
No.
Administralion and Governance
The total amount of employee benefits received by key management in the year ended 31st December 2024
was £137.16712023- £129,946J including EmployeT'5 National Insurance Contributions.
TRusfEES
2024
2023
Total emoluments
Nil
Total reimbursement of expenses
582
3 Trustees received travel aThl merfing expenses in the year12023- 4 Trusiees- £5821.

THE SIR JULES THORN CHARITABLE TRUST
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31ST DECEMBER 2024
5. RELATED PARTIES
There were rto relaied party transactions or balances which require dixlosure withln the financial statements
during 202412023- £Nil}.
6. TANGIBLE FIXED ASSET5
FittinKS and
Equlpme
Cost l January 2024
Additions
Disp05a15
At 31 December 2024
33,652
1,050
111.9831
22.719
Depve¢i•tlon
At l January 2024
Charge for the year
Disposals
At 31 Deomber 2024
30,634
1.283
111.9821
19,935
Net Book Value
At 31 December 2024
1784
At 31 December 2023
3.Q18
24

THE 51ft JULES TrIORN CHARITABLE TRUST
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31ST DECEMBER 2024
7. IfivESTMEP4TS
2024
2023
Market value at l January 2024
Investment income rewved and reinvested
Cash funds withdrawn
114.231,063
1.770,422
I3,c￿.(1X1>
113.LN)1.485
8.257,127
1102,4511
121,156,161
125.269.691
111.406,699
1,550,083
(4.000.OLXI)
108,956,782
5,421,880
(147.599)
114,231,063
127,115.674
Net movement in investment cash balances
Net gains I Ilossesl on investments
Net Management fees paid
Market value at 31 December 2024
Cost at 31 December 2024
Investments at year end were made up as follows:
2024
2023
UK equities
UK fixed Interest securities
Overseas equitles
Overseas fixed interest securities
Mana8ed fiinds
Fonmard foreign exchange
Other
Cash
1,915.376
4,865,014
3,758,930
3.862,033
97.252.259
112.719
1.3S9.045
1.105.687
114,231,063
121.156,161
121.156.161
On 4th September 2024 the individual investments managed by Ruffer on behalf of the Trust were
placed in the Ruffer Charity Asset Trust.
Portfolio Management Fees
Investment management fees incurred in the yearwere:
ftuffer
Sarasin- Fees Rebated
Net charge to SOFA
2024
2023
207.547
1165,3671
42.180
288,551
f148,833J
139.718
Fees Arrangement with Sarasin
Included in the c05t of units held within this fund Is an embedded fee. This fee is higher than that agreed
by the Trustees and so the fund manager make5 a rebate directly io the fund. which 15 reinvested in
additional units.
FoNard contracts
There were no foryiard rate contracts at 3tst December 2024. At 31st December 2023 the Trust was
committed to selling USD to the value of £8.988.844 under forward rate contracts. These matured on
11.01.24. The sUrp￿S of £112.719 derived from the contracts was re-invested in the portfolio.
These commitments were embedded in the investment funds managed by Ruffer at December 2023.
There were no other forward commitments outside of the Ruffer rnanaged funds.

THE JULES THORN CHARITABLE TRUST
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31ST DECEMBER 2024
8. SHORT-TERM INVESTMENTS
2024
2023
Markel value at l January 2024
Cash funds added I Iwithdrawnl
Net gains / Ilossesl on Investments
Market value at 31 December 2024
Cost at 31 December 2024
All short-term investments are held in managed funds.
5.521.923
3.450,(Xrf)
398,788
9.370.711
8.983.596
5.500,0
21,923
5.521,923
5,51XI,000
9. OEBTORS
2024
2023
Accrued income
Prepayments
26,520
67,427
93.947
144.039
58,024
202.063
10. GRAPIT COMMITMENTS
2024
2023
Forward commitments at l January 2024
Commitments made duringthe year
Grants made in previous years rescinded or cancelled
Adjustments re Grants made in Previous Year
Arnounts paid durlng the year
FoThvard commltments at 31 December 2024
18,634,713
2.695.756
1780.3231
34,162
(2,238.6671
18.345.641
18,238,120
2.821.912
7,037
12,432,356J
18,634.713
Forward commltments at 31 December 2024 in respect of
on8oing projects were as follows..
50th Anniversary Award
Medical Research Grants
Previous Capttal Grant Programrne
Research Infrastructure Fund
Innovation and Improvements in Health and Care Fund
4,999.999
9,893.262
1,3CwJ,065
1,146.535
1,005.780
18.345.641
5.LXiI.000
9.762.475
2.102.079
920,159
850.LhXI
18,634,713
Spllt as lollows:
Amounts due within one year
Amounts due between one and five yea
Amounis due after more than five years
8.692,083
9,541,654
111,904
18.345.641
7.104.814
11.371.359
158,540
18.634,713
11. CREDITORS
2024
2023
Trade Creditors
Accruals
Portfolio management fees
8.431
28.128
4881
35,617
53,538
94,036
36,559

THE SIR JULES THORN CHARITABLE TRUST
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31ST DECEMBER 2024
MALYSIS OF NEf ASSETS BETWEEN FUNDS
12a. ANALYSIS OF NET ASSETS BETWEEN FUNDS 2024
Tanglble
Hxed Asses
Other Net
Llabllltles
Total
Funds
Unrestricted funds
Endowment funds
Total fvnds
121.156,161
121.156.161
2,784
2.784
11,305,011) 119,853,934
{1,305,011) 119,853,934
ANAL YSIS OF hlEfASSETS BETWEEN FUNDS 2023
Investments Tonqlble
FlxedAsses
Other Net
Lknbllltles
Total
Funds
Unrestrirtedfvnds
Endowmentfvnds
Totalfvnds
114,231,063
114,231,063
3,018
3,018
12,325.173) 111,908.908
12,325,173J 111,908,908
Izb. RECONCILIATION OF FUNDS 2024
Funds bllwd
at 1.1.24
In￿me Expendlture
Translers
Gains and Funds clfwd
Losses
at 31.12.24
Endowment funds
Unrestritted funds
111.908.908
142,1801 1668,7091
2,110,401 12,779,110)
668,709
111,908,908 2,110,401
12,821,290}
8.655,915 119.853.934
,655,915 119,853.934
RECONCIUAnoN OFFUNDS 2023
Funds b/fvd Inconje Expendlture
otl.1.23
Transfers
Galns and Funds c/fvd
Losses
ot 31.12.23
Endowmentfvnds
Unre5trirtedfunds
108,381.204
(139.718) 11.776,381J
2,IX17,451 13.783.832) 1.776.381
108,381,204 2,LkJ7.451
(3.923,550)
5.443.803 Ill,￿8 908
5,443,803 111,908,908
The Endowment funds represent the investment assets derpled from the or*inal gift from Sir Jules Thorn. The
endowmeni is expendible at the discretion of the Trustees. The Trustees have authorised an additional transfer
from the endowment to unrestrlcted funds in order io finance granis awarded in the year.

THE SIR JULES THORN CHARITABLE TRUST
NOTES TO THE FINANCIAL STATEMENTS
FOR ThE YEAR ENDED 31ST DECEMBER 2024
13. OPERATING LEASE COMMITMENTS
Total fvture minimum lease payments due under non<ancellable opernting leases at the end of
the year are as follows:
2024
2023
Land & Buildin85
Due not later than one year
Due later than one year but not later than fpie years
Total future minlmum lease payments
57.(KX)
201,379
258,379
Lease payments recognised as an expense in the year totalled £44.682 {2023.. £47.LIJOJ.
Plant and equipment
Due not later than one year
Due later than one year but not later than fNe yea
838
1.047
Total futu￿ minimum lease payments
1,047
1.885
Lease payments recogni5ed as an expense in the yeartotalled £83812023.. £8381.

THE SIR JULES THORN CHARITABLE TRUST
STATEMENT OF FINANCIAL AcllviTIES
FOR THE YEAR ENDED 31ST DECEMBER 2024
14. COMPARATIVE STATEMENT OF FINANCIAL StATEMEt4TS
Unrestrirted
Funds 2023
Ednowment
Fund 2023
Total Funds
2023
INCOMÈ AND ENDOWMEpirs
Income from Investments
2.007.451
1007.4SI
Total Income and Endowments
2.007.451
2,007,451
EXPENDITURE
Expendlture on Ralslng Funds
Investment Management Costs
139.718
139,718
Expenditure on Charitable Arti¥ities
Grantmaklng
Medital Research Grants
Research Infrastructure
Improvements in Care
Small Donations Scheme
1,965,746
561,652
568,689
687.745
l965,746
561,652
568.689
687.745
3.783.832
3.783,832
Totsl Expendllure
3,783.832
139,718
3.923,550
Net Operatlng (Delkit) for the Year
{1.776.3811
{139,718)
IL916.099)
Net Galns on Investments
5,443.803
5.443.803
Net Incomel(EMpendlture) for the Ye¥
11.776.381)
5.304.085
3,527,71J4
Transfer Between F￿d5
1,776.381
11,776,381}
Net Movement In Funds
3.527.704
3.527,704
Reconcillatlon of Funds
Balano brought fonvard
Ast 1° January 2023
108,381,204
108.381,204
Totsl Funds Carrled Forward
At 31 1)ecember 21r13
Ill,￿8.908
111,908,908

THE SIR JULES THORN CHARITABLE TRUST
NOTES TOTHE FINANCIAL STATEMENTS ICONTINUEDI
FOR THE YEAR ENDED 31sr DECEMBER 2024
2024
MEDICAL RESEARCH GRANTS
THE SIR JULESTHORN AWARD FOR MEDICAL RE￿ft(H
Unl¥ef51ty of Oxford
Development of tools to Measu￿ and predict dincial trajectories of seve
mental illne55
5-year project
1,695,757
Unlverslty of Birmin8ham
Definin8 new treatment and headache mechanisms in raised intercranial pre55ure
Extension to 2019 grant for covid
19.801
PhD Stholarshlps
Extension of UCL studentship awarded in 2019 under previous PhD prograrrffie
14,546
Unlverslty Coll•ge London
2016 Sil Jules Thorn Award rescinded. Trust fijnding not required to complete
remainin8 work.
1560.3251
Adjustments to Commitments made tn prhiryears for underspent awards
11851
Total med1￿1 Rese￿ Awards
Ll
RESEARCH INFRASTrUCTURE FUND
University of Bimiln8ham
Platform to develop complex. multi-organ human disease modèls
299,000
Unlvetsity of Essex
Creation of a translational resèarch irradiation faciknty
166,000
Total Research Infrastructure Fund
MEDICALLY RELATED CAPITAL AWARDS
INNOVAnoN ANO IMPROVEMEP4T IN HEALTH AND CARE
Guy's and Styh￿3$'S NH5 Tn
Roll-out of a digital tool to streamline pre-oper8tive 8ssessmonts for pati¢nt¥
ahead of scheduled surgery
235,000
Unlverslty ol Strathdyde
Expansion of technology-enabled model for stroke ￿habIlItati.On
300.C(10
Adjustments to commltments made In wloryeays for 2 awards that dld not start
The Chlldren's Trust
Development of new Trnterdisciplinary care model for children with neurtrdisabillty
1120.0001
Noltintham UmeNty Hospltals NHS Tntst
Children's Lun8 Testin8 Hub
1100.cooi
Total Inno¥ation and Impm4*m•rt In Health and Care
315.OlX>
TOTAL

THE SIRJULESTHORN CHARITABLETRUST
NOTES TO THE FINANaAL sTATEmE￿r5 ICONMNUEDI
FOR THE YEAR ENDED 31ST DECEMBER 2024
THE ANN RYLANDS SMALL DONATIONS GRANT PROGRAMME
Award Amount
Number
Total
£3,IXJO
£2.500
£2,050
£2,000
195,(XX)
105,C
2.050
92,(KJO
42
46
154
394,050
THE ANN RYLANDS SMALL DOP4ATIONS GRANT PROGRAMME (Detailedl
NUMBER
Chrls Westwood Charity for Children with Physical Disabilities
Wag and Company
e Concem North Norfolk
Tourette Syndrome IUKI Assotiaiion trading as Tourettes Artion
The Peter Pan Centre
Home-Start Wessex
UsinaBus
Listenin8 Books
Amaze
Daisy's Dream
Chapter West cheshi￿ Ltd
Positive Help
Tom's Trust
Wornan's Trust
Children on the Autistic Spectrum Parent's Association
Springboard Opportunity Group
Medicinema
Music in Hospitals & Ca
Home-start Arun. Worthin8 and Adur
BOSP Bri8hter Opportunitie5 for Special People
Safeline
Musical Connecth)ns
The Salvesen Mlndroom Centre
Farnilies United Network
Leeds Mencap
Time Out Group INorthWest}
The Kent Multiple Sclerosis Therèpy Centre Ltd
Hearts and Minds Ltd
Oakleaf Enterprise
Stick'n, Step
3,000
3.0(NJ
3.0
io
li
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
3,000
3,000
3,000
3.000
3.000
3,tsJO
3.thjo
3,(KlO
3.000
3,000
31

THE SIR JULES THORN CHARITABLE TRUST
NOTES TO THE FINANCIAL STATEMENTS ICONTINUEDI
FOR THE YEAR ENDED 31ST DECEMBER 2024
THE ANN RYLANDS SMALL DONATIONS GRANT PROGRAMME
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
Compass Thernpy Support Communlty Llmited
Clear Sky Children'5 Charity
Young Roots
Space4Autism
Alive Actwities Ltd
Hospicecare North Northumberland
The Neuromuscular Cent
Asthma Relief
Bendri88 Trust
Cerebral Palsy Scotland
Special Needs And Parents Ltd
Famity SUp￿rt Derbyshlre
Create (Arts} Limited
The Mulberry Centre
The Spiti Charitable Trust
Soundwell Music Therapy Trust
Little Hearts Matter
SURVIVE (Support for Survlvors of Rape and Sexual Alwse)
sutton Vlsion
Barons Court Project
Go Beyond Chartty
Caxton Youth Organisation
Risin8 Sun Domestic Violence and Abuse Service
Compaid Trust
Blue Smile Projert
Dame Vera Lynn Chiklren's Charity
Our Special Friends
LinkAble Woking
British LNer Trust
Stanley Grange Community A550cialion
Jigsaw South East
8ucksWision
ERIC. The Children'5 Bowel and Bladder Charity
Kangaroos Mid Sussex
Swindon Carers Centre
3.000
3.000
3.000
3,000
3.000
3.000
3,000
3,000
3.000
3.000
3,(KlO
3,LKIO
3,IXIO
3.c￿0
3.lYJO
3.(￿0
3,000
3,000
3.rxio
48
49
50
51
52
53
54
55
56
57
58
59
3.0
3.oc
61
62
63
3,000
3,lYJO
65
Home-start H48h Peak
Age Concern Twyford & Oi5trirt
Conlact
Changin8 Faces
Age UK Exeter
The Basingstoke and Alton Cardlac Rehabilitation Charity Ltd
Age Well East
Parity for Disabilty
2.500
2,5(Kl
67
69
70
71
72
73
2.SC
2,5C
2,5CKJ
2.5(Kl

THE SIR JULES THOR14 CHARITABLE TRUST
NOTES TO THE FINANaAL STATEMENTS ICONTINUEO)
FOR THE YEAR ENDED 31ST DECEMBER 2024
THE ANN RYLANDS SMALL DONATIONS GRANT PROGRAMME
74
Age Concern Mole Valley
75
brainstrust
76
Children'5 Bereavement Centre
77
The Burrough Harmonycentre
78
Memories are Golden
79
Trekstock Llmited
80
Perth Autism Support
81
4Sight Vision Support
82
Team Oomenica
83
Sirona Therapeutic Horsemanship
84
Child￿n with Cystic Fibrosis Dfeam Holidays
85
Lothian Autistic Society
86
Young Carers Developrnent Trust
87
TRACKS Autlsm
88
Brain Tumour Support
89
The Anne Robson Trust
90
Sebastian's Action Tmst
91
Living Options Devon
92
The Living Room
93
SWALLOW- South West Action for Learning and Living Our Way
94
Southside Famity Project
95
The Harbour
96
Foundation For CondurtNe Education
97
Cavendish Cancer Care
98
CancefWiSe
99
The Isle of Wight Society for the Blind
100
Age UK Waltham Forest
ioi
Swindon Therapy Centre
102 Venture Scotland
103
Lom and Oban Heakhy Options
104
Open Country
105
Aware Defeat Depression
106 Winchester Youth Counselling
107 Cancercare North Lancashire and South Curnbria
2.500
2.500
2.500
2.500
2,500
2,500
2,500
2,500
2.5fy)
2,5
2.5LK)
2.5
2.5
2.5CKI
2,5(K)
2,5C
2.5
2.5CQ
2.5CiI
2,5
2.5
2,51K)
2,5(M)
2,500
2,500
2,500
2,500
2,500
2,500
2.500
2,500
2,500
108 Autism Nl
2.050
109
iio
iii
112
113
114
115
Hope for Tomorrow
Mind in Harrogate District
Headway Nottingham
Aphasia Support
Wirral Mencap
Cornwall Mind
Young People and ChikI￿n First
2,000
2,000
2,000
2,000
2,ClJO
2,000

THE SIR JULES THORN CHARITABLE TRUST
NOTES TO THE FINANaAL STATEMENTS ICONTINUEDI
FOR THE YEAR ENDED 31ST DECEMBER 2024
THE ANN RYLANDS SMALL DONAMONS GRANT PROGRAMME
116 Age Concern Cheshire
117
SELFA Children's Charty
118
Relate Avon
119
Aberdeen Day Project Ltd tla The 8readmaker
120
Dementia Support Hampshire & low
121
The Together Project
122 Mental Fight Club
123 UK Westminster
124
Together Collective
125
Bardet
126 Sheffield Women's Counselling and Theraw Service
127
Firsthand Lothhan
128 Gareloch RDA group
129
British Disabled Angling Association
130 Chilterns Neuro Centre
131
Warwickshire YOU￿ Care
132 Brighton Women's Centre
133
Activity Club for Children with Special Needs
134
Essex Respite & Care Assoclatlon
135 Cancer United
136 CHIPS
137
West Kent Mind
138 Downright EX￿lIent IDEX)
139 Dyscover Ltd
140
Held In Our Hearts
141
Rosie's Trust
142 Special Educational Needs Advice Centre
143 Youth Adventure Trust
144
South Manchester Down Syndrome Support Group
145
Samson Centre
2.0(XJ
2,0(KJ
2,OCQ
2,0(Kl
2.000
2.000
2.1)00
2,000
2,000
2,000
2,000
2,0(K)
2.OLKI
2.OLKJ
2.OCKJ
2.oc
2.OCKJ
iorKJ
2.OCK)
2.000
2.000
2.000
2,000
2,000
2,(KJO
2.1)00
2.000
2.000
2.000
2,000
2.000
2.000
2,000
2.000
2.000
2.C(10
146
Just Drop
147 Head2Head Thealre
148 Vislon Care for Homeless People
149 Openstorytellers Limited
150 Special Need5 and Parent Supwrt {Yorkshirel CIO
151
Youth Talk Limited
152
Headway Surrey
153 Suffolk Accident Rescue Service (SAR51
154
Eczema Outreach Support
TOTAL AWARDS MADE IN THE YEAR
394,050