The AMR Narrative Unaudited Annual Report Year Ended 31 March 2024
The AMR Narrative Annual Report Year Ended 31 March 2024 Contents Page Reference and Administration Details Trustees, Report Chartered Accountant's Report 10 Statement of Financial Activities Statement of Assets and Liabilities 12 Notes and Accounting Policies 13-14
The AMR Narrative Reference and Administration Details Year Ended 31 March 2024 Charity Namg and Number The AMR Narrative registered charity number 1204055. Truste9$ The Trustees who served during the year and up to the date of approval of these accounts were as follows.. Dr F Chiara Prof M Mendelson Dr A Brink Dr O Van Hecke Dr R Coetzee Dr E Charani Dr W Thompson (Chairperson) Prlnclpal Address Suite 3f Peel House 30 The Downs Allrincham WA14 2PX Bankers Unity Trust Bank plc Four Brindleyplace Bimiingham B1 2JB Accountants Francis Clark LLP Sigma House Oak View Close Edginswell Park Torqu8y Devon TQ2 7FF
The AMR Narrative Trustees, Report Year Ended 31 March 2024 Trustees Roport The trustees present their report for the year to 31 March 2024. ObjectlVg$. Activities and Public Benefit As per our constitution, our charitable objectives are.. For the public benefit, to advance education among the public, medical practitioners, patients, and others, about antimicrobial resistance (AMR} through the provision of educational resources, programmes, advocacy development, community building and tools including a website, social media campaigns, webinars, events, and other media. The Trustees have regard to the Charity Commission's guidance on public benefit. AMR is a natural phenomenon where microorganisms such as bacteria, viruses, fungi, and parasites evolve lo become resislanl lo the drugs that are used lo Ireal them. This means that drugs become less effective or completely ineffective in Irealing the infections caused by these resistant microorganisms. Whilst our charity is registered in the UK, we prefer to take a global approach, acknowledging that antimicrobial resistan IAMRI is a worldwide issue that impacts everyone. We also understand the importance of partnerships in addressing the complexities of AMR and saving lives. This is why we are committed to fostering meaningful relationships with other patient groups, civil society leaders, academic institutions, industy stskeholders, and others. Structure, Govemance and Management Structure and Governance The AMR Narrative is a registered charitable incorporated organisalion, registered under the number 1204055. and was established under a scheme of the Charity Commissioners dated 20 July 2023. The constitution requires there to be a minimum of three Trustees and there is no maximum number of charity trustees that may be appointed to the CIO. In June 2024, Marc Mendelson resigned, and a new legal trustee, Jonathan Green was appointed which will be included in our next annual report. The charity had no employees nor paid any remuneration during the year and no trustees are trustees of any other organisation. Management Day-to-day operation of the charity, and strategy implementation, is delegated lo the executive director, who is supported by the Iruslees, an independent advisory board, paid consultants and a volunteer. In the first financial year, no paid staff were employed. New trustee appointments Upon appointment of new trustees, we undergo a formal application process. During their induction meeting, minutes are recorded, and a resolution is passed al a properly convened meeting of the charity trustees. We present an overview of the charity, recent activities and explain its strategic objectives, as well as providing a rinancial overview. New Iruslees are also briefed on and sent the constitution document and internal policies which at present includes our safeguarding policy, financial procedures policy, conflict of interest, social media and data protection policy. Considering our aim lo diversify expertise of our board we appointed a trustee with a legal background OLJtside of the first financial year on the 11th of June 2024. Each Iruslee (including the first charity trustees) must be appointed for a five-year term with the board having the option to appoint the trustee for a second term of five years at the expiration of the first term.
The AMR Narrative Trustees, Report (continued) Year Ended 31 March 2024 Chair's Foreword It is with considerable pleasure that I wrf(e this foreword for our first Annual Report. As Chair of The AMR Narrative, il is both a privilege and a responsibility to reflect on the work we have undertaken as a newly established charity. Under the outstanding le8dership of our Founder and Chief Executive, Vanessa Carter, and with the dedication of my fellow founding trLJStees, we have sel the stage for a vital mission.. raising awareness, building advocacy capacity, and fostering 8 global community to address one of the most critical challenges of our time. In our few months, we laid strong foundations. This document serves as a resource, demonstrating our commitment lo making antimicrobial resistance IAMRI an issue that is understood by everyone-from patients and the public lo policymakers and health professionals. Vanessa's vision, shaped by her own lived experience of ballling resistant infections and extensive advocacy, has guided our efforts in building an organisalion that places people at ils heart, ensuring that those affected by AMR have their voices amplified on the global stage. This past year has been one of growth, and strategic planning. We have engaged with experts, partners, and global stakeholders to ensure our work is grounded in eviden and inclusivity. As we look ahead, we are eager lo expand the geographical reach and depth of our projects, continuing lo deliver impactful initiatives such as our Narratives Matter and the A-Z of AMR directory, and expand our patient engagement through webinars, events and social media. Our joumey has only just begun, but our ambitions are clear.. lo provide meaningful education, advocacy, and support lo all those impacted by AMR, while driving coordinated efforts lo miligale its devaslaling effects. None of this would have been possible without the dedication of our trustees, advisors, volunteers, and the generous support of our funders, for whom we are immensely grateful. As we chart the path fotward, l am filled with optimism and delerminalion. Together, we can Iransfomi the narrative around AMR, ensuring a healthier and more equitable future for all. Dr F Chiara Chairperson
The AMR Narrative Trustees, Report (continued) Year Ended 31 March 2024 What is antimicrobial resistance (AMRI? AMR or Antimicrobial Resistance, is a natural phenomenon that occurs when microorganisms {germsl - such as bacteria, fungi, viruses, and par8siles - evolve in ways that make the medicines designed to kill them less effective. These germs develop resistance to treatments, making infections significantly harder to cure. To understand this beller, think of antimicrobials as a group of medicines designed to target various types of germs. Different antimicrobial medicines are used for different types of germs, and typically.. ANTIBIOTICS ANTIFUNGALS ANTIVIRALS ANTIPARASITICS are used to tre3t infections caused by bacteria. are used to treat infections caused by lungi. are used to treat infections caused by viruses. are used to treal infections caused by parasltes. When germs become resistant lo anlimicrobial medicines, infections become more difficult to treat, leading lo longer illnesses and higher risks of death Imortalityl or disability Imorbidityl. One of the major contributors to AMR is the inappropriate use of anlimicrobial medicines. For instance, antibiotics are sometimes used for illnesses like the flu, Colds, and COVID-19, which are caused by viruses-nol bacteria. Since antibiotics Can't kill viruses, using them for these conditions is not only ineffective bul also harmful. This misuse gives germs the opportunity lo become resislanl to anlimicrobial medicines, making future infections harder lo Ireal. According to a recenuy published GRAM report (Global Report on AMRI, in 2019 close to 1.3 million deaths alone were attributed lo bacterial resistance to the medicines used to treat them. It has also been estimated that by 2050, more people could die from AMR than from cancer which is why il has been declared a global emergency. Common medical-associaled conditions that rely on anlimicrobial medicines lo work include, (not limited lo)- Cancer Surgical infections Urinary Tract Infections IUTII ThrLJsh loral and vaginal) Difficult births or neonatal health Sexually Iransmilled diseases le.g. Gonorrhoeal Organ transplants or prosthetic implants Malaria Dental infections HIVIAIDS Tuberculosis ITBI and other respiratory infections Foodborne illnesses or disease Rare diseases Immunocompromised patients Sepsis Non-communicable diseases le.g. diabetes)
The AMR Narrative Trustees, Report (continued) Year Ended 31 March 2024 Using a One Health approach AMR isn't just a human health issue., it affects animals, the environment, and, ultimately, everyone. In animal farming and food production, anlimicrobials are often used lo prevent or treat infections in animals. However, this practice can lead lo the development and spread of resistance germs in the animals and the surrounding environment. This can spread to humans in several ways-through direct contact with animals, eating contsminated meal or animal products, or through exposure lo contaminated soil and water. Antifungals as an example, play a critical role in both agriculture and human health, bul their use in food pr(Uction can contribute to the growing problem of AMR) in humans. This is why the "One Health" approach is so important to our charity. It recognises that the health of humans, animals, and the environment are all connected. and il stresses the need for a coordinated effort across these sectors to address AMR. Consumers, the public and others are equally impacted which is why they should be included. Founding Principles The AMR Narrative was founded by AMR patient survivor (Vanessa Carterl and seven founding trustees. Officially registered as a Charitable Incorporated Organisalion ICIOI on July 31, 2023, in the United Kingdom, it operates under ils constilulion. Vanessa's advocacy journey began after spending three years battling highly resistant infections following a car accident in South Africa in 2004 and an extensive len-year facial reconstruction. Her experience exposed critical gaps in medical systems, particularly in communication and policy, and highlighted a lack of advocacy from fellow patients, molivaling her to act. In 2013, she launched her advocacy efforts. Before relocating lo the UK in 2020, she envisioned a charity dedicated lo empowering others facing similar challenges with AMR. This vision was realised in 2022 with the estsblishment of the charity, aimed at amplifying the voices of those affected by antimicrobial resislance. Values We believe in upholding the highest values, because ultimately people's lives are at slake. We focus our work on seven values which include.. 1. Compassion 2. Empowerment 3. Collaboration 4. Integrity 5. Equality and Inclusion 6. Innovation 7. Sustainability Primary Pillars and Strategic Goals Considering rf(s charitable objectives, The AMR Narrative has defined its strategy around three clear strategic pillars. Although these pillars cul across 811 programmes of work, our activities can be calegorised according lo their alignment.. Developing Advocacy Capacity 2. Promoting Public Understanding 3. Fostering Global Community Risk Management A risk register has been created, and we plan lo monitor and review il annually, considering the growth of our charity and incoming revenue.
The AMR Narrative Trustees, Report (continued) Year Ended 31 March 2024 Volunt9ers and Extgrnal Advisory A voluntary treasurer was appointed outside of this financial year on the 8th of April 2024. Al present we do not have any further appointed volunteers, however, our exlemal advisory board do provide limited lime voluntarily on an ad hoc basis. Al present, we have 15 external advisors, 500/9 of which are made up of people with lived experience of AMR. Achievements, Performance and Major Activities During our initial 9 months as a registered CIO, we have carried out several activities in line with our strategic objectives on a limited budget and aim lo expand in the coming years. Webslte development Our website was developed in early 2022. In 2023, we expanded il to include.. A Blog: Designed to provide clear, concise articles that explain various aspects of AMR in plain language, catering to patients, the public, medical professionals, and others. Most articles are contributed by guest authors, including a general practitioner and an infectious disease expert. Each article is also reviewed by a patient and a trustee with scientific expertise. Topics we covered include.. 1. The Role of Diagnostics in AMR 2. Infection Prevention and AMR 3. AMR.. Not just bacterial infections. Let's talk about fungi. Newsletter sign-ups: A newsletter sign-up was added to our website, allowing users to stay updated on news about our charity. As our subscriber base grows, we plan to secure funding lo launch a quartedy newsleller. Al present we have 198 subscribers. Personal Stories Our website features a °Narratives Maller. section, showcasing personal stories from patients who have been affected by AMR infections. This section brings lo light the profound impact of AMR on individuals, lives, making this critical issue more relatable and accessible to a broader audience. It serves as a vital resource for patients, the public, medical professionals, researchers, and policymakers alike, fostering greater understanding and empathy across all sectors. Stories can be viewed here.. hll s'.Ilamrnarralive.or Inarralives-matterl A-Z of AMR (Directory) After securing our first round of funding in December 2023, we created an online medical directory. This resource offers accessible infomalion on various pathogens Igermsl and medical conditions linked lo AMR. While initial funding enabled us lo launch the directory with 10 entries, we plan lo expand it as an ongoing project to include many more. The directory is designed to provide patients, the public, medical professionals, and others with easy access to relevant information. Recognising that internel searches can often be overwhelming., we aim lo offer trustworthy and easy-to-understand resources that promote a clearer understanding of AMR and related topics. Al entries are written by medical professionals and moderated by a patient expert and an internal scientific advisor. In the coming years we also aim lo include entries submitted by trusted patient organisalions relevant to AMR.
The AMR Narrative Trustees, Report (continued) Year Ended 31 March 2024 Social media YouTube In 2023, we launched a YouTube channel showcasing videos and interviews led by a patient, engaging with fellow patients, healthcare professionals, policymakers, and patient organizalions. Our inaugural video featured 8 conversation between our founder, Vanessa, and the Chief Executive Officer of the UK Sepsis Trust. The video can be viewed at the following link: htt s."Il oulu.bel-M4Kv7vFnNI?si-YTIVe KTLaWOCU5. In 2024 we expanded our channel with further videos which we will add in our following report. Soclal Media Dlssemlnation This year, we also focused on building our online presence despite limited resources. During our first year, we successfully established our presence across FaboOk, Instsgram, X (formerly Twitter), and Linkedln. Community Dialogue on x.com (Previously Twitter) In partnership with the Centre for Disease Research and Policy ICIDRAPI, we co-hosted a series of dialogues on X which brought together various stakeholders, including patient representatives, medical professionals and others. The series ran throughout 2023 and hosted a total of twelve 1-hour sessions. Future Campaigns The AMR Narrative has identified a set of world health awareness days relevant lo AMR which il will utilise in upcoming campaigns on social media once we secure further funding. Public Relations Tradltlonal Medla During our first nine months, we were included in various mass media publications and events. some of these included.. The UK Telegraph (link} Metro Ilinkl Sun Newspaper Ilinkl BBC Radio Devon Ilinkl One Health in Action Initiative podcast Ilinkl Lotus FM South Africa (link} Evgnt Participation Events play a vital role in sharing our work with key stakeholders. Although limited funding allowed us lo allend only a few events this year, we are committed lo expanding our participation in the years to come. Some of the events we presented at included.. ReAct Global AMR Media Alliance IGAMAI AMR Inlervarsily Training Programme (Nigerial Ducil Blue- Pan African Mentorship Programme webinar CDC Foundation IUSAI Wilton Park IA UK Foreign, Commonwealth and Development Office) WHO - Implementation of the pe0p1e-ntred framework for AMR DRASA webinar= Supergerms and the future of infection (Nigerial Cara Network Ilrelandl Anlibiolic Guardian Awards (Organised by the UK Health Security Agency- UKHSA} Sefako Makgalho Health Science Pharmaceutical Division.. medical sludenl lecture (South Africa)
The AMR Narrative Trustees, Report (continued) Year Ended 31 March 2024 University of Malts webinar.. Political advocacy and closing gaps in AMR knowledge Pfizer virtual café Ilrelandl.. Innovative approaches for AMR Iwebinarl WHO Task Force of AMR Survivors.. The Vol of AMR Survivors in advocacy {webinar) Confralernily of Patients in Kenya.. Iwebinarl British Society for Antimicrobial Chemotherapy {BSACI annual Spring Conference and AGM Malla University Ivirtuall WAAW symposium Partnerships Considering our goal to develop a global community, we have been working actively lo build meaningful partnerships with other patient organisalions, community leaders, academics and health aulhorilies. External work In October 2023, our founder was appointed Chair of the WHO Task Force on AMR Survivors, which unites 12 patients and carers with diverse lived experiences. This followed her three-year appoinlment12020-20231 on the WHO-STAG (Strategic Technical Advisory Group), during which she recommended the creation of a patient- focused working group within the WHO. She also advises the UK government as a lay member of the APRHAI (Advisory Committee on Anlimicrobial Prescribing, Resistance and Healthcare Associated Infection) ministerial committee. Flnanclal Revlew and Reserves Pollcy Flnanclal Revlew Income for the year amounted to £17.155. This was made up of grant income totslling £16,711 and speakerlappearance fees of £444. Expenditure for the year, including expenses incurred in relation to the registration and creation of the charity lolalled £5,171. This was made up of expenditure for charitable activities and fundraising events tolalling £405, £421 for insurance, and management, professional and administration fees of £4,345. A surplus of £11,984 was generated and reflects the closing funds of the charity. Reserves Policy Since this was our first year raising funds, we have yel to establish a reserves policy. However, we plan to develop one in Collaboration with our treasurer and accountants in the Coming financial years as our budgets become more defined. Statement of Trustees, Responsibilities The Trustees are responsible for preparing the Trustees, Report and the financial statements in accordance with applicable law and United Kingdom Accounting Standards (United Kingdom Generally Accepted Accounting Practice). The law applicable to charities in England and Wales requires the Trustees lo prepare financial statements for each financial year which give a true and fair view of the slate of affairs of the Charity and of the incoming resources and application of resources of the Charity for that period.
The AMR Narrative Trustees, Report (continued) Year Ended 31 March 2024 In preparing these financial statements, the Trustees are required to.. select suitable accounting policies and then apply them consislenlly., observe the methods and principles in the Charities SORP., make judgements and estimates that are reasonable and prudent., stste whether applicable accounting stsndards have been followed. subject to any material departures disclosed and explained in the financial statements., and prepare the financial ststemenls on the going concern basis unless it is inappropriate to presume that the Charity will continue in business. The Trustees are responsible for keeping proper accounting records that disclose with reasonable accuracy at any time the financial position of the Charity and enable them to ensure that the financial statements comply with the Charities Act 2011, the Charity (Accounts and Reports) Regulations and the provisions of the Trust Deed. They are also responsible for safeguarding the assets of the Charity and hence for taking reasonable steps for the prevention and detection of fraud and other irregularities. Signed on behalf of the Trustees on 27:01:2025.by'. Dr F Chiara Chairperson 04IN Name.. Dr A Brink Trustee
The AMR Narrative Chartered Accountant's Report Year Ended 31 March 2024 In order lo assist you to fulfil your duties under the Charities Act 2011, we have prepared for your approval the accounts of The AMR Narrative for the year ended 31 March 2024 as sel out on pages 11 to 14 from the charity's accounting records and from information and explanations you have given us. As a practising member firm of the Institute of Chartered Accountants in England and Wales {ICAEW). we are subject to ils ethical and other professional requirements which are detailed at htt ..Ilwww.icaew.comlenlmemberslre ulalions-slandards-and- uidancel. This report is made solely lo the Trustees of The AMR Narrative, as a body, in accordance with the tems of our engagement letter. Our work has been undertaken solely lo prepare for your approval the accounts of The AMR Narrative and slate those matters that we have agreed to slate to the Trustees of The AMR Narffitive, as a body, in this report in accordance with ICAEW Technical Release 07116 AAF. To the fullest exlenl permitted by law, we do not accept or assume responsibility to anyone other than The AMR Narrative as a body for our work or for this report. It is your duly to ensure that The AMR Narrative has kept adequate accounting records and to prepare ststulory accounts that give a true and fair view of the assets, liabilities, financial position and profit of requirement for the year. We have not been instructed to cary out an audit or a review of the accounts of The AMR Narrative. For this reason, we have not verified the accuracy or completeness of the accounting records or information and explanation you have given lo us and we do not, therefore, express any opinion on the statutory accounts. Francis Clark LLP Chartered Accountants Sigma House Oak View Close Edginswell Park Torquay TQ2 7FF 10
The AMR Narrative Statement of Financial Activities Year Ended 31 March 2024 Notes 2024 Income from: Grants Other income 16,711 444 17,155 Expenditure on: Charitable activities Charitable activities and fundraising events Insurance Management, professional and adminislralion fees 405 421 4,345 5,171 Not incomg1{gXPgndituro) 11,984 Reconciliation of funds Total funds brought foNard Total unrestricted funds carrled fonvard 11,984
The AMR Narrative Statement of Assets and Liabilities Year Ended 31 March 2024 Notes 2024 Current assets Cash and bank and in hand 16,981 16,981 Creditors: amounts falllng due wlthln on year Trade creditors Accruals Amounts Owed to Related Parties 452 1.200 3,345 Net current assets and total net assets 11,984 The funds of the Charity Unrestricted funds 11,984 These accounts have been prepared in accordance with the Financial Reporting Standards 102 Second Edition 2019. The notes on pages 7 10 8 form part of these accounts. Approved by the Trustees on 27 J@n.u.g.ry. 2.9.25 and signed on their behalf by. Dr F Chiara Chairperson Name.. Dr A Brink Trustee Ms V Carter Executive Director 12
The AMR Narrative Notes and Accounting Policies Year Ended 31 March 2024 General Infomiation The AMR Narrative is a registered charitable incorporated organisalion, registered under the number 1204055, and was established under a scheme of the Charity Commissioners dated 20 July 2023. Ils registered office and principal address is.. Suite 3f Peel House 30 The Downs Altrincham WA14 2PX 2. Accounting Policies al Basis of preparation and assessment of going concem The financial slalements have been prepared under the historical cost convention, with items recognised al cost or transaction value unless otherwise slated in the relevant nolelsl to these financial slatemenls. The financial slalements have been prepared in accordance with the Statement of Recommended Praclice"Accounling and Reporting by Charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ireland IFRS 102} Second Edition 2019 and the Charities Act 2011. The accounts have been presented in sterling and rounded to the nearest £. The trust conslilules a public benefit entity as defined by FRS 102. The Iruslees consider that there are no material uncertainties about the Charity's ability to continue as a going concern. The followng principal accounting policies have been applied. bl Income recognition All income is recognised On the charity has entiuemenl lo the income, there is sufficient certainly of receipt and so il is probable that the income will be received, and the amount of income receivable can be measured reliable. cl Expenditure recognition Liabilities are recognised as expenditure as s(x)n as there is a legal or constructive obligation commilling the Charity lo that expenditure, it is probable that settlement will be required, and the amount of the obligation can be measured reliably. All expenditure is accounted for on an accruals basis and includes irrecoverable VAT. All expenses including support costs and governance costs are allocated to charitsble activities. Costs of Charitable activities include costs incurred directly on achieving the objects of the Charity, and govemance costs. 13
The AMR Narrative Notes and Accounting Policies {continued) Year Ended 31 March 2024 3. Grant Income 2024 Biomerieux SA Grant 16,711 16,711 4. Other Income 2024 Wodd AMR Awareness Week Speaker Fee 444 444 5. Charltable actlvltles and fundralslng events 2024 Promotional video for educational grant Donation plafform subscription 363 42 405 Management and Administration 2024 Accountancy fees Professional fees Bank fees IT SofbNare and Website Maintenance Training costs 1,620 1,512 56 1,094 63 4,345 7. Staff Costs The charity did not employ any staff during the year. Twstges and Other Rolated Parties No Iruslee or connected persons have received any remuneration either directly or indirectly. The Founder of the Charity paid for expenses before the Charity was created, as well as during the period ended 31 March 2024, tolalling £2,545. These expenses, combined with the £800 of funds the Founder injected when the when the Charity bank account was opened, make up the £3,345 balance owed to the Founder al the year end. Included in the £2,545 of expenses t)orne personally by the Founder was £970 relating lo IT Software and Website Maintenance, £1,218 of Professional Fees in relation to the registration of the Charity, and £357 of other Professional Fees and Training Costs. 14