Trustees’ Annual Report for the period
From 26[th] April 2023 To 31[st] March 2024
Charity name: MEF2C Foundation
Charity registration number: 1202843
Objectives and Activities
The MEF2C Foundation was formed for the public benefit, to advance and relieve the needs of people with MEF2C gene associated conditions by funding research for medical therapies for the treatment of said gene associated conditions provided that the useful results of such research are disseminated to the public at large and the provision of grants for therapies, equipment or sensory activities that will improve quality of life.
During the stated period, the MEF2C foundation signed a contract with the Medical University of South Carolina to act as guarantor for a project, Pathways to Hope, that committed a lab and team to researching three possible treatment pathways to relieve, or possibly even reverse the impact of MEF2C Haploinsufficiency Syndrome on impacted patients. The total cost of the project is $500,000. The MEF2C Foundation will ultimately pay $163,696 towards the total cost, with the remainder having been supported by private donors directly to the university.
The trustees of the MEF2C foundation have complied with their duty to have due regard to the Charity Commission’s public benefit guidance when exercising any powers or duties to which the guidance is relevant,
Achievements and Performance
The MEF2C Foundation had a very successful first year due to the commitment and enthusiasm of the MEF2C supporters community, securing £269,587.90 in donations to support our missions of improving the quality of life for those impacted by MEF2C gene associated conditions. These donation enabled the support of the “Pathways to Hope” program in collaboration with the Medical University of South Carolina (MUSC). This project has already identified a promising candidate to progress to the next stage of development of a therapeutic. The outcome of the project, irrespective of successful treatment candidate, will be published and further understanding of MEF2C Haploinsufficiency Syndrome and new treatment possibilities in the Global research community.
Another condition of funding the project was to keep MEF2C impacted families updated with progress and two webinars have been delivered to Members of the MEF2C (MHS) parent support & chat group, a global group that represents a
growing population of MEF2C impacted patients. Transparency and communication with the patient population is of significant importance to Trustees of the MEF2C foundation and will continue to form a key component of any project that the charity supports in the future.
Financial Review
The MEF2C Foundation has had a successful first year, raising £270,743.96 through a combination of donations (£269,587.90) and product sales (£1,156.06). Running costs for the charity have been minimal at £3,842.93 and costs of goods sold of £1,026.91. Having acted as guarantor for the “Pathways to Hope” program with the Medical University of South Carolina, there was a liability of $163,696 (£129,476) remaining at the end of the financial year with sufficient cash within the charity to fulfil that obligation as it falls due during summer 2024. Closing profit of £136,398.12 leaves the Charity well positioned to start the new Financial year with funds available to support further projects to support the Charity’s stated purpose, the relieve the needs of those living with MEF2C associated conditions .
Due to limited running costs and the Trustees commitment to have sufficient funds in place to commit to further projects, we are confident that the Charity will continue as a Going Concern.
Structure, Governance and Management
The MEF2C foundation was established on 26[th] April 2023 as a CIO.
The Charity is governed by a Constitution and a Research Grant Framework that governs how Trustees assess any potential Research Grant before unanimously agreeing to commit Charity funds in support of said Grant.
The current Board of Trustees are the 5 Founding Members. A unanimous vote would be required from existing Trustees to allow appointment of a new Trustee. Any new Trustee appointed would be selected on the basis that they have requisite skills, knowledge and experience needed for the effective administration of the CIO (MEF2C Foundation).
The MEF2C Foundation has and will continue to partner sister Charities in other jurisdictions to ensure efficient use of resources and ensure a Global Solution to relieving the need of patients with MEF2C Associated Conditions. Any partnership is undertaken with the guiding principles of the MEF2C Foundation in place and does not impact upon the ability for MEF2C Foundation to act independently.
Reference and Administrative Details
MEF2C Foundation
Charity Number: 1202843
124 City Road, London EC1V 2NX
Names of Charity Trustees
James Kelly – Chair – Appointed 26/03/23 Helen Eaton – Treasurer – Appointed 26/03/23 Dawn Kelly – Appointed 26/03/23 Matthew Eaton – Appointed 26/03/23 Lorena Garcia Fernandez – Appointed 26/03/23 Declarations
The Trustees declare that they have approved the Trustees’ Report above
Signed on behalf of the charity’s Trustees
Helen Eaton
Helen Eaton Trustee Dated: 30/01/25
Charity registration number 1202843
MEF2C Foundation
ANNUAL REPORT AND UNAUDITED FINANCIAL STATEMENTS
FOR THE PERIOD ENDED 31 MARCH 2024
Doc ID: 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6
MEF2C Foundation
LEGAL AND ADMINISTRATIVE INFORMATION
TRUSTEES James Kelly Lorena Garcia Fernandez Dawn Kelly Helen Eaton Matthew Eaton Charity registration number 1202843 INDEPENDENT EXAMINER AND Ross Stokes FCA, ACCOUNTANT The Accounting Collective Studio 8, 229 Shoreditch High Street, London, E1 6PJ.
Doc ID: 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6
MEF2C Foundation
ANNUAL REPORT AND UNAUDITED FINANCIAL STATEMENTS
FOR THE PERIOD ENDED 31 MARCH 2024
CONTENTS
| Page | |
|---|---|
| Report of the trustees | 1 |
| Independent Examiners's Report | 2 |
| Statement of Financial Activities | 3 |
| Balance Sheet | 4 |
| Notes to the Accounts | 5-8 |
Doc ID: 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6
MEF2C Foundation
REPORT OF THE TRUSTEES
FOR THE PERIOD ENDED 31 MARCH 2024
The Trustees present their annual report and financial statements for the period ended 31 March 2024.
The financial statements have been prepared in accordance with the accounting policies set out in note 1 to the financial statements and comply with the charity's [governing document], the Companies Act 2006 and "Accounting and Reporting by Charities: Statement of Recommended Practice applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS102)" (effective 1 January 2019).
PRINCIPAL OBJECTIVES AND ACTIVITIES
The charity's objects are
The trustees have paid due regard to guidance issued by the Charity Commission in deciding what activities the charity should undertake.
ACHIEVMENTS AND PERFORMANCE
Financial review
Structure, governance and management
The trustees, who served during the year and up to the date of signature of the financial statements were:
James Kelly Lorena Garcia Fernandez Dawn Kelly Helen Eaton Matthew Eaton
The trustees report was approved by the Board of Trustees.
Helen Eaton - Trustee January 2025
Doc ID: 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6
MEF2C Foundation
INDEPENDENT EXAMINER'S REPORT TO THE TRUSTEES OF THE BIOGRAPHERS CLUB LIMITED
FOR THE PERIOD ENDED 31 MARCH 2024
I report to the Trustees on my examination of the financial statements of The Biographers Club Limited (the charity) for the period ended 31 March 2024.
Responsibilities and basis of report
As the Trustees of the the charity (and also its directors for the purposes of company law) you are responsible for the preparation of the financial statements in accordance with the requirements of the Companies Act 2006 (the 2006 Act).
Having satisfied myself that the financial statements of the charity are not required to be audited under Part 16 of the 2006 Act and are eligible for independent examination, I report in respect of my examination of the charity’s financial statements carried out under section 145 of the Charities Act 2011 (the 2011 Act). In carrying out my examination I have followed all the applicable Directions given by the Charity Commission under section 145(5)(b) of the 2011 Act.
Independent examiner's statement
I have completed my examination. I confirm that no material matters have come to my attention in connection with the examination giving me cause to believe that in any material respect:
-
accounting records were not kept in respect of the charity as required by section 386 of
-
the 2006 Act; or
-
the financial statements do not accord with those records; or
-
the financial statements do not comply with the applicable requirements of section 396 of the 2006 Ac other than any requirement that the accounts give a true and fair view which is not a matter considered as part of an independent examination, or
-
the financial statements have not been prepared in acccordance eith the methods and pricipals of the Statement of recommended Practice for accounting and reporting by charities applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and
-
Republic of Ireland (FRS 102).
I have no concerns and have come across no other matters in connection with the examination to which attention should be drawn in this report in order to enable a proper understanding of the financial statements to be reached.
Ross Stokes FCA January 2025
The Accounting Collective Studio 8, 229 Shoreditch High Street, London, E1 6PJ.
Doc ID: 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6
| 1202843 Period start date 26/04/2023 To Period end date 31/03/2024 MEF2C Foundation Annual accounts for the period |
1202843 Period start date 26/04/2023 To Period end date 31/03/2024 MEF2C Foundation Annual accounts for the period |
|
|---|---|---|
| Section A | Statement of financial activities | |
| Recommended categories by activity Guidance Notes Incoming resources (Note 3) Income and endowments from: Donations and legacies S01 Charitable activities S02 Other trading activities S03 Investments S04 Separate material item of income S05 Other S06 S07 Resources expended (Note 6) Expenditure on: Raising funds S08 Charitable activities S09 Separate material item of expense S10 Other S11 S12 S13 Net gains/(losses) on investments S14 S15 Extraordinary items S16 S17 S18 Other gains/(losses) S19 S20 Reconciliation of funds: S21 S22 1 Total Net movement in funds Total funds brought forward Total funds carried forward Total Net income/(expenditure) before investment gains/(losses) Net income/(expenditure) Transfers between funds Other recognised gains/(losses): Gains and losses on revaluation of fixed assets for the charity’s own use |
Unrestricted funds Restricted income funds Endowment funds Total funds Prior year funds £ £ £ £ £ F01 F02 F03 F04 F05 - - - - 269,588 - - 269,588 - 1,156 - - 1,156 - - - - - - - - - - - - - - - |
|
| 270,744 - - 270,744 - |
||
| 1,027 - - 1,027 - 131,966 - - 131,966 - - - - - - 1,353 - - 1,353 - |
||
| 134,346 - - 134,346 - |
||
| 136,398 - - 136,398 - |
||
| - - - - - |
||
| 136,398 - - 136,398 - |
||
| - - - - - - - - - - - - - - - - - - - - |
||
| 136,398 - - 136,398 - |
||
| - - - - - |
||
| 136,398 - - 136,398 - |
||
Doc ID: 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6
Section B Balance sheet
| Fixed assets Intangible assets (Note 15) Tangible assets (Note 14) Heritage assets (Note 16) Investments (Note 17) Total fixed assets Current assets Stocks (Note 18) Debtors (Note 19) Investments (Note 17.4) Cash at bank and in hand (Note 24) Total current assets Creditors: amounts falling due within one year (Note 20) Net current assets/(liabilities) Total assets less current liabilities Creditors: amounts falling due after one year (Note 20) Provisions for liabilities Total net assets or liabilities Funds of the Charity Endowment funds (Note 27) Restricted income funds (Note 27) Unrestricted funds Revaluation reserve Total funds Signed by one or two trustees on behalf of all the trustees |
Guidance Notes B01 B02 B03 B04 B05 B06 B07 B08 B09 B10 B11 B12 B13 B14 B15 B16 B17 B18 B19 B20 B21 |
Unrestricted funds £ F01 - - - - |
Restricted income funds £ F02 - - - - |
Endowment funds Total this year £ £ F03 F04 - - - - - - - - |
Total last year £ F05 - - - - - - - - - - - - - - - - - - - - Date of approval dd/mm/yyyy 30 / 01 / 2025 |
|---|---|---|---|---|---|
| - | - | - - |
|||
| - - - 265,874 |
- - - - |
- - - - - - - 265,874 |
|||
| 265,874 | - | - 265,874 |
|||
| 129,476 | - | - 129,476 | |||
| 136,398 | - | - 136,398 |
|||
| 136,398 | - | - 136,398 |
|||
| - - |
- - |
- - - - |
|||
| 136,398 | - | - 136,398 |
|||
| - 136,398 |
- | - - - 136,398 - |
|||
| 136,398 | - | - 136,398 |
|||
| Signature | Print Name Helen Eaton |
CC17a (Excel)
20/01/2025
7
Doc ID: 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6
Audit trail
Sign
For signing Title For signing.pdf File name Document ID 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6 Audit trail date format DD / MM / YYYY Status Signed
20 / 01 / 2025 Sent for signature to Helen Eaton 16:04:35 UTC+1 (helen.eaton@mef2cfoundation.com) and Ross Stokes (ross@theaccountingcollective.co.uk) from ross@theaccountingcollective.co.uk IP: 162.125.63.18 20 / 01 / 2025 Viewed by Ross Stokes (ross@theaccountingcollective.co.uk) 16:05:49 UTC+1 IP: 62.254.150.218 20 / 01 / 2025 Signed by Ross Stokes (ross@theaccountingcollective.co.uk) 16:06:01 UTC+1 IP: 62.254.150.218 21 / 01 / 2025 Viewed by Helen Eaton (helen.eaton@mef2cfoundation.com) 10:17:49 UTC+1 IP: 82.132.214.106 30 / 01 / 2025 Signed by Helen Eaton (helen.eaton@mef2cfoundation.com) 10:47:38 UTC+1 IP: 92.234.105.233 30 / 01 / 2025 The document has been completed. 10:47:38 UTC+1
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Charity registration number 1202843
MEF2C Foundation
ANNUAL REPORT AND UNAUDITED FINANCIAL STATEMENTS
FOR THE PERIOD ENDED 31 MARCH 2024
Doc ID: 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6
MEF2C Foundation
LEGAL AND ADMINISTRATIVE INFORMATION
TRUSTEES James Kelly Lorena Garcia Fernandez Dawn Kelly Helen Eaton Matthew Eaton Charity registration number 1202843 INDEPENDENT EXAMINER AND Ross Stokes FCA, ACCOUNTANT The Accounting Collective Studio 8, 229 Shoreditch High Street, London, E1 6PJ.
Doc ID: 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6
MEF2C Foundation
ANNUAL REPORT AND UNAUDITED FINANCIAL STATEMENTS
FOR THE PERIOD ENDED 31 MARCH 2024
CONTENTS
| Page | |
|---|---|
| Report of the trustees | 1 |
| Independent Examiners's Report | 2 |
| Statement of Financial Activities | 3 |
| Balance Sheet | 4 |
| Notes to the Accounts | 5-8 |
Doc ID: 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6
MEF2C Foundation
REPORT OF THE TRUSTEES
FOR THE PERIOD ENDED 31 MARCH 2024
The Trustees present their annual report and financial statements for the period ended 31 March 2024.
The financial statements have been prepared in accordance with the accounting policies set out in note 1 to the financial statements and comply with the charity's [governing document], the Companies Act 2006 and "Accounting and Reporting by Charities: Statement of Recommended Practice applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS102)" (effective 1 January 2019).
PRINCIPAL OBJECTIVES AND ACTIVITIES
The charity's objects are
The trustees have paid due regard to guidance issued by the Charity Commission in deciding what activities the charity should undertake.
ACHIEVMENTS AND PERFORMANCE
Financial review
Structure, governance and management
The trustees, who served during the year and up to the date of signature of the financial statements were:
James Kelly Lorena Garcia Fernandez Dawn Kelly Helen Eaton Matthew Eaton
The trustees report was approved by the Board of Trustees.
Helen Eaton - Trustee January 2025
Doc ID: 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6
MEF2C Foundation
INDEPENDENT EXAMINER'S REPORT TO THE TRUSTEES OF THE BIOGRAPHERS CLUB LIMITED
FOR THE PERIOD ENDED 31 MARCH 2024
I report to the Trustees on my examination of the financial statements of The Biographers Club Limited (the charity) for the period ended 31 March 2024.
Responsibilities and basis of report
As the Trustees of the the charity (and also its directors for the purposes of company law) you are responsible for the preparation of the financial statements in accordance with the requirements of the Companies Act 2006 (the 2006 Act).
Having satisfied myself that the financial statements of the charity are not required to be audited under Part 16 of the 2006 Act and are eligible for independent examination, I report in respect of my examination of the charity’s financial statements carried out under section 145 of the Charities Act 2011 (the 2011 Act). In carrying out my examination I have followed all the applicable Directions given by the Charity Commission under section 145(5)(b) of the 2011 Act.
Independent examiner's statement
I have completed my examination. I confirm that no material matters have come to my attention in connection with the examination giving me cause to believe that in any material respect:
-
accounting records were not kept in respect of the charity as required by section 386 of
-
the 2006 Act; or
-
the financial statements do not accord with those records; or
-
the financial statements do not comply with the applicable requirements of section 396 of the 2006 Ac other than any requirement that the accounts give a true and fair view which is not a matter considered as part of an independent examination, or
-
the financial statements have not been prepared in acccordance eith the methods and pricipals of the Statement of recommended Practice for accounting and reporting by charities applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and
-
Republic of Ireland (FRS 102).
I have no concerns and have come across no other matters in connection with the examination to which attention should be drawn in this report in order to enable a proper understanding of the financial statements to be reached.
Ross Stokes FCA January 2025
The Accounting Collective Studio 8, 229 Shoreditch High Street, London, E1 6PJ.
Doc ID: 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6
| 1202843 Period start date 26/04/2023 To Period end date 31/03/2024 MEF2C Foundation Annual accounts for the period |
1202843 Period start date 26/04/2023 To Period end date 31/03/2024 MEF2C Foundation Annual accounts for the period |
|
|---|---|---|
| Section A | Statement of financial activities | |
| Recommended categories by activity Guidance Notes Incoming resources (Note 3) Income and endowments from: Donations and legacies S01 Charitable activities S02 Other trading activities S03 Investments S04 Separate material item of income S05 Other S06 S07 Resources expended (Note 6) Expenditure on: Raising funds S08 Charitable activities S09 Separate material item of expense S10 Other S11 S12 S13 Net gains/(losses) on investments S14 S15 Extraordinary items S16 S17 S18 Other gains/(losses) S19 S20 Reconciliation of funds: S21 S22 1 Total Net movement in funds Total funds brought forward Total funds carried forward Total Net income/(expenditure) before investment gains/(losses) Net income/(expenditure) Transfers between funds Other recognised gains/(losses): Gains and losses on revaluation of fixed assets for the charity’s own use |
Unrestricted funds Restricted income funds Endowment funds Total funds Prior year funds £ £ £ £ £ F01 F02 F03 F04 F05 - - - - 269,588 - - 269,588 - 1,156 - - 1,156 - - - - - - - - - - - - - - - |
|
| 270,744 - - 270,744 - |
||
| 1,027 - - 1,027 - 131,966 - - 131,966 - - - - - - 1,353 - - 1,353 - |
||
| 134,346 - - 134,346 - |
||
| 136,398 - - 136,398 - |
||
| - - - - - |
||
| 136,398 - - 136,398 - |
||
| - - - - - - - - - - - - - - - - - - - - |
||
| 136,398 - - 136,398 - |
||
| - - - - - |
||
| 136,398 - - 136,398 - |
||
Doc ID: 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6
Section B Balance sheet
| Fixed assets Intangible assets (Note 15) Tangible assets (Note 14) Heritage assets (Note 16) Investments (Note 17) Total fixed assets Current assets Stocks (Note 18) Debtors (Note 19) Investments (Note 17.4) Cash at bank and in hand (Note 24) Total current assets Creditors: amounts falling due within one year (Note 20) Net current assets/(liabilities) Total assets less current liabilities Creditors: amounts falling due after one year (Note 20) Provisions for liabilities Total net assets or liabilities Funds of the Charity Endowment funds (Note 27) Restricted income funds (Note 27) Unrestricted funds Revaluation reserve Total funds Signed by one or two trustees on behalf of all the trustees |
Guidance Notes B01 B02 B03 B04 B05 B06 B07 B08 B09 B10 B11 B12 B13 B14 B15 B16 B17 B18 B19 B20 B21 |
Unrestricted funds £ F01 - - - - |
Restricted income funds £ F02 - - - - |
Endowment funds Total this year £ £ F03 F04 - - - - - - - - |
Total last year £ F05 - - - - - - - - - - - - - - - - - - - - Date of approval dd/mm/yyyy 30 / 01 / 2025 |
|---|---|---|---|---|---|
| - | - | - - |
|||
| - - - 265,874 |
- - - - |
- - - - - - - 265,874 |
|||
| 265,874 | - | - 265,874 |
|||
| 129,476 | - | - 129,476 | |||
| 136,398 | - | - 136,398 |
|||
| 136,398 | - | - 136,398 |
|||
| - - |
- - |
- - - - |
|||
| 136,398 | - | - 136,398 |
|||
| - 136,398 |
- | - - - 136,398 - |
|||
| 136,398 | - | - 136,398 |
|||
| Signature | Print Name Helen Eaton |
CC17a (Excel)
20/01/2025
7
Doc ID: 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6
Audit trail
Sign
For signing Title For signing.pdf File name Document ID 568e1edc9ddd90ab7cda8bf8ac3aa5f92fe384d6 Audit trail date format DD / MM / YYYY Status Signed
20 / 01 / 2025 Sent for signature to Helen Eaton 16:04:35 UTC+1 (helen.eaton@mef2cfoundation.com) and Ross Stokes (ross@theaccountingcollective.co.uk) from ross@theaccountingcollective.co.uk IP: 162.125.63.18 20 / 01 / 2025 Viewed by Ross Stokes (ross@theaccountingcollective.co.uk) 16:05:49 UTC+1 IP: 62.254.150.218 20 / 01 / 2025 Signed by Ross Stokes (ross@theaccountingcollective.co.uk) 16:06:01 UTC+1 IP: 62.254.150.218 21 / 01 / 2025 Viewed by Helen Eaton (helen.eaton@mef2cfoundation.com) 10:17:49 UTC+1 IP: 82.132.214.106 30 / 01 / 2025 Signed by Helen Eaton (helen.eaton@mef2cfoundation.com) 10:47:38 UTC+1 IP: 92.234.105.233 30 / 01 / 2025 The document has been completed. 10:47:38 UTC+1
Sign
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