SPENCER DAYMAFI MENINGMSRESEARCH FOR THEYEARENIXNG (harltyNumber% 120#02 EY*land •nd W41
SPENCER DAYMA14 MENINGMS AÈSFARCH INDEX General IAform•¥on TNstees ReFort Trustees Re5ponsibilitie5 li Independ•nt Examlner5 Rèport Statementof HnOItlIeS Balance Sheet 14 Statomentof Cash Hows Notisto th Actour 16
SpENRDAymAN MENINGms RE5EAROt 6ENERAL INFCWIKf4 tharttyNumber. 1202Z02 ond SC052732 Trpe of Charfty: Charitsbk IncorForaied OT8anlsètion Prfnupal & Rqtsteredofftc•address Homeside Old Gloucester Road ston Br15tol B535 3LQ toulse Graham-chalr Stephen Gazard Stsphen S Dayrnan Jnr Quentin Stott Davld Bker Prlndpal Olfic•r Dr Steve Dayrnèn MBE (Founder) 5d•rtlfkM•dk•l Ad%4sory P•n Professor Paul Langford BSC PhD CO101 FR5B Professor Ray Borrow PhD MRCPath Dr Carollne Vlpond Professor Saul Faust FRCPCH PhD 08E I1ependent Exarnlner M3tthew Dobblns FCA Dunklelschartered Certif*d A¢u)untants Wt)odl&nLls Gr8n8e Woodlands lane Bradleystoke 8rlstol BS32 4JY Bank Lloyds Bank PO Box IOCK) Andover BXI IL
TheTTUStee5 prentthe1rTep0rttotherlththe finamtal statdnents fortheyearendlr¥31 Marth 2026. IntdUctiOn fromthg Chiir We a dellghted to preserrttoyou the 2026 Report and Accountsfor sor Dayman Meningrtis Resezrch, which showcasesour£hariWs progressand hIevements OUr3¥dn3ndI year 202S. 2026 Th15 year has been one otsl8nWkant wogre55 byexceedlTre JrfinèaI tsrgetsLV aga>Th. We ar proud that thlsvoluntsry charty wlth no paid staff 15 IlId11¥ noteworthy momentum.Throu8h thts yearfssucce55fvIfvndralsln8 endeavours we have be att0 s18nifafttty exp•nd our preventatfve research porrfdlo wh6ch now ude$ 3 preven1ate re5earth projects 18 undèrtaken * the Spencer Dayman Meninkitts Labortorle4 Btistol V&drtè Cntre, unertyof Brtstol. We extend our 8ratknde to oursclentlfic Medi¢al Ad41sory Panel forthelr8eneral •fvlce and guldance, 8lvln8th¢lrtlme to evaluate and rnonltor our research proFects. flerv)wned lorthelr knowledBe and experfene¢ In Inféttlous dISe& thelrvast understandin8 in thr re5pectivelleld$ 5 lthvalu¥b1o to US ond enyjrtsthls charlty funds felevant, meaniWI FYeveThts resoarth )f the hldhest qualty. Thls $ub$t•ntlil ad¥anrern¢nt would not have been èchlwed wlthout the coDtinucd dedlutlon and rtwavering commthentof oursUppters, volunteews and tntstees and we ar? proud to share thls achlevement wtththem, so many of Whom are famllles who have been affected by menlngttls and nlhprasqnrlatprt Ill349£ ThpfinanrL•l siipDtsrt(>lgrAIII FDuThlatlons. communlty or8anlsatbns, companle5 and Indfvidualsw35 trutyapwedated. The drIn&forCe behlnd ourchartty15 thè heartreaking realltythai hKldence of menln8ltls has Corrtinued to following the low nuMr of rKtrfficatlons durfTh8 the Covld pérkd aad that thro arestlll rnarry Infethonsthat causè meThin8ltis alldothEr a550ciatEd dlseasesthat are notvacclne preventable. Sadly. menln&ococl meolnglils wasln the in Marth 2026 th an outbreak In Kent domlnln8the headllnes whkh rèsuked kn 2 dths aNJ 20 confimied case5 of8roup 8 menlngocotcal disease. Th15 5ubstsntlates rhe wntlnuln8 ImportarKeof ouvvitsl worl tolund pre¥entafve researth, Improve dl>6nosis Into meThln8hk%, sepsi$ aftd othera%od•ted dlsease5. SUPrtIaMi11eS affectEd and raL%e awaren¢s5 Te8ardlng the 48n5ar*J symp Louis• Graham
SpENR DAYMAN MENINGm5 RESEAROI TRUSTEES'ANNUAL REPORT FOR 7HE YEAR ENIXNG 31 MAR012D26 Spencer Trdyman Menlw81tiS Researth was re8lsteredwrth the CharitythnYnbg00 forEnWand and Waleson 6 March 2023, and wtththeoffice of the kntti5h (hawity Re8ulatoroTh7Au8t 2023. fhÈ objeds ofthe charltyare.. I. To 3cfvants the eduotlcn of the publk In £enetal Iw)d pardcuknrty scientists) in the preventlon and tr&ment 0fmening$ and Other a5500ated dse5bY prtsffth( and funding resÈaith for the public benefft In all aspects of that subject and to putlL%h the usefitl results. 2. Forthe publlc benett to Wellthe needsof tkne affected by Menand otherassodated d15ease5. and theirfamllles ty meansotr. a. the provi5fon of peer-to-peersupport and practlcal 8thice.' . ral$ing publlc awar¢ness. The Trustees confinn thattlw have h)d reR•rd to pybll¢ benefft gulthce publLshed by the Charfty Cdmmlsslon In deternlTrln8the actlvw undortakert bythe CrIty. The chartry does not emplry any5tsff and rn11 QrelY9n volunteer4 Indudln8oui Prfnrlp¥l offlr. Dr Steve DayThan MBE who aLw prrylldesthe ofts, rnte4 heat and light•t notharye tothe charfty. Achlw•m•nts •nd P•rfttmc The charltyWè5 reg15tered on 6 Marth 2023tosupp)rt preventatfve 5denfft yesearth Into menln8itis and other asSlad dlsease5t prtsvidè peer support to Famil$ afferted bythese Iseases and ra15e awamess regardlw ImFxtèe ofrewislryth•sl8ro ondsymptoms of menln8ltS5 and other asso¢lated diases. The charlty's web51te {VfflNT4P¢tK•rd•yMxthenlr4llkreffjl our Importantwork Sncludln8 pfo¥ldln8 dlseasehcts. We are also aCtb onsoclal medla prm51nddlng F8b00 Instagra5ll 4nd Llnkedln. The tharitV$ prlftflpalalm ts to finantial YJPkKVt pTw•Thtatl%•re587rth * thèSp•ncer O•ym•Th man1$ L•bor•t¢rl•s. Brlrtolvatdm Centre. Unl¥wsltyot BrLstol. PresS contlnues globalty fe8ardlthedeYetOfitof safe and Effectfve ¥tbith SpenceT Oawnan Menin8itis r(esearch Whokheartedtysupkm). The Te5earther5 atthe Univer5iryof Bristol hève wortdrfenowned reputatrsns and have ted InvestigatOT5from around world. The5ewsit5 enhan¢ethe global sti¥rtificknowled8e of menlngltls and thherak4odatÈd dlsea
SPEIKEA OAYMAN 141ENINGmS RESEAACH TRLisfEEYANP4LIALIIEPORT Spencer Dayman men1ryt Resear5 preveTrta¢fvefe5eartfi wwtfulbls1Hed Grfj ASlr•ptocry¢w16LS) or%tr•pA' l$eStiMatedth3I GAS rawsowhalf a million death5 each YearWorl(lde. tnany of whom are chibjren. The diseases Caed byGASha¥e been increaslng ln recentyears, despite the avaiiabilityof antilyoticstotleatthese Irrfertions. GAS bartwia are USualtnSlIted through the throal mouth and nose. vacdnewhlch¢ould pre¥entGLSfrom infeclw¥thethrnaL mouth and wou5d greadyiedute thelmpa¢t of 6ASélsea5es. It Is one of the maln causes of sepsis and a wldewarlety of severe Invaslve" Infections such as the brain Imenlngitlsl, skin cellulitlsl. chest Ipneumonial, bones and lolnts. larthrtti¢ P5isl and heart disease (rheumatic fever). Thert ts novaccine avallable for GNS¥ThlltlSdeafwh1th parnsof the barterfa Icalled 8ntigen51 to Include In a ¥ac¢lne. Avlator Group Astrep IGASI Study. ThlsstsJ(tywhl¢hcrMnme¢)ced In O¢wber 2011 has made $18nlflcant pro8Tess whlch has inspired the In?StigatorS In the Spenw Dayrnan Re5éarth Laèoratorlesat the UnersOf Brlstol to $uc¢essfvltyapplyforanotheT 2 year5 fvndlng. The prole¢twlll rW£onl1DuI untll tober 2W47.The rexarch 8rowin8 ¢dLsfr0rn tonsllsof patlents which were remowd durlng rOfie surgery.To doth15theteam wlll separatèout the celLs 4ndthen 8rowthe celts In the laboratory alon8slde dlfferent parts of the GAS bacterla.Theywbll then mèasure thè Imrnunè PonSe of the tonsil 1]sfrOM dlffefent donor5 to help them make dedslons on whlch parts of the bactsriacould be ts)cluded In a swcessfvl vacclne. L•ad 18$ts1OrthlS re¢th projett arè.. Dr Anu Goenka-alnlcal LeLturer& H¢IrKrarycUtsnt Paedkitrfc lrnmunoloBY & Inf•ctlous dlseases Dr Alice Halllday- Letturerln Infe¢Elous Dseases Prof Daryl Klll- Profe5sorln Infettlous D15ease5 Dulln8 the year underrevlew Drfjoenka presented hls research atthe EUmas0dety0f Paedlatrlc Infectlous DLseases IESPIDI Conference Injune 2025 &The UK PaediatrirVacdnEGroup IUKPVGI annual meetlT¥ In Dttember2(FJ5. fjold b1onanownlurtateslgri rapld detettlon ol bxterla gep515, mon15 arKI other Telatlngi4sea5e& Thi58roundbreaknrq projert ha5 been extended to O¢tober 2026. ainsto provide evldenceto develop a r8iMd diagnostic tetttodetetta rary of berial disease In¢ludlng m1¥$ In 5 mlnutes. Early onsetof rnenln8Jt15 and sepsls Isvery dlfflcult t¢ detect and delty In mÈdlcal treatment can often be ¢atagtrophK. In ordèr to infomi the most Importsnt type oftreatrnerrt. itls e55enti31 to identify if the infe£tbn i5ous¢d by bacterlaora VIsand wuficaltywhlch barteria. At present, Identffklon can Stow, inaccvrateandoften teatht)gto death and dlsablllty. The Introdurtion of a rapNd dia8nosttc kit hasthe fftntialtsbe fo15ed outtsotonly in hospital enwro#ments also heath ntre$ and GP surgerle& ieed 5cientlsts fDrthL5 prolectarE- Prof Darryl Hlll-Profes50r In Infeciious Di50a$85 Drsean Davis-SeNor Lecturer
SpENR DAYMAN MENINGMSRSEARQI TRU5TEES'AN14UALREPORT FOR THE YEAR EPIDING 31 PAARCH 2026 anuscripts are cUrrentU[KIer rkn. before sukniwontrWir3tion. Diagnostlc EatIon o¢Taryt•d PCRfor EaItyC4Xffi of GroupAStreptocow IOETEcn The DECT study to start September 2026 will de¥ek)p a new bhJ)dtest U5ingadvanc molecular tethTh)to Idenilfy IrNasiveGroup AStrePtococcal liGASI batteria eadler and rre rellèbly. Faster ¢lagnosiswill lelp dottors5tsrtthe r¥httrtratnI scther. Improve survlval, OpmISe antlblotlc use and Tedu¢e stuftywlllaFso devel(Ip nEW Wavsto read the batterla's geThetlc code dlrecty frorn bk sample5. eTwbl1 l-tIMetraCkIry of outhre8ksand how the bacterla 15 eV01n8. DETEwIll SIARthe thild health resert tmprtsve thnt outcomes and supwrt better plannlngforfuture vacune Lead scient15t5 forthi5 prolett A.. Dr Conor 0'DonoVa NIHRAc4domlcalnkal Foll¢ & SpttlaltyTrainee In Paedlatrlcs DrAnu Goenkn- SenlLY Lecwrer & HonoraryConsull¥rtln Paedlatwk Immunoknand Infert5 D15eases tK Allce Halllday- Lecturer ID Irrfectbw D55ea5e& We take 8reat de In ensurfng that the preventativere5earth we fund Isof thÈ hl8hest quallty wlth the reassunncegf our emlnertklentilk M•diul Ad¥lsory Panel to gjperyise ihe pe¢r ¢evlew process. The chaiity promotes awarenessottht Importantsw and syMptonof menln81th and other assoclated d15ea5e5 cfj lt5web5ftetogetrwlth otherd5se#se 1nf0miatn. Many larnlltes wh¢ have experlenced the traumi that menlnRItIS and other assodated dlsease cause share thr seSon our new$ pi8esto help ralse awarene5S. Dlsease avA nets Is atso promoted throu8h so¢lal medla plorforms. News iterns reats0 dlstrlbuted to the prlnt medts naEioTwlty. Symptom cards and leafiets a distrlknd byvolunttèrs to variou5 lotations local io where ty lfve. Injanuorythe tharty pu)Alshed a new ieaftet forthe 8enwa5 publlc fe8ardlNq IMrtant Inlorynatlon atjout InvasN GroupAStreptococ¢•l dS¥ease. Ourfngthe yearfounder Drsteye Dayman sIted 22 famllle5who have expETterKed m¢nln8ltls and other a550claled diseases to prowde peer-tweer sur•(, andotherf8mille5 were suppDrted by phone and postal correspondence. Fundtalsln8Athkle5 Famllle5 that hove been affetted by TrInKtand other awdateddtseases conttnue to bean Insplradon io us zll. Fundratslrwwasorrd out by Srt0.Jn[eer$3nd membeT5 ofthe ganerdl puNlo Noextsrnal a8entsweTe used. Supporterfvndralsln8 included.. The annual Sam Memorial Walk and Famifv Fun1RnderS Dayln Gk)uceSrsh1re agal ex¢Eeded over f3,IKMI. CUraine Ru8by Club£3,C¥XI, In merrnryofcarl Mortelth.
SPENCEA DAYMAN MENINGMS RESEARC The George ZoBraphou memortsl foothall matth in Bristol Waed £l,gJ). The Geor8e Moore mernorièl bowJ5 m3tth In PrESt[raISed£?33.cI. The Partridge Pub In WatF¢rd, ouii rd £485.CK) In memory DfJa50n Murrov. PhoeniK Sport5 Cue aub. E&swod, Notts Ta15ed £IAhJ) in memory Dfjorthn BarbeT. Nemlle Green'sannual goEf in memoryof hig nR(eAleY2¢Klro ralsed £830.. exaer Fox ond hls frfendcaroline Eckhardt ra15ed £967 ruhnltva the AJ Bell Gli$8ow HI Marathon In memory of Arenderf5s&trrUara. Ethrti Ce Fund £2,(1)O Th15 yearthe dwrttyWagsJc(e551 In securfng5oI after pthln the London Vltallty IOL September 2025 and the London Marnthon andthe London i•rtdm•Fks Hllf M•rnthon in April 2026. These events ha¥e ralsed slBnlfkantfunds in thefinarKlal year. Manyofoursupporters andtrustees made pet%mal donatiow wjth lOn$ throu8hout the country or have tsken on Iheir own lundra1nl Gronts from charltabletrusts wnd foundatrorjs ¥MsthechartslaT8eSr irKome5tream. OurslrKere thantrs 80 to thefdfowlngch•A¢•bleor8anlsatlons wh05uprtedthecharfty wlth 518n1cant gifts thls year includln8'. Staflord Trust, Felt< Sh•w FoundatlDTr, SamphlreTnrtSabman Foundatlon. Ulzabeth Way Charltsble TrusL N DruckerCharitablèTru5¢ Bryan Gulnne55 CharftsbSeTrusL The Pbllanthroplst. Sto¢Weyiaiffe Charftab5e Trus¢ StrxlwelVCITffe charitrble Tfttst, Oakdale TWSL Aorents Shutt, J and M Britton Char1tabTnl Slr stsel Scott ofyews AnnettTrusL Mithael WatsonTrnsi, Genw5 Le8acy,XCZTrusL The Lo¢kettTru Flninclal Poslllon Ourlngtheyear the charity ralsed £181,844. EKpendlture was £95.048. OurprudenE nagement of funds dofied byoursupporters kept ourfvndratsingwenditure tolurt r£ofj8 forèvery£l Tal. Ourwrpluswas £86.796 and at 31 Marth 2026. we have £73,959 In restrfjcted funds, £16924 In de4snated funds (the amount ¢ommllt•d b4rt not covered by restrlcted funds èt31 Marth 20261, and E23,960 In OUT unrestrkted fvnd. Cash held on 31 March 2026wasÉ268.197. Full detalls of both Incorne and Expen&rtUTe (an befound In the rthaccompanylng the Acwunt The trustte$aresathfied the ch•rityts a 8tyn8 ¢<eM aThlfftfor PUTwse. lftthetrusfre'5 vlew, the reseNes should Fmide the chaFityW((h 3qte firwnclal stabllltyandthe means for Itto meet Its charitsble oblectlvesfor the foreseeable future. Wth no paid staff orpMIs the trustees alm to hold sufflclent fvntls to meet it5 primary expendTture commltmentsvthlch15 its research bJndlnB. At 31March 2026 a furthef £128I74 wa5 required tofvlTrlthe2 yearofthe oFfEwo]eCt (approved in Ortober 2025to start in September 2026 for 2yeatsl. Thtrustees are conNdentthat thi5 shortf311 w111 be rnised durtngthe Z02fv2027 a¢ti yeai.
SPENCER DAYMAN MÉNINGtns RESEAIQI TRUSTEES, ANNiIALREPORT The Trustees reYiewre5er¥ES re8ularty. Free reser¥es are unrestrftted fvnds dUd[S deslgnthd funds.Thetsrget forfree reserve5 15 to hold approxim•tety 12 monthsof annLthI COstsexdl1ng researchto enable the charityto ensure continuty in rts Sur¢ awaTrrse5s and fundraing aaivlty. As èt 31 Mah 2026. free reserve5 Ere£23960. As al31 Mirch 2026. all the ftjnds requlred forthe Temalnderofthe A¥lathrafvl Gold research projects are held in restrlcted ard dewated frJrKJs. AndthE tostof thefirst year of the new DETECT research Project Is ako hetd In dÉsl8nated luNls. Totsl re5tr¥rted resew at 31 March 2026 ère É73,959,Sesl8nated reseT¥tsare £169,024and Unf rp¥effts are Q3.W. Strurture, G¢wern4nce and Tr4M•nt Spencer Dayman Met)InAIt& Reseèrth lsavoluntary thartty7Mth no pad Staff. based In Aeston, BrLstol. The Chartty was re8lstered whh the CharltyCommlon on 6th March 2023 and wlth the Scottlsh Regulator IOSCRI on 7th Awu5t 2023.The ¢harity ts coritrolleil by it5governln8dowm¢nt'. Constltutlon of a Charl1ab Incorporated Or8arslsatkn iaoi. The strateglc dlrettlon of the ch3rlty15 determlned bythe Board of Trustee5 Irr consultatlon wlth the Ptlncipal 0fr, Dr Steve Dayman. The TN5tces m¢•t•t least4kniesa ye•rtoengJrttffeth 80Vern and 18oln5t bud6ets. A system of delegatkn Is In Pl aThJ day-ttrthy resFonslblltyfor the operatlon of the chèrfty restswlth the Prindpal Officer. Workln8d05ely wfth thè Board, the Prlndpal Offfcerls responslble f0rènsurtn8thattherk of ttch3rtty Fs camed out In Ilne wlth the strateglc dlrectlon deieymlned bythe Board olTrust The char¥ trustees are mindful of su1tsblysknl personsto Joln the Board and, thtnU8h thelr netwerks.they 8rew8trhful for entIal¢8nd1dateS. In a¢Wrd0n wlth the ¢horlVs iovemlw dMeNt. TTUSteesStephen D)ym8nJnr and Quentln Stott Ènded thetr3-yÈar tenure and offeved themse¢$ for re4edion. Try were formalty Te- elerted fora further3 ye•rs atthe Iru5tees Meengl Mrtl 2026. Ply and Expens spernr Oayrn¥n menINgLI Researth lsa¥ohrtarytharityWith no Nld stsff. AIthou8h theirustees tan clalm travel exp8nses. none were clalmed durin8the year. mIlath, the Sd2ntlfic Medlcal Atfvisory Panel were nol remuneTrted did they dalrn expen5e& Expenses weredaimed tyour Founder. Drsteve Dayman. and these are detalw In Note 7kntheActounts. Plangfor 202&2027 Spen¢er Dayman MeninBlts Resealthwill (Trttinue to wlowfjtse Its o)re mi55iDn of PreorIng menlngltis, sepsls and othera550¢iated dtaSL The new reHrth proied will commence in SÈptÈmbÈr2026. Buildine on thÈ pr(re55 of the last 3year%. durfnE thelattÈr part of the 2026- 2027 Nnanclalyear. In consultotlon wtththe chartys Sdentffic Medlcèl AsOry Panel, the trustees anticipate irwkiinB reseaTther5 atihe Bri5kn1 Vaiclne Centre, UnNersityDf Bristol, to appfOrgrat aldtQ5UPPQrtfurtherlnnovatlve preventative re5eafth into these di5ease5.
SPENCER DAYWIN MENINGtns RESEARCH FOR THE YEAR ENOING 31 MARCH 2026 The charFtywill akn continue to Tr15eawarene5satroutthese (knasesand provlde peer.tO-peer SUFVOrt and practlcal a(knto famllles affeaed. There a no plan5to ernpw paid staff and we 1[ tInuelore1¥ on ourvolunteers and 5UPPOrteTSto help usdeliver¢uiobiecb Rlsk Mana8eme The Tru5tee5 ?re aware of the requ1rementunderthestatent of Re£ommeTrded Practice 2019 to regularty assessoperatlng strengths. weakne55EsafKI rtsks. Thetrte¢S haye tyen conslderation to the major $k$the£haTtymty bÈ arKJ aresatlsfled th8iappropriate ntrS have been establishedto mana8ethose wk Publ1¢ Bgntffit l of the charws purpose5 and actmtles are forthe pubik benefiL Thetrusteesconfinn the tharlty h35 ccmplied wlth the dutyset out In Sectknn 17 of the tharities Art 2011 to havedue reRard to Public eenefit EuidarKe publlshed by the Charhycommlssion. The P1paI area of publK benefft 1$ the advancementof heakh and savlng lfv Fundralstni Stsndards Spencer DayThan MenlnEItL% Research Is reglstered wrth the Fund151 RegUtOr ID fiumber FR.ID- 274668.To datethe charfty has receed cOMplaInts about its fundrai51 è1tyitlossln¢e 1¢ was registered in March 2023. CompInts nd S1ld Durln8 the year under reewIhere were no comF4alnts orsafeguardln8 ts5uestoa&Jr 10
SPENCER DAYh1411 KNINGmsftÉsÉAR(H TRUSTEES, ANNUALREPOXT FOR THE YEAR ENDING31 MARCH 2026 The trustees of Spenr Dayman menin15 Re5earthare reS$1blet0r prep3rin8the Tru5tee5' Annual Report and the flnanclal statements in acCOrdar wlth oppltrknle kwand United ngdtsM Accourtting5tandard5 Iunited ngdoM Generalty Accepted Ac¢ountlng Practice). CharltyComrnb5KJn requlrpsthetru5teEsto prepare flnancial statements for eath finandalyeaT which give a true and falrwÈw ofthE 5tste ¢rfatrdi¥sdthe tharltyand of the ItKJ)mln8 resources and appllcatlon of resources Indudirb8 thÈ Income and expÈndittire, forth Year. In prepartn8 these financial ststements, thetruthes are requlredto: selectsUitae accoUnt5lde9 and then apptythem consbtsntly. obser¥e Ihe method5 wlndples In theCharlUesSORP: mèkelud8ernents and estimates that are reaTrae4nd Pfudent,. state whether op1£1ble UK Accountlry8Standards have been followed, yjblea to ary motet1al departtsw dlsclosed and explain in the fironoal statem•Ats,' ppare the flnandal statementsonthe 801r8c0nrn baslsvnless It 45 Inappr(wlaieto presume thatthe tharfty wlll contlnue In operntlon. The irustees ire respon$lbletor keep1 adequateac(¢Junt[ recordsthat dtsdose. wlth reasomble curacyl at arrytirne thefinan¢lal p051tlon of the tharlty and enable thern to enwre thatth¢ ITnandal 5tatem$nts coMplyw the Charrf(Its Act 2011,the Charlty (p£thwntsar Repertsl Re8ulatlons 2[ and the of constitlon. Try are alsoTe5ponsbi le forule8Uafdlni the assets of the charlty and hence fortsktw reasonae steps forthe prevention and detecuon ol frèud and other Irregulariti. Thls rert¥I ap1myed bythe Board on 26and signed on its behalf by LtyJlsGrahm ¢Ir
SPENCER DAYMAN MENINfjffS RESEARCH INDEPENDENf ExAmItILg RÉPIXT FOR THÉ YEAR ENDING 31 MARCH 2026 I reportto the tharitytrusteeson my examlnatlon of theaca)uDtsofthe tharftyfortheyeaT endEd 31 March 2026. Re%nsIbl ba%5 ofrepxt A5 the trustee5 of the chèrty you are rÈsponsibleforthe prepara1n d the acjrt5 in accordarKe wlth the requirements Oftchatte$3I1d TFYStee IrNestment (stIan) ALt 2LX15 (the'2(5 Ac¢l, the Charities Accounts (Scotlandl Regulatlon$ 2(lJ6 la53mendedl andthetharr(ie5Act 2011 Ilhe 2011 kv). You are 5atlsfled thatyour tharity Ls not rLyulrÈd bydwritylaw to beauditetl ar have ch03en Inmead to hwean Independéntèxamlnatlon. I report In respert ol my examlnaiion of thecharitys ac£ountsas carrled out undersecdon 44 Illlcl of the 2C(J5 Act and secllon 145 of ihe 2011 ACL In caThytn8OUtmyexamlnaiion I have followed the requlrements of Regulation 11 of theCharttlesAccOunts15coand1 Re8ulatlons 2(M)6 las amended) and the applirable Directions glyen bythe Charity Common und¥sectloTh 14515llbl 91 the 2011 Act. lttd•pqnd•N exgmlnerfs statem Slnce thetharny has pPared Sts accthjnts onan atcrua15 b35band Is also reg15tered In Swtldnd your examlner must be a mnberof a listed In Regulatlon IIIZI of the ChareSA(Unts Scotland) R•guiatlons 2fth l•s •mend¢dl. I corthnn th i am qualifiedto undertake the examlnatlon because l am a registered rrbemborof ICAEW whkh Is oneof ihe1151od bodle I have completed my e%aminaisori. I tonfirmthat nomatters hrneome to myattentlon glfi& me ¢au5e to bellevethat In any material respect.. l. accounYn8 rtto¢dswtré kept Ir• respectof the thartry oswulred tysectbn 44111 lal of the 2005 Act 3NJ Re8ulation4 of the ChaleS A¢o)untsl5¢oilandl Re8ulation$ 2W6 las amendedl and sectlon 130 01 the 2011 Ac(. or 2. the •¢¢ounts do nota¢¢ord wth those record5: f Ihe accwnts do notcomptywith the ac¢ountln8 wulrements ReBulation 8 of the Charttie$ Accounts IS¢otlandl Ae8ulatlons 2C*)61as amendedl and do not Comp ¥Ath the athlcable requlrements wncernin8 the fofm and content of a(unts Set in the Charitit5 (Accounts and Reports) Re8ulattons 28 olheT than any requirement thatthe accounts 8l¥e a'true andfaiivlew whlthls nota matter consIded as part of an Independent examlnaiion. I have rKb wncern5 and across no other m3tters lrttMnectton wlth the oxaminètion to which attention Should bedrawn in thts reportln orderto enable a prcper understandlng olthe accounis to be roacho Matthew Dobblns FCA Dunkws 0rtered Certllknl AcwuTrtants Woodlands GTrn8e Woodlands lane Bradleystoke Brlsthl ¥$3Z 4JY 12
SpENR DAYMAN MENINGMS RESEARCH srATEMENT OF FINA140ALAcnvmES {V4CWDINfj INCOME ANO EXPENDITURE ACCOUMn FOR THEYEAR ENDING 31 MARU120Z6 T+atal Funts ZOZ5 Fund¥ Intom• Donatlons Interest FundraisinKevents Total Incom• 70I75 177.764 119,111 898 iio 70.875 181 120,039 E%ndItr on: Generatlngfund5 Charltable actfvltles Research Svppert AwafÈness/Educatlon 14WI 14001 3.718 512 6360 3.958 69,417 69.929 6360 3,958 3087 4.961 3,463 Totsl •xp•ndttur• 2S.631 69.417 95.048 43M29 N•tln¢om• b•f(Ygknn¥fo 85338 L458 86.796 Transf•rs between fvnds Net movem•M ollundsln li 8I79G 76.9&1 Reconclllafjon of furmts.. Tor81 fund5 bfOU8ht forward Totslfunds ¢arrl¢d loryiard 107.646 n01 I,147 166,943 lQ3,167 180,147 li 192.984 73J59 The Ststement ol Flnanclal Indudesallplnsand1055e5 reco lnthe ¥eaT. All income and ¥pEndre derfVfrM contknuln8athlUts. 13
BALAN SHE ASAT31 MARCH 2026 Fund5 CurrentAwts Cash at bank 194.238 73J59 268,197 181,437 73.959 261197 181,437 Cr•dltors Amounts due wlthln one y¢4r li2) 11.2541 IL2901 N•tCUrrASS¢ 984 73.959 266.943 180.147 Tot•1 N•tAs#ts io 192,9B4 73,959 180,147 The Funds oltht crtty unretted 5n¢ome funds Des18nated fuThJs Restrfctéd lfftcorne funds 231 233&) 84.7S2 169.024 169,024 22,894 li 73?59 73.959 n,501 192,984 73959 266,943 IW,147 These have been prepBred In aCcordanwIth the prlnSPplIratsle to tharitabl¢ Incorpoffdted 0r8anlsat% These accounts were approved bythe 8oard ofTru5tee50n_. behav ol the board by: - 2026 aj are sl8ned on Loulse Groh&m Chalr 14
SpENR DAYPAIN MEPIIPIGMS RESEAROI 2025 Cash11ry5from opwotrfa¢tl¥ltieY. Net rtwvement in funds for the rekXtirYye¥las perthe statement offlnanclal actMtle51 86,796 76980 Adlustmentsfor De(aSe in debto 1ncreaselldecre} in creditor5 39J Netcash provlded by lused Inl operatln8 artwriS 86.7 77370 Ch Sn cash4nd c4th•gufv•lwtslnthe reptky 86,760 77.370 Cash and 4sh equl¥ntsatthe beqlnrlrryoftlr4wxtlryt IBL437 104,067 Cash oDd cth wulvalwts atthe axl ofthe ioportthy 268,197 181.437 l5
SpENR DAYMAN MENIN6ms RESEARCH P•)TESTOIHEACCOUNTS FCrfiTHEYEARENDING 31 MARCH ¥J26 L AuourrttryPolkle5 The folknwln8 accounting pdkies Iwve been ed mi51entty In thallrq items vknlth are consered materkl In relatk)n toihe thariivsactourrt l•) Basts of The financial #aTrments have beert prepa¥ed in accordan with Accounti and RÉptsrting by Charthe5'. Ststement of Recommended Practice applicable to tharftle5 preparin8 thelr accounts In accordin wlth the Flnanclal Rewrtlng Stsndard applcable In UX and Republic of Ireland IFRS 1021 leffettlve l January 20191- ICharllb¢s 50RP IFRS IOZII. Anala1 RekK¥1(rq staard 4pplScable inthe UK and Republic of Ireland IFRS 1021 and the Charltles Act 2011. Th¢ charltylsa wblk benrftenlSty. The fiTrandal statements hrn been wepaTed on a goln8" concern basi& The tnjrteesconstderthatthe thartty h)Ids suffkbent reserves toachlv4e an orderfy closure lTrth¢ unllkely event of a lOof fvrtdlng. The flnèndal statements a Pfesented in sterhn¥whlch ts thèknttknial ojrrentyofthècharlty and rounded ttrthe nearest£. ibl CoN•rn The contlnues to be a need for the charty. Wilh no pald Maff, the charws principal expendlture commitment Is research grant frIng. At thE yE¥r end. the charlty held $tr{rted and des18nated fund5 tomeetthe ¢uvrentEommltted stage5 oflts research projects, wllh afurther£128,874 Tequlrod to fund the second year of the DETECT prolert The tfustees are LY)nfident that thls shortfall will be ralsed durlngthe 2026-2027ar£ountin6yeaT. ThecharrtYa0holdsÉ23.lfi unrestrfrted r¥èrvÈ5. On th1$ basis, thetrustees arnsatbntd thattht dwlty Temaua 8oJty cortem. Icl Fund A¢counth Ilnre5tricted funds are Renpral bjnds that are avallable for use at the tru5tee5' dlscrntlon In fvrther•nce Ofthe objertfves of the chartty. DenatedIunds aret1 putaslde to be edfortheajmpletiOfi ofcurrent fewrch prohcts. Restrltted funds are those donated for use In a partlcular area or ksr spth purpose4 the ust of whlch Is restricred tothat area orpury)5•. Idl Incom• Incomefrom donationsi 8rants and contracts is rtto8ni5ed where there is entltlemenL probabilityof rèceipt and the amount can bè mèasured with suNldent relvab511ty. lthvstment irKoTh, tr11 incomÈand other incfjmeait rerw15ed on a receIvae ba*. 16
SPEPICER LvAW4 MENINGMS AÉSÈARCH NOIESTO THEACCOUPll5 lel Exwndtturn Expenditu reco8nised on 3n 2ccruaJs basb. ExpEndir& Indude5 aryvalue Added Ttx whlth Is reported as part of the expondituretowhith it relate& Expendlture on Reneratln8funds mmprises cost$3$SLètedWfth attraLttng Income. EXPenéftU on charhable arttrvitles cornprise5 those (osts incurred the thafity In the d@IlvÈry of its researth. peer surwrt and awarene55 raisin& It irtdudes both costs that ca be allocated direthy to eath of these and those costs ol an Indirect nature necessary to 5UPPOrtthem. SupportC05tsarealbrated betweentheexpenditurecategor(esofEheStatèmentof Finandal ACtIvrt on a basK% de5tgned to reflect the useof the resouT¢e. In Grnnts PbI Grants are awarded for research projects approved the Sctentlfic Paneland the Soard. These bettjme payable In attordance wlth researth ayeernents foreath prolecL PayrneThts are phased across the project and are éependerrt on progress belngmadÈ. Expendlture b Induded In the accounts as each payment bemme5due. 1¢) TtIon The charity15exempt from tsx on Income and gaila111¥Wtth1ftse¢t[0n 505 of th¢Tax•sArt 1988 orsectlon 252 oFtheTay2tlon of ChargeableG•buArt 1992tothe extentthatthese are appl to Its charltable object5. Ihl C•5h •t bank Cash at bank and In hand comprkes balartes held In current acrountsand notlcedèposR attounts. IIICredlto crditOrS recognlsedwhere the chartty has •n obllBatlon thatwlll result Inthetran5ferof funds tc a thlrd partyandthe amount due tosettletheoblls•tlon can be wswed orestlmated rellabty. l D•btors DÈbtOTS ère rewnlsed where there i$4n oblffjallonthatwlll rewltln thetransferof fvnd$tothe charlty and the amotsnt owlw can be measured Ik}SnllkintJud8ements and Esllmates There are no 51gnlfKarrtlud8ements or ertlmète5 requlred kn the pytwrntbn ofthese finandal statements. Z Incorne from Donatlon5 2026 Donatlofis Glft Ald Trusts & Grants L4acies Gfft5 In nd 68,723 68,723 33,53S 2,197 89375 72.015 16*86 10,146 1,218 70I7S 16W6 i(E889 70A75 177.764 119,111 17
SpENR DAYMAN MENIN6ms RE5EAKH NOIE5TOThEACCOUNTS FOR THE YEAR ENDING 31 MIACH 2026 3 ExpendEiure ontharttsble acthtii VolunieeT Expere5 }rTraVel Research Grdnts & Equipment Comms Ilncl PR & pried materiabl WeblDlgltal Postage & Ststionery Supwrt Costs INote4al Governan INote4al 4.5 3,988 69,417 30.233 1,449 1,480 922 730 1,803 862 1.036 368 1020 L650 69A17 1.449 922 I3 1.036 I,10 29 69A17 &).247 39.310 R#e•rth CommStm•nts Projert leld I Held In Fund$to bg 2026 •131 2026 60.24S 44,325 42,116 29.634 •131 Mar 2026 44.221 Aal¢r Gold D£rÉcr 148,791 71,598 253.677 124,803 J28,874 Total 4A An•hnli supPortIGa¥•C eogts 2026 Support Support ATrn•neM Totsl Fundrnthlr Clwritsblt 7ot41 2026 Iycosts Insurance $32 231 782 219 35 IM36 347 74 12 433 1.129 293 47 L469 73 12 Ico li 315 617 fjovernance R¢¥•r¢h Awrenes6 Totsl FundFald Charltsb]e Totsl 2026 Independent Exarnlr rofe¥$5on41 Advk• Tax Return Bankcharges 12 12 12 36 1.020 36 1.020 18
SPENCER DAYK4N fvENINGfr RESEAROI FOR ThEYEAR ENDING 31 MAROI 2026 Sb knolyslsolsupwl &Go¥*TnaM¢e Cosis2025 Support Resthrch Sypport Awaren Totsl LfvrftablÈ Total ITcosts Insurartc• 29 117 146 196 26 61 207 262 Ico 13 107 13 141 Tthl Futhlyln4 Totst 2025 Independent Emaminer Professlonal Advice Tax ReturTr 1.020 L020 120 120 320 270 270 550 550 550 1,650 6 Independent Examln•rfs RemerOn 2026 IndependEnf Examlnitson Ftts 1,020 There a no staff employed bythe charlty. p&)trustees hwe teen pald an¥ reMUneraOn or received any beTherfroM an employmertwithin the tharrty. 19
SPENCER DAYMAN MENINGMS RESEARUI IIOTESTO THEACCOUNTS FOR ThE YEAR ENDING YI MAROI 2026 8 Refatsd PartyTr3nsacUons No donations made ty relaied pt512025. £01 Expenses were P3Klto our Printhpal Offiw. DrSte tkyman MB&' Travel & Subststen¢e 5.878 1,104 307 4.3SS 151 241 Fundrolsl 5uppK)rt Costs Postage & 5tthonery Comms L406 63 120 9,617 6,256 No trustees had expen5e5 relmrSed. 9 Credltors-Amw)ts Falllng LknWSthln Oney 2026 2025 Ac£ru315 and othertredltors 1.254 1,254 L290 loa kn4W¥ofNetAssets b•twe¢n Qwrertyear2026 2026 Cash Cl1t0Ts le55than I year 194,238 IL2541 191984 73.959 268,197 11.2541 266,943 73.9 lQbAnalysh0lN Assets between Funds pr10$ Trr2025 1025 Cash Creditors knthan l year IrA,936 (l21) 107.646 72501 181,437 11,?.901 180.147 72SYI
FOR ThE YEAR EIIDIN6 31 MARCH 2026 11 M¢womentson Fund5 Balance 31M 2025 Curr•ntYe4r Balan¢• In¢ome Tr•nsf$ 3IM)r2026 A•strf¢thd Funds fteseah Totsi Restrktd Funds 72,501 70.B75 ?075 169,417) 169A171 73,959 Oe5iBnated Funds 146,ts0 169,024 Unrestrlcted Funds 84.752 P5.6311 146.130 23,960 Total Funth 266,941 Rtsearch Fund.. Funds recefved towardscuffent 5tlentlfi¢ restsrth proktt b•ln8 undertaken It Spencer Dayrnan iaboratoriésat BFtstd uner5ty. D85iznated Fund.. Funds requlred forthe cOmpth)n of Avlatyra Gokl re*arth prole¢ts. and for Ihe fir4 year of the DgfECf researth probecL 21