SPENCER DAYMAN MENINGITIS RESEARCH TRUSTEES ANNUAL REPORT AND RNAf+iaAL STATEMENTS FOR THE PERIOD ENDING 31 MARCH 202S Charity Numbers 1202202 England and Wales SC052732 Scotland
SPENCER DAYMAN MENINGtris RESEARCH INDEX Page General Informatlon Trustees Report Trustees Ae5ponslbllltles li Independent Examlners Report 12 Statement of Flnanclal Actlvltles 13 Balance Sheet 14 Statement of Cash Flows 15 Note5 to the Accounts 16
SPENCER DAYMAN MENINGITIS RESEARCH GENERAL INFORMATION Charity Number: 1202202 and SCO52732 Type of Charity. Charitable Incorporated Organlsation Prlnclpal & Reglstered offlce address Homeside Old Gloucester Road Alveston Brlstol BS35 3LQ Trustees Loulse Graham- Chalr Stephen Gazard Stephen S Dayman Jnr Quentin Stolt David Booker Principal Officer Dr Steve Dayman MBE (Founder) ientific Medical Advisory Panel Professor Paul Langford B5c PhD C101 FRSB Professor Ray Borrow PhD MRCPath Dr Carollne Vlpond Professor Saul Faust FRCPCH PhD OBE Professgr lan Fevers 85c, PhD AppDinted October 2024 Independent Examlner Mathew Dobbins FCA Dunkle5 Chartered Accotsntants Woodlands Grange Woodlands Lane Bradley Stoke Brlstol B532 4JY Bank Lloyds Bank PO Box 1000 Andover BXI IL
SPENCER DAYMAN MENINGITIS RESEARCH Trustees, annual report for the perlod endlng 31 March 2025 The Trustees present their report tOEether wlth the Ilnanclal statements forthe perlod ending 31 March 2025. Introduction from the Chair We are deli8hted to present to you the 2025 Report and Accounts for Spencer Oayman Meningitis Research, which showcase5 our charity's progress and 3chievement5 In our 2nd financial year 2024- 2025. The continued dedication of our supporters, volunteers and trustees resulted In exedIng our financial targets again and we are proud to share thls achievement wtth them, so many of whom are famllles who h3ve been affected by menlngitis and other associated dlseases. The financial support of grant giving Trusts and Foundations, community organisations. companles and indlviduals was twly appreciated. We also extend our gratitude to our Scientific Medical Advisory Panel for thelr general advio and guidance. giving thelr time to monltor our flrst preventatlve vaccine development research projeci entltled- Group A Strep Avlator Study which commenced in October 2023. In addition, they evaluated and approved our 2 preventative research study entitled: Gold blonanoconlugate5 for the ropid detection of barteria causlng sepsls and menlng5tls. This is a 12-month study to provide evidence to develop a diagnostic klt to detÈtt sepsls, meningitls and other associated diseases in five minutes. Thi5 Study commenced In November 2024. Thelr Invaluable support ensures thls charity funds relevant, meanin8fv1 preventadve research of the hlghest quality. Despite oursuccessful year, the heart-breaking reality remain5 that there are Still many infection5 that cause meningitis and other a55ociated diseases that are not vacclne preventable. Since the end of the Covid pandemic, we have seen a rise in the number of infectious disease5 Includlng meningitis and other associated infections. Thi5 confirms the continuin8 importance of OUT Vital worl to fund preventative research, improve diagnosis into meningit15, sepsis and other a550ciated diseases, support families affected and ralse awareness regardlng the sign5 and symptoms. Louise Graham
SPENCER DAYMAN MENINGtrs RESEARCH Trustees, annual report for period endi 31° March 2025 Objects Spencer Dayman Meningitis Research wa5 re8lStered with the Charity Commlsslon for Ett8land and Wales on 6 March 2023, and with the offi of the Scottish Charity Regulator on 7 August 2023. The objects of the charity are.. l. To advancè the educatlon of the publlc In general land partieularty amon8st scientists) in the preventlon and treatment of menlngitis and other associated diseases by promoting and fvndin8 research for the publlc beneflt in all aspects of that subject and to publlsh the useful results. 2. For the publlc benefft. to relieve the needs of those affected by meningitis and other assodated disease5, and thelr famllles by means ofr. . the provi51on of peer-trtrpeer support and practlcal advlce: b. ralslng publlc awareness. The Trustees conflm that they have had regard to publlc benefft guldance pub115hed by the Charity Commlsslon In determSnlnB the artfvitle5 undertaken by the charity. The charlty does not employ any rtaff and relles entlrely on volunteers. Includln8 our Prfnclpal Offlcer. Dr Steve Dayman MBE who also provides the offi, rates, heat and light at no charge to the charttv. Achlevements and Performance The charlty was re8lstered on 6th Marth 2023 to support preventatfve sdentiflc research into menlnBIt15 and other a5SOCiated diseases, provlde peer support to famllles affected by these dlseases and ralse awareness regarding the Importance of wognlslng the slgn$ and symptoms of menlngltls and other assoclated diseases. The charity's website IwwH.spencerdaymanmenln8ltlsresearth.orgl hlghllghts our Important work Includlng provldlng dlseases facts. We are grateful for the support of the Srarfish Trusr who contlnue to S[)n$01 the Maintenan of the web51te. We are also artfve on 50cial media platforms Including FacebooK Instagram and Ltnkedln. Supportlng prewntative research at the SpeDcer Dayman Men11t1$ L4boratorles, Brlstol Vaccine Centre, UnhISItyaI Brlrtol. Progress ¢ontlnues regarding the development of safe and effective vaccines which Spencer Dayman Menlnglt15 Research wholeheartedly Supports. We take great pride in ensuring that the PTeventative research we fund is of the highest quality. To achleve this, we rely on the expert15e of our eminent ScientTfic Medical Advisory Panel, nowned for their knowledge arHI experlence In infeCtU5 diseases. Their vast understanding in thelr respectrve field5 15 invaluable to us and we are 8rateful to them for 8ivin8 their time to support our work.
SPENCER DAYMAN MENINGMS RESEARCH Trustee< annual report for perfod ending 31° March 2025 Research Project: Aviator Group A5trep Vactine Study: October 2024-(kn**er 2027 Our flrst research proleffj Avlator Group A Study. commenced on 1st Qktober 2023. Group A Streptococcus IGAS) or"Strep A" 15 a bacterium which can cause a range of diseases from mild infections affecting the throat and skln to severe infertions including meningitis, pneumonia, rheumatic fever and sepsis. It is estimated that GAS causes over half a million deaths each year worldwde, many of whom a children. The diseases caused by GAS have been in(Teasin8 in recent year5. despTte the availablllty of antibiotics to treat these infertion5. GAS bacteria are u5u3Ity transmitted through thè throat, mouth and nose. A vaccine which could prevent GAS from Infecting the throat, mouth and n05e would greatly reduce the impact of GAS diseases. There is no vaccine available for GAS and it is unclear whlch parts of the bacteria Icalled antigens) to indude in a vaccine. Lead scientists for this researth project are: Dr Anu Goenka- ainlcal Lerturer & HOrrary Consultant in Paediatri¢ Immunology & Infectious diseases Dr Ajice Halliday- Lecturer in Infecttous Diseases Prof Darryl Hill- Professor in Infertious Diseases The team have developed an innovative approach that uses a new technique called tonsll organold model. Tonsils are part of the immune system which help us ffight infection. The research involves growin8 cells from tonsils of patients which WE removed during routlne surgery. To do this the team will separate out the ce115 and then grow the celb in the laboratory alongside different parts of the GAS bacterla. They wlll then measure the Immune response of the tonsil cells from dtfferent donors to help them make decisions on which parts of the GAS ba¢teria could be included in a successful vaccine. Due to new findings arhd after con5ult3tton with our Scientific Medical Advisory Panel, the researchers will apply to Spenr Dayman Meningitis Research in the spring of 2025 to extend the projert for a further two year5. Scientific rnerit perrnittir the extension wlll run to October 2027. The EKpetted outputs are: l. Peer-revlewed paper<sl within 2 years 2. Projert grant or fellowship award wfch industry partnership to utilise finding5 During the year, Dr Goenka presented his findings at Imperial College London and the UnNersity of Cardlff. wlth acknowledgements to Spencer Dayman Menin8itis Research. Research ProJecL' Gold bionanoconjiWe5 for the rapid detection of bacterla causlng sepsts and meninwt5s: NLwembèr 2024- ottober2025 Th15 12 Month project aims to provide the evidence to develop a diagnostic kit to diagnose meningili5, sepsts and other bacterial disease in rtve minutes.
SPENCER DAYMAN MENING]TIS RESEARCH Tru5tee5' annual report for period endln8 31" March 2025 Early onset of menlnglt15 and seps1515 very dlfficult to detert and delay In medlcal treatment can often be catastrophic. In order to inform the most important type of treatment, It is essential to Identify if the infectlon Ss caused by bacterla or a virus and speclfically whlch bacteria. At present, Identification can be slow. inaccurate and often leading to death and d15ablllty. The Introduction of a rapSd dlagnostic klt has the potential to be rolled out not only in h05pltal envSronments but also health centers and GP surgerles. It wlll also reduce the deaths from menlngltls and sepsls, and Ilfelon8 dlsabllltv. Lead sclentlsts for th15 proSect are.. Prof Darryl Hlll Professor In Infectious Diseases Dr Sean Davi5- Senior Lecturer Both the research teams have world-renowned reputatlons and have h05ted Investlgators from around the world. These vlslts enhance the global s¢lentlflc knowledge of menln8ltls and other assoclated dlsease5. Ra151nK Awarene55 and Peer-tO-Peer Swpport The charlty promotes awaTeness of the Important 518n5 and symptoms of menln8ltS5 and other assoclated dlseases on Its webslte together wlth other d15ease Informatlon. Many famllles who have exrenCed the trauma that menlngitis and other associated dlsease cause share thelr storie5 on our news pages to help ralse awareness. Dlsease awareness Is also promoted through soclal medla platform5. New5 Iterns were also dlstrlbuted to the prSnt medla natlonally. Symptom cards and leallets are dlstrlbuted by volunteer5 to varlous locations local to where they live. During the year founder Dr Steve Dayman visited 26 famllles who have experlenced menlngltls and other asso¢lated dlseases to provlde peer-to-peer support, and other famille5 were supported by phone. Fundra151n8 Artlvltles The driving force behind our fundralslnB actlvities are famille5 that have been affected by menlngltls and other assocSated diseases. Supporter fundraisin8 ha5 included: Sam Vlrgo Memorlal Walk and Famlly FunlRounder5 Day In GIOusterShIre ralslng over £3,000 Golf Days In Nottlngham organised by Colin Wa8ner and hi5 50n, Burt, In memory of Dylan Stott ralsing £2.100 Neville Green's Golf Day in Che5hunt In memory of hls nlece, Alexandra, ralsln8 £1,200 In Londonderry friends of Darren and Emma Cowie raised £1,100 from a sponsored football match
SPENCER DAYMAN MeNINGIT115 RESEARCH Trusteeg annual report for the period ending 31" March 2025 Family and Friends of Andrew and Elalne Zographou ralsed f2.450 In memory of thelr son George Donations in rnemory of Chris jackson raised over£2,Q Carys Brannan and her sister Lois donated £1.150 in memory of their mother Meg Lynne Dodgson donated £1,200 from her aborted trip to the Great Wall of Chlna In memory of her son Michael. Many of our supporters and trustees made personal donations, helped with collections throughout the country and taken on their own fundraising event. Grants from charitable trusts and foundations was the charit5 largest income stream. Our slncere thanks go to the following charltable organIsaonS who supported the charity this year. Florence Shute Millennium Trust. The Ardwick TrusL N Ducker Charitsble Trust, Starflsh Trust, The Dalglelsh Trust, Bacta Charitable Trus¢ de Laszlo Foundation, The Forrester Family Charitable Trust, The Thriplow Charitable Trust, The Chades and Elsie Sykes Trust, The Grace Trust, The Coreus Foundatlon, The Webb Family Charitable Trust. The Sylvla Altken Ch3rltable Trust, Thè Garfield Weston Foundation, HOH Wllls Charitsble Trust, Stone Klng Foundatlon, The Wllllam Howarth Charltable Tnjst, Yvonne Flux Charitable Twst, The Hllda Clarke Memorial Fund, The lan Askew Charitsble Trust, The Wllmcote Charltrust. Santa Barbara Hights Charitable Tru5L R G Hills Tnjst, Novia Foundatlon, the Mlchael & Anna Wix Charltable Trust Flnanclal Posltlon Durlng the year the charity raised £120.009. ExpendItU was £43,029. Our prudent management of fund5 donated by our 5UPPOrter5 kept our fundraising expendTture tojust under EO.03 for every £1 ralsed. Our surplus was £76,98D. with £72.501 in restricted funds, £22,894 in designated funds Ithe amount committed but not covered by restritted fundsl, and £84.752 in our unrestricted fund. Cash held on 31 March 2025 wa5 £181.437. Full details of both Inwme and Expenditure can be found In the notes accompanying the Ac¢ounts. The trustees are satlsfled the charity is a going conrn and fit for pyrp05e. In the Trustees vlew. the reseNes should provide the charity with adequate financial stability and the means for it to meet its charitable objectives for the foreseeable future. With no paid staff or premises. the trustees alm to hold sufficient funds to meet its primary expenditu commitments which is its research funding. Reserves The Trustees reviewthe amount of reserves gularlY. As at 31 March 2024, all the funds required for the remalnder of the existing research commitment are held in restricted1£72,5011 and designated1£22,8941 funds, and unrestricted reserves are £84,752.
SPENCER DAY14L4N MENINGITIS RESEARCH Trustees, annual report for the perlod wrtllni31 Mar¢h 2025 Pa¥ ind Expenses 5penor Dayman Menln851ls Re5earch1s a voluntary or8anlsation wlth nD pald staff. Althowh the trvstees can ¢iBlm travel expenses, none were clalmed durlng the ye•T. SimSlarly, the Scientlf Medlcal Advi50ry Panel were Dot remunerated noi dld they claim expenses. Pllns for 2025-2026 Spencer Dayrnan Menln8lti5 Research wlll contlnue to bulld on the su¢¢ess of Its first 2 years to provlde flnanclal supporttowards Innovatfve prtventatlve research Into menln8ttls, sepsls and other assoclated diseases. After dlscusslons wlth our5tlentlflc Medical Advisory Panel, we have invited stlentlsts with track tecords Into thÈ preventlon of Infertlous dlsea5es at the Spencer Dayman MenIntI5 LaboratorSes, Brlsttsl Va¢dne Centre. UnlveTslty trf Br15tol to apply for research grant ald In ihÈ flrst quarter of the financlal year 2025-26 wlth the aim of commenclngthe fundlnB of new prevèntatlve resÈaT¢h prolècis durln8 the latter part of 2025 and beyond. We wlll also ¢ontlnue to ralse awareness aboutthe5e dlsea5E5 and provide peer-to-peer support and practlcal advlce to famllies affected. There are no plans to employ pald staff ard wo will contlnue to rety on our volunteers and supporters to help us delerOu1 oblectfve5. Structure, Governaft¢e and Man•8ement Spencer DByTr8n Menlngltls Research was reg15tered wlth the Chadty Commlsslon on 6th March 2023 and wkh the Scottlsh Regulator IOSCRI on 7th August 2023. The charity Is controlled by Its 8ovwnln6 document.. Constlttrtlon of a CharStable Incorporated Organlsatlon Icio). The strateBle dlrectlon ol the rharity15 deteTmlned by the Board of Trustees In con5ult8tlon wlth the Prfnclpal Officer, Dr Stevè Dayman. TheTTU5tees meetat least 4 tlmes a yearto ensure effectlve 8ovemance and delivery against plans and budgets. A system of dèlegatlon 15 In place and dayto day rè5ponslbllity foT the operation of the chaTlty rests with the Principal offlr. Workln8 c105ely wlth the knrd, the Prlncipal Officer Is responiibbÈ for ensurlngthat the work of the charfty Is carrfed out In Ilne with the 5tlaEe8lc d1¢00 detemlned by the Board of Trustee5. The charity trustees are mindful of sviubly strllled person5 t?loln the BoBrd and, throu8h th•ir networks, they are watchful for potIal Candldates. Spencer Dayman Menlngltls Research Is a voluntary charlty with no paid staff.
SPEW(ER IIAYMAN MENIN6tnS RESEARCH TrusEees' anywal r¥port lOrt perlod wxllr4 31 Mah 2025 Rlsk Ivlanagement The Trustees are aware of the r2oulrement under the Statement of Aetommended Practite 2019 to regularly assess oper8tsn8 Strengths. weaknesses and rislts. The trustee5 haveglven consldeTrtitsn.to the major risksthe tharity rnay be exposed to and are 5atlsfied that appropriate controls are have beÈn e5t•bllshed to maaage those risk5. Fundraislng Stsndards spencer Daymttn MenIn85 Research 1$ regtstered with the Fundraising Regulator ID number. FR.ID- 274668. To date the charity has f1Ved no complaints about tts fundraising artivities since tiiwa5 reglstered in March 2023. Si8Ded on behslfofthe¢lmrtVs board oftru51eeson.. . loulse Grdham, Chalr 10
SPENCER DAYMAN MEhJlNGms RESEARCH ststemert otTrwtee RespolbIllllel 7he trustees of Sponcer Dayman Menlngltls Researth are responslble for prnparlnBtheTru$tses' Afinual Report and the flnancial statements In accordance wlth appllcable law and Unlted Klnsdom Accountln8 Startdards Iunlted Kln8dorn Genprally Accepted Accountln8 PTactl¢el. Charlty Cornmi55lon requires the trusttes to prÈparE ftnancial statprnents for eath finaftclal year whlch glve a true and falr vlew of the state of affalT5 of the charlty and of the Incomln8 résources and appllcatlon of Te50urtes. Includlng the Income and expendlture. forthat pèrfod, lft prèparlng these IlnaThclal 5tatsment5, the trustees are requlred to.. 5elertsuitable accountlng pollcles and then apply them conslst•ntly.' observe the methods and prfnc5ples In the Chirltles SORP; make judgements and estlmates that are reasonable and prudent,. state whether appllcable UK Accountlnastandards have be•n followed, sublact to any materlal departures dlsclosed and explalned In the flnanclal ststemenis., prepare the flnanclal statements on the golng concem basls unless It Is Inapproprlate to presume that the charfty wlll contlnue In operatlon. The trk15tees are respon51ble for keeplD8 adequate accountlnB recor(Isth3t ¢Jlsc105e. wsth reasonable accuracy, Bt any tlmethe financlèl posltlon of the charitable company and enabLp them to en5UTe that the flnanclal statements COmpwIth the Charltles Att 2011, the ChaTIty (Accounts and Reportsl Regulatsn5 2008 and the provlslons of thè trust deed. ThÈy are also responslble for safeguardlng the assets of thE charltable cornpany ar6d hence fortakin8 reasonable steps forthe prevention and detertlon offraud and other IfregulaTltles. Thls reportwa5 approved by the Board on ... nd sl8ned on Its behalf bv L¢)ulst Grnham, thalr
SPENCER DAYMAN mliw3[TIs RESEARCH Sndepend•ntExamlngrfs R•portto tha ynxtof sncer Da¥Tnan Ménlttgttls R¢se?reh I reportto the ch&rlry tru5tee5 on my eiamlnatlon ofthe accounts otthe Trust for the year.ended 31 March 2025. Responslbllldes and baslsof report As the trustees of the Trust you èré respon$lble for the preparatlon of the accounts In aco)rdance wlth the requirements of the Charltles and Trustee1nvestment Isojtlandl Acl 2>5 Ithe'2005 Act'l, the Charlt1fy5 A¢count5 (Scotlandl Regula05 2006185 amended) and the Cttarltles Act 20111.thè 2011 Arfl- You are sJtlJfled thet your charlty 15 not requlred by chorlty law to be audlted and have hostt Instead to have an Independ?nt exarnlTratlDn. I report In respect of my examinatlon of the Trusys accounts a$ carrled out under settion 44 Illlcl of thè 2005 Att and section 145 ofthe 2011 Act. In carrying out my exarnination I have followed the requlrements of Regulation 11 of the Charities Accounts1Scotlondl Regulatlons 200613s amended) and the pppllCab Dlre¢tlons 8lven bythe Charlty Comrn1551on under5ectlon 14515llbl ofthe 2011 ACL lttd•p¢ndent•xamln¢es stJtem•nt Slnce the frust has prÈparÈd its accounts on an atcruals basls and Is also reglstèred In Stttl3nd your 2xarniner must be a member of a body listed in ReBL6latlon 11121 of the Charltie5 Accounts Iscotlandl RegulatSon$ 2006 las amended). I can conflrrn that l am gu?Ilfied to undertake the eXamInaOn because l om a reglstered memberof ICAEW whlch is one of the Ilsted bodles. I havo comploted myexamlnatlon, I wnflrm that #o matters have cometo my atttsntlon glvlng me cause to tselle that In any matertal respect.. accountSn8 record5 were not kept In respect of the Trust a5 requlred by sectlon 44111 (al of the 2005 Act and Regulatlon 4 of the Charltle5Account5 (Scotlandl Re8uI?tlon5 20J6 la5 8rnendedl Ind sectlon 130 of the 2011 Att,. tsr 2. the accounts do not accord wlth those rerords; or 3. the accounts do not comply wtth the accountln8 requlTÈmeTrts Reguladon 8 ofthe Charltl*s Accounts (kOand} Regulatlon5 2(K16 la5 amended) and do not wmply wlth the appllcable reiulrements concernlng the fom and tDnténtDf accourrts set out in the Charitles IA¢counu and Reports) Re%ulatlon$ 2008 otherthan any ¥equlrement1hat the arcounts Ive a true and falr vlew whlch Is nota matter tonsldered as part of an IndepÈMdent èxarnlnatltsn. I have no concems and havè come across no other matters In connectlon wlth the examlnarlon to which attentlon Should be drawn in thls report in order to ènable a proper undÈrstatsdln4of the a¢count5 to be reached. Matthew Do Ins FCA Ounklews Charternd Accourtents Woodland5 Grange Woodl•nds Lano radleystoke Br15tol 6S32 4JY %4..fvJ.?..lLs l2
SPENCER DAYMAN MENINGrris RESEARCH STATEMENTQF FINANaAL AcfiviTIES {INCWDIThIG INCOME AND EXPENDITURE Accoupm FOR THE PERIOD ENDING 31 IARcH 2025 Unre5trirted Restrlrt¢d Fund5 Funds 2025 2025 Total Funds 2025 Totel Fun(ts 2024 Note5 Donations. Interest Fundra1ng events Total Income 56.346 62,765 119.111 119,046 13.219 132,265 57,244 62.765 120.LNJ9 EXpendIre on: Generating funds arltable acbvities Research Support AwarenesslEduc*ion 3.718 3,718 8,934 654 30,233 30887 4.961 3,463 9,949 4,319 5,896 4,961 3A63 Total eMpen¢frture 12,796 30,233 43,029 29,098 Net Incomebefore transfws 44A48 32,532 76,980 103,167 Transfers betyjeen fund5 Net move1 offunds In 44A48 32.S32 76,980 103,167 Reconciliation of funds: Total funds brou8hi forward Total funds Trfed fotword 63,198 107,646 39A69 72,501 103,167 180,147 io 103,167 The Ststement of Hnanual Artfvltle5 indudes all Bains and losses Tecggntsed rn the year. Ail income and expenditure derlve from continuing adLwitie 13
SPENCER DAYMAN MENINGtTIS RESEARCH BALANCE SHEEr ASAT 31 MARQI 2025 Notes Unreslrktod Funds Restrlctsd Funds 2015 2024 Curr•ntAss•ts Cash at bank 108.936 7201 18IA37 104,067 108,936 72501 181A37 104,067 Credttors Amounts du• wlthln one wr 112901 11,2901 19001 NcurrentA5S0ts 107,646 72.501 180,147 103,167 Totsl hlet Assets 107,646 7L5QI 180 147 103,16? The Funds of th* thadty Unrestrlcted Income funds Dé518nBted fund5 Restrltted Income fvnds 84,752 22,894 84,752 22,894 43,138 20,060 io 72,501 7201 39,969 107,646 72,501 180,147 103,167 Theso ac¢ouThts have been prepared In accordance wr(h the pmlslons appllcable to charltable Incorporated or8anlsatlon5. These account5 were 4pproved by the 8oaTd of Tn151ee$on..... half of the boaAI by.. are s18fi¢d on Loulse Grahim Chalr 14
SPENCER DAYMAN MENINGms RESEARCH STATEME OF CASH FLOWS FOR THE PERIOD ENDING 31 MARCH 2025 ZO25 2024 Cash ftows from operating actlvltles: Net movement in funds for the reporting period las per the statement of fi'nancial artNitiesl 76,980 103,167 Adjustments for: Decrease in debtors Increa5elldecreasel in creditors 390 900 Net cash provlded by lused Inl opÈrailng activltles 77.370 104.067 Change In cash and cash equivalents in thè rÈportin8 rIOd 77,370 104,067 Cash and cash equlvalents at the beglnnlng of the reportlng pèrlod 104,067 Cash and cash equtvalents at the end of the reportlng perlod 181,437 104,067 15
SPENCER DAYMAN MENINGMS RESEARCH NOTESTO THE ACCOU14TS FOR THE PERIOD ENDING 31 MARCH 2025 l. Accountln8 Policies The followin8 accounting pollcles have been used nSIstentlY In dea15ng with items which are considered material in relation to the charf(Vs accounts. lal Basls of Accounting The financlal 5taternents have been prepared in accordance with Accountlng and Reportlng by Charities: Statement of Recommended PractlcÈ applitable to charities preparing theii accounts in accordance wlth the Financial Reportlng Stsndard appllcable in the UK and Republlc of Ireland IFRS 1021 leffective l January 20191- ICharttie5 9)RP IFRS 10211. the Finanaal Reportlng Standard appll¢able in the UK and Republic of Ireland IFRS 1021 and the Charltles Act 2011. The charlty Is a publlc benefit entSty. The financial statements have been ppared on a golng- concern basls. The tTUStees con51der that the charity holds suffident reserves to achieve an orderly closure in the Unlike event of a loss of fundnq. The flnanclal ststement5 are presented In sterfln8 whkh Is the fvn¢tlonal currency of the charity and rounded to the nearest E. Ibl Golni Con¢ern There continues to be a need for the chadty. Wlth no paid staff, the only major expendlture ¢omrnitment is research grant fundin& and there are sufflclent fvnds at the year end. held In deslgnaled fur, to fully fund the currènt research commitments. In additlon, the charlty holds £84,752 In n$trIcted reserve& The trustee5 are sat15fled that the charlty Is a zolng concern. (¢1 Fund Accountlng Unrestrlcted funds are general funds that are avallable for use at the trustee< discretion In fuitherance of the oblectfve5 of the charlty. Restricted funds are those donated for use In a particular area or for speufic wrp05es, the use of which Is rèstrlcted to that area or purpose. ldl Income Income from donatlons, 8rants and cot)tracts Is recoBnised where there is entitlement, probablllty of receipt and the amount can be measured wlth sufflc1ent reliabiltty. Investment Income, tradln8 In¢ome and other Income are ¢0£nIsed on a recelvable ba51s. lel Expenditure Expenditure is recognlsed on an accruals basis. ExperKliture indudes any Value Added Tax whld) Is reported as part of the expenditure to which tt lates. Expendlture on geneTatlng funds comprises ¢osts a551xiated wSth attrartlng income. Expenditure on charitable actNities comprises t)se costs incUrd by the charlty In the delivery of its research. peer support and awareness raising. It includes both costs that can be allocated directty to each of these and th05e costs of an bndireci nature necessary to support them. Support costs areallocated between the expenditure categories of thestatement of Financlal Activities on a ba515 designed to refiett the use of the resource. 16
SPENCER DAYMAN MENINGITIS RESEARCH NOTES TO THE ACCOUNTS FOR THE PERIOD ENDING 31 MARCH 2025 lfj Taxation The charity is exempt from tax on income and gains falling within section 505 of the Taxes Act 1988 or sertion 252 of the Taxatlon of Char8eable Gains Act 1992 to the extent that these are applied to its charitable objects. Igl Cash at bank Cash at bank is in a current account and short term deposlt accounts. Ihl Creditors Creditors are recognlsed where the charity has an obligation that will result in the transfer of funds to B thlrd party and the amount due to settle the obli8ation can be measured or estlmated reliably. lil DÈbtors Debtor5 are recognised where there is an obligation that wll result in the transfer of funds to the charity and the amount owing can be measured. 2 Income from Donations Unrestricted Restricted 2025 2024 Donations Gift Aid Trusts & Grants Legacies Gift5 in Kind 33,535 2,197 9,250 10,146 1.218 33,535 2,197 72,015 10,146 1,218 39,880 626 47.126 23,714 7,700 62,765 56,346 62,765 119,111 119,046 3 Expendlture on charltable activltles Unre5trlcted Re5trlcted 2025 2024 Volunteer Expenses incl Travel Research Grants & Equlpment Comms (incl PR & printed materials) WeblDlgltal Postage & Stationery Support Costs (Note 4a) Governance (Note 4a) 3,988 3,988 30,233 1,480 730 862 368 1.650 3.672 7,907 2,074 4,268 389 553 1,300 30,233 1,480 730 862 368 1,650 9,078 30,233 39,310 20,164 17
SPENCER DAYMAN MENINGITIS RESEARCH NOTE5 TO THE ACCOUNTS FOR THE PERIOD ENDING 31 MARCH 2025 4a Analysis of Support & Governance Costs 2025 Support Research Support Awareness Total Fundraisi Charltable Actlvltles rotsl 2025 IT costs Insurance Ico 29 65 13 107 117 66 13 196 146 196 26 368 61 66 14 141 207 262 40 509 65 6S Govemano Research Support Awareness Totsl Fundraislng ChaTltsble Activities Total 2025 Independenr Examiner Professional Advl Tax Return 340 340 1.020 1,020 120 120 120 360 360 90 90 90 270 270 550 550 550 1.650 1,650 4b Analysls ol Support & Governance Costs 2024 Support Research Support Awarene55 Total Fundraisin8 Charitable Actlvltles Total 2024 IT Set up costs Insurance 127 58 126 58 127 57 127 57 507 230 173 185 184 553 184 737 Governancè Research Support Awareness Total Fundraisin8 Charltable Activitles Total 2024 Professional Fees re Set up 134 133 133 4c) Independent Examiner 300 300 300 9CX) 90) 434 433 433 1,300 1.300 18
SPENCER DAYMAN MENINGITIS RESEARCH NOTES TO THE ACCOUNTS FOR THE PERIOD ENDING 31 MARCH 2025 5 Independent Examinerfs Remuneration 2025 2024 IE Fees 1.020 900 6 Staff Costs There are no staff employed by the charlty. No trustees have been pald any remuneratlon or recelved any beneflts from an employment wlthln the charlty.12024- £01 7 Relatsd Party Transartlons Donations were made by 2 trnstèes,, 2025 2024 Quentin Stott Stephen Gazard 10,116 677 10,793 Expenses were pald to our Prlnclpal offlr, Dr Steve Dayman MBE.. 2025 2024 Travel & Subslstence IT Costs Fundralslng Support Costs PostaBe & StatSonery Comm5 4,355 151 241 6,472 547 377 1,406 63 519 6,256 7,915 No trustees had expenses relmbursed.12024- £01 8 Credltors~ Amounts Falllng Due Wlthln One Year 2025 2024 Accrua15 and other creditors 1,290 900 1,290 900 19
SPENCER DAYMAN MENINGIT15 RESEARCH NOTES TO THE ACCOUNTS FOR THE PERIOD ENDING 31 MARCH 2025 9a Analysi5 of Net A55ets bÈtween Funds Currentyear 2025 Unrestricted 2025 Cash Creditors less than l year 108,936 11.2901 107.646 72.501 181.437 11,2901 180,147 72.501 9b Analysis of NetAssets between Fund5 Prevtous year 2024 Unrestricted Restrirted Z024 Cash Creditors le5S than l year 64.098 19cKII 63.198 39,969 104.IA7 19001 103,167 39,969 10 Movements on Funds Balan 31 Mar 2024 Current Year Balance 31 Mar2025 Income Expenditure Transfers Restrtcted Funds Rèsearch Total Restrided Funds 39,969 39969 62,765 62,765 130.2331 130.233 72,501 72.501 Designated Funds 20 2,834 22A94 Unrestricted FrS 43.138 57,244 111796) 12,8341 84.752 rotsl Funds 103.167 120AK19 {43.0291 180,147 Research Fund: Fund5 reIVed towards current saenttfic re5e?rth project belng undertaken at Spencer Dayman Laboratories at Bristol Universlty. Designated Fund-. Funds required for the completlon of the current research projett commitment. 20