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2021-07-31-accounts

Charity Registration No. 1179130

Company Registration No. 07855645 (England and Wales)

GENESIS RESEARCH TRUST

ANNUAL REPORT AND FINANCIAL STATEMENTS

FOR THE YEAR ENDED 31 JULY 2021

GENESIS RESEARCH TRUST

LEGAL AND ADMINISTRATIVE INFORMATION

Trustees Professor Lord R M L Winston
Professor P R Bennet
Professor S Franks
Ms A Hodes
Mrs L C Lofus
Mr A S Rosenfelder
Secretary Mrs L C Lofus
Charity number 1179130
Company number 07855645
Director of Services Stephen Buton
Registered ofce Wolfson & Weston Research Centre Family Health
IRDB Building
Imperial College London
Hammersmith Hospital
Du Cane Road
London
W12 0NN
Auditor HW Fisher LLP
Acre House
11-15 William Road
London
NW1 3ER
United Kingdom
Bankers HSBC Bank Plc
281 Chiswick Hgh Road
Chiswick
London
W4 4HJ
Investment advisors Veritas Investment Management (UK) Limited
90 Long Acre
London
WC2E 9RA

GENESIS RESEARCH TRUST

CONTENTS

Page
Trustees' report 1-7
Statement of Trustees' responsibilites 8
Independent auditor's report 9 - 11
Statement of fnancial actvites 12 - 13
Summary income and expenditure account 14
Balance sheet 15
Statement of cash fows 16
Notes to the fnancial statements 17 - 31

GENESIS RESEARCH TRUST

TRUSTEES’ REPORT (INCLUDING DIRECTORS’ REPORT)

FOR THE YEAR ENDED 31 JULY 2021

INTRODUCTION

The Trustees are pleased to present their Trustees’ report together with the financial statements of the charity for the year ended 31 July 2021, which are also prepared to meet the requirements for a directors’ report and financial statements for Companies Act purposes.

The financial statements comply with the Companies Act 2006, the Memorandum and Articles of Association, and Accounting and Reporting by Charities: Statements of Recommended Practice applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS 102) (effective 1 January 2019).

OUR PURPOSE AND ACTIVITIES

The objectives of the Trust are:

In order to achieve these objectives, the Trust acts as a grant making body, raising funds to provide financial assistance for medical research and for teaching in the field of gynaecology, obstetrics and related fields in paediatrics. Most activities supported by the Trust are centred at the Institute of Reproductive and Developmental Biology at the Wolfson and Weston Research Centre for Family Health and at Queen Charlotte’s and Hammersmith Hospitals. Additionally, the Trust funds some academic activity within the ‘Division of Cancer, Institute of Reproductive Developmental Biology’, Imperial College London.

The Trust is situated in the Institute of Reproductive Developmental Biology (IRDB) Building on the Imperial College Campus at Hammersmith Hospital. This building was opened in February 2002. The bulk of the funds for the building – over £13 million - were raised by The Trust and donated to Imperial College who owns the building now. A Covenant is in place between The Trust and Imperial College that restricts use of the building to activities that are aligned to The Trust’s Objectives.

Grant Giving Guidelines

The Trust operates four funds to support research and educational activities related to women’s health:

Applications for grants from the General Research Fund are invited twice a year, up to £50,000 of unrestricted income is available for allocation by the Scientific Advisory Committee at each meeting, totalling c£100,000 of grants from this income per year. Further amounts are awarded by the Board of Trustees each year to relevant research and equipment, with decisions made at the Board meetings.

1

GENESIS RESEARCH TRUST

TRUSTEES’ REPORT (INCLUDING DIRECTORS’ REPORT) (CONTINUED)

FOR THE YEAR ENDED 31 JULY 2021

Scope of grant making

To support research into the causes, prevention, diagnosis and treatment of clinical problems associated with fertility and conception, foetal and maternal diseases and disorders in order reduce the rates of preterm birth, stillbirth, infertility and diseases of genetic or inherited origin.

Eligibility

Funding is focused for research undertaken within the IRDB at the Hammersmith and Queen Charlotte’s Hospital site though not limited to it. Clinical and scientific staff working on these sites are eligible. The Board of Trustees may occasionally decide to award grants to work undertaken elsewhere including outside Imperial College London, where this fits with a core objective of the Trust.

Assessment

All applications are assessed by the Scientific Advisory Committee. The Scientific Advisory Committee makes recommendations to the Trustees twice a year at Board meetings as to which grants should be awarded. The final decision on successful applications sits with the Board.

MEASURES OF SUCCESS

Our projects are reviewed by our Scientific Advisory Committee and through compulsory external peer review. In addition, each research project is subject to the rigorous academic review processes of Imperial College. Each year the project heads report to the Trust on progress at key intervals and are expected to deliver an annual report of output including publications. Success is judged in terms of impact on our core objectives, new procedures, products and inventions and student progression.

Public Benefit

In shaping our objectives for the year and planning activities, the Trustees have considered the Charity Commission’s guidance on Public Benefit, including the guidance “Public Benefit: running a charity (PD2).

Our mission is to reduce harm and suffering to babies and families caused by treatable conditions and complications.

We seek to fund research that will deliver the following outcomes in the public benefit:

ACHIEVEMENTS AND PERFORMANCE

Overall, the Trust raised £1,178,630 in the last financial year.

2

GENESIS RESEARCH TRUST

TRUSTEES’ REPORT (INCLUDING DIRECTORS’ REPORT) (CONTINUED)

FOR THE YEAR ENDED 31 JULY 2021

Fundraising Strategy

The Trust fundraises to generate funds for research and grants. Income is generated in the following ways:

Courses and Symposia

Genesis Research Trust contributes significantly towards postgraduate teaching and medical education through its training programme, run by The Symposium Office. This is a core means of delivering GRT’s purpose as well as to share knowledge and encourage best practice in clinical care.

The target audiences include medical specialists such as GPs, practice nurses, paediatricians, neonatologists, obstetricians, gynaecologists, gynaecological nurses, foetal medicine specialists, radiologists, radiographers, midwives, complementary therapists, physicians and obstetric anaesthetists.

STRUCTURE, GOVERNANCE AND MANAGEMENT

Governing document

The operating name of the charity is ‘Genesis Research Trust’ (GRT). The charity was first registered as a charity on 7 August 1985, and from that date until 31 July 2018 it was an unincorporated Charitable Trust.

Genesis Research Trust (the word ‘Limited’ being omitted by licence from the Department of Trade) is registered under the Companies Act 2006 as a company limited by guarantee and not having a capital divided by shares.

The company was incorporated on 21 November 2011 and is a registered charity constituted as a Limited Company under the Memorandum and Articles of Association. The charity registration number is 1179130 and the company registration number is 07855645.

The core objective of the Trust is the promotion of healthy pregnancy and childbirth. There are no restrictions in the way the charity can operate in order to meet its objectives. Current funding is directed towards activities undertaken at the Institute of Reproductive Developmental Biology at Imperial College, London and selected other institutions.

3

GENESIS RESEARCH TRUST

TRUSTEES’ REPORT (INCLUDING DIRECTORS’ REPORT) (CONTINUED) FOR THE YEAR ENDED 31 JULY 2021

Recruitment and appointment of Trustees

As set out in the Articles of Association, the chair of the Board of Trustees is nominated by the Trustees. The Trustees of the organisation are also the directors for the purposes of company law.

The Board of Trustees have power to appoint additional Trustees as it considers fit to do so and there is no limit to the number of years for which a Trustee may serve.

The Trustees who served during the year and up to the date of approval of the financial statements were:

Professor Lord R M L Winston Professor P R Bennett Professor S Franks Ms A Hodes Mrs L C Loftus Mr A S Rosenfelder

The Trustees have no beneficial interest in the company other than as members and each guarantee to contribute £1 in event of a winding up. Related party transactions are disclosed in note 27.

Trustees have power of discretion over the use of funds held by the Trust but are advised by the Scientific Advisory Committee and the Executive team. Trustees meet annually to set and agree operating strategy, and quarterly to review activities and impact with the executive team.

Trustee induction and training

The Trustees maintain a good working knowledge of charity and company law and best practice. New Trustees are provided with a copy of the company’s Memorandum and Articles of Association and there are informal procedures in place for their training and induction.

Organisation

The Board of Trustees meets regularly during the year to oversee the management of the affairs of the Trust. The Board comprises members from a variety of backgrounds and there are sub-committees dealing with various aspects of the operation. The Director of Services oversees the day to day operations of the organisation. All major decisions are ratified by the Board of Trustees.

The Trust is not significantly dependent on the services of unpaid volunteers.

Risk review

The Trustees have established a Finance and Risk Committee to analyse and identify risks facing the Trust and report these risks to the Trustees. The aim is to minimise and reduce risk and the process remains under continuous review.

The Trustees consider the key risks and uncertainties facing the charity and their plans and strategies for managing these risks to be:

4

GENESIS RESEARCH TRUST

TRUSTEES’ REPORT (INCLUDING DIRECTORS’ REPORT) (CONTINUED) FOR THE YEAR ENDED 31 JULY 2021

Related parties

The Charity works closely with the Institute of Reproductive and Developmental Biology at the Wolfson and Weston Research Centre for Family Health and at Queen Charlotte’s and Hammersmith Hospitals. None of the charity’s trustees are Directors or Trustees of these other organisations.

Pay policy for senior staff

The finance and remuneration sub-committee reviews annually the salary and employment conditions of the Director of Services, taking into account performance, market rates and the charity’s financial position.

The Director of Services reviews annually the pay of the team in consultation with the Chair of the Trustees.

FINANCIAL REVIEW

In the year under review, the Trust raised £1,178,630 and expenditure was £902,828.

Principal Funding Sources

The main principal funding sources are Donations received in the year, amenity funds and symposium income.

Details of principal funding sources are shown in notes 3 to 6.

Investment powers and policy

Under the Memorandum and Articles of Association, the charity has the power to make any investment which the Trustees see fit. The Trustees have considered the most appropriate policy for investing funds and have found that cash deposits meet their requirements to generate income.

The main fund

In the year to 31st July 2021, the investment portfolio returned +16.7% (total return after all costs) which compared favourably with the return of the benchmark (UK CPI +3%) of +5.0%. Markets recovered following the significant central bank support for economies in response to the outbreak of covid and an industry benchmark provided by Asset Risk Consultants for a medium risk strategy similar to this one adopted by the charity returned +16.8%.

APST fund

In January 2021, the trustees appointed Veritas Investment Partners (UK) Ltd, to manage these funds. The performance from 1st of February to 31st July 2021 was +4.9% (total return after all costs) which compared favourably with the return of the benchmark (UK CPI +3%) of +3.6%. The industry benchmark provided by Asset Risk Consultants for a medium risk strategy similar to the one adopted by the charity returned +7.3%. This underperformance was due to the managers taking a cautious approach to investing cash given valuations of both bonds and equities.

Markets have become increasingly volatile during the current year to 31st July 2022 and the portfolios have declined in the year to date. The managers retain significant cash balances in both portfolios notwithstanding the increase in inflation. There have been discussions with the Veritas Investment Partners (UK) Ltd to ensure that sufficient cash and short dated bonds are held to meet any committed funding requirements.

5

GENESIS RESEARCH TRUST

TRUSTEES’ REPORT (INCLUDING DIRECTORS’ REPORT) (CONTINUED) FOR THE YEAR ENDED 31 JULY 2021

Reserves Policy

The Trust maintains reserves at a level which minimises the impact of short-term income volatility or economic downturn and enables the Trust to manage financial risk. Income is generated through a range of fundraising activities including sponsored challenge and medical conferences. This income is used to fund research that supports the Trust’s core objects. The Trustees are committed to funding vital research that will deliver evidence-based results for reproductive medical treatments and outcomes of worldwide significance. The level of reserves ensures that key research can continue in the event of a temporary shortfall in income.

The Trust’s total reserves at 31 July 2021 were £6,093,059. The unrestricted funds not designated or invested in tangible fixed assets held by the charity are £3,173,945.

Details of reserves are shown in notes 23-25.

FUTURE PLANS AND DEVELOPMENT

The Trustees reported their intentions last year and Genesis Research Trust has completed the simplification of the non-scientific activities so that the Trust is now in response mode.

In making this change, Trustees are very grateful to all the Team for their continued support and commitment throughout the process. As of the year end, its two principal pillars are Grant making and the series of academic symposia arranged by our Symposium Office team.

The Trustees have also continued to map out the strategy of the Trust to secure the future of our activities at Imperial College. They remain committed to the original objective of undertaking research into women’s health with emphasis on the areas related to pregnancy, reproduction, fertility, epigenetics and some aspects of cancer affecting women. They also recognise that a combination of both academic and translational clinical research will continue to be of importance. The Trust’s historical funding of the Institute of Reproduction and Developmental Biology (IRDB building gifted to Imperial College) resulted in a successful track record. With the allocation of funding from Genesis, the research has helped progress in these areas. The Trustees fully recognise however that more is needed and this will be supported by the capital available to Genesis which the Trustees plan to supplement over time.

The Trustees, while assisting with some limited project funding, will continue to allocate funds over the coming years to support merit-based Ph.D studentships, each with an expected duration of up to 4 years. The trustees have long recognised they also need to support the creation of academic positions within the IRDB. For some years the search for a suitable clinical academic to fill a chair in reproductive medicine has been unsuccessful. This is partly because movement to London and the high cost of living here has deterred appropriate candidates. We recognise that clinical academic leaders will be essential for the continued success of work in the IRDB and the trustees have considered supporting promising younger candidates to grow into maintaining the life and excellence of the intellectual and scientific capital the trust wishes to promote. The Trustees anticipate funding such posts internally and in collaboration with partners.

Going concern

The Trustees completed a review of the Trust’s planned symposium and other programs, processes have been put in place to ensure the viability of the Trust and its commitment to meeting its primary objective of research funding.

6

GENESIS RESEARCH TRUST

TRUSTEES’ REPORT (INCLUDING DIRECTORS’ REPORT) (CONTINUED)

FOR THE YEAR ENDED 31 JULY 2021

The Trust, through its existing reserves is well positioned to meet all of its commitments in grants and scholarships.

Statement of Fundraising Practice

The Trustees wish to acknowledge and thank our dedicated fundraisers who have undertaken a challenge event over the past year in support of Genesis Research Trust. We also appreciate the Trusts and companies who have supported the charity.

Disclosure of information to auditor

Each of the Trustees has confirmed that there is no information of which they are aware which is relevant to the audit, but of which the auditor is unaware. They have further confirmed that they have taken appropriate steps to identify such relevant information and to establish that the auditor is aware of such information.

Auditor

HW Fisher LLP was appointed auditor to the charity and a resolution proposing that the firm be re-appointed will be put to the next Annual General Meeting.

On behalf of the Board of Trustees

Robert Winston

------------------------------------------------Professor Lord R M L Winston

Trustee

26 Jul 2022 Date:

7

GENESIS RESEARCH TRUST

STATEMENT OF TRUSTEES' RESPONSIBILITIES

FOR THE YEAR ENDED 31 JULY 2021

The Trustees, who are also the directors of Genesis Research Trust for the purpose of company law, are responsible for preparing the Trustees' Report and the financial statements in accordance with applicable law and United Kingdom Accounting Standards (United Kingdom Generally Accepted Accounting Practice).

Company Law requires the Trustees to prepare financial statements for each financial year which give a true and fair view of the state of affairs of the Trust and of the incoming resources and application of resources, including the income and expenditure, of the charitable company for that year.

In preparing these financial statements, the Trustees are required to:

The Trustees are responsible for keeping adequate accounting records that disclose with reasonable accuracy at any time the financial position of the Trust and enable them to ensure that the financial statements comply with the Companies Act 2006. They are also responsible for safeguarding the assets of the Trust and hence for taking reasonable steps for the prevention and detection of fraud and other irregularities.

GENESIS RESEARCH TRUST

INDEPENDENT AUDITOR'S REPORT

TO THE MEMBERS OF GENESIS RESEARCH TRUST

Opinion

We have audited the financial statements of Genesis Research Trust (the ‘Trust’) for the year ended 31 July 2021 which comprise the statement of financial activities, the summary income and expenditure account, the balance sheet, the statement of cash flows and the notes to the financial statements, including significant accounting policies. The financial reporting framework that has been applied in their preparation is applicable law and United Kingdom Accounting Standards, including FRS 102 The Financial Reporting Standard applicable in the UK and Republic of Ireland (United Kingdom Generally Accepted Accounting Practice).

In our opinion, the financial statements:

Basis for opinion

We conducted our audit in accordance with International Standards on Auditing (UK) (ISAs (UK)) and applicable law. Our responsibilities under those standards are further described in the Auditor's responsibilities for the audit of the financial statements section of our report. We are independent of the Trust in accordance with the ethical requirements that are relevant to our audit of the financial statements in the UK, including the FRC’s Ethical Standard, and we have fulfilled our other ethical responsibilities in accordance with these requirements. We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our opinion.

Conclusions relating to going concern

In auditing the financial statements, we have concluded that the Trustees' use of the going concern basis of accounting in the preparation of the financial statements is appropriate.

Based on the work we have performed, we have not identified any material uncertainties relating to events or conditions that, individually or collectively, may cast significant doubt on the Trust’s ability to continue as a going concern for a period of at least twelve months from when the financial statements are authorised for issue.

Our responsibilities and the responsibilities of the Trustees with respect to going concern are described in the relevant sections of this report.

Other information

The other information comprises the information included in the annual report other than the financial statements and our auditor's report thereon. The Trustees are responsible for the other information contained within the annual report. Our opinion on the financial statements does not cover the other information and, except to the extent otherwise explicitly stated in our report, we do not express any form of assurance conclusion thereon. Our responsibility is to read the other information and, in doing so, consider whether the other information is materially inconsistent with the financial statements or our knowledge obtained in the course of the audit, or otherwise appears to be materially misstated. If we identify such material inconsistencies or apparent material misstatements, we are required to determine whether this gives rise to a material misstatement in the financial statements themselves. If, based on the work we have performed, we conclude that there is a material misstatement of this other information, we are required to report that fact.

We have nothing to report in this regard.

Opinions on other matters prescribed by the Companies Act 2006

In our opinion, based on the work undertaken in the course of our audit:

Matters on which we are required to report by exception

In the light of the knowledge and understanding of the Trust and its environment obtained in the course of the audit, we have not identified material misstatements in the directors' report included within the Trustees' report.

GENESIS RESEARCH TRUST

INDEPENDENT AUDITOR'S REPORT (CONTINUED)

TO THE MEMBERS OF GENESIS RESEARCH TRUST

We have nothing to report in respect of the following matters in relation to which the Companies Act 2006 requires us to report to you if, in our opinion:

Responsibilities of Trustees

As explained more fully in the statement of Trustees' responsibilities, the Trustees, who are also the directors of the Trust for the purpose of company law, are responsible for the preparation of the financial statements and for being satisfied that they give a true and fair view, and for such internal control as the Trustees determine is necessary to enable the preparation of financial statements that are free from material misstatement, whether due to fraud or error. In preparing the financial statements, the Trustees are responsible for assessing the Trust’s ability to continue as a going concern, disclosing, as applicable, matters related to going concern and using the going concern basis of accounting unless the Trustees either intend to liquidate the charitable company or to cease operations, or have no realistic alternative but to do so.

Auditor's responsibilities for the audit of the financial statements

Our objectives are to obtain reasonable assurance about whether the financial statements as a whole are free from material misstatement, whether due to fraud or error, and to issue an auditor's report that includes our opinion. Reasonable assurance is a high level of assurance but is not a guarantee that an audit conducted in accordance with ISAs (UK) will always detect a material misstatement when it exists. Misstatements can arise from fraud or error and are considered material if, individually or in the aggregate, they could reasonably be expected to influence the economic decisions of users taken on the basis of these financial statements.

Irregularities, including fraud, are instances of non-compliance with laws and regulations. We design procedures in line with our responsibilities, outlined above, to detect material misstatements in respect of irregularities, including fraud. The extent to which our procedures are capable of detecting irregularities, including fraud, is detailed below.

As part of our planning process:

Owing to the inherent limitations of an audit, there is an unavoidable risk that we may not have detected some material misstatements in the financial statements even though we have properly planned and performed our audit in accordance with auditing standards. The primary responsibility for the prevention and detection of irregularities and fraud rests with the trustees of the charity.

GENESIS RESEARCH TRUST

INDEPENDENT AUDITOR'S REPORT (CONTINUED)

TO THE MEMBERS OF GENESIS RESEARCH TRUST

A further description of our responsibilities is available on the Financial Reporting Council’s website at: https://www.frc.org.uk/ auditorsresponsibilities. This description forms part of our auditor's report.

Use of our report

This report is made solely to the charitable company's members, as a body, in accordance with Chapter 3 of Part 16 of the Companies Act 2006. Our audit work has been undertaken so that we might state to the charitable company's members those matters we are required to state to them in an auditor's report and for no other purpose. To the fullest extent permitted by law, we do not accept or assume responsibility to anyone other than the charitable company and the charitable company’s members as a body, for our audit work, for this report, or for the opinions we have formed.

Andrew Rich

Andrew Rich (Senior Statutory Auditor)

for and on behalf of HW Fisher LLP

Chartered Accountants Statutory Auditor Acre House 11-15 William Road London NW1 3ER United Kingdom 26 Jul 2022 .........................

GENESIS RESEARCH TRUST

STATEMENT OF FINANCIAL ACTIVITIES

FOR THE YEAR ENDED 31 JULY 2021

Current fnancial year
Unrestricted
Unrestricted
funds
funds
general
designated
2021
2021
Notes
£
£
Income from:
Donatons and legacies
3
776,527
33,350
Charitable actvites
4
113,978
-
Fundraising actvites
5
4,782
-
Investments
6
71,980
-
Total income and endowments
967,267
33,350
Expenditure on:
Raising funds
7
220,250
-
Charitable actvites
8
576,083
63,496
Total resources expended
796,333
63,496
Net gains/(losses) on
investments
13
540,024
-
Net movement in funds
710,958
(30,146)
Fund balances at 1 August
2020
2,463,480
630,909
Fund balances at 31 July
2021
3,174,438
600,763
Restricted
Endowment
funds
funds
2021
2021
£
£
-
171,210
-
-
-
-
6,803
-
6,803
171,210
-
42,999
-
-
-
42,999
-
46,914
6,803
175,125
90,771
2,045,159
97,574
2,220,284
Total
2021
£
981,087
113,978
4,782
78,783
1,178,630
263,249
639,579
902,828
586,938
862,740
5,230,319
6,093,059
Total
2020
£
2,141,533
431,279
42,860
76,171
2,691,843
285,913
703,389
989,302
210,898
1,913,439
3,316,880
5,230,319

The statement of financial activities includes all gains and losses recognised in the year.

All income and expenditure derive from continuing activities.

GENESIS RESEARCH TRUST

STATEMENT OF FINANCIAL ACTIVITIES (CONTINUED)

FOR THE YEAR ENDED 31 JULY 2021

Prior fnancial year
Unrestricted
Unrestricted
funds
funds
general
designated
2020
2020
Notes
£
£
Income from:
Donatons and legacies
3
61,774
34,600
Charitable actvites
4
431,279
-
Fundraising actvites
5
42,860
-
Investments
6
76,171
-
Total income and endowments
612,084
34,600
Expenditure on:
Raising funds
7
285,913
-
Charitable actvites
8
647,432
55,957
Total resources expended
933,345
55,957
Net gains/(losses) on investments
13
210,898
-
Gross transfers between funds
14
159,703
(159,703)
Net movement in funds
49,340
(181,060)
Fund balances at 1 August 2019
2,414,140
811,969
Fund balances at 31 July 2020
2,463,480
630,909
Restricted
Endowment
funds
funds
2020
2020
£
£
-
2,045,159
-
-
-
-
-
-
-
2,045,159
-
-
-
-
-
-
-
-
-
-
-
2,045,159
90,771
-
90,771
2,045,159
Total
2020
£
2,141,533
431,279
42,860
76,171
2,691,843
285,913
703,389
989,302
210,898
-
1,913,439
3,316,880
5,230,319

The statement of financial activities includes all gains and losses recognised in the year.

All income and expenditure derive from continuing activities.

GENESIS RESEARCH TRUST

SUMMARY INCOME AND EXPENDITURE ACCOUNT

FOR THE YEAR ENDED 31 JULY 2021

All income funds
2021
£
Gross income
1,007,420
Gains on investments
540,024
Total income in the reportng period
1,547,444
Total expenditure from income funds
859,829
Net income/(expenditure) for the year
687,615
2020
£
646,684
210,898
857,582
989,302
(131,720)

GENESIS RESEARCH TRUST

BALANCE SHEET

AS AT 31 JULY 2021

Notes
Fixed assets
Tangible assets
15
Investments
16
Current assets
Debtors
18
Investments
19
Cash at bank and in hand
Creditors: amounts falling due within one year
20
Net current (liabilites)/assets
Total assets less current liabilites
Capital funds
Endowment funds
23
Income funds
Restricted funds
24
Unrestricted funds
Designated funds
25
General unrestricted funds
2021
£
228,020
-
71,882
299,902
(610,523)
600,763
3,174,438
£
493
6,403,187
6,403,680
(310,621)
6,093,059
2,220,284
97,574
3,775,201
6,093,059
2020
£
40,202
1,558,297
592,442
2,190,941
(466,866)
630,909
2,463,480
£
1,964
3,504,280
3,506,244
1,724,075
5,230,319
2,045,159
90,771
3,094,389
5,230,319

The financial statements were approved by the Trustees on ...26 July 2022......................

Robert Winston

..............................

Professor Lord R M L Winston

Trustee

Company Registration No. 07855645

GENESIS RESEARCH TRUST

STATEMENT OF CASH FLOWS

FOR THE YEAR ENDED 31 JULY 2021

2021
Notes
£
£
Cash fows from operatng actvites
Cash generated from/(absorbed by) operatons
28
1,782,008
Investng actvites
Purchase of tangible fxed assets
-
Cash (invested in)/withdrawn from investment
portolio
(2,302,593)
Investment income received
25
Net cash (used in)/generated from investng
actvites
(2,302,568)
Net cash used in fnancing actvites
-
Net (decrease)/increase in cash and cash equivalents
(520,560)
Cash and cash equivalents at beginning of year
592,442
Cash and cash equivalents at end of year
71,882
2020
£
(4,413)
674,809
141
£
(169,563)
670,537
-
500,974
91,468
592,442

GENESIS RESEARCH TRUST

NOTES TO THE FINANCIAL STATEMENTS

FOR THE YEAR ENDED 31 JULY 2021

1 Accounting policies

Charity information

Genesis Research Trust is a private company limited by guarantee governed by its Memorandum and Articles of Association and incorporated in England and Wales. The registered office is Wolfson & Weston Research Centre Family Health, IRDB Building, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 0NN.

1.1 Accounting convention

The financial statements have been prepared in accordance with the Trust's governing document, the Companies Act 2006 and "Accounting and Reporting by Charities: Statement of Recommended Practice applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS 102) (effective 1 January 2019)". The Trust is a Public Benefit Entity as defined by FRS 102.

The financial statements are prepared in sterling, which is the functional currency of the Trust. Monetary amounts in these financial statements are rounded to the nearest £.

The financial statements have been prepared under the historical cost convention, modified to include the valuation certain financial instruments at fair value. The principal accounting policies adopted are set out below.

1.2 Going concern

The Trustees completed a review of the Trust’s planned symposium and other programs, processes have been put in place to ensure the viability of the Trust and its commitment to meeting its primary objective of research funding.

The Trust, through its existing reserves is well positioned to meet all of its commitments in grants and scholarships.

Whilst the pandemic has caused some disruption to date, not least by reducing our fundraising income for 2021, at the time of approving the financial statements, the Trustees have a reasonable expectation that the Trust has adequate resources to continue in operational existence for the foreseeable future. Thus the Trustees continue to adopt the going concern basis of accounting in preparing the financial statements.

1.3 Charitable funds

Unrestricted funds are available for use at the discretion of the Trustees in furtherance of their charitable objectives.

Designated funds comprise funds which have been set aside at the discretion of the Trustees for specific purposes. The purposes and uses of the designated funds are set out in the notes to the financial statements.

Restricted funds are subject to specific conditions by donors as to how they may be used. The purposes and uses of the restricted funds are set out in the notes to the financial statements.

Endowment funds are subject to specific conditions by donors that the capital must be maintained by the Trust.

1.4 Income

Income is recognised when the Trust is legally entitled to it after any performance conditions have been met, the amounts can be measured reliably, and it is probable that income will be received.

Cash donations are recognised on receipt. Other donations are recognised once the Trust has been notified of the donation, unless performance conditions require deferral of the amount. Income tax recoverable in relation to donations received under Gift Aid or deeds of covenant is recognised at the time of the donation. Services in kind are recognised at the value the Trust would be prepared to pay on the open market for what it receives.

Legacies are recognised on receipt or otherwise if the Trust has been notified of an impending distribution, the amount is known, and receipt is expected. If the amount is not known, the legacy is treated as a contingent asset.

GENESIS RESEARCH TRUST

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)

FOR THE YEAR ENDED 31 JULY 2021

(Continued)

Gifts in kind comprise the provision of office space. Gifts in kind are included in income and expenditure at a reasonable estimate of their value to the charity.

Government grants are recognised at the fair value of the amount received or receivable when thereis reasonable assurance that the grant conditions will be met and the grants will be received. The charity has received grants under the Coronavirus Job Retention Scheme. The scheme is designed to compensate for staff costs, so amounts received or receivable are recognised in the income statement as part of other operating income over the same period as the costs to which they relate. Government grants are accounted for under the performance model.

1.5 Expenditure

Expenditure is recognised on an accruals basis, inclusive of value added tax.

Expenditure relating to charitable activities are those elements of expenditure directly incurred in performing these activities.

Grants payable are payments made to third parties in the furtherance of the charitable objects of the charity. In the case of an unconditional grant offer this is accrued once the recipient has been notified of the grant award.

Support costs are allocated based on the proportion of direct costs allocated to each activity.

Governance costs comprise all costs involving the public accountability of the charity and its compliance with regulation and good practice.

1.6 Tangible fixed assets

Tangible fixed assets are initially measured at cost and subsequently measured at cost, net of depreciation and any impairment losses.

Depreciation is recognised so as to write off the cost of assets less their residual values over their useful lives on the following bases:

Computers

3 years straight line

The gain or loss arising on the disposal of an asset is determined as the difference between the sale proceeds and the carrying value of the asset, and is recognised in net income/(expenditure) for the year.

1.7 Fixed asset investments

Fixed asset investments are initially measured at transaction price excluding transaction costs, and are subsequently measured at fair value at each reporting date. Changes in fair value are recognised in net income/(expenditure) for the year. Transaction costs are expensed as incurred.

1.8 Impairment of fixed assets

At each reporting end date, the Trust reviews the carrying amounts of its tangible assets to determine whether there is any indication that those assets have suffered an impairment loss. If any such indication exists, the recoverable amount of the asset is estimated in order to determine the extent of the impairment loss (if any).

1.9 Cash and cash equivalents

Cash and cash equivalents include cash in hand, deposits held at call with banks, other short-term liquid investments with original maturities of three months or less.

GENESIS RESEARCH TRUST

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)

FOR THE YEAR ENDED 31 JULY 2021

1 Accounting policies

(Continued)

1.10 Financial instruments

The Trust has elected to apply the provisions of Section 11 ‘Basic Financial Instruments’ and Section 12 ‘Other Financial Instruments Issues’ of FRS 102 to all of its financial instruments.

Financial instruments are recognised in the Trust's balance sheet when the Trust becomes party to the contractual provisions of the instrument.

Financial assets and liabilities are offset, with the net amounts presented in the financial statements, when there is a legally enforceable right to set off the recognised amounts and there is an intention to settle on a net basis or to realise the asset and settle the liability simultaneously.

1.11 Employee benefits

The cost of any unused holiday entitlement is recognised in the period in which the employee’s services are received.

Termination benefits are recognised immediately as an expense when the Trust is demonstrably committed to terminate the employment of an employee or to provide termination benefits.

1.12 Retirement benefits

Payments to defined contribution retirement benefit schemes are charged as an expense as they fall due.

2 Critical accounting estimates and judgements

In the application of the Trust’s accounting policies, the Trustees are required to make judgements, estimates and assumptions about the carrying amount of assets and liabilities that are not readily apparent from other sources. The estimates and associated assumptions are based on historical experience and other factors that are considered to be relevant. Actual results may differ from these estimates.

The estimates and underlying assumptions are reviewed on an ongoing basis. Revisions to accounting estimates are recognised in the period in which the estimate is revised where the revision affects only that period, or in the period of the revision and future periods where the revision affects both current and future periods. There were no significant accounting estimates or judgements in the year.

Total 2020 £ 96,374 2,045,159 - 2,141,533 59,324 37,050 96,374 - - -
Endowment funds 2020 £ - 2,045,159 - 2,045,159 - - - - - -
Unrestricted funds designated 2020 £ 34,600 - - 34,600 34,600 - 34,600 - - -
Unrestricted funds general 2020 £ 61,774 - - 61,774 24,724 37,050 61,774 - - -
Total 2021 £ 114,639 639,210 227,238 981,087 77,589 37,050 114,639 150,000 77,238 227,238
Endowment funds 2021 £ - 171,210 - 171,210 - - - - - -
Unrestricted funds designated 2021 £ 33,350 - - 33,350 33,350 - 33,350 - - -
Unrestricted funds general 2021 £ 81,289 468,000 227,238 776,527 44,239 37,050 81,289 150,000 77,238 227,238
Donatons and legacies Donatons and gifs Legacies receivable Grants received Donatons and gifs Donatons Services in kind (ofce space) Grants receivable for core actvites The Sackler Trust Government grant - CJRS
3

GENESIS RESEARCH TRUST

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)

FOR THE YEAR ENDED 31 JULY 2021

4 Charitable actvites
Unrestricted
Unrestricted
funds funds
2021 2020
£ £
Symposium Programme 113,978 431,279
5 Fundraising actvites
Unrestricted Unrestricted
funds funds
general general
2021 2020
£ £
Fundraising events 4,782 42,860
6 Investments
Unrestricted Restricted Total Unrestricted
funds funds funds
general general
2021 2021 2021 2020
£ £ £ £
Income from listed investments 71,955 6,803 78,758 76,030
Interest receivable 25 - 25 141
71,980 6,803 78,783 76,171

GENESIS RESEARCH TRUST

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)

FOR THE YEAR ENDED 31 JULY 2021

7 Raising funds

Unrestricted
Endowment
funds
funds
general
2021
2021
£
£
Fundraising and publicity
Consultancy and other fundraising costs
6,738
-
Fundraising event costs
5,089
-
Staf costs
110,666
-
Support costs
71,374
-
Fundraising and publicity
193,867
-
Investment management
26,383
42,999
220,250
42,999
Total
Unrestricted
funds
general
2021
2020
£
£
6,738
82,670
5,089
45,187
110,666
87,474
71,374
43,324
193,867
258,655
69,382
27,258
263,249
285,913
Total
Unrestricted
funds
general
2021
2020
£
£
6,738
82,670
5,089
45,187
110,666
87,474
71,374
43,324
193,867
258,655
69,382
27,258
263,249
285,913
258,655
27,258
285,913

8 Charitable activities

Symposium
Programme
Medical
Research
Programme
2021
2021
£
£
Staf costs
59,403
-
Conferences, travel,
accommodaton & lecture fees
31,921
-
Other costs
-
63,496
91,324
63,496
Grant funding of actvites (see
note 9)
-
227,371
Share of support costs (see
note 10)
238,938
-
Share of governance costs (see
note 10)
-
18,450
330,262
309,317
Analysis by fund
Unrestricted funds - general
330,262
245,821
Designated funds
-
63,496
330,262
309,317
Total
2021
Symposium
Programme
Medical
Research
Programme
2020
2020
£
£
£
59,403
74,132
-
31,921
258,335
-
63,496
41,213
55,957
154,820
373,680
55,957
227,371
-
-
238,938
135,308
97,982
18,450
20,231
20,231
639,579
529,219
174,170
576,083
529,219
118,213
63,496
-
55,957
639,579
529,219
174,170
Total
2020
£
74,132
258,335
97,170
429,637
-
233,290
40,462
703,389
647,432
55,957
703,389

GENESIS RESEARCH TRUST

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)

FOR THE YEAR ENDED 31 JULY 2021

9 Grants payable

Medical
2020
Research
Programme
2021
£ £
Grants to insttutons:
Imperial College 227,371 -

10 Support costs

Support costs
Governance
costs
£
£
Staf costs
96,112
-
Depreciaton
1,471
-
Premises & equipment costs
45,430
-
Legal & professional costs
155,138
-
Other costs
12,161
-
Audit fees
-
13,450
Accountancy
-
5,000
310,312
18,450
Analysed between
Fundraising
71,374
-
Charitable actvites
238,938
18,450
310,312
18,450
2021
Support costs
Governance
costs
£
£
£
96,112
168,125
-
1,471
2,449
-
45,430
57,052
-
155,138
32,636
-
12,161
16,352
-
13,450
-
28,322
5,000
-
12,140
328,762
276,614
40,462
71,374
43,324
-
257,388
233,290
40,462
328,762
276,614
40,462
2020
£
168,125
2,449
57,052
32,636
16,352
28,322
12,140
317,076
43,324
273,752
317,076

Governance costs includes payments to the auditors of £13,450 (2020: £28,322) for audit fees and £5,000 (2020: £12,140) for statutory accounts assistance and general advice.

11 Trustees

None of the Trustees (or any persons connected with them) received any remuneration or benefits from the Trust during the year.

Key management personnel comprises the Trustees and Chief Executive. The total employee benefits of the eey management personnel of the charity were £36,591 (2020 : £89,763) which related to the Chief Executive.

GENESIS RESEARCH TRUST

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED) FOR THE YEAR ENDED 31 JULY 2021

12 Employees

The average monthly number of employees during the year was:

Direct charitable wore
Administratve wore
Total
Employment costs
Wages and salaries
Social security costs
Other pension costs
2021
Number
4
5
9
2021
£
246,111
16,763
3,307
266,181
2020
Number
6
4
10
2020
£
296,055
29,059
4,617
329,731

Wages and salaries include termination payments totalling £37,500.

The number of employees whose annual remuneration was £60,000 or more were:

£80,000 - £90,000
13
Net gains/(losses) on investments
2021
Number
-
2020
Number
1
Unrestricted
Endowment
funds
funds
general
2021
2021
£
£
Revaluaton of investments
442,209
46,914
Gain/(loss) on sale of investments
97,815
-
540,024
46,914
Total
Unrestricted
funds
general
2021
2020
£
£
489,123
163,870
97,815
47,028
586,938
210,898
Total
Unrestricted
funds
general
2021
2020
£
£
489,123
163,870
97,815
47,028
586,938
210,898
210,898

14 Transfers

Transfers between funds in the prior year represent the release and adjustments of designated funds.

GENESIS RESEARCH TRUST

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)

FOR THE YEAR ENDED 31 JULY 2021

15 Tangible fixed assets

Cost
At 1 August 2020
At 31 July 2021
Depreciaton and impairment
At 1 August 2020
Depreciaton charged in the year
At 31 July 2021
Carrying amount
At 31 July 2021
At 31 July 2020
Computers
£
4,413
4,413
2,449
1,471
3,920
493
1,964

16 Fixed asset investments

Listed
Commodites Cash in portolio
£
£
£
Cost or valuaton
At 1 August 2020
3,400,970
-
103,310
Additons
2,157,487
94,943
(2,252,430)
Valuaton changes
489,123
-
-
Funding of portolio
-
-
2,302,593
Interest
-
-
78,758
Investment management fees
-
-
(69,382)
Disposals
(1,202,350)
-
1,300,165
At 31 July 2021
4,845,230
94,943
1,463,014
Carrying amount
At 31 July 2021
4,845,230
94,943
1,463,014
At 31 July 2020
3,400,970
-
103,310
Total
£
3,504,280
-
489,123
2,302,593
78,758
(69,382
97,815
6,403,187
6,403,187
3,504,280

17 Financial instruments

Financial instruments 2021 2020
£ £
Carrying amount of fnancial assets
Instruments measured at fair value through proft or loss 4,845,230 3,400,970

GENESIS RESEARCH TRUST

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)

FOR THE YEAR ENDED 31 JULY 2021

18
Debtors
Amounts falling due within one year:
Other debtors
Prepayments and accrued income
19
Current asset investments
Propertes held for sale
20
Creditors: amounts falling due within one year
Notes
Deferred income
21
Trade creditors
Grants payable
Accruals
21
Deferred income
Other deferred income
2021
£
-
228,020
228,020
2021
£
-
2021
£
40,061
139,628
319,702
111,132
610,523
2021
£
40,061
2020
£
7,573
32,629
40,202
2020
£
1,558,297
2020
£
25,265
146,853
232,505
62,243
466,866
2020
£
25,265

During 2021, £25,265 (2020: £75,985) of deferred income was released in the year. Income is deferred in relation to events that are to be held in a future period.

22 Retirement benefit schemes

Defined contribution schemes

The Trust operates a defined contribution pension scheme for all qualifying employees. The assets of the scheme are held separately from those of the Trust in an independently administered fund.

The charge to profit or loss in respect of defined contribution schemes was £3,307 (2020 - £4,617).

Endowment funds Endowment funds represent assets which must be held permanently by the Trust. Income arising on the endowment funds can be used in accordance with the objects of the Trust and is included as restricted income. Any capital gains or losses arising on the assets form part of the fund. Movement in funds
Movement in funds
Balance at
Incoming
Resources
Transfers
Revaluatons
Balance at
Incoming
Resources
Transfers
Revaluatons
Balance at
1 August 2019
resources
expended
gains and losses
1 August 2020
resources
expended
gains and losses
31 July 2021
£
£
£
£
£
£
£
£
£
£
£
Permanent endowments Angela Patman scholarships fund
-
2,045,159
-
-
-
2,045,159
171,210
(42,999)
-
46,914
2,220,284
-
2,045,159
-
-
-
2,045,159
171,210
(42,999)
-
46,914
2,220,284
The Angela Patman scholarships fund: A permanent endowment gif (Angela Patman Scholarship Trust - APST) of £2,045,159 (net of expenses) was received by the Trust during the prior year. A further sum received in 2021 represents the adjustment for the fnal selling prices of the propertes lef under the Will. Expenditure of £42,999 represents costs in respect of the sale of the propertes that were borne by the Trust. The Trust will follow the wishes of the late Setlor which were as follows: "To promote the further educaton of students of limited fnancial means studying at The Imperial College School of Medicine (the “College”) (or any successor insttuton should the College merge with another insttuton or otherwise cease to exist) by the award which shall be at their discreton of one bursary per annum in full or part consideraton of the fees required for the study of medicine at the College together or to cover or partly cover the living and other expenses of such students." The Trustees have decided to apply a total return on investment approach in respect of establishing the amount of funds available. The trusteeship of the APST was transferred to the Trust by a Charity Commission Scheme dated 24 March 2020. The Commission also issued a directon to link the APST with the Trust for accountng and charity registraton purposes. The Trust is the sole trustee of the APST and can account for APST within GRT’s accounts however, the APST remains a separate linked charity ( Charity number: 1179130-1).
23

GENESIS RESEARCH TRUST

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED) FOR THE YEAR ENDED 31 JULY 2021

24 Restricted funds

The income funds of the charity include restricted funds comprising the following unexpended balances of donations and grants held on trust for specific purposes:

Movement in Movement in
funds funds
Balance at Incoming Balance at Incoming Balance at
1 August 2019 resources 1 August 2020 resources 31 July 2021
£ £ £ £ £
Angela Patman Scholarships - - - 6,803 6,803
Pre-term Labour Research 61,676 - 61,676 - 61,676
Prostrate Cancer Research 26,090 - 26,090 - 26,090
Ultrasound 3,005 - 3,005 - 3,005
90,771 - 90,771 6,803 97,574

The restricted funds represent amounts received by the charity for specific purposes as shown below:

Angela Pattman Scholarships: Income generated by the endowment fund as detailed in note 23.

Premises Fund : represents amounts received for premises.

Pre-term Labour Research Fund : represents specific research funds received from Observa Pharmaceutical Company.

Prostate Cancer Research Fund : represents funds provided for the specific work carried out by Professor I Huhtaniemi into the research of prostate cancer.

Ultrasound Fund : The award was made in 2017 to buy an ultrasound equipment. There has been no movement since 2017.

Designated funds The income funds of the charity include the following designated funds which have been set aside out of unrestricted funds by the trustees for specifc purposes: Movement in funds
Movement in funds
Balance at
Incoming
Resources
Transfers
Balance at
Incoming
Resources
Balance at
1 August 2019
resources
expended
1 August 2020
resources
expended
31 July 2021
£
£
£
£
£
£
£
£
Miscellaneous Amenity Funds
538,119
34,600
(55,957)
42,525
559,287
33,350
(63,496)
529,141
Teaching Fund
82,775
-
-
(82,775)
-
-
-
-
Research Fund
14,524
-
-
(14,524)
-
-
-
-
Miscellaneous Research Grants
176,551
-
-
(104,929)
71,622
-
-
71,622
811,969
34,600
(55,957)
(159,703)
630,909
33,350
(63,496)
600,763
Miscellaneous Amenity Funds: represent funds set aside for Research grants, symposium and travel cost to the symposiums Teaching Fund: represent funds set up for the teaching of PHD students at Imperial College NHS Trust. Research Funds: represent funds set aside for medical research. Miscellaneous Research Grants: represent standard grants given to Imperial. The grants are generally for a 3 year period. No new grants have been issued during the year so the grants will fnish on or before 31 July 2021. During both 2020 and 2021 awards were closed and these are shown as net write-backs above.
25

Total 2020 £ 1,964 3,504,280 1,724,075 5,230,319
Endowment funds 2020 £ - - 2,045,159 2,045,159
Restricted funds 2020 £ - 90,771 - 90,771
Designated funds 2020 £ - 630,909 - 630,909
Unrestricted funds 2020 £ 1,964 2,782,600 (321,084) 2,463,480
Total 2021 £ 493 6,403,187 (310,621) 6,093,059
Endowment funds 2021 £ - 2,220,284 - 2,220,284
Restricted funds 2021 £ - 97,574 - 97,574
Designated funds 2021 £ - 600,763 - 600,763
Analysis of net assets between funds Unrestricted funds 2021 £ Fund balances at 31 July 2021 are represented by: Tangible assets
493
Investments
3,484,566
Current assets/(liabilites)
(310,621)
3,174,438
26

GENESIS RESEARCH TRUST

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED) FOR THE YEAR ENDED 31 JULY 2021

27 Related party transactions

During the year donations totalling £nil (2020 - £10,000) were received from various Trustees and Trusts in which some of the Trustees of Genesis Research Trust were also Trustees. No conditions were attached to these donations.

Investment management fees of £26,383 (2020 : £27,258) have been paid to Veritas Investment Management (UK) Limited, a company in which one of the Trustees, Mr A S Rosenfelder, has a participating interest. Mr Rosenfelder is not involved in the management of the investments as he is not registered by the FCA in the UK.

During the year, grants totalling £227,371 (2020: £nil) were made to Imperial College where Professor P R Bennett is Director of IRDB and Professor S Franks is Professor of Reproductive Endocrinology.

No trustee received remuneration in the year.

28
Cash generated from operatons
Surplus for the year
Adjustments for:
Investment income recognised in statement of fnancial actvites
Investment management charged to portolio
Gain on disposal of investments
Fair value gains and losses on investments
Depreciaton and impairment of tangible fxed assets
Movements in working capital:
Decrease/(increase) in short term investments
(Increase)/decrease in debtors
Increase/(decrease) in creditors
Increase/(decrease) in deferred income
Cash generated from/(absorbed by) operatons
2021
2020
£
£
862,740
1,913,439
(78,783)
(76,171)
69,382
27,258
(97,815)
(47,028)
(489,123)
(163,870)
1,471
2,449
1,558,297
(1,558,297)
(187,818)
71,408
128,861
(262,766)
14,796
(75,985)
1,782,008
(169,563)
2021
2020
£
£
862,740
1,913,439
(78,783)
(76,171)
69,382
27,258
(97,815)
(47,028)
(489,123)
(163,870)
1,471
2,449
1,558,297
(1,558,297)
(187,818)
71,408
128,861
(262,766)
14,796
(75,985)
1,782,008
(169,563)
(169,563)

29 Analysis of changes in net funds The Trust had no debt during the year.