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2025-07-31-accounts

Charity no. 1176160

The Little Princess Trust Report and Audited Financial Statements 31 July 2025

The Little Princess Trust

Reference and administrative details

Reference and administrative details Reference and administrative details
For the year ended 31 July 2025
Charity number 1176160
Registered office and The Hannah Tarplee Building
operational address 22-25 Berrington Street
Hereford
Herefordshire
HR4 0BJ
Trustees The trustees who served during the year and up to the date of this report
were as follows:
Timothy Wheeler, Chair
Emma Corbett
Alison Goodwin
Timothy Lowe
Dr Francis Mussai resigned 1 July 2025
Caroline Shallow
Stuart Smith appointed 1 November 2025
Simon Tarplee
Mark Vickress
Richard Wells
Chief executive officer Philip Brace
Key management Philip Brace, Chief Executive Officer
personnel Adam Houchen, Head of Operations
Wendy Tarplee-Morris, Director of Services and Impact
Nadine Schofield, Finance Manager
Bankers NatWest
12 Broad Street
Hereford
HR4 9AH
Auditors Godfrey Wilson Limited
Chartered accountants and statutory auditors
5th Floor Mariner House
62 Prince Street
Bristol
BS1 4QD

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The Chair and Chief Executive Reflect on the Year

Anniversary helps us to reflect on all that has been achieved

As we mark the 20th year of The Little Princess Trust, this is a moment of both deep reflection and profound gratitude. This milestone is, above all, a tribute to Hannah, whose life, though heartbreakingly short, continues to inspire so much good in the world.

On June 3, 2005, Hannah passed away aged just five, having faced childhood cancer with incredible bravery. In the wake of such devastating loss, her parents, Simon and Wendy, responded not with anger or retreat, but with astonishing spirit and compassion. Out of their unimaginable grief, they inspired something extraordinary.

They never set out to build a charity. They simply wanted to honour Hannah, recognise with gratitude the support of a community that had been so generous with financial donations at a time of their loss, and ensure that other children facing cancer would never feel alone.

Today, two decades later, The Little Princess Trust stands as a beacon of hope and kindness, reaching thousands of young people with practical, emotional, and research-led support.

A legacy of kindness, a future of hope

Our core mission remains unchanged: to provide free, real-hair wigs to children and young people who lose their hair due to cancer treatment or other conditions—and to fund groundbreaking research into childhood cancers. Our reach has grown but so has the need.

This year, we have once again seen a significant rise in the demand for our wig service. More families than ever are turning to us for support. We are meeting that challenge with care, efficiency, and a commitment to the highest standards, ensuring that every wig we provide restores not just hair, but dignity and confidence too.

Our work in childhood cancer research has also evolved significantly. We are no longer just participants – we are established leaders. We now actively fund and help to shape some of the most exciting and impactful projects in the UK and beyond.

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Increasingly, we’re investing not only in studies but in the people and infrastructure that will be a part of progress for years to come: the researchers, clinicians, and facilities that turn lab discoveries into real world treatments.

A new home for our wigs

One of the most significant developments this year has been the purchase of a new building, a home designed specifically for the growing needs of the charity. This site will allow us to expand our services, support more families, and create a permanent hub for our incredible volunteers.

It will be a space where compassion meets action: a centre of excellence, a symbol of all we stand for, and a place of welcome, energy, and inspiration. It will be a space that our amazing volunteers will make their own and one in which they can clearly see the positive difference they help to make for children and young people with cancer.

As Wendy said recently, we don’t have all the answers, nor do we have a magic wand, but if we can ease the burden in a small way, then it’s worth doing and worth doing to the best of our ability.

Meeting the challenge

Of course, none of this is without challenge. Demand for our services continues to grow and with that comes pressure, on our systems, on governance and process, and on our people. But we are proud to say that we remain superbly organised, efficient, and focused on quality.

Whether it’s a wig, a research grant, or a message of encouragement, we do not settle for ‘good enough.’ We aim to be our best selves every single day. That’s only possible because of the extraordinary people who walk this journey with us.

To our wig recipients – you are our inspiration. Your strength motivates everything we do.

To our incredible supporters – your donations, your hair, your creativity and commitment lift us daily.

To our skilled and dedicated researchers – you give us hope for a world where no child is lost to cancer.

To our partner salons – we simply could not do this without your skill and compassion.

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To our brilliant team – you bring not just your talent, but your heart.

To our Trustees – thank you for your wisdom, your time, and your unwavering belief in our work.

To Simon and Wendy – thank you for transforming heartbreak into legacy, sorrow into strength, and Hannah’s story into a movement and legacy of love.

Looking ahead

In 2025, we commence a review of our research strategy of which will be shared in the second half of the fiscal year. This will include more grants and ‘New Ideas’ alongside the exciting work in continuing to encourage and facilitate real equality and collaboration. We want to be better and influence for the better.

As we look to the future, we do so with optimism and purpose. The Little Princess Trust will continue to grow, but we will never lose sight of our roots. Everything we do is built on care, community, and courage. Everything we achieve belongs to the children and families we serve.

Thank you to everyone who has been part of our journey so far. Together, we will keep being there for those who need us most. Together, we will honour Hannah’s legacy – not just for the next 20 years, but for generations to come.

With heartfelt thanks,

Tim Wheeler - Chair of Trustees

Philip Brace – CEO

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Objectives and Activities

The Little Princess Trust's primary objective is to provide real hair wigs, free of charge, to children and young people experiencing hair loss due to cancer treatment. The charity also provides wigs in the UK and Ireland to those who have experienced hair loss due to other conditions.

The charity will respond to ad-hoc requests for wigs that are received from children and young people in countries outside the UK where there is no service available. Meanwhile, formal partnerships have been established in Portugal, Sweden, Germany, Bulgaria, Slovenia and Iraq. The charity has links with salon representatives who liaise with hospitals to provide The Little Princess Trust’s wigs to children and young people in these six countries.

The Little Princess Trust has an extensive network of wig fitters and stylists across the UK and Ireland who offer a professional and compassionate service to each young person requesting a wig. The vast geographical reach allows the charity to put parents and carers in contact with wig fitters as local to them as possible to ensure the young person does not have to travel any further than necessary for their wig fitting.

Parents or carers can contact the charity themselves or, alternatively, the child's medical team can make the initial contact with The Little Princess Trust.

The charity arranges for the manufacture of its own range of wigs from donated hair. However, if the charity does not have a wig suitable for a child or young person with cancer, it will purchase one from a commercial supplier.

In addition to its wig provision service, The Little Princess Trust will fund research projects that will:

The charity engages with the Children and Young People’s Cancer Association (CCLG) to facilitate this process under guidelines from the Association of Medical Research Charities (AMRC).

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The Trustees have paid due regard to the Charity Commissioners' guidance on public benefit in deciding what activities are undertaken to further the charity's charitable purposes for the public benefit.

Achievements and Performance

The wig provision service

" For many people like me, the support The Little Princess Trust offers goes far beyond the beautiful wigs they provide free of charge. It is a lifeline, It is empowerment. For some, it is dignity.

“For me, the most valuable thing the charity gave me was the space to rebuild my self-image in my own time, and on my own terms.

“Wearing the wigs given to me by The Little Princess Trust helped me to regain my confidence and engage with the world while still grieving the loss of my hair and my appearance as I’d " known it.

Nell Dougherty

The number of children and young people that The Little Princess Trust helps each year through its free wig provision service has grown substantially over the past 20 years.

This increase, combined with the commitment to provide the very best wigs and the very best service, means that there are different groups of people involved to ensure the charity maintains its key aim and objective.

This includes the volunteers who sort thousands of hair donations, the talented wig knotters who spend up to 60 hours making each wig and the wig fitters who demonstrate great empathy and professionalism to style each wig as per the individual child’s request.

The requirement for an efficient logistical operation was highlighted by the charity receiving the highest number of wig referrals in its history. The figure of 2,169 wig referrals was up from the

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1,910 received in 2023/24 and higher than the previous record total of 1,931 in 2022/23.

Year Total number of wig referrals
2024/25 2,169
2023/24 1,910
2022/23 1,931
2021/22 1,747
2020/21 1,769
2019/20 1,614
2018/19 1,523

All figures cover a 12-month period from 1 August to 31 July.

While the charity does help young people with other hair loss conditions, its number one objective is to help those who have lost their hair through cancer treatment.

Most of the wig referrals received in the past year (65%) were from young people undergoing cancer treatment and once again highlighted the work carried out by the wig referrals team and the communications team in promoting the wig service in a variety of different channels.

The wig referrals team reviews feedback to guide its work and their findings showed that greater numbers of hospital staff are informing young patients of The Little Princess Trust’s wig provision service. A total of 614 wig referrals were the result of a hospital referral. The previous year was 478 – and the difference highlights the importance of the charity’s outreach representative who travels the country to visit hospital departments.

Another key objective is to provide wigs to children and young people of all genders. Efforts have been made by the wig referrals team to promote this message over several years and, with the support of the communications team, the number of male wig recipients rose from 160 to 195 over the past two years.

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While the charity’s key objective is to provide wigs to children in the UK and Ireland, support is given to young people in countries where there is no free wig provision service. Partnerships were previously established in countries such as Slovenia and Portugal to ensure wig fitters and stylists are working to our high standards to help children with hair loss in those countries.

The continual work with our partners overseas saw new links made to help children in Iraq while overall overseas referrals rose by 41%. The biggest increases were seen in Bulgaria and Sweden. In total, 112 wigs were provided to young people outside the UK and Ireland which equates to 5% of the overall wig referrals figure.

Wig gallery empowers young people with hair loss

The charity’s number one priority is always the health and wellbeing of its wig recipients. This has meant that the charity’s communications team has never made direct approaches to wig recipients to publicly promote The Little Princess Trust for marketing purposes.

On the few occasions that wig recipients have appeared in social media posts or in the traditional media, the initial request has always been made by the young person or their family.

However, staff at the charity were aware that some children may be happy to feature on The Little Princess Trust website if given the opportunity.

After much consideration, a carefully worded sentence was introduced to an email sent out by the wig referrals team explaining that the opportunity existed for children and young people to share photos of themselves wearing wigs on the charity’s website.

The new Wig Gallery was created and the hope is that the page will empower and support others facing hair loss while also giving them an idea of the kind of wigs that are freely available from the charity.

It must be stressed that photographs will only be displayed on the page once permission has been given from the wig recipient and, depending on their age, their parents.

Professional photographs help publicise free wig service

Professional photographs showing the quality and variety of the charity’s wigs were taken this year.

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The Little Princess Trust Report and Audited Financial Statements

The images, shot by Gabriella Karney, have already been used in social media posts, emailed newsletters and on the charity’s website to show young people the huge variety of wigs that are freely available to them.

It has been a long-held ambition of the charity’s communications department to add high-resolution images of the wigs to the picture library and the new photographs have also been published by newspapers as part of stories and features on the charity.

Guidelines changed on minimum hair lengths

The Little Princess Trust can only make its wigs thanks to the donations of hair it receives from its supporters.

The charity’s wigs come in a variety of colours and lengths, which means that there is a requirement to ensure incoming donations match the type of wigs being requested.

For many years, the charity has encouraged its supporters to donate hair that is at least 12 inches long as it has sought to fulfil the demand for its longer wigs. At the same time, it became clear that the charity had excellent levels of shorter hair donations being held in stock.

Following detailed discussions between the senior management team and the charity’s Trustees, the decision was taken to change the hair donation guidelines and specifically state that the minimum hair length being requested would rise from 7 inches to 10 inches.

Supporting Childhood Cancer Research

Charity’s reputation and influence continue to grow

The last year saw The Little Princess Trust commit many more millions of pounds to fund childhood cancer research.

Approving a total sum of £5,003,743 to fund scientists seeking to find kinder and more effective treatment once again underlined the importance of The Little Princess Trust to the UK’s childhood cancer research community.

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This was the fifth consecutive year that the charity has committed more than £5million to research and means that, since 2016 when The Little Princess Trust first began funding scientists, the total amount has surpassed £35 million while the total number of individual projects supported stands at 156.

Year Total given to childhood cancer research
2024/25 £5.0m
2023/24 £5.9m
2022/23 £6.6m
2021/22 £5.9m
2020/21 £5.8m

All figures cover a 12-month period from 1 August to 31 July.

A total of 17 individual research projects were funded in the past 12 months. Six of these were included in the charity’s New Ideas grants while the remaining 11 formed part of its 15[th] round of childhood cancer research funding.

Partnership with the University of Birmingham

On August 21, 2024, The Little Princess Trust signed an agreement with the University of Birmingham to fund a new Professorship at the University.

The £2 million commitment from the charity saw the creation of ‘The Little Princess Trust Chair of Paediatric Oncology’. This move strengthens the growing partnership between the charity and the university and reflects the shared vision for a future where no child suffers the devastating effects of cancer and its current treatments.

The first appointment to this significant new role is Professor Amos Burke, who has an extensive track record in paediatric cancer research, leadership and clinical innovation. His expertise and vision to lead on delivering clinical trials developing new treatment avenues for childhood cancers, aligns perfectly with the mission of The Little Princess Trust and the ambitions for this role.

Professor Burke said: “As the first holder of The Little Princess Trust Chair in Paediatric Oncology, I recognise the passion, commitment and vision of The Little Princess Trust that has led to the creation of this role and am grateful on behalf of the paediatric oncology community for this investment.

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“Working together, it is our hope that research will improve the outcomes for children with cancer in the UK and globally as well as paving the way for future advances by the next generations of holders of this role.”

The Little Princess Trust has previously invested in a substantial portfolio of children’s cancer research projects at the University of Birmingham, ranging from understanding the biology of childhood cancers including lymphomas and brain tumours to developing novel treatments by harnessing the immune system and improving diagnostic imaging through machine learning and artificial intelligence.

The Little Princess Trust has now provided close to £4million in research funding to the University of Birmingham and, in recognition of this support, the charity was inducted into the Chancellor's Guild of Benefactors, with its name inscribed into marble next to the Great Hall in the university’s Aston Webb building.

At a ceremony marking the inscription, Professor Karl Dearn, Head of the School of Engineering, said: “This partnership underscores The Little Princess Trust's truly transformative impact, not just on the individual lives, but on the broader medical landscape.

"Their work continues to shine as a source of hope, compassion and determination to make the world kinder, always striving for more and better treatments.”

Suitable candidate yet to be found for key Oxford position

While there was success in Birmingham with the appointment of Professor Burke, progress in identifying a suitable candidate to fill the professorial post of paediatric oncology at the University of Oxford has been slower than hoped.

Working with one of the oldest and most respected academic institutions in the world presents a significant opportunity to drive meaningful advancement in childhood cancer research.

Oxford continues to develop its vision for paediatric oncology, strengthening internal collaborations across immunology, genomics, data science, and translational medicine.

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The university is actively refining the scope of the professorial role to ensure it can attract exceptional global talent capable of leading a truly world-class programme with applications expected to be shortlisted for interview during December 2025.

During this period, the charity has remained closely engaged with Oxford’s senior leadership, contributing to strategic discussions and supporting efforts to align existing research strengths with future ambitions. There is clear momentum behind building a more unified and impactful paediatric oncology presence within the institution.

The aim, therefore, remains to help the university bring together its research programmes, enhance coordination across disciplines, and establish Oxford as a global centre of excellence in childhood cancer studies.

Research funded by charity published in highly-respected journal

A previously overlooked type of circular DNA may help explain why some children with leukaemia relapse, according to Little Princess Trust-funded research that was published in the highly-respect science journal, Nature.

The new paper reveals for the first time that DNA fragments called 'excised signal circles' (ESCs) can persist in cancer cells and may drive relapse in patients with B-cell precursor acute lymphoblastic leukaemia (BCP-ALL).

Lead author Dr Joan Boyes, from the University of Leeds, said: "It has been known for over 40 years that small circular chromosomes, known as 'double minutes', are present in many cancers in addition to normal chromosomes.

"A further type of circular DNA, known as ESCs, were thought to be lost soon after they form. But we discovered that ESCs replicate and persist, just like double minutes."

By tracking DNA patterns created when ESCs form, the researchers showed that the cells in which ESCs are present divide more frequently than other cancer cells.

They also showed that ESCs trigger mutations in cancer-causing genes, which can help to explain why high ESC levels lead to worse cancer outcomes.

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"We found, remarkably, that there are much higher levels of ESCs at diagnosis in many of the childhood leukaemia patients who are most likely to suffer relapse, compared to those who remain in remission," added Dr Boyes.

"Ultimately, this could help ensure that they are placed on the best treatments as soon as possible."

The Little Princess Trust contributed more than £250,000 to support the early and continued stages of Dr Boyes' research. Dr Boyes said: "We are extremely grateful to The Little Princess Trust, who funded this work from its earliest stages. Their continued funding enabled us to build on promising early experiments to expand the research further."

Appreciation for our support of experimental cancer centres

The Little Princess Trust has now completed the second year of its five-year funding commitment to the paediatric Experimental Cancer Medicine Centres (ECMC) network.

As part of this funding cycle, a number of objectives have been set and the charity’s key management personnel, along with the Programme Office team, are undertaking visits to all 12 paediatric ECMC sites across the UK.

The Little Princess Trust’s CEO and the charity’s Director of Service and Impact have accompanied ECMC on all site visits, ensuring the charity remains closely connected to the progress, challenges, and achievements at each centre.

These visits aim to understand each centre’s key achievements, identify challenges, and explore ‐ opportunities for further strengthening early phase research for children and young people with cancer.

Following each visit, the ECMC Programme Office prepares a summary and a set of recommended actions based on the findings. This process not only supports continuous improvement across the network but will also inform planning for the next funding period, due to commence in 2028.

Feedback from centres has been extremely positive, with many expressing appreciation for the opportunity to engage directly with funders, celebrate progress, and discuss areas where additional support could enhance the impact of their work.

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The Little Princess Trust will continue to be actively involved throughout the remainder of the funding cycle to help drive progress and ensure the best possible outcomes across the ECMC network.

Additional highlights from a successful year

Marking our 20[th] anniversary

The year 2025 marked the 20th anniversary of The Little Princess Trust. The communication team commemorated this special moment by looking at the charity’s impact and achievements over the past 20 years.

Logos were designed, templated copy was written, and other digital assets were created to help the charity and its supporters mark the milestone.

A great example of one business utilising the new assets came from Wahl who produced a limited edition LPT-branded hair dryer. The company donated £20 from every sale and used the newly-designed 20th anniversary branding on the reverse of the packaging to promote the charity.

Merchandise to promote the anniversary was also created to sell on the charity’s online shop. The artist, Lucy Claire, kindly gave up her time to create hand-drawn designs which were used on new T-shirts and mugs alongside the newly-created anniversary logos.

Royal recognition for charity co-founder

Wendy Tarplee-Morris, one of the co-founders of The Little Princess Trust, was awarded an MBE in the King's New Year Honours list in recognition of her services to children with cancer.

The Little Princess Trust was founded in memory of Wendy's daughter, Hannah Tarplee. In the first years of the charity, Wendy dedicated much of her time to lay the foundations of The Little Princess Trust and ensure the charity could grow and develop into what it is today.

Wendy has remained with the charity and, in her current role as Director of Service and Impact, ensures the young people with hair loss helped receive the very best service available.

She also jointly leads in the management of the charity’s research funding and dedicates great time and effort to make certain that The Little Princess Trust funds the very best scientific projects.

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New home purchased to store charity’s growing wig stock

As the charity supports a growing number of children and young people with its wigs, it has become apparent that increased storage capacity is needed to house a greater number of wigs.

The wigs have a high commercial value and, with a lack of remaining storage space inside the Hannah Tarplee Building, a new premises was purchased in Hereford city centre.

The building is situated very close to the charity’s existing premises and will mean staff can easily walk to and from the new site.

Planning permission is being sought to develop the site and create a new two-storey premises that, as well as housing the charity’s wigs, will also be an excellent working environment for the charity’s team of volunteers.

The volunteers perform important duties such as sorting incoming hair donations and making up fundraising packs.

Breathing new life into wig-making in the UK

The Little Princess Trust and leading wig manufacturer Banbury Postiche partnered to campaign for the establishment of a dedicated wig making apprenticeship in the UK.

The initiative aims to revitalise the craft, ensuring a new generation of skilled professionals can meet the growing demand for high-quality, handmade wigs.

With increasing reliance on overseas production, traditional wig making skills have dwindled in the UK. The proposed apprenticeship would provide structured training, equipping learners with the skills needed to make an increasing number of handmade wigs for individuals experiencing hair loss due to medical conditions.

The Little Princess Trust and Banbury Postiche first began a formal working partnership in 2020 when they helped to launch a UK wig making co-operative. The project sees freelance wig knotters receive training at Banbury Postiche’s headquarters in Oxfordshire before going on to make wigs for the children and young people using The Little Princess Trust’s free wig provision service.

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The success of the partnership, which saw its first wigs made in 2021, has provoked ideas to help increase the number of UK wigmakers further and led to the call for a dedicated wig making apprenticeship.

Praise from King Charles at Buckingham Palace

Representatives from The Little Princess Trust were invited to Buckingham Palace by HM King Charles for a special event for the cancer community.

In a heartfelt address to many people affected by cancer, King Charles spoke about his own diagnosis and how he’d become a cancer "statistic" - referencing the many cases recorded in the UK every day.

Praising the "community of care" of those who help cancer patients, for their humanity as well as their expertise, the King said his experience of living with cancer had shown that "the darkest moments of illness can be illuminated by the greatest compassion".

The Little Princess Trust was represented at the event by wig recipient and LPT Ambassador Kiya Kanani, Trustee Tim Lowe, Registered Health Play Specialist Penelope Hart-Spencer and Little Princess Trust Wig Referrals Manager Andrea Reese.

Hair donations confirmed as Guinness World Records

Two of the charity’s supporters achieved Guinness World Records titles for their epic hair donations.

Ruth Tripp’s hair touched the floor before she reached for the scissors while Jack Drever parted ways with his luscious locks after his first hair cut in seven years.

Ruth, a mum-of-four from Devon, donated 67 inches of hair while Jack, a 37-year-old builder from Southampton, gave 35 inches of his hair to the charity earning them the respective male and female Guiness World Records titles of largest single donation of hair by an individual.

Support from South Pole highlights charity’s reach

The breadth of the charity’s support was highlighted when hair was donated by four researchers in Antarctica. The meteorologists are based at the Rothera Research Station and took time away from their work to cut their long locks for The Little Princess Trust.

Hair has now been sent to the charity’s Hereford headquarters from people living in 128 different

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countries, proving that the support for The Little Princess Trust is truly global.

Funky Hair Funday goes international

The charity continues to promote fundraising through means that are not confined to sponsored hair donations and the Funky Hair Funday campaign remains popular with supporters.

Many schools and businesses in the UK have already styled their hair in imaginative ways to raise valuable funds and the profile of the charity’s work. This year, schoolchildren in Palmela, Portugal joined the fun and raised more than £800 for the charity in the process.

The event was organised after Helena Loureiro, a pupil at St Peter’s International School, suggested the idea. Priscila, Helena’s mother, said the day taught children lessons about the spirit of solidarity and showed them what can be achieved through active student participation.

Assembly packs help build links with primary schools

Children are understandably the key demographic for the charity and staff are always looking for ways to engage with this audience to ensure they know about the charity’s free wig service. The partnership with 1decision was started to explore ways to inform primary school pupils about the work of the charity and this link has been developed through the creation of assembly packs and lesson plans focused on the work of The Little Princess Trust.

Written and designed specifically for young children, more than 1,200 schools have accessed the free materials to use as part of their teaching. The digital kits, which were named as a finalist in the 2025 Teach Primary Awards, are designed to reduce anxiety and stigma surrounding the word cancer while promoting empathy, scientific understanding, and positive discussion within school communities.

VIP invite shows growing influence overseas

Evidence of the charity’s growing reputation overseas was in evidence on an emotional visit to Slovenia.

Phil Brace and Wendy Tarplee-Morris were invited to the National Conference Centre where they met the Slovenian President, Nataša Pirc Musar, and the Slovenian Prime Minister, Robert Golob.

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The British Ambassador and many other government ministers were also present at the Gold Ribbon Institute (Inštitut Zlata pentljica) event that saw children with cancer thank those who had supported them.

The Little Princess Trust has established partnerships in several countries to provide its wigs and Slovenia is among them. Mr Brace told those gathered in Ljubljana how the charity works with wig stylist Brigita Smrekar to help children with hair loss in Slovenia.

Importance of financial support from business community

While the majority of income is received through sponsored haircuts, it has been pleasing to see the amount of corporate support over the past 12 months.

One of the largest single donations came from Janus Henderson Investors, a global asset management company, who donated a five-figure sum to the charity. This contribution was made through the Janus Henderson Foundation and came about after Vicky Burdett, the company’s Marketing Executive, nominated The Little Princess Trust during her employer’s annual Charity Challenge.

Vicky was able to demonstrate to those deciding where the funding should go that the beliefs and values of Janus Henderson closely align with those of The Little Princess Trust.

Another sizeable donation came via the global real estate agency company, Colliers. Martyn Edwards, a Colliers employee and a stage 4 cancer survivor, was the main organiser of the Treasure Quest event that raised another five-figure contribution for the charity.

Martyn, who lost his hair when he underwent treatment, has now organised seven Treasure Quest events for The Little Princess Trust. Treasure Quest has been heavily supported by Colliers’ Birmingham office and the wider Midlands business community.

More long-term support has come from Sallys, the international retailer and distributor of professional beauty supplies. Sallys has now been a dedicated partner to The Little Princess Trust for more than a decade and raised more than £500,000 towards the charity’s Hair and Hope mission.

This huge financial sum has been donated from colleague fundraising and sales proceeds, but the support from Sallys goes beyond financial contributions and the company has also championed awareness of The Little Princess Trust’s free wig provision service to its customers.

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Salon Magazine, the UK’s leading publication for salon owners, also helped to raise the charity’s profile after giving The Little Princess Trust free editorial space to run a series of monthly features.

The full-page editorials ran for 12 months and provided an excellent platform for the charity to promote its service to hair industry professionals.

Future Plans

Be there for every young person with hair loss

While the charity will never set numerical targets for the number of wigs it provides each year, The Little Princess Trust will strive to make every young person with hair loss in the UK and Ireland aware that there is a free wig available for them.

Various departments and personnel within the charity will continue with this drive by visiting hospital departments, speaking to the traditional media and taking advantage of the charity’s social media presence to promote the free wig provision service.

Meanwhile, further moves will be made to expand the choices available to young people with hair loss by offering ‘toppers’ as an alternative to a full wig.

Commitment to fund research with greatest levels of impact

The charity remains committed to playing an increasingly important role in the funding of childhood cancer research in the UK.

The aim will be to repeat the support of previous years and a figure in excess of £7million has been set aside in The Little Princess Trust Childhood Cancer Research Fund for spending on research per the research strategy over the next five years.

Financial backing will be given through the charity’s annual research rounds while fact-finding visits will be made both in the UK and overseas by the key management personnel to ensure the best projects are funded that will bring about the greatest levels of impact.

A real expectation remains in place for the professorial post at the University of Oxford and what this can bring when a suitable candidate is found.

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New site presents exciting opportunities

The purchase of a new site less than 100 metres from The Little Princess Trust’s headquarters presents a wonderful opportunity for the charity to make significant developments.

Should planning permission be given, the extra space created by updating the two-storey building will ensure the charity can continue to increase the number of wig-knotters employed in Hereford and give a further boost to wig-making in the UK.

In addition to this, the new building will provide a safe and secure place to store the charity’s growing wig stock and allow for the creation of a new volunteer hub.

Those currently giving up their time to help the charity are based in two different buildings and the new premises will allow the charity to make a space dedicated to the volunteers and give greater recognition to their important role at The Little Princess Trust.

Address shortage of certain hair lengths

One objective which is a constant challenge to meet is ensuring there are sufficient numbers of all wig varieties in stock.

Certain colours and lengths can be more popular than others and the CRM system recently introduced offers an improved way to show where some hair types are lacking. Having an insufficient stock of a certain type of wig means that commercial wigs need to be bought to meet the wig request.

Historically, it has been a challenge to attract sufficient donations of long, blonde hair to meet demand for this type of wig. Social media has been utilised to promote the message for this type of hair but the charity will look to explore new options to help boost the number of lengthy blonde hair donations.

One idea to be explored is to liaise with a Scandinavian digital agency to see if certain geographical areas can be targeted with the charity’s messaging.

Mark a very special date in the charity's history

The year 2025 has been an important one in the life of the charity with many events already held to mark The Little Princess Trust’s 20th anniversary.

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Report and Audited Financial Statements

It is hoped that the campaign will continue to run throughout the final months of 2025 to not only raise the profile of the charity but bring in revenue, too.

Events scheduled to take place include an anniversary ball while it is hoped that the largest group of runners ever assembled will represent the charity at the Cardiff Half Marathon.

The governing documents that formally signalled the start of the charity were signed on November 12, 2005, and the communications team will be marking this date in 2025 to highlight The Little Princess Trust’s 20th birthday.

Financial Review

Financial overview of the year

Financial Results in Summary

Financial Results in Summary Financial Results in Summary
Actual 2024/5
Actual 2023/4
Total income 8,297,963
9,101,166
(8,192,314)
(9,078,637)
-
677,480
105,649
700,009
Total expenditure
Investment (losses) / income
Net (deficit) / surplus
Total funds at 31 July 16,340,898
16,253,249

Income

Total income for the year to 31 July 2025 was £8,297,963, a result that is a source of pride for all involved with the charity.

This figure sits closely alongside the previous year’s income of £9,101,166, in which the charity received an exceptional one-off government grant of £793,000 from the UK Government Post-Covid Recovery Medical Research Charity Support Fund.

When viewed without that extraordinary grant, this year’s income represents a truly outstanding achievement. It reflects the steadfast commitment of the charity’s supporters and the continued strength of its fundraising model, even during a period of wider economic uncertainty.

Excluding last year’s one-off grant, income this year demonstrates remarkable consistency and

21

The Little Princess Trust

Report and Audited Financial Statements

resilience. Despite ongoing economic challenges, the generosity of the charity’s community has remained unwavering, allowing The Little Princess Trust to continue its vital work for children and young people.

Sponsorship directly linked to hair donations continues to be the charity’s principal and most cherished source of income, a testament to the compassion, kindness, and dedication of those who choose to turn their haircut into a moment of hope.

Expenditure

The charity monitors spending closely and implements budgetary controls across the charity. Expenditure on charitable activities remained high at 88.7% of total expenditure (23/24 90.1%). We endeavour to keep the cost of raising funds to a minimum where possible.

The cost of raising funds was £929k compared to £897k in the prior year. This was mainly due to additional staff time spent on fundraising activities during the year compared to the prior year.

Overall, total expenditure for the year reduced from £9,078,637 in 23/24 to £8,192,314 in 24/25. Total expenditure includes research grants in year which are recognised in full at the date of the grant agreement. During the year, a total of £5,003,743 research grant funding was approved compared to £5,949,795 in 2023/24.

Fundraising activities

The Little Princess Trust maintains a consistently ethical, transparent, and responsible approach to all fundraising activities.

The charity is registered with the Fundraising Regulator and is an Organisational Member of the Institute of Fundraising. All staff adhere to the Code of Fundraising Practice, ensuring that the organisation meets sector-wide expectations of integrity and accountability.

The charity does not employ any external fundraisers and does not have full-time fundraising employees. The fundraising model is achieved by a highly valued community of generous hair donors whose sponsored haircuts account for nearly 90% of annual income.

This unique model isn’t just a funding mechanism it is the heart of the charity’s mission. Every individual who chooses to donate their hair transforms a personal moment into a powerful act of kindness, enabling the charity to provide real-hair wigs and vital research funding for children and young people.

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The Little Princess Trust

Report and Audited Financial Statements

The Little Princess Trust protects and honours this model with the utmost respect, ensuring that every contribution is valued and every donor’s impact is felt.

Unlike many organisations, the charity does not receive grants or government contracts; instead, the charity relies on the compassion, commitment, and creativity of the public.

Their support sustains the charity’s work, strengthens its independence, and empowers the charity to continue making a meaningful difference year after year.

The Board of Trustees oversees all fundraising activity. New initiatives and activities are reviewed and approved during board meetings held regularly throughout the year.

The Trustees are not aware of any instance in which the charity—or anyone acting on its behalf—failed to comply with recognised fundraising standards. Fundraising activity is monitored through online platforms, including JustGiving, enabling the charity to remain informed about supporter efforts. The charity aims to thank both hair donors and financial donors within 48 hours of being notified of their support.

No complaints regarding fundraising were received during the year ending 31 July 2025.

The charity is committed to protecting vulnerable people and the wider public from intrusive or pressurising fundraising practices. To ensure this, The Little Princess Trust:

The Trust does not approach members of the public directly for fundraising. Funds are raised through: individual donations; corporate supporters; and a small number of sporting and fundraising events.

This carefully controlled approach to fundraising underpins the charity’s long-standing commitment to remain low on overheads and high on impact, ensuring that the greatest possible proportion of income supports the charity’s core mission.

23

The Little Princess Trust Report and Audited Financial Statements

Reserves policy

The Trustees recognise the need to hold charitable funds as free reserves to safeguard the ability of the charity to continue to meet its charitable objectives. Free reserves are calculated as follows:

2025
£
2024
£
2025
£
2024
£
Total funds of the charity 16,340,898
16,235,249
(3,000)
(350,672)
(9,547,680)
(10,050,649)
(2,167,265)
(1,695,110)
Less: Restricted funds
Less: Designated funds
Less stock
Free Reserves 4,622,953
4,138,818

It is worth noting that although the charity appears to hold a significant amount of total funds, a significant part of these funds is either designated or restricted.

Free Reserves as a Percentage of Total Funds

----- Start of picture text -----
1%
13%
Designated
28% Free Reserves
58%
Stock
Restricted
----- End of picture text -----

After taking into consideration the risks faced by the charity and the potential impact of these risks on income and expenditure, The Little Princess Trust has a policy of maintaining sufficient free reserves to enable the charity to meet its operational expenditure (excluding research) for a period of between 12 and 24 months (£4m to £8m based on 2025/2026 budget).

This would enable the charity to continue to operate for a period of time should income become significantly impacted, and to allow time to assess and implement future plans.

24

The Little Princess Trust Report and Audited Financial Statements

The provision of a wig to a recipient can cover a significant period of time due to lengthy cancer treatment. It is therefore felt by the Trustees, that having free reserves available for a period of 12 to 24 months, would allow existing wig recipients to continue to have the support they need during treatment.

Excess reserves will be designated for specific activities by the Trustees when an appropriate and timely use of the funds has been identified and agreed by the Board.

At the end of 2024, there were designated funds to the value of £10m, and during the year, half of this was spent on research.

Free reserves as at 31 July 2025 amounted to £4.6m which is within the target range of the reserves policy. Each year, the Trustees review the reserves policy to ensure that it remains appropriate in the current environment.

At 31 July 2025, designated funds were represented by:

Restricted funds are those which can only be used for a particular purpose within the objects of the charity and when specified by the donor.

Restricted funds at 31 July 2025 were made up of:

Investment policy

To enable the charity to continue its wig provision and funding of research, it is vital that the charity receives a return on investments whilst protecting capital for future spending opportunities.

The Finance, Audit, Investment and Risk Committee (FAIRC) is responsible for overseeing the overall investment strategy and for the oversight of its implementation.

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The Little Princess Trust

Report and Audited Financial Statements

In the previous year, Trustees reviewed the charity’s investment strategy to assess the most appropriate means of balancing the need for access to funds in the short- to medium-term, with considerations of risk and return.

Following this review, in March 2024, the decision was made to liquidate the charity’s investment portfolios and instead place the funds in fixed-rate, short-term bank deposit accounts. This approach enabled the Charity to take advantage of high interest rates. It also provided a known rate of return, with low risk, while supporting access to funds in the short- to medium-term.

During the year, Trustees agreed to maintain this approach, and an updated Investment and Treasury Management Policy was approved. The policy aims to ensure that the charity manages cash resources efficiently to optimise financial returns, while safeguarding the charity’s interests by considering when access to funds may be needed, assessing and minimising risk and considering available interest rates.

In the year, investment returns in the form of interest on funds held in our bank accounts totalled £636,505.

Risk Management

Principal risks and uncertainties

As a charity, The Little Princess Trust faces risk in a wide range of areas, our principal strategic risks being:

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The Little Princess Trust

Report and Audited Financial Statements

Awareness of potential risk and appropriate mitigation actions is embedded at all levels within the organisation, supporting the culture of good risk management behaviours.

Recognising risk, escalating the risk where necessary, and taking appropriate and timely action ensures the charity acts robustly in its response to existing and emerging risks.

The responsibility for providing guidance to the Board on matters relating to risk is delegated to the CEO, who considers the subject of risk management in the wider context of charity management and governance.

Risks are identified, recorded in a risk register, and given ratings from low to high according to the likelihood of their occurrence and their impact should they occur.

The risk register is dynamic, showing movement in risk ratings between periods, and includes a traffic light system to illustrate confidence in the control.

The risk register is reviewed on a monthly basis and managed by Trustees to ensure that control measures in place are appropriate to mitigate each risk, with one Trustee appointed to lead on Audit and Risk Management.

Structure, Governance and Management

The Little Princess Trust was established in 2005 and became a registered charity (number 1113172) in March 2006. In December 2017, the charity was incorporated into a new Charitable Incorporated Organisation ('the new CIO' - registration number 1176160).

Effective from 1 August 2018, all the assets, liabilities and activities of the previous charity with the same name were transferred to the new CIO. The charity is governed by its Constitution as a charitable incorporated organisation (CIO), registered with the Charity Commission on 7 December 2017.

Organisational structure

The Board of Trustees is responsible for the overall governance of The Little Princess Trust and meet at least four times each year. The number of Trustees cannot be fewer than 3 or more than 12. If a vacancy arises, the trustees may appoint any eligible person as a Trustee.

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The Little Princess Trust

Report and Audited Financial Statements

New Trustees are appointed by a resolution of Trustees passed at a properly convened meeting. In selecting future Trustees, account is taken of the skills, knowledge and experience needed for the effective administration of the CIO.

All new Trustees are provided with an information pack including the Constitution and latest audited accounts. Each Trustee is given appropriate induction and training relevant to their responsibility. Trustees are also provided with regular briefings and information about relevant events.

The Trustee Board has established two sub-committees to provide advice, manage process, and deliver more detailed scrutiny of certain areas than is feasible and practicable within the Board's programme.

The Board receives regular reports on all aspects of the charity's work. The Board's powers of authority, remit and responsibilities delegated to these committees are defined in their respective Terms of Reference.

Whilst the Board has delegated authority to the committees to make certain decisions and to make recommendations for approval, the Board retains overall accountability, responsibility, and control.

Each committee is supported by trusted advisors who provide advice in their field of expertise on a probono basis. The terms of reference for these committees are summarised below.

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The Little Princess Trust

Report and Audited Financial Statements

Recruitment and appointment of new Trustees

There were no new Trustee appointments during the year and one Trustee, Dr Frank Mussai, left in the 12-month period.

Authority to conduct The Little Princess Trust's day-to-day activities is delegated to the Chief

Executive Officer, supported by the key management personnel named on page 1.

Remuneration policy for key management personnel

The Little Princess Trust pay review is based on a number of broad complexities. A benchmarking process of the external market is carried out which takes into account the economic environment and affordability for The Little Princess Trust.

The salary of the CEO is reviewed by a sub-committee of Trustees. This review includes a benchmarking process which takes account of both the local financial environment and the pay of CEOs within the charity sector, along with consideration of affordability for the charity and its overall salary range. The sub-committee then makes a recommendation to the Board of Trustees for ratification.

All Trustees give of their time freely and no Trustee received remuneration in the year in their capacity as a Trustee. Details of Trustees' expenses and related party transactions are disclosed in notes 9 and 22 to the accounts.

29

The Little Princess Trust Report and Audited Financial Statements

Statement of Trustees' Responsibilities

The Trustees are responsible for preparing the Trustees' report and the financial statements in accordance with applicable law and United Kingdom Accounting Standards, including Financial Reporting Standard 102: The Financial Reporting Standard applicable in the UK and the Republic of Ireland (United Kingdom Generally Accepted Accounting Practice).

The law applicable to charities in England and Wales requires the Trustees to prepare financial statements for each year which give a true and fair view of the state of affairs of the charity and of the incoming resources and application of resources of the charity for that period.

In preparing the financial statements, the Trustees are required to:

The Trustees are responsible for keeping proper accounting records that disclose with reasonable accuracy at any time the financial position of the charity and to enable them to ensure that the financial statements comply with the Charities Act 2011, the applicable Charities (Accounts and Reports) Regulations, and the provisions of the charity constitution.

They are also responsible for safeguarding the assets of the charity and taking reasonable steps for the prevention and detection of fraud and other irregularities.

The Trustees are responsible for the maintenance and integrity of the charity and financial information included on the charity's website. Legislation in the United Kingdom governing the preparation and dissemination of financial statements may differ from legislation in other jurisdictions.

Approved by order of the Board of Trustees on 24 January 2026 and signed on its behalf by:

Tim Wheeler- Chair of Trustees

30

Independent auditors' report

To the trustees of

The Little Princess Trust

Opinion

We have audited the financial statements of The Little Princess Trust (the 'charity') for the year ended 31 July 2025 which comprise the statement of financial activities, balance sheet, statement of cash flows and the related notes to the financial statements, including a summary of significant accounting policies. The financial reporting framework that has been applied in their preparation is applicable law and United Kingdom Accounting Standards, including Financial Reporting Standard 102: The Financial Reporting Standard applicable in the UK and Republic of Ireland (United Kingdom Generally Accepted Accounting Practice).

In our opinion, the financial statements:

▪have been prepared in accordance with the requirements of the Charities Act 2011.

Basis for opinion

We conducted our audit in accordance with International Standards on Auditing (UK) (ISAs (UK)) and applicable law. Our responsibilities under those standards are further described in the Auditor’s responsibilities for the audit of the financial statements section of our report. We are independent of the charity in accordance with the ethical requirements that are relevant to our audit of the financial statements in the UK, including the FRC’s Ethical Standard, and the provisions available for small entities, in the circumstances set out in note 9 to the financial statements, and we have fulfilled our other ethical responsibilities in accordance with these requirements. We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our opinion.

Conclusions relating to going concern

In auditing the financial statements, we have concluded that the trustees’ use of the going concern basis of accounting in the preparation of the financial statements is appropriate.

Based on the work we have performed, we have not identified any material uncertainties relating to events or conditions that, individually or collectively, may cast significant doubt on the charity's ability to continue as a going concern for a period of at least twelve months from when the financial statements are authorised for issue.

Our responsibilities and the responsibilities of the trustees with respect to going concern are described in the relevant sections of this report.

Other information

The other information comprises the information included in the annual report other than the financial statements and our auditor’s report thereon. The trustees are responsible for the other information. Our opinion on the financial statements does not cover the other information and we do not express any form of assurance conclusion thereon.

31

Independent auditors' report

To the trustees of

The Little Princess Trust

In connection with our audit of the financial statements, our responsibility is to read the other information and, in doing so, consider whether the other information is materially inconsistent with the financial statements or our knowledge obtained in the audit or otherwise appears to be materially misstated. If we identify such material inconsistencies or apparent material misstatements, we are required to determine whether there is a material misstatement in the financial statements or a material misstatement of the other information. If, based on the work we have performed, we conclude that there is a material misstatement of this other information, we are required to report that fact.

We have nothing to report in this regard.

Matters on which we are required to report by exception

We have nothing to report in respect of the following matters in relation to which the Charities (Accounts and Reports) Regulations 2008 require us to report to you if, in our opinion:

Responsibilities of the trustees

As explained more fully in the trustees’ responsibilities statement set out in the trustees’ report, the trustees are responsible for the preparation of the financial statements and for being satisfied that they give a true and fair view, and for such internal control as they determine is necessary to enable the preparation of financial statements that are free from material misstatement, whether due to fraud or error.

In preparing the financial statements, the trustees are responsible for assessing the charity’s ability to continue as a going concern, disclosing, as applicable, matters related to going concern and using the going concern basis of accounting unless the trustees either intend to liquidate the charity or to cease operations, or have no realistic alternative but to do so.

Our responsibilities for the audit of the financial statements

We have been appointed as auditor under section 144 of the Charities Act 2011 and report in accordance with the Act and relevant regulations made or having effect thereunder.

Our objectives are to obtain reasonable assurance about whether the financial statements as a whole are free from material misstatement, whether due to fraud or error, and to issue an auditor’s report that includes our opinion. Reasonable assurance is a high level of assurance, but is not a guarantee that an audit conducted in accordance with ISAs (UK) will always detect a material misstatement when it exists. Misstatements can arise from fraud or error and are considered material if, individually or in the aggregate, they could reasonably be expected to influence the economic decisions of users taken on the basis of these financial statements.

Irregularities, including fraud, are instances of non-compliance with laws and regulations. We design procedures in line with our responsibilities, outlined above, to detect material misstatements in respect of irregularities, including fraud. The procedures we carried out and the extent to which they are capable of detecting irregularities, including fraud, are detailed below:

32

Independent auditors' report

To the trustees of

The Little Princess Trust

(1) We obtained an understanding of the legal and regulatory framework that the charity operates in, and assessed the risk of non-compliance with applicable laws and regulations. Throughout the audit, we remained alert to possible indications of non-compliance.

(2) We reviewed the charity’s policies and procedures in relation to:

(3) We inspected the minutes of trustee meetings.

(4) We enquired about any non-routine communication with regulators and reviewed any reports made to them.

(5) We reviewed the financial statement disclosures and assessed their compliance with applicable laws and regulations.

(6) We performed analytical procedures to identify any unusual or unexpected transactions or balances that may indicate a risk of material fraud or error.

(7) We assessed the risk of fraud through management override of controls and carried out procedures to address this risk. Our procedures included:

Because of the inherent limitations of an audit, there is a risk that we will not detect all irregularities, including those leading to a material misstatement in the financial statements or non-compliance with regulation. Irregularities that arise due to fraud can be even harder to detect than those that arise from error as they may involve deliberate concealment or collusion.

A further description of our responsibilities for the audit of the financial statements is located on the Financial Reporting Council’s website at: www.frc.org.uk/auditorsresponsibilities. This description forms part of our auditor’s report.

33

Independent auditors' report

To the trustees of

The Little Princess Trust

Use of our report

This report is made solely to the charityʼs trustees, as a body, in accordance with Part 4 of the Charities (Accounts and Reports) Regulations 2008. Our audit work has been undertaken so that we might state to the charityʼs trustees those matters we are required to state to them in an auditorʼs report and for no other purpose. To the fullest extent permitted by law, we do not accept or assume responsibility to anyone other than the charity and the charityʼs trustees as a body, for our audit work, for this report, or for the opinions we have formed.

Godfrey Wilson Limited

Date: 24 January 2026

GODFREY WILSON LIMITED

Chartered accountants and statutory auditors 5th Floor Mariner House 62 Prince Street Bristol BS1 4QD

Godfrey Wilson Limited is eligible for appointment as auditor of the charity by virtue of its eligibility for appointment as auditor of a company under section 1212 of the Companies Act 2006.

34

The Little Princess Trust

Statement of financial activities

For the year ended 31 July 2025

Note
Income from:
Donations and legacies
3
Other trading activities
Investments
4
Other income
Total income
Expenditure on:
Raising funds
Charitable activities:
Wigs
Research
Total expenditure
6
Net gains / losses on investments
9
Reconciliation of funds:
Total funds brought forward
Total funds carried forward
Net income / (expenditure) and
net movement in funds
Restricted
£
23,000
-
-
-
23,000
-
10,000
360,672
370,672
-
(347,672)
350,672
3,000
Unrestricted
£
7,603,227
16,411
636,505
18,820
8,274,963
929,384
2,038,404
4,853,854
7,821,642
-
453,321
15,884,577
16,337,898
2025
2024
£
£
7,626,227
8,472,282
16,411
47,724
636,505
572,337
18,820
8,823
8,297,963
9,101,166
929,384
897,347
2,048,404
2,035,650
5,214,526
6,145,640
8,192,314
9,078,637
-
677,480
105,649
700,009
16,235,249
15,535,240
16,340,898
16,235,249

All of the above results are derived from continuing activities. There were no other recognised gains or losses other than those stated above. Movements in funds are disclosed in note 19 to the accounts.

35

The Little Princess Trust

Balance sheet

As at 31 July 2025

Note
Fixed assets
Tangible assets
12
Investments
13
Current assets
Stocks
14
Debtors
15
Current asset investments
Cash at bank and in hand
Liabilities
Creditors: amounts falling due within 1 year
16
Net current assets
Total assets less current liabilities
17
Net assets
18
Funds
19
Restricted funds
Unrestricted funds
Designated funds
General funds
Total charity funds
Creditors: amounts falling due after more
than 1 year
£
2,167,265
494,827
3,000,000
4,423,166
10,085,258
(4,720,789)
2025
£
2,194,292
10,500,000
12,694,292
5,364,469
18,058,761
(1,717,863)
16,340,898
3,000
9,547,680
6,790,218
16,340,898
2024
£
1,973,555
12,878,225
14,851,780
1,695,110
619,832
3,983,030
1,436,660
7,734,632
(4,690,691)
3,043,941
17,895,721
(1,660,472)
16,235,249
350,672
10,050,649
5,833,928
16,235,249

Approved by the trustees on 24 January 2026 and signed on their behalf by

Tim Wheeler - Chair

36

The Little Princess Trust

Statement of cash flows

For the year ended 31 July 2025

Note
Cash used in operating activities:
Net movement in funds
Adjustments for:
Depreciation charges
Net losses on disposal of assets
Losses on investments
Dividends, interest and rents from investments
Increase in stock
Decrease / (increase) in debtors
(Decrease) / increase in creditors
Net cash used in operating activities
Cash flows from investing activities:
Dividends, interest and rents from investments
Purchase of tangible fixed assets
Proceeds from the sale of investments
Purchase of investments
Net cash provided by investing activities
Increase / (decrease) in cash and cash equivalents in the year
Cash and cash equivalents at the beginning of the year
Cash and cash equivalents at the end of the year
Analysis of cash and cash equivalents
Cash at bank and in hand
Cash held in current asset investments
Cash held in fixed asset investments
13
2025
£
105,649
86,424
5,981
-
(636,505)
(472,155)
125,005
87,489
(698,112)
636,505
(313,142)
-
-
323,363
(374,749)
18,297,915
17,923,166
4,423,166
3,000,000
10,500,000
17,923,166
2024
£
700,009
106,105
-
(677,480)
(572,337)
(440,742)
(411,983)
(233,468)
(1,529,896)
572,337
(25,938)
13,426,485
(1,594,767)
12,378,117
10,848,221
7,449,694
18,297,915
1,436,660
3,983,030
12,878,225
18,297,915

The charity has not provided an analysis of changes in net debt as it does not have any long term financing arrangements.

37

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

1. Accounting policies

a) Basis of preparation

The Little Princess Trust is a Charitable Incorporated Organisation registered in England and Wales. The registered office address is:

The Hannah Tarplee Building 22-25 Berrington Street Hereford Herefordshire HR4 0BJ

The financial statements have been prepared in accordance with Accounting and Reporting by Charities: Statement of Recommended Practice applicable to charities in preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS 102) (effective 1 January 2019) - (Charities SORP (FRS 102)), the Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS 102).

The Little Princess Trust meets the definition of a public benefit entity under FRS 102. Assets and liabilities are initially recognised at historical cost or transaction value unless otherwise stated in the relevant accounting policy note.

b) Going concern basis of accounting

The accounts have been prepared on the assumption that the charity is able to continue as a going concern, which the trustees consider appropriate having regard to the current level of unrestricted reserves. There are no material uncertainties about the charity's ability to continue as a going concern.

c) Income

Income is recognised when the charity has entitlement to the funds, any performance conditions attached to the item of income have been met, it is probable that the income will be received and the amount can be measured reliably.

Donations income from fundraising platforms is recognised on receipt of the funds into the charity's bank account. The charity intends to recognise donations income from fundraising platforms on the date the gift is made when the systems are in place to facilitate this.

For legacies, entitlement is taken as the earlier of the date on which either: the charity is aware that probate has been granted, the estate has been finalised and notification has been made by the executor(s) to the Trust that a distribution will be made, or when a distribution is received from the estate. Receipt of a legacy, in whole or in part, is only considered probable when the amount can be measured reliably and the charity has been notified of the executor's intention to make a distribution. Where legacies have been notified to the charity, or the charity is aware of the granting of probate, and the criteria for income recognition have not been met, then the legacy is treated as a contingent asset and disclosed if material.

38

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

1. Accounting policies (continued)

d) Donated services and facilities

On receipt, donated professional services and donated facilities are recognised on the basis of the value of the gift to the charity which is the amount the charity would have been willing to pay to obtain services or facilities of equivalent economic benefit on the open market; a corresponding amount is then recognised in expenditure in the period of receipt.

e) Interest receivable

f) Funds accounting

Unrestricted funds are available to spend on activities that further any of the purposes of the charity. Designated funds are unrestricted funds of the charity which the trustees have decided at their discretion to set aside to use for a specific purpose. Restricted funds are donations which the donor has specified are to be solely used for particular areas of the charity's work or for specific projects being undertaken by the charity.

g) Expenditure and irrecoverable VAT

Expenditure is recognised once there is a legal or constructive obligation to make a payment to a third party, it is probable that settlement will be required and the amount of the obligation can be measured reliably.

Irrecoverable VAT is charged as a cost against the activity for which the expenditure was incurred.

h) Grants payable and grant commitments

Grants payable and grant commitments are recognised at the date the grant agreement is approved and signed by both the charity and the grant recipient. Grants are held at amortised cost using a cost of capital reflective of market risk.

39

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

1. Accounting policies (continued) i) Allocation of support and governance costs

2025 2024
Raising funds 31% 31%
Charitable activities - Wigs 61% 63%
Charitable activities - Research 8% 6%

j) Tangible fixed assets

Depreciation is provided at rates calculated to write down the cost of each asset to its estimated residual value over its expected useful life. The depreciation rates in use are as follows:

Freehold buildings 2% straight line
Computer equipment 33% straight line
Office equipment 33% straight line
Motor vehicles 33% straight line
Computer software 20% straight line
Plant and equipment 10% straight line

Items of equipment are capitalised where the purchase price exceeds £2,000.

k) Investments

Investments in quoted shares, traded bonds and similar investments are measured initially at cost and subsequently at fair value (their market value). The statement of financial activities includes the net gains and losses arising on revaluations and disposals throughout the year.

l) Stock

Stock is included at the lower of cost or net realisable value. Donated items of stock are recognised at fair value which is the amount the charity would have been willing to pay for the items on the open market. Donated hair is difficult to value in its raw state as it needs to go through a preparation process before it can be used in wig making.

m) Debtors

Trade and other debtors are recognised at the settlement amount due after any trade discount offered. Prepayments are valued at the amount prepaid net of any trade discounts due.

n) Current asset investments

Current asset investments consist of cash held on deposit in interest bearing accounts. Such investments are measured at their fair value.

o) Cash at bank and in hand

Cash at bank and cash in hand includes cash and short term highly liquid investments with a short maturity of three months or less from the date of acquisition or opening of the deposit or similar account.

40

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

1. Accounting policies (continued)

p) Creditors

Creditors and provisions are recognised where the charity has a present obligation resulting from a past event that will probably result in the transfer of funds to a third party and the amount due to settle the obligation can be measured or estimated reliably. Creditors and provisions are normally recognised at their settlement amount after allowing for any trade discounts due.

q) Financial instruments

The charity only has financial assets and financial liabilities of a kind that qualify as basic financial instruments. Basic financial instruments are initially recognised at transaction value and subsequently measured at their settlement value with the exception of bank loans, which are subsequently recognised at amortised cost using the effective interest method, and grants payable, which are held at amortised cost.

r) Pension costs

The charity operates a defined contribution pension scheme for its employees. There are no further liabilities other than that already recognised in the SOFA.

s) Foreign currency transactions

Transactions in foreign currencies are translated at rates prevailing at the date of the transaction. Balances denominated in foreign currencies are translated at the rate of exchange prevailing at the year end.

t) Accounting estimates and key judgements

In the application of the charity's accounting policies, the trustees are required to make judgements, estimates and assumptions about the carrying values of assets and liabilities that are not readily apparent from other sources. The estimates and underlying assumptions are based on historical experience and other factors that are considered to be relevant. Actual results may differ from these estimates.

The estimates and underlying assumptions are reviewed on an ongoing basis. Revisions to accounting estimates are recognised in the period in which the estimate is revised if the revision affects only that period, or in the period of the revision and future periods if the revision affects both current and future periods.

The key sources of estimation uncertainty that have a significant effect on the amounts recognised in the financial statements are depreciation (note 1j), the valuation of donated stock (note 1l) and the discount rate applied to long term grant payable commitments (note 1h).

41

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

2. Prior period comparatives: statement of financial activities

Income from:
Donations and legacies
Other trading activities
Investments
Other
Total income
Expenditure on:
Raising funds
Charitable activities
Wigs
Research
Total expenditure
Net gains on investments
3.
Income from donations and legacies
Donations
Legacies
Gift aid
Total from donations and legacies
Prior period comparative:
Donations

Gift aid
Net income and net movement in funds
Restricted
£
793,235
-
-
-
793,235
-
22,603
442,563
465,166
-
328,069
Restricted
£
13,000
10,000
-
23,000
Restricted
£
793,235
-
793,235
£
7,679,047
47,724
572,337
8,823
8,307,931
897,347
2,013,047
5,703,077
8,613,471
677,480
371,940
Unrestricted
£
6,496,310
-
1,106,917
7,603,227
Unrestricted
£
6,571,036
1,108,011
7,679,047
Unrestricted
2024
Total
£
8,472,282
47,724
572,337
8,823
9,101,166
897,347
2,035,650
6,145,640
9,078,637
677,480
700,009
Total 2025
£
6,509,310
10,000
1,106,917
7,626,227
Total 2024
£
7,364,271
1,108,011
8,472,282

42

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

For the year ended 31 July 2025
3.
Income from donations and legacies (continued)
*Included within donations are gifts in kind comprising:
Wigs and wig-related products
Wig fittings
Support for charity ball
Equipment
2025
88,736
2,080
-
76,169
166,985
2024
108,033
-
34,138
1,716
143,887

4. Income from investments

Income from investments
Treasury account interest
Dividends
Deposit account interest
Total from investments
2025
£
540,467
-
96,038
636,505
2024
£
267,584
179,037
125,716
572,337

All income from investments in the current and prior year was unrestricted.

5. Government grants

The charity did not receive any government grants in the current or prior year to fund charitable activities.

43

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

6. Total expenditure

Total expenditure
Wigs (cost of providing wigs incl carriage)
Research grants (note 7)
Staff costs (note 10)
Cost of fundraising events
Donation site fees
Merchandise
Accountancy, audit, legal and professional fees
Depreciation and loss on disposal
Equipment, IT and website costs
Heat, light, telephone and property costs
Marketing
Postage, printing, stationery and subscriptions
Travel, refreshments and sundry
Training
Sub-total
Allocation of support and governance costs
Total expenditure
Raising funds
£
-
-
208,055
76,439
236,099
151,392
-
-
-
-
-
-
-
-
671,985
257,399
929,384
Charitable
activities: Wigs
£
1,095,415
-
440,091
-
-
-
-
-
-
-
-
-
-
-
1,535,506
512,898
2,048,404
Charitable
activities:
Research
£
-
5,003,743
90,502
-
-
-
50,685
-
-
-
-
-
-
-
5,144,930
69,596
5,214,526
Support and
governance
costs
£
-
-
293,208
-
-
-
42,603
86,424
68,026
101,380
2,676
156,096
83,978
5,502
839,893
(839,893)
-
2025 Total
£
1,095,415
5,003,743
1,031,856
76,439
236,099
151,392
93,288
86,424
68,026
101,380
2,676
156,096
83,978
5,502
8,192,314
-
8,192,314

Total governance costs were £308,118 (2024: £267,166). This has increased in the year due to a change in focus of senior staff roles towards governance activities.

44

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

6. Total expenditure (continued) Prior period comparatives

Prior period comparatives
Wigs (cost of providing wigs incl carriage)
Research grants (note 7)
Staff costs (note 10)
Cost of fundraising events
Donation site fees
Merchandise
Investment management costs
Accountancy, audit, legal and professional fees
Depreciation and loss on disposal
Equipment, IT and website costs
Heat, light, telephone and property costs
Marketing
Postage, printing, stationery and subscriptions
Travel, refreshments and sundry
Training
Sub-total
Allocation of support and governance costs
Total expenditure
Raising funds
£
-
-
212,370
101,871
214,759
52,794
49,868
-
-
-
-
-
-
-
-
631,662
265,685
897,347
Charitable
activities: Wigs
£
1,036,108
-
453,693
-
-
-
-
-
-
-
-
-
-
-
-
1,489,801
545,849
2,035,650
Charitable
activities:
Research
£
-
5,949,795
90,364
-
-
-
-
52,618
-
-
-
-
-
-
-
6,092,777
52,863
6,145,640
Support and
governance
costs
£
-
-
252,976
-
-
-
-
36,279
106,105
76,264
84,199
6,136
209,849
71,349
21,240
864,397
(864,397)
-
2024 Total
£
1,036,108
5,949,795
1,009,403
101,871
214,759
52,794
49,868
88,897
106,105
76,264
84,199
6,136
209,849
71,349
21,240
9,078,637
-
9,078,637

45

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

7. Grants payable

During the year, 19 (2024: 17) new grants received approval to promote research into the causes of childhood cancers and into minimising the effects of chemotherapy on children.

Total grants committed to during the year were as follows:

Professorial post of Paediatric Oncology – Oxford University
Professorial post of Paediatric Oncology – Birmingham University
Children's Cancer and Leukaemia Group (CCLG)
Movement in effective discounting
Grants withdrawn from institutions
2025
£
-
2,000,000
3,074,380
9,685
(80,322)
5,003,743
2024
£
3,500,000
-
2,411,237
90,681
(52,123)
5,949,795

Allocation of support costs to grant making activities is given in note 6.

A breakdown of the research projects funded by the grants made to CCLG during the year is given in note 23.

8. Grant commitments

Grant commitments brought forward
Grants committed during the period (note 23)
Grants paid during the period
Grant commitments carried forward (notes 16 and 17)
2025
£
6,146,970
5,003,743
(4,912,342)
6,238,371
2024
£
6,379,940
5,949,795
(6,182,765)
6,146,970

9. Net movement in funds

This is stated after charging:

2025 2024
£ £
Depreciation and loss on disposal 86,424 106,105
Operating lease payments 2,224 888
Trustees' remuneration Nil Nil
Trustees' reimbursed expenses 491 784
Auditors' remuneration (excluding VAT):
Statutory audit 12,425 11,825
Other services 2,700 2,684

One trustee was reimbursed for expenses related to training, travel and sundry expenses (2024: 1 trustee reimbursed for training, travel and sundry expenses).

46

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

9. Net movement in funds (continued)

In common with other charities of our size and nature we use our auditors to assist with the preparation of the financial statements. Our auditors have also provided payroll services to the charity during the year.

10. Staff costs and numbers

Staff costs were as follows:

Salaries and wages
Social security costs
Pension costs
Employees earning more than £60,000 during the year:
Between £60,000 and £70,000
Between £70,000 and £80,000
Between £80,000 and £90,000
2025
£
920,586
86,199
25,071
1,031,856
2025
No.
1
-
1
2024
£
902,188
83,408
23,807
1,009,403
2024
No.
-
-
1

The key management personnel of the charity comprise the Chief Executive Officer, the Director of Services and Impact, the Head of Operations and the Finance Manager. The total employee benefits of the key management personnel were £282,196 (2024: Chief Executive Officer, Director of Services and Impact, Head of Operations: £266,269).

Average head count
Average full time equivalent
2025
No.
31
27
2024
No.
32
28

11. Taxation

The charity is exempt from corporation tax as all its income is charitable and is applied for charitable purposes.

47

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

12. Tangible fixed assets

Tangible fixed assets
Cost
At 1 August 2024
Additions in year
Disposals
At 31 July 2025
Depreciation
At 1 August 2024
Charge for the year
On disposal
At 31 July 2025
Net book value
At 31 July 2025
At 31 July 2024
£
1,970,556
309,381
-
2,279,937
122,567
39,411
-
161,978
2,117,959
1,847,989
Freehold
buildings
£
44,154
-
(4,061)
40,093
44,154
-
(4,061)
40,093
-
-
Computer
equipment
£
101,964
-
(3,163)
98,801
96,109
5,766
(3,162)
98,713
88
5,855
Office
equipment
£
61,396
-
(26,000)
35,396
27,731
19,546
(20,020)
27,257
8,139
33,665
Motor vehicles
£
105,285
3,761
-
109,046
24,271
21,120
-
45,391
63,655
81,014
Computer
software
£
5,807
-
-
5,807
775
581
-
1,356
4,451
5,032
Plant and
equipment
Total
£
2,289,162
313,142
(33,224)
2,569,080
315,607
86,424
(27,243)
374,788
2,194,292
1,973,555

48

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

13. Investments

Market value at 1 August
Additions
Disposals proceeds
Gains / (losses)
Movement in investment portfolio cash
Investment in fixed term deposit accounts
Market value at 31 July
Listed
investments
£
-
-
-
-
-
-
-
Cash
£
-
-
-
-
-
10,500,000
10,500,000
2025
£
-
-
-
-
-
10,500,000
10,500,000
2024
£
11,437,051
1,594,767
(13,426,485)
677,480
(282,813)
12,878,225
12,878,225

During the prior year, The Little Princess Trust closed its listed investment portfolio and desposited £12,878,225 in fixed term desposit accounts with a notice period of 365 days with the intention to hold these funds for greater than 12 months.

14. Stock

Wigs
Merchandise
Debtors
Trade debtors
Accrued income
Prepayments
Other debtors
Amount due after more than one year included above
2025
£
2,086,203
81,062
2,167,265
2025
£
7,093
385,801
101,885
48
494,827
48
2024
£
1,646,063
49,047
1,695,110
2024
£
-
534,317
84,895
620
619,832
620

15. Debtors

49

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

16. Creditors : amounts due within one year

Trade creditors
Grants payable
Other taxation and social security
Other creditors and accruals
Creditors: amounts due after more than one year
Grants payable
2025
£
120,807
4,520,508
19,553
59,921
4,720,789
2025
£
1,717,863
2024
£
131,812
4,486,498
19,370
53,011
4,690,691
2024
£
1,660,472

17. Creditors: amounts due after more than one year

18. Analysis of net assets between funds

Tangible fixed assets
Current assets
Current liabilities
Creditors falling due after one year
Net assets at 31 July 2025
Prior year comparative
Tangible fixed assets
Current assets
Current liabilities
Creditors falling due after one year
Net assets at 31 July 2024
Restricted
funds
£
-
3,000
-
-
3,000
Restricted
funds
£
-
350,672
-
-
350,672
£
12,694,292
3,091,759
(4,520,508)
(1,717,863)
9,547,680
£
14,851,780
1,345,839
(4,486,498)
(1,660,472)
10,050,649
Designated
funds
Designated
funds
General
funds
£
-
6,990,499
(200,281)
-
6,790,218
General
funds
£
-
6,038,121
(204,193)
-
5,833,928
Total funds
£
12,694,292
10,085,258
(4,720,789)
(1,717,863)
16,340,898
Total funds
£
14,851,780
7,734,632
(4,690,691)
(1,660,472)
16,235,249

50

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

19. Movements in funds

Covid Recovery Research Fund
Kilburn & Strode
The Grace Trust
PJ Legacy
Designated funds:
LPT Childhood Cancer Research Fund
Professorial post of Paediatric Oncology – Birmingham University
Fixed Asset Fund
Total designated funds
General funds
Total unrestricted funds
Total funds
Unrestricted funds
Restricted funds
Total restricted funds
£
350,672
-
-
-
350,672
6,077,094
2,000,000
1,973,555
10,050,649
5,833,928
15,884,577
16,235,249
At 1 August
2024
Income
£
-
10,000
3,000
10,000
23,000
4,000,000
-
-
4,000,000
4,274,963
8,274,963
8,297,963
£
£
(350,672)
-
(10,000)
-
-
-
(10,000)
-
(370,672)
-
(2,723,707)
-
(2,000,000)
-
(92,404)
313,142
(4,816,111)
313,142
(3,005,531)
(313,142)
(7,821,642)
-
(8,192,314)
-
Transfers
between funds
Expenditure
£
-
-
3,000
-
At 31 July
2025
3,000
7,353,387
-
2,194,293
9,547,680
6,790,218
16,337,898
16,340,898

51

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

19. Movements in funds (continued)

Prior year comparative
The Julia and Hans Rausing Trust
Covid Recovery Research Fund
Designated funds:
LPT Childhood Cancer Research Fund
Professorial post of Paediatric Oncology – Oxford University
Professorial post of Paediatric Oncology – Birmingham University
Fixed Asset Fund
Total designated funds
General funds
Total unrestricted funds
Total funds
Unrestricted funds
Restricted funds
Total restricted funds
£
22,603
-
22,603
5,000,000
3,500,000
-
2,053,722
10,553,722
4,958,915
15,512,637
15,535,240
At 1 August
2023
Income
£
-
793,235
793,235
-
-
-
-
-
8,307,931
8,307,931
9,101,166
£
(22,603)
(442,563)
(465,166)
(1,968,675)
(3,500,000)
-
(106,105)
(5,574,780)
(3,038,691)
(8,613,471)
(9,078,637)
Expenditure
£
£
-
-
-
-
-
-
-
3,045,769
-
-
-
2,000,000
-
25,938
-
5,071,707
677,480
(5,071,707)
677,480
-
677,480
-
Gains /
(losses)
Transfers
between funds
£
-
350,672
At 31 July
2024
350,672
6,077,094
-
2,000,000
1,973,555
10,050,649
5,833,928
15,884,577
16,235,249

52

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

19. Movements in funds (continued) Purposes of restricted funds

Covid Recovery Research Fund

This fund represents a grant from the UK Government Post Covid Recovery Medical Research Charity Support Fund. The funding aims to protect the pipeline of early career researchers and to help support the charity research sector regain its pre Covid level of research and innovation investment in the UK. The fund is intended to be used within a 12 month period to support spending on new research rounds.

Kilburn & Strode

A donation to contribute towards research in childhood cancers to be spent within 12 months.

The Grace Trust

A donation from The Grace Trust to assist with providing lighting, furniture & equipment for The Little Princess Trust’s in house wig knotters within 12 months.

PJ Legacy

A personal legacy of £10k made via HTL Solicitors on behalf of PJ, restricted for the funding of wig provision only.

Purposes of designated funds

LPT Childhood Cancer Research Fund

This fund is to enable the charity to fulfil its strategic research objectives and make research funding commitments spanning multiple years. The transfer has been made to increase the balance on the fund carried into 2025/26 to match the awards expected to be made in that year and future years.

– Professorial post of Paediatric Oncology Birmingham University

£2m was designated to gift to the University of Birmingham as an endowment which the University will use to fund a permanent professorial post of Paediatric Oncology.

Fixed Asset Fund

The fixed asset designated fund represents the total value of fixed assets held by the charity at the year ended 31 July 2025. Fixed asset additions are represented as transfers into the fund. Depreciation and loss on disposal of assets are represented as expenditure.

20. Financial instruments at fair value

Financial instruments at fair value
2025 2024
£ £
Financial assets measured at fair value - listed investments 10,500,000 12,878,225

53

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

21. Operating lease commitments

The charity had operating leases at the year end with total future minimum lease payments as follows:

Amount falling due:
Within 1 year
Within 1 - 5 years
2025
£
2,195
4,371
6,566
2024
£
1,907
636
2,543

22. Related party transactions

Caroline Shallow, a trustee, is Managing Director of R.H. Smith & Sons (Raoul Wigmakers) Limited (company number 01179968). During the year the charity made purchases of £111,881 (2024: £114,657) with Raoul Wigmakers. At the year end, the charity had amounts due to Raoul Wigmakers of £8,519 (2024: £12,720), which is included in trade creditors. All transactions were carried out at arms' length.

23. Research projects funded

The following grants were made via CCLG, which allowed the following research projects to be fully funded by The Little Princess Trust:

Institution
Purpose of grant
University College London
University of Surrey
ICR
University of Cambridge
Sub-total carried forward
Implementation of real-time fludarabine therapeutic drug
monitoring analysis in the UK for relapsed/refractory B-
cell acute ALL patients undergoing CAR T-cell therapy.
Protecting young hearts from drug induced cardiotoxicity.
SETting
the
stage
for
new
targeted
treatment
in
paediatric acute myeloid leukaemia.
Newcastle University
Optimising a two in one chimeric antigen receptor for
clinical translation in children's solid cancers.
Pharmacological
Protein
Degradation
of
Anaplastic
Lymphomas Kinase to treat Paediatric Cancer.
Newcastle University
Direct
in
vivo
interrogation
of
relapsed/refractory
Paediatric
B
cell
NHL
transcriptomics
and
clonal
evolution
via
lineage-tracing
focused
single
cell
sequencing.
Preclinical
testing
of
SMARCB1-dependent
synthetic
lethalities in MRT.
University College Cork
2025
£
4,950
264,501
250,080
309,592
197,661
299,858
298,256
1,624,898

54

The Little Princess Trust

Notes to the financial statements

For the year ended 31 July 2025

23. Research projects funded (continued)

Research projects funded (continued)
Sub-total brought forward
Institution
Purpose of grant
University of Bristol
University College Dublin
Imperial College London
University of Oxford
Imperial College London
Sub-total: grants made to CCLG
CCLG
Sub-total: grants made to CCLG less funds returned
Institution
Purpose of grant
University of Birmingham
Movement in effective discounting
Total grants payable
Targeting metabolism in aggressive childhood blood
cancers.
Gift to the University of Birmingham as an endowment
which the University will use to fund a permanent
professorial post of Paediatric Oncology.
Targeting
Radiation-Induced
Senescence
in
DMG:
Identification of Novel Cell Surface Markers.
Making a rapalog drug regulated OFF-switch CAR-T cell.
Combined underspends on research projects.
Some research grants approved in earlier years have been returned to the charity via
CCLG, as detailed below:
The following grants were paid directly to the institution:
University of Birmingham
Discovery and validation
of
FAM111A
inhibitors
for
cancers dependent upon the ALT-telomere pathway.
A
novel
targeted
drug
release
technology
for
the
treatment of paediatric glioma.
Spliceosome-Driven Neoepitopes: A New Approach for
Anti-tumour Immunity in HighRisk Neuroblastoma.
University College
London Ormond Street
Institute of Child Health
Twin-based models
for more effective treatment of
childhood leukaemia.
University of Nottingham
University of Nottingham
University College
London
Decoding
chemoresistance
in
osteosarcoma
using
lineage tracing and bone-mimetic models.
B7H3 immunotherapy in paediatric medulloblastoma.
Unlocking the potential of circulating small extracellular
vesicles
as
disease
biomarkers
for
paediatric
ependymoma.
Expanding the repertoire of spliceosome-targeting drugs
for childhood cancer treatment.
University College
London
2025
£
1,624,898
199,906
272,015
127,456
238,475
237,806
49,684
48,303
71,318
60,000
94,531
49,988
3,074,380
(80,322)
2,994,058
2,000,000
9,685
5,003,743

55