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||**Pages**|
|---|---|
|Trustees' annual report (incorporating the directors' report)|**1 to 6**|
|Independent auditor's report to the members|**7 to 10**|
|Statement of financial activities (including income and||
|expenditure account)|**11**|
|Statement of financial position|**12**|
|Statement of cash flows|**13**|
|Notes to the amended financial statements|**14 to 20**|





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|**Registered charity name**|Breakthrough Foundation|
|---|---|
|**Charity registration number**|1162536|
|**Company registration number**|09335387|
|**Principal office and registered**|4 Hill Street|
|**office**|London|
||W1J 5NE|



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|||B G J Gripton|(Retired 22 August 2022)|
|---|---|---|---|
|||Ms S Pavlova||
|||Mrs D A Forsdick|(Appointed 22 April 2021)|
|||R J Bonney|(Appointed 24 August 2022)|
|||C F J Chan|(Appointed 24 August 2022)|
|||J A Hutchinson|(Appointed 24 August 2022)|
|**Company **|**secretary**|Mrs D A Forsdick||
|**Auditor**||Critchleys Audit LLP||
|||Chartered Accountants & statutory auditor||
|||Beaver House||
|||23 −38 Hythe Bridge Street<br>Oxford||
|||OX1 2EP||
|**Bankers**||Credit Suisse AG||
|||Talacker 16,||
|||8001 Zurich,||
|||Switzerland; and||
|||1 Cabot Square, London E14 4QJ||
|**Solicitors**||Goodwin Procter LLP||
|||901 New York Avenue NW||
|||Washington DC 20001; and||
|||100 Cheapside||
|||London EC2V 6DY||





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|||**2020**|**2020**|2019|
|---|---|---|---|---|
|||**Unrestricted**|||
|||funds|**Total funds**|Total funds|
||**Note**|$|$|$|
|**Income and endowments**|||||
|Donations and legacies|**5**|36,519,000|**36,519,000**|35,000,000|
|Investment income|**6**|20,265|**20,265**|82,523|
|**Total income**||36,539,265|**36,539,265**|35,082,523|
|**Expenditure**|||||
|Expenditure on raising funds:|||||
|Costs of raising donations and legacies|**7**|53,537|**53,537**||
|Expenditure on charitable activities|**8,9**|35,825,540|**35,825,540**|27,680,061|
|**Total expenditure**||35,879,077|**35,879,077**|27,680,061|
|**Net income and net movement in funds**||660,188|**660,188**|7,402,462|
|**Reconciliation of funds**|||||
|Total funds brought forward||95,783|**95,783**|(7,306,679)|
|**Total funds carried forward**||755,971|**755,971**|95,783|





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|||2020|**2019**|
|---|---|---|---|
||Note|||
|**Fixed assets**||||
|**Investments**|15|10,000,000||
|**Current assets**||||
|**Cash at bank and in** hand||1,255,993|8,453,383|
|**Creditors: amounts falling due within one**year|17|**2,500,022**|**1,607,600**|
|**Net current assets/(liabilities)**||(1,244,029)|6,845,783|
|**Total assets less current liabilities**||**8,755,971**|**6,845,783**|
|**Creditors: amounts falling due after more than**||||
|**one year**|18|8,000,000|**6,750,000**|
|**Net assets**||755,971|**95,783**|
|**Funds of the charity**||||
|Unrestricted funds||755,971|95,783|
|**Total charity funds**|19|755,971|**95,783**|





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|**Year ended 31 Decembe**|**r 2020**|||
|---|---|---|---|
|||**2020**|2019|
||**Note**|$|$|
|**Cash flows from operating activities**||||
|**Net income**||**660,188**|**7,402,462**|
|_Adjustments for:_||||
|Dividends, interest and rents from investments||**(20,265)**|(82,523)|
|Accrued expenses/(income)||**2,142,422**|**(355,366)**|
|**Donation received** in−kind||**(10,000,000)**|**—**|
|_Changes in:_||||
|**Trade and other debtors**||**—**|**4,359**|
|**Trade and other creditors**||**—**|**(250,000)**|
|**Cash generated (used** in)/ from operations||**(7,217,655)**|**6,718,932**|
|**Net cash (used** in)/from operating activities||**(7,217,655)**|**6,718,932**|
|**Cash flows from investing activities**||||
|**Dividends, interest and rents from investments**||**20,265**|**82,523**|
|**Net cash** from investing activities||**20,265**|**82,523**|
|**Net (decrease)/increase in cash and cash equivalents**||**(7,197,390)**|6,801,455|
|**Cash and cash equivalents at beginning of year**||**8,453,383**|**1,651,928**|
|**Cash and cash equivalents at end of year**|**16**|**1,255,993**|**8,453,383**|





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|**5.**|**Donations and legacies**|||||
|---|---|---|---|---|---|
|||Unrestricted|**Total Funds**|Unrestricted|Total Funds|
|||Funds|**2020**|Funds|2019|
||**Donations**|||||
||Donations|36,519,000|**36,519,000**|35,000,000|35,000,000|
|**6.**|**Investment income**|||||
|||Unrestricted|**Total Funds**|Unrestricted|Total Funds|
|||Funds|**2020**|Funds|2019|
|||$|$|$|$|
||Income from cash investments|20,265|**20,265**|82,523|82,523|



||Unrestricted **Total Funds**|Unrestricted **Total Funds**|Unrestricted|Total Funds|
|---|---|---|---|---|
||Funds|**2020**|Funds|2019|
|Costs of raising donations and|||||
|legacies −Investment management<br>costs|53,537|**53,537**|||





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|**Expenditure on charitable**|**activities by fund type**||||
|---|---|---|---|---|
||Unrestricted|**Total Funds**|Unrestricted|Total Funds|
||Funds|**2020**|Funds|2019|
||$|$|$|$|
|Sponsorship|—|—|250,000|250,000|
|Donations|35,824,844|**35,824,844**|27,390,961|27,390,961|
|Bank charges|967|**967**|769|769|
|Support costs|(271)|**(271)**|38,331|38,331|
||35,825,540|**35,825,540**|27,680,061|27,680,061|



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|**Expenditure on charit**|**able activities by**|**activity type**|||||
|---|---|---|---|---|---|---|
||Activities||||||
||undertaken Grant funding||||**Total funds**|Total fund|
||directly|of activities Support|costs||**2020**|2019|
||$|$|$||$|$|
|Sponsorship|—|—||—|—|250,000|
|Donations|—|35,824,844||—|**35,824,844**|27,390,961|
|Bank charges|967|—|||**967**|769|
|Governance costs|—|—|(271)||**(271)**|38,331|
||967|35,824,844|(271)||**35,825,540**|27,680,061|



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|**Analysis of support costs**||||
|---|---|---|---|
||Analysis of|||
||support costs|||
||activity 1|**Total 2020**|Total 2019|
||$|$|$|
|Finance costs|(271)|**(271)**|(111)|
|Legal and professional fees|—|—|25,799|
|Travel expenses|—|—|12,643|
||(271)|**(271)**|38,331|





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|**11.**|**Analysis of grants**|||
|---|---|---|---|
|||**2020**|2019|
||**Grants to institutions**|||
||Breakthrough Prize Foundation|**21,446,000**|16,600,000|
||Breakthrough Prize in Life Sciences Foundation|**2,142,000**|9,694,208|
||Trustees of the University of Pennsylvania|**500,000**||
||Academy Foundation|**1,000,000**||
||Friends of Tel Aviv Sourasky Medical Centre|**1,000,000**||
||Los Angeles County Museum of Art||1,000,000|
||Magen David Adorn in Israel|**1,000,000**||
||Stanford University −Development Services<br>Keren Hayesod Jerusalem|**1,000,000**<br>**300,000**||
||University of Cambridge|**(3,612)**|(3,247)|
||The Foundation to Combat Anti−Semitism|**5,000,000**||
||Tel Aviv University|**1,000,000**||
||Beijing Xiaomi Foundation|**1,423,710**||
||Teach for America||100,000|
||Other|**16,746**||
|||**35,824,844**|27,390,961|
||Total grants|**35,824,844**|27,390,961|
|**12.**|**Net income**|||
||Net income is stated after charging/(crediting):|||
|||**2020**|2019|
||Foreign exchange differences|**(271)**|(111)|



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||**Other**|
|---|---|
||**investments**|
|**Cost or valuation**||
|At 1 January 2020||
|Additions|**10,000,000**|
|**At 31 December 2020**|**10,000,000**|
|**Impairment**||
|**At 1 January 2020 and 31 December 2020**||
|**Carrying amount**||
|**At 31 December 2020**|**10,000,000**|
|At 31 December 2019||



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|||**2020**|2019|
|---|---|---|---|
||Cash at bank and in hand|**1,255,993**|8,453,383|
|||**1,255,993**|8,453,383|
|**17.**|**Creditors: amounts falling due within one year**|||
|||**2020**|2019|
||Bank loans and overdrafts|**22**||
||Accrual for grants payable|**2,600,000**|1,607,600|
|||**2,600,022**|1,607,600|
|**18.**|**Creditors: amounts falling due after more than one year**|||
|||**2020**|2019|
||Accrual for grants payable|**8,000,000**|6,750,000|





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|**Unrestri**|**cted funds**|||||
|---|---|---|---|---|---|
|||At|||**At**|
|||1 January|||**31 December**|
|||2020|Income|Expenditure|**2020**|
|General|funds|95,783|36,539,265|(35,879,077)|**755,971**|
|||At|||At|
|||1 January|||31 December|
|||2019|Income|Expenditure|2019|
|General|funds|(7,306,679)|35,082,523|(27,680,061)|95,783|



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|**Analysis of net assets between funds**|||||
|---|---|---|---|---|
||||Unrestricted|**Total Funds**|
||||Funds|**2020**|
|Investments|||10,000,000|**10,000,000**|
|Current assets|||1,255,993|**1,255,993**|
|Creditors: amounts falling due within one year<br>Creditors: amounts falling due after more than one year|||(2,500,022)<br>(8,000,000)|**(8,000,022)**<br>**(2,500,000)**|
|**Net assets**|||755,971|**755,971**|
||||Unrestricted|Total Funds|
||||Funds|2019|
|Investments|||||
|Current assets|||8,453,383|8,453,383|
|Creditors: amounts falling due within one year<br>Creditors: amounts falling due after more than one year|||(1,607,600)<br>(6,750,000)|(1,607,600)<br>(6,750,000)|
|**Net assets**|||95,783|95,783|
|**Analysis of changes in net debt**|||||
||At|1 January||**At 31**|
|||2020|Cash flows|**December 2020**|
|Cash at bank and in hand|8,453,383||(7,197,390)|**1,255,993**|
|Bank overdrafts|||(22)|**(22)**|
||8,453,383||(7,197,412)|**1,255,971**|



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