Re￿s￿*￿ 1158189
KN¢f•iN AS
HlSno UK
ANI4UAL REpoftfAND UNALIDfiED FINANQAL sfATEMÉIIT5
FOR THE YEAR ENDED 31 AqAR¢H 2Q5

Hisnocyiosis UK
H15no UK
iEGAL AND AOMINisllIA￿ INFOAMAYION
Mr A Kontoyannis. Chalr
Pfr)l. P aeveFley
Dr V Nandurt
Mr P ￿enefi$tOCk
Prof. M Collin
Dr R fattersall
Oth•pOffl￿fS
Lynn Jaclson. Executive Olrector
Chartty number
1158789
p￿ndpa[ •ddr
PO Box 159
Liskeard
Q)rnwall
pu4 9DQ
Ind•wndent emmlnw
TC Group
33 805ton Road South
Holbeach
Spaldin8
UrKolnshlre
PE12 7LR
B4nk
CAF Hank UmSted
25 Ktnp Hlll Avenue
Kings. Hill West Malllni
Kent
ME194JQ

HJSTiocYf051S Lr
Hisno UK
CON7ENf5
Trn5tee5' report
Ststemomt of tnths. ￿spOnSIbl10t1es
Independ*nt eFamlnerfs report
Ststement of finanelal arti4*ile5
B¥tsnc• sh•ei
Notes ta the financral strtements
10-17

HISTiocYfosis UK
Hisrio ux
TrUSIEES' REPORT
FOR THE YEAR EPIDED 31 MAACH2025
The rrustiyes P￿sent thelr •llnual report and ftnanclal statements for the year ended 31 Math 2025.
Pml. C Booth on 31st Au8bJSt 2024
Oble¢li¥esand acd¥ltks
• The oblert ol ihe CIO Is Ihe reltef cl sickness and preser¥allon ol good h?alih amon8 patlents Jfferted
histlorytlc dlseases ihdr families and carets. In particular but fiot exclu51vely by:
111 the prDmotion and further4nce of sclentlllt rtsearth Into the phwlolory and patholoRY ol histloLytes Jnd
the JetiDlogy of histiocytoLytlc 015eases. thE Useful fesulrs of which will be dis5emln•ted for the publlc benefit,.
lill the devewmeni of more accuTrte means of dia8nosi5. improverj proiocols for managemert of ￿UeNts
and ulilmlrely measurÈs foi pre¥enrlon of N5tiWic dlsease5:
Iiril the pm¥isSon and dlmeminailon ol Informa￿0￿. edueatron and kn¢Mled&e in support ol Mlents and
firnllles aflKted by the disease to include the medlcal profe5slons and 8*neral publlr,
• Ilv) c¢llaboTrtlon wlih inten15t￿ Individuals •Trd OryanI￿tiOns.
The TrLtstees confim that they have ￿leffe￿ to the g￿ldIn(e ¢tsntained in the Charlty Commlsslon'$ 8enerydl
8uidanre on publlG benefft when rev￿wIng the ChaTIty's alrns and objectives and In plannin8 fulut* •ctivttle5
and Settl￿ the 8rant poucy forthe year.
The Charfty carries oui thvA obled￿*S by focusing on these ar*as Ihrou8h which we 4chkne our strate8iC
pdortzies ol mainlAlnlnB a stable ptoirarnmt and the CDntinued fundini of ¥btal researth. The bentllts ol ihe
Charity's work are the de¥elopmtnt ol future research. rhe dlssemlnatlon of rrfearch fimdlnKS. the
development of ftew therdple5 and the fvndlr¥ of 01tr804nB re5eaich wlth the 8oal belng able to Inlon
sufferers. their and lamil¢es.
Thp trustees CDnfim that Ihey have complled 7knh the r*qutrem•nts of sectlon 17 cf th• Charltl•s Act 2011
have tT8ard to tht publlc benelltguldance pvbltshed by the Chartty COMMIS￿On for E￿14Th￿ and Wales.
Flnafvdal Roport
The tharIL￿$ paliry * prtsent IS to Sn¥est In Iow-risk ond re450n¥bly Ilquld assets. so that fvnds are av•il*le to
rntet any unforeseen needs thai may arise, for eyample, as a consequ•nce af rpeetini athltles.
As lar as possible. the ChafiVI seeks to follow an ethical investment stftte8y that predudes Inv•$14n8 in any
company whose actlvltles fftay have an adverse Irnpatt on the underSylnB ben•fldath of the tharity, Whlle
striving for the hl8hest eihlcal srandartls. thE Charity wlll adhe￿ to the Charity COMMI￿on'5 rule th4t wt
mamimise the income of the charity withotst exptsstsr¢ to urtduè ris

H15no UK
TrusrB' REPOHT {CONTrNUED)
Fln4ndol rnbTew
The Chaim74Tr rtyularty ￿l￿W5 the rostr¥es of the chority to ensure ih•t suffident Ilquld fvnds a￿ a¥allable ro
the Charlty to meet its orwnl obliW5¢x6. The ￿SelVeS throughout the aC￿u￿)￿ perTrod have been
adequthto f4tlfll thls oblectlv•.
The 20E*21)25 Inrome st•ady 48aln# the p￿Qu$ nnanclal ￿ar. charl￿ are In generdl suffeflng
fmm the a7ntln¥ed d¢y*n￿rn In thE cost ol Ir4fn& ra151￿ onBoin8 concem5 about Ihe "o)st of Ki¥1￿. In th15
economlc cllmats.
We thank all ol our 8enero¢Js donor5. the Indlv5dyal4 communlty VDUPS. 5¢hook. corpordte ￿pPorterS,
Ch*ities and FoUnda￿an$ that ContInu￿ thelr support and ￿flects the excelleni partkipa￿On, driye and
iernslty of tsur c4fflrnuth lundtsh¢￿ supporters, fan4lle5 and t¢Anmitted Individuab tlwt been atAe
to us m•lntsln the Chaty.
H15tlo UK placed a call for Researth Paper5, after sub5tsntlal ievlew by the Suentlllc Revlew aoaTd and
rDnfim41ion of the Boa￿ of TFUS*es an awanl offer VAS mide to.. DT Clalre Shannon-Lowe and her team lor a
proiert to Undetstsnd ihe rDle of MWold derlvtd supprE55or ceus In the pathoIene5￿ of Epsttln Ba￿ vor￿$.
as%Kiat•d HLH.
Nll In the financlal year
Flnandal
R•lknlry on thts p•sr yw of 0￿￿tIOn, we acknowledBe ihe ￿pPOrt reeeived tn kn of funds •nd thq
contrfbutlons ol ¢wr VolUrfee￿ Ind Hisilo Clwllplon5. We recognlse t￿t the currnnt eoinomlc climate
affffts not only us but also Our MIAio Communlty and olhw5, makln8 It • chall￿￿n8 ￿rIOd for e¥eryfjno.
The Charity acknowledaej the Ilkelllwod of fEdu(ed IrK3)me for the futurE and contlftuts to adjust pftctlces and
budB•ts aca>rdir41y.
We ore very pleased to ha¥E continued and further dewtloped our various HtstFOCVtir infonhatlon guides and
50clal rn￿la platforn￿ 8llowlnK us tt4 tno44 fwther Wilh our Patients, PabTn15 and SupporteB.
In o)Habor4tlon with our panner5. * w41 malntslA our commltrnent io pmvxlln8 hlsEiocytic prpIe5￿o￿IS.
potlents. and families *ith the mort Sntsrniatlon re8ard4n8 these *rious and de￿￿$ d150rdef5 as il
becomes ovallable.
Thank you al.

HISTIOCYFOSIS UK
Hisno IJK
TrusrEE5' REpoirr Ici)IfflNUED)
R)R ThtE VEAR ENDED 31 MAROI 2025
Path•r5hlp5
Hlsuo UK prDiide5 webslte admiftthtive support to this am•iin8 group.
Hlstlo UK provides web51te admlni5tTrtlon 10 th15 eA•bli5hed re8lstry pro8rnm.
PPPIEPunel-P•Vert Pavert Publl¢lnvahcment a Enqaqemtnrponel
Histiotytosts UK Is committed to meaninglitl patlent and publK Itivolvement and publlc enlatement for and on
behall of not onty Its own Gftnl Fund Award5 but to appfdlse those of ulher Researchets and or Or¥an1￿tIOnS
in the field ol r•searth with prlorlty to tlia5e of H15tlocyti¢ d4se•se5.
Ourvi5ion wlih rer4rds to patl*nt. par•nt ond pubIk+n￿l¥ernent and en8agement I
"to esiablish • culiurn wlthln Hlstio¢ytosls iIK where our commuthty h•$ the 5ktlls Ind resources to optlm15e
and dellver patlent and publi¢ Involvoment and enzo&ement and It is inth8rnted In to our of worklnB afid
thrDU8hout the rnsearth we lund and app￿15•.
Hlstlocyt0515 UK hos, In tonsultation ￿th rn5eiir¢hers, publ1¢ ¢orttrfbuior5 and InbKsl¥tment professionals,
ideniffied 6 alms that wlll gvlde HistiOLytOSis UK and Fts •npymtnt proyamme tu work tQ¥Ydrds it's tytsto
that No one should die ol HistlQLytOSi5'.
Ensure our iesearth comrnunlty ihcorporaies pat￿t and publlc Involvement and enwement
throu8hoLrt Trseorch.
Intorpornte relwdnt Invofvement thra4haui our fundlw pr￿esses.
Lead by exarn￿e In our Invol¥ementand en8aBement pranice.
. SirpnKthen i￿1¥¥Ment and enpiement practic* of Histyo UK'S PJii*nL & Public In¥•h*rnenl
Eh8a8emÈrtt ￿ne1.
Insplre and encour38e Inclusi¥e. Innovatlve. di¥ets• and creall¥* paI￿nt, parent and pub15c
Involvement •rtd èn8a8ement.
Impn)ve the knowledge sharln8 olpatlent, Pa￿￿t and publlc invol¥ement arvl enptrm•nt.
The HS is the oryani5akn repiesenting clinkal and research prOfess￿Ra[$ in the Ileld of Hlstipcyllc d150rdtrs.
rh* Nlknlos5ymwslumon Hhtltxytasts
The Nlkolas Syrnposlum Is the leadln8 Scientif￿ think.tank fuaMd on a 8mup of rnTE d￿a$￿ <alled ￿￿10cVIk
dlsorders. This intern•tlonal research symp0￿￿MIS dedicated to foxerini InnmU4t fEs•arch.
Awareness
Awareness
HlstkrytDslJ UK202412025-g•teSk&Lets Tolk& Shqre yourltskr
Thi5 year we eKpandeLI our Shar* ￿ur Volce proram kn Incl¥de B6te-Sze efi4bliry HlxiD Proknionab and
Patients to share iheirexper6tnce and journey5.

Hisnocyyosis UK
Hlsllo UK
7RUs￿E￿ ftEPORr (co￿￿￿VED1
FOR ThEYEARWdDE031 MARCH2025
Phns fBrth• fufvrn
Htstlo UK remalns at th• forefront In chalen8ln8 these deV45tsu￿ dlsorfer4 WE wjll cuntlnue to bulld on the
transfer of Infvrmakn and knowled8e mllable n*t¥onallyand Inttrn•tiorollythmu8h our ojmmiltee strt¥cture
to par*nts. patients •nd medkal prole5sfionals.
StN¢ture, 6ty4ern•fte•4nd M•nayrnent
HlstloLfvls UK Is * r•Alrter•d charlty, nwnber 1158789. Ind Is constiiut*d as a charttable In￿rP￿rIte0
D￿nIs0t1¢￿ In England 4nd Wales.
Th• Ch•riry arti￿[V fundrals*s and seeks to continue the charitsble wor* dos}￿d by tho donol through the
¢arelul #ewanlshlp of Its exl#in8 resDurce*
At ih• ann￿￿ TTUStees' rneetsnK% the TA￿•*5 a8l*t th• brnad strath8y and IT￿ of xtivity for the Charity.
In¢[Ud5￿ COn￿d•￿tIon of 8rant m•Wn& 5n¥*stmenL reseThes and risk manayment pobicies and performan¢¢.
The da*to4ay admlnlsir4tlon of 8rnnts •nd the p1vc￿l￿8 ond ￿ndI￿n8 of ¥plkntlons prtor to coft$ldeTrllan
by the Charfty 55 *Jeltyted to the Ex•cutfve Olrertor.
Th• thartvs Ind*pendent Sdentifle Revlew Board consider èll applkatlons against a8roed trlterfa prfor to
maklry r•commendation to thE Charfty on fvndln8 8rdnt& The SR8 all oppllotions rttei¥ed In response
to calls for proposal&
Th• Ch•lr olthESR8 for Z024th1015. ￿￿¢S5Or P¢trr Bwerlty MBBS. ￿ FMedSEL
VktrCh•lf . Pffjlu￿ M•tth•w Collln. BM. uch. OPMI, MRCP, gRCPat
The Trustee5 regularly rDrfew ihe 5kiHs and comp051tlon of thelr body and conduct surcossion plannln8. Thev
rwuft new Trustees based on experlence. •mpathy. and knowled&e ol the ch•rtt% yèar, th* Tru5the Board
Introduced and O￿labOrat•d whh an elected Ad¥isary Panel.
As we mo¥• Into our new finanilal year TN$t*￿ will retire at ihe end of iheir term i)f nfflr.p k¥ith th• Charbiy
alwa￿ w• twlll take Ihls QPPOrtuntty to I￿th¥ our Gi>vemance structurn and assess the bènefits of utili5in8 any
opportuftftles Inay b• from adlysory boarfs allo•AnB 115 to more fumy support the Ext￿tI
DirKtor in fvnhcomlni projects and inliiatives and at the same tlme focus on Ouf Stftnnhs.
FundratslniRey￿at1t
The Cbartty ts re&ste￿d with the Fundra￿￿￿ RewJlator is in lull compliano with sts ￿quireMEnts. T*
Charfty adhere5 to the key prln¢lpJes and behaVi￿r5 in that the work of its fundrntslng will be l*gal, Open,
Hon*stand Respothl.
ftlskspanayrnent
The Tnjstees h•NY onsld*rEd the maJor rl%ks to which the charfty is exposed ènd revÉewed thctst ￿kS and
•5tabli5hed Swms and prncedU￿ to marnaBe those rts&&
The Trustees con5idervarlabilityof investn*nt retums.

HISTKI UK
TRUSTEE5' REPOVIT ia)NlliiuED)
FOR THE VEAR ENDED31 MARCH2025
O¥rth•n
The Charrty wishes to express ILS ¥rntilude to all Our ¥oluntetrts lor th￿r fifrndiatslrw artfvltfe4 ted￿1￿1 5￿J[[S,
and partidpatlon In vfrtual and phyycal eversts that ho¥e tsken place throu8hout c￿ntry in thb dNficuIt
VE4r.
Our thanks to our Co￿￿at* donots includlng those matth fvnding pr0￿MM￿S ￿thkh our
sup
er5
'th the. own fundraising ocU¥itieS.
Th
ees.
port
appwved by the 8oard of Trusteés.
MrA Kont
Trustee
nl& (half

HisnocYT051S UK
HISnO UK
srATEMvifoFTrU51EES' IIESP(X4518iun
The trustees n re5P0fi51bte for PrnPaTtsy the y￿Stee$, Aeport and the Ilnandal staternefvts kn •C￿nIanCe wlth
appfKable law and Unitrd ffftgdom A¢(ountiry standards {Uniied KJn8thm Genor41fy knopted A￿)untI
PTrctlcol.
The law applkable to thaiilies In England and Wales reouiles the trustees to prepar¢ financl81 #•tements for each
financial year whith 8l¥e a tNe and lalr ￿tW OF the state of afl•lr5 of the charlty •nd of ihe lTrwmln6 rtsourtes
aThd applkatlon of ￿SourCeS of the c￿rffy for th•t year.
In prEP•rf￿ th•se nTr•n¢lal Sta￿Menty thetnJsTeuare rEquI￿d to:
. 5elttt su5table•ctyinttry pDU<kns and iheD apply th•m ¢0nslslently*
- observe ihe meth¢)ds •Thl principles in the Chariites SOAP,.
. makeludsements afid estlmaths thatare reasoTrable •nd prudent;
- stste whether applOc•ble accoLtntsn8 stsodartls have b•en follow•d, sublecl to any m4t•riaf d•pJrtur•s dkclosed
•nd eTpknlntd In the ftFwidal itsthments; •nd
- We￿re the finarKa•l 5tstements on the 8oln8 concern b•sts Unle￿ It Is happtoprFatt lo prnjume th•t thechartty
wlll cantinue In operntl+)n.
The trustees are responsible for keepln8 sufficknt accountin# record5 thai disclose with ￿aSonable 4ccuraLy at
any tsme ihe flnJn(ial poSsi￿)n of tho olar#y af5d enable them tr en5Ult thit the financial slztements comply wr¢h
the Chorilles Art 201J. the Ch?rfiy {Attoutts and Aeportsl Ro8ulatlons 2008 and the prDvlsion5 af the trnst deed.
They are also resporbslble for 5af*Ruardini the assets of the charity anrl fr>r taki￿ reasonable steps lor the
prevention and det•ctk>n ol fraud and other Irr*Kularilles.

HSTiocYrosis vx
Hisllo UK
IPIDEPENDENT EXAMINER'S REPORT
ID THE TRU5TEE5 QF H15nocYT0515 UK
I lE￿)rt to thè tiustees on w ex3minatlor* of the Ilnanclal 5tsfrments of HIstloL￿ UK Ithe ch•iityl for th?
year endtd 31 March 2025.
Re5ponslbllltles and tsasls of ￿ptsrt
As the tr￿tee5 of iht Ch￿lty you are rnsponjlble lor thE prnparniion of the finandal stst•m•Thts In
accordance with the rèqulfyments olthe Charfties Act 2011 (the 2011 Att).
I feport Sn respert of my examlnation of the chaiitV5 fnoncial ststements carrfed under sertlon 145 01
thè 2011 ACL In otrt nry exarninatltsn I hawe follo*Ed all ihe appliobl& ￿le£ll0n% Khen ty the
Commi$5ion under sedion 14515llbl of the 2011 ACL
IndepeTrdtnt 5tstrm*nt
Your anentttsn Is drnwn to the Fart that the ¢hartty has prnpantd flnaftd•l 5ta*ments In accardance *rfth
Aco)untinK and Reportin8 by CharitFes preparing iheir actounts in gc£ordance with thi Flnanclal ftEportlry
S￿ndard appl•¢able in the UK and ftepubtic Df IreSafrd IFRS 1021 In preference to the A¢rnuntlry and
Ileportwbg ty Charitses: Ststtrnent of Recummended Pnctire Issued on l Apry 2005 which Is rnfvnwd kn In the
•xtsnt re8ulat10ns has now been withdrnwn.
l understsnd ihat th15 has been done In orOer for f￿ancial ststements lo provk*e a tr￿ and f•lr vlew In
auofdance wlth Genernlly Accepted Accounting Prnctke effectlve for rnportinl ptrfjods b¢8lnnln8 on or after
I lanuary 2015
I have omple￿￿ tny tyamlnatlon. l ￿f1fiMI that no mattws Iwe come to my 4ttenil¢n In connecllon wlth
the eurnination 81¥in8 me Guse to belle4Y thai In airy materfal rtspect:
accountlftB records W*PE not ktpt In ￿sp•ct ol the th•rlty as rEquir•d by se(tloll 130 01 the 2011 Pxt: or
the frnanc5al statsments do pot ￿￿ord wlth those rzwrds." or
the financial statEments do not cornply with the applicable requirements conornlng the form and
content of accounts set ts￿t In the Charities ¢AcC(￿nts and Reportsl ReBulations 2LXJ8 other than ary
requiTrmtnt th4l the accovnts 6t¥e a tnje and f•lr th whith Is not • matter fLmsld¢rnl as p•rt of •
Independent eyamln4110n.
I have no conterns and hawi come across no other mattefs in conne¢tion wlth itte examlnjtlon to whkh
/ttentiDn shoutd be drdwn In ih15 report In order to enable a proper understandlni of financlal
ststements to be Trached.
Christopher McKenna ACA
rcGmup
33 8ollon Boad South
Hrjlbeach
Spaldin8
Uncoln5hlre
PE12 7LR
2317125

Himocrfosis UK
Hisno ux
srATEMEKf OF FIPIANaALAcnvmES
IIICWDINGINCOME AMI EXPEPIDflliRE ACCOIINT
roR niE VE4REP￿EO3l A14A012Q25
fvnds
2014
20
Inojme ITUM:
Donations and lapclos
Investmen
123.185
5.363
111.963
Totsl Income
118.548
126.827
Ra15ini funds
Charitsble a¢tt¥Stteg
Other exP￿d[tU
i.lc
131,783
271
1281
138.011
li
133.ly
,292
Plrt •xp•ndliw• and mvmmqrt In funds
14.6061
112.4651
Aecofidll•tlon of fvn
Fund balanct5 •t l April 2024
403,712
416.177
Fund b•l*ncu•t31 Math XOIS
a99.106
4•3.712
The ststèrnent of fffwnclal actMtle5 Indudog all and 105ses recDonts•d In the year. Atl Incame #nd

HisnocYT051S UK
Hisllo UK
BAIANCE SHEÉF
ASAT31 hlARC112025
Amd •sMts
Tangible assets
387
R5
Cufventassets
Debtor5
Cash at bank and In b4nd
14
941
405383
403.027
404.008
406.324
cr￿it0￿. amounts lallrf due wtthln one
15,2891
13.4621
398,719
402,862
Totsl ass•ts less 04rMAt Ilablllths
399.106
403.712
N•¢ •55•ts
399.106
403,712
Th• I￿15 ulth* th•rlty
UfftreMri¢ted fvr
399.106
403,712
399.106
403,712
v￿re approved by the trustees on .n..O.ts--.W￿<
Mr A %Dnt
Trus*e
nnS5. Chalt

H15TIO UK
Pa￿Es 7D TFIE FINANaAL sfATEMEP47S
FOR THE YEAR EM>ED31 MAft012025
Ar£aunthypolld•
The flnandil StateM￿ts h•ve been prepared In accordance wlth the dwrlty's 8vvemlni document. th•
Charities Att 2011 and 'Accountiry and Ileportln8 by Charities: 51atement ol Recommended Practice
applkabfe to thariues prep•rino thitr acujunts in accothnce whlk the Financial Reponlry Standard
applicable In the UK a￿d Republic of Irel4nd IFf6 1021 leffeaive i January 20191". The charity Is a Publi
Benefit Entliy45 dellned by FRS 102.
The thartty lla% tak•n •d￿ntry of th• pro4ryslon$ IB the 50RP for tharltie$ applwni FRS IOZ Update Bulletin
I not to preparn a Statwnertlol Cash Flows.
The financial stst•rnents departed fTvm the Ch4rltles {Attounts and Reports) Re8ulaUons 2008 only tL¥
the exteftt to pn%ide a tn￿ and fair view. Thi5 departurn has involved loll¢y*Jing thE Ststement of
Recommended Pnctke lor chariiles apply5nq Fli8 102 rdthttr than ihe of the Statement of
Recommend￿1 PrnLllce whlth 15 referred to in the Regulations bui which has since been withdrnwn.
The flnèntlal 5tatRments arE prEpared in sterlln& wldch 15 lh¢ functi?￿1 curTen¢y of the tharlty. Mtjffierary
amounts in finanoal ststements aTr rourbded to tht ne•re#L
Th• flnandal stst*ments bo*n P￿pa￿d unthr the hl#orfc41 ￿5t comwitlor•, tmodifi¢d to Include the
revaluailon ol freehold pr¢portles and to include kn¥estment propertles ar￿ cel￿1n financlal Instruments at
fair ￿lUe1. The principal accoun¢in¥ pDlides adopted are set out belw.
L2 Gohw(anr•rn
At the tirne of approvln8 the flnandal statements, the trustees have ? w50nable ¢Ype¢tatlon that the
charlry ha5 adequate ￿OUrceS to conlSnue In operational ex15tence IDr the fU￿See•bIe fut￿￿. Thu5 lh•
tIUSlees contlnue to adopt the 8olng con£ern basis 01 aCCDuntln8 in preparlni the financlal stslements.
Ll Ch*rEtab￿ funds
UnresTf*EEd funos tsr ust * the dlsrtSon ￿ the trust•ts in Itrth•r•ncv of tholr chwltable
Rexfitted funds are svbjert to speclfic conditlons by donots or as to how thry may be used. The
puwes uses ol the ostrfaed fwxls arn s•t out In the ntstes ta the financlal stattments.
Endowment funds arE 5ubiert tt> Specif￿ conditions by donots that ihe capltal must be milntsined by the
1.4 Incom*
Income Is fKo8Tr15ed when Ihe tharltyls legally erbtltled to it aftèr ary performance cornlltlons beeft
met, theamoimts on be measured reli•bEy, and it is pmbable that IrKome will be received.
Cash donatlons are wnised on receipt. Other donatlons recognised once ihe chartty ha5 bee
notlfl•d of ihe donaiion. unlets perfDrniance conditions rYquivE defeTral of the amount. Income tax
overable in relaiion to doBation5 FEcehed und*r Gift Ard or deEds of covenant is fe¢o8nised at the t5me
gf the doftatlofi.

MLsfiocYTOSIS UK
Mlsno UK
PIOTES TQ ThE FINANaAL 5fAIEMW5 IcofiTINUEDI
FOR THE YEARÉNDED31 MAft012025
LeBaci85 ar• r•co8n15ed on receipt or oth?rwise If ihe charity h35 been nDJfied ofan Im￿ndIn1 dlstr6butlon,
the amouni Is known, and rpcelpt rs expeaed. 11 the amount 15 not known, the legacy Is trn•ted is a
contingent assei.
IS Expendlture
All expendI￿re ¢s reCo￿lsed once there is a Iwl or coTrArnrtlve obli8at5on to that expendltufe, tt is
probable settlefftent Is foqulwd and the amiwnt can bè measurEd reliabl¥. All costs •re allDc4ted to the
applicable expenditure heading ihat a88re8at• Stmil•r costs to th4i ¢ats80ry, Wfvere costs ¢8nnot be directly
attributed to particular headlngs tbey have been allocated on a ba515 consSstoTrt with the use of ￿50VICeS.
with ren1￿1 stsfl ¢osts alkicated on the bas15 of tlme Spent, and depre£iatltyi Charg￿ allocated on the
portlon of asset'.4 use. Other support ¢¥ysts ar• •llocat•d based on the sP￿4d of staff CLUts.
These aro costs IncuryeLI In attractln8 ¥olunury Income. tlT• mana8ement of In¥¥trnents and those Incurred
In iradinqaetl¥rtles thai r4ise funds.
Charitable txpendltufe c4>mprls•s those rosrs Incurr￿ by the tharlty Fn the delhery of ￿ lctlvitres Jnd
services lor its benefKEaries. tt Includes ljoth c05ts that can be alloeated directly ¢0 suth arti¥ities and th￿e
Cl)Sts of an IndlTErt nalu¢e fiecessary io support them.
1.6 Tanwble IIM•d
Taw'ble fLwI assets arE inttlally measured it cost and subsequ•nUy MeasU￿d at cost or r4luatlon, rtet ol
deprEclatlon aftd ary impairrnent loss•s.
DeP￿C[atIOn is wnlsed $0 as to wrtte off the cost ar raluatlon ol ass*ts less thelr resldual ¥il•Je5 ovor
Ihelr usefvl Ir¥es the folk>wln8 bases:
OffKe equipment
33% f*du¢in8 balantè
The Din or loss arfslni on th• dtsposal of an a￿t 15 dltsfftilfted as the dlfference between the SBle
pmceeds and the carrying wdlve of the 355et, and is rewinised in thestatement oifinandal activitles.
1.7 Impalrnient ol IINed a55•ts
At each fEPDrtlThg end date. the charity revfews the carryin8 amounts ol Its tsn8lble assets kn ￿erni7￿8
whether there is any Indi¢atlan that those a$5ets svffEfEd an Impairment lo￿ If any suth Indkation
exis18 the reCoVera￿e amount ol the 3sSQt is estimated in oidw to determine the extent of the Impabrment
1055 lif any).
1.8 Cash and ush equlv•l•ftts
Cash and osh e4vlYJlents in¢lude cath in hand. deposils held at oll with banks, oihei short-term Ilquld
Investrnerrts with on￿n￿l rnatuffties of ihrte months of le$5, and bank o¥efflTrft5. aank <w*nlrafts •re
5bown wlthln borrowlry in Cufrent liabllttlo5.
li

HisnocYr0515 UK
H15llo UK
FOR ThE YE4R ￿DED31 MARCH21125
Ar￿UntI￿ polkl
(Coniiv4w•d)
The tharity ha5 dKted to ¥ply the pro¥islons OF SertloA 11 '8a5k Finan¢i•l In5tfyments' 4nd SectlJTr 12
lthlr FIMKhl Instrnments IS$￿ ol FRS 102 to all of tts financlal instruments.
Flftanflal InstNments ￿[o￿lSEd In the charftys balance sheer wh*n the charfty becomes party to the
controttual pruvlslorts of th•1fistrument.
Flnoncial assets and IlabHltles •re offseL wlth th• nrt amounts pres•nted in the firnandal Statements, wheft
there is a le8ally enftjrC4ab￿ riiht to set off the wl%ed amounts and there Is an Intenkn ty settk on a
net basEs or to ￿111$e theasset and settle thtt liabM*islmultsneously.
8a51c financlal *ss•ts, which Include Jnd cash and bank balan¢•s. •re inltlally measured at
trnnsa¢tlor+ prlce includin8 trar￿alon Costs and are subsequently cardtd at amorttsed cox USinK the
If*cti¥• 5thr•Jt method unless the arorwment ￿n$t￿lUt*S a fi￿n￿nI tran5a£tton, where the trnrtsxtlon
k rnea5urtd at the pre5eni *Alue of the futurv recelpts discountod at a mèth r4te of Ini¢rest ￿nandal
assets Cla￿rIed •s rece￿ble wlthin one ￿•r not omorihed.
8aslrfvofidal&Yobllldes
Bask flnanual liabllltl•s, IncSudln8 ¢redllots •nd bank loan5 are Initlally reco8ni5ed at tr4n5aclloft prk• unless
the •rrdn8ement eonstltutes a finanon% tr3n50Ction, where the debt Instrument IS measured at the prESent
¥7lue of the fvtUfE p•ymentsd6swunied ot a rnark4t rdte of Intern5L Flnancial Ilabllltles dassbfied 47$ payable
whhlnone yeai are not arnort&ed.
Deljt Insrrnm•nts are sUb5Qqut￿1¥ ¢4rrled at amortljed ¢usL u51ng fbe effecti¥Y illter*st rate mthhod.
Tr•d• u•ditors are obli6•Uvns to pay for loods or se*¥lces ihat been acqulred in the Qrdlnary course of
operatlons from suppllern Arntsy)lts payable arE classlfied a5 cufTent Ilabllltles 11 paymeftt Is due withln one
vear or le$5. If nDt. they are pwmed as non￿rrent IlablNtbE& Twade cr*dItO￿ •we FE(rgntsed initiaifv at
trnnsartknn prke 4ftd 5ubsequen¢ty mea5wed at amortlsed cost Use￿ the effprtfve interpst mEthod.
Flnancial liabllll*s a￿ deretO8ni5ed when the charftyes contrac￿11 obli8aiions explrE or are dlxhaiged or
17ncelle
LIO EmPlo¥eeb￿¢fftS
The cost of ary unused holldoy entltloment Is ￿(DInIsed In the perlod In whlch the empknyee's 5er¥kes are
feceNed.
Terrn•nation benefft$ recagftsed Imme(fi•tety Js an ￿pense when the tharlty 15 dem0rttt1a￿V
cornTr4tkd to ten￿￿￿e the eMplo￿￿ent o14n ernplayee or to pro¥ide ternb5natkn benefft%.
12-

HisnocYr0515 UK
Hwlo UK
NOTES TOThE FIP4At4aALsfAYEMEl4f5 (COtinNUED)
RJR THE YEAR ENDED 31 MAR012025
Ctltlul a¢w￿rtI￿ e5ttm*s •dh*¢ments
In the applkatkbn of the charfvs a<countln8 pollcie5. the trustees are r¢qulr•d to make Judi&m￿ls,
e*imares and aSSLbmptlon5 aboui the tanying ￿n0￿￿t ol assets 4nd liabilities that are not feadily apparent
from other sources. The e#lm*es and assoclated assump1k￿5 a￿ based on hlstorfal eyperlence and cther
factors ihar aTr conside￿￿ ￿ be ￿le¥an& Pthal ￿SuIts MaydI￿rI￿rn these estimate>
The ostlrna1￿ and underfyln8 8swmptlons •¥E revlewed on an oniolry basls. ft•¥is1tyts to •rtountlnu
estlm•tes are iecggnised In the pethd In whlch the *stTrmate Is revtsed whae Ihe misloD aifects only that
period. or in the perfod of the rEv151on and futur• perlods where lht r•¥isl(m affEcts boih curr•nt and lurure
pertods
Income frnm don*S(ths and le••d*s
20
2024
Dffiations #nd ilfts
123,185
121.963
Donatltsns
Giftaid tsx redaimed
121926
259
120,569
1.394
123,ts5
121.963
Incoffle frnm lrnAstm•srts
nd5
Intefest recehAble
s,a63
13

HJSTIoCYTO￿ UK
Hisno UK
NOYES TO THE HNANaALsfATEME1115 ICONllNUEOI
FOR INE Y£4R ENDED31 AIAR012025
uTrYNtrkl￿ Uftrt#rfct•d
fvr
1025
20247
Generdl fundrdlsin8and event expens
I,IOD
Ll81
i.ioo
1.281
Ch•rftsbl• •thhl
Ch•fllatsle tswftabl•
ewdlttsro &PendI￿re
1025
2024
Staff costs
D•prnci¥t50ft
Outreath costs
Trn¥ellln8
Insurance
T•l•phone
Computer ewnses
Pdrtllbl. P05tsRe. 5t0tl0nery￿d adverttsSn8
Ac£ountsnry. bookkee&¥Èn4 and payrall f
Bank charyes
Iniefe5t payable
58,986
191
8.878
4,056
1,168
lJ34
871
2,142
S8.986
419
11,937
4.289
1.170
4,077
2,218
3,103
11
4Jiiia
ia8q
143
81.902
87.986
Grant tsndlnl af 4ttS¥lties Isee note 71
49*81
SO.025
131,783
138.011
14

N￿OcY[0￿s
HISTIO UK
NOTE5 TQ ThE HNANaAL sfAIEMENTS IcoiinNUED)
SOR THE V£4RENOED31 AIARCH2025
Charftsble
*xpendlturn E¥pwditUfe
2025
2024
Resèarch co*S
49.881
50.0
49.881
50.025
Net lunds
2025
1024
The net movement in funds15 5tsted after chargiTh8lluedldngl:
DepredatiDn of owrbed tsn8ible fkyed issets
L05$ on dIspo￿l of rdrylble fixed assets
191
271
419
9 Tru5th•S
None DI thÈ trustees lor any porwns connected whth them) re¢•W arry reffjuMAt5on orbtr¢fits lrnm lh*
chafity durfn8 the year.
10 Emplry
The avernge monthly number olempl¢)¥oes duriwdthoyear was.
1024
Numlb•r I￿rnb•1
Employm•rtLtsts
W•8e5 and ¥l¥ies
58.986
58.986
Thefèwere nD employ*eg whose annua5 r•munÈrntlon was more than £60,000.
15-

HisnocYTOSIS UK
Hlsno um
P40TES TO ThE RNANIJALSYA7EMEP¥W5 fCONllNuEDI
OR TIIE YEARE14DED31 MA&YOI2025
f¥nds
2024
20Z5
Net knsson dFsposal Df t•rylble fix•pJ 4$5*ts
271
The tharfty ts &¥empt lrnm laxallon on Its acti¥ltles because all Its income Is applled for charlkble purp05eS
T*￿￿* illed
At l Aprll 2024
DISPO￿15
5,490
35681
At 31 Marth 202$
1.92Z
D•prnd•tlgn 4nd Impalrmont
At l April 2024
Depreclatlon charyed In the ye4r
EllmSnated In Trspett of di5posa15
4.640
191
13.2961
At31 Ma￿h 2025
1.535
C•rrylw •mDunt
At 31 Ma￿h 2025
387
At31 Marth2024
850
14 Dthors
¥lmounts fvlllncd￿e wlthln ofte y•ar:
2024
Prnpaymfftits andaccnjed irwme
981
941

Hsno ux
NOTESTO THE RNAt4aAL sfATEMETh ICONnNUEDI
KIR ThE VEAR ENIW) 31 MAR0120
IS Crndt0￿. aM￿¢rts1￿UTAzdUI wlthln oney•ar
hw taN*ivn S[￿131 security
Accruals and defErTed In¢ome
1655
2.634
iJS0
1512
5,289
3.462
IG ul net issets between funds
fim
At 31 Math 2D25".
Tangible assets
Cufferf iss•tsllll•bilrtles1
387
39B.719
399.106
UnTrth¢t•d
fvnd%
At 31 Ma￿h 2024:
ng4ble assrf5
402,861
40J,712
17 Rdathd yrt¥ tr•ns•EUo
The￿ We￿ no dlsck¥sabfe related party transactions duiing the yeaT12024. nor)el.
17

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