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2021-09-30-accounts

Trustees' Annual Report for the period

Period start date Period end date 01 10 2020 30 09 2021 From To

Section A Reference and administration details

Charity name

INVEST in ME Research

Other names charity is known by IiMER InMER IiME RESIME Invest in ME

Registered charity number (if any) 11153730

Charity's principal address


PO Box 561
Eastleigh
Hampshire
Postcode SO50 0GQ

Names of the charity trustees who manage the charity

1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
Trustee name Office (if any) Dates acted if not for whole
year
Name of person (or body) entitled
to appoint trustee(if any)
Kathleen McCall Chairman
Richard Simpson Trustee
Joyce Wood Trustee

Names of the trustees for the charity, if any, (for example, any custodian trustees)

Name Dates acted if not for whole year

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Names and addresses of advisers (Optional information)

Names and addresses of advisers (Optional information) Names and addresses of advisers (Optional information) Names and addresses of advisers (Optional information)
Type of adviser
Name
Address
Name of chief executive or names of senior staff members (Optional information)

Section B Structure, governance and management

Description of the charity’s trusts

CIO Foundation Model Type of governing document (eg. trust deed, constitution) CHARITABLE INCORPORATED ORGANISATION How the charity is constituted (eg. trust, association, company) Appointed by Existing Trustees Trustee selection methods (eg. appointed by, elected by)

Additional governance issues (Optional information)

Invest in ME Research (IiMER) works to build relationships nationally and You may choose to include internationally with other organisations who promote similar aims. additional information, where relevant, about:  policies and procedures adopted for the induction and IiMER has continued to chair the European ME Alliance, a collaboration of national patient organisations and charities across Europe. training of trustees;  the charity’s organisational The charity also has cultivated links to many organisations, researchers, structure and any wider clinicians and healthcare staff and has initiated and supported European network with which the charity groups of researchers and clinicians who work together in research and works; clinical areas.  relationship with any related Our objectives are to facilitate high-quality biomedical research into ME parties; with international collaboration.  trustees’ consideration of major risks and the system and procedures to manage them.

Section C Objectives and activities

To promote and protect the well-being of sufferers of ME. To advance the education of the public in relation to ME. To promote research into causes and treatment of ME. Summary of the objects of the charity set out in its governing document

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The main activities are– Finding, facilitating and funding of biomedical research into ME. Continuing development of the Centre of Excellence for ME model that the charity has proposed and championed since 2011. Initiation of awareness and fund-raising activities regarding ME. Organisation of annual public International ME Conferences that attract doctors, scientists, researchers, patients and carers from around the world. Organisation of international research colloquiums to encourage new collaborative and cooperative possibilities for research into ME. Creation and development of network of young researchers for ME. Summary of the main activities undertaken for the Foundation and support of a collaborative European ME Research Group public benefit in relation to network for researchers to come together. these objects (include within this section the statutory Foundation and support of a collaborative European ME Clinicians declaration that trustees have Council network for European clinicians to come together to build had regard to the guidance knowledge and expertise around ME. issued by the Charity Commission on public Production of educational material (videos, booklets, journals and benefit) guidelines) related to ME. Maintenance of web sites for the charity, and European ME organisations containing educational information regarding ME and our initiatives and conferences Creation and administering of webinars to enhance education of the public regarding ME. Advocacy work to help patients in need.

Distribution of regular newsletters to patient groups, patients, healthcare staff, media, politicians and general public regarding ME. Chairing the European ME Alliance and participating in European collaborative projects regarding awareness of ME.

Additional details of objectives and activities (Optional information)

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The trustees and volunteers perform all of the charity’s work for free.

The charity does not have any salaried staff.

The charity endeavours to provide services, products and information for free or as near to cost price as possible, to avoid ME patients having to bear additional burdens around costs.

You may choose to include further statements, where relevant, about:

The charity has a Biomedical Research Fund that allows grants for research projects to be made in order to continue developing the strategy of biomedical research into Myalgic Encephalomyelitis.

The charity has a peer review process for examining applications for grants.

The charity attempts to initiate more biomedical research into Myalgic Encephalomyelitis with an emphasis on international collaboration.

The charity has published our policy on grant making on our web site.

We are continuing to support our proposal to develop a UK/European Centre of Excellence for ME that will include examinations and research facility into ME and would perform biomedical research into the disease and allow proper examinations and diagnosis for ME patients.

We have initiated several major research studies for ME that take place at major UK institutes.

Section D Achievements and performance

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Section D Achievements andperformance
Summary of the main
achievements of the charity
during the year
Invest in ME Research is a comparatively small charity.
Yet the charity continues to change the perception and
awareness of ME in scientific, media and public circles
through innovation and dedication.
No salaries have ever been paid in IiMER, as all work is
voluntary. We continue to see no need to employ an
expensive CEO as we have dedicated and committed
volunteers who bring the right skills, knowledge,
experience and, most importantly, passion to what we
need to do. In this way we maximise the funding that we
are able to direct toward biomedical research into ME and
events to facilitate education and collaboration in
research.
The charity continued to benefit from a loyal group of
supporters who have joined with us to progress biomedical
research into ME.
The charity continues to campaign for and facilitate more
rapid research and treatment development in order to
provide a better future for people suffering from myalgic
encephalomyelitis and their carers and families.
The charity continued to receive wonderful support from
the Hendrie Foundation with regard to our development of
a Centre of Excellence for ME proposal and related
research.
The charity again chaired the European ME Alliance
(EMEA). Invest in ME Research is one of the founding
members of EMEA, an important grouping of national ME
organisations from seventeen European countries that are
working together to raise awareness and effect change
across Europe. The charity has made enormous efforts to
raise the profile of EMEA and is looking forward to new
initiatives that will help all people with ME and their
families.
As chair of EMEA IiMER organised the first EMEA
Roundtable webinar – ME/CFS in Europe, which had
Tedros Adhanom Ghebreyesus from the World Health
Organisation opening the event.
The idea was to form a Roundtable of European
Stakeholders and Policymakers.
The charity also organised the videos from the event and
these are available on the EMEA website with all
presentations from the event.
The charity joined our EMEA colleagues in organisingapan

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Section D Achievements and erformance p

European survey if patients - the first of its kind comparing the situation and experiences of ME-patients across European countries. The charity continues to do a great deal to progress biomedical research into ME and raise awareness of the disease. Despite relatively few resources the charity manages to accomplish a great deal. The charity has now funded five PhD studentships to perform research. One of these will be in association with collaborative work being carried out between the UK and Sweden via collaboration with University of Uppsala and also in Norway with the collaboration in Trondheim. The charity has also been able to fund fully the only clinical trial for ME in the UK – and one of only a few in the world for ME - a remarkable achievement for a small charity and its supporters. The charity’s web site, social media sites and free newsletters continued to provide a platform for academic and patient voices concerning science and facts by providing current information, educational articles and opportunities for comment. As well as the main website for the charity we also maintain the web sites for some of the European organisations with which the charity is involved. Invest in ME Research has continued to promote the development of biomedical research to be based at a research and examination facility in the Norwich Research Park in Norfolk – a UK/European Centre of Excellence for ME. We view this proposal as one of the best ways forward for securing proper research and treatments for people with ME in the UK and Europe. In this we have been supported by the visionary fundraising initiative – Let’s Do It For ME (LDIFME) – a patient-driven campaign to raise awareness and vital funds for the proposed Invest in ME Research UK centre of excellence for ME. LDIFME includes many supporters who have given their efforts to make change possible. The charity had announced the annual International ME

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Section D Achievements and erformance p

Conference Week in London for May/June 2021. However, despite the many months of planning and organising exciting and stimulating agendas and initiatives for these events, the charity had to cancel all of this due to the Covid-19 pandemic and its effects on life in all countries. Due to the restrictions and safety requirements all of the in-person conference week events in 2021 were cancelled. The charity did, however, host the BRMEC10 international biomedical research into ME Colloquium – as an online zoom meeting. In order to make a difference research which were now not able to be achieved due to face to face meetings the charity worked with the European ME Research Group (EMERG) to prepare a different type of agenda that brought forward hypotheses for different areas of ME research. This proved a great success and was well received by the international audience and a paper will be issued for publication in a major journal. The pandemic has severely affected the charity’s plans and many other related initiatives and projects have been affected. Fundraising was also affected by this situation as many fundraising events were not able to take place - although despite this some social media events were able to take place to raise funds and Invest in ME Research Supporters won a Movement for Good Award from Ecclesiastical The research being funded by the charity was also drastically affected with many research institutes being closed or reduced in function. The charity repeatedly requested that NICE remove the recommendation for Graded Exercise Treatment (GET) as well as Cognitive Behaviour Therapy (CBT) from its guidelines for ME as these are shown to be deleterious to the health of people with ME. The charity argued that new guidelines being delayed leaves the door open for patients to be mistreated. In December 2020 NICE partially acceded to the charity’s request by adding a comment to this effect. When NICE published their new guidelines the charity responded with extensive and constructive commentary and appraisal – both to the draft and to the final guidelines.

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Section D Achievements and erformance p

The charity conversed directly with the NICE CEO to ensure that patients’ rights and welfare continued to be foremost when publishing new guidelines for ME.

Ian Gibson

In April 2021 our advisor, and friend of the charity, Dr Ian Gibson sadly passed away and we commented on our web sites and social media on the effect that Dr Gibson has on representing patients’ rights and raising awareness of the disease and of the work of the charity.

Various fundraising activities took place with the support of a wonderful set of supporters.

The charity had entrants for the London Royal Parks Half Marathon.

Multiple online events and campaigns were held to raise funds for research and more awareness of ME and our supporters combined to promote the charity in several online competitions which were several times successful in winning awards.

All of the funds received go fully to funding or facilitating research into ME.

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Section E Financial review

Brief statement of the

charity’s policy on reserves

Our reserves are held to meet expected and unexpected bills and to cover running costs and printing/stationery costs. Our objective is to use as much of our resources for the facilitation and implementation of biomedical research into ME and to raise awareness of the disease.

Details of any funds materially in deficit

Further financial review details (Optional information)

You may choose to include additional information, where relevant about:

The charity trustees feel that the best way to make rapid changes in helping people with ME is to fund and facilitate high quality biomedical research into the disease, and that this is best accomplished by developing the Centre of Excellence for ME in Norwich Research Park using the knowledge, experience, facilities and capabilities of the unique talent that exists there. This could be a UK/European hub for research.

To this end the charity has devoted most of its research funding toward this goal and to support the establishment of a European ME research network that can collaborate and share knowledge.

it is important to try to make the conferences and the educational material accessible to patients and their families, many of whom are unable to work due to the effects of this devastating neurological disease and due to no proper research strategy existing to create treatments.

The research colloquiums are also made available to invited researchers for free or at a much reduced cost in order to encourage research and international collaboration.

The charity continues to feel that better education of healthcare staff is the key to improving conditions for people with ME and their families. IiMER aims to provide all our work for free or at cost price.

We are an independent charity whose focus is on better education, better awareness and a strategy of high-quality biomedical research into myalgic encephalomyelitis.

We hope to continue to find, fund and facilitate research and provide a means for patient groups to raise more awareness of this disease – ME – and so enable a rapid resolution to be created by provision of treatments and cures from high-quality science.

Section F Other optional information

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Section G Declaration

The trustees declare that they have approved the trustees’ report above.

Signed on behalf of the charity’s trustees

Signature(s)
Full name(s)
Position (eg Secretary, Chair,
etc)
Date
Kathleen McCall Richard Simpson


Chair
Trustee
16thJune 2022
15thJune 2022
16thJune 2022

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Charity Name No (if any) INVEST in ME RESEARCH 1153730 Receipts and payments accounts CC16a For the period Period start date Period end date To from 01-Oct-20 30-Sep-21

Section A Receipts and payments Section A Receipts and payments
A1 Receipts Unrestricted
funds
to the nearest £
161,716
-
-
224
50
-
-
-

161,990
-
-
-
161,990
-
149
437
2,986
-
204,601
356
-
-
208,529
-
-
-
208,529
- 46,539
-
172,754
126,215
Restricted
funds
to the nearest £
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Endowment
funds
to the nearest £
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Total funds
to the nearest £
161,716
-
-
224
50
-
-
-
161,990
-
-
-
161,990
-
149
437
2,986
-
204,601
356
-
-
208,529
-
-
-
208,529
- 46,539
Last year
to the nearest £
General Donation,Legacies and Grants 161,716 52,672
Conferences and meetings - 7,443
Printed material (guidelines, booklets,
brochures, cards, journals etc)
- 242
Tax refund / Gift Aid 224 650
Fund-raisingCharityActivities 50 -
Bank a/c Interest - 19
- -
-
-
~~Sub total~~~~(Gross income for~~
AR)

161,990
61,026
A2 Asset and investment sales,
(see table).
-
- -
Sub total - -
Total receipts
A3 Payments
61,026

Meetings and conferences
- 13,448
Printingof Brochures,Books & Guidelines 149 -
Postage,Packaging,Stationery 437 95
Governance,Web Services,Advertising 2,986 193
FundraisingProducts/Equipment - 46
Biomedical Research 204,601 217,797
Bank Charges 356 376
- -
- -
**Sub total ** 208,529 231,956
A4 Asset and investment
purchases, (see table)
-
-
**Sub total ** - -
Total payments
Net of receipts/(payments)
A5 Transfers between funds
A6 Cash funds last year end
Cash funds this year end
231,956
- 46,539 - - - 46,539 - 170,930
- - - - -
172,754 - - 172,754 -
126,215 - - 126,215 - 170,930

CCXX R1 accounts (SS)

03/07/2022

1

Section B Statement of assets and liabilities at the end of the period

Categories
Signed by one or two trustees on
behalf of all the trustees
B1 Cash funds
B2 Other monetary assets
B4 Assets retained for the
charity’s own use
B5 Liabilities
B3 Investment assets
Richard Simpson
Signature
K.McCall
Details
Details
Lloyds
Details
Details
Total cash funds
(agree balances with receipts and payments
account(s))
Details
Unrestricted
funds
Restricted
funds
to nearest £
to nearest £
126,215
-
-
-
-
-
126,215
-
OK
OK
Unrestricted
funds
Restricted
funds
to nearest £
to nearest £
-
-
-
-
-
-
-
-
-
-
-
-
Fund to which
asset belongs
Cost (optional)
-
-
-
-
-
Fund to which
asset belongs
Cost (optional)
-
-
-
-
-
-
-
-
-
Fund to which
liability relates
Amount due
(optional)
-
-
-
-
-
Print Name
Kathleen McCall
Richard Simpson
Endowment
funds
to nearest £
-
-
-
-
OK
Endowment
funds
to nearest £
-
-
-
-
-
-
Current value
(optional)
-
-
-
-
-
Current value
(optional)
-
-
-
-
-
-
-
-
-
When due
(optional)
Date of
approval
Kathleen McCall 15/06/2022
Richard Simpson Richard Simpson 13/06/2022

CCXX R2 accounts (SS)

03/07/2022

2

Independent examiner's report on the accounts

Section A Independent Examiner’s Report

Report to the trustees/ INVEST in ME RESEARCH members of

On accounts for the year 30th September 2021 Charity no 1153730 ended (if any) Set out on pages 1 and 2 (remember to include the page numbers of additional sheets)

I report to the trustees on my examination of the accounts of the above charity (“the Trust”) for the year ended 30/09/2020.

I report in respect of my examination of the Trust’s accounts carried out under section 145 of the 2011 Act and in carrying out my examination, I have followed the applicable Directions given by the Charity Commission under section 145(5)(b) of the Act.

Independent I have completed my examination. I confirm that no material matters have examiner's statement come to my attention (other than that disclosed below *) in connection with the examination which gives me cause to believe that in, any material respect:

I have no concerns and have come across no other matters in connection with the examination to which attention should be drawn in order to enable a proper understanding of the accounts to be reached.

Date: 2/7/2022 Signed: Name: Paul Booth Relevant professional qualification(s) or body (if any): Address: 30 Provene Gardens Waltham Chase S032 2LE

October 2019

IER

1

Section B Disclosure

Only complete if the examiner needs to highlight matters of concern (see CC32, Independent examination of charity accounts: directions and guidance for examiners).

Give here brief details of any items that the examiner wishes to disclose .

October 2019

IER

2