REGISTERED CHARITY NUMBER: 1152876 REGISTERED COMPANY NUMBER 08331746 THE GOLDEN HELIX FOUNDATION REPORT AND FINANCIAL STATEMENrs YEAR ENDED 31 DECEMBER 2 Pwl THE GOLDEN HELIX FOUNDATION REGISTERED CHARfTY NUMBER: 1152876 a) R¢gl•teMI Addre4K" Arnold Hill & Co LLP Floor, Capitsl Tower 91 WatsrkK) Ro*1 SEI 8RT b) Bo*rd of Thiste￿. Ms Christina Mitrowu]ou Arnold Hill & Co LLP e Fkn)r, Capital Tower 91 Wthr1￿ Road London SEI 8RT d) B￿￿eTh: 36 St Andrew Square EH2 2YB Page 2 THE GOLDEN HELIX FOUNDATION DIRECTOKS, AND TRUSTEES, REPORT YEAR ENDED 31 DECEMBER 2023 The Trustees. who are also directors of the company. present the fmancial statements of The Golthn Helix Foundation (kn Charity") for the year ended 31 t)ecember 2023. They hav¢ been prepared in accordance with the accounting policies set out in note I to the accounty in ompliance with the Charity'5 Articles of Association, the Companies Act 2006 and the Statement of Recommended Pra¢tice, "Accounting and Reporting by Charitie5" appli¢able to ¢harities preparing th¢ir accounts in a￿ordartCe with the Financial Reporting Stsndard applicabk in the UK and Republic of Ireland (FRS102) effective from January 2019. OBJÉCTIVES AND ACTIVITIES The obj￿tIveS of th¢ Charity are to advanc¢ cducation in th¢ area of 8enome and peT￿naliSed medicine ty promoting the development of research and the trnnsfer and ¢ommuni¢ation of knowledge from researchers and scientists in the wider scientific community through collaborative projects and conferences in the field of pharnwogenomics and p¢rsOnalis￿ mdicine. The Trustees have paid due regard to guidan¢e issued by the Charity commissi(￿ in deciding what activities the company SI￿ll1d Undert￿¢. ACHIEVEMENTS AND PERFOR￿cK The Trustees provided public benefit by providing ¢ducation and training to the general public in the area of g¢nome and personalised medicine. through the organisation of a bi-annual summ¢r ￿h0o1 whue S￿dents can learn from genomi¢ m¢di¢ine specialists. The Chwity generated a deficit during the y¢ar of £25.514 (2022: deficit of £96,657). The reserves held 41 thc year-end amounted to adeficitof £4,148 (2022: a surplus of £21,366) and held to meetthe Charity's objeetivcs. Th¢ Charity is supported bythe Trustees to ensure thAt it¢aD ￿ntInue as agoingo)ncern. Basedonthis support th¢ Charity can fulfil its obligations and th¢r¢ ar¢ no major risks to the Charity. GOVERNANCE AND MANAGEME The Tnths may appoint any person to be one of their number. Th¢ Trustee5 review the knowledge and experience of the Trustees and identify training ne¢ds on appointment. Suitabl¢ training will be provided if required. Page 3 THE GOLDEN HELIX FOUNDATION DIRECTORS, AND TRUSTEES. REPORT YEAR ENDED 31 DECEMBER 2023 STAT£MEhT OF TRUSTEES, RESPONSIBILITIES The law applicable to ¢harities in England & Wal¢s require5 the trustees to prepatE financial statements for each year whi¢h give a true and fair view of the Charity's financial activities durtn8the year and of its financial position at the end ofthe year. In pt¢paring financial stslem¢nts giving a true and fair view. the trustees should follow best prnctice and: S¢lect suitable accounting poli¢i¢s and then 4)ply them consistently: Make judgements and estimates that ar¢ reasonable and prudent" Stat¢ whether applicable accounting standards ond 5tatcm¢nts of recomm￿ Pr￿1.". kave t¢¢ followed. gubje£t to any dwtvrts disclosed and explained in the statement4 and Prepare the financial statements on the going concern basis unless it is inappropriatr to presume that the Charity will continue in (4)eration. The 1rnst¢¢s are r¢sponsibl¢ for kecping a￿OU￿ting ￿ordS whiGh di￿105¢ with reasonable accuracy the financial position of the Charity and which enable them to ascertain the financial w)sition of the Charity and which enable them to ensure th8t the financial statements comply with applicable law. r¢gul*ions and trust a￿d. They atr also responsible for safeguarding assets of the Charity and h¢nce for taking reasonable steps for the prevention and detection of fraud and other irre8ularitie& Th¢ t￿Ste¢S. who are also the directors for the pUn￿8e of company law. and who sffved during the y¢8r and up to th¢ dat¢ of the signatsire of the financial statements were: Ms Christina Mitrop)ulL Dr Georgios Patrin()s Dr Darrol Baker Ms AikateriDi Patrinou (appointed 2 January 2024) Thts report ha5 been pr¢pard in a¢wrdance with the Special provisions relating to Small companies within Part 15 of the Companies Act 2006. I¥I.,: IL Approved on behalf of the Board on .. G Patrinos Director l Trnstee Page 4 INDEPENDENf EXAMINER'S REPORT TO THE TRUSTEES OF THE GOLDEN HELIX FOUIYDATION YEAR ENDED 31 DECEMBER 2023 I report on the accounts of the Trust for th¢ year ended 31 D¢wnb¢r 2023 which are set out on pages 5 to 10. RLSPEcfivE RESPONSIBILITIES OFTRUSTELS AND EXAMIi¥ER As the Charity's tru5t¢¢s you are responsible for the preparntion of the aceounts. you consider that the audit requirements of s145 of the Charities Art 2011 (the 201 l Act) and Part 16 of the Compani¢s Acl 2006 do n apply and that an independ¢nt examination is needed. It is my responsibility to examine the accounts under se￿10￿ 145 of the 201 l Act and to st*, on the basis of pr(Kedures S￿Ctf￿ in the Genernl DIr￿tIOnS given by the Charity Commissioners under s145(5Xb) of the 2011 ACL whether particular matters have com¢ to my attention. BASIS OF INDEPENDEKf EXAMINER'S REPORT My &umination was carried out in a￿[dance with the GeD¢raJ Directions given by the Charity Commtssion. An examination includes a review of the accounting r￿ordS kept by the Charity and a CA)mparison of th¢ pxcowits presented with those records. It also includes considerntion of any unusual items or disclosures in the accounts, and the seeking of explanations from you Ls trusttts concernin8 any such matt¢rs. The prwedures undertaken do not provid¢ all the evidence that would b¢ required in an audit and. consequendy? no opinion is given as to whether the ￿coUnts present a't￿￿ md fair view. and the repK)rt is limited to those matters sct out in th¢ slatsment below. INDEPENDENT EXAMINERS, STATEMEi In connectton with my examination. no matter has com¢ to my attention: (l) which glves me rwonabk cause to believe thAL in any material respecL the rqUir￿cnts. to keep a￿Unting reeonls in accordance with 5130 ofthe 2011 kn; and to prepare accounts which accord with the accounting r¢cords and to comply with th¢ a¢o)unting reqUI￿nents of th¢ 2011 Act have not been met; or (2) to Whic￿ in my opinion, attention should t¢ drnvrn in ord¢r to enabk a proper understandtng of th¢ accounts to be reached. LJTh(kGL Arnohl ￿11 & Co LLP Chartered Accountants and Registered Auditors 6 Floor, Capital lower 91 Waterloo Road ndon SEI 8RT Page 5 THE GOLDEN HELIX FOUNDATION STATEMENT OF FINANCIAL ACTIVrnES FOR THE YEARENDED 31 DECEMBER 2023 Year End 31D YeAr Eod 31 Deeember 2023 Donations and legaci¢5 26.944 45.358 Totsl Income and endowments 2&944 EXPENDITURE ON Charitable ￿tIvItIeS (51458) (25.514) 142.015 (96,657) Net (expenditureyincune 2lJ66 118,023 21J66 Re￿UrCeS carried forward {4.148) All the Chajity's activiti4% ar¢ Gl&s%d a5 Conttnuing. The Charity had no rwis¢d sutplvs¢s or d¢fi¢its oth¢r than th¢ d¢f￿1t £25,514 for the year. The notes on pages 7 to 10 forni part of th¢s¢ finan¢ial knents. Page 6 THE GOU)EN HELIX FOUNDATION BALAI¥CE SHEET AS AT 31 DECEMBER 2023 2023 DebtOT5 Cash at Bank 26,588 39,024 54.059 65.6l2 54,059 148$: CURRE￿ LIABILITIES Creditors (69,760) (69.760) (32,693) (32,693) 21,366 21,366 NET CuRRENr ASSETS (4. l48) {4,148) ToTALAssETS LESS cURR￿r ABIUTILS Resource5 brought forward Net deficit for the year Resour￿5 caryied forward 21 J66 25.514 118.023 (96,657) 21J66 (4,148) For the financial year ended 31 December 2023 the company was •ttitled to exemption from oudit under section 477 Companies Act 2006. No member of the company has dwited a notice. pursuant to section 476? requiring an a￿lt of these finan¢ial ststemfflts und¢r the requirements ofthe Companies Act 2(*)6. The dire¢tor5 acknowledge their responsibilities kn e￿$￿TIng that the ¢ompany keeps a¢￿Unting records which comply with section 386 of the Act and for FryaTing financi￿ Stst￿￿ents which give a true and fair VI￿ of the state of affaits of the company Ls at the end of the futaTKial year and of its profit or for the finon¢i41 year in accordance with the requirements ofsections 394 and 395 and which otherwise compty with therequirements ofthe Companies Ad 2006 relating ¢0 a¢cowM4 so far as applicable to the company. Approved by the Board and authorised for issue on .. TRtNOS Directorl Tn C MtTROPOULOU Director l Tft￿e Company registe￿d number 08331746 The notes on pages 7 to 10 forni part of these finan¢ial $tar¢m¢nts. Pag¢ 7 THE GOLDEIY HELIX FOUNDATION NOTES TO THE FINANCIAL STATEMENTS YEAR ENDED 31 DECEMBER 2023 AccouNfiNG POLICIES ) BgJi8 of prep4rntiom The fuTrancial statements have IMI prepared in aC￿[danCe with th¢ Charity's governing docunwiL the Companies Act 2(K)6 and "Accounting and Rcporting by Chariti￿. Statement of RetA>mmended Practice applicable to charities pr¢paring their a¢￿U￿ts in ac¢ordance with the Financial Reporting Stsndard applicable in the UK and Republic of Ireland (FRS 102)- (as amended for accounting periods commencing from l January 20I9). The Golden Helix Foundation wnstitutes a public t*nefrt entity as defined ty FRS 102. Th¢ accounts have dep8rted from the Charities (Accounts and Reports) Regulations 2(K18 1)nly to the ¢xtent reqlbired to provide a true and fair view. This d9>￿th h#s involved following the Ststement of Reeotnm¢nded Practice for charities applying FRS 102 ratherthBn the version ofthe Statement of Recommetukd Practic¢ which is referr to in the Regulations but which has sinee been withdrawn. The fmancial sta*ments are prepared in st¢rlin& which is the fiinctional currency ofthe cornpany. Monetary amounts in these financial statements are rounded to the nearest L The financial statements have been prepared under the historical cost convention. The disclosure requirwnents of section IA of FRS 102 have been applied other than whthE additional di5¢10sure is required to show a tru¢ and fair view. b) IAcomAng Rtsource• All incoming resources are accounted for when the Charity has entitlementto the funds. receipt is probabl¢ and the amount Is m¢asurable. c) Golng ConeerD Th¢ Tnsstecs have reasonable cxpectation that the Charity h&s adequate resour￿S to continue in operational existence for the foTeseeabl¢ fi)ture. Thus they continue to ￿0p¢ the going concern basis in prep8ring the annual financial statements. d) ReJouree• expeDded and support coats Resources expended arc recognised in the period in which they are incurred. Resourc¢s expended include allrtbutable VAT which winot be recovered Pagc 8 THE GOLDEN HELIX FOUNDATION NOTES TO THE FINANCIAL STATEMENTS YEAR ENDED 31 DECEMBER 2023 e) Financial Auets Financial assets ar¢ recognized in the Charity's balance sh¢et when the Charity becom¢s party to the contrnctual provisions of instrument. B&%ic financial assets. which includ¢ trade and other receivables and cash and b¥nk bala￿¢￿ a￿ initially measured at transactions price including transaction Costs. Financial assets are d¢recognized only when the contractual rights to the cash flows from th¢ assets expire. or when it transfeTS the financial &95ets gnd substsntially all the risks and rewards of ownership to another ¢ntity. fj Financial LiAbllltl¢J Basic fllmncial liabilittcs are initially measured at transaction pric Financiat ligbilities d¢rcco8nized WIM, and only wh¢n, the Charity's obligations are discharge4 cancell¢d. or they expire. K) Taxation No provision has been tnad¢ for t￿tion as the Charity is a publi¢ tw¢fit ¢ntity whith is exempt from UK direct taxation on its charitabl¢ a¢tiviti¢s. DONATIONS AND LEGACIES 022 Grants and gifts 26,944 45,358 45.358 26.944 Page 9 THE GOLDEN HELtX FOUNDATION NOTES TO THE FINANCIAL STATEMENTS YEAR ENDED 31 DECEMBER 2023 3. EXPENDITWRE ON CHAWTABLE ACTlVtTIES Trnvelling Wag¢s and salaries Other TranSYS projed wsts Arcountancy ank ¢haTg¢s Entertainment 26,517 10,793 5l.442 4929S 2,926 240 1.657 270 4.079 7Jl5 7.079 Lagal and professional fees 15.831 15,924 142.015 51458 No tNstees received remunerntion for their work &s tnLStees. In th¢ prior ye•r* Chri5tiD8 Mitrop)ulou w&s r¢mun¢￿ed for her work on the Tr8nSYS proje¢L Th¢r¢ wfflr no ¢mployees in the year (2022.. one). 4. DEFTORS Arcn￿d income 26,588 26,588 202 Accru81s 2.5(K) 67260 2,627 Oth¢r creditors 69.760 Page 10 THE GOLDEN HELIX FOUNDATION NOTES TO THE FINANCIAL STATEMENTS YEAR ENDED 31 DECEMBER 2023 6. OPERATll¥G LEASE C0MMrTh￿S At the reporting date the Ch8rity had outstanding commitments for future minimum leas¢ payments under non-canc¢llable operating leases. totalling 65.7￿. 7. RELATED PARTYTRANSACTIONS Qeorgios Patrinos and Christina Mitropoulow directors and trustees of Ik. eknfy. p￿a knve , I￿0mmodatIOn 8nd subsistence expenses on behalf ofth¢ Charity totalling £49,401 during th¢ year (2022: £36.979). These expenses are subsequ¢ntly r¢imbursed by the Charity. As 31 December 2023, th¢ ¢harity owes MT Patrinos and Ms Mitropoulou £66,885 (2022: £30.066). 8. CoNrROL The Charity is controlled ty its Tru5te¢s.