Docusign En¥ÈlopÈ ID." OFODA91&236E4044-89EC-AE8D71046643
REGISTERED CHAIUTY NUMBER: 1152876
REGISTERED COMPANY NUMBER 08331746
THE GOLDEN HELIX FOUNDATION
REPORT AND FINANCIAL STATEMENTS
YEAR ENDED 31 DECEMBER 2022

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THE GOLDEN HELIX FOUNDATION
REGISTERED CHARITY NUMBER: 1152876
REFERENCE AND ADMINISTRATIVE DETAILS
a) Registered Address:
Arnold Hill & Co LLP
6, Floor. Capithl Tower
91 Waterloo Road
London
SEI 8RT
b) Board of Trustees:
Ms Christina Mitropoulou
Dr Darrol Baker
Dr Georgios Patrinos
c) Aceountants:
Arnold Hill & Co LLP
6, Floor, Capital Tower
91 Waterloo Road
London
SEI 8RT
d) Banker5:
Royal Bank of Scotland
36 St Andrew Square
Edinburgh
EH2 2YB

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THE GOLDEN HELIX FOUNDATION
DIRECTORS. AND TRUSTEES, REPORT
YEAR ENDED 31 DECEMBER 2022
The Trustees, who are also directors of ihe ¢ompany, present the financial stateinents of The Golden Helix
Foundation ("the Charity") for the year ended 31 December 2022.
They have been prepared in accordance with the a¢¢ounting policies set out in note I to the account4 in
compliance with the Charity's Arti¢l¢s of Association, th¢ Companies Act 2006 and the Statement of
Recommended Practice, "Accounting and Reporting by Charities" applicable to charities preparing their
accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ir¢land
(FRS102) effective from January 2019.
0￿ECriVEs AND AcfiviTIES
The objectives of the Charity are to advance edu¢ation in the area of genome and personalised medicine by
promoting the development of research and the transfer and communi¢alion of knowledge from researchers
and scientists in th¢ wider scientific cotnmunity through collal)orative projects and ￿nferenCeS in the field of
pharniacogenomics and personalised medicine.
The Trustees hav¢ paid due regard to guidance issued by the Charity Commission in deciding what activities
the company shovld undertake.
ACHIEVEMENfS AND PERFORK4NCE
The Trustees provided publi¢ benefit by providing education and training to the g¢n¢ral public in the area of
g¢nome and personalised medicine, throu8h the organisation of a bi-annual summer school where students can
learn from genomic medi¢ine specialists.
FINANCIAL REVIEW
The Charity generated a deficit during the year of £96,657 (2021.. surplus of £7,568). The reserves held at the
year-end amounted to £21,366 (2021.. £118,023) and are being used to meet the Charity's objectives. The
Charity's assets are adequate to fulfil its obligations and there are no major risks to the Charity.
GOVERNANCE AND MANAGEMENT
The Trustees may appoint any person to be one of their number. The Trustees review the knowledge and
experience of the Trustses and identify training needs on appointment. Suitable training will be provided if
required.

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THE GOLDEN HELIX FOUNDATION
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DIRECTORS, AND TRUSTEES, REPORT
YEAR ENDED 31 DECEMBER 2022
STATEMENT OF TRUSTEES, RESPONSIBILITIES
The law applicable to charities in England & Wales requires the trustees to prepare finan¢ial statements for
each year which give a true and fair view ofthe Charity's financial activities during the year and of its financial
position at the end of the year. In preparing financial statements giving a true and fair view, the trustees should
follow best practi¢¢ and..
Select suitable accounting poli¢ies and then apply them consistently.
Make judgetnents and estimates that are reasonable and prudent,.
State whether appIl￿b]e accounting standards and stalements of recommended practic¢ have been
followed. subject to any departures disclosed and explained in the financial statements. and
Prepare the financial statements on the going concern basis unless it is inappropriats to presume that the
Charity will continue in operation.
The trustees are responsible for keeping ￿cOUntIng records which disclose with reasonable accuracy the
financial position of the Charity and which enable them to asc¢rtain the financial position of the Charity and
which enable them to ensure ihat the financial statements comply with applicable law, regulations and trust
deed. They are also responsible for safeguarding assets of the Charity and hen¢¢ for taking reasonable steps
for the prevention and detection of fraud and other irregularities.
The following trustees have held position of trustee and director during the year..
Ms Christina Mitropoulou
Dr Georgios Patrinos
Dr Darrol Baker
This report has been prepared in accordance with the special provisions relating to small companies within
Part 15 of the Companies Act 2006.
Approved on behalf of the B(wd on .
G2
nos
Director / Trustee

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INDEPENDENT EXAMINERgS REPORT TO THE TRUSTEES OF
THE GOLDEN HELIX FOUNDATION
YEAR ENDED 31 DECEMBER 2022
I report on the accounts of the Tnjst for the year ended 31 December 2022 which are set out on pages 5 to 10.
RESPEcfivE RESPONSIBILITIES OF TRUSTEES AND EXAMINER
As the Charity's trustees you are responsibl¢ for th¢ preparation of the accounts- you consider that the audit
requirements of s145 of the Charities Act 2011 (the 2011 Act) and Part 16 of the Companies Act 2006 do not
apply and that an independent examination is needed. It is my responsibility to examine the accounts under
section 145 of the 2011 Act and to state, on the basis of procedures specified in the General Directions given
by the Charity Commissioners under s145{5)(b) of the 2011 Act, wlietheT particular matters have come to my
attention.
BASIS OF INDEPENDENT EXAMINER'S REPORT
My examination wa5 carrÉed out in accordance with the General Directions given by the Charity Commission.
An examination includes a review of the accounting records kept by the Charity and a comparison of the
accounts presented with those records. It also includes consideration of any unusual items or disclosures in
the accounts, and the seeking of explanations from you as trustees concerning any such matters. The
procedures undertaken do not provide all the evidence that would be required in an audit and, consequently,
no opinion is given as to whether the accounts present a 'tru¢ and fair view, and the report 15 limited to those
matters set out in the statement below.
INDEPENDE￿[ EXAMINERS, STATEMEwr
In wnnection with my examination. no matter has come to my attention:
(l) which gives me reasonable Cause to believe that, in any material resp¢cL the requirements..
to keep accounting records in accordance with s130 of the 201 l Act; and
to prepare accounts which accord with the accounting records and to comply with the
ac¢ounling requirements of the 2011 Act
have not bcen mct; or
(2) to which, in my opinion, attention should be drawn in order to ¢nable a prop¢r understanding of th¢
accounts to be reached.
Docu¥￿n￿d ty..
21003CA453438
Arnold Hill & Co LLP
Chartered Accountants and Registered ALtditors
6 Floor, Capital Tower
91 Waterloo Road
London SEI 8RT
28-sep-2023 1 1..33 PM BST
Date:..........................

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THE GOLDEN HELIX FOUNDATION
STATEMENT OF FINANCIAL ACTIVITIES
FOR THE YEAR ENDED 31 DECEMBER 2022
Notes
YeAr Ended
Year Ended
31 December
31 December
2022
2021
INCOME AND ENDOWMENTS FROM
Donations and lega¢ies
45,358
209,864
Total Income and endowments
45,358
209.864
EXPENDITURE ON
Charitable activities
142015
202 296
Net (expenditure)lincome
(96,657)
7,568
R¢sourc¢s brought forward
R¢sourc¢s Carried fonvard
118,023
110.455
21,366
118.023
All the Charity's activities are classed as ¢ontinuing.
The Charity had no recognised surpluses or defi¢its oih¢r than the deficit £96,657 for the year.
The notes on pages 7 to 10 forni part of these financial statements.

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THE GOLDEN HELIX FOUNDATION
BALANCE SHEET
AS AT 31 DECEMBER2022
2022
2021
Notes
CURRENT ASSETS
Debtors
Cash at Bank
127,634
26,737
54,059
54,059
154,371
LESS: CURRENT LIABILITIES
Creditors
(32,693)
(32,693)
(36,348)
(36,348)
NET CURRENT ASSETS
21,366
118023
TOTAL ASSETS LESS CURRENT
LIABILITIFS
21,366
118,023
REPRESETr￿ED BY
Resources brought forward
Net surplusJ(deficit) for the year
Resources ¢arried forward
118,023
110,455
21,366
118,023
For the financial year ended 31 December 2022 th¢ Company was entitled to exemption from audit under section
477 Companies Aet 2006. No member of the company has deposited a notice, pursuant to section 476, requiring an
audit of these financial statements ynder the requirements of the Companies Act 2006.
The directors acknowledge their responsibilities for ensuring that the company keeps accounting records which
comply with section 386 of the Act and for preparing financial statements which give a trne and fair view of the
state of affairs of the company as at the end of the financial year and of its profit or loss for the financial year in
a¢¢ordance with the requirements of sections 394 and 395 and which otherwise comply with the requirements ofthe
CoEnpanies Act 2006 relating to aceounts, go far as applicable to the company.
These financial statements have been prepared IT) a￿OrdanCe with the provisions applicable to eompanies subject to
the small companies regime within Part 15 of the Companies Act 2006.
. 1£¢4.Lknwr 2<)23
Approv¢d by the Board and authorised for issue on ..*.
G PATRINOS
Dire¢tor / Trustee
C MJTROPOULOU
Director / Trustee
Company registered number 08331746
The notes on pages 7 to 10 forni part of these financial statements.

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THE GOLDEN HELIX FOUNDATION
NOTES TO THE FINANCIAL STATEMENTS
YEAR ENDED 31 DECEMBER 2022
ACCOUNTINC POLICIES
A} Basis of preparations
The financial stateJnents have been prepared in ac¢ordance with the Charity's governing
document, the Companies Act 2006 and "Accounting and Reporting by Charitie5'.
Statement of Recommended Practice applicable to charities preparing their accounts in
accordance with the Financial Reporting Standard applicable in the UK and Republic of
Ir¢land (FRS 102}" (as amended for accounting periods comm¢n¢ing from l January
2019). The Golden Helix Foundation ¢onstitul¢s a public benefit entity as defined by
FRS 102.
The accounts have departed from the Charities (Accounts and Reports) Regulations
2008 only to the extent required to provide a true and fair view. This departure has
involved following the Statement of Recommended Practice for chariti¢s applying FRS
102 rather than the version of the Statement of Recommended Practice which is r¢f¢rred
to in the Regulations but which has since been withdrawn.
The financial statements are prepared in sterling, which is the functional currency of the
¢ompany. Monetary amounts in these financial statements are rounded to the iiearest £.
The financial statements have been prepared under the historical cost convention. The
disclosure requirements of section IA of FRS 102 have b¢en applied other than where
additional disclosure is required to show a true and fair view.
b) Ineoming Resource$
All incoming trsources accounted for when the Charity has entitlement to the funds,
receipt is probable and the amount is measurable.
e) Going Concern
The Trustees have reasonable expectation that the Charity has adequate resources to
continue in operational existence for the forese¢able future. Thus they continue to adopt
the going concern basis in preparing the annual financial ststements.
d) Resour¢¢s expended and support costs
Resources expended are recognised in the period in which they are incurred. Resources
expended include attributable VAT which Cannot be recovered

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THE GOLDEN HELIX FOUNDATION
NOTES TO THE FINANCIAL STATEMENTS
YEAR ENDED 31 DECEMBER 2022
e) Financial Assets
Fin&ncial assets are re¢ogniz¢d in the Charity's balance sheet when the Charity becomes
party to the contractual provisions of instrutnent.
Basi¢ financial assets, which include trade and other receivables and cash and bank
balances, are initially measured at transactions price including transaction costs.
Financial assets are derecognized only when the contractual rights to the cash flows
from the assets expire, or when il transfers the financial assets and substantially all the
risks and rewards of ownership to another entity.
Financial Liabilities
Basic financial liabilities are initially measured at transaction price.
Financial liabilities derecognized when, and only when, the Charity's obligations
are discharges, e8ncell¢d. or they expire.
Taxation
No provision has been made for taxation as the Charity is a public benefit entity which
is exempt from UK direct tsxation on its charitable activities.
DONATIONS AND LEGACIES
2022
2021
Grants and gifts
209.864
209 864

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THE GOLDEN HELIX FOUNDATION
NOTES TO THE FINANCIAL STATEMENTS
YEAR EIYDED 31 DECEMBER 2022
3. EXPENDITURE ON CHARITABLE AcfiviTIES
2022
2021
Travelling
Wages and salaries
Other UPGX project fees
TranSYS project costs
Ac¢ountancy
Bank charges
Entertainm¢nt
10,793
51,442
7,459
48,996
126,812
49,295
2,926
240
9.556
204
4.079
Rent
7.315
Legal and professional fees
Sundry expenses
4.975
4,294
142015
202 296
No trustees r¢c¢ived remuneration for their work as trustees. Christina Mitropoulou is
remunerated for her work on the TrdnSYS project.
There was one employee in the year (2021.. one).
4. DEBTORS
2022
202
Accrued income
127 634
127,634
5. CREDTfoRS
2022
2021
Accruals
2,627
8,101
Other creditors
30,066
28,247

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THE GOLDEN HELIX FoufqDATION
NOTES TO THE FINANCIAL STATEMENTS
YEAR ENDED 31 DECEMBER 2022
6. OPERATING LEASE COMMITMEIYTS
At the reporting date the Charity had outstanding commitments for future minimum lease
payments. under non-cancellable operating leases, totalling É12,540.
7. RELATED PARTY TRANSAcfioNS
Georgios Patrinos and Christina Mitropoulou, directors and trustees of the Charity, paid travel,
accommodation and subsistence expenses on behalf of the Charity tolalling £36,979 during the year
(2021: £18,598). These expenses are subsequently reimbursed by the Charity. As at 31 December
2022. the charity owes Mr Patrinos and Ms Mitropoulou £30.066 (2021: £28,247).
8. CONTROL
The Charity is controlled by its Trustees.