REGISYEREOCOMPANY NUMBER: 08061944IEnBland and Waiesl
REGISTEReD CHARrrY NUMBER.. 1149170
THE
FJR
THE wrrERFLY AvM_C￿Rr[y UM
12 Gathway
N112UT

THE BurrERFLY AVM CHARITY LIMITED
CONTENTS OF THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31 MAY 2025
Pag
Report ofthe Trustaes
Independent Examinerfs Report
ststement of Financial Activities
Balance Sheet
Not•s to the Financial Statements
9 to 14

THE BU￿ERFLy Aini_G.wrTY
￿E￿p TME TRiisfEes
A THE YEAR ENP.ED 31 MAY2025
f￿a￿oI $lalem*ts of tknty year eTr1eO 31 2025. Im￿eeS haye •W the of
a￿darKe the Rer*Nlry Stsrthrtt appf¢•ble n I1* Rerth of I￿￿ThJ IFRS 1021 leffetsNe 1
J3nuary20191.
O&JECTIVES ANDACTJVMES
ObJ•etfv•$ and akns
IAllk151. The a&)p￿] ol L*"eLts are w false Èvents aThl promot￿r￿S 8ryJ donate
Its woteeds COr¢L￿ research treatments for AVAls afyj fiNiir#J a tsj￿. There has been r($
R3dv)k)gi51saTha Tre3th*niikn.
The Butterfty AVPA tharty 0￿¥￿je5 its a¥rfal￿. AS￿ 11*1 dre￿5 bs fft Il* thai or* day all their
efforts c¢me leadw *def¥thtr•aknr45 arKI a ¢)Jr

I￿TtERFLy AVAI c￿lARITY lIM￿ED
RE
Q.F_THE T
OR THE YEAR ENDEO 31 MAY20
OWECTf¥ES ￿IDA¢TmnEs
Signthunt a¢tiYiUes
8ullertty AVM Charity hJ5 UCL£OS AVKI RtsEarch team wluch 15 based ai
Ur￿￿Er51ty CoLiege LoTrS)n IUCLI. G￿31 orr￿ sl￿ IGOSI. Ir6b%￿8 of Htsmh arys Ihe Fraws Crith Insffithe. 1&1
by rk Maaw P￿￿b)l￿j aThJ Pnjfessor VerwKa TrQrtsipr. as L¥a￿9 ¢Xrf Y￿th Lxjr I￿aIrS re5earth 0Tr1 ayreeifvJ
a g3nl of £105.SW The Royal Free NHS (vryuW) ￿￿71h the VCL The projea 1$ liued
'Ddwbffj Mc4eoJL8r CelLlafMethar#srn5 In Va$r￿r Ktsrfomiatr)n5". This wojett in May 2025.
ai thtr Urd%Yrgty of Ethnw GÈr*s C8ror ¢0 retJL41 tr 8 bLrttsrtly AVIA fuNkd kY)5Wo&oral
reSea￿tr. Ths 8ddOmHI rese3id*r ¢mbark tyi an projea sueerwy cl ¢ngs on AVM 2ebpT6h
o1atxy8bon￿Itte thNver5ity of Edth￿. Tr L¥)5tof¥Mstu￿ t￿ytarp￿rK*j¥mll te £179.n7.
The ow ol Ilxs tesearth is"W sc¢ÈerriroJ ol carter <nB5 Y¢ AVM zeW*h" Z•bRf¢sh for
the ainof rat*Jty i1er4fyry bèatrne￿ trAVM.'
r*¥tfe4¥yea4
al U¢LGreaiOrrfthJStreet Cthj Heamhin W2025.
parents rf¢hthJreowOhAVM aTr125 ¢lMk1ww*hAVM.
SUFP)
Rou P40&). %vh) k* k) yeaf of Iw 8uttwfy AVM Stthtshp h3$ surc45sIL4ty ¢kn*opJ r*w ger￿tiC
thèrapws 1orAVM,￿tr• akrtlts I3test•Jwartw ￿ger￿￿ UknF*5 it) tre8bnents AVM.
tsr9eied treatrrwts cen ￿. In f*ièl yeÈr knil ¢0 Lrylertake a DANJ
Scr8efWg ￿ a Cellu￿r ol KW.tkNen Mawomwws ro these in an OWKI
nk*81 of WS AVM.
To our k￿. Sl¥Jy k5 tre fiTrE b Fwfvm hw￿￿1￿Jxrt In an e￿OI1￿1&01 cen fflodel ol AVM. Ths
research Yrtl demor6vats >bty) sryttrth3 da18 carKw *ll br￿ harbouriry Ihe same KRAS on
partoty of an ￿ wro screen an AVIA to ￿rflore￿ in eeu type
Roh wi¥ Ihen u¥) on kn thWJfy Fcod e appffjved sjrw In Ihe ￿ %itrD ￿￿en th¥1 hove rv)I
been lrie¢ as veatrnprts&NAVMarkl thai eaTh bo iak•nknrf knrIeS￿ npaberrtcel S￿s aThVor in athl￿ mode&.
owrK KW Va￿rt%. has d•7k￿bare0 of 8ne1tr5p￿t 5mag IntsrfenThJ RNA 35
Iherapoubc rfet)ts for C0Th11)￿S. swi foThvard. an orttK)wnal 3PPfoath to WgÈled treakn¢nl
usr4 smau rtrf¢riffj RNA5¢Je5¥wed v.
P&x2

EP
RT
TKET
FOR ThE YENA ENDED 31 IIAY202
OBJECTIVES ANDACTivmES
part of new co¥akntion ai VTh**W d E01￿J￿h. F￿￿r￿14. effed ol the we from OLY pu￿￿he
dewewg be a ￿fe Iherapy ￿ the knJer rp
kTh)YAe6ge in tlis ar•¥. V+* ￿ rwini speoft célL*w p*w 1101 raft t* larg¢ied to or Polenl
immateAWs.
deiaw CortL￿r map of Avhts. 71#5 mop ￿ reveal rfftJarui*n 8f¥J suprK*i the deveW)Of4 ol tsr9tled
ther3wes. fx* fUr￿lThJ has akntd Royal Free Hoswral thrs mi￿SWIn0. fi0311Se and
We Iwe th• ol a weahh (Pffjf Jaw Tw. Ilr Clw sm ￿m. Pmf thXe￿ Br¢okesl wrKhJ
leadirg ￿￿¢¢￿01 sc*htsts {P￿r Mawè Pwf 88ithrMI Its er6L¥e the suc£￿ woject ond lis
tra￿lat￿)n ¢kn¢.
chrtW dtsease arby ￿ wwrtarKe of srveas*J reseath dwa%es by trjlh iha t>Jverr¥T¢ni ar
ma￿￿tKa1 comparites.
is 8ts0 ￿ Ihe GLirww ivjk ol Records as é%v of the 8AFfA3 sp￿1 IrK thanty
is also an &th)r. off W*w. fa¢¢5 was rec*th 10 latk al
Nakn in Ger*¥a lo fai¥ &Ya¥erw art¢ a￿j 15 n>)Y*vJ the kn¢fen¢s5 of Iha
OL* raty of A￿ts aThl fv IKk of tss ¢0 m810 8 C￿rted effort to prov
sufferets an ytty•ale %vebsrte rrfyw been u￿ated make n rnre iESP)nsve arvj u50rf(*ndty provKIÈs
a seML* to rfoo*fam*s tho btssttrea￿ts arxj Iw ra6&J aKar￿*s$￿ on a￿Jme h¥h.
Tho I￿lee$ hav¢ gwen ¢kn rewd io gLwJarth ty the ahirty ui Yhwi thv £h8nty
$ro￿d v￿e￿￿k*. oimpw Iho rjuty ￿ Sea￿ 17151 orth8 3)11 Cttariies Ad ￿ have (Jue regard to
guK18fK4 wbltsw bylJ* c0mmw￿. Detats ol ￿thE tharity¥ *e ale ¢elailed
Gr4n¢maklnB
wayol a gonL

THE_NITTEBFLYAVM￿.HABIYYL1M
RepoRT
FTHeTr
NOEO 31 MAY2025
FINANCLAL REWEW
R•Sor￿ pollty
11 Is ttte ol thè • Ihat ILwhts t*¥e been ée5VJna￿l speok w 5Wd be m￿n￿￿e0
81 a level eqvNa￿nI lo ttheeft lI￿e aTr1 st< rronth3 •lmvH51r3bve support eXpe￿A￿e. The trltsiees o)AswJÉ¥ th81
feserbw al kns *1 eftsula ¢hal. kn the 8venl ol a s￿￿nI drop in Iwxlw. Ihty ba fo (*nbrwe Ihe chatsys
tutrent acmies cw6¥Jeralw 15 to Ytay5 in fth15 may be Tts k8b*i of re5eTh*s hès
General unresirtthd fL￿a £154.746
[￿$$nated SJTrJ. R8se4rth £171.7
twnaied ￿￿￿.To8)I￿L £30.O)J
$0 gtaiefiA fol ts genEffjWS *9xry donal1￿ of G￿ffreY O• aTrJ R￿se1 *il h￿￿ our or¥JD',r4J
Al tr*eTrJdth8 y￿. wwas* &Thfi￿￿￿1l￿peI>￿￿8$ £139.140
the ￿%?r il* thaThty of £78.16? n &Jdti)n to C126.CW taltrw from v* ￿l￿b￿l￿n$
fromG&Jffw oartya￿ JoRl•i RLs$￿L
furtboThrg aryl sithYardslMpolth&dwrty.
STRUCTURE. GOVERIWICE AND MAIIAGEMENT
Go¥Yml•9 dtscurr•nt
The r5 a compaty guar3ntee. as by tts (knrMe5 11 is wnwoaed by its g)vwnw
Nor* of the Tntsiées ha5 arry L￿erK￿ IhE ihe t(￿le￿$ we w*mbw5 of thg company and
9varan*ÈtOWlWèute £1 8*ni ¢fa*?￿l¥j Lp.
MrG (kni5ts¢jWa￿￿aI m¥*9vol￿d*rty.
REFERENCE AND ADMINISTRAnvE DETAiS
R•9lsto1od Company r•w#bor
OW61944 **Wa*sl
A•gi¥t•r•d ¢b•iilynLNnb•r
1149170
869 Hyh R
Noth F￿Y
Lorthn
N12 80A
Poge4

REP
FOR TH
RTOFTHET
_YE4R ENDEO 31 MAY
Trwt••s
Mi G S Gery9*)u ￿red
MrK PeriftyTK>U Owior
Indoperyl•nt Examln•r
Mr Phirporissipl￿oUbA(knTr FCCAFCA
G. GeDfgeAssooaies
12 G81*rny￿th$
Riryway
LwJon
N11 2ur
5 reptsrt h35 baen wwared *) acuthrte sp*ial of Part 15 ofthB CornpariÈs P4 2Ct)6 10
smaUc0Mpar￿.
ts bBWty.
P•J8 S

THE 8urrERFLY AVM CIIARITY LI¥￿E0
Ind•pondgth•x•mtiv*fs wwrtfoth•tn￿t¥￿ ofTh• Bult•rtty AVM CharityUmlt•dlkn Compan
I repm to Lhe ￿nW￿ls￿e5(￿myexaMlnètsnQ1 theactourtsol theC•rtySJr 31 May2W45.
R•spon51bfjUO•s4ThJ l>a81sof fewt
As the charivs orth¢ I￿1 also for ts P￿￿505 ofo)mpary l•wl ytsu we for I
trla%ir¥ saitsfibj rnyself that ihg 8¢<thmts oftr* Gynparry •t w retymrpj lo te Pad 16 of Ihe 2C#]5 Aa
afe elgitslè lor i￿ep￿errt &yarwobon. I rewrt in w ol my ol wur dHnly's actounl$ 8s ca￿1ed out
utsJer Secith 145 01 th¢ Charths A# 2011 2011 Adl. raff￿r￿j tyjt my ex8Mifw￿ I have foJW Oire￿￿
gwi by Ilje Ch*ty Ccffjw¥ssi)n 145(51 lblo1￿ 2011
Ind•￿Tra•nt oxam1n0￿8￿￿t•rnertI
I lyave compr¢tsd my exèntrna￿n. I thai ￿ rna￿&￿ rme * my wth the eyaminai
gNirs me 10 b￿￿..
acwL*ts ¢Jo ￿ t•mpty *ith th• acox*thJ wwemÈnLs of Sedw 395 01 Ihe 2rths Aci olher than any
urerr*ni that a¢coLmts 9¥* ¥ tNe r*¢ ¥ OYL5AJered as part of an I￿8p*¥JenI
0?￿4*￿e %4ith tha Fvwoal Reporiry sAard•5 aptA¢4￿1n thfyVK Re￿￿Ortr￿S IFRS 10211.
(Iw•n inlhis reKort uioroer￿0n0tle a pMporyThlefsi￿l￿Clthfr 8c(£Kwts reachpj.
MrPfv*&l55iF￿ FCCA FCA
12 Gaie¥rayV
liw Way
L(%￿On
N112UT

FOR THE Y
ENDED 31 MAY2025
7024
Yo￿1
hJTrJs
Tolal
INCOME AND ENDOV4NEMfs FROM
¥M.162
204.182
172.665
6.692
5.317
Total
210.854
210.854
177.W2
EXPENDITUREON
Ra￿r￿j fur￿3
1470
2.470
55.816
69.244
69.244
029
Totsl
71.714
71.714
123.845
NET INCOME
139.140
139.140
S4.137
RECONCILIATION OF FUNDS
21Q862
216.8F2
162.725
TOTAL FUNDS CARWED FORWARD
356.002
216.862

BUTYERF.LY A￿m_¢){ABWr￿y
BALApKe SHE
31 MAY 2025
2025
Tothi
2024
To¢al
f￿5
CURFIENT ASSEYS
e25h olbankard inh8r*
9.313
9.313
346.689
216.862
356.￿3
216.e62
NET CLIRREiif ASSErs
356.1)J2
216.W2
TOTAL ISSETS LESS CURREp¥f LIABILFfiES
216
ET ASSEYS
216.862
FUIIDS
10
General
154.746
171.256
51.862
135.000
30.000
Oesignots6 ￿￿j.￿1kkn ¢)Y$ty)vT￿akn
216.862
TQTAL FUNDS
216.862
The tharira¥e mrrwty 15 b) ox*)W kom 477 of ALI 2TrJ6 IDr ￿ year
31 Uay202S.
The membe15 have Thji requrwj oyrparty ¢0 oLtsn ￿ pAA1rt of15 fl￿)$ for the year eTrJ8d 37 èAay 2025
Cornpan￿$￿I2￿6a
kYepaDry [inaT￿￿ 518ienwrt5 TA*th ￿ a tsir %iÈw of tho s&te d aff*5 ￿ the rJ*ntatye cfjmparry as ai
erf ofeath year arrfj ol rts gJ¢pts efdefpx lor exh fina￿lar ￿ar fft 8t0)￿ar￿ the reQU￿rne￿$
Ibl
MrG

TAYEMENTS
R TrIE VEAR ENDED 31 MAY 20?
ACCOUNTWIG POUCIES
B*$1501proparing th• flnlrtcial statsm•n
rwroal ￿1￿4116n1S ol the ctsrtsble (Lryarry. be￿ enlrty FRS 102. have been
wepw&J in ¥Cordar￿e ChaDtits SOF￿ IFRS 1021'A￿)￿￿br￿j ard Repo1￿￿￿ by Cher￿8$." Slalerneni
SlaTrlaid lppknble in UK OTr1 RepuWK ol IFRS 1021 leffedNe 1 Jan￿ry 20191.. Final￿31 Reporbtvj
StaTrlaid 102 Tr Fin￿ Repybrg Staryjard appltatltr ift ￿ VK aThJ Rew*)k ol •)J Companios
<harity ts a ¢omparry regwe¢J UK liwed by sx4r8ntsa. Delals of Company
SsThfwt the supp>th thorty h) amual d￿r do￿. Nikki
The charitable rAwèrty *var4•30 of th& exempb)n ￿ propafft￿ fmar*4•1
Exp•thdhwe
are reow*ed 0$ won a5 ss a tryal ct4gakn mmmrtbrKJ Il* tharity
to thai exp¢rfituro. it ts wobabb L14ry1 a trarffjler of ecor*fflK ￿errf$ wil bp reqL￿ti) in seNe￿nI aThJ the amount
ol 00￿JaIl)n <8n bÈ measwtyj reti3tty. EV￿3rtU￿ r& for OTr an ￿tI￿aL5 basis ar￿ Iw5 been
rJassiW tnle( Ihai 4grffjale ¥1 C¢)5t rdaled 10 ￿ tstw. tosts ran￿1 bo dtye• aiir*xrtod
Fund •¢eourtlng
FL¥1her exr4anawJnol Is ￿J•1¥+I1? r¥tes to * fmano* $k￿MEnts.
•ji￿led BS write tsansQ￿￿ FRS 1WI
¢)jntifi￿...

ThE 8iTrrERFLY AVAI
Rlfy
ELUIEAR ENDECI
1 MAY202
OONAnONS ANO LEGA￿Es
2025
Tofal
2024
Tow
luThl5
78.102
126.CbX*
78.162
126.000
172.665
204.162
M.162
172,665
INVESTMENTINCOME
202S
Toial
2024
Tow
fuThJs
6.692
6.692
5.317
RAISING FUNDS
20Z5
Toiat
luThJ5
2024
Total
furMJ5
r¥J5
53.S57
2.259
2.470
2.470
1470
2.470
55.816
GRAFifs PAYABLE
Y)25
2024
69.244
68.029
31.S2S
31.5.24
69.244
68.029
04 Juty 2WL4
22A￿j￿ 2024
1 l N(wember2024
11 Novemb¢(2024
18Jarwry 2025
22 Awd 2025
Oi W3J25
£5.155
£5.156
£27.147
£5.049
£5.244
E13.0>)
P•Je io

ThE ￿￿TrEItFLy AVM CHA￿.l￿.[￿ED
EQ.R ThÈ YEAR
TRUSTEES. REMUNERATIONAND BENEFITS
14DED 31
Th9rè ￿￿e bomfts lor y•ar ￿J?) 31 Nlay 2025 ￿ for year endvj
31 May 2024.
T￿rnwel¢ tK) ￿￿*$'e￿￿e5 ￿lIf0r1￿ >e8r 31 A4y2025IKY Y4areTrj￿ 31 May 2tr24.
MATEft￿L T11411SFERS
Atran51¥ was ￿je￿Ike￿ olE1D5.s￿ Imm thè knNI b tre I￿1 of VrMvw5ty Colbae LgThlon
Ifor resparth grnnl5.
¢OMPARATI4ES FOR THE STATÉMÉiif OF FINANCi4L ACTivftEs
Tobi
INCOME AIID EI4DOYaryAEN￿ FROM
D￿J￿r6 aThJ Iws
172.665
172.665
5.317
5.317
Tot
177.982
177.982
E¥PENfATUREON
SS816
55.816
Rese•fth FUThj￿. r*s¥￿ted
Tot
69.029
123
123.845
NET INCOME
54.137
54,137
RECONCILi4MON OF FU140S
162.725
162.725
TOYIL FUtr4DS CARRIEO FORWARD
216.862
216.862
DEBTORS.. A¥OUNTS FALUNG OLIE7hwfHIN ONE YEAR
2025
2024
9.313
)nwwed...

THe BUTfERFLY
FOR THE YEAR E140ED 31 MAY 202
10.
MOVEMENT W FUNOS
Nel
Tra￿
Al 1.624
At
31.5.25
lu
Genwai iuTrl
51.862
135,0
2Ce.384
169.2441
1105.5)JI
105X
151,746
171256
216.862
139.140
.002
TOTAL FVNDS
216.862
139.140
M0￿ment
Gewal f
210.854
12.4TOI
169.2441
169.2441
210.854
139.140
TOTAL FUNDS
210.854
171.7141
139.140
Net
11.623
fur
31.524
Genwal fw
57.725
75.fK#J
122.166
(68.0291
1128.0291
128.029
51.862
135.oc
162.725
54.137
216,862
TOTAL FUTr•OS
162.725
54,137
216.862
luTrJs
UNgsirfGt•df
Ge￿1￿ f
17T.982
155.816)
168.0291
122.166
168.0291
177.982
1123WI
54.137
TOYNL FUNDS
177.982
1123.8451
54,137
P•Jo 12

THe BU￿ERFLy A
TATEM
E YEAR ENDED 31 IIAY 2025
R TN
MOVEMEMf Jpi FUNDS. ronllrn*d
At 1.623
ILnds
I￿r￿S
31 5.25
GeT￿ra1 I￿ry
57.fd5
75.C
12315291
233.529
154.746
171.256
Deswated fL¥xJ. N￿k1 Treabnert
1137.2731
162.725
193.277
256.002
TOTAL FUNDS
162.725
193.277
356.002
V4)vemeni
De5gnaiedftJ￿E.vth•mtyCAll&3P LoTrJJn
158.2861
1137.2731
1137.2731
1195.5591
193.277
TOTAL FLINDS
1195.$591
193.277
Th& Un￿￿Y Loth Iles03rt* FI￿ Qeai Om¥)TrJ S¥ed Hwprt•ll is 11* 9r*i payfflen
Nthki iLrf i5 kn 8 fv lor fvrttw org)irvJ tsEa¢0￿ on Nkki AVM
0)Tr1itti1.
Trnnsfero b•l*wn lur
A Iran5fer was byeed tru5W sn the fin¥K3al year ol tI05.5C*) fmm 9eneTrl fuTr1 lo
Dessn31ed fLWKI to rover rfjseatch L4)l&iaken AVM Corfition C4iw LO￿On
G￿[orMC￿￿ Y1* b8lttrf*ol¢hs Dwthj firtl al the Yeare￿I￿a$ £171.256
OTHER FIN*NCIAL COMMrfMENTS
The cjwnty has a commiknei* b) pty re5eath Inkn V* AW tyjrbjitw. £171.256 h85 bE¢n ¢esKJnated tsr
2025 to 2028
Pago 13
o)nbnug9...

THE.BLrrTERFLY AVA4
-￿HARITyLI￿ITEI•
THE FI
FOR ThE YEAR ENOED 31 MAY 202S
RELAYEO PARTYDbSCLI)SURes
Py14