Christopher'8 Smile Coz tid3 8et cancer too Trustees, Report th for year ending 30 April 2025 Our vision is for every child diagnosed with childhood cancer to not only survive, but to reach adulthood enjoying a good quality of life. Charlty Registration Number 1129x16 Trustees Mr Kevin Capel Mrs Karen Capel Mr Denis Conroy Mrs Rosemary Conroy Principal Office 10 Ivy Drive Lightwater Surrey GU18 5YZ Bankers HSBC plc 29 High Street Camberley Surrey GU15 3RE Website www.christo herssmile.o Princlpal ema51 address info christo herssmile.o Trustees Report for year ending 30 April 2025 Introduction to Christopherfs Smile In October 2￿6, Christopher Capel then aged 4 wa5 diagnosed with Medulloblastoma, an aggressive paediatric brain tumour. Following 21 months battling the disease Christopher bst his fight for life in June 2LX)8. nine days before his sixth birthday. Christopher was the only child of Karen and Kevin Capel. Following their tragic loss, Karen and Kevin Capel wanted to help children with cancer in the future by funding reseafch into new treatments for childhood Can￿r. Background to Christopherfs Smile- Chrlstopherfs Smile started in October 2CNJ8 and was registered as a charity by the Charity Commission by a Declaration of Trust Deed dated ioth May 2009. The charity ralses funding exclusively for paediatrlc can￿r research WFth a bias towards the development and approval of genomic diagnostics for paediatric solid tumours. Christopherfs Smile has a firn) principle that every penny of a donation should be used for the cause for which it was given. The charity has continued with this principle for the financial year 2024- 2025. Aims and Objectives After Christopherfs death, we wanted to make a difference for children with cancer in the future. AFthough there are many charities that raise funds for different aspects of childhood cancer we saw the only way of breaking this terrible cycle was to fund research. We had seen first hand the efflcacv and side effects of current treatments both in Christopher and the other children In the Royal Marsden's Children's Oncology ward. We learned that if a chlld SU￿1Ve$, their Ilfe and that of thelr family is never the same again. It was these memories that led to our charitys vision: "Our vlslon is that every chlld diagnosed with childhood cancer will not only survNe but reach adulthood enjoying a good quality of Itfe." Thls vlslon has been translated Into our charitys objects as: l. Provide funding to non profft makin8 research or8anisations that hjrthers research into paediatric can￿r5. 2. Raise awareness of the needs of non profft making research organisations that further research into paediatric cancers. 3. Raise awarene55 In ihe 8eneral population of the need for fundln8 the research Into paediatric cancers Christopherfs Smile is a tsrget based organisation. We made the decision to set a fundraising target in order for our supporters to know what their money is to be spent on. We also believe that a charivs funds shoukl be spent or allocated the earllest opportunity. Christopherfs Smile continues to hold the following set of values. When V￿ started the charity we decided to adhere to a set of principles which we believed in and which our donors would respect. > Every penny of every donation woukl be used forthe cause for which it was gtven. > Costs should be kept to a minirnum and we do as much ourselvesaswe can. > Where we Deed to buy in products or expertise we vmuld control costs vigorously. Every donor or supporter should be shown exactly where their donation has been spent. > Build a relationship with donors and value every donation no matter how small. > Ensure that funds are spent in the best way possible to get maximum benefit from them. We set these objertives for our first year and our aim is that they will remain in place while Christopherfs Smile is Still needed to raise funds for childhood can￿r research. Paediatrlc oncolo￿ Artlvltles and Infiuentlal Factors May 2024 - Aprll 2025 The year has seen leaps forward in DNA sequencin8 technologies enabling sequencin8 unit costs to reduce while the abllity to sequence the smallest amounts of DNA, hitherto not attainable, is now achievable. We still do not have an NHS approved liquid biopsy test for paediatric non CNS solid tumours. We are still waiting on the NHS Genomics Unit to approve this v¢tal test. Chrlstopherfs Smile funded a Proof of Concept {POCI project for the detection and analysls of Brain Tumour DNA in the blood. This project used the very latest technolo8ies and if Suc￿sSfUl a full scale project will commence. The Charlvs prfmary alm Is to fund tFe development and testing of a paediatric CNS Liquid Blopsy test. This is because we see that a non-invasive test for paedlatric CNS tumours 15 an area of the highest unmet need. In the year all four trustees have had significant personal challenges to address outside of the charity. This has meant that the trustees. focus has had to be elsewhere resulting in les5 time being spend on charity work. We hope that in the forthcoming year the trustees will be able to spend more time of charity artivities but we know we will not be able to devote the same amount of time as previous years. Fundlng future Prolerts The funding of a Proof of Concept project has allovftd Christopherfs Smile to ascertain whether current techrK)logles and techniques are 5Ultable for a usable liquid biopsy test for paediatric CNS tumours. The two techniques currently being tested are under constant evaluation to gau8e whether further effort is worth Investment. There is also an exciting advancement from Australia which the trustees may in time need to consider is worth an investment in testing within the UK. The trustees will monitor progress and assess the viabiltty of investment. Income for year endlng 30th April 2025 £24506 Cost Offset £4571 £1368 Incomefrom events Donatlons Sponsorshlp Grnnts GiftAid Interest. Re5tiirted donotion5 qnd qronts specljlcolfyforcost £107 Running Costs £207 Card transartion fees £601 Cost of events £24399 Net amount after costs £24364 £767 Profitfrom events Net Donations Sponsorship Grants GIftAld £4,567 note £34.913 Availablefor researchfvnding Decrease In restrirted and designatedfunds below Note". £29,637 was transferred from cost offset to research funding and 195 was released from amounts paid by solicitors. Please see the Notes to the accounts for full detsil. Financlal revlew Highlights Total receipts were £40,445 with unrestricted receipts of £15.939. Restricted funds mainly comprise donations from the trustees, donations from solicitors with time restrictions on them moving to unrestricted and Interest retrivable. t)onations from the trustees and interest receivable are used to cover the running costs of the charity. Designated funds are amounts donated to the charTrty for specific purposes. Amounts paid into the restricted funds exceed costs by £24;399 this year. When added to amounts brought forward from last year this Elves a balance of £32,398. This balance comprises £1.629 from solicitors and £30,769 other restricted income. Restricted costs have been runnin8 at around £200 in previous years and this year they were £4107. It has therefore been decided to transfer £29.657 from restricted funds Into unrestricted funds. An additional amount of £195 has also been transferred to unrestricted from balances received from SO1￿ltOrS leavinB a balance of £1.134 included In restricted funds and this is fully described In the notes to the accounts. All clothlng costs are included in restrirted funds as most of the clothing bought is glven to people who a￿ competing in sponsored events to raise money for the charity. Any sales are made are at cost and the recelpts are added to the restricted fvnds budget. Restricted have been at a very low level for the last few years and are more than cover by donatlons made by trustees. The trustees have decided to move inlerest re￿1vable from restricted income to unrestricted in the accounts strin8 With the year 2025-2026. Total Funds costs for Charltable Glvln8 Total funds avallable In Un￿$triCted funds as at 30 April were £51515.950. GIftAld Gift Aid on sponsorship and donations totalled £2,047. Reserves pollry The reserves policry of Christopherfs Smile is to maintsin a balance on unrestrlrtive funds to cover any commitments made by the charity. As at 30 April 2025 the chartty had commitments of £46.IXJ). Publicity and Social Media Christopherfs Smile ha5 continued to use social media as a platfonn for communicating Its activit￿5 to supporters. Christopherfs Smile has a Facebook Page.. htt www.facebook.com Christo herssmile Chrlstophef5 Smile also has an X a¢¢ount (formerly Twitter accountl= htt twitter.com cozklds Statement of Public Beneflt We contlnue to fund research Into new treatments for chlldhood cancer. We maintain that our research must beneflt as many chIld￿n diagnosed wlth cancer as p055ible regardless of their rao. nationality, sex or reli8ion. For us all lives matter and we wlll ensure that our funded research and activities beneflt all children dlagnosed with cancer. Trustee Message The trustees are increasingly frustrated at the speed of approval and implementation of the Ilquld biopsy tests for children. We will continue to campalgn for change to ensure that Implementations and ownership withln the NHS for implementations actually do occur. Our objectNe in all our campai8ning activities is to improve the outcomes for chlldren dia8nosed with cancer. The trustees of Christopherfs Smlle are as committed as ever to enable the introductlon of Innovatlve dlagnostics and t￿atfflents for children dIagr￿Sed with cancer in line with our vision.. °Our vision Is for every chlld diagnosed with chlldhood cancer to not only survive, but to reach adulthood enJoyin8 a good quality of Ilfe Mr Denls Conroy Treas rer Mrs Rosemary Conroy Trustee CHARITY COMMISSION FOR ENGLAND AND WALES ChrlstopW* Smll• 1129906 ments accounts Recei tsand CC16a For th• porfod from To lot 24 Jolh Awll 2025 Section A Receipts and payments UnrostriGtsd fund• Restricted fund• D*signat4d fundB Total fund• L••t y••r to the n•aro81 £ A1 Reeel ts Donations nsorshi Fundraisin Cost offsets Gift Aid Interest 1618 9.619 12,826 1,691 2,174 618 Events 1047 2,047 149J9 24,013 A3Pa on uid Bio Pro Cost of fundraisin Administration cost Card and Transaction fees Bank cha es ect events t4oJo 1S.080 601 728 207 93 Sub tot 15.858 107 15.988 940 15,858 107 1S,900 Net ofrecelpts/(paYM￿ts) AS Tran8lers between fundg A6 Cash fund8 18St yoar ènd C&8h lund8 thls ye•r end 81 29,657 24,399 29,657 23,OT3 51$, 618,38• Section B Statement of assets and liabilities at the end of the period Unrestrtcted Restrtcted lund8 lund8 to n•ar•st£ to n•*T￿l£ De8lgnated lund8 ategor ue1311S to n•argst e 81 Cash fund• hire Bw* Vyin Ktwrf Ctsrfty B¥th 2.439 8,677 rotal cash fun(ts 515,950 2.439 S￿ned by ontr Or trust￿ on ￿h•H of011 th• tru8te•8 S￿￿OIU1• Prlnt Namg Dale of roval l> c cO￿e Christopher'8 SMile coz kid3 8e* c&ncer too CHRISTOPHER'S SMILE JNANC14L STA TEMENTS FOR THE YEAR ENDED 30APRIL 2025 NOTES l The financial stat¢ments have been prepared using the receipts and payments b&sis for charities with gross in¢ome of less than £250.O¢XI. 2 The movement in designated and restricted funds during the year were Balance BIF Receipts Payments Transfer to unrestricted Balance CIF Restrlcted Fund Donations by Trustees Interest Clothing Sales £650 £23.856 £0 Equipment purchases Administration costs Promotional items Bank charges £0 £46 £61 Phillip Ross Credltor £1.629 £0 £195 £1,434 other Restricted £6.263 £24.506 £107 £29,657 £1,005 £7,892 £24.506 £107 £29,852 £2,439 Designated fund5 £0 £0 £0 £0 £0 £0 £0 £0 All expenditure other than the costs of fundraising events and card and transaction fees are funded from the restrirted fund. The restricted fund is funded by the trustees together with any interest received and the sale of any clothing which is sold at cost. Restricted Fund O:/ An amount of £2.1.629 was carried forward from last year in ￿spert of Residual Client Account Balances from Phllllp Ross Solicitors During this financial year £2195 was released from the total held as the six year time limf( had been exceed. At 30 April £1.0434was held as restricted until the tirne It could be ￿ClaiMed has passed. Restrirted costs were £107 this year due to the low level of expenditure reducin8 activities carried out by the charity. In pre¥ious years costs have been runnin8 around £200 the Trustees have decided to transfer £29.392 unrestricted funds. The amount held in respect of the donations from Phillip Ross have been ring-fenced and are not effected by this ￿leaSe. io CHARITY COMMISSION FOR ENGLAND AND WALES Independent examiner's report on the accounts Section A Independent Examiner's Report Report to the trustee81 member8 of Christopherfs Smile 30th April 2025 Charlty no (if any) 1129906 On accounts for the year ended Set out on pages I report to the trustees on my examination of the a¢¢ounts of the above chanty ('the Trusf) for the year ended Ro8pon8lbllltle8 and As the charty trustees of the Trust, you are responsible for the preparation ba818 of report of the accounts in accordance with the requirements of the Charities Act 2011 ('the Acr). I report in respect of my examination of th8 Trust's accounts carried out under section 145 of the 2011 Act and in carying out my examination, I have followed the applicab￿ Directions given by the Charity Commission under section 145{5)(b) of the Acl. Independent I have G(Knpleted my examination. I confimi that no material mattérs have examinerfs ststoment come to my attention t0tt￿F￿-C￿￿r) in connection with the examination which gives me cause to belTreve that in, any material respeci.. accounting records were not kept in accordanca with section 130 of the Act or the accounts do not aCc(￿d with the accounting recL)rds I have no concems and have come auoss no other matters in connection wrth the examination to whth attention should be drawn in order to enable a proper understandirKJ of the accounts to be reached. ' Please delete th8 ￿￿KdS in the brackets if they do not 8ppIy. Signod: Date: 15-Iic jo Name: Relevant professlonal qualification(sl or body (If any): Address: FL4T I 50 IER October 2018