## **PSEUDO OBSTRUCTION RESEARCH TRUST** ## **FINANCIAL STATEMENTS** **FOR THE YEAR ENDED 31st MARCH 2024** ## **TIM HORNER FCCA** Chartered Certified Accountant 55 Crown Street Brentwood Essex CM14 4BD www.hillwooldridge.com ## **PSEUDO OBSTRUCTION RESEARCH TRUST** ||**Contents**|| |---|---|---| |||**Page**| |Trust information||**1**| |Trustees' report||**2 - 6**| |Independent examiner's report||**7**| |Receipts and payments account||**8**| |Statement of assets and liabilities||**9**| ## **PSEUDO OBSTRUCTION RESEARCH TRUST** ## **Trust information** |Charity commission number|1114217| |---|---| |Established|22nd February 2006 by Deed of Trust| |Address|Steeple Lodge| ||Church Lane| ||Doddinghurst| ||Essex| ||CM15 0NJ| |Website|www.port-charity.org.uk| |Trustees|Sue Stewart (Chairperson)| ||Rebecca Stanier| ||Barry Stewart| ||Dr Nigel Meadows| ||Lesley Carmichael| ||Ashlee Johnson| ||Kilian Fitzsimmons-Wilson| ||Sonia Frost| ||Ian Frost| ||Abigail Andrews| |Bankers|Lloyds TSB| ||47 High Street| ||Brentwood| ||Essex| ||CM14 4RN| |Independent examiner|Tim Horner FCCA| ||55 Crown Street| ||Brentwood| ||Essex| ||CM14 4BD| **Page 1** ## **PSEUDO OBSTRUCTION RESEARCH TRUST** ## **Report of the Trustees** ## **for the year ended 31st March 2024** ## **History, objectives and activities** Pseudo Obstruction Research Trust (PORT) was established in February 2006 in Brentwood, Essex The objectives of the trust are: ## 1) To promote & protect the physical & mental health of UK sufferers of Chronic Intestinal Pseudo Obstruction (CIPS), Gastroparesis & Dysmotility leading to intestinal failure, through the provision of funding for medical research, support ,education & practical advice to advance the education of the General Public in all areas relating to CIPS, Gastroparesis & Dysmotility leading to intestinal failure. - 2) The relief of sickness and the preservation of health among people residing permanently or temporarily in the United Kingdom The main activity of the Trust in the period under review has been fund-raising to provide sufficient reserves to enable the trust to sponsor future research into the causes of Chronic Intestinal Pseudo Obstruction. ## **Management and governance** The trust deed stipulated the first Trustees, who continue to serve. There must be at least three Trustees. Were there a requirement for new Trustees, these would be identified and appointed by the remaining Trustees. In selecting individuals for appointment as Trustees, the Trustees must have regard to the skills, knowledge and experience needed for the effective administration of the Trust. A new Trustee will be inducted into the Trust by the existing Trustees. This would involve awareness of the Trustee's responsibilities, the governing document, administrative procedures and the history of the charity. A new Trustee would receive a copy of the latest annual report and accounts. The Trustees annually review the risks that the charity faces. To date these have mainly related to safeguarding the charity's reserves and have been satisfied by ensuring funds are held on deposit with an established bank. Continued/…... **Page 2** ## **PSEUDO OBSTRUCTION RESEARCH TRUST** ## **Report of the Trustees (continued) for the year ended 31st March 2024** ## **Achievements, performance and financial review** During the ended 31st March 2024 the Trust's activities resulted in net funding receipts totalling £38,090 and expenditure of £419. PORT continues its working relationship with Bowel Research UK (BRUK). PORT has access to the Medical Research Peer Panel made up of leading Consultants Doctors and Medical Researchers of Bowel Research UK who review, and score the research applications we receive, so that we focus on the best possible research. In this year 2023/24 we have not made any Research funding as the applications that were reviewed were deemed by the BRUK Medical Advisory panel to be not of a high enough standard. This year has seen the passing of a valuable member of our trustee team Rachael Green, after suffering with CIPO condition for most of her life, she will be sadly missed. ## **Following on from our PORT Trustees Report Year end 31.03.23** ## **Research 1/2023 Salford Royal Hospital NHS Foundation Trust** ‘Exploring intolerance of small bowel feeding in severe gastro intestinal dysmotility, a feasibility study.’ Lead Applicant Dr Peter Paine Co Applicant 1 Prof Lal – Intestinal Failure Unit Co Applicant 2 Dr Sarah Kelly – Consultant Clinical Psychologist – Intestinal Failure Unit Co Applicant 3 Prof John McLaughlin – Division of Diabetes, Endocrinology and Gastroenterology Co Applicant 4 Mrs. Kirstine Farrer – Consultant Dietician Co Applicant 5 Dr Marie McMahon – Consultant and Clinical Lead for Nutrition and Gastroenterology **Conclusions:** Double blinded jejunal feed rate challenge is feasible in adults to help explore the relationships between jejunal feed types, volumes and rates with symptoms. No relationship between participant scores of pain, bloating and nausea, and feed rate, volume and type were observed. There was clinical utility for patients and teams who reported exploring central rather than peripheral mechanisms of symptom generation using these findings. Approaching patients with an NJ tube still in situ and shorter feed durations might improve acceptability in future studies. **Page 3** ## **PSEUDO OBSTRUCTION RESEARCH TRUST** ## **Report of the Trustees (continued) for the year ended 31st March 2024** ## **Research 1/2023 Salford Royal Hospital NHS Foundation Trust (Continued)** The Salford team are grateful to PORT for their generous funding which has made this clinically important study possible. These findings will now be submitted for presentation in scientific meetings and a paper for journal submission is currently being drafted, for the BSPGHAN (British Society of Paediatric Gastroenterology Hepatology and Nutrition) Annual Conference Meeting. ## **Existing Research 1/2022 Salford Royal NHS Foundation Trust** ‘The Effectiveness of an Acceptance and Commitment Therapy (ACT) based psychological intervention on reducing psychological distress in those diagnosed with Gastro-Intestinal Dysmotility’ ## **Salford Royal NHS Foundation Trust Midpoint Report** Ethical approval has been obtained and recruitment of patients has begun. Collect outcome data (ongoing) Collect and complete group intervention (ACTing on your GUT feelings) Conduct qualitative interviews Conduct data analysis An Initial funding grant of £25,138.01 has been paid for the Initial set up costs of this research, however due to a number of staff leaving the research project, and the main lead going on Maternity leave the work appeared to have stalled, and not been fully completed as initially set out. The final report is unsatisfactory, and at this time PORT have informed Salford that we will will not be funding any further research for this project as the Initial Final report demonstrated that the research had not been fully completed. Bowel Research UK are holding the remaining £24856.19 on behalf of PORT (Ring Fenced), this will be reallocated towards a new research project in the future, in 2024/2025. ## **Research 2/2022 Great Ormond Street Hospital (GOSH)** ‘The Utility of Motility-MRI in the assessment of Foregut Neuromuscular function in Children with Paediatric Intestinal Pseudo Obstruction (PIPO). The initial start date was September 2022. This was delayed to April 2023 due to recruitment issues. Ther revised end date will be November 2024, after which a Final Report will be produced. **Page 4** ## **PSEUDO OBSTRUCTION RESEARCH TRUST** ## **Report of the Trustees (continued) for the year ended 31st March 2024** ## **GOSH Midpoint Report** We are progressing well with our study and the first part is almost concluded. The aim of our project is to validate the semi-automated quantitative metrics of GI motility extracted from MRI in children with PIPO, against ADM and small bowel scintigraphy. It is characterized by a retrospective arm, with the analysis of small bowel motility in MRI, small bowel scintigraphy and ADM In 20 patients, and a prospective arm, which involves the analysis of the motility parameters in children with PIPO and control group (non-PIPO patients) using MRI, ADM and small bowel scintigraphy, with the aim to validate automated MRI motility biomarkers (15-20) patients) The retrospective arm has been concluded. We are moving to the prospective arm. Work is still progressing and a Final Report is awaited. ## **PORT Charity PIPO booklet update** The information booklet produced by the Pseudo Obstruction Research Trust (PORT), with the help of the Gastroenterology team at GOSH, for children, remains current and is still in use at GOSH. The booklet has provided an ‘Easy to read’ source of information for children, and their families from PORT and GOSH. The feedback has been very positive and we are proud to have produced such an informative booklet. ## **Facebook Page update** Our private Facebook members page continues to grow, it is a friendly, informative group where families can converse freely, build up relationships with one another which leads to the families feeling less isolated. This is of paramount importance to help with mental wellbeing for sufferers. ## **Linked In** The PORT Charity Linked in page has now been established. ## **Acknowledgements** PORT would like to thank all the efforts of the various fundraisers, and fund-raising events that took place during this accounting period. ## **Trust's funds** The Trust's funds are all currently unrestricted. **Page 5** ## **PSEUDO OBSTRUCTION RESEARCH TRUST** **Report of the Trustees (continued) for the year ended 31st March 2024** ## **Approval** This report was approved by the Trustees on ……………………………………….. and signed on their behalf by: ……………………………………………….. ……………………………………………….. **S Stewart R Stanier** Trustee Trustee **Page 6** ## **PSEUDO OBSTRUCTION RESEARCH TRUST** ## **Independent Examiner's Report to the Trustees of Pseudo Obstruction Research Trust** I report on the accounts of the Trust for the Year ended 31st March 2024, which are set out on pages 8 and 9. ## **Respective responsibilities of trustees and examiner** The charity's trustees are responsible for the preparation of the accounts. The charity's trustees consider that an audit is not required for this year (under section 43(2) of the Charities Act 1993 (the Act)) and that an independent examination is needed. It is my responsibility to: - examine the accounts (under section 43 of the Act), - to follow the procedures laid down in the General Directions given by the Charity Commission (under section 43(7)(b) of the Act), and - to state whether particular matters have come to my attention. ## **Basis of independent examiner's report** My examination was carried out in accordance with the General Directions given by the Charity Commission. An examination includes a review of the accounting records kept by the charity and a comparison of the accounts presented with those records. It also includes consideration of any unusual items or disclosures in the accounts, and seeking explanations from you as trustees concerning any such matters. The procedures undertaken do not provide all the evidence that would be required in an audit, and consequently no opinion is given as to whether the accounts present a 'true and fair' view and the report is limited to those matters set out in the statement below. ## **Independent examiner's statement** In the course of my examination, no matter has come to my attention: - (1) which gives me reasonable cause to believe that, in any material respect, the requirements: - to keep accounting records in accordance with section 41 of the Act; and - to prepare accounts which accord with the accounting records and comply with the accounting requirements of the Act have not been met; or - (2) to which, in my opinion, attention should be drawn in order to enable a proper understanding of the accounts to be reached. ## **TIM HORNER FCCA** Chartered Certified Accountant 55 Crown Street Brentwood Essex CM14 4BD **Page 7** ## **PSEUDO OBSTRUCTION RESEARCH TRUST** ## **Receipts and payments account for the year ended 31st March 2024** |**Receipts**
General donations
Internet donations
Website commissions
Net fundraising proceeds
Bank interest received
**Total receipts**
**Payments**
Contributions towards medical research
**Expenses**
Public liability insurance
Computer and website costs
Sundry expenses
**Total payments**
**Net receipts / (expenses)**
Cash funds brought forward
**Cash funds carried forward**|**Year**
**Year**
**ended**
**ended**
**31/03/24**
**31/03/23**
**Unrestricted**
**Unrestricted**
**Funds**
**Funds**
**£**
**£**
13,294
11,469
18,808
17,078
78
115
400
2,079
5,510
1,974
38,090
32,715
-
-
-
-
151
297
90
245
178
43
419
585
37,671
32,130
252,978
220,848
290,649
252,978| |---|---| **Page 8** ## **PSEUDO OBSTRUCTION RESEARCH TRUST** ||**Statement of assets and liabilities**|||| |---|---|---|---|---| ||**as at 31st March 2024**|||| ||**2024**||**2023**|| ||**£**|**£**|**£**|**£**| |**Assets**||||| |Bank account balances|290,649||252,978|| |**Liabilities**|290,649||252,978|| |Accrued expenses|-||-|| |||290,649||252,978| |**Net assets**||290,649||252,978| |**Reserves**||||| |Unrestricted funds||290,649||252,978| |These accounts were approved by|the Trustees on …………………………………….. and||signed on|their| |behalf by:||||| |………………………………………………..||||| |**S Stewart**||||| |Trustee||||| |………………………………………………..||||| |**R Stanier**||||| |Trustee||||| **Page 9**