2023-03-31-accounts

MULTIPLE SCLEROSIS TRIALS COLLABORATION FINANCIAL STATEMENTS FOR THE YEAR ENDED 31 MARCH 2023 Registered Charity No. 1113598 Coow P•rry Advlsory Lintd Ai$sda 46 High Str8et Esh Surrty KT10 gjy

MULTIPLE XiEROSIS TRIALS COLLABORAnON FNANCIAL STATEMENTS FOR IHE YEAR ENLED 31 MARCH 2023 cO￿rENTS PAGE Legal and 8dmlnlstrp￿ d•tsi1s Rowrt ollh• Tmst•tss Inde￿ndant Examinerf$ R•port Slal•merf d financial •th"vtts anc• sh0•1 Notes to th• fin•rK*I statew￿rtS

LEGAL AND ADMINISTRAIIVE OETAILS Tru8ta•s Je￿mY Chthay. Ch&mwn Omar Malik Rithard Nichola5 Addr083 10L18 Charing Cross awnpus Iwial Ctho¢ London Fulham Pakn Road Lcffldon Ch•dty Numb•r 1113598 Accountants ind Ind8p•nd•nt E￿MIn•rn AJ"$s•Ja 46 High StrMI Esh•r Surr•y KT10 9QY

MULMPLE SCiEROSIS TRIALS CJnl•d to £264.78612022.' £213.4461. All resour¢85 •xpended durry the y￿r werg appli￿ fft acC￿￿ne0 wilh th• obl￿tiVS of th• charrty. rv•• Po 1¢ Th• charity hAs Very few frx•d ov•rhe4ds r•quir¥$ limrfed r•serves. Ils (yjrrnrrt Foly is ts h￿d unr•strfcl•d, ￿delIg￿t•d r•seN•s $uffici•nt lo cov•rlhree morths op•rational 4Xpe￿rtur•. Th• the yo•r at the y•ar end hav• b••n in Un• V+ith this polKy. •t•••' rn• on Ibllltl•s •ts Tho trustees ar• rtrsponsiblo loi Fxty•n'ro Ihg TrustMs' Annual Rewt and $thtem•nts in K¢ordaru vrilh appllcablè law and Unllld Kingd¢)m Attounts'n9 Stsnd•rd¥ Iunlted Gener Accepted AKountsrvJ Prnclk•}. The lth¥ appllc4bl• lo chathrtss in Enolnd & Vvabes f•qLfrires th• trustees to P￿pa￿ finar￿￿) slalem•nts for ••¢h fin•rK5al yearvthic give a tru& and f8ir viw4 of the stat• c(8ffalrs of th•nty and olthe ir￿Ing r•sourc•8 and apWi¢atson of rejowcos Of tha ¢•rity lor that poriod. In pr•paring thesé finanoal stat•merds. th• we r•quire¢S to.. seloct surt•bl• ￿cOun￿n9 then OPFty tham C￿￿18¢•n1￿'. obseN• the rnethods and princ4ple8 in the Ch8nls SORP". mak• judoemenls and •51imates that are r•asonabl8 and pmdenf. Siale applicab￿ attounting Siand8rds have be¢n foltr•d. Sub￿ lo any matertgl deparbJrn8 di5closod and explained in tho fin•nrAal statements.. prepare the fin&n¢ial statements on the gckna concm basil unless It inaFVOWe to prnsumè that lh• charity wlll ¢ontlnu• in 0￿rat￿> The tNste8s are re$pffisible for k•¢ping pmper ￿untIng rffords that disdw r•asonable a¢oJrary at any time the rrna￿111 position of th• tharity And onable them to ensure that the ￿l￿tal stst¢ments Ctynpty wilh the Charityes A¢J 2011, the Chalities (A￿oun￿ and Reports) ReguWions 2008 and tha provi&ons ol the trust deed. They a￿ also resports￿tt for safeguarding tb¥ assats of the charity and henc& fortaking reasonable steps for the prMrth)n and detec*)n of fraud and othw irrngulaiilies. This report syasappmyod by Lvdw rlth• Poard on Aprd2024 and 3wed on its b•haW by". R Nl¢holas {TnJ8t••)

INDEPENDENT EXAMINERS REPORT TO THE 7RUSTEES OF IIULnpLE s¢￿0$1s TrIALS COLLABORATION report lo tha Cha￿ty trust￿ on ow ex•ninion of th• acrounts ofthe tharFty forthtr year ended 31 March 2023 whth 8re sel out on p8ge$ 4 to B. R•8ponslbilili•s and basis Of rEPOrt A$ the ch8r¢ty's tnKWtees yw aro resportsitts for th• ￿yeParatK￿ ofthe ¥xowrts in attordarK with thts requirem&rrts ofthe Charities Act 2011 {'thg Ad'} We report in rnsped of my 6xa￿n81Th of Ihe tharity's &rcounts ¢arried tyjt undw section 145 d the Act and in carying oul our xamlnation ￿ hav• followed th• Dwgctim gfven ty the Charity Comission (Thler sedion 14451{bl of Ihe A¢t. Indèp•nd•nt •xamin•rf• 4ttht•m•n¢ hav• compl•led Our examinath)n. We ronfim that ￿ mth to ¢yJr allenlion ￿ COnn8¢th￿ lth the ex4minab.on glv s caus6 to believe that in any materid r•spect 8c¢ountln9 records w8r• not k•pt in rnsped of th• tharity 05 ￿q￿red brf seLkx 130 ofthe A¢l.' th• accounts do not acconl V•ryth thosè f￿￿$. or th? ac£ounts do not Ccrfnp￿ with apPl￿ble Mquirements C0￿MIr￿ th• form •nd cont•nl of ac£ounts sot out in th• Charities (Accounts Reports) Regulations 2L)J8 olher than any rwuiivmont Ihat t￿ xtyrrts a 1r￿ and falr vlthrf whith is not m•tter¢onsld•red as PArt of an ind•pend6nl •xaminth"on. We havo no ¢onc•m8 and have come a¢r03s no othar mattw¥ in conne(on with t￿ ex￿1nation lo altention •ho￿d be dr•wn In IINS r•port in Lyderlo •n•bl• a prco•r und•rstanthw of th• wunls to bo r•Kh8d. Coop•r Parry Advlw Llm•t•d Aissel8 46 High Slmot E8hèr Surrey 10 9QY Aprfl 2024

IIULTIPLE SCLEROSIS TrIALS ¢￿BORAT￿)N STATEMENT OF HNANCIAL ACIIIMIES FOR THE YEAR ENDED 31 MARCH 2023 Y￿rt0 2023 Y•4rto 2022 Fthd• Funds Incom• and end￿MeThI3 fftm: DonBth?ns and leg￿eS Chariiable aci1vit￿8 Inter8St In￿Me 102,261 102.261 57,770 Totsl Ir￿orne 57,770 Expefidl￿r• on: Grants and tbnati¢n$ PaKI Charitabl8 Athilies 49.734 1.514 49.734 1.514 23,986 2.173 Total exFonditur¢ 26,139 Net (expendiiur•yincun¥ and net mown•rt in fuThls RKondlltlon ollund•: Total fiFnd$ brougm forward 203.246 10.2 213.448 181,815 Totsl fvnd• ¢•nl•d forw• 254

ULMPLE SCLERO&S ThALS WBORATr)N BALANCE SHEET FOR ThE YEAR ENDED 31 MARCH 2023 Net• 2023 2022 Curr•nt aM•t•: Cash al bar￿ and Fn hand 214,646 214.646 Cr•dttiTr: Anw)unts f8Nlng due within one year Net ctsrr￿t as0ts 267,426 1,2(¥Ji 213,446 Total a$$ets1888 ejjrrnnt liabdllS 284,788 213,448 264,786 Fund• Unrestrict¥d funds R•JlTkted fvnds 254.506 10,2 203,246 10,200 Tot1 fund• o•rrl•d for*anl 213 446 Th• finarKi41 $14l•mont¥ wore approved by th• btsard ¢)n Aprl 2023 and syn•d on rt$ b•haif by.. R Nlchol•s Tru•t•• The nol•s on pa9ts5 610 8 forni of tho10 finan(l•l $t•t•mwls.

MULMPLE SCLER￿5 TrWLS CCUABORATK)N NOTES TO THE FINANCIAL STATEMENTS FI￿( THE YEAR ENC)a) 31 MARCH 2023 A¢countlng poli¢1 The printspal account¢ng Foti¢ies are set bèltrw. Tho ¢ounting pol￿•e3 ho￿ been 4dcyt•J cts)sisterlty throughout the Ils Df prepariNJ th• fiTran¢lal st•¢•m finan￿￿1 stalements have been pYwaTed in occxdw￿ ith Acx>wntry aThl Rep￿[n9 ty Chafitl•s'. Stsl￿nènt RecorrYnend•d PrarAice applubl6 to chaiib"e$ preparing thr accounts in ￿rdartt wth the Financial Reporting Standard ppli¢able in lh UK 8nd Republ￿ of Irelant1 i$sued In Qthber 2019, the Financtal RaF￿rtir￿J Standwd applicable in lh• Unrted King(lom and Ropubll¢ of IreLvl IFRS 1021 and Ihe Chaiilies Act 2011. The fiNw81 slat•m•nls have been wy8red un<l¢r the historrd cost rnnv•rrtlon •nd arn prèpared on a going ts)ncem basi5. Multple Scl¢ro3is Trnls Cdlaboraion maets the dthilion of• benth errtAy under FRS 102. Golng ¢¢)no•m The finarrial itatement8 htre b8•n weparBd on a w"rwJ Co￿M basiq as the tnMt8•s bel￿0 thai no m•terfal une•rtalnties exlsl. The tru$￿5 have 9)n￿¢ser8d the lev•1 offu￿j$ h•ld and thè ¢ype(aed l•vel ol incorne and expe￿dItUre for a mittirnum 12 months frorn th• authorisalbn crfthe￿ finarti￿ stalements in aryivirs al this eonc4usion. The budytld incLsm• and expaThdilure 18 sLrfndenl with Ihe lov•1 d ruerva8 forthe chwity to ￿ able to continu& 4$ • corthm. Jud9•m•nt •nd k•y •ourM• ol •4llm•t7on un¢•tslnty The wparati¢)n of the fin•roal stst?menls r•guires marwement lo mak• Judg￿￿nts. estimat•¥ and a8SimO1'ons thal affecl th• •nounts r•ported. Th•u •irnat•s and Jud￿ents are conty"nualty revithv8d and •re based ¢)n expthiew and other factors, indtsg4n9 •xp•d#Dons of fulur¥ event$ thal arn b•li•ved to be rea%￿#ble und8r the (yrcum8tances. Incom• and •ndowm•nt• All int¢ynino r•souwrns in the of finaTWi81 artMts the ehTrty is tsntrtl￿ lo th• ￿KDm• and the amount can ba quantffied roasonabl• wrw. Th•lollOW•ing Spe￿r￿ Pol￿?$ are applied to pol￿￿J1&rcat•9ori0s of Income.. Donations and r•¢•fr4ed by way of grwiis, don#lions and gTrft$ 4r• r•coqn15•d in the p6rh)d in which Ihty ar• f•c•ivable. In¢onn fm Charflabh acbvitM&1g Incl￿ in th• wiod kn Vltwth it 59 I￿¥b￿. ExpeTrdiluro Is re￿￿$•￿ ¢)n ￿ ac¢rual8 b•s qs • I18b￿ty is irrur•d. Th• folf￿r￿j Ip• por￿￿1 •ro op￿ied to p4rticular cat•gories of •xpndltur•'. Expndltum on charftatAe aC1M￿ is costs i￿AITr8d ty the charity in th• ¢ouN ofm••ting itseh•ntablo •irnJ includlng uranl making •md r•i•ied gOv•M￿ and Jupport eojts. Th• lunds by tha Trust c•8•". Unrn8trK¢edg•Mrnlfvnds-IM Ym. lurrfls held ty Ihe chanty to t U8•d in Trth Ihts chanwe rtilects at the diaerelion of th• trust￿. R8sttst8dlunds- funds h•kl lo b8 u$od onty lor ￿irthd purposeswihin th• objtcas olth¥ charity. R•8tridon$ 4rt8• Ineom• ind •ndowm•nts Unr••trtcl•d F￿d• Yèar to 2023 Y•ar t• 2022 Oonicns •nd leg￿l•S- 0￿•1￿ Charitable ￿tivIt￿￿-Trial9 iwn¢ Interesl iwie 102.261 1tr2,281 57,770 327 327 Incomo and INd￿M•At$ in 2023 was enlirply atlrknutsbkn to unr•stit•d fuTrds.

MULTIPLE SCLEROSS TRIALS COLLABORAnON NOTES TO THE FINANQAL STATEMENTS F(Xi THE YEAR ENDED 31 MARCH 2023 ExpenrJitur• on ¢haritsbl• a￿1¥111•$ Y•arto 2023 Yearto 2022 Funds Grnnts •nd don•don•pald Imperial College Tntst Epl￿PsY Sou"ety Hollenic Pagle¢Jr iety Unrv•rsty Conego London 49,n4 49.734 22.255 1.711 49,734 $4lane$ trial f••s Trav&1 ¢tsst$ P•tient transport OfficA •xpenses Proles$ional f MS Film Accountartcy I￿114￿¢0us exp•rMes 115 700 1,440 74 1.440 74 1,200 2.173 Tot•1 •xp8ThJilur• on ¢h•itsble A¢bviliwJ 51,248 Exp•ndltur• on ch4rtlable In 2023 attr1￿bki to ￿re$￿idd Tru•t•• r•mun•rtlon Ind •xp•n•M and k•y miftag•nnt p•r•onn•l Nolrust•es or p•rsons cth)n•thd w•th them any in thetr role as Intstws frpm th• th91ty1202?. nil) And no tfUSt•o9 hav• r•ce¢v•d paymentfor yrjemonal oroth•rs•Thus provid•dto IhchAnty durlng the year {2022.' Thll. Individu•l •X￿n$•8 to1￿1￿9 nil lortravd 4nd 8ub8lsl￿￿ lo and C￿l•￿nceS(2o22'. nil) w•re reimburJed to on• truslee dudng th• yeaf. Th• trust￿9 cc*nwisod lh• kvy man•gwn•nt p•rsonnd ol th• chty1ty during tho y•m •n¢lng 31 Mareh 2023 and 31 M8r¢h 2022. T￿ charty dKI nc4 vnploy any mefflb•rs ol staff durirvJ thw years. Cr•dltorn Ymrto 2023 Ymrto 2022 AccnKd grants ptyeble 1,21JO 1,200 Unmlrict•d funds Bal4nc• at oiThr2oL2 Y••r•nd•d 31 March 2023 Balan¢• at 3110312023 Incom• Exp•ndlturn Trnn•l¢rn Genernl funds 203.246 102,588 (51.2481 254.5e8 203.246 102.588 151,248 254,586 Balance at 0111M12021 Y•ar •nd•d 31 M•reh 2022 3alane• at 31103r2022 In¢om• Exp•nditur• Tr•nsfern Gengral funds 171,615 57.7TO {26,139) 203.248 171,615 2fd,246

MULTIPLE SCLEROSIS TRIALS CWBORAIIIJN NOTES TO THE FINANCIAL STATEMENTS F<XI THE YEAR ENDED 31 MARCH 2023 RestrIct￿ fvnd8 Balance at 0110412022 Y•ar•nd•d 31 March 2023 BalJnoe at 3110312023 Incom• Expenditurn Tr4nsf•rn 10.2 10.2 10,200 Balanc• at 0110412021 Y•ar •nd•d 31 M•r¢h 2022 8alanc• at 3110312022 Incom• Exp￿dI￿v Trnn8f•rn Gfrnzyme TheraFUt 10,2 10.200 Nam• ol MbJ o•M of G•nzymo Th•rap¢ut Funds h•Ed for the Purp￿ of ming A ornnl for the purchw of an InfvslL￿ PUMP. A￿1￿% ol n•t •M•ts b4lww fund• Unr•strl¢t•d F￿d4 R••trf¢2t•d Fund• Y•4r •nd•d 31 March 2023 T¥)tl Current &ss•ls Cuffanl liabiliti'es 257,226 12.6401 10,2CQ 267,428 12,8401 254, 264.786 Ywr•nd•d 31 Marth 3022 Funds Fund• Totsl Current assats Curr•nt li•bilities 204,446 11.2CQI 10,2LKI 214,646 11,2001 203,246 TN•t••s and oth•r r•lat•d ￿rtI D•lails ol tru5t¢¢ ¢m¢Su￿￿ts and experws are disdosad in not• 4. Th•r• we no oth•r rnlated party roW.