Company number: 04397137
Charity number: 1091480
THE HOPE FOUNDATION FOR CANCER RESEARCH
(A COMPANY LIMITED BY GUARANTEE)
ANNUAL REPORT AND UNAUDITED FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31 MARCH 2025

THE HOPE FOUNDATION FOR CANCER RESEARCH
CONTENTS
Pages
Charity Reference and Administrative Details
Trustees, Annual Report
5- 10
Independent Examiner's Report
Statement of Financial Activities (including Income and Expenditure Account)
12
Balance Sheet
Statement of Cash Flows
14
Notes to the Financial Statements

THE HOPE FOUNDATION FOR CANCER RESEARCH
CHARrrY REFERENCE AND ADIVIINISTRATIVE DETAILS
FOR THE YEAR TO 31 MARCH 2025
Charity registration number
1091480
Company registration number
04397137
Patrons
Mr Martin Johnson
Mr Matt Poole
Mr Lars Tharp
Presidents
Mr Rick Moore
Trustees
Mr James Greenlee5 (Chair from April 2025)
Mr Robert Marsh (Vice-chair from April 2025)
Professor Nigel Brunskill
Mrs Elizabeth Coates (appointed l July 2025)
Mr Duncan Green
Mr lan Guyler
Professor lan Lauder
Ms Kishani Navin (appointed 2) July 2024)
Co-optee
Professor Andreas Gescher
Chief Executive Officer
Mr Nig¢1 Rose
oirice & Volunteer Manager
Mrs Barbara North
Corparate & Community
Partnerships Managers
MTS Tracey Hallam (appointed January 2025)
Mr Martin Robinson
Comms & Marketing Manager
Mr John Nellis
Registered office
Knighton Lodg¢
208 Knighton Road
Leicester
Independent Examiner
UHY Hacker Young
14 Park Row
Nottingham
NGI 6GR

THE HOPE FOUNDATION FOR CANCER RESEARCH
CHARITY REFERENCE AND ADMtNISTRATIVE DETAILS (CONTINUED)
FOR THE YEAR TO 31 MARCH 2025
Bankers
HSBC Bank
Clock Tower Branch
2-6 Gallowtree Gate
Leicester
LEI IDA
Investment managers
Brewin Dolphin Limited
I Sl Floor Waterfront House
Wat¢rfront Plaza
35 Station Street
Nottingham
NG2 3DQ

THE HOPE FOUNDATION FOR CANCER RESEARCH
TRUSTEES, ANNUAL REPORT (INCLUDING DIRECTORS, REPORT)
FOR THE YEAR TO 31 MARCH 2025
The Trustees present their report and the ind¢pendently examined financial statements of the charity for the
year ¢nded ) l March 2025. Th¢ trustees have adopted th¢ provisions of the Statement of Recommended
Practice (SORP) "Accounting and Reporting by Charities" (FRS 102) in preparing the annual report and
financial statements of th¢ charity.
The financial statements have been prep8r¢d in accordance with the accounting policies s¢t out in notes to
the accounts and coinply with the charity's governing document, the Charities Act 2011 and Accounting
and Reporting by Charities- Staternent of Recommended Practice applicable to charities preparing their
accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ireland
published in October 2019.
Trustees of the charity
The directors of th¢ charitable company are its trustees for the purpos¢5 of charity law. The trustees who
have served during the y¢ar and since the year end wer¢ as follows:
Mr James Greenlees
Professor lan Lauder
Mr Rick Moore
Mr Duncan Green
Professor Nigel Brunskill
Mr Robert Marsh
Mr lan Guyl¢r
Ms Kishani Navin
MTS Elizabeth Coates
(Resigned l July 2025)
(Appointed 23 July 2024)
(Appointed l July 2025)
Estsblishment and Objectives
The Hope Foundation for Cancer Research in Leicestershire and Rutland, ' Hope Against Cancer, ("the
Charity") was registered as a charity and incoryK)rated as a company limited by guarantee in MaTch 2002.
It was fornied in Order to provide funding for cancer research projects in Leicestershire and Rutland. The
annual report ￿CordS a further year of achievement of the objects of the Charity. Its objects are:
the promotion and undertaking of research into the causes, propety, biology. detection, prevention
and treatment of cancer and to publish and disseminate the results of such research.
the r¢li¢f of pain and suffering of cancer patients through the implementation and improvement of
medical andlor surgical procedures through the study of cancer and all its ramifications be they
clinical, scientific, psychological, social or economic. and
the ¢ncouragement and advancement of innovations for detection and treatment of cancer.
Structure, Governance and Management
The Charity is governed by it5 Memorandum and Articles of Association dated 18 March 2002 (as amended
by a special resolution in 2005 and 2014).
Membership is limited to 14 members who are its trustees and directors ("the trustees"). Trustees, including
Chair and Vic¢-Chair are appointed on three-year ternis of service, with potential re-election depending on
the governance needs of the Charity.

THE HOPE FOUNDATION FOR CANCER RESEARCH
TRUSTEES, ANNUAL REPORT (INCLUDING DIRECTORS, REPORT)
FOR THE YEAR TO 31 IVIARCH 2025
There is an induction programme for trustees which includes provision of detailed infomiation and a
description of roles and responsibilities, register of interests, procedures for meetings, code of conduct,
stt7tegic plan and copies of previous r¢ports and minutes.
The Board meets quarterly and makes decisions on research funding with the assistance of the Research
Advisory Panel {"RAP"). experts in academic and clinical research, who are called upon and convened as
and when necessary to advise the wider board on informing the Charity's research investment decisions.
There is regular attendance and reporting from lead professionals in th¢ Leicester Cancer Research Centre
and Hope Cancer Trials Centre.
The day to day running of the Charity is delegated to a Chi¢f Executive Officer who manages a small staff
team and volunteers.
Aehievements and Performance
Researeh Grants and other funding
In 2024 The Leicester Cancer Research Centre had identified th¢ following priority areas for consideration
of funding within the 202412025 period, aligning with and supporting its Bio-medical Research Council
'BRC") and Experimental Cancer Medicine Centre ("ECMC"). The following priority areas were
identified..
HOPE Research Nurses - £1 00,000
This is an ongoing salary commitment to support two 'HOPE" nurses within the HOPE Cancer Trials
Centre, Leicester Royal Infirniary. Contribution to funding of th¢5e two nurses helped to support priority
areas of growth within the cancer portfolio which align with our Centre strategy. This model has been
highly successful with Leicester recruiting a high number to multiple trials. Continued funding remained
essential to the delivery of The Cenlre's expanding portfolio. We are proud to support a diverse portfolio
of over 200 clinical trials that reflects the needs of our local population
Clinical MD/PhD Studentship - £1 00,000 - Funds were allocated in three areas..
Provid¢ partial salary sup]x)rt for a clinical research fellow, Dr Shradha Bhagani (from August
2024 onwards for 2 years), to complete an MDIPhD;
2. To purchase a new -80 C freezer that will support key work within the Leicester ECMC. and
To support pump priming of ) projects within the Leicester Canc¢r Research C¢ntr¢ aligned with
th¢ir strategic objectives.
Risk Management
A risk management programme is in place. The Chair annually consults trustees individually to assist in
identifying risks associat¢d with the charity's a¢tiviti¢s so as to incorporate appropriate actions into
operational plans. A ski115 audit is used in the appointment of new trustees to ensure that skills required for
continuing strategic leadership are available. Induction processes for trustees and volunteers are thorough.
All are aware of the responsibilities associated with their role.
Financial procedures are in place to protect cash and investments and risk of theft or fraud is thought to be
low. The maintaining of unreslricted reserves al an agreed level will provide sufficient resource in the event

THE HOPE FOUNDATION FOR CANCER RESEARCH
TRUSTEES, ANNUAL REPORT UNCLUDING DIRECTORS, REPORT)
FOR THE YEAR TO 31 MARCH 2025
of loss of voluntary income. An 'investment sub-cominittee, has been fonlled which includes the Chief
Executive and two trustees with thorough investment and financial planning skills and experience to
monitor and review investments and make recommendations to the full Board.
Volunteer training programmes are on-going and volunteer recruitment, retention and dev¢lopment policies
are regularly reviewed.
Regular contact is maintained with researchers to ensure that the funds are spent in accordance with the
conditions attached to each grant made. Grant application processes and reporting and monitoring
arrangements have b¢¢n reviewed to ensure fitness for the major investments into the centre of excellence
partnership for the medium terni (3-5 years).
IT backup and protection systems aT¢ in place and maintained. A database and cloud-based server to
optimise customer relalionship management and modernise secure data storage is operating. Property tenure
has been secured with our partners at the University of Leicester and is reviewed annually.
Impaet
The Charity's strategy is to work in partnership with local universities and hospitals to ensure that
Leic¢st¢rshire remains a centre of excellence for cancer research and treatment to achieve the greatest
impact in the local and national fight against cancer. With public support and the support of public sector
and charity partners, we have helped to achieve the following..
HOPE ha5 enabled the Centre to continue to recruit strongly to open trials, with a number exceeding their
Tecruitment targets. It has been exciting to see some trials move onto the next stage of development due to
early activity.
Some of the HOPE-funded PhD students within the LCRC have also opened th¢ir studies (all ethically
approved by UOL sponsors) which are part of their PhD project and the Hope team have helped to support
through assisting with taking blood and identification of patients whom may be able to help with surveys
and questionnaires.
New research collaborations with Cambridg¢ and Birmingham Experimental Cancer Medicine Centres
("ECMCs") ar¢ und¢nvay to strengthen reach and ability to deliver.
The Centre staff continue to receive wonderful feedback from patients and family members about the caTe
and facilities that are provided.
The nursing team have also helped with recruitment to the Canccr Biobank, supporting academic studies at
the Univ¢rsity of Leicester. They have I￿en identifying patTents not only for clinical trials but also patients
that May k suitable to be considered for the Biobank. This has led to successful recruitment of patients
with a diagnosis of head and neck cancers.
The new -80 C freezer arrived as planned and is already 5UPPOrting a number of key ECMC sample
collections. Having this freezer in place enables ability to support key activitie5 Wlthin the centre. From a
sustainability point of view thTs is a much more en¢rgy-effici¢nt freezer and supports our commitment to
reducing our environmental impact.

THE HOPE FOUNDATION FOR CANCER RESEARCH
TRUSTEES, ANNUAL REPORT (INCLUDING DIRECTORS, REPORT)
FOR THE YEAR TO 31 MARCH 2025
Financial Review
During the year th¢ Charity has received income of £627,669 (2024.. £428,845).
The Charity spent a total of £812,674 {2024'. £524,770). including grants to the value of £517,215 (2024:
£130,000) were funded.
At the year end liquid funds of £1.147.594 (2024.. £1,342,796) were held.
Brewin Dolphin Limited has acted as discretionary investment managers to take care of the shar¢ portfolio
valued at the year end at £46J,258 (2024: £46i,65)) in accordance with the charity's Investment Policy.
Public Benefit
The trust¢¢s have monitOTed the way in which Charity funds are expended and consider that this is in line
with the objects of the charity and for the benefit of the public. The Cl)arity's main objective is to fund
cancer research that saves lives or improves the quality of life through earlier diagnosis. pr¢v¢ntion or better
tr¢atm¢nt of cancer. This brings significant public health benefits to local communities.
The directors consider that they hav¢ cornplied with their duties under the Charities Act 2011 to have due
r¢gard to public benefit guidance published by the Charities Commission.
Fundraising Regulator
The Charity participates in the Fundraising Regulator's voluntary regulation scheme. The trustees consider
the Charity has complied with The Code of Fundraising Practice as outlined on the Fundraising Regulator's
w¢bsite at www.fundrai5ingregulator.org.uk/code.
Investment Policy
Sco
This policy applies to all cash reserves and investmcnts held by the foundation. including funds placed in
savings or deposit accounts, which are considered investments as per Charity Commission guidance.
Ob'ectives
Preservation of Capital: Protect the foundation's Cash reserves to ensure funds are available for
operational and programmatic needs.
Liquidity: Maintain sufficient liquidity to meet short-terni operational requirements and
unforeseen circumstances.
Income Generation: M&ximize interest income on cash reserves within low-risk paTarneters to
support the charity's activities.
Risk Management-. Diversify deposits acTOSS multiple institutions to maximize Financial
Services Compensation Scheme ("FSCS") protection and minimize risk.

THE HOPE FOUNDATION FOR CANCER RESEARCH
TRUSTEES, ANNUAL REPORT {INCLUDING DIRECTORS, REPORT)
FOR THE YEAR TO 31 MARCH 2025
Guidelines:
Funds will be placed in FCA-authorized UK banks or building societies using a mix of staggered 3- or 6-
month fixed-tenn deposits and 30- OT 90-day notice accounts to balance interest income with short-tern]
accessibility. We may place deposits exceedingthe £85,000 FSCS limit with well-funded, stable banks with
strong credit ratings, diversifying across institutions to manage risk and prioritizing low-risk, FSCS-
protected accounts where possible. Ethical considerations will guide bank selection, and a portion of
reserves will remain in instant access accounts to meet immediate needs.
Reserves Policy
The basic requirement of the reserves policy is to maintain free res¢rves, in unrestricted general funds, at a
level which ensures that the charity will be able to meet at least six months committed expenditure,
including ¢v¢nt costs as well as funding grants which will arise in the coming year.
The Trustees are satisfied that the unrestricted and undesignated general funds at the year-¢nd of £1,147,594
are appropriat¢. However it remains vital that we continue to raise funds to support cancer research.
Plans for the future
The Trustees will continue to supwrt the Hop¢ Cancer Trials Centre which is an internationally-r¢nowned
and recognised research environment and will remain central to helping ensure continued success of all the
Centre's national grant bids, leveraging income from national institutions and funding bodies, to be spent
locally and Tegionally on the research efforts here.
HOPE will also continue to respond to planned and timed annual funding requests that support the strategy
of the Leicester Cancer Research Centre {"LCRC"), including some developm¢nt projects, funding vital
medical research equipment that hekps speed up progress of research.
We will also support a long-tem NHS plan on delivering a new cancer service5 centre at a site to be
determined.
Aeknowledgements
The Board acknowledges and thanks all its volunteers, generous corporate sponsors and individual
supporters and donors. It thanks the University of Leicester for providing the Charity's office
accommodation.
Trustees, responsibilities
The trustees (who are also directors of The Hope Foundation for Cancer Research for the purposes of
company law) are r¢sponsibl¢ for preparing the Trustees, Annual Report and the financial statements in
accordance with applicable law and United Kingdom Accounting Standards (United Kingdom Generally
Accepted Accounting Practice).
Company law requires the trustees to prepare financial stat¢ments for each financial year, which give a true
and fair view of the state of affairs of the charitable company and of the incorning resources and application
of resources, including the income and expenditure, of the ¢haritabl¢ company for that period. In Preparing
these financial statements, the trustees are required to-

THE HOPE FOUNDATION FOR CANCER RESEARCH
TRUSTEES, ANNUAL REPORT (INCLUDING DIRECTORS. REPORT)
FOR THE YEAR TO 31 MARCH 2025
elect suitable accounting policies and then apply them consi5tently'
observe the methods and principles in the Charities SORP 2019 (FRS 102)-
make j udgments and estimates that are reasonable and Prudent.
state whether applicable UK Accounting Standards have been followed, subject to any material
departures disclosed and explained in the financial statements. and
prepare the financial statements on the going concern basis unless it is inappropriate to Presume
that the charitable company will continue in operation.
The trust¢¢s are responsible for keeping adequate accounting records that disclose with reasonable accuracy
at any time the financial position of the charitable company and enable them to ensure that the financial
statements comply with the Companies Act 2006. They are also responsible for safeguarding the assets of
the charitable company and hence for taking reasonable steps for the prevention and detection of fraud and
other irregularities.
In so far as the trustees are aware:
there is no relevant audit infonnation of whicli the charitable company's auditor is unaware. and
the trustees have taken all steps that they ought to have taken to make themselves aware of any
relevant audit infomlation and to establish that the auditor is aware of that infom]ation.
The trustees are responsible for the maintenance and integrity of the corporate and financial inforniation
in¢lud¢d on the charitable coinpany's webslte. Legislation in the United Kingdom governing th¢
preparation and dissemination of financial statements may differ from legislation in other jurisdictions.
Diselosure of information to the independent examiners
We, the directors of the company who held office at the date of approval of these Financial Stat¢m¢nts as
set out above each confirm. so far as we are aware, that:
there is no relevant audit infonnation of which the company's independent examiners are unaware. and
we have taken all the steps that we ought to have taken as directors in order to make ourselves aware
of any relevant infonmaiion and to establish that the company's independent examiners are aware of
that infom]ation.
On behalf of the board
Mr James Gr¢enlees
Chair of the Board of Trustees
Date:
Company Registration number: 04397137
Charity number: 1091480
10

UHY
41HV HKk•rY•uno LLP
14 Park f+(w
Notlingham N616G
THE HOPE FOUNDATION FOR CANCER RESEARCH
INDEPENDENT EXAMINER'S REPORT FOR THE YEAR TO 31 I￿ARCH 2025
I report on the accounts of the company for the year ended 31 March 2025 which are set out on pages 12 to
23.
Respective responsibilities of trustees and examiner
As the charity's trustees of tlie company {and also its directors for the purposes of company law) you are
responsible for the preparation of the accounts in accordanc¢ with the requirements of the Companies Act
2006 ('the 2006 Act,).
Having satisfied myself that th¢ accounts of the company are not required to be audited under Part 16 of
the 2006 Acl and are eligible for independent examination, I report in reS￿¢t of my examination of your
charity's accounts as carried out under section 145 of the Charities Act 2011 (the '201 l Act,). In carrying
out my examination I have followed the Directions given by the Charity Coininission under section
145{5)(b) of the 201 l Act.
Independent examiner's report
Since the Company's gross income exceeded £250,000 your examiner must b¢ a mernber of a body listed
in section 145 of the 2011 Act. l confirni that l am qualified to undertake the examination ￿caUSe l am a
member of ICAEW, which is one of the listed bodies.
I have completed my examination. I confirm that no material matters hav¢ come to my attention in
connection with the examination giving me cause to believe:
( l ) accounting records were not kept in r¢5P¢Ct of the company as requTred by section J86 of the 2006
(2) th¢ accounts do not accord with those accounting records. or
(3) the acwunts do not comply with the accounting r¢quir¢m¢nts of section i96 of the 2006 Ad othcr
than any requirement that the accounts give a 'true and fair, view which is not a matter considered as
part of an independent examination. or
(4) the accounts hav¢ not been prepared in accordance with th¢ m¢thods and principles of the Statement
of Recommended practice for accounting and reporting by charities applicable to charities preparing
their accounts in accordance with the Financial Reporting Standard applicable in the UK and R¢publi¢
of Ireland (FRS 102).
I have no concerns and have come across no other matters in connection with the examination to which
attention should be drawn in this report in order to enable a proper understanding of the accounts to be
reached.
Chris McKain FCA
UHY Hacker Young
Chartered Accountants
Date:
li. fvJvrf£M64&. 2v2S

THE HOPE FOUNDATION FOR CANCER RESEARCH
STATEMENT OF FINANCIAL ACTIVITIES (INCLUDING INCOME AIYD
EXPENDITURE ACCOUNT)
FOR THE YEAR TO 31 MARCH 2025
2025
Unrestricted
Funds
2024
Unrestricted
Funds
Note
Income from:
Voluntary income
Investment income
58i,251
44,418
J91,J04
37,541
Total income and endowments
627,669
428.845
Expenditure on:
Generating funds
Charitable activities
295,459
517,215
J94,770
l)O,000
Total expenditure
812,674
524,770
Net expenditure
(185.005)
(95,925)
Net (Ioss¢5) I gains on investments
(10,197)
19,671
Net movement in funds
15
(195,202)
(76,254)
Reconciliation of funds:
Total fund5 brought forward
15
1,)42,796
1,419,050
Total funds carried forward
15
.147 594
1,342,796
All income and expenditure derive from continuing activities.
The statement of financial activities includes all gains and losses recognised during the year.
The note5 on page5 15 to 23 form part of these financial staternent5.
12

THE HOPE FOUNDATION FOR CANCER RESEARCH
BALANCE SHEET
FOR THE YEAR TO 31 MARCH 2025
2025
2024
Iyote
Fixed assets
Tangible assets
Investments
io
5,411
46J,258
463,653
468,669
46J.65J
Current assets
Debto
Cash at bank and in hand
12
8.995
I,J57,936
12,795
1,331,473
,366,9i I
I,J44,268
Creditors: amounts falling due within
one year
13
(688,006)
(465,125)
Net current assets
678.925
879,14)
Net assets
,147.594
I,J42,796
Charity Funds
Unr¢stri¢ted funds
15
,147,594
1,)42,796
Total charity funds
15
.147,594
1,342,796
For the financial year ended J l March 2025 th¢ company was entitled to exemption und¢r section 477 of
the Companies Act 2006 relating to small companies. No members have required the company to obtain
an audit of its accounts for the year ended J l March 2025 in accordance with Section 476 of the
Companies Act 2006. The directors acknowledge their responsibility for complying with the requirements
of the Act wlth respect to accounting records and for the preparation of accounts.
These accounts have been prepared in accordance with the provisions applicable to comwanies subject to
the small coinpanies, Te
Ine. The financial slatcm¢nts were approved and authorised for issu¢ by the
Boardon.....
Signed on behalf of the board of trustees by:
Mr James Greenlees
Chair of the Board of Trustees
Company Registration number: 04397137
Charity number: 1091480
The notes on pag¢s 15 to 2J fonn part of these financial statements.
13

THE HOPE FOUNDATION FOR CANCER RESEARCH
STATEMENT OF CASH FLOWS
FOR THE YEAR TO 31 MARCH 2025
2025
2024
Note
Cash outflow from operating activities
16
(2,179)
(172,587)
Net cash oufflow from operating activities
(2,179)
(172,587)
Cash flow from investing activities
Purchase of tangible fixed assets
Purchase of investinents
Proceeds from sale of investments
Interest received
Dividends received
(5.974)
(101,807)
92,005
31,356
13,062
(96,8J6)
99,286
27,463
10,078
Net cash flow from investing activities
28,642
Net increase l (decrease) in cash and cash equivalents
(1)2,596)
Cash and cash equivalents at l April
I,JJ1,47J
1,464,069
Cash and cash equivalents at 31 March
l.J57,9)6
l ))1.47i
Cash and cash equivalents consists of:
Current account
Money market deposits
Broker's accounL
Deposit account
Charity bonds
13,169
8J4,577
7,884
287,767
214,539
E6,445
815,901
14,172
279,284
205,671
Cash at bank and in hand at 31 March
l.J57,936
,JJl,473
The notes on page5 15 to 23 form part of these financial statements.
14

THE HOPE FOUNDATION FOR CANCER RESEARCH
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR TO 31 MARCH 2025
Summary of significant accounting polieies
(a) General information and basis of preparation
The Hope Foundation for Cancer Research is a company limited by guarantee registered in England
& Wales and a registered charity in England. The address of the registered office is given in the
charity reference and administrativ¢ details on page 3 of th¢se financial statements. The nature of the
charity's operations and principal activities are outlined on page 5.
The charity constitutes a public benefit entity as defined by FRS 102. The financial statements have
been prepared in accordance with Accounting and Reporting by Charities.. Statement of
Recomm¢nded Practice applicable to charities preparing their accounts in accordance with the
Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS 102) October 2019,
the Financial Reporting Standard applicable in the United Kingdom and Republic of Ireland (FRS
102), the Charities Act 201 I, the Companies Act 2006 and UK Generally AWept￿ Practice.
The financial statements are prepared on a going concern b&8is under the historical cost convention,
modified to include certain items at fair value. The financial statements are presented tn sterling
which is the functional currency of the charity and rounded to the nearest £.
Th¢ significant accounting policies applied in the preparation of thes¢ financial statements are set out
below. Th¢s¢ policies have been consistently applied to all years presented unless otherwise stated.
(b) Fund$
Unrestricted funds are available for use at th¢ discretion of the trustees in furth¢ran¢e of the general
objectives of th¢ charity and which have not be¢n d¢signated for other purposes.
Designated funds comprise unrestricted funds that have been set &side by the trustees for particular
purposes. The aim and usc of each designated fund is set out in the notes to the financial statements.
Restricted funds are funds which are to be used in accordance with specific restrictions imposed by
donors or which have been raised by the charity for particular purpose5. No such funds are currently
held.
(e) Ineome recognition
All incoming resources are included in the Stat¢m¢nt of Financial Activities (SOFA) wh¢n the charity
is legally entitled to the income after any perfomance conditions have been met, the amount can b¢
measured reliably and it is probabl¢ that the income will be received.
For donations to be recognised the charity will have been notified of the amounts and th¢ settlement
date in writing. If there are conditions attached to the donation and this requires a level of perfomiance
before entitlement can be obtained then income is deferred until those conditions are fully met or the
fulfilment of those conditions is within the control of th¢ charity and it is probable that they will be
fulfilled.

THE HOPE FOUNDATION FOR CANCER RESEARCH
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR TO 31 MARCH 2025
For legacies, entitlement is the earlier of the charity being notified of an impending distribution or the
legacy being received. At this point income is recognised. On occasion legacies will be notified to the
charity however it is not possible to measure the amount expected to be distributed. On these
occasions. the legacy is treated as a contingent asset and disclosed.
Income from trdding activities includes income earned from fundraising events and trading activtties
to raise funds for the charity- Income is received in exchange for supplying goods and services in
order to raise funds and is recognised when entitlement has occurred.
Investment income is earned through holding assets for investment purposes such as shares. It
includes dividends and interest. Interest income is recognised using the effective interest method and
dividend income is recognised as the charity's right lo receive payment is established.
(d) Gifts in kind
The charity benefits from many hours given freely by trustees, patron5 and other volunteers. The
charity is extremely grateful for all these gifts in kind. It is extremely difficult to place a value on the
time gifted and accordingly, this not included within the Statement of Financial Activities.
(e) Expenditure recognition
All expenditure is accounted for on an accruals basis and has been classified under headings that
aggregate all costs related to the category. Expenditure 15 recognised where there is a legal or
constructive obligation to make payments to third parties. It is cat¢goris¢d under th¢ following
h¢adings:
Expenditure on generating funds includes costs incurred attracting voluntary income. and
Expenditure on charltable activities includes grants and funding given in accordance with the
Charity's aims and objectives.
Grants payabl¢ to third parties aTe within the charitable objectives. Where unconditional grants ar¢
offered, this is accrued as soon as the rccipi¢nt is notified ofthe grant, as this gives rise to a reasonable
¢xpectation that the recipient will receive the grants. Where grants ar¢ conditional relating to
performance then the grant is only accrued when any unfulfilled conditions are outside of the control
of the charity.
(D Tangible fixed assets
Tangible fixed assets arc stat¢d at cost less accumulated depreciation. Cost includes cost5 directly
attributable to making the asset capable of operating as intended.
Depreciation is provided on all tangible fixed assets, at rates calculated to write off the cost, les5
estimated residual value, of each asset on a systematic basis over its expected useful life as follows:
Fixtures and fittings
Computer equipment
Molor v¢hicle
200/0 straight line
J3 % straight line
250/0 slraight line
All assets with a value less than £1,250 are written off in the year in which they are acquired.
16

THE HOPE FOUNDATION FOR CANCER RESEARCH
NOTES TO THE FtNANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR TO 31 IVIARCH 2025
(g) Investments
Inv¢stments are recognised initially at fair value which is norrnally th¢ transaction price excluding
transaction costs. Subsequently, they are measured at fair value with changes recognised in 'net gains
/ (losses) on investinents, in the SOFA if the shares are publicly traded or their fair value can otheNiise
be m¢asured reliably.
(h) Cash and cash equivalents
Cash and cash equivalent5 are basic financial assets and include cash in hand, deposits held at call
with banks, other short-tenn liquid investments with original maturities of three months or less.
(i) Taxation
The charity is an exempt charity within the meaning of schedul¢ J of the Charities Act 201 l and is
considered to pass the tests set out in Paragraph I Schedule 6 Finance Act 201 O and therefore it meets
the definition of a charitable company for UK corporation tax purposes.
Voluntary income
2025
2024
General donations
Events
In memoriam
Regular giving
University of Leicester
Books
Tax refund
J87,896
1)9,i54
8,522
6,964
7.854
1,665
251.987
82,072
6,564
8,472
896
29,920
583.251
)91.i04
All voluntary income received in 2024 and 2025 is unrestricted.
Investment income
2025
2024
Bank interest
Share divid¢nds
10,078
44,418
i7,541
All investment income received in 2024 and 2025 is unrestricted.
17

THE HOPE FOUNDATION FOR CANCER RESEARCH
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR TO 31 MARCH 2025
Cost of generating funds
2025
2024
Note
General costs
Events
Capital development Costs
249,559
39,588
6,i12
255,884
57,114
81.772
295,459
394.770
Analysis of general costs
2025
2024
Staff costs
Staff and volunteer training
Staff and volunteer recruitment
Equipment
Utilities
Postage and stationery
T¢l¢phone and internet charges
Insurance
Marketing
Travel expenses
Bank charges
Subscriptions
Depreciation
Miscellaneous
Administrative costs
Legal and professional fees
178,142
1,287
1,661
174,012
,263
1,951
14,275
4,022
4,581
1,659
1,846
4,918
1.614
1,884
21.114
3,882
2,770
90)
4,139
4,002
8,165
1,200
249.559
255,884
Essentially all costs incurred relatc to fundraising for the charity and are unr¢stricted for both 2024
and 2025. Within the costs for the year a total of £6,J12 (2024- £81,772) was in relation to the
designated fund for a capital projcct.
Charitable activities
2025
2024
Note
Grants awarded
517,215
130,000
All grants awarded for 2024 and 2025 are unrestricted.

THE HOPE FOUNDATION FOR CANCER RESEARCH
NOTES TO THE FINANCIAL STATEMENTS (CONTtNUED)
FOR THE YEAR TO 31 IIIARCH 2025
Analysis of grants
Period of
Award
202512026
202412025
2025
2024
CTF Nurse 2025126
Salary support for Dr Shradha Bhagani-2024125
Salary support for Dr Niki Patil and Dr Shradha
Bhagani-2025126
Aseptic Suite
CTF Nurse 2024125
Precision Cancer Theme Support
LCRC- 2021122
112,752
100,000
202512026
117,496
iOO,000
202412025
20221202J
202112022
i 00,000
( i 00,000)
{ l ).O)J)
iO,000
517,215
liO,000
Amounts awarded to date but still due for paym¢nt totalled..
2025
2024
Due
within
one
year Total due
Due
within
one year Totsl due
Salary support for Dr Niki Patil and Dr
Shradha Bhagani - 2025126
Salary support for Dr Niki Patil and Dr
Shradha Bhagani - 2024125
Aseptic Suite
Dr Lynn Furber (Breast Cancer)
CTU Nurse 2022123
CTU Nurse 202J124
CTU Nurse 2024125
CTU Nurse 2025126
LCRC- 2021122
Precision Cancer Theme Support
Clinical PhD Fellowships
117,496
117,496
100,000
JOO,000
15,680
loo,000
300,000
15,680
15,680
1,005
i 00.000
i 00.000
15,680
1,005
loo.000
loo,000
112,752
12.189
112,752
12,189
29,464
i 00,000
100.000
29,464
loo,000
loo,000
658,117
658,117
446,149
446,149
Trustees, and key management personnel remuneration and expenses
The trustees neither received nor waived any remuneration during the year (2024: £Nil).
The trustees did not have any expenses reimbursed during the year (2024: £Nil).
The total amount of employee benefits received by key management personnel is £62,694 (2024..
£62,694). The charity considers its key management personnel to be the Chief Executive Officer.
19

THE HOPE FOUNDATION FOR CANCER RESEARCH
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR TO 31 MARCH 2025
Staff costs and employee benefits
The charity relies on the services of 5 (2024.. 5) employees.
Th¢ total cost of these individuals in the year was £178,142 (2024.. £174,012).
One employee received total employee benefits (excluding employer pension costs) within the range
£60,000 to £69,999 (2024.. one).
10 Tangible fixed assets
Fixtures and
rittings
Motor
Vehicle
Computer
equipment
Total
Cost or valuation:
At l April 2024
5,448
10,251
Additions
3,500
2.474
5,974
Disposals
(1,472)
(1,472)
At J l March 2025
6,450
Depreciation:
At l April 2024
5,448
10,251
Depreciation
220
343
563
Eliminated on
disposal
(1,472)
(1,472)
At 31 March 2025
220
4,319
9,342
Net book value:
At J l March 2024
3.280
5,411
At J l March 2025
-20-

THE HOPE FOUNDATION FOR CANCER RESEARCH
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR TO 31 MARCH 2025
I l Fixed asset investments
2025
2024
Market value at l April
Acquisitions at cost
Sales proceeds from disposals
Net (losses) I gains on revaluation in the year
46J.65J
101,807
(92,005)
(10,197)
446,4J2
(99,286)
19.671
Market value at 31 March
463,258
46J.65J
Historical wst as at 31 March
450,470
4)5.616
Investm¢nts at fair value compromise:
2025
2024
Listed investments in the UK
Listed investments outside the UK
165,857
297,401
168,467
295,186
46J,258
46i,65J
Listed investments held outside the UK include shares held in Guernsey which th¢ trustces consider
to be an inactive market. The shares have been valued at the traded value nearest to the year end as,
in the opinion of the trustees, this fairly reflects the value of shares at 31 March 2025. All oth¢r
investments have been valued at the market value at J l March 2025.
12 Debtors
2025
2024
Prepayments and accrued income
8,995
12,795
21

THE HOPE FOUNDATION FOR CANCER RESEARCH
NOTES TO THE FINIINCIAL STATEMENTS (CONTINUED)
FOR THE YEAR TO 31 MARCH 2025
13 Creditors: amounts falling due within one year
2025
2024
Notes
Other tax and social security
Accruals for grants payable
Accruals
Deferred income
658.117
4,573
20,995
446,149
4,047
11.561
14
688,006
465.125
Included within ￿¢rualS are unpaid pension contributions of £J27 (2024: £231).
14 Deferred income
2025
2024
At l April
Additions during the year
Amounts released to income
11,561
20.995
(11,561)
11.598
11,561
(11,598)
At i l March
20,995
11,561
Incom¢ has b¢¢n defe￿ed as it relates to events held after the year end.
15 Fund reconciliation
2025
Balance
at l April Income
2024
Loss on
Balanee at
Expenditure investments 31 March
2025
Undesignated
Designated
860.960
481,8J6
627,669
(506,J62)
(306,312)
(10,197)
972.070
175.524
Unrestricted
I,J42,796
627,669
(812,674)
(10,197)
1,147,594
£53.039 of th¢ 2025 unrestricted funds arc designated for a project to obtain additional don0￿.
£122.485 of the 2025 unrestricted funds are designated for a capital appeals fund for a major and
ambitious expansion project at the Hope Clinical Trials Facility at Leicester Royal Infinnary.
22-

THE HOPE FOUNDATION FOR CANCER RESEARCH
NOTES TO THE FINANCIAL sTATE1V￿NTs (CONTINUED)
FOR THE YEAR TO 31 MARCH 2025
2024
Balance
at l April Income
2023
Gains on
Balance at
Expenditure investments 31 March
2024
Undesignat¢d
Designated
855,442
563,608
428,845
(442,998)
(81,772)
19,671
860,960
481,8i6
Unrestricted
1,419,050
428,845
(524,770)
19,671
1,342,796
£59,J51 of the 2024 unrestricted funds are designated for a project to obtain additional donors.
£422,485 of the 2024 unrestricted funds are designated for a capital appeals fund for a major and
ambitious expansion project at the Hope Clinical Trials Facility at L¢icester Royal Infirmary.
16 Reeonciliation of net expenditure to net cash flow from operating activities
2025
2024
Deficit for the year
{195,202)
(76,254)
Depreciation
Interest received
Dividends received
Fair valuation movement of investments
Decreasel(incr¢ase) in debtors
Increasel(decrease) in creditors due within one year
563
(31,J56)
( l J,062)
10.197
3,800
222,881
(27,46J)
(10,078)
(19.671)
(2,099)
(J7,022)
Cash outflow from operating activities
(2.179)
(172.587)
17 Related party transactions
There are no Telat¢d party transactions during the period (2024.. £Nil).
23