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2025-07-31-accounts

Charity registration number 1043280

Company registration number 03005230 (England and Wales)

M. S. RESEARCH TREATMENT AND EDUCATION LIMITED ANNUAL REPORT AND UNAUDITED FINANCIAL STATEMENTS FOR THE PERIOD ENDED 31 JULY 2025

M. S. RESEARCH TREATMENT AND EDUCATION LIMITED

LEGAL AND ADMINISTRATIVE INFORMATION

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Trustees B T Clacy C Singleton (Appointed 4 November 2024) The Honourable S L Joiner (Appointed 4 November 2024)

Secretary

L Taylor

Charity number 1043280

Company number 03005230

Registered office

Spirella Building Bridge Road Letchworth Hertfordshire United Kingdom SG6 4ET

Independent examiner

Azets Audit Services Westpoint Lynch Wood Peterborough Cambridgeshire United Kingdom PE2 6FZ

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M. S. RESEARCH TREATMENT AND EDUCATION LIMITED

CONTENTS

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Page
Trustees’ report 1-2
Independent examiner's report 3
Statement of financial activities 4
Balance sheet 5
Notes to the financial statements 6-13
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M. S. RESEARCH TREATMENT AND EDUCATION LIMITED TRUSTEES' REPORT (INCLUDING DIRECTORS' REPORT) FOR THE PERIOD ENDED 31 JULY 2025 I

The trustees present their annual report and financial statements for the period ended 31 July 2025.

The financial statements have been prepared in accordance with the accounting policies set out in note 1 to the financial statements and comply with the charity's Articles and Memorandum, the Companies Act 2006 and “Accounting and Reporting by Charities: Statement of Recommended Practice applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of ireland (FRS 402)" (effective 1 January 2019).

Objectives and activities The charity's objectives were changed during the year ahead of a merger with the Multiple Sclerosis Trust that was enacted on 4 November 2024. Its objectives are to advance the education of persons by co-operating with the medical profession to encourage scientific research into the causes of and cure of multiple sclerosis (MS) and to aid and ameliorate the conditions of those suffering from it; and promote and fund research that can be expected to further the understanding of MS and lead to more effective clinical treatment to develop or test therapeutic equipment and investigate methods of social management of the disease and to publish the useful results thereof. Prior to the merger with the Multiple Sclerosis Trust, the charity primarily carried out these objectives by provision of grant funding for research projects and programmes that aim to advance the treatment and management of MS. The charity also supported further development of some successful treatment strategies beyond the research phase, providing “real world” evidence to support the aims of promoting new treatment modalities and better treatment strategies for people who have MS. The trustees have paid due regard to guidance on public benefit issued by the Charity Commission in deciding what activities the charity should undertake.

Achievements and performance Most of the activity undertaken during the year prepared the charity for the merger with the Multiple Sclerosis Trust. This notwithstanding, in August 2024, the charity awarded a three-year funding agreement with Dr Gavin Brittain of Sheffield Teaching Hospitals NHS Foundation Trust to explore real-world mobility in Progressive MS using wearable technology. Ongoing review of the progress of this research passed to the Multiple Sclerosis Trust following the merger.

Financial review During the sixteen months ended 31 July 2025, the charity changed its financial year to align with that of the Multiple Sclerosis Trust. It therefore ends on 31 July rather than 31 March.

At the 31 July 2025, the charity held nil funds (31 March 2024: £1,096,062). The reason for the decline was that all funds were gifted as an unrestricted donation upon completion of the merger. This donation amounted to £962,157. The charity has now ceased ordinary operating activity, and is no longer expected to hold funds. Any funds it does receive will be gifted to the Multiple Sclerosis Trust. The total income for the sixteen-month period ended 31 July 2025 was £71,063 (year-ended 31 March 2024: £188,962), while the net loss of the charity before transfer of funds to the Multiple Sclerosis Trust, was £133,905 (year-ended 31 March 2024: net surplus: £44,394). The switch from surplus to loss was primarily due to a threeyear research grant being awarded to Sheffield Teaching Hospitals NHS Foundation Trust.

Structure, governance and management The charity is a company limited by guarantee, incorporated on 23 December 1994 and is governed by its Memorandum and Articles of Association.

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M. S. RESEARCH TREATMENT AND EDUCATION LIMITED

TRUSTEES' REPORT (INCLUDING DIRECTORS' REPORT) (CONTINUED)

FOR THE PERIOD ENDED 31 JULY 2025

The trustees, who are also the directors for the purpose of company law, and who served during the period and up to the date of signature of the financial statements were:

B T Clacy C Singleton (Appointed 4 November 2024) The Honourable S L Joiner (Appointed 4 November 2024) B Pagington (Resigned 4 November 2024) O Pagington (Resigned 4 November 2024) N Sood (Resigned 4 November 2024)

None of the trustees has any beneficial interest in the company. All three trustees are also directors of the Multiple Sclerosis Trust.

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All of the trustees are members of the company and guarantee to contribute £1 in the event of a winding up.

The trustees' report was approved by the Board of Trustees.

BT Clacy Trustee

pate: 260.1. 20%.

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M. S. RESEARCH TREATMENT AND EDUCATION LIMITED

INDEPENDENT EXAMINER'S REPORT TO THE TRUSTEES OF M. S. RESEARCH TREATMENT AND EDUCATION LIMITED

| report to the trustees on my examination of the financial statements of M. S. Research Treatment and Education Limited (the charity) for the period ended 31 July 2025.

Responsibilities and basis of report

As the trustees of the charity (and also its directors for the purposes of company law) you are responsible for the preparation of the financial statements in accordance with the requirements of the Companies Act 2006 (the 2006 Act).

Having satisfied myself that the financial statements of the charity are not required to be audited under Part 16 of the 2006 Act and are eligible for independent examination, {| report in respect of my examination of the charity's financial statements carried out under section 145 of the Charities Act 2011 (the 2011 Act). In carrying out my examination | have followed all the applicable Directions given by the Charity Commission under section 145(5)(b) of the 2011 Act.

Independent examiner's statement | have completed my examination. | confirm that no matters have come to my attention in connection with the examination giving me cause to believe that in any material respect:

| have no concerns and have come across no other matters in connection with the examination to which attention should be drawn in this report in order to enable a proper understanding of the financial statements to be reached.

Tracey Richardson BSc (Hons) FCA (Independent Examiner)

For and on Behalf of Azets Audit Services

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Westpoint

Lynch Wood Peterborough Cambridgeshire PE2 6FZ

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M. S. RESEARCH TREATMENT AND EDUCATION LIMITED

STATEMENT OF FINANCIAL ACTIVITIES INCLUDING INCOME AND EXPENDITURE ACCOUNT

FOR THE PERIOD ENDED 31 JULY 2025

Unrestricted Restricted Total Unrestricted Restricted Total
funds funds funds funds
2025 2025 2025 2024 2024 2024
Notes £ £ £ £ £ £
Income from:
Donations and
legacies 3 69,973 - 69,973 186,499 - 186,499
Investments 4 1,090 - 1,090 2,463 2,463
Total income 71,063 - 71,063 188,962 - 188,962
Expenditure
on:
Raising funds
5 31,832 . 31,832 16,977 - 16,977
Charitable activities 6 173,136 - 173,136 127,591 - 127,591
Transfer out to
Multiple Sclerosis
Trust
6 962,157 - 962,157 - - -
Total charitable
expenditure 1,135,293 - 1,135,293 127,591 - 127,591
Total expenditure 1,167,125 - 1,167,125 144,568 - 144,568
Net (outgoing)/incoming
resources before
transfers (1,096,062) - (1,096,062) 44,394 - 44,394
Gross transfers
between funds 500 (500) - - - -
Net (expenditure)/income
forthe period/
Netmovement infunds (1,095,562) (500) (1,096,062) 44,394 - 44,394
Fund balances at 1 April
2024
1,095,562 500 =1,096,062 1,051,168 500 1,051,668
Fund balances at 31 July
2025
- - - 1,095,562 500=1,096,062

The statement of financial activities includes all gains and losses recognised in the period.

All income and expenditure derive from continuing activities.

The statement of financial activities also complies with the requirements for an income and expenditure account under the Companies Act 2006.

ee

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M. S. RESEARCH TREATMENT AND EDUCATION LIMITED

BALANCE SHEET

AS AT 31 JULY 2025

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2025 2024
Notes £ £ £ £
Current assets
Debtors 13 - 3,937
Cash at bank and in hand - 1,101,912
- 1,105,849
Creditors: amounts falling due within
one year 14 - (9,787)
Net current assets - 1,096,062
Income funds
Restricted funds 15 - 500
Unrestricted funds - 1,095,562
- 1,096,062
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The company is entitled to the exemption from the audit requirement contained in section 477 of the Companies Act 2006, for the period ended 31 July 2025.

The directors acknowledge their responsibilities for complying with the requirements of the Companies Act 2006 with respect to accounting records and the preparation of financial statements.

The members have not required the company to obtain an audit of its financial statements for the period in question in accordance with section 476.

These financial statements have been prepared in accordance with the provisions applicable to companies subject to the small companies regime.

The financial statements were approved by the Trustees on OS [or] 22 1G

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Trustee
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Company registration number 03005230

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M. S. RESEARCH TREATMENT AND EDUCATION LIMITED NOTES TO THE FINANCIAL STATEMENTS FOR THE PERIOD ENDED 31 JULY 2025

Charity information

M. S. Research Treatment and Education Limited is a private company limited by guarantee incorporated in England and Wales. The registered office is Spirella Building, Bridge Road, Letchworth, Hertfordshire, SG6 4ET, United Kingdom.

1.1. Reporting period The accounts are for a 16 month period ended 31 July 2025 and consequently information shown in the comparatives which is for a 12 month period may not be entirely comparable.

1.2 Accounting convention The financial statements have been prepared in accordance with the charity's governing document, the Companies Act 2006, FRS 102 “The Financial Reporting Standard applicable in the UK and Republic of Ireland” (“FRS 102”) and the Charities SORP "Accounting and Reporting by Charities: Statement of Recommended Practice applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS 102)" (effective 4 January 2019). The charity is a Public Benefit Entity as defined by FRS 102.

The charity has taken advantage of the provisions in the SORP for charities not to prepare a Statement of Cash Flows.

The financial statements are prepared in sterling, which is the functional currency of the charity. Monetary amounts in these financial statements are rounded to the nearest £.

The financial statements have been prepared under the historical cost convention to include certain financial instruments at fair value. Endif} The principal accounting policies adopted are set out below.

1.3. Going concern On 5 November 2024 the operations, assets and liabilities of the charity were transferred into Multiple Sclerosis Trust (charity number 1088353). Following the transfer the charity has been dormant.

1.4 Charitable funds Unrestricted funds are available for use at the discretion of the trustees in furtherance of their charitable objectives. Restricted funds are subject to specific conditions by donors as to how they may be used. The purposes and uses of the restricted funds are set out in the notes to the financial statements.

1.5 Income Income is recognised when the charity is legally entitled to it after any performance conditions have been met, the amounts can be measured reliably, and it is probable that income will be received. Cash donations are recognised on receipt. Other donations are recognised once the charity has been notified of the donation, unless performance conditions require deferral of the amount. Income tax recoverable in relation to donations received under Gift Aid or deeds of covenant is recognised at the time of the donation. Legacies are recognised on receipt or otherwise if the charity has been notified of an impending distribution, the amount is known, and receipt is expected. If the amount is not known, the legacy is treated as a contingent asset.

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M. S. RESEARCH TREATMENT AND EDUCATION LIMITED

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)

FOR THE PERIOD ENDED 31 JULY 2025

(Continued)

1.6 Expenditure Expenditure is recognised once there is a legal or constructive obligation to transfer economic benefit to a third party, it is probable that a transfer of economic benefits will be required in settlement, and the amount of the obligation can be measured reliably. Expenditure is classified by activity. The costs of each activity are made up of the total of direct costs and shared costs, including support costs involved in undertaking each activity. Direct costs attributable to a single activity are allocated directly to that activity. Shared costs which contribute to more than one activity and support costs which are not attributable to a single activity are apportioned between those activities on a basis consistent with the use of resources. Central staff costs are allocated on the basis of time spent, and depreciation charges are allocated on the portion of the asset's use.

Depreciation is recognised so as to write off the cost or valuation of assets less their residual values over their useful lives on the following bases:

Computers

4 years straight line

The gain or loss arising on the disposal of an asset is determined as the difference between the sale proceeds and the carrying value of the asset, and is recognised in the statement of financial activities.

1.9 Financial instruments

The charity has elected to apply the provisions of Section 11 ‘Basic Financial Instruments’ and Section 12 ‘Other Financial Instruments Issues’ of FRS 102 to all of its financial instruments.

Financial instruments are recognised in the charity's balance sheet when the charity becomes party to the contractual provisions of the instrument.

Financial assets and liabilities are offset, with the net amounts presented in the financial statements, when there is a legally enforceable right to set off the recognised amounts and there is an intention to settle on a net basis or to realise the asset and settle the liability simultaneously.

Basic financial assets

Basic financial assets, which include debtors and cash and bank balances, are initially measured at transaction price including transaction costs and are subsequently carried at amortised cost using the effective interest method unless the arrangement constitutes a financing transaction, where the transaction is measured at the present value of the future receipts discounted at a market rate of interest. Financial assets classified as receivable within one year are not amortised.

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M. S. RESEARCH TREATMENT AND EDUCATION LIMITED

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED) FOR THE PERIOD ENDED 31 JULY 2025

1 Accounting policies

(Continued)

Basic financial liabilities Basic financial liabilities, including creditors and bank loans are initially recognised at transaction price unless the arrangement constitutes a financing transaction, where the debt instrument is measured at the present value of the future payments discounted at a market rate of interest. Financial liabilities classified as payable within one year are not amortised.

Debt instruments are subsequently carried at amortised cost, using the effective interest rate method.

Trade creditors are obligations to pay for goods or services that have been acquired in the ordinary course of operations from suppliers. Amounts payable are classified as current liabilities if payment is due within one year or less. If not, they are presented as non-current liabilities. Trade creditors are recognised initially at transaction price and subsequently measured at amortised cost using the effective interest method.

Derecognition of financial liabilities

Financial liabilities are derecognised when the charity's contractual obligations expire or are discharged or cancelled.

1.10 Employee benefits

The cost of any unused holiday entitlement is recognised in the period in which the employee's services are received.

Termination benefits are recognised immediately as an expense when the charity is demonstrably committed to terminate the employment of an employee or to provide termination benefits.

1.11 Retirement benefits Payments to defined contribution retirement benefit schemes are charged as an expense as they fall due.

2 Critical accounting estimates and judgements

In the application of the charity's accounting policies, the trustees are required to make judgements, estimates and assumptions about the carrying amount of assets and liabilities that are not readily apparent from other sources. The estimates and associated assumptions are based on historical experience and other factors that are considered to be relevant. Actual results may differ from these estimates.

The estimates and underlying assumptions are reviewed on an ongoing basis. Revisions to accounting estimates are recognised in the period in which the estimate is revised where the revision affects only that period, or in the period of the revision and future periods where the revision affects both current and future periods.

3 Donations and legacies

Unrestricted Unrestricted
funds funds
2025 2024
£ £
Donations and gifts 69,168 29,861
Legacies receivable 805 156,638
69,973 186,499

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M. S. RESEARCH TREATMENT AND EDUCATION LIMITED

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED) FOR THE PERIOD ENDED 31 JULY 2025 sh

3 Donations and legacies

(Continued)

Unrestricted Unrestricted
funds funds
2025 2024
£ £
Donations and gifts
Donationsfrom online platforms - 499
Donationsfrom purchasing partners - 625
Regulardonations 14,893 11,199
One-offdonations 54,275 17,538
69,168 29,861
4 Investments
Interest receivable
5 Raisingfunds
Unrestricted Unrestricted
funds funds
2025 2024
£ £
1,090 2,463
Unrestricted Unrestricted
funds funds
2025 2024
£ £
Fundralsi 1 publicit
Otherfundraising costs 234 550
Staffcosts 31,598 16,427
Fundraising and publicity 31,832 16,977
31,832 16,977

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M. S. RESEARCH TREATMENT AND EDUCATION LIMITED

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED) FOR THE PERIOD ENDED 31 JULY 2025

6 Charitable activities

2025 2024
£ £
Staffcosts 1,006 32,347
Depreciation and impairment 174 -
Research registry 999 -
Transferout to Multiple Sclerosis Trust 962,157 -
964,336 32,347
Grantfunding ofactivities (see note 7) 138,633 50,629
Share ofsupport costs (see note 8) 10,578 23,918
Share ofgovernance costs (see note 8) 21,746 20,697
1,135,293 127,591
Grants payable
2025 2024
£ £
Grants to institutions:
UniversityofSheffield 138,633 -
University ofBournemouth - 50,629
138,633 50,629

7 Grants payable

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M. S. RESEARCH TREATMENT AND EDUCATION LIMITED

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED) FOR THE PERIOD ENDED 31 JULY 2025 eaONSO

8 Support costs

Support costscosts
Support Governance 2025 Support Governance 2024
costs costs costs costs
£ £ £ £ £ £
Consultancy
Bankcharges
420
70
-
-
420
70
720
143
-
-
720
143
Office running costs 3,254 - 3,254 11,375 - 11,375
Travel and subsistence - - - 713 - 713
Premises costs 6,834 - 6,834 10,967 - 10,967
Legal and professional - 21,746 21,746 - 17,937 17,937
Accountancy - - - - 2,760 2,760
10,578 21,746 32,324 23,918 20,697 44,615
Analysed between
Charitableactivities 10,578 21,746 32,324 23,918 20,697 44,615

9 Trustees

None of the trustees (or any persons connected with them) received any remuneration or benefits from the charity during the period.

10 Employees

The average monthly number of employees during the period was:

2025 2024
Number Number
3 4
Employment costs 2025 2024
£ £
Wages and salaries 31,598 47,555
Social securitycosts 280 -
Other pension costs 726 1,219
32,604 48,774

There were no employees whose annual remuneration was more than £60,000.

11. Taxation

The charity is exempt from tax on income and gains falling within section 505 of the Taxes Act 1988 or section 252 of the Taxation of Chargeable Gains Act 1992 to the extent that these are applied to its charitable objects.

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M. S. RESEARCH TREATMENT AND EDUCATION LIMITED

NOTES TO THE FINANCIAL STATEMENTS (CONTINUED) FOR THE PERIOD ENDED 31 JULY 2025

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  1. Impairments

Impairment tests have been carried out where appropriate and the following impairment losses have been recognised in profit or loss:

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||||||| |---|---|---|---|---|---| |2025|2024| |In|respect|of:|£|£| |Property,|plant and equipment|174|-| |13|Debtors| |Amounts|2025|2024| |falling due within one year:|£|£| |Other|debtors| |Prepayments|and|accrued|income|-|3,444| |-|493| |-|3,937| |14|Creditors: amounts|falling|due within|one year| |2025|2024| |£|£| |Other|creditors| |Accruals|and|deferred|income|-|5,602| |-|4,185| |-|9,787|

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15 Restricted funds

The income funds of the charity include restricted funds comprising the following unexpended balances of donations and grants held on trust for specific purposes:

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||||||| |---|---|---|---|---|---| |Movement| |in|funds| |Incoming|Balance|at|Transfers|Balance at| |rasources|1|April|2024|31|July 2025| |£|£|£|£| |British|Science Week Grant|-|500|(500)|-|

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British Science Week Grant - To fully fund a Digesting Science event to educate children and families who are directly affected by a family member living with MS.

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M. S. RESEARCH TREATMENT AND EDUCATION LIMITED

NOTES TO THE FINANCIAL. STATEMENTS (CONTINUED) FOR THE PERIOD ENDED 31 JULY 2025

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46 Analysis of net assets between funds
Unrestricted Restricted Total Unrestricted Restricted Total
funds funds funds funds
2025 2025 2025 2024 2024 2024
£ £ £ £ £ £
Fund balances at 31
July 2025 are
representedCurrent assets/(liabilities)by: - - - 1,095,562 500 1,096,062
- : - 1,095,562 500 1,096,062
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47 Related party transactions

There were no disclosable related party transactions during the period (2024 - none).

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