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2023-01-31-accounts

REGISTERED COMPANY NUMBER: 02747551 (England and Wales) REGISTERED CHARITY NUMBER: 1039411

Report of the Trustees and

Unaudited Financial Statements

for the Year Ended 31st January 2023

for

Safer Medicines Trust

Spencer Hyde Limited 272 Regents Park Road London N3 3HN

Safer Medicines Trust

Contents of the Financial Statements for the Year Ended 31st January 2023

Page
Reference and Administrative Details 1
Report of the Trustees 2 to 3
Independent Examiner's Report 4
Statement of Financial Activities 5
Statement of Financial Position 6
Notes to the Financial Statements 7 to 10

Safer Medicines Trust

Reference and Administrative Details for the Year Ended 31st January 2023

TRUSTEES K Archibald J Bailey (resigned 1.2.22) B Gajek C W Edminson COMPANY SECRETARY R Macklin REGISTERED OFFICE 272, Regents Park Road Finchley Central London N3 3HN REGISTERED COMPANY 02747551 (England and Wales) NUMBER REGISTERED CHARITY 1039411 NUMBER INDEPENDENT EXAMINER Spencer Hyde Limited 272 Regents Park Road London N3 3HN

Page 1

Safer Medicines Trust

Report of the Trustees for the Year Ended 31st January 2023

The trustees who are also directors of the charity for the purposes of the Companies Act 2006, present their report with the financial statements of the charity for the year ended 31st January 2023. The trustees have adopted the provisions of Accounting and Reporting by Charities: Statement of Recommended Practice applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS 102) (effective 1 January 2019).

OBJECTIVES AND ACTIVITIES

Objectives and aims

Safer Medicines Trust is established to :-

a) undertake and advance research into the effectiveness and benefit to the general public of medical experiments on animals;

b) provide information and to educate the public as to the results of such research;

c) do any other charitable activity.

ACHIEVEMENT AND PERFORMANCE

Charitable activities and achievements

In March, along with our partners in the Alliance for Human Relevant Science, we helped launch an important report in Parliament by the The All Party Parliamentary Group for Human Relevant Science. In the report: "Bringing back the human: transitioning from animal research to human relevant science in the UK", MPs from the APPG call for a transition to human relevant science to advance medical progress.

In October, again with our Alliance partners, we hosted an exceptional event at the Royal Society of Medicine, entitled "Cancer research - a new paradigm." Chaired by our Patron, Dr James Le Fanu, Professors Azra Raza and Geoff Pilkington gave inspirational talks, followed by riveting discussions with the expert audience.

Our Pharmaceutical Director, Dr Gerry Kenna, presented a virtual seminar on "In vitro models for assessment of drug-induced liver injury (DILI)" to the Liver Toxicity Working Group of the US regulator, the FDA.

Our Scientific Consultant, Rebecca Ram, co-authored a paper on "The role of 'big data' and 'in silico' New Approach Methodologies (NAMs) in ending animal use - a commentary on progress".

Our Research Consultant, Pandora Pound, co-authored a scientific appraisal of animal research over the past 20 years: "The role of systematic reviews in identifying the limitations of preclinical animal research, 2000 - 2022."

Our Director, Jan Turner, co-authored an analysis of the origins of animal safety test requirements and whether they were justified then or now: "A History of Regulatory Animal Testing: What Can We Learn?"

In collaboration with Alliance partners, we led a series of 5 workshops with 13 international experts to identify feasible NAMs and discuss how to use them in specific contexts. The culmination of this work was a published report: "Incorporating new approach methodologies into regulatory nonclinical pharmaceutical safety assessment." We hope others will build on this work and use it to speed the transition to greater human relevance, which is so urgently needed.

After all this work, our Director, Dr Jan Turner, very sadly left to take up a new role with Axol Bioscience but happily, remains one of our Science Advisers. She recorded an excellent podcast about organ-on-chip technology before she left.

All papers, reports, podcasts and presentations are available on our website.

FINANCIAL REVIEW

Reserves policy

The Trustees have resolved to establish reserves with a reputable UK bank for future funding activities of the charity, and the Trustees have powers of investment in such assets as they see fit.

Page 2

Safer Medicines Trust

Report of the Trustees for the Year Ended 31st January 2023

FINANCIAL REVIEW Financial Review

During the year, the Charity raised £26,588 (2021: £150,567) as voluntary donations.

These funds were used to promote the campaigns and educations through attendance at several conferences and events and overhead expenses.

As shown in the Statement of Financial Activities, the Charity still holds £29,720 (2021: £77,322) which will be used as the programmes progress.

STRUCTURE, GOVERNANCE AND MANAGEMENT

Governing document

The Charity is controlled by its governing document, a Memorandum and Articles of Association, and constitutes a limited company, limited by guarantee, as defined by the Companies Act 2006.

The company is limited by guarantee and therefore has no share capital. Each Trustee's guaranteed liability is limited to £1.

It is the view of the Trustees and stated in the Memorandum and Articles of Association that the surplus of funds is not available for distribution to the Trustees but it is for the sole purpose of achieving the main objects of the charitable company.

Recruitment and appointment of new trustees

The management of the charity is the responsibility of the Trustees who are elected and co-opted under the terms of the Articles of Association.

The number of Trustees shall not be less than three but shall not be subject to any maximum. At every Annual General Meeting (AGM), one-third of the Trustees who are subject to retirement by rotation or, if their number is not three or a multiple of three, the number nearest to one-third shall retire from office, but, if there is only one Trustee who is subject to retirement by rotation, he or she shall retire. Additional Trustees can be appointed by recommendation of the existing Trustees or by standing for election at the AGM.

Induction and training of new trustees

All new Trustees, once elected, are inducted by the Chair Trustee, Ms K Archibald. All new Trustees are handed the charity's organisational policies and documents. All Trustees are encouraged to attend regular training courses made available through the NCVO, LVSC and other local voluntary support bodies such as HAVS, as well as utilising online resources for Trustees and attend networking opportunities.

Statement on Public Benefit

The Trustees have referred to the guidance issued by the Charity Commission's general guidance on public benefit when reviewing the Trust's aims and objectives and in planning its future activities.

In particular, we have considered how planned activities will contribute to the aims and objectives set.

This report has been prepared in accordance with the special provisions of Part 15 of the Companies Act 2006 relating to small companies.

Approved by order of the board of trustees on 19th July 2023 and signed on its behalf by:

K Archibald - Trustee

Page 3

Independent Examiner's Report to the Trustees of Safer Medicines Trust

Independent examiner's report to the trustees of Safer Medicines Trust ('the Company')

I report to the charity trustees on my examination of the accounts of the Company for the year ended 31st January 2023.

Responsibilities and basis of report

As the charity's trustees of the Company (and also its directors for the purposes of company law) you are responsible for the preparation of the accounts in accordance with the requirements of the Companies Act 2006 ('the 2006 Act').

Having satisfied myself that the accounts of the Company are not required to be audited under Part 16 of the 2006 Act and are eligible for independent examination, I report in respect of my examination of your charity's accounts as carried out under Section 145 of the Charities Act 2011 ('the 2011 Act'). In carrying out my examination I have followed the Directions given by the Charity Commission under Section 145(5) (b) of the 2011 Act.

Independent examiner's statement

I have completed my examination. I confirm that no matters have come to my attention in connection with the examination giving me cause to believe:

  1. accounting records were not kept in respect of the Company as required by Section 386 of the 2006 Act; or 2. the accounts do not accord with those records; or

  2. the accounts do not comply with the accounting requirements of Section 396 of the 2006 Act other than any requirement that the accounts give a true and fair view which is not a matter considered as part of an independent examination; or

  3. the accounts have not been prepared in accordance with the methods and principles of the Statement of Recommended Practice for accounting and reporting by charities (applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS 102)).

I have no concerns and have come across no other matters in connection with the examination to which attention should be drawn in this report in order to enable a proper understanding of the accounts to be reached.

Antony Youselli

Spencer Hyde Limited 272 Regents Park Road London N3 3HN

19th July 2023

Page 4

Safer Medicines Trust

Statement of Financial Activities for the Year Ended 31st January 2023

2023
Unrestricted
fund
Notes
£
INCOME AND ENDOWMENTS FROM
Donations and legacies
26,588
Investment income
2
75
Other income
3
-
Total
26,663
EXPENDITURE ON
Raising funds
659
Charitable activities
General Activity
73,606
Total
74,265
NET INCOME/(EXPENDITURE)
(47,602)
RECONCILIATION OF FUNDS
Total funds brought forward
77,322
TOTAL FUNDS CARRIED FORWARD
29,720
2022
Total
funds
£
150,567
12
17,064
167,643
593
131,935
132,528
35,115
42,207
77,322

The notes form part of these financial statements

Page 5

Safer Medicines Trust

Statement of Financial Position

31st January 2023

2023
Unrestricted
fund
Notes
£
CURRENT ASSETS
Cash at bank and in hand
30,439
CREDITORS
Amounts falling due within one year
7
(719)
NET CURRENT ASSETS
29,720
TOTAL ASSETS LESS CURRENT
LIABILITIES
29,720
NET ASSETS
29,720
FUNDS
8
Unrestricted funds
29,720
TOTAL FUNDS
29,720
2022
Total
funds
£
79,243
(1,921)
77,322
77,322
77,322
77,322
77,322

The charitable company is entitled to exemption from audit under Section 477 of the Companies Act 2006 for the year ended 31st January 2023.

The members have not required the company to obtain an audit of its financial statements for the year ended 31st January 2023 in accordance with Section 476 of the Companies Act 2006.

The trustees acknowledge their responsibilities for

These financial statements have been prepared in accordance with the provisions applicable to charitable companies subject to the small companies regime.

The financial statements were approved by the Board of Trustees and authorised for issue on 19th July 2023 and were signed on its behalf by:

K Archibald - Trustee

The notes form part of these financial statements

Page 6

Safer Medicines Trust

Notes to the Financial Statements

for the Year Ended 31st January 2023

1. ACCOUNTING POLICIES

Basis of preparing the financial statements

The financial statements of the charitable company, which is a public benefit entity under FRS 102, have been prepared in accordance with the Charities SORP (FRS 102) 'Accounting and Reporting by Charities: Statement of Recommended Practice applicable to charities preparing their accounts in accordance with the Financial Reporting Standard applicable in the UK and Republic of Ireland (FRS 102) (effective 1 January 2019)', Financial Reporting Standard 102 'The Financial Reporting Standard applicable in the UK and Republic of Ireland' and the Companies Act 2006. The financial statements have been prepared under the historical cost convention.

Income

All income is recognised in the Statement of Financial Activities once the charity has entitlement to the funds, it is probable that the income will be received and the amount can be measured reliably.

Expenditure

Liabilities are recognised as expenditure as soon as there is a legal or constructive obligation committing the charity to that expenditure, it is probable that a transfer of economic benefits will be required in settlement and the amount of the obligation can be measured reliably. Expenditure is accounted for on an accruals basis and has been classified under headings that aggregate all cost related to the category. Where costs cannot be directly attributed to particular headings they have been allocated to activities on a basis consistent with the use of resources.

Tangible fixed assets

Depreciation is provided at the following annual rates in order to write off each asset over its estimated useful life.

Computer equipment - 25% on cost

Taxation

The charity is exempt from corporation tax on its charitable activities.

Fund accounting

Unrestricted funds can be used in accordance with the charitable objectives at the discretion of the trustees.

Restricted funds can only be used for particular restricted purposes within the objects of the charity. Restrictions arise when specified by the donor or when funds are raised for particular restricted purposes.

Further explanation of the nature and purpose of each fund is included in the notes to the financial statements.

Pension costs and other post-retirement benefits

The charitable company operates a defined contribution pension scheme. Contributions payable to the charitable company's pension scheme are charged to the Statement of Financial Activities in the period to which they relate.

Vat

The charity is not registered for VAT (Value Added Tax). In common with many other similar charities, the expenses are inflated by VAT, which cannot be recovered.

continued...

Page 7

Safer Medicines Trust

Notes to the Financial Statements - continued for the Year Ended 31st January 2023

2. INVESTMENT INCOME

INVESTMENT INCOME
2023 2022
£ £
Deposit account interest 75 12

3. OTHER INCOME

Included in the accounts is nil, (2021: £17,604) in relation to Government CJRS Grant received during the year.

4. TRUSTEES' REMUNERATION AND BENEFITS

There were no trustees' remuneration or other benefits for the year ended 31st January 2023 nor for the year ended 31st January 2022.

Trustees' expenses

There were no trustees' expenses paid for the year ended 31st January 2023 nor for the year ended 31st January 2022.

5. STAFF COSTS

Included in the accounts is £10,500 (2021: £61,507) paid to Dr Jan Turner for her role as Executive Director.

6. TANGIBLE FIXED ASSETS

TANGIBLE FIXED ASSETS
Computer
equipment
£
COST
At 1st February 2022 and 31st January 2023 2,251
DEPRECIATION
At 1st February 2022 and 31st January 2023 2,251
NET BOOK VALUE
At 31st January 2023 -
At 31st January 2022 -

continued...

Page 8

Safer Medicines Trust

Notes to the Financial Statements - continued for the Year Ended 31st January 2023

7. CREDITORS: AMOUNTS FALLING DUE WITHIN ONE YEAR

Accrued expenses
8.
MOVEMENT IN FUNDS
At 1.2.22
£
Unrestricted funds
General fund
77,322
TOTAL FUNDS
77,322
Net movement in funds, included in the above are as follows:
Incoming
resources
£
Unrestricted funds
General fund
26,663
TOTAL FUNDS
26,663
Comparatives for movement in funds
At 1.2.21
£
Unrestricted funds
General fund
42,207
TOTAL FUNDS
42,207
Comparative net movement in funds, included in the above are as follows:
Incoming
resources
£
Unrestricted funds
General fund
167,643
TOTAL FUNDS
167,643
2023
2022
£
£
719
1,921
Net
movement
At
in funds
31.1.23
£
£
(47,602)
29,720
(47,602)
29,720
Resources
Movement
expended
in funds
£
£
(74,265)
(47,602)
(74,265)
(47,602)
Net
movement
At
in funds
31.1.22
£
£
35,115
77,322
35,115
77,322
Resources
Movement
expended
in funds
£
£
(132,528)
35,115
(132,528)
35,115

continued...

Page 9

Safer Medicines Trust

Notes to the Financial Statements - continued

for the Year Ended 31st January 2023

8. MOVEMENT IN FUNDS - continued

A current year 12 months and prior year 12 months combined position is as follows:

Net
movement At
At 1.2.21 in funds 31.1.23
£ £ £
Unrestricted funds
General fund 42,207 (12,487) 29,720
TOTAL FUNDS 42,207 (12,487) 29,720

A current year 12 months and prior year 12 months combined net movement in funds, included in the above are as follows:

Incoming Resources Movement
resources expended in funds
£ £ £
Unrestricted funds
General fund 194,306 (206,793) (12,487)
TOTAL FUNDS 194,306 (206,793) (12,487)

9. RELATED PARTY DISCLOSURES

There were no related party transactions for the year ended 31st January 2023.

Page 10