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2023-03-31-accounts

REGISTERED CHARITY NUMBER: 1020201 REPORT OF THE TRUSTEES AND UNAUOITED FINANCIALSTATEMENTS FOR THE YEAR ENDED 31 MARCH 2023 FOR THE DAVIO HIDE AsfHMA AND ALLERGY RESEARCH CENTRE 8right Brown Limited Chartered Accountants Exchange House St. Cross Lane Newport Isle of Wlght P030 SBZ

THE DAVID HIDE AsfHMA AND ALLERGY RESEARCH CENTRE CONTENTS OF THE FINANaAL STATEMENTS FOR THE YEAR ENDED 31 MARCH 2023 Page Report of the Trustees Independent E¥aminerfs Report statement of Flnanclal Act￿llIeS Balance Sheet Note5 to the Flnancial Statements 7 to 13 Detalled Statement of Flnanrlal Actlvitles 14 to 15

THE OAVID HIDE ASTHMA AND ALLERGY RESEARCH CENTRE REPORT OF THE TRUSTEES FOR ThE YEAR ENDED 31 MARCH 2023 The trustees present thelr report with the financlal statement5 of the charity for the year ended 31 March 2023. The tru5tee5 have adoptetl the provisions of Accounting and Reportin8 by Charities.. Statement of Recommended Practice applicable to charities preparing their accounts in accordance with the FSnanclal Reporting Standard applicable in the UK and Republlc of Ireland IFRS 1021 (effective l January 20191. OBJECTIVES AND AcTIV￿lES Object5 of the charity The charity provides the opportunity to further the knowledge of diagnosls and management of allergi¢ diseages based on research. It secures the research and education plarform from which much has been achieved in the last two decades. The charity operates from a purpose-bullt centre wlthin St. Mary's Hospital and it5 main functions are.. to provide a facility for diagnosis and rnanagement of allergy-related disorders within the NHS,. to increase the understanLling of ihe causes and treatment of allerBlc dlseases by means of an evolving pro8ramme of research,. and to offer training In Clinbcal allergy to d(Ktors, medical students and other health professionals. In sflaplng our ot)jectives for the year and planning our activities. the trustees have considered the Charity Comrnission's guidance on publlt beneflt. ACHIEVEMENT AND PERFORMANCE Review of the development and achlevement of the d￿rItY In 2022 research activity continued at the David Hide Asthma & Aller8y Centre. The Research team has been reduced over the year to reflect actlvlty but continue to delive¥ to tar8et. Study activlty: Pattems of adult food aller8y in the UK populatlon IPAFA 5taBe 31. funded by the Food Standards Agency IFSAI and sponsored by Manchester University NHS Foundation Tyust. The Davld Hlde Centre carried out recruitment of indsvlduals from the Isle of Wight Birth Cohort who had probable food aller8ies. The Research team had the opportunity to set up a commercial CRN Wessex led Immunisation Study. The Harmonle study is looking at a nEw medicine which protects ag3in5t respiratory syncytial virus IRSVI. The Study Is looklnÈ at how strongly babies can be protetted frtsm serious illness due to RSV infection by comparing a single dose of antibody with no Intervention. The Preschool wheeze study (Breathing Togetherl wa5 complèted, endlng the study by following up the children at 4-5 years of age. EOSA- Epi8enetics of Sèvere Asthma Study re4tarted early in 2023. recrultln8 adults with mild asthma and healthy volunteeTS Ino asthma). Further fvndlng ffom the NIH IUSAI was secured thfough the University of California, Sa Oie@o. FINANCIAL REVIEW Reserves pollcv It 15 the policy of the charity to malntain unrestricted fvnds, which are thè freè reserves of the charlty, at a level whlch equate5 to at least twelve months unrestricted expenditure. At this level the ie5eives provide suffl¢ient funds to continue the activities of the charity. should there be a significant drop in fundin& while new research projects are put in place. In pradiee, the charity holds additional reserves to support over 10 year5 Qf expenditure at the current level held to support the future funding of the charities objectives and to maintain expenditure in a(Jvance of È13nt funding being received. Page I

THE DAVID HIDÈ ASTHMA AND AILERGY RESEARCH CENTRE REPORT OF THE TRUSTEES FOR THE VEAR ENDED 31 MARCH 2023 FINANCIAL REVIEW Result5 for the flnanclal year Total income for the year amounted to £115,71612022.' £66,074). Costs relating to charitable activities amounted to £29,66912022.' £25,735). UnrestrScted funds and restrlcted funds carried forward ai the end of the year amounted to £385,02612022.' £298,979). FUTURE PLANS Planning for future studies continue5: IW 8irth Cohort 34 Year Follow-up will start laier in 2023. PREVENT Prlm3ry Preventlon of Asthma using House Dust Mite Immunotherapy. The proposal will be submitted to thè NIH in September 2023. Applications to the MRC and NIH- related to House Dusi Mite Allergy Food allergy prevention trial- PGfAR- stage 2 application is due to be submitted August 2023. STRUCTURE, GOVERNANCE AND MANAGEMENT Governin8 document The charity 15 CQlltrollefl by its 8overnlng document. a deed of trust and tonstitules an unincorporated charity- Organisatlon The trustees who served during the year are set out below. The trustees meet regularly and meetlngs are presided over by a Chairman who is appoinled annually. REFERENCE AND ADMINisfRATNE DETAILS RegI5tered Charity number 1020201 Principal address The David Hide A5thrna and Allergy Research Centre st Mary's Hospital Newport Isle of Wight P030 STG Tru5tee5 Dr C J A Andrews DrYHHide Mis E M Bell Mfs J A Griffin Dr M R Stainer Mrs S Matthews Mrs C Stone PaÉe 2

INDEPENDENT EXAMINER'S REPORT TO TFIE TRUSTEES OF THE DAVIO HIDE ASTHMA AND ALLERGY RESEARCH CENTRE Independent examinerf5 report to the trustèes olThe Davld Hlde Asthma and Allergy Research Centre I report to the ch3rity trvstees on my examination ol the accounts of The David Hide Asthma and Allergy Re5earth Centre Ithe Trust) for the year ended 31 March 2023. Responslbllhtie5 and b3515 of report As the charty trustees of the Trust you are responslble for the preparatlon of the accounts in accordance with the requirements of the ChaTlties Act 20111.the Act'l. I report in respect of my examlnatlon of the Trtjst's accounts earried out tsn(Jer Sectlon 145 of the Act and in carrying out my examination I have followed 311 appllcable Direction5 given by the Charity Commi551on under Section 14515llbl of the Act. Indèpendent examiner's statement I havÈ completed my examination. I conflrm that no material matters have come to my attention In CDnnettlon wlth the examinatiDn giving ffle cause to believe that in any material respect.. accountlng records were not kept in respect of the Trust as required by 5ertlon 130 of the Act,. or the accounts do not 3ccord with those records; or the accounts do not comply with the applicable requirements concerning the form and content of accounts set out In the CharltSes IAccounts and Reports) Regulations 2008 other than any requlrement that the accoun15 8ive a true and fair view which is not a matter considered as part of an IndopendeTht examlnation. I have no concerns and have come across no other matter5 in connection with the examination to whleh attention shtsuld be drawn In thls report in order to enable a proper understanding of the account5 to be reached. DIPSteveMsACA Bright Brown Limlted Chartered Accountants Sl. Cross Lane Newport P030 5B2 Date: , Pa8È 4

THE DAVID HIDE ASTHMA AND ALLERGY RESEARCH CENfRE REPORT OF THE TRUSTEES FOR THE YEAR ENDEO 31 MARCH 2023 REFERENCE AND AOMINISTRATIVE DETAILS Independent Examiner DIP5tevensACA Bright 8rown Llmlted Chartered Aceount3nts Exchange House St. Cross Lane Newport Isle of Wight P030 5BZ Approved by order of the board of trustees Dn . and slgned on It5 behalf bv.. DrCJAA ws- Trustee Page 3

THE DAVID HIDE ASTHMA AND ALLERGY RESEARCH CENTRE BALANCE SHE 31 MARCH 2023 2023 UnTestrictÈd funds 2022 Total f￿ndS Note5 FIXED ASSEYS Tan£ible asset5 18,452 21,266 CURRENT ASSErs Oebtors Cash at baTrk 519 367,515 126 278,8S5 368,034 278,981 CREDITORS AmotJnt5 falllng due wlthln one yeaf 11,4601 11,2681 NET CURRENT ASSETS 366,574 277,713 TOTAL AS5EtS LESS CUARENT UABILITIES 385,026 298,979 NET ASSETS 385,026 298,979 FUNDS Unrestricted funds 385,026 298,979 TOTAL FUNDS 385,026 298.979 The Inancial statement5 were approved by the Board of TNstee5 and authorised lor issue on .3.......... and were sSgned on Its behalf bv.. Orc drews-Tru5tee The notes form part Lif these financial statements Page 6

THE DAVID HIDE A5THMAAND ALLERGY RESEARCH CENTRE STATEMENT OF FINANCIAL AcnviTIES FOA THE YEAR ENDED 31 MARCH 2023 2023 Unrestricted funds 2022 Total lund5 Notes INCOMEAND ENDOWMENTS FROM Donations and legacies 2,827 4,933 Charltable actlvltle5 Research, dia&inosls and management of allerglc diseases 112,085 60,969 Invèstment Income Other income 779 25 172 Total 115,716 66,074 EXPENDITURÉ ON Charitable actlvltle5 Aesearch, diagnosis and managemelbt of aller8iC diseases 29.669 25,735 N￿]NComE 86.047 40,339 RECONCILIATION OF FUNDS Total funds brought forward 298,979 258,640 TOTAL FUN05 CARRIED FORWARO 385,026 298.979 The notes form part of these flnancial statements Page 5

THE DAVID HIDE ASTHMA ANO ALLERGY RESEARCH CENTRE NOTES TO THE FINANCIAL STATEMENTS FOR THEVEAR ENDED 31 MARCH 2023 ACCOUNTING POLICIES Bas55 of preparlngthe flnanclal statements The financial statements of the charity, which Is a public benefit entity under FRS 102, have been prepared in accordance with the Charities SORP IFRS 1021 'Accounting and Reportlng by Charities.. Statement of Recommended PrJttbce applicable to charitie5 preparing their accounts in accordance wlth the Financial Reportlng Standard applicèble in the UK and Republlc of Ireland IFRS 1021 leffective I january 20191,. Financial Reporting Standard 102 'The Finaftclal Reporting Standard applicable in the UK and Republic of Ireland, and the Charities Act 2011. The financial Statements have been prepared under the historlcal c05t convention. Income All Income is recognlsed in the Statement of Financial Activitle5 once the charity has enlitlempnt to the fund5, it is prabable that the Income wlll be received and the amount can be measurèd reliablv. Empendlture Liabilitie5 are ie¢oEnised as expendlturè as soon as there is a legal or constructive obligation committlng the Charity to that expenditure, it Is probable that a transfer of economic benefits will be required in settlement and the amount of the oblieation can bè measured reliabty. EKpendlture is accounted for on an accruals basls d has been classifled under headings that aggregate all cost related to the categoTY. Wheie costs cannot be dlrectly attributed to particular headings they have been allocated to activities on a basis con51Stent wlth the use of resources. Tan81b￿ fixed assets Depreciation is provided at the folluwin8 annual rates in Ofdgr to write ctff each a55et over its estimated useful Building Equlpment Over fifty years Straight line over 3 to 7 years Fund at¢aunt5ng General Fun The charity's genèral funds consist of funds whlch the charity may use for its purpose5 at tts dlscretion. Restricted Fund5 nwme received into the restricted fund FepresentS the ￿e￿Ipt of funds for specific purposes. Expenditure charged against the restricted lunds represents revenue c05t5 incurred during the year for the purpose specified by the fund. Desi èd Funds Designated fund5 are funds established by the committee from time to time for speclfic projetts or purpL75e5, are not in any way restricted and any 5urplu5 or deficit will bè transferred tolfrom the general purpose fund when the designated fund In dosed. Page 7 continued...

THE DAVID HIDE ASTHMA AND ALLERGY RESEARCH CENTRE NOTES TO THE FINANCIAL STATEMENTS- contlnyed FOR THE YEAR ENDED 31 MARCH 2023 INVESTMEfrIT INCOME 2023 2022 UK Bank interest 779 172 TRUSTEES, REMUNERATION AND BENEFITS There were no trustees, ￿MUneratIOn or other benefits for the year ended 31 March 2023 nor for the year ended 31 March 2022. Trustees, expenses There were no trustees, expenses paid for the year ended 31 March 2023 nor foy the year ended 31 March 2022. STAFF COSTS The average monthw number of employees during the year was as follows.. 2023 2022 Research. dSagnosis and management No ernployeE5 received emolument5 In excess of £60.C￿. All employee c05tS shown above are Contributions to NHS Trust wages that have been recha¥ged to the charity. COMPARATIVES FOR THE STATEME￿ OF FINANCIAL ACTIVITIES Vnre5trlrted funds INCOME AND ENDOWMENTS FROM Donations and legacie5 4,933 Charltable actl¥ltle5 Research, diagnosis and management of 311er8ic diseases 60,969 Investment income 172 Total 66,074 EXPENDITURE ON Charitable artivltle5 Research, cliagnosis and management of aller8ic disease5 25.735 NET INCOME 40,339 Page 8 continued...

THE OAVID HIDE ASTHMA AND ALLERGY RESEARCH CENTRE NOTES TO THE FINANCIAL STATEMENTS- contlnued FOR THE YEAR ENDED 31 MARCH 2023 COMPARATNES FOR THE STATEMENT OF FINANCIAL AcnviriES- Contlnued Unrestricted fvnds RECONCILIATION OF FUNDS Total funds brought forward 258,640 TOTAL FUNDS CARRIED FORWARD 298.979 TANGIBLE FIXED ASSETS Building Equipment Tota15 COST At l April 2022 Dlsposals 30,0 41,185 112,9961 71,185 112,9961 At 31 March 2023 30,OCQ 28,189 58,189 DEPRÉCIATION At l April 2022 Charge for year Ellminated on disposal 15,000 600 34,919 2,215 112,9971 49,919 2,815 112,997 At 31 March 2023 15,600 24,137 39,737 NET BOOK VALUE At 31 March 2023 14.400 4,052 18,452 At 31 March 2022 15,000 6.266 21,266 All of thè fSxed assets are used in the diwecl furtherance of the charity's object4ves. DEBTORS: AMOUTrUS FALLING DUE WITHIN ONE YÉAR 2023 2022 other debtors 519 126 Page 9 continued...

THE OAVID HIDE ASfHMA AND ALIERGY RESEARCH CENTRE NOTES TO THE FINANCIAL STATEMENTS- contSnued FOR THE YEAR ENDED 31 MARCH 2023 CRED￿oR5., AMOUNTS FALLING DUE WITHIN ONE YEAR 2023 2022 Sundry ¢redltors and accrued expenses 1,460 1,268 MOVEMENT IN FUNDS Net movement in fvn(Is At 31.3.23 At 1.4.22 Unrestrlcted funds Resèarch, diagnosis and management of allergic di5ease5 Pl Fund (H Ramesh) Pl Fund IR Kurukulaafatchy} Pl Fund IG Robert51 258,(K)9 9,121 18.829 13,020 89,182 19361 14,0171 1,818 347,191 8,185 14,812 14,838 298.979 86,047 385,026 TOTAL FUNDS 298,979 86,047 385.026 Net movement in fund5, inclknded in the above are as follows.. Incomlng resources Resources expended Movement in funL45 Unre5trIcted funds Research, dlagnosls and management of allergic disea5e5 Pl Fund (H Rameshl Pl Fund IR Kurukulaaratchyl Pl Fund IG Roberts) 101,732 112,5501 19361 15,6691 110,5141 89,182 19361 14,0171 1,818 1,652 12,332 115,716 129,6691 86,047 TOTAL FUNDS 115,716 129,6691 86,047 Page 10 gntinued...

THE DAVID HIDE ASTHMA AND ALIERGY RESEARCH CENTRE NOTES TO THE FINANCIAL STATEMENTS- contlnued FOR THE YEAR ENDED 31 MARCH 2023 MOVEMENT IN FUNDS- contlnued Comparatl¥esfoY movement In funils Net movement in fund5 At 31.3.22 At 1.4.21 Unrestrlrted fvnds Research, diagnosis and managemenl of Ilerglc diseases Pl Fund (H Rameshl Pl Fund IR Kurukulaaratchyl Pl Fund IG Roberts) 233.639 9,121 13,480 2.400 24,370 258,009 9,121 18,829 13,020 5,349 10,620 258,640 40,339 298,979 TOTAL FUNDS 258,640 40.339 298,979 Comparatlve net movement in funds, included in the above are as follows.. Incoming resources Resources expended Movement In funds Unrestrirted fvnds Research, diagnosis and management of allergic diseases Pl Fund IR Kurukulaaratchyl Pl Fund IG Robert51 50,105 5,349 10,620 125,7351 24,370 5,349 10,620 66,074 125,7351 40,339 TOTAL FUNDS 66,074 12S,7351 40,339 Page 11 continued...

THE DAVID HIDE ASTHMA ANO ALLERGY RESEARCH CENTRE NOTES TO THE FINANCIAI STATEMENTS- contlnued FOR THE YEAR ENDED 31 MARCH 2023 MOVEMENT IN FUNDS- continued A current year 12 month5 and prior year 12 month5 ¢omblned position is as follows.. Net movement in furbds At 31.3.23 At 1.4.21 UnrestrSrted funds Research, di38nosis and management of allergic diseases Pl Fund IH Rameshl Pl Fund IR Kurukulaaratchyl Pl Fund IG Roberts) 233,639 9,121 13,480 113,552 19361 1,332 12,438 347.191 8,185 14,812 14,838 258,640 126,386 385,026 TOTAL FUNDS 258,640 126,386 385,026 A current year 12 months and prior year 12 months combined net movement in funds, Included in the above are as follows.. Incoming resources ResourtÈs expended Movement in funds Unrestrlrted funds Research, diagnosis and management of allerÉic diseases Pl Fund IH Ramesh) Pl Fund IR Kurukulaar3tchvl Pl Fund IG ftobertsl 151,837 138,2851 19361 15,6691 110,5141 113,552 19361 1,332 12,438 7,001 22.952 181,790 155,4041 126,386 TOTAL FUNDS 181,790 155,4041 126,386 The research. diagnosis and mana8ement of allergic dlsease5 fund 5s made up of fund5, les5 related expendlture, for the continuance of the educational work undertaken by the Eentie. Expense5 may in¢ludè subscrlptions to asthma and allergy related organi5ation5, attending meetings. courses and conference5 Including re81Stration. travel expenses and accommodation. It will also fund the purchase of relevant journals and books for the Centre library. The Pl Funds are designated funds made up of funds, less related expenditure, for research by Dr Hasan and Dr Ramesh. Expensès will be allocated at the discretion of the dottors. Page 12 conilnued...

THE DAVID HIDE ASTHMA AND ALLERGY RESEARCH CENTRE NOTES TO THE FINANCIAL STATEMENT5- ¢ontlnued FOR THE YEAR ENDED 31 MARCH 2023 io. RELATED PARTY DISCLOSURES Thère were no ielated part.y transactions for the year ended 31 Marrh 2023. Ll. ANALYSIS OF NET A55ETS BETWEEN FLITrIOS TanÈible flxed assets Net current assets Total Restricted fvnds.. Unrestrlcted funds: 29,805 257,960 287,765 29,805 257,960 287,765 Page 13

THE DAVID HIDE ASTHMA ANO ALLERGY RESEARCH cE￿rRE OETAILED STATEMENT OF FINANCIAL AcnviTIES FOR THE YEAR ENOED 31 MARCH 2023 2023 Total funds 2022 Total funds INCOME AND ENDOWMENTS Donatlons and le&acles Donations Pollen fundin8 300 2,527 300 4.633 2,827 4.933 Investment In¢ome UK Bank inteFe5t 779 172 Charltable a¢ti¥lties Grants Pl Ftjnd 98,101 13,984 45.000 15,969 112,085 60,969 Othpr Income Othèr income 25 Total Sncomlng resources 115,716 66,074 EXPENDITURE Charitable activltle5 Telephone and internet Postage and statiorbery Mlscellaneous Travel Gifts. vouchers and refreshmènts Medic31 supplies and repairs Financial service5 Course and conferènce costs Subscription5 l.T costs Contrlbution to Dy50n BreathinK together charge studentship support Depreciation of tangible fixed èssets Loss on sale of tangible fixed a55ets 436 125 1,456 536 500 4,898 1,890 301 415 2,593 102 7,342 1,932 185 4,924 1,500 5.931 10,329 2,814 2,814 1,701 28,493 24.631 This page doe5 not form part of the statutory financial Statements Page 14

THE DAVID HIDE ASTHMA AND ALLERGY RESEARCH CENTRE DETAILED STATEMENT OF FINANCIALACTIVITIES FOR THE YEAR ENOED 31 MARCH 2023 2023 Total funds 2022 Total funds Support costs Governince costs Independènt ex3mlners fees 1,176 1.104 Total resources expèndèd 29,669 25,735 Net Income 86,047 40,339 This page doe5 Ilot form part of the statutory financial statements Page 15