Chari
Number 1007819
THE RALPH BATES PANCREATIC CANCER RESEARCH FUND
UNAUDITED ANNUAL REPORT AND FINANCIAL STATEMENTS
FOR THE YEAR ENDED
31" MARCH 2022

THE RALPH BATES PANCREATIC CANCER RESEARCH FUND
Chari
no: l(K17819
CONTENTS
PAGE I
CONSTITUTION. TRUSTEES AND ADVISORS
PAGE2-3
TRUSTEES'REPORT
PAGE 4
INDEPENDENT EXAMINER'S REPORT
PAGE 5
STATEMENT OF FINANCIAL ACTIVITIES
PAGE 6
BALANCE SHEET
PAGE 7- 10
NOTES TO THE FINANCIAL STATEMENTS

THE RALPH BATES PANCREATIC CANCER RESEARCH FUND
Chari
No: 11)07819
PAGE I
CONSTITUTION
The Ralph Bates Pancreatic Cancer Research Fund is a Registered Charity, No 1007819 and
was formed on 17 January 1992. The fund is governed by a Trust Deed and managed by the
Trustees.
PATRON AND TRUSTEE
SIR PETER BLAKE CBE. RDI,RA
TRUSTEES
Mrs Virginia Bates
Dr John Glees MD, FRCR
Mr MSchael Bridge FCA
Mrs Sharon Sullivan
Mr Nigel Baly Bsc, MRICS
Mr Les Biggs ACIS I Secretary)
BANKERS
HSBC Bank PLC, 9 High Street, Ketterin& Northants, NN16 85T
INDEPENDENT EXAMINER
Mr C W Soper FCCA, 20 Furzen Close, Dunstable.Beds.LU6 3EN
LEGAL ADVISERS
Edwln Coe, 3 Stone Buildings, Llncolns Inn, London, WC2 3TH
REGISTERED ADDRESS
St Georges University of London, Jenner Win& Cranmer Terrace. London. SW17 ORE
ADMINISTRATION ADDRESS
317 Old Bedford Road. Luton. Beds. LU2 7BL

THE RALPH BATE5 PANCREATIC CANCER RESEARCH FUND
Chari
No:1007819
PAGE 2
TRUSTEES, REPORT
The Trustees are pleased to present their report for the year ended 31 March 2022.
OBJECTIVES AND ORGANISATION OF THE CHARITY
The Charity was constituted under a Trust Deed dated 17 January 1992, the principle
otsiectives of which are:
-Both caplt31 and Income of the Fund shall be applied by the Trustees for all or any of the
followin8 purpose5:.
al To promote research into pancreatic cancer and associated diseases, disabilitles and
conditions by way of 8rant, remuneration, loan5, or other assistance for persons,
hospitals, universities, colleges. institutions, corporate bodie5, charities, trust or
other engaged in such research.
bl To carry out or participate in such research directly.
cl To provide relief and comfort for pancreatic cancer sufferers either directly or
through any hospital, charity, institution or other party en8aged in such work.
dl To establish, endow, fund or assist fellowship bursaries or Scholarships linked with
the name Ralph Bates and tenable by persons engaged wholly or mainly In
pancreatic cancer research or treatment.
The Trustees who served in the year are set out on Page l of the financial statements.
There are no subcommittees. The existin8 Board of Trustees is responsible for appolntlng
other Trustees. When considering candidates, the Trustees take Into account any
professional qualifications, clinical or other relevant experience and the candidate's
potential contribution to the Charity.
The Trustees have been mindful of, and ensured that, the Charity has acted in accordance
wlth the Charity Commission's guidance as pertains to public benefit.
REVIEW OF AcficiTIES ACHIEVEMENTS ANO FufuRE PLANS
Followin8 the lockdowns caused by the Coronavirus pandemic, our research at St. George's
Unlversity of London, recommenced in February 2021. During the lockdowns, our research
team did what they could to keep the research moving, by analyzing data and carrying out
mini projects on cancer cells, which meant they were able to pick up their research without
delay.
Our research had previously shown that treating pancreatic cancer cells with a combination
of gemcitabine Ithe usual treatment) and cytokine. TRAIL. significantly reduced both cell
viability and survival.
During the year, the team examined the effect5 Qf this combination over varyin8 treatment
times. Three cell lines were established and all three demonstrated different responses
over a six hour period of treatment with the cytokine.

THE RALPH BATES PANCREATIC CANCER RESEARCH FUND
Chari
No:1007819
PAGE 2
TRUSTEES, REPORT- Continued.
At a treatment time of four hours, one cell line indicated a survival rate of around 41%, a
significant improvement over the six hour treatment. Other line indicated a minimum of
approximately 49%.
This was an encouraging sign and in July 2022, a paper detailing the research and the
results was published in the International Journal of Molecular Sciences. a hiEhlv respected.
peer reviewed, open access journal published on line.
Donation5, although slower than we would have Ilked at the beginning of the year, plcked
up later on and with continuinB tight control at St Geor8e's. we feel able to continue this
important research.
FINANCIAL REVIEW
During the year donations and other Income amounted to £26,92312021 - £11.0811 and
expenditure was £2,359 12021 - £2,157) leavin8 a surplus of £24,564 12021
surplus of
£8,924), which is transferred to the Unrestricted Funds brought forward which stand at
£36,24912021- £11,685).
After making appropriate enquiries the Trustees have a reasonable expectation that the
Charity has adequate resources to continue in operational existence for the foreseeable
future. This includes consideration of the Impact of COVID-19. Fundralslng tradltlonally
varles from year to year but ha5 been affected by COVID-19 however It Is too early to
determine the longer term Impart on fund raising. The principle Item of expenditure is the
funding of research which has itself been affected by COVID-19 and has delayed costs. Even
if the Charity received no further Income (which the Trustees regard as m05t unlikely) the
Charlty can sustain a comparable level of actlvlty for the next two ye3r5 at least. For thSs
reason, they contlnue to adopt the 8oln8 concern basis in preparln8 the flnanclal
statements.
The Trustees recognize that whilst there is some uncertainty, there is not deemed to be a
material uncertainty on the charl￿S ability to continue as a going concern.

THE RALPH BATES PANCREATIC CANCER RESEARCH FUND
Chari
No:1007819
PAGE 3
TRUSTEES. REPORT- Continued.
RESERVES POUCY
The Trustees attempt to retain sufficient Income reserves to enable the fundlng
known and potential expenditure of future research into pancreatic cancer and associated
dlseases. disabilities and conditlons.
RISK MANAGEMEKr
The Trustees have assessed the major risks to which the Charlty Is exposed, in particular
those related to the operations and finances of the Charity, and are 5at15fied that system5
and procedures are in place to mitigate the Charitws exposure to the major risks. Thls
includes consideration in 2021-2022 and 2021>2021 of the impart of COVIDI9.
Slgned on behalf of the Board
L R BIGGS- Trustee
Dated: 11 LL .

THE RALPH BATES PANCREATIC CANCER RESEARCH FUND
Chari
No:1007819
PAGE 4
INDEPENDENT EXAMINERS REPORT
report to the trustees on my examination of the accounts of the Charity for the year
ended 31 March 2022, which are set out on pages 5 to 10.
This report is made solely to the Charitrfs Trustees. as a body, in accordance with
Regulation 31 of the Charitie5 { Accounts and Reports) Regulations 2008. My work has been
undertaken so that I mlght slate to the chariws I rustees those matter5 1 am required to
state to them in an Independent examinerfs report and for no other purpose. To the fullest
extent permltted by law. I do not accept responsibility to anyone other than the Charity's
Trustees as a body, for my work, for this report, or the statement I have made.
RESPONSIBILITIES AND BASIS OF REPORT
As the Charity Trustees you are responsible for the preparation of the accounts In
accordance with the requirements of the Charitles Act 20111 "the Acri.
I report in respect of my examination of the Charity's Account5 carrled out under sectlon
145 of the 2011 Act and in carrylng out my examination I have followed all applicable
Dlrectlon5 given by the Charlty Commission under section 145{511bl of the Act.
INDEPENDENT EXAMINE*S STATEMENT
I have completed my examination. I confirm that no material matters have come to my
attention in connertlon with the examinatlon 8lvSn8 me cause to believe:
a} Accounting records were not kept in respect of the Charity as require by sectlon 130
of the Act,. or
bl The accounts do not accord with those records; or
cl The accounts do not comply with the accountin8 requirements concernin8 the form
and content of the accounts set out in the Charltles l Account5 and Reports)
Regulatlons 2008 other than any requirement that the accounts 8ive a 'true and falr
vlew which Is not a matter considered as part of an Independent examination; or
dl The accounts have not been prepared in accordance with the methods and
principles of the Statement of Recommended Practice for accountin8 and reportin8
charities applicable to charities preparing their accounts in accordance wlth the
Financial Reporting Standard applicable in the UK and the Republic of Ireland I
FRS1021.
I have no concerns and have come acr055 no other matters In connection with the
examination to which attention should be drawn in this report in order to enable a proper
understanding of the accounts to be reached.
Dated:
C W SOPER FCCA
Chartered Certified Accountant
20 Furzen Close
Dunstable
LU6 3EN

RALPH BATES PANCREATIC CANCER RESEARCH FUND
Char
No:1007819
PAGE 5
FINANCIAL ACTIVITIES FOR THE YEAR ENDED 3tst MARCH 2022
As Restoted
Total
Funds
Llnrestrirted
Funds
2022
Total
Funds
2022
2021
INCOME FROM
Donatlons and Legacies I Inc Gift Aldl
Investment Ineome
£26,911
£12
£26,911
£12
£ii,Q41
£40
TOTAL
£26,923
£26,923
Ell.081
EXPENDITURE ON
Ralslng Funds
Charltable ActivitSes
£1,510
£849
£1,510
E849
£712
£1,445
TOTAL
£2.359
£2,359
£2,157
NET INCOME/EXPENDITURE
£24.564
£24,564
£8,924
FUNDS BALANCES BIFwd
£11,685
£11,685
£2, 761
FUNDS BALANCES C/Fwd
£36,249
£36,249
£11,685
All amounts derlve from contlnulng actlvltles.
The statement of flnancial actlvitles Indudes all gains and losses reco8nlsed In the year.

RALPH BATES PANCREATIC CANCER RESEARCH FUND
Chari
No:1007819
PAGE 6
BALANCE SHEEf AS AT 31 MARCH 2022
Note
2022
ZOZ2
2021
2021
CURRENT ASSETS
Debtors
Cash at Bank and in Hand
£2,831
£65,413
£2,563
£89, 779
£68,244
£92,342
CREDITORS
Amounts Fallln8 due within one Year
£31,995
£11,731
NEf CURRENT ASSETS
£36,249
£80,611
Amounts Fallin8 due after more than one yeai
£0
£68,926
NET ASSETS
£36,249
£11,685
Represented by:
UNRESTRicfED FUNDS
io
£36,249
£11,685
£36,249
£11,685
The flnancial statements were approved and authorised for issue by the Trustees on:
Date-..
V Bate5 ..
.Chairper50n
L R Biggs......,.....
..Tru5tee

THE RALPH BATES PANCREATIC CANCER RESEARCH FUND
Chari
No:1007819
PAGE 7
NOTES TO THE ACCOUNTS
I. ACCOUNTING POLICIES
la} The Charity is registered in England and Wales. The financial statements have been
prepared under the historical basis. The financial statements have been prepared in
accordance with the Charities Act 2011, the Statement of Recommended Prattice
applicable to the charitie5 preparing their accounts in accordance with the Financial
Reporting Standard applicable in the UK and the Republic of Ireland I the FRS 102
Charities SORP).
The charity constitutes a public benefit entity as defined by FRS 102.
The financial statements are presented in sterling and are rounded to the nearest
pound.
The financial statements have been prepared to give a 'true and fairf view and have
departed from the Charities (Accounts and Reports) Regulations 2008 only to the
extent required to provide a 'true and fairf view. This departure has involved
following the Charities SQRP IFRS 102} published l January 2019 rather than the
Accounting and Reporting by Charities.. Statement of Recommended Practice
effertive from l April 2(JJ5 which has been withdrawn.
Ib) Going Concern
The Trustees confirm that at the time of approving the financial
statements, there are no material uncertainties regarding the Charitvs ability to
continue in operational existence for the foreseeable future .In arriving at thi5
conclusion, The Trustees have taken account of current and anticipated financial
performance in the current economic conditions. its Corporate Plan and its reserves
position as referred in the Trustees report.
Ic} Donations are included in the statement of financial activities when received. except
donations from sponsorship of events which are accounted in the year in which the
event takes place. Bank interest is included in the statement of financial activities on
the basis of the amount receivable in respect of each financial year.
Idl Expenditure is included in the financial statements when incurred. except cost5
related to fund raising events which are accounted for in the year in which the event
takes place. Grants for research are included when a legal obligation arises.
lel Restricted funds comprise monies received subject to specific conditions required by
the donor and binding on the Trustees and relate to 3 specific research project.
Unrestricted funds are made up of all other donations and interest and are for
general use.
If) The charity only has financial assets and liabilities that qualify as basic financial
instruments. Basic financial instruments are initially recognized at transaction value
and subsequently measured at their settlement value.
(g) Short term debtors are measured at transaction price. less any impairment. Loans
receivable are measured initially at a fair value, net of transattion costs, and are
measured subsequently at amortized cost U5in8 the effective interest method, less
any impairment.

THE RALPH BATES PANCREATIC CANCER RESEARCH FUND
Charl
No:1007819
PAGE 8
NOTES TO THE ACCOUNTS
Continued
Ihl Cash is represented by cash in hand and deposits with financial institutions
repayable without penalty on notice of not more than 24 hours. Cash equivalents
are highly liquid investments that mature in no more than three months from the
date of acquisition and that are readily convertible to known amounts of cash within
slgnificant risk of change of value.
{il Short term creditors are measured at the transaction price. Other financial Ilabllities
including bank loans are measured initially at fair value, net of transaction cost5, and
are measured subsequently at amortized cost using the effective interest method.
2. JUDGEMENTS IN APPLYING THE ACCOUNTING POLICIES AND KEY SOURCE5 OF
ESTIMATION UNCERTAINTY.
In the application of the trust's accounting policies, the trustees are require to make
Judgments, estlmate5 and assumptions about the carrying amounts of assets and
liabilities that are not readily apparent from other sources. The estimates and
associated assumptions are based on historical experience and other factors that
are considered to be relevant. Actual results may differ from these estimates.
The estlmates and underlyin8 assumption5 are revlewed on an on8oln8 basls,
Revislons to actounting estimates are recognized in the period in which the estimate
Is revlsed If the revision affects only that period or in the period of the revision and
future periods if the revision affects both current and future periods.
There were no judgement or material estimation uncertalnties affecting the
reported financial performance in the current or prior year.
3. REMUNERATION AND EXPENSES OF THE TRUSTEES.
None of the Trustees received any remuneration for thelr servlces or reimbursement
for expenses Incurred during the year.12021 £nill.
4.EMPLOYEES
The charity does not employ any staff. During the year there were 7 Trustees12021- 71.

THE RALPH BATES PANCREATIC CANCER RESEARCH FUND
Chari
No:1007819
PAGE 9
NOTES TO THE ACCOUNTS
Contlnued
5. RESOURCES EXPENDED
Unrestricted
Funds
2022
2021
Expenditure on Raising Funds
Website, online agency costs, event
Entry costs and commissions
1,536
1,445
Expenditure on Charitable Activitles
Research studentship and tuition fee5 at:
St George's University of London
Imperial College London
Independent Examiners Fees
521
500
Prlnting, Posta8e , Stationery,
Telephone and Mlscellaneous Items
301
212
2,358
2,157